Search of human proteins with 55956786

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55956786 spindle assembly associated Sfi1 homolog isoform a
[Homo sapiens]
         (1242 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55956786 spindle assembly associated Sfi1 homolog isoform a [...  2555   0.0  
gi|55956784 spindle assembly associated Sfi1 homolog isoform b [...  2473   0.0  
gi|91208420 bassoon protein [Homo sapiens]                             50   1e-05
gi|24308223 hypothetical protein LOC57577 [Homo sapiens]               49   3e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    49   4e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    48   5e-05
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          47   1e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          47   1e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          47   1e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    46   2e-04
gi|51466800 PREDICTED: hypothetical protein [Homo sapiens]             46   2e-04
gi|169172766 PREDICTED: hypothetical protein LOC389630 [Homo sap...    46   2e-04
gi|148746195 trichohyalin [Homo sapiens]                               46   2e-04
gi|89027871 PREDICTED: hypothetical protein [Homo sapiens]             45   3e-04
gi|89027820 PREDICTED: hypothetical protein [Homo sapiens]             45   3e-04
gi|51466907 PREDICTED: hypothetical protein [Homo sapiens]             45   4e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                45   4e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    45   6e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    45   6e-04
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    44   7e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    44   7e-04
gi|51466802 PREDICTED: hypothetical protein [Homo sapiens]             44   0.001
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        44   0.001
gi|211971097 hypothetical protein LOC441317 [Homo sapiens]             44   0.001
gi|169173146 PREDICTED: hypothetical protein [Homo sapiens]            44   0.001
gi|239742272 PREDICTED: hypothetical protein XP_002342469 isofor...    44   0.001
gi|239742270 PREDICTED: hypothetical protein XP_002342468 isofor...    44   0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    43   0.002
gi|51466913 PREDICTED: hypothetical protein [Homo sapiens]             43   0.002
gi|113419951 PREDICTED: hypothetical protein [Homo sapiens]            43   0.002

>gi|55956786 spindle assembly associated Sfi1 homolog isoform a [Homo
            sapiens]
          Length = 1242

 Score = 2555 bits (6622), Expect = 0.0
 Identities = 1242/1242 (100%), Positives = 1242/1242 (100%)

Query: 1    MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60
            MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
Sbjct: 1    MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60

Query: 61   ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120
            ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
Sbjct: 61   ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120

Query: 121  LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180
            LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
Sbjct: 121  LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180

Query: 181  HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240
            HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
Sbjct: 181  HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240

Query: 241  HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300
            HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
Sbjct: 241  HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300

Query: 301  RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360
            RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
Sbjct: 301  RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360

Query: 361  HYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHR 420
            HYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHR
Sbjct: 361  HYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHR 420

Query: 421  FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH 480
            FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH
Sbjct: 421  FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH 480

Query: 481  FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE 540
            FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE
Sbjct: 481  FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE 540

Query: 541  RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR 600
            RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR
Sbjct: 541  RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR 600

Query: 601  TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT 660
            TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT
Sbjct: 601  TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT 660

Query: 661  YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV 720
            YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV
Sbjct: 661  YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV 720

Query: 721  LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ 780
            LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ
Sbjct: 721  LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ 780

Query: 781  HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA 840
            HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA
Sbjct: 781  HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA 840

Query: 841  TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM 900
            TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM
Sbjct: 841  TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM 900

Query: 901  KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL 960
            KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL
Sbjct: 901  KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL 960

Query: 961  NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ 1020
            NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ
Sbjct: 961  NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ 1020

Query: 1021 SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP 1080
            SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP
Sbjct: 1021 SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP 1080

Query: 1081 ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG 1140
            ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG
Sbjct: 1081 ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG 1140

Query: 1141 LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ 1200
            LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ
Sbjct: 1141 LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ 1200

Query: 1201 QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC 1242
            QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
Sbjct: 1201 QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC 1242


>gi|55956784 spindle assembly associated Sfi1 homolog isoform b [Homo
            sapiens]
          Length = 1211

 Score = 2473 bits (6410), Expect = 0.0
 Identities = 1211/1242 (97%), Positives = 1211/1242 (97%), Gaps = 31/1242 (2%)

Query: 1    MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60
            MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
Sbjct: 1    MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60

Query: 61   ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120
            ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
Sbjct: 61   ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120

Query: 121  LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180
            LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
Sbjct: 121  LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180

Query: 181  HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240
            HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
Sbjct: 181  HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240

Query: 241  HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300
            HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
Sbjct: 241  HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300

Query: 301  RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360
            RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
Sbjct: 301  RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360

Query: 361  HYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHR 420
            HYMLLCAEEAAQFEMAEEHHRHSQL                               LLHR
Sbjct: 361  HYMLLCAEEAAQFEMAEEHHRHSQL-------------------------------LLHR 389

Query: 421  FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH 480
            FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH
Sbjct: 390  FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH 449

Query: 481  FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE 540
            FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE
Sbjct: 450  FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE 509

Query: 541  RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR 600
            RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR
Sbjct: 510  RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR 569

Query: 601  TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT 660
            TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT
Sbjct: 570  TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT 629

Query: 661  YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV 720
            YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV
Sbjct: 630  YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV 689

Query: 721  LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ 780
            LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ
Sbjct: 690  LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ 749

Query: 781  HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA 840
            HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA
Sbjct: 750  HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA 809

Query: 841  TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM 900
            TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM
Sbjct: 810  TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM 869

Query: 901  KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL 960
            KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL
Sbjct: 870  KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL 929

Query: 961  NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ 1020
            NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ
Sbjct: 930  NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ 989

Query: 1021 SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP 1080
            SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP
Sbjct: 990  SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP 1049

Query: 1081 ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG 1140
            ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG
Sbjct: 1050 ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG 1109

Query: 1141 LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ 1200
            LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ
Sbjct: 1110 LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ 1169

Query: 1201 QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC 1242
            QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
Sbjct: 1170 QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC 1211


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 65/239 (27%), Positives = 98/239 (41%), Gaps = 38/239 (15%)

Query: 1011 RPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTR-PFLAEAPTALVPHSPL-PGALSSAP 1068
            +P  +L P       +P   G G+      SLTR P +A       P  PL P  L   P
Sbjct: 2211 QPASVLRPMVRGGMYRPYASG-GITAVPLTSLTRVPMIA-------PRVPLGPTGLYRYP 2262

Query: 1069 GPKQPPTAST-----GPELLLLPLSSFMPCGAAAPARVSAQRATPRDKP----------- 1112
             P + P AS+     GP  L  P ++  P GA  P+R        R++P           
Sbjct: 2263 APSRFPIASSVPPAEGPVYLGKPAAAKAP-GAGGPSRPEMPVGAAREEPLPTTTPAAIKE 2321

Query: 1113 ----PVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQ 1168
                P P+ LA    P    PG  S   + PG     +   E + ++ Q+QLL  +  + 
Sbjct: 2322 AAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEERQRKQ-QEQLLQLERERV 2380

Query: 1169 NLWSCRRQASSLRRWLELNREEPGPEDQEVEQQ--VQKELEQVEMQIQLLAEELQAQRQ 1225
             L   R+    LR   EL RE    +    E+Q  VQ+EL++++     + ++ Q +RQ
Sbjct: 2381 ELEKLRQ----LRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQ 2435



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 17/150 (11%)

Query: 965  AGAGDGTLETK-RPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQR 1023
            A +G   L++K  PQA   L   GR AA  P   + + + S+R+ P         A S++
Sbjct: 3728 AHSGPAALQSKAEPQAQPQLQ--GRQAAPGP---QQSQSPSSRQIP-------SGAASRQ 3775

Query: 1024 PQ-KPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGPEL 1082
            PQ + Q+ GLG+ QP   +LT+  L +        S  P A   A  P+  P+ +TGP+ 
Sbjct: 3776 PQTQQQQQGLGL-QPPQQALTQARLQQQSQPTTRGSA-PAASQPAGKPQPGPSTATGPQP 3833

Query: 1083 LLLPLSSFMPCGAAAPARVSAQRATPRDKP 1112
               P +     G+   A+   Q   P+ +P
Sbjct: 3834 AGPPRAE-QTNGSKGTAKAPQQGRAPQAQP 3862



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 37/118 (31%), Positives = 47/118 (39%), Gaps = 17/118 (14%)

Query: 992  EEPHALELNTAHSARKQPRRPHFLLEPAQ--SQRPQKPQEHGLGMAQPAAPSLTRPFLAE 1049
            ++ H+  L+ AHS  KQP     L +P Q  S+ P  PQ          A S+  P  A 
Sbjct: 240  QQLHSPALSPAHSPAKQP-----LGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAA 294

Query: 1050 APTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRAT 1107
            AP  +   SP P      P P +P TA   P     P  S      A PA + A   T
Sbjct: 295  APPEVGRVSPQP------PQPTKPSTAEPRPPAGEAPAKS----ATAVPAGLGATEQT 342



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 13/121 (10%)

Query: 967  AGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPH-FLLEPAQSQRPQ 1025
            A  G+     PQA   L A GR A E+P  L  +       QP R + +    +    P 
Sbjct: 1426 ANYGSQTEDLPQAPSGLAAAGRAAREKP--LSASDGEGGTPQPSRAYSYFASSSPPLSPS 1483

Query: 1026 KPQEHGLGMAQPAAPSLTRPFLAE----APTALVPHSPLPGALSSAP----GPKQPPTAS 1077
             P E          P  T  F  +    AP + +P S  PGA + +P    G + P   S
Sbjct: 1484 SPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRS--PGAPTPSPMVAQGTQTPHRPS 1541

Query: 1078 T 1078
            T
Sbjct: 1542 T 1542


>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
          Length = 936

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 63/281 (22%), Positives = 120/281 (42%), Gaps = 19/281 (6%)

Query: 21  KQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQ 80
           KQ M      +  ++ A+++    + L+ KK         +L +     Q R       Q
Sbjct: 649 KQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQ 708

Query: 81  GRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKV-FEEWKEEWWVFQHEW 139
              +    R    K L    R+   +   + A+ +YE+ LLRK   E WK      Q + 
Sbjct: 709 LERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR--LRMQSKQ 766

Query: 140 KLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVV 199
            + V A+ HY  +L      TW  + R Q+ +  K  +A+   ++  +++  +SWL YV+
Sbjct: 767 NIQV-AEEHYSLFLQRKYMLTW--FQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVI 823

Query: 200 VRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRV-SRALHASALKHRALSLQVQAWS 258
               + +++   + F Q+ I R W++  R    +V++ S+  H  A +H    +      
Sbjct: 824 --DLQEEVRKFCVHFLQKKIFRAWFNMVR----EVKIDSQGKHEIAAEHSDRRILWITLR 877

Query: 259 QWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQV 299
            W++ + ++++E+      VK  +  Q RR +   L   QV
Sbjct: 878 TWKKFVKFMKEER------VKEERRQQLRRKVVEILPDFQV 912



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 52/238 (21%), Positives = 98/238 (41%), Gaps = 24/238 (10%)

Query: 246 KHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQ-------HWQKRRFLKAWLEYLQ 298
           K  A   + Q   +  E+ L   KE +K     ++ Q       H+++    K  LE  +
Sbjct: 699 KREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWK 758

