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Search of human proteins with 55956784
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956784 spindle assembly associated Sfi1 homolog isoform b
[Homo sapiens]
(1211 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956784 spindle assembly associated Sfi1 homolog isoform b [... 2489 0.0
gi|55956786 spindle assembly associated Sfi1 homolog isoform a [... 2473 0.0
gi|91208420 bassoon protein [Homo sapiens] 50 1e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 1e-05
gi|24308223 hypothetical protein LOC57577 [Homo sapiens] 49 3e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 49 4e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 48 5e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 1e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 47 1e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 47 1e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 47 1e-04
gi|51466800 PREDICTED: hypothetical protein [Homo sapiens] 46 2e-04
gi|169172766 PREDICTED: hypothetical protein LOC389630 [Homo sap... 46 2e-04
gi|89027871 PREDICTED: hypothetical protein [Homo sapiens] 45 3e-04
gi|89027820 PREDICTED: hypothetical protein [Homo sapiens] 45 3e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 4e-04
gi|51466907 PREDICTED: hypothetical protein [Homo sapiens] 45 4e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 45 4e-04
gi|126116596 asp (abnormal spindle)-like, microcephaly associate... 45 5e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 45 5e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 45 5e-04
gi|51466802 PREDICTED: hypothetical protein [Homo sapiens] 44 0.001
gi|148746195 trichohyalin [Homo sapiens] 44 0.001
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 44 0.001
gi|211971097 hypothetical protein LOC441317 [Homo sapiens] 44 0.001
gi|169173146 PREDICTED: hypothetical protein [Homo sapiens] 44 0.001
gi|239742272 PREDICTED: hypothetical protein XP_002342469 isofor... 44 0.001
gi|239742270 PREDICTED: hypothetical protein XP_002342468 isofor... 44 0.001
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 43 0.002
gi|51466913 PREDICTED: hypothetical protein [Homo sapiens] 43 0.002
>gi|55956784 spindle assembly associated Sfi1 homolog isoform b [Homo
sapiens]
Length = 1211
Score = 2489 bits (6452), Expect = 0.0
Identities = 1211/1211 (100%), Positives = 1211/1211 (100%)
Query: 1 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
Sbjct: 1 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60
Query: 61 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120
ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
Sbjct: 61 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120
Query: 121 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180
LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
Sbjct: 121 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180
Query: 181 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240
HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
Sbjct: 181 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240
Query: 241 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300
HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
Sbjct: 241 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300
Query: 301 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360
RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
Sbjct: 301 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360
Query: 361 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA 420
HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA
Sbjct: 361 HYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIA 420
Query: 421 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT 480
LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT
Sbjct: 421 LLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARAT 480
Query: 481 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE 540
RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE
Sbjct: 481 RFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE 540
Query: 541 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL 600
WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL
Sbjct: 541 WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLAL 600
Query: 601 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW 660
RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW
Sbjct: 601 RGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRW 660
Query: 661 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR 720
KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR
Sbjct: 661 KENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWEAQKVLDR 720
Query: 721 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS 780
GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS
Sbjct: 721 GCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS 780
Query: 781 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK 840
TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK
Sbjct: 781 TQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKK 840
Query: 841 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK 900
ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK
Sbjct: 841 ARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWK 900
Query: 901 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA 960
QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA
Sbjct: 901 QKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAA 960
Query: 961 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP 1020
EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP
Sbjct: 961 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP 1020
Query: 1021 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK 1080
TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK
Sbjct: 1021 TALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK 1080
Query: 1081 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW 1140
PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW
Sbjct: 1081 PPVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLW 1140
Query: 1141 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV 1200
SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV
Sbjct: 1141 SCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACV 1200
Query: 1201 ARIQALRQALC 1211
ARIQALRQALC
Sbjct: 1201 ARIQALRQALC 1211
>gi|55956786 spindle assembly associated Sfi1 homolog isoform a [Homo
sapiens]
Length = 1242
Score = 2473 bits (6410), Expect = 0.0
Identities = 1211/1242 (97%), Positives = 1211/1242 (97%), Gaps = 31/1242 (2%)
Query: 1 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60
MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR
Sbjct: 1 MKNLLTEKCISSHNFHQKVIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRR 60
Query: 61 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120
ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL
Sbjct: 61 ELPSTSHLVQYRGTHTCTRQGRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRL 120
Query: 121 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180
LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV
Sbjct: 121 LRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEV 180
Query: 181 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240
HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL
Sbjct: 181 HDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRAL 240
Query: 241 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300
HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR
Sbjct: 241 HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVR 300
Query: 301 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360
RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK
Sbjct: 301 RVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWK 360
Query: 361 HYMLLCAEEAAQFEMAEEHHRHSQL-------------------------------LLHR 389
HYMLLCAEEAAQFEMAEEHHRHSQL LLHR
Sbjct: 361 HYMLLCAEEAAQFEMAEEHHRHSQLYFCFRALKDNVTHAHLQQIRRNLAHQQHGVTLLHR 420
Query: 390 FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH 449
FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH
Sbjct: 421 FWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGH 480
Query: 450 FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE 509
FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE
Sbjct: 481 FQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAE 540
Query: 510 RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR 569
RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR
Sbjct: 541 RMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWRESAQGLR 600
Query: 570 TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT 629
TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT
Sbjct: 601 TERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVT 660
Query: 630 YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV 689
YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV
Sbjct: 661 YQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKV 720
Query: 690 LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ 749
LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ
Sbjct: 721 LVQWREAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQ 780
Query: 750 HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA 809
HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA
Sbjct: 781 HHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRA 840
Query: 810 TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM 869
TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM
Sbjct: 841 TVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASM 900
Query: 870 KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL 929
KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL
Sbjct: 901 KASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPLL 960
Query: 930 NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ 989
NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ
Sbjct: 961 NRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQ 1020
Query: 990 SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP 1049
SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP
Sbjct: 1021 SQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGP 1080
Query: 1050 ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG 1109
ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG
Sbjct: 1081 ELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPG 1140
Query: 1110 LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ 1169
LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ
Sbjct: 1141 LSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQ 1200
Query: 1170 QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC 1211
QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC
