Search of human proteins with 56788411

Search of human proteins with 56788411

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56788411 interleukin 4 receptor alpha chain isoform b
precursor [Homo sapiens]
         (227 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56788411 interleukin 4 receptor alpha chain isoform b precurs...   488   e-138
gi|4557669 interleukin 4 receptor alpha chain isoform a precurso...   481   e-136
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    49   5e-06
gi|31083174 interleukin 21 receptor precursor [Homo sapiens]           45   4e-05
gi|11141869 interleukin 21 receptor precursor [Homo sapiens]           45   4e-05
gi|31083180 interleukin 21 receptor precursor [Homo sapiens]           45   4e-05
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ...    40   0.001
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ...    40   0.001
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]      35   0.053
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...    33   0.20 
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...    33   0.20 
gi|104487002 protein tyrosine phosphatase, receptor type, D isof...    32   0.34 
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor...    32   0.34 
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo...    32   0.34 
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...    32   0.34 
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo...    32   0.34 
gi|51093381 leptin receptor isoform 3 [Homo sapiens]                   32   0.45 
gi|51093379 leptin receptor isoform 2 [Homo sapiens]                   32   0.45 
gi|40254464 leptin receptor isoform 1 [Homo sapiens]                   32   0.45 
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi...    32   0.45 
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap...    32   0.45 
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]             31   0.76 
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]         31   0.76 
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]         31   0.76 
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]         31   0.76 
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]             31   0.76 
gi|28610151 interleukin 7 receptor precursor [Homo sapiens]            31   0.99 
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]            30   1.3  
gi|140560917 myomesin 1 isoform b [Homo sapiens]                       30   1.3  
gi|140560919 myomesin 1 isoform a [Homo sapiens]                       30   1.3  

>gi|56788411 interleukin 4 receptor alpha chain isoform b precursor
           [Homo sapiens]
          Length = 227

 Score =  488 bits (1256), Expect = e-138
 Identities = 227/227 (100%), Positives = 227/227 (100%)

Query: 1   MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60
           MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL
Sbjct: 1   MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60

Query: 61  LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120
           LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH
Sbjct: 61  LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120

Query: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
           VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL
Sbjct: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180

Query: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSNIC 227
           EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSNIC
Sbjct: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSNIC 227


>gi|4557669 interleukin 4 receptor alpha chain isoform a precursor
           [Homo sapiens]
          Length = 825

 Score =  481 bits (1237), Expect = e-136
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60
           MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL
Sbjct: 1   MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRL 60

Query: 61  LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120
           LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH
Sbjct: 61  LYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEH 120

Query: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
           VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL
Sbjct: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180

Query: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNS 224
           EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNS
Sbjct: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNS 224


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 48/204 (23%), Positives = 77/204 (37%), Gaps = 17/204 (8%)

Query: 30  QEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCV---- 85
           Q   C  D  ++ +C W++      S    L Y+      E   C P    G G +    
Sbjct: 246 QNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEE-CSPVLREGLGSLHTRH 304

Query: 86  -CHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWS 144
            C + + D  +   Y + +   Q    +   K S +++  AP +L V T   D+  L W 
Sbjct: 305 HCQIPVPDPATHGQYIVSV---QPRRAEKHIKSSVNIQ-MAPPSLNV-TKDGDSYSLRWE 359

Query: 145 NPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISY--RARVR 202
                    Y H+ +   I    D A ++      L+ +  +A   L+    Y  R RVR
Sbjct: 360 TM----KMRYEHIDHTFEIQYRKDTATWKDSKTETLQNAHSMALPALEPSTRYWARVRVR 415

Query: 203 AWAQCYNTTWSEWSPSTKWHNSNI 226
                YN  WSEWS +  W   ++
Sbjct: 416 TSRTGYNGIWSEWSEARSWDTESV 439



 Score = 31.2 bits (69), Expect = 0.76
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 10/125 (8%)

Query: 29  LQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTC-IPENNGGAGCV-- 85
           LQ   C +DY S  TC W           + L+ ++   L E  +C + ++   + C   
Sbjct: 30  LQTLRCYNDYTSHITCRWADTQDAQRLVNVTLIRRVNEDLLEPVSCDLSDDMPWSACPHP 89

Query: 86  ------CHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTL 139
                 C +     V  D         + L  + +   ++HV+P  P +L + T+  D  
Sbjct: 90  RCVPRRCVIPCQSFVVTDVDYFSFQPDRPLGTRLTVTLTQHVQPPEPRDLQISTD-QDHF 148