Query: 299 VRRVKRQQN-EMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFT 357
             R++ +QN ++AE  + + + + Y   W Q    +ESL    AQ ++   ++ L+R   
Sbjct: 759 RLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ--RSQESLARKMAQADQFYSQILLKRVIQ 816

Query: 358 HWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHL-QQIRRNLAHQQHGVT 416
            W  Y++   EE  +F +   H    ++   FRA  + V    +  Q +  +A +     
Sbjct: 817 SWLQYVIDLQEEVRKFCV---HFLQKKI---FRAWFNMVREVKIDSQGKHEIAAEHSDRR 870

Query: 417 LLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQ 474
           +L      W+  ++  KE  +        +  R  L  K +E+   +    RY +L Q
Sbjct: 871 ILWITLRTWKKFVKFMKEERVK-------EERRQQLRRKVVEILPDFQVPGRYHELYQ 921



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 39/171 (22%), Positives = 75/171 (43%), Gaps = 16/171 (9%)

Query: 766 RRSAQQRLQLERAVQHHHRQLLL--EGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTC 823
           ++  ++  QLE   + H+ ++LL  +GL  WK   +Q  +   +  +   L  QR     
Sbjct: 727 QKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLT 786

Query: 824 FRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQG 883
           + Q  Q+  AR+  Q     A  F++  L  +V  +WL +V++       LQ  ++ +  
Sbjct: 787 WFQRSQESLARKMAQ-----ADQFYSQILLKRVIQSWLQYVID-------LQEEVRKFCV 834

Query: 884 QLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKV 934
             LQ+   R   +   ++  +   Q + ++ A HS  R +      WK+ V
Sbjct: 835 HFLQKKIFR--AWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFV 883



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 50/214 (23%), Positives = 88/214 (41%), Gaps = 23/214 (10%)

Query: 532 QHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRL-KKAFC 590
           Q RE    E       E + L +   +  Q+   R+Q+ E   +A  H+    L KK   
Sbjct: 698 QKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLE--AIAKEHYERVLLRKKGLE 755

Query: 591 LWRESAQGLRTERTGRVRAAEFHMAQLLR----WAWSQW-RECLALRGAERQKLMRADLH 645
            W+     LR +    ++ AE H +  L+      W Q  +E LA      +K+ +AD  
Sbjct: 756 PWKR----LRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLA------RKMAQADQF 805

Query: 646 HQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKT 705
           +   +L R +Q+W+ Y   ++  +R+      Q  +++ R      +E    ++D   K 
Sbjct: 806 YSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQ--KKIFRAWFNMVRE---VKIDSQGKH 860

Query: 706 FQASTHYRRTICSKVLVQWREAVSVQMYYRQQED 739
             A+ H  R I    L  W++ V      R +E+
Sbjct: 861 EIAAEHSDRRILWITLRTWKKFVKFMKEERVKEE 894



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 43/212 (20%), Positives = 85/212 (40%), Gaps = 26/212 (12%)

Query: 368 EEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRS 427
           E+ AQ E   E  R  ++    + L+        QQ+          V L  +    W+ 
Sbjct: 704 EKEAQLERKREEKRLKKM----KELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR 759

Query: 428 QIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALP 487
              Q K+      +  A +HY + L  K +  W Q +Q+   +++  A+AD  + Q  L 
Sbjct: 760 LRMQSKQN-----IQVAEEHYSLFLQRKYMLTWFQRSQESLARKM--AQADQFYSQILLK 812

Query: 488 AAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHR-ENRLAERMAILH 546
               +      W      L     +F    L+K++F  W   + + + +++    +A  H
Sbjct: 813 RVIQS------WLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEH 866

Query: 547 AERQLLY---RSW-----FMWHQQAAARHQEQ 570
           ++R++L+   R+W     FM  ++     ++Q
Sbjct: 867 SDRRILWITLRTWKKFVKFMKEERVKEERRQQ 898


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
            tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 1/124 (0%)

Query: 1017 EPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTA 1076
            +P   Q P  PQ H      P     ++P +A+ P         P A SSAP P  PPT+
Sbjct: 81   QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP-PATPPTS 139

Query: 1077 STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATR 1136
               P     P  +  P   +AP             P  P      P P   +PG     +
Sbjct: 140  GAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPK 199

Query: 1137 AGPG 1140
             GPG
Sbjct: 200  QGPG 203



 Score = 33.9 bits (76), Expect = 0.99
 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 5/90 (5%)

Query: 759 QRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS-----TQ 813
           QRW        QQR Q+E+ ++    +L  E    +  H    +R+ L+ RQ       +
Sbjct: 492 QRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEE 551

Query: 814 LLAQRLSRTCFRQWRQQLAARRQEQRATVR 843
           L  Q + +    Q RQ+   RR+E+   +R
Sbjct: 552 LHNQEMQKRKEMQLRQEEERRRREEEMMIR 581


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 23/190 (12%)

Query: 939  GKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALE 998
            G P+P  +  P  +   EGP   +  + A + +     P A R   A G L  + P +  
Sbjct: 179  GLPRPAPSARP--RPPTEGP--RKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRS 232

Query: 999  LNTAHSARKQPRR--PHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVP 1056
            L+++ +    P R  P     P     P +P+  GL   +P  P +T P    AP     
Sbjct: 233  LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP--PQVTPPRKDAAPAL--- 287

Query: 1057 HSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPS 1116
              PL  +  + P P  PP+ S  P L  LP         + PA   +Q  T    P + +
Sbjct: 288  -GPLSSSPLATPSPSAPPSPSAPPSLQTLP---------SPPATPPSQATTSLGSPTLQA 337

Query: 1117 SLASVPDPHL 1126
            + + +P P L
Sbjct: 338  THSFLPSPPL 347



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 46/157 (29%), Positives = 60/157 (38%), Gaps = 13/157 (8%)

Query: 977  PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQ 1036
            P AS PL  L   + + P+AL ++   +    P  P     P Q+  P  P         
Sbjct: 372  PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQA--PFSPPASPPVSPS 424

Query: 1037 PAAPSLTRPFLAEAPTALVPHSPL--PGALSSAPGPKQPPTASTGPELLLLPLSSFMPCG 1094
               PS   P LA  P  + P  P   P + S+ P P+ PP  +  P  L  P     P  
Sbjct: 425  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484

Query: 1095 AAAP--ARVSAQRATPRDKPPVPSSLASVPDPHLLLP 1129
            A  P  A  S   + P   P  PS  AS+P   L  P
Sbjct: 485  ATPPLQALPSPPASFPGQAPFSPS--ASLPMSPLATP 519



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 8/119 (6%)

Query: 1012 PHFLLEPAQS--QRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPG 1069
            P   L P Q+    P  P    L    P AP+     L +AP +  P  P+    S    
Sbjct: 359  PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418

Query: 1070 PKQPPTA---STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPV---PSSLASVP 1122
            P   P+A   S  P  L  P     P   A+P    +    P+  PP+   P  LA  P
Sbjct: 419  PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 51/217 (23%), Positives = 66/217 (30%), Gaps = 45/217 (20%)

Query: 977  PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEH------ 1030
            P AS P+        + P  L       A+  P+ P  L  P     P  P         
Sbjct: 446  PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505

Query: 1031 ----GLGMAQPAAPSLTRPFLAEAPTALVPHSP-------------LPG----------A 1063
                 L M+  A P    P +  AP   VP SP              PG           
Sbjct: 506  SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 565

Query: 1064 LSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRD----KPPVPSSLA 1119
            L+ APGP  PP+ S    L    L+       + P  +    + P       PP  + LA
Sbjct: 566  LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 625

Query: 1120 SV--------PDPHLLLPGDFSATRAGPGLSTAGSLD 1148
            +         P P L   G   A    P  +  GS D
Sbjct: 626  ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 56/209 (26%), Positives = 80/209 (38%), Gaps = 30/209 (14%)

Query: 948  APSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALG-RLAAEEPHALELNT----- 1001
            AP  K T  GP+ +    G   GT    RP    PLG  G R++AEE  A    T     
Sbjct: 94   APPAKNTSPGPVSS---PGRASGTT---RPG---PLGQKGLRISAEETVARGKATEAPKR 144

Query: 1002 ---AHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHS 1058
               +  AR+    P          R  +     +G+ +PA  +  RP   E P   V  +
Sbjct: 145  SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPRKSVSSA 203

Query: 1059 PLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGA---AAPARVS-AQRATPR----D 1110
                    +P  ++ P+A  G   L  P S  +   A   ++PAR   + R TPR     
Sbjct: 204  SEHSTTEPSPAARRRPSAGGG---LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 260

Query: 1111 KPPVPSSLASVPDPHLLLPGDFSATRAGP 1139
              P P  L ++  P +  P   +A   GP
Sbjct: 261  SQPKPKGLQALRPPQVTPPRKDAAPALGP 289


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 66/236 (27%), Positives = 90/236 (38%), Gaps = 38/236 (16%)

Query: 938  GGKPQPLAAIAPSRKVTFEGPLLNRIAA---GAGDGTLETKRPQASRPLGALGRLAAEEP 994
            G  P P +A   + ++   GP  +  A    G+   +    +PQA           A  P
Sbjct: 192  GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP---------TAPVP 242

Query: 995  HALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-QPAAPSLTRPFL-AEAPT 1052
            H           ++P  PH    P     P  P +   G A QP+APS  +P L  + P 
Sbjct: 243  HTHIQQAPALHPQRPPSPH----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298

Query: 1053 ALVPHSPLPGALSSAPGPKQ----PPTASTGPELL-LLPLSSFMPCGAAAPARVSA--QR 1105
               PHS   G L   PGP Q    PP AS G   L   P +++       PA  SA   +
Sbjct: 299  G--PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356

Query: 1106 ATPRDKPPVPSSLA--------SVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAEL 1153
              PR++P  P+ LA        + P P L  P    A +  P LS      + A L
Sbjct: 357  QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP---QAHKHPPHLSGPSPFSMNANL 409


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 66/236 (27%), Positives = 90/236 (38%), Gaps = 38/236 (16%)

Query: 938  GGKPQPLAAIAPSRKVTFEGPLLNRIAA---GAGDGTLETKRPQASRPLGALGRLAAEEP 994
            G  P P +A   + ++   GP  +  A    G+   +    +PQA           A  P
Sbjct: 746  GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP---------TAPVP 796

Query: 995  HALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-QPAAPSLTRPFL-AEAPT 1052
            H           ++P  PH    P     P  P +   G A QP+APS  +P L  + P 
Sbjct: 797  HTHIQQAPALHPQRPPSPH----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852

Query: 1053 ALVPHSPLPGALSSAPGPKQ----PPTASTGPELL-LLPLSSFMPCGAAAPARVSA--QR 1105
               PHS   G L   PGP Q    PP AS G   L   P +++       PA  SA   +
Sbjct: 853  G--PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910

Query: 1106 ATPRDKPPVPSSLA--------SVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAEL 1153
              PR++P  P+ LA        + P P L  P    A +  P LS      + A L
Sbjct: 911  QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP---QAHKHPPHLSGPSPFSMNANL 963


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 66/236 (27%), Positives = 90/236 (38%), Gaps = 38/236 (16%)

