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Search of human proteins with 55770832
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55770832 cerebellar degeneration-related protein 2 [Homo
sapiens]
(454 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55770832 cerebellar degeneration-related protein 2 [Homo sapi... 889 0.0
gi|154759283 cerebellar degeneration-related protein 2-like [Hom... 336 2e-92
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 64 2e-10
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 59 7e-09
gi|55770834 centromere protein F [Homo sapiens] 55 1e-07
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 55 2e-07
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 54 4e-07
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 54 4e-07
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 54 4e-07
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 54 4e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 54 4e-07
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 54 4e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 52 8e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 52 8e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 52 8e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 52 8e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 52 8e-07
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 52 8e-07
gi|118498362 kinectin 1 isoform b [Homo sapiens] 52 1e-06
gi|118498356 kinectin 1 isoform a [Homo sapiens] 52 1e-06
gi|118498368 kinectin 1 isoform c [Homo sapiens] 52 1e-06
gi|33620775 kinectin 1 isoform a [Homo sapiens] 52 1e-06
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 52 1e-06
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 51 2e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 50 3e-06
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 50 3e-06
gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 ... 50 3e-06
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 50 3e-06
gi|116686122 kinesin family member 4 [Homo sapiens] 50 3e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 50 4e-06
>gi|55770832 cerebellar degeneration-related protein 2 [Homo
sapiens]
Length = 454
Score = 889 bits (2296), Expect = 0.0
Identities = 454/454 (100%), Positives = 454/454 (100%)
Query: 1 MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQL 60
MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQL
Sbjct: 1 MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQL 60
Query: 61 QEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIE 120
QEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIE
Sbjct: 61 QEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIE 120
Query: 121 CLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEK 180
CLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEK
Sbjct: 121 CLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEK 180
Query: 181 ITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT 240
ITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT
Sbjct: 181 ITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT 240
Query: 241 GAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPE 300
GAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPE
Sbjct: 241 GAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPE 300
Query: 301 SHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKY 360
SHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKY
Sbjct: 301 SHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKY 360
Query: 361 EELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPP 420
EELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPP
Sbjct: 361 EELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPP 420
Query: 421 EYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS 454
EYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS
Sbjct: 421 EYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS 454
>gi|154759283 cerebellar degeneration-related protein 2-like [Homo
sapiens]
Length = 465
Score = 336 bits (862), Expect = 2e-92