Query: 140 LLTWS 144
           LLTWS
Sbjct: 149 LLTWS 153


>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 15/196 (7%)

Query: 34  CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
           C +DY+    C  +M      +  L    Q   L  EA +C       N   A   CH+ 
Sbjct: 25  CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84

Query: 90  MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
           +   ++ D +++++   +G      GSF  +E +KP  P N+TV    S    ++W + Y
Sbjct: 85  VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142

Query: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
             P    L   L Y +   +  DP     R   ++    S+ +     +   SY  +VRA
Sbjct: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202

Query: 204 W---AQCYNTTWSEWS 216
                  Y  TWSEWS
Sbjct: 203 GPMPGSSYQGTWSEWS 218


>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 15/196 (7%)

Query: 34  CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
           C +DY+    C  +M      +  L    Q   L  EA +C       N   A   CH+ 
Sbjct: 25  CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84

Query: 90  MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
           +   ++ D +++++   +G      GSF  +E +KP  P N+TV    S    ++W + Y
Sbjct: 85  VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142

Query: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
             P    L   L Y +   +  DP     R   ++    S+ +     +   SY  +VRA
Sbjct: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202

Query: 204 W---AQCYNTTWSEWS 216
                  Y  TWSEWS
Sbjct: 203 GPMPGSSYQGTWSEWS 218


>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 15/196 (7%)

Query: 34  CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCI----PENNGGAGCVCHLL 89
           C +DY+    C  +M      +  L    Q   L  EA +C       N   A   CH+ 
Sbjct: 25  CYTDYLQTVICILEMWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNATHATYTCHMD 84

Query: 90  MDDVVSADNYTLDLW--AGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPY 147
           +   ++ D +++++   +G      GSF  +E +KP  P N+TV    S    ++W + Y
Sbjct: 85  VFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQYNISWRSDY 142

Query: 148 --PPDNYLYNHLTYAVNIWSENDP--ADFRIYNVTYLEPSLRIAASTLKSGISYRARVRA 203
             P    L   L Y +   +  DP     R   ++    S+ +     +   SY  +VRA
Sbjct: 143 EDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKDSSYELQVRA 202

Query: 204 W---AQCYNTTWSEWS 216
                  Y  TWSEWS
Sbjct: 203 GPMPGSSYQGTWSEWS 218


>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
           [Homo sapiens]
          Length = 329

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 13/109 (11%)

Query: 114 SFKPSEHVKPRAPGNLTV--HTNVSDTLLLTWSNPYPPD----NYLYNHLTYAVNIWSEN 167
           +F P   VKP  P NL+V     +S  L LTW+NP         Y   + T   + WS+ 
Sbjct: 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI 272

Query: 168 DPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWS 216
            P D      ++           LK    Y  R+R   +     WS+WS
Sbjct: 273 PPEDTASTRSSF-------TVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314


>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
           [Homo sapiens]
          Length = 918

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 13/109 (11%)

Query: 114 SFKPSEHVKPRAPGNLTV--HTNVSDTLLLTWSNPYPPD----NYLYNHLTYAVNIWSEN 167
           +F P   VKP  P NL+V     +S  L LTW+NP         Y   + T   + WS+ 
Sbjct: 213 NFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQI 272

Query: 168 DPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWS 216
            P D      ++           LK    Y  R+R   +     WS+WS
Sbjct: 273 PPEDTASTRSSF-------TVQDLKPFTEYVFRIRCMKEDGKGYWSDWS 314


>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
          Length = 369

 Score = 35.0 bits (79), Expect = 0.053
 Identities = 29/102 (28%), Positives = 40/102 (39%), Gaps = 8/102 (7%)

Query: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
           V P AP NLT+H      L L W+N +   N+   HL      W  +       Y   + 
Sbjct: 152 VIPWAPENLTLHKLSESQLELNWNNRFL--NHCLEHLVQYRTDWDHSWTEQSVDYRHKFS 209

Query: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTT-WSEWSPSTKW 221
            PS+       +   ++R R R    C +   WSEWS    W
Sbjct: 210 LPSV-----DGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHW 246


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 33.1 bits (74), Expect = 0.20
 Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 16/125 (12%)

Query: 88  LLMDDVVSADNYTLDLWAGQQLLWKGSFKP-----SEHVKPRAPGNLTVHTNVS---DTL 139
           + + D+++   YT ++ A   +  +  F P     +      AP  +++   VS   D++
Sbjct: 393 IYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSI 452