Sbjct: 1201 QVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALRQALC 1242
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 50.4 bits (119), Expect = 1e-05
Identities = 65/239 (27%), Positives = 98/239 (41%), Gaps = 38/239 (15%)
Query: 980 RPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTR-PFLAEAPTALVPHSPL-PGALSSAP 1037
+P +L P +P G G+ SLTR P +A P PL P L P
Sbjct: 2211 QPASVLRPMVRGGMYRPYASG-GITAVPLTSLTRVPMIA-------PRVPLGPTGLYRYP 2262
Query: 1038 GPKQPPTAST-----GPELLLLPLSSFMPCGAAAPARVSAQRATPRDKP----------- 1081
P + P AS+ GP L P ++ P GA P+R R++P
Sbjct: 2263 APSRFPIASSVPPAEGPVYLGKPAAAKAP-GAGGPSRPEMPVGAAREEPLPTTTPAAIKE 2321
Query: 1082 ----PVPSSLASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQ 1137
P P+ LA P PG S + PG + E + ++ Q+QLL + +
Sbjct: 2322 AAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEERQRKQ-QEQLLQLERERV 2380
Query: 1138 NLWSCRRQASSLRRWLELNREEPGPEDQEVEQQ--VQKELEQVEMQIQLLAEELQAQRQ 1194
L R+ LR EL RE + E+Q VQ+EL++++ + ++ Q +RQ
Sbjct: 2381 ELEKLRQ----LRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQ 2435
Score = 36.2 bits (82), Expect = 0.19
Identities = 44/150 (29%), Positives = 69/150 (46%), Gaps = 17/150 (11%)
Query: 934 AGAGDGTLETK-RPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQR 992
A +G L++K PQA L GR AA P + + + S+R+ P A S++
Sbjct: 3728 AHSGPAALQSKAEPQAQPQLQ--GRQAAPGP---QQSQSPSSRQIP-------SGAASRQ 3775
Query: 993 PQ-KPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTASTGPEL 1051
PQ + Q+ GLG+ QP +LT+ L + S P A A P+ P+ +TGP+
Sbjct: 3776 PQTQQQQQGLGL-QPPQQALTQARLQQQSQPTTRGSA-PAASQPAGKPQPGPSTATGPQP 3833
Query: 1052 LLLPLSSFMPCGAAAPARVSAQRATPRDKP 1081
P + G+ A+ Q P+ +P
Sbjct: 3834 AGPPRAE-QTNGSKGTAKAPQQGRAPQAQP 3862
Score = 34.7 bits (78), Expect = 0.57
Identities = 37/118 (31%), Positives = 47/118 (39%), Gaps = 17/118 (14%)
Query: 961 EEPHALELNTAHSARKQPRRPHFLLEPAQ--SQRPQKPQEHGLGMAQPAAPSLTRPFLAE 1018
++ H+ L+ AHS KQP L +P Q S+ P PQ A S+ P A
Sbjct: 240 QQLHSPALSPAHSPAKQP-----LGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAA 294
Query: 1019 APTALVPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRAT 1076
AP + SP P P P +P TA P P S A PA + A T
Sbjct: 295 APPEVGRVSPQP------PQPTKPSTAEPRPPAGEAPAKS----ATAVPAGLGATEQT 342
Score = 32.3 bits (72), Expect = 2.8
Identities = 34/121 (28%), Positives = 46/121 (38%), Gaps = 13/121 (10%)
Query: 936 AGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPH-FLLEPAQSQRPQ 994
A G+ PQA L A GR A E+P L + QP R + + + P
Sbjct: 1426 ANYGSQTEDLPQAPSGLAAAGRAAREKP--LSASDGEGGTPQPSRAYSYFASSSPPLSPS 1483
Query: 995 KPQEHGLGMAQPAAPSLTRPFLAE----APTALVPHSPLPGALSSAP----GPKQPPTAS 1046
P E P T F + AP + +P S PGA + +P G + P S
Sbjct: 1484 SPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRS--PGAPTPSPMVAQGTQTPHRPS 1541
Query: 1047 T 1047
T
Sbjct: 1542 T 1542
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 50.1 bits (118), Expect = 1e-05
Identities = 98/588 (16%), Positives = 219/588 (37%), Gaps = 91/588 (15%)
Query: 230 RLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRF 289
+L + R L + L LQ +A +E +Q K+ + V+ ++ W +
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKE----LQSVSAKLQAQVEENELWNR--- 293
Query: 290 LKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQA-WERRESLYAHHAQVEKLAR 348
L Q ++ RQ+ ++ E W++ E+ E + ++ +
Sbjct: 294 ----LNQQQEEKMWRQEEKIQE--------------WEEKIQEQEEKIREQEEKIREQEE 335
Query: 349 KMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLP 408
KM R+ W+ + +E +E E+ R +++ W + + +++ E++
Sbjct: 336 KMR-RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM-------WEKEEKMRRQEEMM- 386
Query: 409 LLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRW 468
W+ K EL + ++ + ++ + R + +++ W
Sbjct: 387 -----WEKEE-----KIRELEEKMHEQEKIREQEEKRQE---EEKIREQEKRQEQEAKMW 433
Query: 469 RHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMW 528
R +E + R E + +Q +WRQ+ H + ++ E E MW
Sbjct: 434 RQEEKI------REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE--------MW 479
Query: 529 HQQAAARHQEQEWQTVACAHHRHGRLKK-AFCLWRESAQGLRTERTGRVRAAE---FHMA 584
Q+ QE+ W+ H + +++K +WR+ + E+ ++R E +
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK--IREQEEKIREQEEKMWRQE 537
Query: 585 QLLRWAWSQWRECLALRGAERQKLMRAD-LHHQHSVLHRALQAWVTYQGRVRSILREVAA 643
+ +R WRE + E++K+ + Q + R + + +V +E
Sbjct: 538 EKIREQEEMWREEEKMH--EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR--QEEKI 593
Query: 644 RESQHNRQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYY 703
RE + RQ + WK+ R E K Q R K+ Q +
Sbjct: 594 REQEEKRQ--EQEEKMWKQEEKIREQEEK--IQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 704 RQQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQL---ERAVQHHHRQLLLEGL 760
+QE+ + +K+ ++ + W + +Q ++ E ++ + +
Sbjct: 650 GEQEEKMCEQEEKMQEQE------ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 703
Query: 761 ARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQR 808
W+ C ++ + Q +++ R + W Q++ R+QE++
Sbjct: 704 KMWEQEEKMCEQEEKMQEQE-----EKMRRQEEKMWEQEVRLRQQEEK 746
Score = 35.4 bits (80), Expect = 0.33
Identities = 55/379 (14%), Positives = 145/379 (38%), Gaps = 37/379 (9%)
Query: 165 VRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWW 224
+R+Q+E R + ++ + +++ Q K W + K++ Q + +++
Sbjct: 406 IREQEEKRQE--EEKIREQEKRQEQEAKMWR-----QEEKIREQEEKIREQEK------- 451
Query: 225 STWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWR-EQLLYVQKEKQKVVSAVKHHQH 283
WRQ +H K R + + WR E+ ++ Q+E + + +
Sbjct: 452 KMWRQE-------EKIHEQE-KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE 503
Query: 284 WQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQV 343
+++ K W Q +++ Q+ ++ E+ + + + ++ W E ++
Sbjct: 504 KIRKQEEKVWR---QEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
Query: 344 EKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKE 403
E+ R+ + W+ + +E + E+ + + +W+ + + +++
Sbjct: 561 EEEKRQ---EQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
Query: 404 RELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWN 463
E + +I + I + TQ++ K Q +++ W
Sbjct: 618 EEKIQE-----QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 464 RLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYR 523
+ + R QE + + + + +++ +KM++ E + + E ++ +
Sbjct: 673 QEEKIREQEKKIREQEEKIREQ---EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 729
Query: 524 SWFMWHQQAAARHQEQEWQ 542
MW Q+ R QE++ Q
Sbjct: 730 EEKMWEQEVRLRQQEEKMQ 748
>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
Length = 936
Score = 48.9 bits (115), Expect = 3e-05
Identities = 63/281 (22%), Positives = 120/281 (42%), Gaps = 19/281 (6%)
Query: 21 KQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCTRQ 80
KQ M + ++ A+++ + L+ KK +L + Q R Q
Sbjct: 649 KQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQ 708
Query: 81 GRLRELRIRCVARKFLYLWIRMTFGRVFPSKARFYYEQRLLRKV-FEEWKEEWWVFQHEW 139
+ R K L R+ + + A+ +YE+ LLRK E WK Q +
Sbjct: 709 LERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKR--LRMQSKQ 766
Query: 140 KLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVV 199
+ V A+ HY +L TW + R Q+ + K +A+ ++ +++ +SWL YV+
Sbjct: 767 NIQV-AEEHYSLFLQRKYMLTW--FQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVI 823
Query: 200 VRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRV-SRALHASALKHRALSLQVQAWS 258
+ +++ + F Q+ I R W++ R +V++ S+ H A +H +
Sbjct: 824 --DLQEEVRKFCVHFLQKKIFRAWFNMVR----EVKIDSQGKHEIAAEHSDRRILWITLR 877
Query: 259 QWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQV 299
W++ + ++++E+ VK + Q RR + L QV
Sbjct: 878 TWKKFVKFMKEER------VKEERRQQLRRKVVEILPDFQV 912
Score = 39.3 bits (90), Expect = 0.023
Identities = 43/209 (20%), Positives = 93/209 (44%), Gaps = 21/209 (10%)
Query: 246 KHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQ-------HWQKRRFLKAWLEYLQ 298
K A + Q + E+ L KE +K ++ Q H+++ K LE +
Sbjct: 699 KREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWK 758
Query: 299 VRRVKRQQN-EMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFT 357
R++ +QN ++AE + + + + Y W Q +ESL AQ ++ ++ L+R
Sbjct: 759 RLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQ--RSQESLARKMAQADQFYSQILLKRVIQ 816
Query: 358 HWKHYMLLCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRS-QIEQKKERELLPLLHAAWDH 416
W Y++ EE +F + H + + ++N+ R +I+ + + E+ A +H
Sbjct: 817 SWLQYVIDLQEEVRKFCV----HFLQKKIFRAWFNMVREVKIDSQGKHEI------AAEH 866
Query: 417 YRIALLCKCIELWLQYTQKRRYKQLLQAR 445
+L + W ++ + + +++ + R
Sbjct: 867 SDRRILWITLRTWKKFVKFMKEERVKEER 895
Score = 37.7 bits (86), Expect = 0.067
Identities = 39/171 (22%), Positives = 75/171 (43%), Gaps = 16/171 (9%)
Query: 735 RRSAQQRLQLERAVQHHHRQLLL--EGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTC 792
++ ++ QLE + H+ ++LL +GL WK +Q + + + L QR
Sbjct: 727 QKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLT 786
Query: 793 FRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQG 852
+ Q Q+ AR+ Q A F++ L +V +WL +V++ LQ ++ +
Sbjct: 787 WFQRSQESLARKMAQ-----ADQFYSQILLKRVIQSWLQYVID-------LQEEVRKFCV 834
Query: 853 QLLQEGATRLLRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKV 903
LQ+ R + ++ + Q + ++ A HS R + WK+ V
Sbjct: 835 HFLQKKIFR--AWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFV 883
Score = 35.4 bits (80), Expect = 0.33
Identities = 50/214 (23%), Positives = 88/214 (41%), Gaps = 23/214 (10%)
Query: 501 QHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRL-KKAFC 559
Q RE E E + L + + Q+ R+Q+ E +A H+ L KK
Sbjct: 698 QKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLE--AIAKEHYERVLLRKKGLE 755
Query: 560 LWRESAQGLRTERTGRVRAAEFHMAQLLR----WAWSQW-RECLALRGAERQKLMRADLH 614
W+ LR + ++ AE H + L+ W Q +E LA +K+ +AD
Sbjct: 756 PWKR----LRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLA------RKMAQADQF 805
Query: 615 HQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRGALRRWKENTMARVDEAKKT 674
+ +L R +Q+W+ Y ++ +R+ Q +++ R +E ++D K
Sbjct: 806 YSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQ--KKIFRAWFNMVRE---VKIDSQGKH 860
Query: 675 FQASTHYRRTICSKVLVQWREAVSVQMYYRQQED 708
A+ H R I L W++ V R +E+
Sbjct: 861 EIAAEHSDRRILWITLRTWKKFVKFMKEERVKEE 894
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 48.5 bits (114), Expect = 4e-05
Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 1/124 (0%)
Query: 986 EPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTA 1045
+P Q P PQ H P ++P +A+ P P A SSAP P PPT+
Sbjct: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP-PATPPTS 139
Query: 1046 STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATR 1105
P P + P +AP P P P P +PG +
Sbjct: 140 GAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPK 199
Query: 1106 AGPG 1109
GPG
Sbjct: 200 QGPG 203
Score = 33.9 bits (76), Expect = 0.96
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 728 QRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQS-----TQ 782
QRW QQR Q+E+ ++ +L E + H +R+ L+ RQ +
Sbjct: 492 QRWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLRQDLMRRQEELRRMEE 551
Query: 783 LLAQRLSRTCFRQWRQQLAARRQEQRATVR 812
L Q + + Q RQ+ RR+E+ +R
Sbjct: 552 LHNQEMQKRKEMQLRQEEERRRREEEMMIR 581
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 48.1 bits (113), Expect = 5e-05
Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 23/190 (12%)
Query: 908 GKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALE 967
G P+P + P + EGP + + A + + P A R A G L + P +
Sbjct: 179 GLPRPAPSARP--RPPTEGP--RKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRS 232
Query: 968 LNTAHSARKQPRR--PHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVP 1025
L+++ + P R P P P +P+ GL +P P +T P AP
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP--PQVTPPRKDAAPAL--- 287
Query: 1026 HSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPS 1085
PL + + P P PP+ S P L LP + PA +Q T P + +
Sbjct: 288 -GPLSSSPLATPSPSAPPSPSAPPSLQTLP---------SPPATPPSQATTSLGSPTLQA 337
Query: 1086 SLASVPDPHL 1095
+ + +P P L
Sbjct: 338 THSFLPSPPL 347
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/157 (29%), Positives = 60/157 (38%), Gaps = 13/157 (8%)
Query: 946 PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQ 1005
P AS PL L + + P+AL ++ + P P P Q+ P P
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQA--PFSPPASPPVSPS 424
Query: 1006 PAAPSLTRPFLAEAPTALVPHSPL--PGALSSAPGPKQPPTASTGPELLLLPLSSFMPCG 1063
PS P LA P + P P P + S+ P P+ PP + P L P P
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484
Query: 1064 AAAP--ARVSAQRATPRDKPPVPSSLASVPDPHLLLP 1098
A P A S + P P PS AS+P L P
Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPS--ASLPMSPLATP 519
Score = 37.7 bits (86), Expect = 0.067
Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 8/119 (6%)
Query: 981 PHFLLEPAQS--QRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPG 1038
P L P Q+ P P L P AP+ L +AP + P P+ S
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418
Query: 1039 PKQPPTA---STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPV---PSSLASVP 1091
P P+A S P L P P A+P + P+ PP+ P LA P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477
Score = 35.8 bits (81), Expect = 0.25
Identities = 51/217 (23%), Positives = 66/217 (30%), Gaps = 45/217 (20%)
Query: 946 PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEH------ 999
P AS P+ + P L A+ P+ P L P P P
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 1000 ----GLGMAQPAAPSLTRPFLAEAPTALVPHSP-------------LPG----------A 1032
L M+ A P P + AP VP SP PG
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 565
Query: 1033 LSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRD----KPPVPSSLA 1088
L+ APGP PP+ S L L+ + P + + P PP + LA
Sbjct: 566 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 625
Query: 1089 SV--------PDPHLLLPGDFSATRAGPGLSTAGSLD 1117
+ P P L G A P + GS D
Sbjct: 626 ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662
Score = 33.5 bits (75), Expect = 1.3
Identities = 56/209 (26%), Positives = 80/209 (38%), Gaps = 30/209 (14%)
Query: 917 APSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALG-RLAAEEPHALELNT----- 970
AP K T GP+ + G GT RP PLG G R++AEE A T
Sbjct: 94 APPAKNTSPGPVSS---PGRASGTT---RPG---PLGQKGLRISAEETVARGKATEAPKR 144
Query: 971 ---AHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHS 1027
+ AR+ P R + +G+ +PA + RP E P V +
Sbjct: 145 SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPRKSVSSA 203
Query: 1028 PLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGA---AAPARVS-AQRATPR----D 1079
+P ++ P+A G L P S + A ++PAR + R TPR
Sbjct: 204 SEHSTTEPSPAARRRPSAGGG---LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 260
Query: 1080 KPPVPSSLASVPDPHLLLPGDFSATRAGP 1108
P P L ++ P + P +A GP
Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGP 289
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 46.6 bits (109), Expect = 1e-04
Identities = 98/593 (16%), Positives = 215/593 (36%), Gaps = 94/593 (15%)
Query: 258 SQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVK----RQQNEMAERF 313
++ +E+L + EK ++ VK + +R K L +Q ++ RQ+ E+ E+
Sbjct: 190 AELQEKLRLAESEKSEIQLNVKELKRKLERA--KFLLPQVQTNTLQEEMWRQEEELREQE 247
Query: 314 HHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQF 373
+ + ++ W + E L ++ + KM RR + E+ +
Sbjct: 248 KKIRKQE------EKMWRQEERLREQEGKMREQEEKM--RRQEKRLREQEKELREQEKEL 299
Query: 374 EMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYT 433
++ + + + +W + + +++ E + W LW Q
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKM------WRQEE--------RLWEQEK 345
Query: 434 QKRRYKQLLQARADGHFQQ----RALPAAFHTWNRLW----------RWRHQENVL--SA 477
Q R +Q ++ + + ++Q R ++W R R +E +
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEE 405
Query: 478 RATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQ 537
R E ++KQ ++W Q+ + ++ RL E+ L + ++ + +W Q+ R Q
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465
Query: 538 EQEWQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQ---- 593
E+ W G+ KK +WR+ E+ ++ E M + W Q
Sbjct: 466 EEMW----------GQEKK---MWRQEKM---REQEDQMWEQEEKMRDQEQKMWDQEERM 509
Query: 594 WRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLL 653
W + LR E + + + Q + + T + ++ +E RE + R+
Sbjct: 510 WEQDERLREKEERMREQKKMWQQEEKMREEKK---TQEQEKKTWDQEEKMREEERMRERE 566
Query: 654 RGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWE 713
+ + +E M R E K Q + + + E + Q Q+++ +WE
Sbjct: 567 K---KMREEEEMMREQEEKMQEQ----------EEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 714 AQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRK 773
++ + W Q D + + + E +Q ++ W+ ++
Sbjct: 614 QEE-------KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM-------WEQEEKMREQE 659
Query: 774 RLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVW 826
+ Q ++ Q + Q + +EQ +R + + K+W
Sbjct: 660 EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 46.6 bits (109), Expect = 1e-04
Identities = 66/236 (27%), Positives = 90/236 (38%), Gaps = 38/236 (16%)
Query: 907 GGKPQPLAAIAPSRKVTFEGPLLNRIAA---GAGDGTLETKRPQASRPLGALGRLAAEEP 963
G P P +A + ++ GP + A G+ + +PQA A P
Sbjct: 192 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP---------TAPVP 242
Query: 964 HALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-QPAAPSLTRPFL-AEAPT 1021
H ++P PH P P P + G A QP+APS +P L + P
Sbjct: 243 HTHIQQAPALHPQRPPSPH----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 298
Query: 1022 ALVPHSPLPGALSSAPGPKQ----PPTASTGPELL-LLPLSSFMPCGAAAPARVSA--QR 1074
PHS G L PGP Q PP AS G L P +++ PA SA +
Sbjct: 299 G--PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 356
Query: 1075 ATPRDKPPVPSSLA--------SVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAEL 1122
PR++P P+ LA + P P L P A + P LS + A L
Sbjct: 357 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP---QAHKHPPHLSGPSPFSMNANL 409
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 46.6 bits (109), Expect = 1e-04
Identities = 66/236 (27%), Positives = 90/236 (38%), Gaps = 38/236 (16%)
Query: 907 GGKPQPLAAIAPSRKVTFEGPLLNRIAA---GAGDGTLETKRPQASRPLGALGRLAAEEP 963
G P P +A + ++ GP + A G+ + +PQA A P
Sbjct: 746 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP---------TAPVP 796
Query: 964 HALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-QPAAPSLTRPFL-AEAPT 1021
H ++P PH P P P + G A QP+APS +P L + P
Sbjct: 797 HTHIQQAPALHPQRPPSPH----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Query: 1022 ALVPHSPLPGALSSAPGPKQ----PPTASTGPELL-LLPLSSFMPCGAAAPARVSA--QR 1074
PHS G L PGP Q PP AS G L P +++ PA SA +
Sbjct: 853 G--PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910
Query: 1075 ATPRDKPPVPSSLA--------SVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAEL 1122
PR++P P+ LA + P P L P A + P LS + A L
Sbjct: 911 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP---QAHKHPPHLSGPSPFSMNANL 963
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 46.6 bits (109), Expect = 1e-04
Identities = 66/236 (27%), Positives = 90/236 (38%), Gaps = 38/236 (16%)
Query: 907 GGKPQPLAAIAPSRKVTFEGPLLNRIAA---GAGDGTLETKRPQASRPLGALGRLAAEEP 963
G P P +A + ++ GP + A G+ + +PQA A P
Sbjct: 746 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAP---------TAPVP 796
Query: 964 HALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-QPAAPSLTRPFL-AEAPT 1021
H ++P PH P P P + G A QP+APS +P L + P
Sbjct: 797 HTHIQQAPALHPQRPPSPH----PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP 852
Query: 1022 ALVPHSPLPGALSSAPGPKQ----PPTASTGPELL-LLPLSSFMPCGAAAPARVSA--QR 1074
PHS G L PGP Q PP AS G L P +++ PA SA +
Sbjct: 853 G--PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQ 910
Query: 1075 ATPRDKPPVPSSLA--------SVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAEL 1122
PR++P P+ LA + P P L P A + P LS + A L
Sbjct: 911 QPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP---QAHKHPPHLSGPSPFSMNANL 963
>gi|51466800 PREDICTED: hypothetical protein [Homo sapiens]
Length = 464
Score = 46.2 bits (108), Expect = 2e-04
Identities = 62/241 (25%), Positives = 86/241 (35%), Gaps = 44/241 (18%)
Query: 886 HSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----GPLLNRIAAGA---- 936
H+ + R L + G+ LA+++P RK + GP + A A
Sbjct: 153 HTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQ 212
Query: 937 ------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSARKQPRRPHFLLEPA 988
G L +P SRP G + AA + H L A + Q +RP +P
Sbjct: 213 PAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLL--QAARPQAQDKRPAVTSQPC 270
Query: 989 QSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL------------VPHSPLPGALSSA 1036
P GLG P RP A L +P S + G A
Sbjct: 271 P---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGA 327
Query: 1037 PGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRDKPPVPSSLASVPDP 1093
P QPP A+T GP S+ G PA+V S R P +P +P++ A
Sbjct: 328 PENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSH 380
Query: 1094 H 1094
H
Sbjct: 381 H 381
>gi|169172766 PREDICTED: hypothetical protein LOC389630 [Homo sapiens]
Length = 464
Score = 46.2 bits (108), Expect = 2e-04
Identities = 62/241 (25%), Positives = 86/241 (35%), Gaps = 44/241 (18%)
Query: 886 HSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----GPLLNRIAAGA---- 936
H+ + R L + G+ LA+++P RK + GP + A A
Sbjct: 153 HTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQ 212
Query: 937 ------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSARKQPRRPHFLLEPA 988
G L +P SRP G + AA + H L A + Q +RP +P
Sbjct: 213 PAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLL--QAARPQAQDKRPAVTSQPC 270
Query: 989 QSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL------------VPHSPLPGALSSA 1036
P GLG P RP A L +P S + G A
Sbjct: 271 P---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGA 327
Query: 1037 PGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRDKPPVPSSLASVPDP 1093
P QPP A+T GP S+ G PA+V S R P +P +P++ A
Sbjct: 328 PENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSH 380
Query: 1094 H 1094
H
Sbjct: 381 H 381