Identities = 204/461 (44%), Positives = 286/461 (62%), Gaps = 22/461 (4%)
Query: 7 VEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYL 66
+E+F +E+E WYD QDL+QDL LAAELGKTLL+RN ELE S+QQMY+TN+EQ+QEIEYL
Sbjct: 7 MEDFSAEEEESWYDQQDLEQDLHLAAELGKTLLERNKELEGSLQQMYSTNEEQVQEIEYL 66
Query: 67 TKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNI 126
TKQ++ LR +NEQHAKVYEQLD+TAR+LE TN +LV +SKA+QQKI LTETIE LQ +
Sbjct: 67 TKQLDTLRHVNEQHAKVYEQLDLTARDLELTNHRLVLESKAAQQKIHGLTETIERLQAQV 126
Query: 127 DHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQG 186
+ LQ+QVE+L+ Q R K ++ + +F CLKEL + F +SL+
Sbjct: 127 EELQAQVEQLRGLEQLRVLREKRERRRTIHTFPCLKELCTSPR---CKDAFRLHSSSLEL 183
Query: 187 QPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRAR 246
P P E+ENE L+ V L++Q+S ERQ++ E EY VL+E SELE+QL A R R
Sbjct: 184 GPRPLEQENERLQTLVGALRSQVSQERQRKERAEREYTAVLQEYSELERQLCEMEACRLR 243
Query: 247 ALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQS-----------LLEEMF 295
ELEAE+ E++QM Q++ ++ G + + ++L P + ++ ++
Sbjct: 244 VQELEAELLELQQMKQAK-TYLLGPDDHLAEALLAPLTQAPEADDPQPGRGDDLGAQDGV 302
Query: 296 LTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSA 355
+ S +++S S+T L+++ D H A +V++RG+S+L EVD QY A
Sbjct: 303 SSPAASPGHVVRKSCSDTALNAIVAKDPASRHAGNLTLHANSVRKRGMSILREVDEQYHA 362
Query: 356 LKVKYEELLKKCQEEQDSLSHKAVQTSR-----AAAKDLTGVNAQSEPVASGWELASVNP 410
L KYEELL KC++ + H VQTSR ++ +DL G V +G + S +
Sbjct: 363 LLEKYEELLSKCRQHGAGVRHAGVQTSRPISRDSSWRDLRGGEEGQGEVKAGEKSLSQHV 422
Query: 411 EPVSS--PTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRS 449
E V + PEYKALFKEIFS I+KTK +I+ + K S
Sbjct: 423 EAVDKRLEQSQPEYKALFKEIFSRIQKTKADINATKVKTHS 463
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 64.3 bits (155), Expect = 2e-10
Identities = 94/456 (20%), Positives = 186/456 (40%), Gaps = 63/456 (13%)
Query: 25 QQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQH---- 80
QQ+ +L AE G E+ QQ+ + + I L++ E L Q ++ H
Sbjct: 445 QQEAKLLAERG--------HFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARL 496
Query: 81 ----AKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEEL 136
A + +L +++ +Q+L + +++K L +T++ + L+ QVE+L
Sbjct: 497 TAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQL 556
Query: 137 KSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENE 196
SS + + LKE+ + ++ DH + T+ + + + E +
Sbjct: 557 SSSLKQKEQQ--------------LKEVAEKQEATRQDHA-QQLATAAEEREASLRERDA 601
Query: 197 HLKKT----------VTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAY--- 243
LK+ + +LQ QL + + R + + +E +EL +++ A
Sbjct: 602 ALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVET 661
Query: 244 -RARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESH 302
R E +A+VAE+ L+SE E++ + + +E Q+L E L V +
Sbjct: 662 ARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQL--QEQLQALKES--LKVTKGS 717
Query: 303 RKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEE 362
+ KR +++ + +K + + + K ++ L E L+ + ++
Sbjct: 718 LEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKE----LEEERAGRKGLEARLQQ 773
Query: 363 LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEY 422
L + Q E + L + + A A+SE E+A+ S +Y
Sbjct: 774 LGEAHQAETEVLRRELAEAMAAQH------TAESECEQLVKEVAAWRERYEDSQQEEAQY 827
Query: 423 KALFKEIFSCIK----KTKQEIDEQRTKYRSLSSHS 454
A+F+E +K K +QE+ E + K + SHS
Sbjct: 828 GAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHS 863
Score = 42.7 bits (99), Expect = 7e-04
Identities = 80/407 (19%), Positives = 148/407 (36%), Gaps = 44/407 (10%)
Query: 20 DHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVE-LLRQMNE 78
DH + + + G+ +R L S+++ + Q+ E E +K+++ L+ +E
Sbjct: 1201 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE 1260
Query: 79 QHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS 138
+ K+ E+L + E + + S A ++++ SL E E + ++L+ ++
Sbjct: 1261 KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE 1320
Query: 139 SGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHL 198
+ K QEK L L +H + + S E
Sbjct: 1321 RAEELGQELKAWQEKFFQKEQALSTLQ-------LEHTSTQALVS----------ELLPA 1363