Query: 140 LLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLE-PSLRIAASTLKSGISYR 198
            L+WS P  P+  +   L Y +  + +    +   YN T ++ P+  +    LK+G  Y 
Sbjct: 453 TLSWSQPDQPNGVI---LDYELQYYEK----ELSEYNATAIKSPTNTVTVQGLKAGAIYV 505

Query: 199 ARVRA 203
            +VRA
Sbjct: 506 FQVRA 510


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 33.1 bits (74), Expect = 0.20
 Identities = 29/125 (23%), Positives = 57/125 (45%), Gaps = 16/125 (12%)

Query: 88  LLMDDVVSADNYTLDLWAGQQLLWKGSFKP-----SEHVKPRAPGNLTVHTNVS---DTL 139
           + + D+++   YT ++ A   +  +  F P     +      AP  +++   VS   D++
Sbjct: 393 IYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSI 452

Query: 140 LLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLE-PSLRIAASTLKSGISYR 198
            L+WS P  P+  +   L Y +  + +    +   YN T ++ P+  +    LK+G  Y 
Sbjct: 453 TLSWSQPDQPNGVI---LDYELQYYEK----ELSEYNATAIKSPTNTVTVQGLKAGAIYV 505

Query: 199 ARVRA 203
            +VRA
Sbjct: 506 FQVRA 510


>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform
           5 precursor [Homo sapiens]
          Length = 1502

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 11/84 (13%)

Query: 118 SEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTY-------AVNIWSENDPA 170
           SE     AP ++      S T+L+ W  P  P+  +  +  Y        VN W +++ A
Sbjct: 410 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 469

Query: 171 DFRIYNVTYLEP----SLRIAAST 190
           D +I  +  L P    S+++ A T
Sbjct: 470 DSQITTIGNLVPQKTYSVKVLAFT 493



 Score = 28.9 bits (63), Expect = 3.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 123 PRAPGNLTVHTNVSDTLLLTW--SNPYPPDNYLYNHL-TYAVNIWSENDPADFRIYNVTY 179
           P+ PG   V  + + ++ LTW   NP P   Y+  H    +  ++ E D      Y+V  
Sbjct: 320 PKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAG 379

Query: 180 LEP 182
           L P
Sbjct: 380 LSP 382


>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
           precursor [Homo sapiens]
          Length = 1912

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 11/84 (13%)

Query: 118 SEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTY-------AVNIWSENDPA 170
           SE     AP ++      S T+L+ W  P  P+  +  +  Y        VN W +++ A
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472

Query: 171 DFRIYNVTYLEP----SLRIAAST 190
           D +I  +  L P    S+++ A T
Sbjct: 473 DSQITTIGNLVPQKTYSVKVLAFT 496



 Score = 28.9 bits (63), Expect = 3.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 123 PRAPGNLTVHTNVSDTLLLTW--SNPYPPDNYLYNHL-TYAVNIWSENDPADFRIYNVTY 179
           P+ PG   V  + + ++ LTW   NP P   Y+  H    +  ++ E D      Y+V  
Sbjct: 323 PKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAG 382

Query: 180 LEP 182
           L P
Sbjct: 383 LSP 385


>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
           2 precursor [Homo sapiens]
          Length = 1899

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 11/84 (13%)

Query: 118 SEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTY-------AVNIWSENDPA 170
           SE     AP ++      S T+L+ W  P  P+  +  +  Y        VN W +++ A
Sbjct: 400 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 459

Query: 171 DFRIYNVTYLEP----SLRIAAST 190
           D +I  +  L P    S+++ A T
Sbjct: 460 DSQITTIGNLVPQKTYSVKVLAFT 483



 Score = 28.9 bits (63), Expect = 3.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 123 PRAPGNLTVHTNVSDTLLLTW--SNPYPPDNYLYNHL-TYAVNIWSENDPADFRIYNVTY 179
           P+ PG   V  + + ++ LTW   NP P   Y+  H    +  ++ E D      Y+V  
Sbjct: 310 PKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAG 369

Query: 180 LEP 182
           L P
Sbjct: 370 LSP 372


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
           3 precursor [Homo sapiens]
          Length = 1903

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 11/84 (13%)

Query: 118 SEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTY-------AVNIWSENDPA 170
           SE     AP ++      S T+L+ W  P  P+  +  +  Y        VN W +++ A
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472