Query: 938  GGKPQPLAAIAPSRKVTFEGPLLNRIAA---GAGDGTLETKRPQASRPLGALGRLAAEEP 994
            G  P P +A   + ++   GP  +  A    G+   +    +PQA           A  P
Sbjct: 746  GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP---------TAPVP 796

Query: 995  HALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-QPAAPSLTRPFL-AEAPT 1052
            H           ++P  PH    P     P  P +   G A QP+APS  +P L  + P 
Sbjct: 797  HTHIQQAPALHPQRPPSPH----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852

Query: 1053 ALVPHSPLPGALSSAPGPKQ----PPTASTGPELL-LLPLSSFMPCGAAAPARVSA--QR 1105
               PHS   G L   PGP Q    PP AS G   L   P +++       PA  SA   +
Sbjct: 853  G--PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910

Query: 1106 ATPRDKPPVPSSLA--------SVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAEL 1153
              PR++P  P+ LA        + P P L  P    A +  P LS      + A L
Sbjct: 911  QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP---QAHKHPPHLSGPSPFSMNANL 963


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 64/349 (18%), Positives = 132/349 (37%), Gaps = 43/349 (12%)

Query: 499 WRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFM 558
           WR +E +      R   E + +Q   +WRQ+   H + ++ E       E         M
Sbjct: 433 WRQEEKI------REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE--------M 478

Query: 559 WHQQAAARHQEQEWQTVACAHHRHGRLKKAF-CLWRESAQGLRTERTGRVRAAEFHM--- 614
           W Q+     QE+ W+     H +  +++K    +WR+  +    E+  ++R  E  M   
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK--IREQEEKIREQEEKMWRQ 536

Query: 615 AQLLRWAWSQWRECLALRGAERQKLMRADLHH-QHSVLHRALQAWVTYQGRVRSILREVA 673
            + +R     WRE   +   E++K+   +    Q   + R  +     + +V    +E  
Sbjct: 537 EEKIREQEEMWREEEKMH--EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR--QEEK 592

Query: 674 ARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMY 733
            RE +  RQ      + WK+    R  E K   Q      R    K+  Q       +  
Sbjct: 593 IREQEEKRQ--EQEEKMWKQEEKIREQEEK--IQEQEEKIREQEEKIREQEEMTQEQEEK 648

Query: 734 YRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQL---ERAVQHHHRQLLLEG 790
             +QE+    + +K+ ++       +  W    +  +Q  ++   E  ++     +  + 
Sbjct: 649 MGEQEEKMCEQEEKMQEQE------ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQE 702

Query: 791 LARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQR 839
              W+     C ++  +  Q      +++ R   + W Q++  R+QE++
Sbjct: 703 EKMWEQEEKMCEQEEKMQEQE-----EKMRRQEEKMWEQEVRLRQQEEK 746



 Score = 35.0 bits (79), Expect = 0.45
 Identities = 70/441 (15%), Positives = 168/441 (38%), Gaps = 61/441 (13%)

Query: 502 QENVLSARATRFHRETLEKQVFSL--WRQKMFQHRENRLAERMAILHAERQLLYRSWFMW 559
           +EN L  R  +   E + +Q   +  W +K+ +  E    +   I   E ++  +   MW
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345

Query: 560 HQQAAARHQEQ-EWQTVACAHHRHGRL-KKAFCLWRESAQGLRTERTGRVRAAEFHMAQL 617
            ++   R QE+  W+       +   + +K   + R+       E   R    + H  + 
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405

Query: 618 LRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARES 677
           +R    + +E   +R  E+++   A +  Q   +          + ++R   +++  +E 
Sbjct: 406 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-------QEEKIREQEKKMWRQEE 458

Query: 678 Q-HNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSV---QMY 733
           + H ++ +R   +R ++  M R +E         H +  I       WR+   +   +  
Sbjct: 459 KIHEQEKIREEEKRQEQEEMWRQEE-------KIHEQEEI-------WRQKEKMHEQEEK 504

Query: 734 YRQQEDCAIWEAQKVLDR-GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLA 792
            R+QE+    + +K+ ++   +R   ++ W    +  +Q        + H ++ + E   
Sbjct: 505 IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK 564

Query: 793 RWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSL 852
           R +       ++  +  Q  ++            WRQ+   R QE++   +         
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKV------------WRQEEKIREQEEKRQEQ--------- 603

Query: 853 QAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQ 912
           + K+W         ++ +K R Q      Q + ++E   + +R    M   +++   +Q+
Sbjct: 604 EEKMW---------KQEEKIREQEEKIQEQEEKIREQEEK-IREQEEMTQEQEEKMGEQE 653

Query: 913 VQAAHSLHRAVRRCATLWKQK 933
            +      +   +  T+W+Q+
Sbjct: 654 EKMCEQEEKMQEQEETMWRQE 674


>gi|51466800 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 62/241 (25%), Positives = 86/241 (35%), Gaps = 44/241 (18%)

Query: 917  HSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----GPLLNRIAAGA---- 967
            H+  +  R    L  +      G+   LA+++P RK +       GP   +  A A    
Sbjct: 153  HTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQ 212

Query: 968  ------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSARKQPRRPHFLLEPA 1019
                  G   L   +P  SRP G    +  AA + H L    A   + Q +RP    +P 
Sbjct: 213  PAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLL--QAARPQAQDKRPAVTSQPC 270

Query: 1020 QSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL------------VPHSPLPGALSSA 1067
                P      GLG      P   RP  A     L            +P S + G    A
Sbjct: 271  P---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGA 327

Query: 1068 PGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRDKPPVPSSLASVPDP 1124
            P   QPP A+T  GP       S+    G   PA+V S  R  P  +P +P++ A     
Sbjct: 328  PENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSH 380

Query: 1125 H 1125
            H
Sbjct: 381  H 381


>gi|169172766 PREDICTED: hypothetical protein LOC389630 [Homo sapiens]
          Length = 464

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 62/241 (25%), Positives = 86/241 (35%), Gaps = 44/241 (18%)

Query: 917  HSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----GPLLNRIAAGA---- 967
            H+  +  R    L  +      G+   LA+++P RK +       GP   +  A A    
Sbjct: 153  HTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQ 212

Query: 968  ------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSARKQPRRPHFLLEPA 1019
                  G   L   +P  SRP G    +  AA + H L    A   + Q +RP    +P 
Sbjct: 213  PAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLL--QAARPQAQDKRPAVTSQPC 270

Query: 1020 QSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL------------VPHSPLPGALSSA 1067
                P      GLG      P   RP  A     L            +P S + G    A
Sbjct: 271  P---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGA 327

Query: 1068 PGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRDKPPVPSSLASVPDP 1124
            P   QPP A+T  GP       S+    G   PA+V S  R  P  +P +P++ A     
Sbjct: 328  PENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSH 380

Query: 1125 H 1125
            H
Sbjct: 381  H 381


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 114/539 (21%), Positives = 203/539 (37%), Gaps = 84/539 (15%)

Query: 327  QQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLY 386
            ++ W++R+  +    Q+E+  +K A RR     +   LL  E        EE  R  +  
Sbjct: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER-------EEKRRRQETD 1335

Query: 387  FCFRALKDNVTHAHLQQIRR----------NLAHQQHGVTLLHRFWNLWRSQIEQKKERE 436
              FR  +  +     Q +RR           L HQ+ G   L     L R + E+K  +E
Sbjct: 1336 RKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE 1395

Query: 437  LLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYK----QLLQARADGHFQQRALPAAFHT 492
                           L C+  E  L+  + R+++    QL +   D  F++         
Sbjct: 1396 ------------EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE 1443

Query: 493  WNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENR----LAERMAILHAE 548
              R +    Q+     R  R HR+  E++     R++   HR+ R    L E   +   E
Sbjct: 1444 RERKFLEEEQQ----LRQER-HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE 1498

Query: 549  RQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVR 608
            R   +R   +  Q+   +  E+E Q      HR  R +K    + +  Q LR +  G+ R
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQL-----HRQQRQRK----FLQEEQQLRRQERGQQR 1549

Query: 609  AAE----FHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGR 664
              +    F   + LR    Q RE   L   ER +  R +            +  V  Q +
Sbjct: 1550 RQDRDRKFREEEQLR----QEREEQQLSRQERDRKFRLE------------EQKVRRQEQ 1593

Query: 665  VRSILR-EVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQ 723
             R  +  E   R  +  +QL +   R+++E+     +  ++        R+ +  +  ++
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653

Query: 724  WREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRL---QLERAVQ 780
             +E    +   R   D    E +++L  G  +   ++  D   R  +Q+L   + ER   
Sbjct: 1654 RQER---EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710

Query: 781  HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQR 839
               +QL  + L R K    + +R+     +  QL  Q   R    +  +QL   R+EQ+
Sbjct: 1711 QEEQQLRRQELER-KFREEEQLRQ---ETEQEQLRRQERYRKILEE--EQLRPEREEQQ 1763



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 163/776 (21%), Positives = 280/776 (36%), Gaps = 127/776 (16%)

Query: 279  KHHQHWQKRRFLKAWLEYLQ-VRRVKRQQNEMAERFHHVTVLQIYFCD----WQQAWERR 333
            +  Q WQ+R   +A  E LQ  +  + ++    E+     +L++         QQ  ER+
Sbjct: 175  RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ 234

Query: 334  ESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALK 393
            + ++    + E   R+  LR+     +   L   E   Q E+ EE  +  +L        
Sbjct: 235  DRVFQEEEEKEWRKRETVLRK-----EEEKLQEEEPQRQRELQEEEEQLRKL-------- 281

Query: 394  DNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALL 453
                    Q++RR    ++     L R   L R Q E+++E++            R    
Sbjct: 282  ------ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE----ERREQQERREQQ 331

Query: 454  CKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRF 513
             +  E  L+  Q+ R +Q L+   +   +++ L        R  + R ++ +   R  + 
Sbjct: 332  EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL--RREQQL 389

Query: 514  HRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQ 573
             RE   ++   L R++  +  +    E+   L  E+QL         +Q   RH+++  Q
Sbjct: 390  RREQQLRREQQLRREQQLRREQQLRREQQ--LRREQQLR-------REQEEERHEQKHEQ 440

Query: 574  TVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRE-CLALR 632
                   R  RLK+      E    L+ E        E    QL R    + RE  L L 
Sbjct: 441  -----ERREQRLKRE---QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492

Query: 633  GAER--------QKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLL 684
              ER        Q+L R     +   L R  +     Q R+RS   +   RE +  R+ L
Sbjct: 493  EEERREQQERREQQLRREQEERREQRLKRQEEE-ERLQQRLRS--EQQLRREQEERREQL 549

Query: 685  RGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWE 744
               L+R +E  + + +  ++  +     RR      L++  E    Q   R+QE+     
Sbjct: 550  ---LKREEEKRLEQ-ERREQRLKREQEERRD----QLLKREEERRQQRLKREQEER---- 597

Query: 745  AQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRK 804
                L++   R   +R     RR  +QRL+ E   +   RQ LL+   + +    Q  R+
Sbjct: 598  ----LEQRLKREEVERLEQEERR--EQRLKREEP-EEERRQQLLKSEEQEERRQQQLRRE 650