Query: 199 KKTVTMLQA-QLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEM 257
K LQA Q + E++ R ELEQ A G RA L + E+ E+
Sbjct: 1364 KHLCQQLQAEQAAAEKRHR--------------EELEQSKQAAGGLRAELLRAQRELGEL 1409
Query: 258 RQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESH----RKPLKRSSSET 313
+ Q ++L + + E L + L E+ R L R E
Sbjct: 1410 IPLRQKVAEQERTAQQLRAEK--ASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEV 1467
Query: 314 ILSSLAGSDI-----VKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQ 368
L + V+ ET + + Q L + +Y KVK E ++ Q
Sbjct: 1468 ELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQ 1527
Query: 369 EEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSS 415
EE+ L+ + Q + V S+ +A + + V + + +
Sbjct: 1528 EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKA 1574
Score = 40.0 bits (92), Expect = 0.004
Identities = 91/464 (19%), Positives = 182/464 (39%), Gaps = 50/464 (10%)
Query: 8 EEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLT 67
E M+ E QDL+ + L + N +L +++ + ++ +QLQ+
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLRE-FASHLQQLQDA---- 340
Query: 68 KQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNID 127
L ++ E+H+K ++ +LE+ + D K ++K L + L+ ++
Sbjct: 341 -----LNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLS 395
Query: 128 HLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQ 187
LQ + K G + +++ A A +L + + ++ L +
Sbjct: 396 QLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETER--GQQEAKLLAE 453
Query: 188 PSPDEEENEHLKKTVTMLQAQLSLERQKRVTME---EEYGLVLKE------------NSE 232
EEE + L +T LQ+ +S Q + +E + +G L N+
Sbjct: 454 RGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Query: 233 LEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLE 292
++QQ + +A E +A++A Q LQ + G+ V + L K+ Q L E
Sbjct: 514 IQQQDQELAGLKQQAKEKQAQLA---QTLQQQEQASQGLRHQV-EQLSSSLKQKEQQLKE 569
Query: 293 --EMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVK----QRGISLL 346
E + H + L ++ E S +K E + + KA K Q+ + +
Sbjct: 570 VAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLE--ALEKEKAAKLEILQQQLQVA 627
Query: 347 HEV--DTQYSALKVKYE--ELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASG 402
+E Q S + + E EL +K +E Q V+T+R + A+ E
Sbjct: 628 NEARDSAQTSVTQAQREKAELSRKVEELQ-----ACVETARQEQHEAQAQVAELELQLRS 682
Query: 403 WELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTK 446
+ + E V+ + + + + +K TK ++E++ +
Sbjct: 683 EQQKATEKERVAQ--EKDQLQEQLQALKESLKVTKGSLEEEKRR 724
Score = 35.8 bits (81), Expect = 0.082
Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 31 AAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVT 90
AAE K +++ D+ +Q QEQL+ +E L K+ + LR E+ +Q +
Sbjct: 1606 AAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLK 1665
Query: 91 ARELEETNQKLVADSKASQQKILSLTETIECL---QTNIDHLQSQVEELK 137
+E E+T + L A ++ + ++ + + L Q D L+S+ + K
Sbjct: 1666 TKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAK 1715
Score = 34.7 bits (78), Expect = 0.18
Identities = 68/346 (19%), Positives = 133/346 (38%), Gaps = 45/346 (13%)
Query: 66 LTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTN 125
L ++V+ LR+ E+ E L E ++L + KA Q+K + + LQ
Sbjct: 1290 LREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLE 1349
Query: 126 IDHLQSQVEELKSSGQGRRSPGK--CDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITS 183
Q+ V EL P K C Q + + A + +L Q ++
Sbjct: 1350 HTSTQALVSEL--------LPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLR 1401
Query: 184 LQ---GQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSEL------- 233
Q G+ P ++ ++T L+A+ + ++ +++ +GL+ +EN L
Sbjct: 1402 AQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLG 1461
Query: 234 ------------EQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYV 281
E+ + A RA A E +AE+++ QS + + +
Sbjct: 1462 RQFLEVELDQAREKYVQELAAVRADA---ETRLAEVQREAQSTARELEVMTAKYEGAKVK 1518
Query: 282 PFKEPSQSLLEEMFLTVPESHRKPLKRSSS---ETILSSLAGSDIVKGHEETCIRRAKAV 338
+E + E LT + +R + E + LA SD ++ ++ KAV
Sbjct: 1519 VLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQ---QKLKAV 1575
Query: 339 KQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRA 384