>gi|89027871 PREDICTED: hypothetical protein [Homo sapiens]
Length = 464
Score = 45.4 bits (106), Expect = 3e-04
Identities = 64/255 (25%), Positives = 88/255 (34%), Gaps = 44/255 (17%)
Query: 872 SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 926
S L+ H+ + R L + G+ LA+++P RK + G
Sbjct: 139 SSDYLRVASGPMPVHTSSKRPRLDPILADRSATAMSGRGSVLASLSPLRKASLSSSSSLG 198
Query: 927 PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 974
P + A A G L +P SRP G + AA + H L A
Sbjct: 199 PKERQTGAAADMPQPAVRHEGREPLLVVKPTHSRPEGGCREVPQAASKTHGLP--QAARP 256
Query: 975 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1023
+ Q +RP P P GLG P RP A L
Sbjct: 257 QAQDKRPAVTSLPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313
Query: 1024 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1079
+P S + G AP QPP A+T GP S+ G PA+V S R P
Sbjct: 314 QIPESAIQGGELGAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHS 366
Query: 1080 KPPVPSSLASVPDPH 1094
+P +P++ A H
Sbjct: 367 RPCLPTAQACTMSHH 381
>gi|89027820 PREDICTED: hypothetical protein [Homo sapiens]
Length = 464
Score = 45.4 bits (106), Expect = 3e-04
Identities = 62/241 (25%), Positives = 86/241 (35%), Gaps = 44/241 (18%)
Query: 886 HSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----GPLLNRIAAGA---- 936
H+ + R L + G+ LA+++P RK + GP + A A
Sbjct: 153 HTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQ 212
Query: 937 ------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSARKQPRRPHFLLEPA 988
G L +P SRP G + AA + H L A + Q +RP +P
Sbjct: 213 PAVRHQGREPLLVVKPTHSRPEGDCREVPQAASKTHGLL--QAARPQAQDKRPAVTSQPC 270
Query: 989 QSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL------------VPHSPLPGALSSA 1036
P GLG P RP A L +P S + G A
Sbjct: 271 P---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGA 327
Query: 1037 PGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRDKPPVPSSLASVPDP 1093
P QPP A+T GP S+ G PA+V S R P +P +P++ A
Sbjct: 328 PENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSH 380
Query: 1094 H 1094
H
Sbjct: 381 H 381
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/300 (15%), Positives = 123/300 (41%), Gaps = 28/300 (9%)
Query: 251 SLQVQAWSQ---WREQLLYVQKEKQKV---VSAVKHHQHWQKRRFLKAWLEYLQVRRVKR 304
+LQ + W Q REQ ++K+++K+ ++ + + + K W Q +R++
Sbjct: 269 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWR---QEKRLRE 325
Query: 305 QQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYML 364
Q+ E+ E+ + + +Q E+ E ++ ++ + KM W+
Sbjct: 326 QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM--------WR---- 373
Query: 365 LCAEEAAQFEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCK 424
+E +E ++ Q + + +W +++ E + W+ ++ + +
Sbjct: 374 ---QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE--QVEKMRE 428
Query: 425 CIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWR--WRHQENVLSARATRF 482
++ Q + R ++ +Q +++ + T + +EN+ +
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488
Query: 483 HRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQ 542
++ L +Q LW Q+ Q +E ++ E+ + + ++ + MW Q+ ++Q W+
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548
Score = 37.0 bits (84), Expect = 0.11
Identities = 81/486 (16%), Positives = 185/486 (38%), Gaps = 71/486 (14%)
Query: 117 EQRLLRKVFEEWKE-EWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKY 175
EQ+ LR+ E+ +E E +++ E K+ + + +R +++ K Q+Q+MR++
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE--ERLWEQEKQMREQEQKMRDQE 396
Query: 176 IRA-----EVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQR 230
R + + +++MR+ K W +R K +MQ + R + R+R
Sbjct: 397 ERMWEQDERLREKEERMREQEKMWEQVEKMREEK-KMQEQEKKTRDQEEKMQEEERIRER 455
Query: 231 LGQVRVSRAL---HASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQH--WQ 285
++R ++ + ++ Q +W++Q L QKEK ++ + W+
Sbjct: 456 EKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE 515
Query: 286 KRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQA-WERRESLYAHHAQVE 344
+ ++ E + +Q +M E+ + + D +Q W++ E + + E
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 345 KLA----------RKMALRRAFTHWKHYMLLCAEEAAQ-------------FEMAEEHHR 381
K +M R + M+ EE Q +E E+
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635
Query: 382 HSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQL 441
+ + + +W + + +++ L W+H ++ K E + ++ + ++
Sbjct: 636 QEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKK 695
Query: 442 LQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHR--ETLEKQVFSLWRQ-- 497
Q + + Q + R + R +E ++ + + E +++Q +W Q
Sbjct: 696 TQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755
Query: 498 KMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKA 557
KM++ E MW QQ +E+ W+ H ++++
Sbjct: 756 KMWEQEEK---------------------MWEQQRLPEQKEKLWE--------HEKMQEQ 786
Query: 558 FCLWRE 563
+W +
Sbjct: 787 EKIWEQ 792
>gi|51466907 PREDICTED: hypothetical protein [Homo sapiens]
Length = 464
Score = 45.1 bits (105), Expect = 4e-04
Identities = 64/255 (25%), Positives = 88/255 (34%), Gaps = 44/255 (17%)
Query: 872 SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 926
S L+ H+ + R L + G+ LA+++P RK + G
Sbjct: 139 SSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLG 198
Query: 927 PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 974
P + A A G L +P SRP G + AA + H L A
Sbjct: 199 PKERQTGAAADIPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLL--QAARP 256
Query: 975 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1023
+ Q +RP +P P GLG P RP A L
Sbjct: 257 QAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313
Query: 1024 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1079
+P S + G AP QPP A+T GP S+ G PA+V S R P
Sbjct: 314 QIPESAIQGGELGAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSIDRQPPHS 366
Query: 1080 KPPVPSSLASVPDPH 1094
P +P++ A H
Sbjct: 367 TPCLPTAQACTMSHH 381
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 45.1 bits (105), Expect = 4e-04
Identities = 186/843 (22%), Positives = 305/843 (36%), Gaps = 148/843 (17%)
Query: 437 RYKQLLQARADGHFQQRALPAAFHTWNRLWRWR-----------HQENVLSARATRFH-- 483
R ++L QAR + Q AL A L + + LS ATR
Sbjct: 846 REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLE 905
Query: 484 RETLEKQVFSLWRQ--KMFQHRENRLAERMAILHAERQLL-----YRSWFMWHQQAAARH 536
+E LE +F + RQ ++ RE AE A+L A+ L R + Q+ A+
Sbjct: 906 KEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLD 965
Query: 537 QEQEWQTVACAHHR-HGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWR 595
+E Q + A L++ E Q L+ E+ R E AQL +
Sbjct: 966 KELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQE 1025
Query: 596 ECLALRGAERQKLMR--ADLHHQHS----VLHRALQAWVTYQGRVRSILREVAARESQHN 649
E LA AE+++L A L + + Q ++ + ++ L E ++H+
Sbjct: 1026 ELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSE-KLMGTRHS 1084
Query: 650 RQLLRGALRRWKENTMARVDEAKKTFQASTHYRRTICSK----VLVQWREAVSVQMYYR- 704
+ + R K + +R ++ + T A T R + ++ +E +Q R
Sbjct: 1085 LATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARD 1144
Query: 705 --QQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHH--RQLLLEGL 760
+Q D + EA++ LRT + D ++ L+ +R ++ R++ +
Sbjct: 1145 LGKQRDSCLREAEE------LRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA 1198
Query: 761 ARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFS 820
+ + ++R R+S + L + + + +LA +EQ+ + A
Sbjct: 1199 GELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVG 1258
Query: 821 LQAKVWATWLAFV----LERRRK--------------KARLQWALQAYQGQL-LQEGAT- 860
+A T L V LE RR+ RL L QG+L L E A
Sbjct: 1259 KEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEK 1318
Query: 861 -----------RLLRFAASMKASRQQLQ-AQQQVQAAHSLHRAVRRCATLWKQKVLGRGG 908
RLL+ AS++ RQ+LQ AQ+++Q R R L RG
Sbjct: 1319 ESRRETLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRER--RLLGSLEEARGT 1376
Query: 909 KPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALG-RLAAEEPHALE 967
+ Q L A G LE K A LG RL+A E A
Sbjct: 1377 EKQQLDH-----------------ARG-----LELKLEAARAEAAELGLRLSAAEGRAQG 1414
Query: 968 LNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHS 1027
L A AR + +R AQ + GLG+ + +P+ RP VP S
Sbjct: 1415 LE-AELARVEVQR---RAAEAQLGGLRSALRRGLGLGRAPSPA-PRP---------VPGS 1460
Query: 1028 PLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSL 1087
P A + G G +P S +P +PP P
Sbjct: 1461 PARDAPAEGSGE-----------------------GLNSP---STLECSPGSQPPSPGPA 1494
Query: 1088 ASVPDPHLLLPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQAS 1147
S P L D A R + E +E++ Q + + R A+
Sbjct: 1495 TSPASPDL----DPEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSAT 1550
Query: 1148 SLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQIQLLAEELQAQRQPIGACVARIQALR 1207
S R L ++ E +E + V L V+ ++ L E ++ + A + ++ L
Sbjct: 1551 SRARQL----QKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLE 1606
Query: 1208 QAL 1210
++L
Sbjct: 1607 RSL 1609
>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
[Homo sapiens]
Length = 3477
Score = 44.7 bits (104), Expect = 5e-04
Identities = 187/982 (19%), Positives = 370/982 (37%), Gaps = 230/982 (23%)
Query: 19 VIKQRMEKKVDSRYFKDGAVKKPYSAKTLSNKKSSASFGIRRELPSTSHLVQYRGTHTCT 78
VI+Q+ + ++ + +++ +SA L A+F R + + HL + T
Sbjct: 2363 VIQQQYQANRAAKLQRQHYLRQRHSAVILQ-----AAF---RGMKTRRHLKSMHSSATLI 2414
Query: 79 RQGRLREL--RIRCVARKFLYLWIRMTFGRVFPSKARFY---------------YEQRLL 121
Q R R L R R ++ K ++++ + +K + Y Y + ++
Sbjct: 2415 -QSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMV 2473
Query: 122 RKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQQEMRNKYIRAEVH 181
+K +E + + V +R Y + FQTWK Q+ Y A++
Sbjct: 2474 KKKLQEMQ----------RAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYRAAKLQ 2523
Query: 182 DAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALH 241
++ + W S ++ + Q + + I+++ + +RQ ++ A
Sbjct: 2524 --RENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATK 2581
Query: 242 ASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRR 301
K+RA K+KQKV H +K ++A + + +++
Sbjct: 2582 IIQEKYRA------------------NKKKQKVFQ----HNELKKETCVQAGFQDMNIKK 2619
Query: 302 VKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKH 361
++Q H ++ C +A++ R+ A V + R+ R T +
Sbjct: 2620 QIQEQ-------HQAAIIIQKHC---KAFKIRKHYLHLRATVVSIQRRY---RKLTAVRT 2666
Query: 362 YMLLCAEEAAQ-FEMAEE--HHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYR 418
++C + + F++ ++ + + L+ F+ + R++++ + ++ + ++ ++YR
Sbjct: 2667 QAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQ---NYYR 2723
Query: 419 IALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSAR 478
+ + K T+++ + + ++ R + AAF
Sbjct: 2724 LYVRVK--------TERKNFLAVQKS-------VRTIQAAFRGMKV-------------- 2754
Query: 479 ATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQE 538
RQK+ E ++A AI++ YRS + +
Sbjct: 2755 -----------------RQKLKNVSEEKMA---AIVNQSALCCYRSKTQYEAVQSEGVMI 2794
Query: 539 QEWQT---VACA----HHRHGR----LKKAFCLWRESAQGLRTERTGRVRAAEF-HMAQL 586
QEW +AC+ +H R ++KAFC R + L T++ +R F MA