Query: 171 DFRIYNVTYLEP----SLRIAAST 190
           D +I  +  L P    S+++ A T
Sbjct: 473 DSQITTIGNLVPQKTYSVKVLAFT 496



 Score = 28.9 bits (63), Expect = 3.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 123 PRAPGNLTVHTNVSDTLLLTW--SNPYPPDNYLYNHL-TYAVNIWSENDPADFRIYNVTY 179
           P+ PG   V  + + ++ LTW   NP P   Y+  H    +  ++ E D      Y+V  
Sbjct: 323 PKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAG 382

Query: 180 LEP 182
           L P
Sbjct: 383 LSP 385


>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform
           4 precursor [Homo sapiens]
          Length = 1501

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 11/84 (13%)

Query: 118 SEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTY-------AVNIWSENDPA 170
           SE     AP ++      S T+L+ W  P  P+  +  +  Y        VN W +++ A
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVA 472

Query: 171 DFRIYNVTYLEP----SLRIAAST 190
           D +I  +  L P    S+++ A T
Sbjct: 473 DSQITTIGNLVPQKTYSVKVLAFT 496



 Score = 28.9 bits (63), Expect = 3.8
 Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 123 PRAPGNLTVHTNVSDTLLLTW--SNPYPPDNYLYNHL-TYAVNIWSENDPADFRIYNVTY 179
           P+ PG   V  + + ++ LTW   NP P   Y+  H    +  ++ E D      Y+V  
Sbjct: 323 PKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAG 382

Query: 180 LEP 182
           L P
Sbjct: 383 LSP 385


>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
          Length = 958

 Score = 32.0 bits (71), Expect = 0.45
 Identities = 44/204 (21%), Positives = 77/204 (37%), Gaps = 32/204 (15%)

Query: 33  TCVSD-YMSISTCEWKMNGPTNCS-TELRLLYQLVFL----------LSEAHTCIPENNG 80
           +C +D Y++  TC W  +   + + + L+L Y    L          +SE   C  +++G
Sbjct: 435 SCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDG 494

Query: 81  GAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFK-------PSEHVKPRAPGNLTVHT 133
              C+       +     YT+ +     L   GS         P   VKP  P ++    
Sbjct: 495 FYECI----FQPIFLLSGYTMWIRINHSL---GSLDSPPTCVLPDSVVKPLPPSSVKAEI 547

Query: 134 NVSDTLL-LTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLK 192
            ++  LL ++W  P  P+N L   + Y ++         +++Y V Y   S  ++     
Sbjct: 548 TINIGLLKISWEKPVFPENNLQFQIRYGLS----GKEVQWKMYEV-YDAKSKSVSLPVPD 602

Query: 193 SGISYRARVRAWAQCYNTTWSEWS 216
               Y  +VR         WS WS
Sbjct: 603 LCAVYAVQVRCKRLDGLGYWSNWS 626



 Score = 31.2 bits (69), Expect = 0.76
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 7/103 (6%)

Query: 114 SFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFR 173
           S +P   VKP  P  L +       L ++WS+P      L   + Y+ N  +    AD +
Sbjct: 228 SVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREAD-K 286

Query: 174 IYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWS 216
           I + T L         ++  G SY  +VR         WS+WS
Sbjct: 287 IVSATSL------LVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323


>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
          Length = 896

 Score = 32.0 bits (71), Expect = 0.45
 Identities = 44/204 (21%), Positives = 77/204 (37%), Gaps = 32/204 (15%)

Query: 33  TCVSD-YMSISTCEWKMNGPTNCS-TELRLLYQLVFL----------LSEAHTCIPENNG 80
           +C +D Y++  TC W  +   + + + L+L Y    L          +SE   C  +++G
Sbjct: 435 SCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDG 494

Query: 81  GAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFK-------PSEHVKPRAPGNLTVHT 133
              C+       +     YT+ +     L   GS         P   VKP  P ++    
Sbjct: 495 FYECI----FQPIFLLSGYTMWIRINHSL---GSLDSPPTCVLPDSVVKPLPPSSVKAEI 547

Query: 134 NVSDTLL-LTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLK 192
            ++  LL ++W  P  P+N L   + Y ++         +++Y V Y   S  ++     
Sbjct: 548 TINIGLLKISWEKPVFPENNLQFQIRYGLS----GKEVQWKMYEV-YDAKSKSVSLPVPD 602