+ +G E + L+ + EL + +++ + H +Q +A
Sbjct: 1576 QAQG----GESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKA 1617
Score = 34.7 bits (78), Expect = 0.18
Identities = 59/251 (23%), Positives = 109/251 (43%), Gaps = 55/251 (21%)
Query: 33 ELGKTLLDRNTELEDSVQQMYTTNQE-QLQEIEYLTKQVELLRQ---MNEQHAKV---YE 85
EL D T L + ++ +T +E ++ +Y +V++L + E+ K+ E
Sbjct: 1479 ELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVE 1538
Query: 86 QLDVTARE----LEETNQKLVADSKAS---QQKILSLT-------ETIECLQTNIDHLQS 131
QL+V RE +EE ++KL +AS QQK+ ++ + + LQ ++ LQ+
Sbjct: 1539 QLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQA 1598
Query: 132 QVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPD 191
Q+ + + + + K EK K YD ++ + E++ SL+
Sbjct: 1599 QLSQKEQAAEHY----KLQMEK-------AKTHYDAKKQ--QNQELQEQLRSLEQL---- 1641
Query: 192 EEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELE 251
++EN+ L+ L +L ++ GL KE + + L A+ LE
Sbjct: 1642 QKENKELRAEAERLGHEL-----------QQAGLKTKEAEQTCRHL------TAQVRSLE 1684
Query: 252 AEVAEMRQMLQ 262
A+VA Q L+
Sbjct: 1685 AQVAHADQQLR 1695
Score = 33.5 bits (75), Expect = 0.41
Identities = 58/263 (22%), Positives = 105/263 (39%), Gaps = 32/263 (12%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELE---DSVQQMYTTNQEQ 59
A+ V + + ++ E ++LQ ++ A + + ELE S QQ T +
Sbjct: 634 AQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERV 693
Query: 60 LQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETI 119
QE + L +Q++ L+ E L VT LEE ++ AD+ QQ+ +S E
Sbjct: 694 AQEKDQLQEQLQALK----------ESLKVTKGSLEEEKRR-AADALEEQQRCIS--ELK 740
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAE 179
++ ++ + + +EL+ GR+ A L++L + H V
Sbjct: 741 AETRSLVEQHKRERKELEEERAGRKG-----------LEARLQQLGE--AHQAETEVLRR 787
Query: 180 KITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRV---TMEEEYGLVLKENSELEQQ 236
++ E E E L K V + + +Q+ M +E + LKE E +Q
Sbjct: 788 ELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQ 847
Query: 237 LGATGAYRARALELEAEVAEMRQ 259
+ +E +E+ RQ
Sbjct: 848 ELQEAKEKVAGIESHSELQISRQ 870
Score = 32.3 bits (72), Expect = 0.91
Identities = 57/253 (22%), Positives = 95/253 (37%), Gaps = 37/253 (14%)
Query: 44 ELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQ---------------MNEQHAKVYEQLD 88
EL +++ +T E E L K+V R+ EQ + E+ +
Sbjct: 788 ELAEAMAAQHTAESE----CEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECE 843
Query: 89 VTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGK 148
+EL+E +K+ S+ +I + L N+ QV+E + Q
Sbjct: 844 KARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLS 903
Query: 149 CDQEKPAPSFACLKELYDL------RQHFVYDHVFAEKITSLQGQPS-PDEEENEHLKKT 201
QEK A + + L L +Q + E + QP +E++ T
Sbjct: 904 TLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCST 963
Query: 202 VTMLQA------QLSLERQK-RVTMEEEYGLVLKENSELEQQLGATGAYRARA---LELE 251
LQA Q+ E ++ R + E G +E + E+++ R RA L LE
Sbjct: 964 QAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALE 1023
Query: 252 -AEVAEMRQMLQS 263
A AE+ LQ+
Sbjct: 1024 KAARAELEMRLQN 1036
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 59.3 bits (142), Expect = 7e-09
Identities = 84/400 (21%), Positives = 167/400 (41%), Gaps = 52/400 (13%)
Query: 1 MLAENLVEEFEMKEDEPWYDHQDLQQDLQL-------AAELGKTLLDRNTELEDSVQQMY 53
+ AEN + E E + + + LQ+ LQ A EL L + ELE+ +
Sbjct: 862 LAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLE 921
Query: 54 TTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKIL 113
+E+ + ++L + ++M + ++ EQL+ E E QKL + ++ K+
Sbjct: 922 ARVEEEEERCQHLQAE---KKKMQQNIQELEEQLE----EEESARQKLQLEKVTTEAKLK 974
Query: 114 SLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVY 173
L E L+ L + ++L + ++E+ + S A LK ++
Sbjct: 975 KLEEEQIILEDQNCKLAKE-KKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHE------- 1026
Query: 174 DHVFAEKITSLQGQPSPDEEENEHLKKT--------------VTMLQAQLSLERQKRVTM 219
IT L+ + +E++ + L+KT + LQAQ++ + +
Sbjct: 1027 -----AMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKK 1081
Query: 220 EEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSL 279
EEE L + +E++ + ELE++++E+++ L+SE N EK D