Sbjct: 2795 QEWYKASGLACSQEAEYHSQSRAAVTIQKAFC--RMVTRKLETQKCAALRIQFFLQMAVY 2852
Query: 587 LRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARES 646
R Q R + L Q R + +L+R +A V Q R+ L +
Sbjct: 2853 RRRFVQQKRAAITL-----QHYFRTWQTRKQFLLYR--KAAVVLQNHYRAFL------SA 2899
Query: 647 QHNRQL---LRGALRRWKENTMARVDEAK------KTFQASTHYRRTICSKVLVQWREAV 697
+H RQ+ +R ++ + + + + K T + +RR K L + + A
Sbjct: 2900 KHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAAC 2959
Query: 698 SVQMYYR----QQEDCAIWEAQKVLDRGCLRTWFQRWWDCSRRSA------QQRLQLERA 747
+Q +YR +E AI +A K++ +GC T +R + R++ + R L
Sbjct: 2960 KIQAWYRCWRAHKEYLAILKAVKII-QGCFYTKLERTRFLNVRASAIIIQRKWRAILPAK 3018
Query: 748 VQHHHRQLLLEGLARWKTHHLQCV----------RKRLLHRQSTQLLAQRLSR------- 790
+ H H ++ K H C+ R+ L ++S L+ Q+ R
Sbjct: 3019 IAHEHFLMI-------KRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKH 3071
Query: 791 ----------------TCFRQWRQQLAARRQEQRATVRALWFWA---FSLQA----KVWA 827
R W + R EQRA +R L F A + L A + +
Sbjct: 3072 ERIKYIEFKKSTVILQALVRGW--LVRKRFLEQRAKIRLLHFTAAAYYHLNAVRIQRAYK 3129
Query: 828 TWLAFVLERRRKKARLQWALQAYQGQLLQEGATRLLRFAASMKASRQQLQ--AQQQVQAA 885
+LA ++ K+ +Q + LQE R ++ S+K + Q Q+ +AA
Sbjct: 3130 LYLA--VKNANKQVNSVICIQRWFRARLQE--KRFIQKYHSIKKIEHEGQECLSQRNRAA 3185
Query: 886 HSLHRAVRRCATLWKQKVLGRG 907
+ +AVR KQ+ G
Sbjct: 3186 SVIQKAVRHFLLRKKQEKFTSG 3207
Score = 32.0 bits (71), Expect = 3.7
Identities = 54/239 (22%), Positives = 93/239 (38%), Gaps = 45/239 (18%)
Query: 141 LCVRA-DCHYRYYLYNLMFQTWKTYV-------RQQQEMRNKYIRAEVHD--AKQKMRQA 190
LC R D L+ TW+ Y Q++E + I+ V + AKQ++R+
Sbjct: 1256 LCARLLDLRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKR 1315
Query: 191 WKSWLIY------VVVRRTKLQMQTTALEFRQRIILRVWWSTWRQRLGQVRVSRALHASA 244
+ L+ V+ +R L ++ LE Q + WR R S
Sbjct: 1316 VNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWR------RYSTRQRFLK 1369
Query: 245 LKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHW----------QKRRFLKAWL 294
LK+ ++ LQ + ++ V K+ + + V +HW Q+ LK+
Sbjct: 1370 LKYYSIILQSRI-----RMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSST 1424
Query: 295 EYLQVRRVKRQQNEMAERFHHVTVLQIYFCDW---QQAWERR-----ESLYAHHAQVEK 345
+Q K +Q +M + +LQ F +W +QA E +S Y H ++ K
Sbjct: 1425 LIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRK 1483
Score = 31.2 bits (69), Expect = 6.3
Identities = 114/637 (17%), Positives = 239/637 (37%), Gaps = 95/637 (14%)
Query: 165 VRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIILRVWW 224
+R ++ +++ + A A KM Q S + Y +R+ + +Q + Q + R +
Sbjct: 2107 IRVRRHIQHMHRAATFIKAMFKMHQ---SRISYHTMRKAAIVIQVRCRAYYQGKMQREKY 2163
Query: 225 STWRQRLGQVRVS----RALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKH 280
T + + ++ S R A +L + ++R+Q + K K ++
Sbjct: 2164 LTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYF---NKLKKITKTVQ 2220
Query: 281 HQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQIYFCDWQQAWERRESLYAHH 340
++W + + Y ++R H V +Q F ++A + ++
Sbjct: 2221 QRYWAMKERNIQFQRYNKLR-------------HSVIYIQAIFRG-KKARRHLKMMHIAA 2266
Query: 341 AQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHRHSQL--LLHRFWNLWRSQI 398
+++ R + +RR F K +L + + H + Q+ + + + +R +
Sbjct: 2267 TLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWM 2326
Query: 399 EQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQARADGHFQQRALPAA 458
+K+ RE+ +R A + + + RY+ L QA Q +A AA
Sbjct: 2327 IRKRMREM----------HRAATFIQ--STFRMHRLHMRYQALKQASVVIQQQYQANRAA 2374
Query: 459 FHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHRENRLAERMAILHAER 518
R RH +L A + K +H ++ + I R
Sbjct: 2375 KLQRQHYLRQRHSAVILQA---------------AFRGMKTRRHLKSMHSSATLIQSRFR 2419
Query: 519 QLLYRSWFMWHQQAAARHQEQEWQTVACAH--HRHGRLKKAFCLWRESAQGLRTERTGRV 576
LL R F+ ++A Q + T+ H ++ L+KA + S + L ++
Sbjct: 2420 SLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKK---- 2475
Query: 577 RAAEFHMAQLLRWA-WSQWRECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVR 635
+ E A +L A + +R + + + + L QH +RA +
Sbjct: 2476 KLQEMQRAAVLIQATFRMYRTYITFQTWKHASI----LIQQHYRTYRAAK---------- 2521
Query: 636 SILREVAARESQHNRQLLRGALRRWKENTMARVD-EAKKTFQASTHYRRTICSKVLVQWR 694
+ RE R+ H+ +++ A + K + R +A Q++ R C +QW
Sbjct: 2522 -LQRENYIRQ-WHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWA 2579
Query: 695 EAVSVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQRWWDCS-RRSAQQRLQLERAVQHHHR 753
+ + Y ++ +++ ++ C++ FQ D + ++ Q++ Q +Q H +
Sbjct: 2580 TKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQ---DMNIKKQIQEQHQAAIIIQKHCK 2636
Query: 754 QLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSR 790
+RK LH ++T + QR R
Sbjct: 2637 AFK--------------IRKHYLHLRATVVSIQRRYR 2659
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 44.7 bits (104), Expect = 5e-04
Identities = 55/176 (31%), Positives = 73/176 (41%), Gaps = 26/176 (14%)
Query: 946 PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQ 1005
P AS PL L + + P+AL ++ + P P P Q+ P P +
Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQA--PFSPPA-----SP 683
Query: 1006 PAAPSLTRPFLA----EAPTALVPHSP---LPGALSSAPGPKQPPTASTGPELL--LLPL 1056
P +PS T P A AP VP SP P + S+ P P+ PP + P + P
Sbjct: 684 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 1057 SSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLST 1112
S M A P RV A P + P PS AS+P L P +A P L+T
Sbjct: 744 SPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLPMSPLAKP----PPQAPPALAT 794
Score = 43.9 bits (102), Expect = 0.001
Identities = 58/234 (24%), Positives = 88/234 (37%), Gaps = 39/234 (16%)
Query: 908 GKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALE 967
G P+P + P + EGP + + A + + P A R A G L + P +
Sbjct: 188 GLPRPAPSARP--RPPTEGP--RKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRS 241
Query: 968 LNTAHSARKQPRR--PHFLLEPAQSQRPQKPQEHGLGMAQP---------AAPSL----T 1012
L+++ + P R P P P +P+ GL +P AAP+L +
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 1013 RPFLAEAPTAL----VPH-----SPLPGALSSAPG-----PKQPPTASTGPELLLLPLSS 1058
P +P+ VP +PLP L +P P PP+ S P L LP
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 1059 FMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLST 1112
P A P+ + P PP ++ + PH L A + LS+
Sbjct: 362 ATPPSQAPPSMTT----PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
Score = 39.7 bits (91), Expect = 0.018
Identities = 41/127 (32%), Positives = 52/127 (40%), Gaps = 10/127 (7%)
Query: 973 SARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSP---L 1029
SA P+ P L P P P M+ A P P L AP VP SP L
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPP--MSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 1030 PGALSSAPGPKQPPTASTGP-ELLLLPLSSF---MPCGAAAPARVSAQRATPRDKPPV-P 1084
P + + P P+ PP +T P + L P +SF P +A +S P PPV
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
Query: 1085 SSLASVP 1091
+ L VP
Sbjct: 837 APLLQVP 843
Score = 38.9 bits (89), Expect = 0.030
Identities = 31/116 (26%), Positives = 42/116 (36%), Gaps = 5/116 (4%)
Query: 981 PHFLLEPAQS--QRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPG 1038
P L P Q+ P P L P AP+ L +AP + P P+ S
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682
Query: 1039 PKQPPTA---STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVP 1091
P P+A S P L P P A+P + P+ PP+ + VP
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738
Score = 36.2 bits (82), Expect = 0.19
Identities = 52/172 (30%), Positives = 56/172 (32%), Gaps = 25/172 (14%)
Query: 946 PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQK-----PQEHG 1000
P PL AL LA+ P A S P L P Q P P E+
Sbjct: 483 PLTIHPLQALSSLASHSPQA----PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538
Query: 1001 LGMAQP----AAPSLTRPFLAEAPTAL-----VPHSPL----PGALSS-APGPKQPPTAS 1046
+A P A+ LT P L P P SPL P SS A P Q P A
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598
Query: 1047 TGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLP 1098
P L LP P P P PP P AS P L P
Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP--ASPPLSPLATP 648
Score = 34.3 bits (77), Expect = 0.74
Identities = 47/202 (23%), Positives = 67/202 (33%), Gaps = 33/202 (16%)
Query: 946 PQASRPLGALGRLAAEEPHALELNTAHSARKQPRR----------PHFLLEPAQSQRPQK 995
P AS P+ L + + P AL + P + P + PQ
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 831
Query: 996 PQEHGLGMAQ-----PAAPSLTRPFLAEAPTALVPHSPLPG---ALSSAPGPKQPPTAST 1047
P + Q PA+P+L P P P + + G L+ APGP PP+ S
Sbjct: 832 PPVLAAPLLQVPPSPPASPTLQAP---RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Query: 1048 GPELLLLPLSSFMPCGAAAPARVSAQRATPRD----KPPVPSSLASV--------PDPHL 1095
L L+ + P + + P PP + LA+ P P L
Sbjct: 889 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948
Query: 1096 LLPGDFSATRAGPGLSTAGSLD 1117
G A P + GS D
Sbjct: 949 AFRGAPGAPLPWPPATGPGSAD 970
Score = 30.8 bits (68), Expect = 8.2
Identities = 56/205 (27%), Positives = 72/205 (35%), Gaps = 26/205 (12%)
Query: 909 KPQPLAA-----IAPSRKVTFE--GPLLNR-IAAGAGDGTLETKRP---QASRPLGALGR 957
KP+ L A + P RK GPL + +A + GT P A+ PL A
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT-- 330
Query: 958 LAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLA 1017
L P A L A + P L P + Q P M P P P L
Sbjct: 331 LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS----MTTP--PMQAPPSLQ 384
Query: 1018 EAPTALVPHSPLPGALSSAPGPK-----QPPTASTGPELLLLPLSSFMPCGAAAPARVSA 1072
P VPHS +L + P P Q T+ P L M + S
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
Query: 1073 QR--ATPRDKPPVPSSLASVPDPHL 1095
R +TP D PP+ + L+ P L
Sbjct: 445 SRPASTPPDSPPLQAPLSLPASPPL 469
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 44.7 bits (104), Expect = 5e-04
Identities = 91/381 (23%), Positives = 141/381 (37%), Gaps = 68/381 (17%)
Query: 873 RQQLQAQQQVQAAHSLHRAV------RRCATLWKQKVLGRGGKPQ--PLAAIAPSRKVTF 924
+QQ Q QQQ Q HS A+ R L Q + G G +P P A ++T
Sbjct: 3600 QQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTP 3659
Query: 925 EGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLAAEE----PHALELNTA--------- 971
G L G T ++ Q GA G LA P L L +
Sbjct: 3660 GGMALPGQPGGPFLNTALAQQQQQQHSGGA-GSLAGPSGGFFPGNLALRSLGPDSRLLQE 3718
Query: 972 HSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMA-----QPAAPSL-TRPFLAEAPTALVP 1025
+ Q +R + Q Q+ Q+ Q+H LG Q P + T L P L+P
Sbjct: 3719 RQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMP 3778
Query: 1026 HSPLPGALSS--APGPKQPPTASTGP-ELLLLPLSSFMPCGAAAPAR------------- 1069
S G L +P P Q P GP ++ +L G P R
Sbjct: 3779 PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSP 3838
Query: 1070 --------------VSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAGPGLSTA-- 1113
V+AQ+ + + S+A + L + P LS
Sbjct: 3839 QLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSH----LQQSLMSHSGQPKLSAQPM 3894
Query: 1114 GSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQK 1173
GSL + +++QQQ Q +Q L +Q L++ +++ Q+ +QQ+Q+
Sbjct: 3895 GSLQQLQQQQQLQQQQQLQQQQQQQL----QQQQQLQQQQLQQQQQQQQLQQQQQQQLQQ 3950
Query: 1174 ELEQVEMQIQLLAEELQAQRQ 1194