Query: 805  -------RLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVW 857
                   RL   +  + L QRL R    + R+Q  A  ++++A  R         +   W
Sbjct: 651  QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER------IKSRIPKW 704

Query: 858  ATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAH 917
               L    + R+ K         Y     QEG  R        +    +LQ Q++ +A  
Sbjct: 705  QWQLESEADARQSK--------VYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHR 756

Query: 918  SLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRP 977
                  +R    W+ +   +  + +   +  P        PL                R 
Sbjct: 757  QQQEEEQRRDFTWQWQAEEKSERGRQRLSARP--------PL----------------RE 792

Query: 978  QASRPLGALGRLAAEEPHALELNTAHSARKQPRRP----HFLLEPAQSQRPQKPQE 1029
            Q  R L A  R   E+    E       R+Q R       FL E  Q QR ++ Q+
Sbjct: 793  QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 121/586 (20%), Positives = 213/586 (36%), Gaps = 78/586 (13%)

Query: 85   ELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKVFEEWKE------EWWVFQHE 138
            E ++RC  R+     +R    R F  + +    Q   RK  EE ++      E    + E
Sbjct: 1396 EQQLRCQERE---QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452

Query: 139  WKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYV 198
             +L  R + H ++     + Q  +     +QE   K++  E    +Q+  + ++   +  
Sbjct: 1453 QQL--RQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRS 1510

Query: 199  VVRRTKLQMQTTAL--EFRQRIILRVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQA 256
                 K   +   L  + RQR  L+      RQ  GQ R          + R    + Q 
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD-------RDRKFREEEQL 1563

Query: 257  WSQWREQLLYVQKEKQKV-VSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHH 315
              +  EQ L  Q+  +K  +   K  +  Q+R+F++   +  Q+RR + QQ    ER   
Sbjct: 1564 RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME---DEQQLRRQEGQQQLRQERDRK 1620

Query: 316  VTVLQIYFCDWQQAWERRESLYAHHAQVEK--LARKMALRRAFTHWKHYMLLCAEEAAQF 373
                   F + +Q  + RE    H  + ++  L  +  LRR     +    L  +   +F
Sbjct: 1621 -------FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ----EREQQLRHDRDRKF 1669

Query: 374  EMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKK 433
               E+  +  +     R  +D       QQ+RR    Q+     L     L R ++E+K 
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRR----QERERKFLQEEQQLRRQELERKF 1725

Query: 434  ERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTW 493
              E         +  R     + +    +Y +    +QL   R +   +++     F   
Sbjct: 1726 REE---------EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776

Query: 494  NRLWRWRHQENVLSARATRFHRETL-------EKQVFSLWRQKMFQHRENRLA--ERMAI 544
             +L + R ++ + S  + R  RE         E+Q+    R   ++  E +L   E+   
Sbjct: 1777 EQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQR 1836

Query: 545  LHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLRTERT 604
            L  ER   YR+   +  Q  +R +EQE                   LW+E  Q  R ER 
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQE-------------------LWQEEEQKRRQERE 1877

Query: 605  GRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSV 650
             ++R       Q       Q  E  +  G    +L+    H   SV
Sbjct: 1878 RKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASV 1923



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 137/695 (19%), Positives = 254/695 (36%), Gaps = 123/695 (17%)

Query: 261  REQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNE--MAERFHHVTV 318
            RE+ L +++E+++        Q  ++ + L+   E  + +R+KRQ+ E  + +R      
Sbjct: 485  RERWLKLEEEERR-------EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537

Query: 319  LQIYFCDWQQAWERRESLYAHHAQ--VEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMA 376
            L+      ++  ERRE L     +  +E+  R+  L+R     +  +L   EE  Q  + 
Sbjct: 538  LR------REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591

Query: 377  EEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERE 436
             E     +     R  ++ V     ++ R     ++       R   L +S  E+++ER 
Sbjct: 592  REQEERLEQ----RLKREEVERLEQEERREQRLKREEPEE--ERRQQLLKS--EEQEERR 643

Query: 437  LLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRL 496
               L     +     L  +  E  L+   KR +++  + +     +Q        +    
Sbjct: 644  QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703

Query: 497  WRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSW 556
            W+W+ +             +  + +V+S  R++  Q R     E+     +E Q      
Sbjct: 704  WQWQLESEA----------DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ------ 747

Query: 557  FMWHQQAAARHQEQE--------WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVR 608
              W ++  A  Q+QE        WQ  A      GR + +      +   LR +R  ++R
Sbjct: 748  --WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS------ARPPLREQRERQLR 799

Query: 609  AAEFHMAQLLRWAWSQWRECLALRGAERQK-LMRADLHHQHSVLHRALQAWVTYQGRVRS 667
            A E    +       + +E    +  ER+K L   +   Q     RA Q      G    
Sbjct: 800  AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG---- 855

Query: 668  ILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREA 727
            +  +   R SQ  R   R    RW+      ++E +K        R T+ +K  +Q +  
Sbjct: 856  LQEDQERRRSQEQR---RDQKWRWQ------LEEERK------RRRHTLYAKPALQEQLR 900

Query: 728  VSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQR-LQLERAVQHHHRQL 786
               Q+   ++E+    E +K                  RR  Q+R  + E  +Q    QL
Sbjct: 901  KEQQLLQEEEEELQREEREK-----------------RRRQEQERQYREEEQLQQEEEQL 943

Query: 787  LLEGLA--RWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRA 844
            L E     R +    Q  + + L ++  QLL +   +            RRQE+    R 
Sbjct: 944  LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR-----------RRQEREKKYRE 992

Query: 845  LWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLL-------RFA 897
                    + ++       + E R K+ R +W  Q  +   LQ+   +LL       R  
Sbjct: 993  --------EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044

Query: 898  ASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQ 932
               +  R++ + QQ+ +      R  RR   L +Q
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 117/545 (21%), Positives = 202/545 (37%), Gaps = 70/545 (12%)

Query: 253  QVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAER 312
            Q+++ +  R+  +Y +  KQ+     +  +  +KRR  ++ L++ +  R  RQQ E  +R
Sbjct: 707  QLESEADARQSKVYSRPRKQE--GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764

Query: 313  FHHVTVLQIYFCDWQ---QAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEE 369
                   + +   WQ   ++   R+ L A     E+  R+  LR      +    L  EE
Sbjct: 765  -------RDFTWQWQAEEKSERGRQRLSARPPLREQ--RERQLRAEERQQREQRFLPEEE 815

Query: 370  AAQFEMAEEHHRHSQLYFC--FRALKDNVTHAHLQQIRRNLAH-QQHGVTLLHRFWNLWR 426
              +    +   R  +L F      L+       LQ+    L   Q+   +   R    WR
Sbjct: 816  EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875

Query: 427  SQIEQKKERE-----LLPLLHAAWDHYRIALLCKCIELWLQYTQK-RRYKQLLQARADGH 480
             Q+E++++R        P L       +  L  +  EL  +  +K RR +Q  Q R +  
Sbjct: 876  WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935

Query: 481  FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE 540
             QQ           +    R QE     R  +  ++  E+ +     ++  Q RE +  E
Sbjct: 936  LQQEEEQLLREEREKR---RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992

Query: 541  RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR 600
               +   E QLL        ++   + + QEW+          + +K   L +E  Q LR
Sbjct: 993  EEELQQEEEQLL--------REEREKRRRQEWER---------QYRKKDELQQEEEQLLR 1035

Query: 601  TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT 660
             ER  R           L+    Q+RE   L+  E Q L       +   L R  +    
Sbjct: 1036 EEREKR----------RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085

Query: 661  YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV 720
             Q     +LRE   +  +  R+      R+ +E    + +E +   +     RR    + 
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERE------RQCREEEELQQEEEQLLREEREKRRRQELER- 1138

Query: 721  LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ 780
              Q+RE   VQ    Q+E+  + E  +   R  L    +R +       Q+  QL R  Q
Sbjct: 1139 --QYREEEEVQ----QEEEQLLREEPEKRRRQEL----ERQYREEEELQQEEEQLLREEQ 1188

Query: 781  HHHRQ 785
               RQ
Sbjct: 1189 EKRRQ 1193



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 3/89 (3%)

Query: 1147 LDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKEL 1206
            L  E   EE +QQLL  +  ++      R+    RR   L REE   E++ +EQ++++E 
Sbjct: 620  LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE---EEERLEQRLKREH 676

Query: 1207 EQVEMQIQLLAEELQAQRQPIGACVARIQ 1235
            E+   + +L  EE +  R+ I + + + Q
Sbjct: 677  EEERREQELAEEEQEQARERIKSRIPKWQ 705



 Score = 35.4 bits (80), Expect = 0.34
 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 5/81 (6%)

Query: 1150 EAELEEIQQQLLHYQTTKQNLWSCRRQASS----LRRWLELNREEPGPED-QEVEQQVQK 1204
            E EL++ ++QLL  +  K+      RQ        +   +L REEP     QE+E+Q ++
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172

Query: 1205 ELEQVEMQIQLLAEELQAQRQ 1225
            E E  + + QLL EE + +RQ
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQ 1193



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 11/82 (13%)

Query: 1152 ELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEP---GPED-----QEVEQQVQ 1203
            EL++ ++QLL  +  K+ L    RQ    R   EL +EE    G E      QE+E+Q +
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQ---YREEEELQQEEEQLLGEERETRRRQELERQYR 1081

Query: 1204 KELEQVEMQIQLLAEELQAQRQ 1225
            KE E  + + QLL EE + +R+
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRR 1103



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 1/76 (1%)

Query: 1150 EAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQV 1209
            E E E  +QQL   Q  ++     RR+   LRR  +L RE+    +Q++ ++ Q   EQ 
Sbjct: 354  EQEEERREQQLRREQEEERREQQLRRE-QQLRREQQLRREQQLRREQQLRREQQLRREQQ 412

Query: 1210 EMQIQLLAEELQAQRQ 1225
              + Q L  E Q +R+
Sbjct: 413  LRREQQLRREQQLRRE 428



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 22/77 (28%), Positives = 40/77 (51%)

Query: 1149 LEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQ 1208
            L+ E EE + QLL  +  ++     R Q   L + L+    E   +++  EQ++++E  +
Sbjct: 567  LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626

Query: 1209 VEMQIQLLAEELQAQRQ 1225
             E + QLL  E Q +R+
Sbjct: 627  EERRQQLLKSEEQEERR 643



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 21/72 (29%), Positives = 35/72 (48%)

Query: 1154 EEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQI 1213
            E  +QQL   Q  ++     RR+    RR  +L RE+    +Q++ ++ Q   EQ   + 
Sbjct: 345  ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404

Query: 1214 QLLAEELQAQRQ 1225
            Q L  E Q +R+
Sbjct: 405  QQLRREQQLRRE 416



 Score = 31.6 bits (70), Expect = 4.9
 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 7/83 (8%)

Query: 1149 LEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNRE-------EPGPEDQEVEQQ 1201
            L  E EE ++Q L  Q  ++ L    R    LRR  E  RE       E   E +  EQ+
Sbjct: 507  LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566