Sbjct: 1082 EEELQAAL---ARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRD-- 1136
Query: 280 YVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGS--DIVKGHEETCIRRAKA 337
E ++L E+ T+ + + RS E ++ L + + K HE I+ +
Sbjct: 1137 ---LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ-IQEMRQ 1192
Query: 338 VKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHK 377
+ + L E Q +K E+ + + E+ L+++
Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANE 1232
Score = 43.1 bits (100), Expect = 5e-04
Identities = 58/289 (20%), Positives = 125/289 (43%), Gaps = 32/289 (11%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEI 63
E L +E + ED +LQ + A+ + L R+ + E+ +Q+ +E E+
Sbjct: 1542 EELEDELQATEDAKLRLEVNLQA---MKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
Query: 64 EYLTKQVEL------------------LRQMNEQHAKVYEQLDVTARELEETNQKLVADS 105
E KQ + + N+ + +QL ++++ ++L D+
Sbjct: 1599 EDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL-DDT 1657
Query: 106 KASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACL--KE 163
+AS+++IL+ + E +++ Q++E ++ + + + ++++ A A K
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 164 LYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKT---VTMLQAQLSLERQKRVTME 220
L + + A+ L+ + E N+ LKK + + L+LER E
Sbjct: 1718 ALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNE 1777
Query: 221 EEYGLVLKENSELE---QQLGAT--GAYRARALELEAEVAEMRQMLQSE 264
+ ++N EL+ Q++ T Y+A LEA++A++ + L +E
Sbjct: 1778 NARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNE 1826
Score = 40.4 bits (93), Expect = 0.003
Identities = 95/441 (21%), Positives = 184/441 (41%), Gaps = 63/441 (14%)
Query: 6 LVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEY 65
L +E ++ ED +L ++ + + L K L +++ + +++ ++Q QE+E
Sbjct: 990 LAKEKKLLEDRIAEFTTNLTEEEEKSKSLAK-LKNKHEAMITDLEERLRREEKQRQELEK 1048
Query: 66 LTKQVE-----LLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIE 120
+++E L Q+ E A++ E A++ EE L + + QK ++L + E
Sbjct: 1049 TRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRE 1108
Query: 121 CLQTNIDHLQSQVEELKSSG----QGRRSPG------KCDQEKPAPSFACLKELYDLRQH 170
L++ I LQ +E ++S + +R G K + E S A +EL R+
Sbjct: 1109 -LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQ 1167
Query: 171 FVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLS--LERQKRV---------TM 219
V ++ + +L+ + E + + +++ + +L+ LE+ KRV T+
Sbjct: 1168 EV--NILKK---TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 220 EEEYGLVLKENSELEQQLGATGAYR----ARALELEA----------EVAEMRQMLQSEH 265
E E G + E L Q G + R A+ EL+ E+A+ LQ E
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 266 PFVNGVEKLVPDSLYVPFKEPS--QSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDI 323
V G+ K+ S +S L++ + E +R+ L S+ + S
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 324 VKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSR 383
+ EE AK H ++ Q + L + ++ KK ++ L A + R
Sbjct: 1343 EQLEEE---EEAK----------HNLEKQIATLHAQVADMKKKMEDSVGCLE-TAEEVKR 1388
Query: 384 AAAKDLTGVNAQSEPVASGWE 404
KDL G++ + E + ++
Sbjct: 1389 KLQKDLEGLSQRHEEKVAAYD 1409
Score = 39.7 bits (91), Expect = 0.006
Identities = 98/450 (21%), Positives = 167/450 (37%), Gaps = 61/450 (13%)
Query: 5 NLVEEFEM--KEDEPWYDHQDLQQDLQLAAE-----LGKTLLDRNTELEDSVQQMYTTNQ 57
+L EE E E E D QQ+L+ E L KTL + E +Q+M Q
Sbjct: 1136 DLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEM---RQ 1192
Query: 58 EQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTE 117
+ Q +E L +Q+E +++ K + L+ EL + L+ S+ K +
Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEA 1252
Query: 118 TIECLQTNIDH-------LQSQVEELK---SSGQGRRSPGKCDQEKPAPSFACLKELYDL 167
++ LQ + L +V +L+ + G S K F+ L+
Sbjct: 1253 QLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQD 1312
Query: 168 RQHFVYDH-------------VFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQ 214
Q + + V EK S + Q +EE +L+K + L AQ++ ++
Sbjct: 1313 TQELLQEENRQKLSLSTKLKQVEDEK-NSFREQLEEEEEAKHNLEKQIATLHAQVADMKK 1371
Query: 215 KRV-------TMEEEYGLVLKENSEL----EQQLGATGAYRARALELEAEVAEMRQMLQS 263
K T EE + K+ L E+++ A L+ E+ ++ L
Sbjct: 1372 KMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDH 1431