+ +Q++ Q Q ++ Q Q+Q
Sbjct: 3951 QQQQLQQQQQQQQQQFQQQQQ 3971
Score = 41.6 bits (96), Expect = 0.005
Identities = 49/184 (26%), Positives = 70/184 (38%), Gaps = 17/184 (9%)
Query: 943 TKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPA--QSQRPQKPQEHG 1000
T P LGA R A +P + R QP P L+P P+ G
Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262
Query: 1001 LGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQ---PPTASTGPELLLLPLS 1057
+G + + P L+ P E+ AL GA S + GP + S+G L L L
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELK 2322
Query: 1058 SFMPCGAAAPARVSAQRATPR--------DKPPVPSSLASVPDPH--LLLPGDFSATRAG 1107
+ P AP A + P+ +PP +LA P H + PG ++ A
Sbjct: 2323 T--PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ 2380
Query: 1108 PGLS 1111
P L+
Sbjct: 2381 PPLT 2384
Score = 38.5 bits (88), Expect = 0.039
Identities = 37/146 (25%), Positives = 48/146 (32%), Gaps = 11/146 (7%)
Query: 961 EEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAP 1020
EEPH + QP H + + +P+E L P RP E P
Sbjct: 811 EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP---EKP 867
Query: 1021 TALVPHSPLPGALSSAPGPKQP--------PTASTGPELLLLPLSSFMPCGAAAPARVSA 1072
P P L P P +P P S E L PL +P + +S
Sbjct: 868 PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSP 927
Query: 1073 QRATPRDKPPVPSSLASVPDPHLLLP 1098
Q P PP S + + P L P
Sbjct: 928 QLMPPDPLPPPLSPIITAAAPPALSP 953
Score = 37.4 bits (85), Expect = 0.087
Identities = 69/259 (26%), Positives = 91/259 (35%), Gaps = 37/259 (14%)
Query: 869 MKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFEGPL 928
++ +QQL QQQ AA S+ A+ LGR PLA I+ GP
Sbjct: 2810 LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGIS----TRLPGP- 2864
Query: 929 LNRIAAGAGDGTLETKRPQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPA 988
+ AG R + LG G T + P+RP F
Sbjct: 2865 GEPVPGPAGPAQFIELRHNVQKGLGPGG-------------TPFPGQGPPQRPRFY---P 2908
Query: 989 QSQRPQKPQEHGL-GMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPTAST 1047
S+ P + GL G+A P P AP P L +L P K PT T
Sbjct: 2909 VSEDPHRLAPEGLRGLAVSGLP----PQKPSAP----PAPELNNSLHPTPHTK-GPTLPT 2959
Query: 1048 GPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVPDPHLLLPGDFSATRAG 1107
G EL+ P SS G P + A + P + P + D H L D G
Sbjct: 2960 GLELVNRPPSS-TELGRPNPLALEAGK-LPCEDPELDDDF----DAHKALEDDEELAHLG 3013
Query: 1108 PGLSTAGSLDLEAELEEIQ 1126
G+ A D LE ++
Sbjct: 3014 LGVDVAKGDDELGTLENLE 3032
Score = 34.3 bits (77), Expect = 0.74
Identities = 77/341 (22%), Positives = 131/341 (38%), Gaps = 58/341 (17%)
Query: 743 QLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAA 802
Q ++ Q H +Q + GL+ HLQ + + H +L AQ + Q +QQL
Sbjct: 3856 QQQQQQQQHQQQGSMAGLS-----HLQ--QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQ 3908
Query: 803 RRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQAYQGQLLQEGATRL 862
++Q Q+ + L Q ++ L ++++ + + Q LQ Q QL Q+ +
Sbjct: 3909 QQQLQQQQQQQL-----QQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQ 3963
Query: 863 LRFAASMKASRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPL------AAI 916
+F QQ Q QQQ+ + + +Q LG G +PL A+
Sbjct: 3964 QQF--------QQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGAL 4015
Query: 917 APSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPL--GALGRLAAEEPHALELNTAHSA 974
P+ +T G N + E PL G A EP ++ + + +
Sbjct: 4016 GPTLLLT--GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDS 4073
Query: 975 -------RKQPRRPHFLLEPAQSQRPQKPQE-----------HG-LGMAQPAAPSLTRPF 1015
+ QP+ L+P Q+ Q+ HG LG + S
Sbjct: 4074 QLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHL 4133
Query: 1016 LAEAPTALVPHSPLPGALS-SAPGPKQPPTA-----STGPE 1050
LA+ +L PG+++ + GP+QP +TGP+
Sbjct: 4134 LAQPSVSL---GDQPGSMTQNLLGPQQPMLERPMQNNTGPQ 4171
Score = 33.5 bits (75), Expect = 1.3
Identities = 49/205 (23%), Positives = 78/205 (38%), Gaps = 11/205 (5%)
Query: 985 LEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF----LAEAPTALVPHSPLPGALSSAPGPK 1040
L P + P E L A+P L+ PF L+ P L P SP P A +P P+
Sbjct: 520 LSPPEESPPSPALETPLSPPPEASP-LSPPFEESPLSPPPEEL-PTSPPPEASRLSPPPE 577
Query: 1041 QPPTASTGPELLLLP---LSSFMPCGAAAPARVSAQRATPRDKPPVPSSLASVP-DPHLL 1096
+ P + E + P S P +P + +P PP S L+ P D +
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE-SPLSPPPEASRLSPPPEDSPMS 636
Query: 1097 LPGDFSATRAGPGLSTAGSLDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELN 1156
P + S P +S L + + L ++ +++ S +AS L E +
Sbjct: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS 696
Query: 1157 REEPGPEDQEVEQQVQKELEQVEMQ 1181
P PED + L + ++
Sbjct: 697 PTSPPPEDSPASPPPEDSLMSLPLE 721
Score = 32.3 bits (72), Expect = 2.8
Identities = 49/177 (27%), Positives = 68/177 (38%), Gaps = 13/177 (7%)
Query: 909 KPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASR-PLGALGRLAAEEPHALE 967
K + L A +PS G ++ ++G G LE K P + PL R + EP +
Sbjct: 2288 KKEELGASSPSYGPPNLG-FVDSPSSGTHLGGLELKTPDVFKAPLTP--RASQVEPQSPG 2344
Query: 968 LNTAHSARKQPRRPHFLLEPAQSQRPQ--KPQEHGLGMAQPAAPSLTRPFLAEAPTALVP 1025
L R Q P L P+ P +P + AQP +P E+ AL P
Sbjct: 2345 LGL----RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400
Query: 1026 HSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPP 1082
S S P Q ++S P L PLS+ C +P Q P +PP
Sbjct: 2401 RSLPSDPFSRVPASPQSQSSSQSP-LTPRPLSAEAFC--PSPVTPRFQSPDPYSRPP 2454
Score = 30.8 bits (68), Expect = 8.2
Identities = 29/119 (24%), Positives = 44/119 (36%), Gaps = 7/119 (5%)
Query: 985 LEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPGPKQPPT 1044
L P + P P L +++P S P E+P + P S L + P PP
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES--PLSPPE 524
Query: 1045 ASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRDK-----PPVPSSLASVPDPHLLLP 1098
S L PLS +P + + P ++ PP S L+ P+ + P
Sbjct: 525 ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583
>gi|51466802 PREDICTED: hypothetical protein [Homo sapiens]
Length = 464
Score = 43.9 bits (102), Expect = 0.001
Identities = 58/214 (27%), Positives = 78/214 (36%), Gaps = 44/214 (20%)
Query: 913 LAAIAPSRKVTFE-----GPLLNRIAAGA----------GDGTLETKRPQASRPLGALGR 957
LA+++P RK + GP + A A G L +P SRP G
Sbjct: 180 LASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCRE 239
Query: 958 L--AAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF 1015
+ AA + H L A + Q +RP +P P GLG P RP
Sbjct: 240 VPQAASKTHGLL--QAARPQAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPA 294
Query: 1016 LAEAPTAL------------VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMP 1061
A L +P S + G AP QPP A+T GP S+
Sbjct: 295 QAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGP-------STSPQ 347
Query: 1062 CGAAAPARV-SAQRATPRDKPPVPSSLASVPDPH 1094
G PA+V S R P +P +P++ A H
Sbjct: 348 MGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHH 381
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.9 bits (102), Expect = 0.001
Identities = 126/575 (21%), Positives = 214/575 (37%), Gaps = 71/575 (12%)
Query: 327 QQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLL---CAEEAAQFEMAEEHHRHS 383
++ W++R+ + Q+E+ +K A RR + LL E+ + E +
Sbjct: 1283 RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEE 1342
Query: 384 QLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQLLQ 443
QLL R R Q +K RE L H K +E + ++ R ++ L+
Sbjct: 1343 QLLQEREEQPLRRQERDRKFRE-EELRHQEQGR-------KFLEEEQRLRRQERERKFLK 1394
Query: 444 ARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQHR 503
Q+R +R +R Q+ R +F E E+QV R++ F
Sbjct: 1395 EEQQLRCQEREQQLR-QDRDRKFREEEQQLSRQERDRKFREE--EQQVRRQERERKFLEE 1451
Query: 504 ENRL-AERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLWR 562
E +L ER E QLL QE+E Q + HR R +K
Sbjct: 1452 EQQLRQERHRKFREEEQLL---------------QEREEQQL----HRQERDRK---FLE 1489
Query: 563 ESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSVLHR 622
E Q R ER + R E + R + ++ RQ+ R L + L R
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ------LHRQQRQRKFLQEEQQ-LRR 1542
Query: 623 ALQAWVTYQGRVRSILREVAARESQHNRQLL---RGALRRWKENTMARVDEAKKTFQAST 679
+ Q R R E R+ + +QL R R +E + R ++ +K +
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 680 HYRRTICSKVLVQWREAV-----------SVQMYYRQQEDCAIWEAQKVLDRGCLRTWFQ 728
RR + L Q R+ Q +RQ+ D E + L R +
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 729 RWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRLLHRQSTQLLAQRL 788
D R +Q LQ + +QL + R Q +R++ R+ Q Q
Sbjct: 1663 HDRDRKFREEEQLLQ-----EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717
Query: 789 SRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWLAFVLERRRKKARLQWALQ 848
+ R++R++ R++ ++ +R + L+ + ER ++ R Q +
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP------EREEQQLRRQERDR 1771
Query: 849 AY--QGQLLQEGATRLLRFAASMKASRQQLQAQQQ 881
+ + QL QE + LR S + R++ Q +Q+
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Score = 43.5 bits (101), Expect = 0.001
Identities = 121/584 (20%), Positives = 215/584 (36%), Gaps = 99/584 (16%)
Query: 253 QVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAER 312
Q+++ + R+ +Y + KQ+ + + +KRR ++ L++ + R RQQ E +R
Sbjct: 707 QLESEADARQSKVYSRPRKQE--GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Query: 313 FHHVTVLQIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQ 372
D+ W+ E ++L+ + LR + Q
Sbjct: 765 -----------RDFTWQWQAEEK---SERGRQRLSARPPLRE-------------QRERQ 797
Query: 373 FEMAEEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQY 432
E R + L R + +++E+EL L +
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE------------------EQ 839
Query: 433 TQKRRYKQLLQARADG-HFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQV 491
Q+R Q LQ DG Q + ++ WRW+ +E R T + + L++Q+
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 492 FSLWRQKMFQHRENRL--AERMAILHAERQLLYR---------SWFMWHQQAAARHQEQE 540
Q++ Q E L ER E++ YR + ++ R QE+E
Sbjct: 900 RK--EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 541 WQTVACAHHRHGRL--KKAFCLWRESAQGLRTERTGRVRAAE---FHMAQLLRWAWSQWR 595
Q + + +L K+ L E + R ER + R E QLLR + R
Sbjct: 958 RQ-----YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR----EER 1008
Query: 596 ECLALRGAERQKLMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLRG 655
E + ERQ + +L + L R + Q R R E E Q + L G
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE---EELQQEEEQLLG 1065
Query: 656 ALR--RWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWE 713
R R ++ + + ++ Q R K Q RE + QQE+ +
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 714 AQKVLDRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHL--QCV 771
++ R R+ +++ + E VQ QLL E + + L Q
Sbjct: 1126 EEREKRR--------------RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Query: 772 RKRLLHRQSTQLL---AQRLSRTCFRQWRQQLAARRQEQRATVR 812
+ L ++ QLL ++ + RQ+R++ +RQ+++ R
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Score = 42.7 bits (99), Expect = 0.002
Identities = 135/678 (19%), Positives = 249/678 (36%), Gaps = 120/678 (17%)
Query: 261 REQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNE--MAERFHHVTV 318