Query: 193 SGISYRARVRAWAQCYNTTWSEWS 216
               Y  +VR         WS WS
Sbjct: 603 LCAVYAVQVRCKRLDGLGYWSNWS 626



 Score = 31.2 bits (69), Expect = 0.76
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 7/103 (6%)

Query: 114 SFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFR 173
           S +P   VKP  P  L +       L ++WS+P      L   + Y+ N  +    AD +
Sbjct: 228 SVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREAD-K 286

Query: 174 IYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWS 216
           I + T L         ++  G SY  +VR         WS+WS
Sbjct: 287 IVSATSL------LVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323


>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
          Length = 1165

 Score = 32.0 bits (71), Expect = 0.45
 Identities = 44/204 (21%), Positives = 77/204 (37%), Gaps = 32/204 (15%)

Query: 33  TCVSD-YMSISTCEWKMNGPTNCS-TELRLLYQLVFL----------LSEAHTCIPENNG 80
           +C +D Y++  TC W  +   + + + L+L Y    L          +SE   C  +++G
Sbjct: 435 SCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDG 494

Query: 81  GAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFK-------PSEHVKPRAPGNLTVHT 133
              C+       +     YT+ +     L   GS         P   VKP  P ++    
Sbjct: 495 FYECI----FQPIFLLSGYTMWIRINHSL---GSLDSPPTCVLPDSVVKPLPPSSVKAEI 547

Query: 134 NVSDTLL-LTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLK 192
            ++  LL ++W  P  P+N L   + Y ++         +++Y V Y   S  ++     
Sbjct: 548 TINIGLLKISWEKPVFPENNLQFQIRYGLS----GKEVQWKMYEV-YDAKSKSVSLPVPD 602

Query: 193 SGISYRARVRAWAQCYNTTWSEWS 216
               Y  +VR         WS WS
Sbjct: 603 LCAVYAVQVRCKRLDGLGYWSNWS 626



 Score = 31.2 bits (69), Expect = 0.76
 Identities = 28/103 (27%), Positives = 42/103 (40%), Gaps = 7/103 (6%)

Query: 114 SFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFR 173
           S +P   VKP  P  L +       L ++WS+P      L   + Y+ N  +    AD +
Sbjct: 228 SVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREAD-K 286

Query: 174 IYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWS 216
           I + T L         ++  G SY  +VR         WS+WS
Sbjct: 287 IVSATSL------LVDSILPGSSYEVQVRGKRLDGPGIWSDWS 323


>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
           sapiens]
          Length = 468

 Score = 32.0 bits (71), Expect = 0.45
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 9/109 (8%)

Query: 121 VKPRAPGNLTVHTNVSDT--LLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVT 178
           ++P  P N+TV     +   L +TW +P+  ++  Y  L + +   +E     F  + V 
Sbjct: 214 LQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYR-LRFELRYRAERSKT-FTTWMVK 271

Query: 179 YLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSP---STKWHNS 224
            L+    I  +   SG+ +  ++RA  +     WSEWSP    T W  S
Sbjct: 272 DLQHHCVIHDAW--SGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 318


>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
           sapiens]
          Length = 365

 Score = 32.0 bits (71), Expect = 0.45
 Identities = 29/109 (26%), Positives = 49/109 (44%), Gaps = 9/109 (8%)

Query: 121 VKPRAPGNLTVHTNVSDT--LLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVT 178
           ++P  P N+TV     +   L +TW +P+  ++  Y  L + +   +E     F  + V 
Sbjct: 214 LQPDPPANITVTAVARNPRWLSVTWQDPHSWNSSFYR-LRFELRYRAERSKT-FTTWMVK 271

Query: 179 YLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSP---STKWHNS 224
            L+    I  +   SG+ +  ++RA  +     WSEWSP    T W  S
Sbjct: 272 DLQHHCVIHDAW--SGLRHVVQLRAQEEFGQGEWSEWSPEAMGTPWTES 318


>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
          Length = 1018

 Score = 31.2 bits (69), Expect = 0.76
 Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 34  CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDV 93
           CV+    I T  W  NG      ELR LY + F  +  + CI EN  GA    +  +  +
Sbjct: 352 CVATGKPIPTIRWLKNGYAYHKGELR-LYDVTFENAGMYQCIAENTYGA-IYANAELKIL 409

Query: 94  VSADNYTLDLWAGQQLLWKG-----SFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSN 145
             A  + ++    + L  KG       KP    KP+   +      V+ + +L W +
Sbjct: 410 ALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWED 466