Query: 1202 VQKELEQVEMQIQLLAEELQAQR 1224
            +++E E+   Q+    EE + QR
Sbjct: 567  LKREQEERRDQLLKREEERRQQR 589



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 5/81 (6%)

Query: 1150 EAELEEIQQQLLHYQTT---KQNLWSCRRQASSLRRWLE-LNREEPGPED-QEVEQQVQK 1204
            E EL++ ++QLL  +     +Q L    R+   L++  E L REEP     QE E+Q ++
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112

Query: 1205 ELEQVEMQIQLLAEELQAQRQ 1225
            E E  + + QLL EE + +R+
Sbjct: 1113 EEELQQEEEQLLREEREKRRR 1133



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 10/82 (12%)

Query: 1148 DLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELE 1207
            D +    + QQ L H    +Q     R +    RRW +  R+   PE++++E++ QKE +
Sbjct: 1255 DSQLRDRQSQQDLQHLLGEQQE----RDREQERRRWQQ--RDRHFPEEEQLEREEQKEAK 1308

Query: 1208 ----QVEMQIQLLAEELQAQRQ 1225
                + + + QLL EE + +R+
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRR 1330


>gi|89027871 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 64/255 (25%), Positives = 88/255 (34%), Gaps = 44/255 (17%)

Query: 903  SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 957
            S   L+        H+  +  R    L  +      G+   LA+++P RK +       G
Sbjct: 139  SSDYLRVASGPMPVHTSSKRPRLDPILADRSATAMSGRGSVLASLSPLRKASLSSSSSLG 198

Query: 958  PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 1005
            P   +  A A          G   L   +P  SRP G    +  AA + H L    A   
Sbjct: 199  PKERQTGAAADMPQPAVRHEGREPLLVVKPTHSRPEGGCREVPQAASKTHGLP--QAARP 256

Query: 1006 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1054
            + Q +RP     P     P      GLG      P   RP  A     L           
Sbjct: 257  QAQDKRPAVTSLPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313

Query: 1055 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1110
             +P S + G    AP   QPP A+T  GP       S+    G   PA+V S  R  P  
Sbjct: 314  QIPESAIQGGELGAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHS 366

Query: 1111 KPPVPSSLASVPDPH 1125
            +P +P++ A     H
Sbjct: 367  RPCLPTAQACTMSHH 381


>gi|89027820 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 62/241 (25%), Positives = 86/241 (35%), Gaps = 44/241 (18%)

Query: 917  HSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----GPLLNRIAAGA---- 967
            H+  +  R    L  +      G+   LA+++P RK +       GP   +  A A    
Sbjct: 153  HTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQ 212

Query: 968  ------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSARKQPRRPHFLLEPA 1019
                  G   L   +P  SRP G    +  AA + H L    A   + Q +RP    +P 
Sbjct: 213  PAVRHQGREPLLVVKPTHSRPEGDCREVPQAASKTHGLL--QAARPQAQDKRPAVTSQPC 270

Query: 1020 QSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL------------VPHSPLPGALSSA 1067
                P      GLG      P   RP  A     L            +P S + G    A
Sbjct: 271  P---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGA 327

Query: 1068 PGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRDKPPVPSSLASVPDP 1124
            P   QPP A+T  GP       S+    G   PA+V S  R  P  +P +P++ A     
Sbjct: 328  PENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSH 380

Query: 1125 H 1125
            H
Sbjct: 381  H 381


>gi|51466907 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 64/255 (25%), Positives = 88/255 (34%), Gaps = 44/255 (17%)

Query: 903  SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 957
            S   L+        H+  +  R    L  +      G+   LA+++P RK +       G
Sbjct: 139  SSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLG 198

Query: 958  PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 1005
            P   +  A A          G   L   +P  SRP G    +  AA + H L    A   
Sbjct: 199  PKERQTGAAADIPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLL--QAARP 256

Query: 1006 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1054
            + Q +RP    +P     P      GLG      P   RP  A     L           
Sbjct: 257  QAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313

Query: 1055 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1110
             +P S + G    AP   QPP A+T  GP       S+    G   PA+V S  R  P  
Sbjct: 314  QIPESAIQGGELGAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSIDRQPPHS 366

Query: 1111 KPPVPSSLASVPDPH 1125
             P +P++ A     H
Sbjct: 367  TPCLPTAQACTMSHH 381


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 186/843 (22%), Positives = 305/843 (36%), Gaps = 148/843 (17%)

Query: 468  RYKQLLQARADGHFQQRALPAAFHTWNRLWRWR-----------HQENVLSARATRFH-- 514
            R ++L QAR +   Q  AL  A      L +              +   LS  ATR    
Sbjct: 846  REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLE 905

Query: 515  RETLEKQVFSLWRQ--KMFQHRENRLAERMAILHAERQLL-----YRSWFMWHQQAAARH 567
            +E LE  +F + RQ  ++   RE   AE  A+L A+  L       R   +  Q+ A+  
Sbjct: 906  KEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLD 965

Query: 568  QEQEWQTVACAHHR-HGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWR 626
            +E   Q +  A       L++      E  Q L+ E+    R  E   AQL      +  
Sbjct: 966  KELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE 1025

Query: 627  ECLALRGAERQKLMR--ADLHHQHS----VLHRALQAWVTYQGRVRSILREVAARESQHN 680
            E LA   AE+++L    A L  +      +     Q  ++ +   ++ L E     ++H+
Sbjct: 1026 ELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSE-KLMGTRHS 1084

Query: 681  RQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSK----VLVQWREAVSVQMYYR- 735
               +   + R K +  +R ++ + T  A T   R + ++         +E   +Q   R 
Sbjct: 1085 LATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARD 1144

Query: 736  --QQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHH--RQLLLEGL 791
              +Q D  + EA++      LRT  +   D      ++ L+ +R ++     R++  +  
Sbjct: 1145 LGKQRDSCLREAEE------LRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA 1198

Query: 792  ARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFS 851
               +    +  ++R   R+S + L   + +    +   +LA   +EQ+  +      A  
Sbjct: 1199 GELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVG 1258

Query: 852  LQAKVWATWLAFV----LERRRK--------------KARLQWALQAYQGQL-LQEGAT- 891
             +A    T L  V    LE RR+                RL   L   QG+L L E A  
Sbjct: 1259 KEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEK 1318

Query: 892  -----------RLLRFAASMKASRQQLQ-AQQQVQAAHSLHRAVRRCATLWKQKVLGRGG 939
                       RLL+  AS++  RQ+LQ AQ+++Q      R   R   L       RG 
Sbjct: 1319 ESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRER--RLLGSLEEARGT 1376

Query: 940  KPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALG-RLAAEEPHALE 998
            + Q L                   A G     LE K   A      LG RL+A E  A  
Sbjct: 1377 EKQQLDH-----------------ARG-----LELKLEAARAEAAELGLRLSAAEGRAQG 1414

Query: 999  LNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHS 1058
            L  A  AR + +R       AQ    +     GLG+ +  +P+  RP         VP S
Sbjct: 1415 LE-AELARVEVQR---RAAEAQLGGLRSALRRGLGLGRAPSPA-PRP---------VPGS 1460

Query: 1059 PLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSL 1118
            P   A +   G                        G  +P   S    +P  +PP P   
Sbjct: 1461 PARDAPAEGSGE-----------------------GLNSP---STLECSPGSQPPSPGPA 1494

Query: 1119 ASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQAS 1178
             S   P L    D  A R             + E +E++ Q          + + R  A+
Sbjct: 1495 TSPASPDL----DPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSAT 1550

Query: 1179 SLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALR 1238
            S  R L    ++   E +E  + V   L  V+ ++ L  E ++   +   A + ++  L 
Sbjct: 1551 SRARQL----QKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLE 1606

Query: 1239 QAL 1241
            ++L
Sbjct: 1607 RSL 1609


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 26/176 (14%)

Query: 977  PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQ 1036
            P AS PL  L   + + P+AL ++   +    P  P     P Q+  P  P       + 
Sbjct: 636  PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQA--PFSPPA-----SP 683

Query: 1037 PAAPSLTRPFLA----EAPTALVPHSP---LPGALSSAPGPKQPPTASTGPELL--LLPL 1087
            P +PS T P  A     AP   VP SP    P + S+ P P+ PP  +  P  +    P 
Sbjct: 684  PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 1088 SSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLST 1143
            S  M   A  P RV    A P  + P PS  AS+P   L  P      +A P L+T
Sbjct: 744  SPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKP----PPQAPPALAT 794



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 58/234 (24%), Positives = 88/234 (37%), Gaps = 39/234 (16%)

Query: 939  GKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALE 998
            G P+P  +  P  +   EGP   +  + A + +     P A R   A G L  + P +  
Sbjct: 188  GLPRPAPSARP--RPPTEGP--RKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRS 241

Query: 999  LNTAHSARKQPRR--PHFLLEPAQSQRPQKPQEHGLGMAQP---------AAPSL----T 1043
            L+++ +    P R  P     P     P +P+  GL   +P         AAP+L    +
Sbjct: 242  LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 1044 RPFLAEAPTAL----VPH-----SPLPGALSSAPG-----PKQPPTASTGPELLLLPLSS 1089
             P    +P+      VP      +PLP  L  +P      P  PP+ S  P L  LP   
Sbjct: 302  SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361

Query: 1090 FMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLST 1143
              P   A P+  +     P   PP   ++  +  PH L      A  +   LS+
Sbjct: 362  ATPPSQAPPSMTT----PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411



 Score = 39.7 bits (91), Expect = 0.018
 Identities = 41/127 (32%), Positives = 52/127 (40%), Gaps = 10/127 (7%)

Query: 1004 SARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSP---L 1060
            SA   P+ P  L  P     P  P      M+  A P    P L  AP   VP SP   L
Sbjct: 719  SATPPPQAPPPLAAPPLQVPPSPPASPP--MSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 1061 PGALSSAPGPKQPPTASTGP-ELLLLPLSSF---MPCGAAAPARVSAQRATPRDKPPV-P 1115
            P +  + P P+ PP  +T P + L  P +SF    P   +A   +S     P   PPV  
Sbjct: 777  PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836

Query: 1116 SSLASVP 1122
            + L  VP
Sbjct: 837  APLLQVP 843



 Score = 38.9 bits (89), Expect = 0.031
 Identities = 31/116 (26%), Positives = 42/116 (36%), Gaps = 5/116 (4%)

Query: 1012 PHFLLEPAQS--QRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPG 1069
            P   L P Q+    P  P    L    P AP+     L +AP +  P  P+    S    
Sbjct: 623  PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 1070 PKQPPTA---STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVP 1122
            P   P+A   S  P  L  P     P   A+P    +    P+  PP+ +    VP
Sbjct: 683  PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 52/172 (30%), Positives = 56/172 (32%), Gaps = 25/172 (14%)

Query: 977  PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQK-----PQEHG 1031
            P    PL AL  LA+  P A       S    P      L P   Q P       P E+ 
Sbjct: 483  PLTIHPLQALSSLASHSPQA----PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538