Query: 264 EHPFVNGVEKLVP--DSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSS----ETILSS 317
+ +EK D L K S EE E+ K K S E +
Sbjct: 1432 QRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ 1491
Query: 318 LAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLS-- 375
A + + T + + K +HE++ AL+ + EE+ + +E +D L
Sbjct: 1492 KAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQAT 1551
Query: 376 -------HKAVQTSRAA-AKDLTGVNAQSE 397
+Q +A +DL G + QSE
Sbjct: 1552 EDAKLRLEVNLQAMKAQFERDLQGRDEQSE 1581
Score = 35.8 bits (81), Expect = 0.082
Identities = 49/243 (20%), Positives = 98/243 (40%), Gaps = 13/243 (5%)
Query: 33 ELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTAR 92
+L KT EL+D + + Q + K +LL + AK E+ D
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 93 ELEETNQKLVADSKASQQKI---LSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKC 149
E E K ++ ++A ++ + L + +T ++ L S +++ S +
Sbjct: 1470 EAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRA 1529
Query: 150 DQEKPAPSFACLKELYD---------LRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKK 200
+++ L+EL D LR + A+ LQG+ EE+ + L +
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1589
Query: 201 TVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARAL-ELEAEVAEMRQ 259
V ++A+L ER++R + + +LE + + R A+ +L A+M+
Sbjct: 1590 QVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKD 1649
Query: 260 MLQ 262
++
Sbjct: 1650 CMR 1652
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 55.5 bits (132), Expect = 1e-07
Identities = 76/361 (21%), Positives = 148/361 (40%), Gaps = 57/361 (15%)
Query: 57 QEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARE-----LEETNQKLVA---DSKAS 108
QE++ E+E + E + Q EQ ++ TA E L+E N+++ A D +A
Sbjct: 2405 QERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEAC 2464
Query: 109 QQKILSLTETIECLQ-------TNIDHLQSQVEELKSSGQG---RRSPGKCDQEKPAPSF 158
+ K +L+ +ECL+ +D ++ L+SS G GK EK
Sbjct: 2465 KAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEI 2524
Query: 159 ACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVT 218
+ LK ++ V K++ ++G+ +E+N L+ L+ ++ + + K +
Sbjct: 2525 SRLKNQIQDQEQLV------SKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNAS 2578
Query: 219 MEEEYGLVLKENSELEQQLGAT-----------GAYRARALELEAEVAEMRQMLQSEHPF 267
+++ ++ LE +L T A+ EL+ E+ EM Q
Sbjct: 2579 LQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEE 2638
Query: 268 VNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGH 327
++G + + L Q LLEE+ + + L+ S + L + + K
Sbjct: 2639 LSGEKNRLAGEL--------QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEK-- 2688
Query: 328 EETCIRRAKAVKQRGISLLHEVDTQYSAL--------KVKYEELLKKCQEEQDSLSHKAV 379
E +R A Q LHE + ++ AL +V+ + +K +++ LS + +
Sbjct: 2689 -EGKVREEIAEYQ---LRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKL 2744
Query: 380 Q 380
+
Sbjct: 2745 E 2745
Score = 51.6 bits (122), Expect = 1e-06
Identities = 87/369 (23%), Positives = 160/369 (43%), Gaps = 43/369 (11%)
Query: 41 RNTELEDSVQQMYTTNQEQLQEIE-YLTKQVELLRQMNEQHAKVYEQLDVTARELEE--- 96
+N EL + + ++ Q +E++ + K EL Q+ + ++ E+ V + +E
Sbjct: 286 QNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVR 345
Query: 97 -TNQKLVADSK--ASQQKILSLTETIECLQTNID----HLQSQVEELKSSGQ-----GRR 144
T Q A +K A +QK+ LTE + C + N + L+ +++E + Q +R
Sbjct: 346 TTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQR 405
Query: 145 SPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPD-EEENEHLKKTVT 203
S DQE +EL + +K+TS++ Q + EE + L +
Sbjct: 406 SFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQ 465
Query: 204 MLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARAL-ELEAEVAEMRQMLQ 262
QA E + R +MEE + KEN+ L+ +AR + LEAE+ ++Q L
Sbjct: 466 AFQASQIKENELRRSMEE----MKKENNLLKSH----SEQKAREVCHLEAELKNIKQCLN 517
Query: 263 SEHPFV------NGVEKLVPDSLYVPFKEPSQSL-LEEMFLTVPESHRKPLKRSSSETIL 315
F N ++ + L + SL LE++ L V + + +R S+ +L
Sbjct: 518 QSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEK---QRDCSQDLL 574
Query: 316 S------SLAGSDIVKGHEET-CIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQ 368