>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
          Length = 1805

 Score = 31.2 bits (69), Expect = 0.76
 Identities = 20/81 (24%), Positives = 32/81 (39%), Gaps = 3/81 (3%)

Query: 123  PRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEP 182
            P APG L       D+L L+W  P  P+  +  +L              FR+   +   P
Sbjct: 1624 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDS---P 1680

Query: 183  SLRIAASTLKSGISYRARVRA 203
              R+    L   + Y+ +V+A
Sbjct: 1681 ESRLTVPGLSENVPYKFKVQA 1701


>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
          Length = 1822

 Score = 31.2 bits (69), Expect = 0.76
 Identities = 20/81 (24%), Positives = 32/81 (39%), Gaps = 3/81 (3%)

Query: 123  PRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEP 182
            P APG L       D+L L+W  P  P+  +  +L              FR+   +   P
Sbjct: 1641 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDS---P 1697

Query: 183  SLRIAASTLKSGISYRARVRA 203
              R+    L   + Y+ +V+A
Sbjct: 1698 ESRLTVPGLSENVPYKFKVQA 1718


>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
          Length = 1752

 Score = 31.2 bits (69), Expect = 0.76
 Identities = 20/81 (24%), Positives = 32/81 (39%), Gaps = 3/81 (3%)

Query: 123  PRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEP 182
            P APG L       D+L L+W  P  P+  +  +L              FR+   +   P
Sbjct: 1571 PSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATAFRVDGDS---P 1627

Query: 183  SLRIAASTLKSGISYRARVRA 203
              R+    L   + Y+ +V+A
Sbjct: 1628 ESRLTVPGLSENVPYKFKVQA 1648


>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
          Length = 1007

 Score = 31.2 bits (69), Expect = 0.76
 Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 34  CVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDV 93
           CV+    I T  W  NG      ELR LY + F  +  + CI EN  GA    +  +  +
Sbjct: 341 CVATGKPIPTIRWLKNGYAYHKGELR-LYDVTFENAGMYQCIAENTYGA-IYANAELKIL 398

Query: 94  VSADNYTLDLWAGQQLLWKG-----SFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSN 145
             A  + ++    + L  KG       KP    KP+   +      V+ + +L W +
Sbjct: 399 ALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWED 455


>gi|28610151 interleukin 7 receptor precursor [Homo sapiens]
          Length = 459

 Score = 30.8 bits (68), Expect = 0.99
 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 5/100 (5%)

Query: 121 VKPRAPGNLTV-HTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTY 179
           VKP AP +L+V +   ++  ++T++  +    Y+   L + V    E D   +   N++ 
Sbjct: 127 VKPEAPFDLSVVYREGANDFVVTFNTSHLQKKYV-KVLMHDVAYRQEKDENKWTHVNLS- 184

Query: 180 LEPSLRIAASTLKSGISYRARVRAWAQCY-NTTWSEWSPS 218
               L +    L+    Y  +VR+    Y    WSEWSPS
Sbjct: 185 -STKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPS 223


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 16/40 (40%), Positives = 21/40 (52%)

Query: 107  QQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNP 146
            Q ++ K   KP +   P   G LTV    SD+LLL W+ P
Sbjct: 1046 QGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVP 1085


>gi|140560917 myomesin 1 isoform b [Homo sapiens]
          Length = 1589

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 6/99 (6%)

Query: 104 WAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNI 163
           W GQ ++ +   +PSE + P  P +L+V       ++L+W    PP    +  + Y V  
Sbjct: 621 WTGQIIVTEE--EPSEGIVPGPPTDLSVTEATRSYVVLSWK---PPGQRGHEGIMYFVE- 674

Query: 164 WSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVR 202
             E    +++  N      S R A   L  G SY  RVR
Sbjct: 675 KCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVR 713


>gi|140560919 myomesin 1 isoform a [Homo sapiens]
          Length = 1685

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 6/99 (6%)

Query: 104 WAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNI 163
           W GQ ++ +   +PSE + P  P +L+V       ++L+W    PP    +  + Y V  
Sbjct: 621 WTGQIIVTEE--EPSEGIVPGPPTDLSVTEATRSYVVLSWK---PPGQRGHEGIMYFVE- 674

Query: 164 WSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVR 202
             E    +++  N      S R A   L  G SY  RVR
Sbjct: 675 KCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVR 713


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,535,108
Number of Sequences: 37866
Number of extensions: 471628
Number of successful extensions: 1160
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 1018
Number of HSP's gapped (non-prelim): 203
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.