RE+ L +++E+++ Q ++ + L+ E + +R+KRQ+ E + +R
Sbjct: 485 RERWLKLEEEERR-------EQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ 537
Query: 319 LQIYFCDWQQAWERRESLYAHHAQ--VEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMA 376
L+ ++ ERRE L + +E+ R+ L+R + +L EE Q +
Sbjct: 538 LR------REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 377 EEHHRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKR 436
E + L R + R + E+++E+ L + R L K E ++R
Sbjct: 592 REQEERLEQRLKRE-EVERLEQEERREQRLK---REEPEEERRQQLLKSEE-----QEER 642
Query: 437 RYKQLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSL-- 494
R +QL + + + Q+ + + H+E +E +++ S
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIP 702
Query: 495 ---WR---------QKMFQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQE-- 540
W+ K++ + +R E++ S W ++ A Q+QE
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 541 ------WQTVACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQW 594
WQ A GR + + + LR +R ++RA E + +
Sbjct: 763 QRRDFTWQWQAEEKSERGRQRLS------ARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 595 RECLALRGAERQK-LMRADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLL 653
+E + ER+K L + Q RA Q G + + R SQ R
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG----LQEDQERRRSQEQR--- 869
Query: 654 RGALRRWKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAIWE 713
R RW+ ++E +K R T+ +K +Q + Q+ ++E+ E
Sbjct: 870 RDQKWRWQ------LEEERK------RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 714 AQKVLDRGCLRTWFQRWWDCSRRSAQQR-LQLERAVQHHHRQLLLEGLA--RWKTHHLQC 770
+K RR Q+R + E +Q QLL E R + Q
Sbjct: 918 REK-----------------RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 771 VRKRLLHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAKVWATWL 830
+ + L ++ QLL + + RRQE+ R + ++
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKR-----------RRQEREKKYRE--------EEELQQEEE 1001
Query: 831 AFVLERRRKKARLQWALQAYQGQLLQEGATRLL-------RFAASMKASRQQLQAQQQVQ 883
+ E R K+ R +W Q + LQ+ +LL R + R++ + QQ+ +
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Query: 884 AAHSLHRAVRRCATLWKQ 901
R RR L +Q
Sbjct: 1062 QLLGEERETRRRQELERQ 1079
Score = 40.0 bits (92), Expect = 0.013
Identities = 116/589 (19%), Positives = 217/589 (36%), Gaps = 60/589 (10%)
Query: 261 REQLLYVQKEKQKVVSAVKHHQHWQKRR-FLKAWLEYLQVRRVKRQQNEMAERFHHVTVL 319
RE+ ++E+Q V + + W+KR L+ E LQ +RQ+ E+ E + L
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR-ELQEEEEQLRKL 281
Query: 320 QIYFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEH 379
+ E R Q ++L R+ LRR + Q E E+
Sbjct: 282 E--------RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ--------QEERREQQ 325
Query: 380 HRHSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYK 439
R Q R L R Q E+++++ L + R L + E + Q RR +
Sbjct: 326 ERREQQEERREQQLRREQEERREQQ----LRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 440 QLLQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKM 499
QL + + QQ +L R ++ + + R ++ +Q QK
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQL---RREQQLRREQQLRREQQLRREQEEERHEQK- 437
Query: 500 FQHRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFC 559
H + R +R+ ER R W ++ RH+++ + R ++
Sbjct: 438 --HEQERREQRLKREQEER----RDWLK-REEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 560 LWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSV 619
L E + + R ++R + + R + E L R Q+L R + +
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQ-RLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 620 LHRALQAWVTYQGRVRSILRE-------VAARESQHNRQLLRGALRRWKENTMARVDEAK 672
L R + + + R + + RE + RE + +Q L+ E + R +E +
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR-EEVE 608
Query: 673 KTFQASTHYRRTICSKVLVQWREAV---------SVQMYYRQQEDCAIWEAQKVLDRGCL 723
+ Q +R + + R+ + Q R+Q++ ++ + L
Sbjct: 609 RLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL 668
Query: 724 RTWFQRWWDCSRRSA--------QQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRL 775
+R + RR Q R +++ + QL E AR + + RK+
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR-PRKQE 727
Query: 776 LHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQRATVRALWFWAFSLQAK 824
R+ + +R R QW+++ A RQ+Q R + W + + K
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
Score = 38.5 bits (88), Expect = 0.039
Identities = 75/358 (20%), Positives = 128/358 (35%), Gaps = 59/358 (16%)
Query: 262 EQLLYVQKEKQKVVSAVKHHQHWQKRRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVLQI 321
EQLL ++E+Q H+ + R+FL+ E Q+RR +R+Q +R +
Sbjct: 1625 EQLLQEREEQQL-------HRQERDRKFLE---EEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Query: 322 YFCDWQQAWERRESLYAHHAQVEKLARKMALRRAFTHWKHYMLLCAEEAAQFEMAEEHHR 381
+ ++ RR+ + E+ R+ R F + EE
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF------------------LQEEQQL 1716
Query: 382 HSQLLLHRFWNLWRSQIEQKKERELLPLLHAAWDHYRIALLCKCIELWLQYTQKRRYKQL 441
Q L +F Q+ Q+ E+E L + YR L + + + Q RR ++
Sbjct: 1717 RRQELERKFRE--EEQLRQETEQEQL----RRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 442 LQARADGHFQQRALPAAFHTWNRLWRWRHQENVLSARATRFHRETLEKQVFSLWRQKMFQ 501
+ R + +Q + ++R +E + R + R + W ++ Q
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR-WEEEQLQ 1829
Query: 502 HRENRLAERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTVACAHHRHGRLKKAFCLW 561
L E+ L ER YR+ + Q +R +EQE LW
Sbjct: 1830 -----LEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE-------------------LW 1865
Query: 562 RESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAERQKLMRADLHHQHSV 619
+E Q R ER ++R Q Q E + G +L+ H SV
Sbjct: 1866 QEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASV 1923
Score = 36.6 bits (83), Expect = 0.15
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 1116 LDLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKEL 1175
L E EE +QQLL + ++ R+ RR L REE E++ +EQ++++E
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE---EEERLEQRLKREH 676
Query: 1176 EQVEMQIQLLAEELQAQRQPIGACVARIQ 1204
E+ + +L EE + R+ I + + + Q
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQ 705
Score = 36.6 bits (83), Expect = 0.15
Identities = 152/754 (20%), Positives = 277/754 (36%), Gaps = 103/754 (13%)
Query: 109 PSKARFYYEQRLLRKVFEEWKEEWWVFQHEWKLCVRADCHYRYYLYNLMFQTWKTYVRQQ 168
P K R ++ R+ E +EE + + E + R + +Y + + Q + +R++
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 169 QEMRNKYIRAEVHDAKQKMRQAWKSWL--IYVVVRRTKLQMQTTALEFRQRIILRVWWST 226
+E R R + +++++Q + L RR +L+ Q E Q+ ++
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 227 WRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKHHQHWQK 286
+R Q R + L+ Q EQLL ++EK++ Q+ ++
Sbjct: 1098 PEKRRRQERERQCREEEELQ------------QEEEQLLREEREKRR--RQELERQYREE 1143
Query: 287 RRFLKAWLEYLQVRRVKRQQNEMAERFHHVTVL-----QIYFCDWQQAWERRESLYAHHA 341
+ + L+ KR++ E+ ++ L Q+ + ++ + RE Y
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE 1203
Query: 342 QVEKLARKMALR----RAFTHWK-----------HYMLLCAEEAAQFEMAEEHHRHSQLL 386
++++ RK R R+ W+ + + E QF E+ +
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263
Query: 387 LHRFWNLWRSQIEQKKERELLPLLHAAWDHY-RIALLCKCIELWLQYTQKRR------YK 439
+L Q E+ +E+E W R + +E Q KRR K
Sbjct: 1264 QQDLQHLLGEQQERDREQE-----RRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK 1318
Query: 440 QLLQARADGHFQQRALPAAFHTWNRLWRWRHQENV-LSARATRFHRETL----------- 487
QLL+ + +++ F +L + R ++ + R +F E L
Sbjct: 1319 QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 488 -EKQVFSLWRQKMFQHRENRL--AERMAILHAERQLLYRSWFMWHQQAAARHQEQEWQTV 544
E+++ R++ F E +L ER L +R +R QQ + + ++++++
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE---EEQQLSRQERDRKFREE 1435
Query: 545 ACAHHRHGRLKKAFCLWRESAQGLRTERTGRVRAAEFHMAQLLRWAWSQWRECLALRGAE 604
R R +K + E Q LR ER + R E QLL Q RE L E
Sbjct: 1436 EQQVRRQERERK----FLEEEQQLRQERHRKFREEE----QLL-----QEREEQQLHRQE 1482
Query: 605 RQKLM---RADLHHQHSVLHRALQAWVTYQGRVRSILREVAARESQHNRQLLR--GALRR 659
R + L Q Q + + + + E Q R+ L+ LRR
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 660 WKENTMARVDEAKKTFQASTHYRRTICSKVLVQWREAVSVQMYYRQQEDCAI-WEAQKVL 718
+ R D +K + Q R+ Q RQ+ D E QKV
Sbjct: 1543 QERGQQRRQDRDRKFREEE-------------QLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Query: 719 DRGCLRTWFQRWWDCSRRSAQQRLQLERAVQHHHRQLLLEGLARWKTHHLQCVRKRL--- 775
+ R + + R+ QQ+L+ ER + + LL+ + H + RK L
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE 1649
Query: 776 --LHRQSTQLLAQRLSRTCFRQWRQQLAARRQEQ 807
L RQ + + FR+ Q L ++Q
Sbjct: 1650 PQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Score = 35.4 bits (80), Expect = 0.33
Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 5/81 (6%)
Query: 1119 EAELEEIQQQLLHYQTTKQNLWSCRRQASS----LRRWLELNREEPGPED-QEVEQQVQK 1173
E EL++ ++QLL + K+ RQ + +L REEP QE+E+Q ++
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 1174 ELEQVEMQIQLLAEELQAQRQ 1194
E E + + QLL EE + +RQ
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQ 1193
Score = 34.3 bits (77), Expect = 0.74
Identities = 29/82 (35%), Positives = 44/82 (53%), Gaps = 11/82 (13%)
Query: 1121 ELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEP---GPED-----QEVEQQVQ 1172
EL++ ++QLL + K+ L RQ R EL +EE G E QE+E+Q +
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQ---YREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 1173 KELEQVEMQIQLLAEELQAQRQ 1194
KE E + + QLL EE + +R+
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRR 1103
Score = 33.1 bits (74), Expect = 1.6
Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Query: 1119 EAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQV 1178
E E E +QQL Q ++ RR+ LRR +L RE+ +Q++ ++ Q EQ
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRRE-QQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 1179 EMQIQLLAEELQAQRQ 1194
+ Q L E Q +R+
Sbjct: 413 LRREQQLRREQQLRRE 428
Score = 33.1 bits (74), Expect = 1.6
Identities = 22/77 (28%), Positives = 40/77 (51%)
Query: 1118 LEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQ 1177
L+ E EE + QLL + ++ R Q L + L+ E +++ EQ++++E +
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 1178 VEMQIQLLAEELQAQRQ 1194
E + QLL E Q +R+
Sbjct: 627 EERRQQLLKSEEQEERR 643
Score = 32.3 bits (72), Expect = 2.8
Identities = 21/72 (29%), Positives = 35/72 (48%)
Query: 1123 EEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELEQVEMQI 1182
E +QQL Q ++ RR+ RR +L RE+ +Q++ ++ Q EQ +
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 1183 QLLAEELQAQRQ 1194
Q L E Q +R+
Sbjct: 405 QQLRREQQLRRE 416
Score = 31.6 bits (70), Expect = 4.8
Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 1118 LEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNRE-------EPGPEDQEVEQQ 1170
L E EE ++Q L Q ++ L R LRR E RE E E + EQ+
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 1171 VQKELEQVEMQIQLLAEELQAQR 1193
+++E E+ Q+ EE + QR
Sbjct: 567 LKREQEERRDQLLKREEERRQQR 589
Score = 30.8 bits (68), Expect = 8.2
Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 5/81 (6%)