Query: 1032 LGMAQP----AAPSLTRPFLAEAPTAL-----VPHSPL----PGALSS-APGPKQPPTAS 1077
              +A P    A+  LT P L   P         P SPL    P   SS A  P Q P A 
Sbjct: 539  PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598

Query: 1078 TGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLP 1129
              P L  LP     P     P         P   PP P   AS P   L  P
Sbjct: 599  ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP--ASPPLSPLATP 648



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 47/202 (23%), Positives = 67/202 (33%), Gaps = 33/202 (16%)

Query: 977  PQASRPLGALGRLAAEEPHALELNTAHSARKQPRR----------PHFLLEPAQSQRPQK 1026
            P AS P+  L +   + P AL      +    P                + P  +  PQ 
Sbjct: 772  PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 831

Query: 1027 PQEHGLGMAQ-----PAAPSLTRPFLAEAPTALVPHSPLPG---ALSSAPGPKQPPTAST 1078
            P      + Q     PA+P+L  P     P    P + + G    L+ APGP  PP+ S 
Sbjct: 832  PPVLAAPLLQVPPSPPASPTLQAP---RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888

Query: 1079 GPELLLLPLSSFMPCGAAAPARVSAQRATPRD----KPPVPSSLASV--------PDPHL 1126
               L    L+       + P  +    + P       PP  + LA+         P P L
Sbjct: 889  SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948

Query: 1127 LLPGDFSATRAGPGLSTAGSLD 1148
               G   A    P  +  GS D
Sbjct: 949  AFRGAPGAPLPWPPATGPGSAD 970



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 56/205 (27%), Positives = 72/205 (35%), Gaps = 26/205 (12%)

Query: 940  KPQPLAA-----IAPSRKVTFE--GPLLNR-IAAGAGDGTLETKRP---QASRPLGALGR 988
            KP+ L A     + P RK      GPL +  +A  +  GT     P    A+ PL A   
Sbjct: 273  KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT-- 330

Query: 989  LAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLA 1048
            L    P A  L  A  +   P     L  P  +   Q P      M  P  P    P L 
Sbjct: 331  LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS----MTTP--PMQAPPSLQ 384

Query: 1049 EAPTALVPHSPLPGALSSAPGPK-----QPPTASTGPELLLLPLSSFMPCGAAAPARVSA 1103
              P   VPHS    +L + P P      Q  T+   P L        M       +  S 
Sbjct: 385  TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444

Query: 1104 QR--ATPRDKPPVPSSLASVPDPHL 1126
             R  +TP D PP+ + L+    P L
Sbjct: 445  SRPASTPPDSPPLQAPLSLPASPPL 469


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 91/381 (23%), Positives = 141/381 (37%), Gaps = 68/381 (17%)

Query: 904  RQQLQAQQQVQAAHSLHRAV------RRCATLWKQKVLGRGGKPQ--PLAAIAPSRKVTF 955
            +QQ Q QQQ Q  HS   A+      R    L  Q + G G +P   P    A   ++T 
Sbjct: 3600 QQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTP 3659

Query: 956  EGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAAEE----PHALELNTA--------- 1002
             G  L     G    T   ++ Q     GA G LA       P  L L +          
Sbjct: 3660 GGMALPGQPGGPFLNTALAQQQQQQHSGGA-GSLAGPSGGFFPGNLALRSLGPDSRLLQE 3718

Query: 1003 HSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-----QPAAPSL-TRPFLAEAPTALVP 1056
               + Q +R     +  Q Q+ Q+ Q+H LG       Q   P + T   L   P  L+P
Sbjct: 3719 RQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMP 3778

Query: 1057 HSPLPGALSS--APGPKQPPTASTGP-ELLLLPLSSFMPCGAAAPAR------------- 1100
             S   G L    +P P Q P    GP ++ +L        G   P R             
Sbjct: 3779 PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSP 3838

Query: 1101 --------------VSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTA-- 1144
                          V+AQ+   + +     S+A +      L     +    P LS    
Sbjct: 3839 QLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH----LQQSLMSHSGQPKLSAQPM 3894

Query: 1145 GSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQK 1204
            GSL    + +++QQQ    Q  +Q L    +Q   L++     +++     Q+ +QQ+Q+
Sbjct: 3895 GSLQQLQQQQQLQQQQQLQQQQQQQL----QQQQQLQQQQLQQQQQQQQLQQQQQQQLQQ 3950

Query: 1205 ELEQVEMQIQLLAEELQAQRQ 1225
            + +Q++ Q Q   ++ Q Q+Q
Sbjct: 3951 QQQQLQQQQQQQQQQFQQQQQ 3971



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 49/184 (26%), Positives = 70/184 (38%), Gaps = 17/184 (9%)

Query: 974  TKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPA--QSQRPQKPQEHG 1031
            T  P     LGA  R  A +P         + R QP  P   L+P          P+  G
Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262

Query: 1032 LGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQ---PPTASTGPELLLLPLS 1088
            +G  + + P L+ P   E+  AL       GA S + GP       + S+G  L  L L 
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELK 2322

Query: 1089 SFMPCGAAAPARVSAQRATPR--------DKPPVPSSLASVPDPH--LLLPGDFSATRAG 1138
            +  P    AP    A +  P+         +PP   +LA  P  H  +  PG ++   A 
Sbjct: 2323 T--PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ 2380

Query: 1139 PGLS 1142
            P L+
Sbjct: 2381 PPLT 2384



 Score = 38.5 bits (88), Expect = 0.040
 Identities = 37/146 (25%), Positives = 48/146 (32%), Gaps = 11/146 (7%)

Query: 992  EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP 1051
            EEPH   +        QP   H   +  +     +P+E  L       P   RP   E P
Sbjct: 811  EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP---EKP 867

Query: 1052 TALVPHSPLPGALSSAPGPKQP--------PTASTGPELLLLPLSSFMPCGAAAPARVSA 1103
                   P P  L   P P +P        P  S   E  L PL   +P   +    +S 
Sbjct: 868  PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927

Query: 1104 QRATPRDKPPVPSSLASVPDPHLLLP 1129
            Q   P   PP  S + +   P  L P
Sbjct: 928  QLMPPDPLPPPLSPIITAAAPPALSP 953



 Score = 37.4 bits (85), Expect = 0.090
 Identities = 69/259 (26%), Positives = 91/259 (35%), Gaps = 37/259 (14%)

Query: 900  MKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPL 959
            ++  +QQL  QQQ  AA S+  A+           LGR     PLA I+        GP 
Sbjct: 2810 LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGIS----TRLPGP- 2864

Query: 960  LNRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPA 1019
               +   AG       R    + LG  G             T    +  P+RP F     
Sbjct: 2865 GEPVPGPAGPAQFIELRHNVQKGLGPGG-------------TPFPGQGPPQRPRFY---P 2908

Query: 1020 QSQRPQKPQEHGL-GMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTAST 1078
             S+ P +    GL G+A    P    P    AP    P   L  +L   P  K  PT  T
Sbjct: 2909 VSEDPHRLAPEGLRGLAVSGLP----PQKPSAP----PAPELNNSLHPTPHTK-GPTLPT 2959

Query: 1079 GPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAG 1138
            G EL+  P SS    G   P  + A +  P + P +        D H  L  D      G
Sbjct: 2960 GLELVNRPPSS-TELGRPNPLALEAGK-LPCEDPELDDDF----DAHKALEDDEELAHLG 3013

Query: 1139 PGLSTAGSLDLEAELEEIQ 1157
             G+  A   D    LE ++
Sbjct: 3014 LGVDVAKGDDELGTLENLE 3032



 Score = 34.3 bits (77), Expect = 0.76
 Identities = 77/341 (22%), Positives = 131/341 (38%), Gaps = 58/341 (17%)

Query: 774  QLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAA 833
            Q ++  Q H +Q  + GL+     HLQ  +  + H    +L AQ +      Q +QQL  
Sbjct: 3856 QQQQQQQQHQQQGSMAGLS-----HLQ--QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQ 3908

Query: 834  RRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRL 893
            ++Q Q+   + L       Q ++    L    ++++ + + Q  LQ  Q QL Q+   + 
Sbjct: 3909 QQQLQQQQQQQL-----QQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQ 3963

Query: 894  LRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPL------AAI 947
             +F        QQ Q QQQ+   +     +       +Q  LG G   +PL       A+
Sbjct: 3964 QQF--------QQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL 4015

Query: 948  APSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPL--GALGRLAAEEPHALELNTAHSA 1005
             P+  +T  G   N +         E        PL  G      A EP  ++ + +  +
Sbjct: 4016 GPTLLLT--GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDS 4073

Query: 1006 -------RKQPRRPHFLLEPAQSQRPQKPQE-----------HG-LGMAQPAAPSLTRPF 1046
                   + QP+     L+P      Q+ Q+           HG LG    +  S     
Sbjct: 4074 QLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHL 4133

Query: 1047 LAEAPTALVPHSPLPGALS-SAPGPKQPPTA-----STGPE 1081
            LA+   +L      PG+++ +  GP+QP        +TGP+
Sbjct: 4134 LAQPSVSL---GDQPGSMTQNLLGPQQPMLERPMQNNTGPQ 4171



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 49/205 (23%), Positives = 78/205 (38%), Gaps = 11/205 (5%)

Query: 1016 LEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF----LAEAPTALVPHSPLPGALSSAPGPK 1071
            L P +   P    E  L     A+P L+ PF    L+  P  L P SP P A   +P P+
Sbjct: 520  LSPPEESPPSPALETPLSPPPEASP-LSPPFEESPLSPPPEEL-PTSPPPEASRLSPPPE 577

Query: 1072 QPPTASTGPELLLLP---LSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVP-DPHLL 1127
            + P +    E  + P    S   P    +P     +  +P   PP  S L+  P D  + 
Sbjct: 578  ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE-SPLSPPPEASRLSPPPEDSPMS 636

Query: 1128 LPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELN 1187
             P + S     P +S    L + + L    ++       +++  S   +AS L    E +
Sbjct: 637  PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS 696

Query: 1188 REEPGPEDQEVEQQVQKELEQVEMQ 1212
               P PED       +  L  + ++
Sbjct: 697  PTSPPPEDSPASPPPEDSLMSLPLE 721



 Score = 32.3 bits (72), Expect = 2.9
 Identities = 49/177 (27%), Positives = 68/177 (38%), Gaps = 13/177 (7%)

Query: 940  KPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASR-PLGALGRLAAEEPHALE 998
            K + L A +PS      G  ++  ++G   G LE K P   + PL    R +  EP +  
Sbjct: 2288 KKEELGASSPSYGPPNLG-FVDSPSSGTHLGGLELKTPDVFKAPLTP--RASQVEPQSPG 2344

Query: 999  LNTAHSARKQPRRPHFLLEPAQSQRPQ--KPQEHGLGMAQPAAPSLTRPFLAEAPTALVP 1056
            L      R Q   P   L P+    P   +P  +    AQP      +P   E+  AL P
Sbjct: 2345 LGL----RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400

Query: 1057 HSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPP 1113
             S      S  P   Q  ++S  P L   PLS+   C   +P     Q   P  +PP
Sbjct: 2401 RSLPSDPFSRVPASPQSQSSSQSP-LTPRPLSAEAFC--PSPVTPRFQSPDPYSRPP 2454