+ K +E+ + A +K++ L E T +S K + E+LL + +
Sbjct: 575 KKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQME 634
Query: 369 EEQDSLSHK 377
E+++L K
Sbjct: 635 SEKENLQSK 643
Score = 42.7 bits (99), Expect = 7e-04
Identities = 77/360 (21%), Positives = 146/360 (40%), Gaps = 40/360 (11%)
Query: 44 ELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVA 103
EL + T +QE +Q LT++ L+Q H + +LD +L Q+L
Sbjct: 399 ELSRQQRSFQTLDQECIQMKARLTQE---LQQAKNMHNVLQAELD----KLTSVKQQLEN 451
Query: 104 DSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLK- 162
+ + +QK+ + + Q + L+ +EE+K +S E+ A L+
Sbjct: 452 NLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKS----HSEQKAREVCHLEA 507
Query: 163 ELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEE 222
EL +++Q FAE+ ++ + + E L++ + + L+LE+ K +
Sbjct: 508 ELKNIKQCLNQSQNFAEE---MKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVAD-- 562
Query: 223 YGLVLKENSELEQQLGATGAYRARAL--ELEAEVAEMRQMLQSEHPFVNGVEKLVPD-SL 279
L++ + Q L + L +L E + +L + E+L + +L
Sbjct: 563 ----LEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTL 618
Query: 280 YVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVK 339
+ +K ++ LL +M ES ++ L+ S L + + +K HE R +
Sbjct: 619 FSCWKSENEKLLTQM-----ESEKENLQ--SKINHLETCLKTQQIKSHEYNERVRTLEMD 671
Query: 340 QRGISL----LHEV----DTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTG 391
+ +S+ LH V + K+ Y EL +K E D K ++ LTG
Sbjct: 672 RENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKA-EFSDQKHQKEIENMCLKTSQLTG 730
Score = 42.7 bits (99), Expect = 7e-04
Identities = 57/226 (25%), Positives = 110/226 (48%), Gaps = 20/226 (8%)
Query: 23 DLQQDL-----QLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTK-QVELLRQM 76
+LQ++L +LA EL + LL+ +D ++++ N E + ++ + K QVE ++
Sbjct: 2634 ELQEELSGEKNRLAGEL-QLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKV 2692
Query: 77 NEQHAKVYEQLDVTARE----LEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQ 132
E+ A+ +L ++ L +TN++ + + ++K+ S E + + ID L+S
Sbjct: 2693 REEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSS 2752
Query: 133 VEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDE 192
EEL +S ++ + +E LK + L++ + K+ L E
Sbjct: 2753 KEELNNS---LKATTQILEELKKTKMDNLKYVNQLKKE---NERAQGKMKLLIKSCKQLE 2806
Query: 193 EENEHLKKTVTMLQAQLSLERQKRVT-MEEEYGLVLKENSELEQQL 237
EE E L+K ++ LQA + E+QK T M+ + + E EL++ L
Sbjct: 2807 EEKEILQKELSQLQA--AQEKQKTGTVMDTKVDELTTEIKELKETL 2850
Score = 41.6 bits (96), Expect = 0.001
Identities = 82/386 (21%), Positives = 163/386 (42%), Gaps = 58/386 (15%)
Query: 40 DRNTELEDSVQQMYTTNQE-QLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETN 98
DR+ ++E + +M + + LQE++ +TK +E ++ K+ +L +L E
Sbjct: 1792 DRDRKVESLLNEMKELDSKLHLQEVQLMTK-IEACIELE----KIVGELKKENSDLSEKL 1846
Query: 99 QKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSF 158
+ D Q++L ET E L ++++ + + + G +E+
Sbjct: 1847 EYFSCD----HQELLQRVETSEGLNSDLE-MHADKSSREDIGDNVAKVNDSWKERFLDVE 1901
Query: 159 ACLKELYDLRQHFVYDHVFAEK-ITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRV 217
L + + ++ ++ E + +Q + E++NE+ +K + L+ +LS+ +R
Sbjct: 1902 NELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERN 1961
Query: 218 TMEEEYGLVLKENSELEQQLGATGAYRARALE------------LEAEVAEMRQMLQSEH 265
+ E + K+ + L+ QL + + LE EAEV E ++LQ+
Sbjct: 1962 QLRGELDTMSKKTTALD-QLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT-- 2018
Query: 266 PFVNGVEKLVPDSLYVPFKEPSQSLLEE---MFLTVPE--------SHRKPLKRSSSETI 314
+ V +L+ D ++ +E QSL ++ + LT E + K L SE++
Sbjct: 2019 -LSSDVSELLKDKTHL--QEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESL 2075
Query: 315 LSSLAGSDIVKGHEETCIRRAKAVK-QRGISL------LHEVDTQYSALKVKYE------ 361
+ L+ SD K + + A K + + L +H++ L+V+ E
Sbjct: 2076 QARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQ 2135
Query: 362 ----ELLKKCQEEQDSLSHKAVQTSR 383
E LK+ + E DSL K R
Sbjct: 2136 LHIAEKLKERERENDSLKDKVENLER 2161
Score = 33.1 bits (74), Expect = 0.53
Identities = 44/193 (22%), Positives = 77/193 (39%), Gaps = 23/193 (11%)
Query: 60 LQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADS------KASQQKIL 113