Query: 1119 EAELEEIQQQLLHYQTT---KQNLWSCRRQASSLRRWLE-LNREEPGPED-QEVEQQVQK 1173
E EL++ ++QLL + +Q L R+ L++ E L REEP QE E+Q ++
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Query: 1174 ELEQVEMQIQLLAEELQAQRQ 1194
E E + + QLL EE + +R+
Sbjct: 1113 EEELQQEEEQLLREEREKRRR 1133
Score = 30.8 bits (68), Expect = 8.2
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 10/82 (12%)
Query: 1117 DLEAELEEIQQQLLHYQTTKQNLWSCRRQASSLRRWLELNREEPGPEDQEVEQQVQKELE 1176
D + + QQ L H +Q R + RRW + R+ PE++++E++ QKE +
Sbjct: 1255 DSQLRDRQSQQDLQHLLGEQQE----RDREQERRRWQQ--RDRHFPEEEQLEREEQKEAK 1308
Query: 1177 ----QVEMQIQLLAEELQAQRQ 1194
+ + + QLL EE + +R+
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRR 1330
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 43.9 bits (102), Expect = 0.001
Identities = 63/218 (28%), Positives = 86/218 (39%), Gaps = 34/218 (15%)
Query: 900 KQKVLGRGGKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALGRLA 959
K++ R Q LA + ++ +G LL R+A+GA + E +R +AS L G
Sbjct: 1076 KERWSKRARPQQDLARLVMEKR---QGRLLLRLASGASSSSSEEQR-RASETLSGTG--- 1128
Query: 960 AEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSL-------T 1012
+EE A RK R A + R + P+ GL M P A
Sbjct: 1129 SEEDTPASEPAAALPRKSGR--------AAATRSRIPRPIGLRMPMPVAAQQPASRSHGA 1180
Query: 1013 RPFLAEAPTALVPHSPLPGALSSAP-GPKQPPTASTGPELLLLPLSSFMPCGAAAPARVS 1071
P L A T+ + PG+ ++A PKQPP GP P PA S
Sbjct: 1181 APALDTAITSRLQLQTPPGSATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTS 1240
Query: 1072 AQR---ATPRD------KPPVPSSLA--SVPDPHLLLP 1098
A R A+PR + P PS A VP P + P
Sbjct: 1241 AARNASASPRSQSLSRRESPSPSHQARPGVPPPRGVPP 1278
>gi|211971097 hypothetical protein LOC441317 [Homo sapiens]
Length = 464
Score = 43.5 bits (101), Expect = 0.001
Identities = 63/255 (24%), Positives = 88/255 (34%), Gaps = 44/255 (17%)
Query: 872 SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 926
S + L+ H+ + R L + G+ LA+++P RK + G
Sbjct: 139 SSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLG 198
Query: 927 PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 974
P + A A G L +P S P G + AA + H L A
Sbjct: 199 PKERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLL--QAVRP 256
Query: 975 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1023
+ Q +RP +P P GLG P RP A L
Sbjct: 257 QAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313
Query: 1024 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1079
+P S + G AP QPP A+T GP S+ G PA+V S R P
Sbjct: 314 QIPESAIQGGELRAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHS 366
Query: 1080 KPPVPSSLASVPDPH 1094
P +P++ A H
Sbjct: 367 TPCLPTAQACTMSHH 381
>gi|169173146 PREDICTED: hypothetical protein [Homo sapiens]
Length = 464
Score = 43.5 bits (101), Expect = 0.001
Identities = 63/255 (24%), Positives = 90/255 (35%), Gaps = 44/255 (17%)
Query: 872 SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 926
S L+ + H+ + +R L + G+ LA+++P RK + G
Sbjct: 139 SSDYLRVARGPMPVHTTSKRLRMDPVLSGRSATEMSGRGSVLASLSPLRKASLSSSSSLG 198
Query: 927 PLLNRIAAGAG----------DGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 974
P + A A TL P S P G+ + AA + H L A
Sbjct: 199 PKERQTGAAADIPRPAVRHQVHETLLVVEPTHSSPEGSCREVPQAASKTHGLL--QAVRT 256
Query: 975 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1023
+ Q +RP +P S GLG P RP A L
Sbjct: 257 QAQDKRPAVTSQPCPSAATHSL---GLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313
Query: 1024 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1079
+P S + G AP QPP A+T GP S G PA+V S +R P
Sbjct: 314 QIPESTIQGGELGAPENLQPPPAATELGP-------SRSPQMGRRTPAQVPSVERQPPHR 366
Query: 1080 KPPVPSSLASVPDPH 1094
+P +P++ A H
Sbjct: 367 RPCLPTAQACTMSHH 381
>gi|239742272 PREDICTED: hypothetical protein XP_002342469 isoform 2
[Homo sapiens]
Length = 464
Score = 43.5 bits (101), Expect = 0.001
Identities = 58/214 (27%), Positives = 79/214 (36%), Gaps = 44/214 (20%)
Query: 913 LAAIAPSRKVTFE-----GPLLNRIAAGA----------GDGTLETKRPQASRPLGALGR 957
LA+++P RK + GP + A A G L +P S P G
Sbjct: 180 LASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSPEGGCRE 239
Query: 958 L--AAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF 1015
+ AA + H L A S + Q +RP +P P GLG P RP
Sbjct: 240 VPQAASKTHGLL--QAISPQAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPA 294
Query: 1016 LAEAPTAL------------VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMP 1061
A L +P S + G AP QPP A+T GP S+
Sbjct: 295 QAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPEYLQPPPATTELGP-------STSPQ 347
Query: 1062 CGAAAPARVSA-QRATPRDKPPVPSSLASVPDPH 1094
G PA+VS+ R P +P +P++ A H
Sbjct: 348 MGRRTPAQVSSVDRQPPHSRPCLPTAQACTMSHH 381
>gi|239742270 PREDICTED: hypothetical protein XP_002342468 isoform 1
[Homo sapiens]
Length = 464
Score = 43.5 bits (101), Expect = 0.001
Identities = 58/214 (27%), Positives = 79/214 (36%), Gaps = 44/214 (20%)
Query: 913 LAAIAPSRKVTFE-----GPLLNRIAAGA----------GDGTLETKRPQASRPLGALGR 957
LA+++P RK + GP + A A G L +P S P G
Sbjct: 180 LASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSPEGGCRE 239
Query: 958 L--AAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPF 1015
+ AA + H L A S + Q +RP +P P GLG P RP
Sbjct: 240 VPQAASKTHGLL--QAISPQAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPA 294
Query: 1016 LAEAPTAL------------VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMP 1061
A L +P S + G AP QPP A+T GP S+
Sbjct: 295 QAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPEYLQPPPATTELGP-------STSPQ 347
Query: 1062 CGAAAPARVSA-QRATPRDKPPVPSSLASVPDPH 1094
G PA+VS+ R P +P +P++ A H
Sbjct: 348 MGRRTPAQVSSVDRQPPHSRPCLPTAQACTMSHH 381
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 43.1 bits (100), Expect = 0.002
Identities = 55/211 (26%), Positives = 79/211 (37%), Gaps = 35/211 (16%)
Query: 908 GKPQPLAAIAPSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPL--GALGRLAAEE--- 962
G P+P + P + EGP + +++ + T E RP G L R A+
Sbjct: 188 GLPRPAPSARP--RPPTEGPRKS-VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 963 ---PHALELNTAHSARKQPRRPHF----------LLEPAQSQRPQKPQEHGLGMAQP--- 1006
P + + SAR PR P L P Q P+K LG
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 1007 AAPSLTRPFLAEAPTAL--VPHSPLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGA 1064
A PS + ++AP L PHS + P P PP+ S P L LP
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP--------- 355
Query: 1065 AAPARVSAQRATPRDKPPVPSSLASVPDPHL 1095
+ PA +Q T P + ++ + +P P L
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPL 386
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/157 (29%), Positives = 60/157 (38%), Gaps = 13/157 (8%)
Query: 946 PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQ 1005
P AS PL L + + P+AL ++ + P P P Q+ P P
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQA--PFSPPASPPVSPS 463
Query: 1006 PAAPSLTRPFLAEAPTALVPHSPL--PGALSSAPGPKQPPTASTGPELLLLPLSSFMPCG 1063
PS P LA P + P P P + S+ P P+ PP + P L P P
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523
Query: 1064 AAAP--ARVSAQRATPRDKPPVPSSLASVPDPHLLLP 1098
A P A S + P P PS AS+P L P
Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPS--ASLPMSPLATP 558
Score = 37.7 bits (86), Expect = 0.067
Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 8/119 (6%)
Query: 981 PHFLLEPAQS--QRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHSPLPGALSSAPG 1038
P L P Q+ P P L P AP+ L +AP + P P+ S
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 1039 PKQPPTA---STGPELLLLPLSSFMPCGAAAPARVSAQRATPRDKPPV---PSSLASVP 1091
P P+A S P L P P A+P + P+ PP+ P LA P
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Score = 35.8 bits (81), Expect = 0.25
Identities = 51/217 (23%), Positives = 66/217 (30%), Gaps = 45/217 (20%)
Query: 946 PQASRPLGALGRLAAEEPHALELNTAHSARKQPRRPHFLLEPAQSQRPQKPQEH------ 999
P AS P+ + P L A+ P+ P L P P P
Sbjct: 485 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 1000 ----GLGMAQPAAPSLTRPFLAEAPTALVPHSP-------------LPG----------A 1032
L M+ A P P + AP VP SP PG
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604
Query: 1033 LSSAPGPKQPPTASTGPELLLLPLSSFMPCGAAAPARVSAQRATPRD----KPPVPSSLA 1088
L+ APGP PP+ S L L+ + P + + P PP + LA
Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 664
Query: 1089 SV--------PDPHLLLPGDFSATRAGPGLSTAGSLD 1117
+ P P L G A P + GS D
Sbjct: 665 ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701
Score = 33.5 bits (75), Expect = 1.3
Identities = 56/209 (26%), Positives = 80/209 (38%), Gaps = 30/209 (14%)
Query: 917 APSRKVTFEGPLLNRIAAGAGDGTLETKRPQASRPLGALG-RLAAEEPHALELNT----- 970
AP K T GP+ + G GT RP PLG G R++AEE A T
Sbjct: 103 APPAKNTSPGPVSS---PGRASGTT---RPG---PLGQKGLRISAEETVARGKATEAPKR 153
Query: 971 ---AHSARKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTALVPHS 1027
+ AR+ P R + +G+ +PA + RP E P V +
Sbjct: 154 SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP-PTEGPRKSVSSA 212
Query: 1028 PLPGALSSAPGPKQPPTASTGPELLLLPLSSFMPCGA---AAPARVS-AQRATPR----D 1079
+P ++ P+A G L P S + A ++PAR + R TPR
Sbjct: 213 SEHSTTEPSPAARRRPSAGGG---LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269
Query: 1080 KPPVPSSLASVPDPHLLLPGDFSATRAGP 1108
P P L ++ P + P +A GP
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGP 298
>gi|51466913 PREDICTED: hypothetical protein [Homo sapiens]
Length = 464
Score = 43.1 bits (100), Expect = 0.002
Identities = 63/255 (24%), Positives = 87/255 (34%), Gaps = 44/255 (17%)
Query: 872 SRQQLQAQQQVQAAHSLHRAVRRCATLWKQKVLGRGGKPQPLAAIAPSRKVTFE-----G 926
S L+ H+ + R L + G+ LA+++P RK + G
Sbjct: 139 SSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLG 198
Query: 927 PLLNRIAAGA----------GDGTLETKRPQASRPLGALGRL--AAEEPHALELNTAHSA 974
P + A A G L +P S P G + AA + H L A
Sbjct: 199 PKERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLL--QAARP 256
Query: 975 RKQPRRPHFLLEPAQSQRPQKPQEHGLGMAQPAAPSLTRPFLAEAPTAL----------- 1023
+ Q +RP +P P GLG P RP A L
Sbjct: 257 QAQDKRPAVTSQPCP---PAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPF 313
Query: 1024 -VPHSPLPGALSSAPGPKQPPTAST--GPELLLLPLSSFMPCGAAAPARV-SAQRATPRD 1079
+P S + G AP QPP A+T GP S+ G PA+V S R P
Sbjct: 314 QIPESAIQGGELGAPENLQPPPAATELGP-------STSPQMGRRTPAQVPSVDRQPPHS 366
Query: 1080 KPPVPSSLASVPDPH 1094
P +P++ A H
Sbjct: 367 TPCLPTAQACTMSHH 381
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.131 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,071,483
Number of Sequences: 37866
Number of extensions: 2288000
Number of successful extensions: 17699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 661
Number of HSP's that attempted gapping in prelim test: 14622
Number of HSP's gapped (non-prelim): 3068
length of query: 1211
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1097
effective length of database: 13,930,794
effective search space: 15282081018
effective search space used: 15282081018
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.