 Score = 30.8 bits (68), Expect = 8.4
 Identities = 29/119 (24%), Positives = 44/119 (36%), Gaps = 7/119 (5%)

Query: 1016 LEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPT 1075
            L P   + P  P    L +++P   S   P   E+P +  P S     L  +  P  PP 
Sbjct: 467  LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES--PLSPPE 524

Query: 1076 ASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK-----PPVPSSLASVPDPHLLLP 1129
             S     L  PLS        +P    +  + P ++     PP  S L+  P+   + P
Sbjct: 525  ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 190/1010 (18%), Positives = 372/1010 (36%), Gaps = 255/1010 (25%)

Query: 19   VIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCT 78
            VI+Q+ +    ++  +   +++ +SA  L      A+F   R + +  HL     + T  
Sbjct: 2363 VIQQQYQANRAAKLQRQHYLRQRHSAVILQ-----AAF---RGMKTRRHLKSMHSSATLI 2414

Query: 79   RQGRLREL--RIRCVARKFLYLWIRMTFGRVFPSKARFY---------------YEQRLL 121
             Q R R L  R R ++ K   ++++  +     +K + Y               Y + ++
Sbjct: 2415 -QSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMV 2473

Query: 122  RKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVH 181
            +K  +E +          +  V     +R Y   + FQTWK      Q+    Y  A++ 
Sbjct: 2474 KKKLQEMQ----------RAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQ 2523

Query: 182  DAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALH 241
              ++   + W S ++     +     Q    + +  I+++  +  +RQ     ++  A  
Sbjct: 2524 --RENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATK 2581

Query: 242  ASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRR 301
                K+RA                   K+KQKV      H   +K   ++A  + + +++
Sbjct: 2582 IIQEKYRA------------------NKKKQKVFQ----HNELKKETCVQAGFQDMNIKK 2619

Query: 302  VKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKH 361
              ++Q       H   ++    C   +A++ R+      A V  + R+    R  T  + 
Sbjct: 2620 QIQEQ-------HQAAIIIQKHC---KAFKIRKHYLHLRATVVSIQRRY---RKLTAVRT 2666

Query: 362  YMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRF 421
              ++C +                    +R  K          +R+++ +     TL+  F
Sbjct: 2667 QAVICIQSY------------------YRGFK----------VRKDIQNMHRAATLIQSF 2698

Query: 422  WNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHF 481
            + + R++++ + ++  + ++    ++YR+ +  K        T+++ +  + ++      
Sbjct: 2699 YRMHRAKVDYETKKTAIVVIQ---NYYRLYVRVK--------TERKNFLAVQKS------ 2741

Query: 482  QQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAER 541
              R + AAF                                    RQK+    E ++A  
Sbjct: 2742 -VRTIQAAFRGMKV-------------------------------RQKLKNVSEEKMA-- 2767

Query: 542  MAILHAERQLLYRSWFMWHQQAAARHQEQEWQT---VACA----HHRHGR----LKKAFC 590
             AI++      YRS   +    +     QEW     +AC+    +H   R    ++KAFC
Sbjct: 2768 -AIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFC 2826

Query: 591  LWRESAQGLRTERTGRVRAAEF-HMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHS 649
              R   + L T++   +R   F  MA   R    Q R  + L     Q   R     +  
Sbjct: 2827 --RMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITL-----QHYFRTWQTRKQF 2879

Query: 650  VLHRALQAWVTYQGRVRSILREVAARESQHNRQL---LRGALRRWKENTMARVDEAK--- 703
            +L+R  +A V  Q   R+ L       ++H RQ+   +R ++   +  +   + + K   
Sbjct: 2880 LLYR--KAAVVLQNHYRAFL------SAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQE 2931

Query: 704  ---KTFQASTHYRRTICSKVLVQWREAVSVQMYYR----QQEDCAIWEAQKVLDRGCLRT 756
                T +    +RR    K L + + A  +Q +YR     +E  AI +A K++ +GC  T
Sbjct: 2932 IKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKII-QGCFYT 2990

Query: 757  WFQRWWDCSRRSA------QQRLQLERAVQHHHRQLLLEGLARWKTHHLQCV-------- 802
              +R    + R++      + R  L   + H H  ++       K H   C+        
Sbjct: 2991 KLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMI-------KRHRAACLIQAHYRGY 3043

Query: 803  --RKRLLHRQSTQLLAQRLSR-----------------------TCFRQWRQQLAARRQE 837
              R+  L ++S  L+ Q+  R                          R W   +  R  E
Sbjct: 3044 KGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKSTVILQALVRGW--LVRKRFLE 3101

Query: 838  QRATVRALWFWA---FSLQA----KVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGA 890
            QRA +R L F A   + L A    + +  +LA  ++   K+      +Q +    LQE  
Sbjct: 3102 QRAKIRLLHFTAAAYYHLNAVRIQRAYKLYLA--VKNANKQVNSVICIQRWFRARLQE-- 3157

Query: 891  TRLLRFAASMKASRQQLQ--AQQQVQAAHSLHRAVRRCATLWKQKVLGRG 938
             R ++   S+K    + Q    Q+ +AA  + +AVR      KQ+    G
Sbjct: 3158 KRFIQKYHSIKKIEHEGQECLSQRNRAASVIQKAVRHFLLRKKQEKFTSG 3207



 Score = 34.7 bits (78), Expect = 0.58
 Identities = 73/344 (21%), Positives = 126/344 (36%), Gaps = 77/344 (22%)

Query: 141  LCVRA-DCHYRYYLYNLMFQTWKTYV-------RQQQEMRNKYIRAEVHD--AKQKMRQA 190
            LC R  D         L+  TW+ Y         Q++E   + I+  V +  AKQ++R+ 
Sbjct: 1256 LCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKR 1315

Query: 191  WKSWLIY------VVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASA 244
              + L+       V+ +R  L ++   LE  Q     +    WR      R S       
Sbjct: 1316 VNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWR------RYSTRQRFLK 1369

Query: 245  LKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHW----------QKRRFLKAWL 294
            LK+ ++ LQ +        ++ V   K+ + + V   +HW          Q+   LK+  
Sbjct: 1370 LKYYSIILQSRI-----RMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSST 1424

Query: 295  EYLQVRRVKRQQNEMAERFHHVTVLQIYFCDW---QQAWERR-----ESLYAHHAQVEKL 346
              +Q    K +Q +M  +     +LQ  F +W   +QA E       +S Y  H ++ K 
Sbjct: 1425 LIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKY 1484

Query: 347  ------------------ARKMALRR---AFTHWKHYMLLCAEEAAQFEMAEEHHRHSQL 385
                              A+K+  RR     T  K+Y      +  +    ++     QL
Sbjct: 1485 IYIRSCVVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQL 1544

Query: 386  YFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHRFWNLWRSQI 429
               FR LK     AH      NL  Q     ++  +W + + ++
Sbjct: 1545 QAAFRRLK-----AH------NLCRQIRAACVIQSYWRMRQDRV 1577


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 91/553 (16%), Positives = 194/553 (35%), Gaps = 96/553 (17%)

Query: 327 QQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLY 386
           ++ W + E L     ++ K   KM        W+    L  +E    E  E+  R     
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKM--------WRQEERLREQEGKMREQEEKMRRQE--- 282

Query: 387 FCFRALKDNVTHAHLQQ--IRRNLAHQQHGVTLLHRFWNLWRSQIEQKKERELLPLLHAA 444
              + L++       Q+  +R     ++    +  +   +W  + + +++ E +      
Sbjct: 283 ---KRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM------ 333

Query: 445 WDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQ----RALPAAFHTWNRLW--- 497
           W             LW Q  Q R  +Q ++ + +  ++Q    R          ++W   
Sbjct: 334 WRQEE--------RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQE 385

Query: 498 -------RWRHQENVL--SARATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAE 548
                  R R +E  +       R   E ++KQ  ++W Q+  + ++ RL E+   L  +
Sbjct: 386 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 445

Query: 549 RQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVR 608
            ++  +   +W Q+   R QE+ W          G+ KK   +WR+       E+  ++ 
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMW----------GQEKK---MWRQEKM---REQEDQMW 489

Query: 609 AAEFHMAQLLRWAWSQ----WRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGR 664
             E  M    +  W Q    W +   LR  E +   +  +  Q   +    +   T +  
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK---TQEQE 546

Query: 665 VRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQW 724
            ++  +E   RE +  R+  +   +  +E  M R  E K   Q           + + + 
Sbjct: 547 KKTWDQEEKMREEERMREREK---KMREEEEMMREQEEKMQEQ----------EEKMREQ 593

Query: 725 REAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHR 784
            E +  Q    Q+++  +WE ++       + W Q   D  +   +   + E  +Q    
Sbjct: 594 EEKMWEQEEKMQEQEEKMWEQEE-------KMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646

Query: 785 QLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRA 844
           ++       W+       ++  +  Q  ++  Q        +  Q    + +EQ   +R 
Sbjct: 647 KM-------WEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRG 699

Query: 845 LWFWAFSLQAKVW 857
                +  + K+W
Sbjct: 700 QEEKMWGQEEKMW 712


>gi|51466802 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 58/214 (27%), Positives = 78/214 (36%), Gaps = 44/214 (20%)

Query: 944  LAAIAPSRKVTFE-----GPLLNRIAAGA----------GDGTLETKRPQASRPLGALGR 988
            LA+++P RK +       GP   +  A A          G   L   +P  SRP G    
Sbjct: 180  LASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCRE 239

Query: 989  L--AAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF 1046
            +  AA + H L    A   + Q +RP    +P     P      GLG      P   RP 
Sbjct: 240  VPQAASKTHGLL--QAARPQAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPA 294

Query: 1047 LAEAPTAL------------VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMP 1092
             A     L            +P S + G    AP   QPP A+T  GP       S+   
Sbjct: 295  QAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGP-------STSPQ 347

Query: 1093 CGAAAPARV-SAQRATPRDKPPVPSSLASVPDPH 1125
             G   PA+V S  R  P  +P +P++ A     H
Sbjct: 348  MGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHH 381


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 63/218 (28%), Positives = 86/218 (39%), Gaps = 34/218 (15%)

Query: 931  KQKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLA 990
            K++   R    Q LA +   ++   +G LL R+A+GA   + E +R +AS  L   G   
Sbjct: 1076 KERWSKRARPQQDLARLVMEKR---QGRLLLRLASGASSSSSEEQR-RASETLSGTG--- 1128

Query: 991  AEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSL-------T 1043
            +EE        A   RK  R        A + R + P+  GL M  P A           
Sbjct: 1129 SEEDTPASEPAAALPRKSGR--------AAATRSRIPRPIGLRMPMPVAAQQPASRSHGA 1180

Query: 1044 RPFLAEAPTALVPHSPLPGALSSAP-GPKQPPTASTGPELLLLPLSSFMPCGAAAPARVS 1102
             P L  A T+ +     PG+ ++A   PKQPP    GP           P     PA  S
Sbjct: 1181 APALDTAITSRLQLQTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTS 1240

Query: 1103 AQR---ATPRD------KPPVPSSLA--SVPDPHLLLP 1129
            A R   A+PR       + P PS  A   VP P  + P
Sbjct: 1241 AARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVPP 1278


>gi|211971097 hypothetical protein LOC441317 [Homo sapiens]
          Length = 464

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 63/255 (24%), Positives = 88/255 (34%), Gaps = 44/255 (17%)

Query: 903  SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 957
            S + L+        H+  +  R    L  +      G+   LA+++P RK +       G
Sbjct: 139  SSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLG 198

Query: 958  PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 1005
            P   +  A A          G   L   +P  S P G    +  AA + H L    A   
Sbjct: 199  PKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLL--QAVRP 256

Query: 1006 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1054
            + Q +RP    +P     P      GLG      P   RP  A     L           
Sbjct: 257  QAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313

Query: 1055 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1110
             +P S + G    AP   QPP A+T  GP       S+    G   PA+V S  R  P  
Sbjct: 314  QIPESAIQGGELRAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHS 366

Query: 1111 KPPVPSSLASVPDPH 1125
             P +P++ A     H
Sbjct: 367  TPCLPTAQACTMSHH 381


>gi|169173146 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 63/255 (24%), Positives = 90/255 (35%), Gaps = 44/255 (17%)

Query: 903  SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 957
            S   L+  +     H+  + +R    L  +      G+   LA+++P RK +       G
Sbjct: 139  SSDYLRVARGPMPVHTTSKRLRMDPVLSGRSATEMSGRGSVLASLSPLRKASLSSSSSLG 198

Query: 958  PLLNRIAAGAG----------DGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 1005
            P   +  A A             TL    P  S P G+   +  AA + H L    A   
Sbjct: 199  PKERQTGAAADIPRPAVRHQVHETLLVVEPTHSSPEGSCREVPQAASKTHGLL--QAVRT 256

Query: 1006 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1054
            + Q +RP    +P  S         GLG      P   RP  A     L           
Sbjct: 257  QAQDKRPAVTSQPCPSAATHSL---GLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313

Query: 1055 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1110
             +P S + G    AP   QPP A+T  GP       S     G   PA+V S +R  P  
Sbjct: 314  QIPESTIQGGELGAPENLQPPPAATELGP-------SRSPQMGRRTPAQVPSVERQPPHR 366

Query: 1111 KPPVPSSLASVPDPH 1125
            +P +P++ A     H
Sbjct: 367  RPCLPTAQACTMSHH 381


>gi|239742272 PREDICTED: hypothetical protein XP_002342469 isoform 2
            [Homo sapiens]
          Length = 464

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 58/214 (27%), Positives = 79/214 (36%), Gaps = 44/214 (20%)

Query: 944  LAAIAPSRKVTFE-----GPLLNRIAAGA----------GDGTLETKRPQASRPLGALGR 988
            LA+++P RK +       GP   +  A A          G   L   +P  S P G    
Sbjct: 180  LASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSPEGGCRE 239

Query: 989  L--AAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF 1046
            +  AA + H L    A S + Q +RP    +P     P      GLG      P   RP 
Sbjct: 240  VPQAASKTHGLL--QAISPQAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPA 294

Query: 1047 LAEAPTAL------------VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMP 1092
             A     L            +P S + G    AP   QPP A+T  GP       S+   
Sbjct: 295  QAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPEYLQPPPATTELGP-------STSPQ 347

Query: 1093 CGAAAPARVSA-QRATPRDKPPVPSSLASVPDPH 1125
             G   PA+VS+  R  P  +P +P++ A     H
Sbjct: 348  MGRRTPAQVSSVDRQPPHSRPCLPTAQACTMSHH 381


>gi|239742270 PREDICTED: hypothetical protein XP_002342468 isoform 1
            [Homo sapiens]
          Length = 464

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 58/214 (27%), Positives = 79/214 (36%), Gaps = 44/214 (20%)

Query: 944  LAAIAPSRKVTFE-----GPLLNRIAAGA----------GDGTLETKRPQASRPLGALGR 988
            LA+++P RK +       GP   +  A A          G   L   +P  S P G    
Sbjct: 180  LASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSPEGGCRE 239

Query: 989  L--AAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF 1046
            +  AA + H L    A S + Q +RP    +P     P      GLG      P   RP 
Sbjct: 240  VPQAASKTHGLL--QAISPQAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPA 294

Query: 1047 LAEAPTAL------------VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMP 1092
             A     L            +P S + G    AP   QPP A+T  GP       S+   
Sbjct: 295  QAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPEYLQPPPATTELGP-------STSPQ 347

Query: 1093 CGAAAPARVSA-QRATPRDKPPVPSSLASVPDPH 1125
             G   PA+VS+  R  P  +P +P++ A     H
Sbjct: 348  MGRRTPAQVSSVDRQPPHSRPCLPTAQACTMSHH 381


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 55/211 (26%), Positives = 79/211 (37%), Gaps = 35/211 (16%)

Query: 939  GKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPL--GALGRLAAEE--- 993
            G P+P  +  P  +   EGP  + +++ +   T E       RP   G L R A+     
Sbjct: 188  GLPRPAPSARP--RPPTEGPRKS-VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244

Query: 994  ---PHALELNTAHSARKQPRRPHF----------LLEPAQSQRPQKPQEHGLGMAQP--- 1037
               P +    +  SAR  PR P             L P Q   P+K     LG       
Sbjct: 245  SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304

Query: 1038 AAPSLTRPFLAEAPTAL--VPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGA 1095
            A PS +    ++AP  L   PHS       + P P  PP+ S  P L  LP         
Sbjct: 305  ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP--------- 355

Query: 1096 AAPARVSAQRATPRDKPPVPSSLASVPDPHL 1126
            + PA   +Q  T    P + ++ + +P P L
Sbjct: 356  SPPATPPSQATTSLGSPTLQATHSFLPSPPL 386



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 46/157 (29%), Positives = 60/157 (38%), Gaps = 13/157 (8%)

Query: 977  PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQ 1036
            P AS PL  L   + + P+AL ++   +    P  P     P Q+  P  P         
Sbjct: 411  PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQA--PFSPPASPPVSPS 463

Query: 1037 PAAPSLTRPFLAEAPTALVPHSPL--PGALSSAPGPKQPPTASTGPELLLLPLSSFMPCG 1094
               PS   P LA  P  + P  P   P + S+ P P+ PP  +  P  L  P     P  
Sbjct: 464  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523

Query: 1095 AAAP--ARVSAQRATPRDKPPVPSSLASVPDPHLLLP 1129
            A  P  A  S   + P   P  PS  AS+P   L  P
Sbjct: 524  ATPPLQALPSPPASFPGQAPFSPS--ASLPMSPLATP 558



 Score = 37.7 bits (86), Expect = 0.069
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 8/119 (6%)

Query: 1012 PHFLLEPAQS--QRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPG 1069
            P   L P Q+    P  P    L    P AP+     L +AP +  P  P+    S    
Sbjct: 398  PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457

Query: 1070 PKQPPTA---STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPV---PSSLASVP 1122
            P   P+A   S  P  L  P     P   A+P    +    P+  PP+   P  LA  P
Sbjct: 458  PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516



 Score = 35.8 bits (81), Expect = 0.26
 Identities = 51/217 (23%), Positives = 66/217 (30%), Gaps = 45/217 (20%)

Query: 977  PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEH------ 1030
            P AS P+        + P  L       A+  P+ P  L  P     P  P         
Sbjct: 485  PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544

Query: 1031 ----GLGMAQPAAPSLTRPFLAEAPTALVPHSP-------------LPG----------A 1063
                 L M+  A P    P +  AP   VP SP              PG           
Sbjct: 545  SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604

Query: 1064 LSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRD----KPPVPSSLA 1119
            L+ APGP  PP+ S    L    L+       + P  +    + P       PP  + LA
Sbjct: 605  LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 664

Query: 1120 SV--------PDPHLLLPGDFSATRAGPGLSTAGSLD 1148
            +         P P L   G   A    P  +  GS D
Sbjct: 665  ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 56/209 (26%), Positives = 80/209 (38%), Gaps = 30/209 (14%)

Query: 948  APSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALG-RLAAEEPHALELNT----- 1001
            AP  K T  GP+ +    G   GT    RP    PLG  G R++AEE  A    T     
Sbjct: 103  APPAKNTSPGPVSS---PGRASGTT---RPG---PLGQKGLRISAEETVARGKATEAPKR 153

Query: 1002 ---AHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHS 1058
               +  AR+    P          R  +     +G+ +PA  +  RP   E P   V  +
Sbjct: 154  SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPRKSVSSA 212

Query: 1059 PLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGA---AAPARVS-AQRATPR----D 1110
                    +P  ++ P+A  G   L  P S  +   A   ++PAR   + R TPR     
Sbjct: 213  SEHSTTEPSPAARRRPSAGGG---LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269

Query: 1111 KPPVPSSLASVPDPHLLLPGDFSATRAGP 1139
              P P  L ++  P +  P   +A   GP
Sbjct: 270  SQPKPKGLQALRPPQVTPPRKDAAPALGP 298


>gi|51466913 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 63/255 (24%), Positives = 87/255 (34%), Gaps = 44/255 (17%)

Query: 903  SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 957
            S   L+        H+  +  R    L  +      G+   LA+++P RK +       G
Sbjct: 139  SSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLG 198

Query: 958  PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 1005
            P   +  A A          G   L   +P  S P G    +  AA + H L    A   
Sbjct: 199  PKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLL--QAARP 256

Query: 1006 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1054
            + Q +RP    +P     P      GLG      P   RP  A     L           
Sbjct: 257  QAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313

Query: 1055 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1110
             +P S + G    AP   QPP A+T  GP       S+    G   PA+V S  R  P  
Sbjct: 314  QIPESAIQGGELGAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHS 366

Query: 1111 KPPVPSSLASVPDPH 1125
             P +P++ A     H
Sbjct: 367  TPCLPTAQACTMSHH 381


>gi|113419951 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 63/255 (24%), Positives = 87/255 (34%), Gaps = 44/255 (17%)

Query: 903  SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 957
            S   L+        H+  +  R    L  +      G+   LA+++P RK +       G
Sbjct: 139  SSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLG 198

Query: 958  PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 1005
            P   +  A A          G   L   +P  S P G    +  AA + H L    A   
Sbjct: 199  PKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLL--QAARP 256

Query: 1006 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1054
            + Q +RP    +P     P      GLG      P   RP  A     L           
Sbjct: 257  QAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLKFPKKPRLGPF 313

Query: 1055 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1110
             +P S + G    APG  QPP A+T  GP       S+    G   PA+V S     P  
Sbjct: 314  QIPESAIQGGELGAPGNLQPPPAATELGP-------STSPQMGRRTPAQVPSVDWQPPHS 366

Query: 1111 KPPVPSSLASVPDPH 1125
             P +P++ A     H
Sbjct: 367  TPCLPTAQACTMSHH 381


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.131    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,225,942
Number of Sequences: 37866
Number of extensions: 2338967
Number of successful extensions: 17873
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 661
Number of HSP's that attempted gapping in prelim test: 14830
Number of HSP's gapped (non-prelim): 3051
length of query: 1242
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1128
effective length of database: 13,930,794
effective search space: 15713935632
effective search space used: 15713935632
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.