LQ+I+ L Q++ L++ +Q QLD L++ QK+ + K Q+++
Sbjct: 17 LQKIQELEGQLDKLKKEKQQRQF---QLDSLEAALQKQKQKVENEKTEGTNLKRENQRLM 73
Query: 114 SLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSF-ACLKELYDLRQHFV 172
+ E++E + I H E + +G+ + GK EK C EL +Q
Sbjct: 74 EICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQ--- 130
Query: 173 YDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSE 232
A + + P N K T L K ++E+Y ++E
Sbjct: 131 -----AAQSADVSLNPC-----NTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKR 180
Query: 233 LEQQLGATGAYRA 245
LE ++ A A +A
Sbjct: 181 LEAEVKALQAKKA 193
Score = 32.3 bits (72), Expect = 0.91
Identities = 62/292 (21%), Positives = 103/292 (35%), Gaps = 75/292 (25%)
Query: 2 LAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQ-- 59
L EN E E ++ +HQ+ L A E + L+ ++ +++ T NQ
Sbjct: 1063 LCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSK 1122
Query: 60 -------------LQEIEYLTKQVELLRQMNEQHAKVYE--------------------- 85
+E + K+V L Q NEQ KV +
Sbjct: 1123 SEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERE 1182
Query: 86 ----------QLDVTARE--LEETNQKLVADSKASQQKILSLTET---IECLQTNIDHLQ 130
Q+D+ +E L+ N +LV + K L L E+ ECLQ + ++
Sbjct: 1183 SERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIR 1242
Query: 131 SQVEELK-SSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPS 189
+E Q + G D E A EK S + S
Sbjct: 1243 GDLETSNLQDMQSQEISGLKDCEIDA----------------------EEKYISGPHELS 1280
Query: 190 PDEEENEHLKKTVTMLQAQLS-LERQKRVTMEEEYGLVLKENSELEQQLGAT 240
+ +N HL+ ++ +L+ LE+ + E+Y LV + N + + AT
Sbjct: 1281 TSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITAT 1332
Score = 30.4 bits (67), Expect = 3.5
Identities = 34/150 (22%), Positives = 62/150 (41%), Gaps = 25/150 (16%)
Query: 21 HQDLQQDLQLAAELGKTLLDR----------NTELEDSVQQMYTTNQEQLQEIEYLTKQV 70
+ L+ Q+ EL KT +D N + ++ + + ++ +E E L K++
Sbjct: 2757 NNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKEL 2816
Query: 71 ELLRQMNEQH-------AKVYEQLDVTARELEETNQKLVADSKASQQKILS-------LT 116
L+ E+ KV ++L +EL+ET ++ ++ K S L
Sbjct: 2817 SQLQAAQEKQKTGTVMDTKV-DELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLE 2875
Query: 117 ETIECLQTNIDHLQSQVEELKSSGQGRRSP 146
+ E L+T + HL SQ + S G P
Sbjct: 2876 KAKEMLETQVAHLCSQQSKQDSRGSPLLGP 2905
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 54.7 bits (130), Expect = 2e-07
Identities = 80/363 (22%), Positives = 156/363 (42%), Gaps = 56/363 (15%)
Query: 44 ELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVA 103
ELE + + TN+ QE+EYLT+ V+ L + ++ +L + EL+ ++ +
Sbjct: 119 ELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKY 178
Query: 104 DSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKE 163
K +Q+ L L T L+++ +EL + G+ + + E
Sbjct: 179 REKRLEQEKELLHSQNTWLNT---ELKTKTDELLALGREKGN-----------------E 218
Query: 164 LYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEY 223
+ +L+ + E+++ L+ Q + + NEHL+K V L +L ++++ +MEE++
Sbjct: 219 ILELKCNLENK---KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF 275
Query: 224 GLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFV---NGVEKLVPDSLY 280
++EL + + Y++ A + EA+ E+ + ++ H + K + D L
Sbjct: 276 ------HNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLL 329
Query: 281 VPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEE------TCIRR 334
E S+ +E+ L K L+ ++ +LS+ + EE T
Sbjct: 330 E--VEQSKDQMEKEMLEKIGRLEKELENAND--LLSATKRKGAILSEEELAAMSPTAAAV 385
Query: 335 AKAVKQRGISLLH----EVDTQYSALKVKYE---------ELLKKCQEEQDSLSHKAVQT 381
AK VK G+ L V+TQ L K E E++K+ + + L + +
Sbjct: 386 AKIVKP-GMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEY 444
Query: 382 SRA 384
RA
Sbjct: 445 ERA 447
Score = 44.7 bits (104), Expect = 2e-04
Identities = 65/270 (24%), Positives = 120/270 (44%), Gaps = 45/270 (16%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTEL--------EDSVQQMYT 54
AENL +E EM + Q Q++ LA + G+ LL N + E +Q +
Sbjct: 781 AENLKKEKEMLKLSEVRLSQ--QRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLS 838
Query: 55 TNQEQLQ-EIEYLTKQVELLRQMNEQHAKVYEQLDV----TARELE-ETNQKLVADSKAS 108
+ E+L+ EI +L K++E ++ ++H + LDV T R+L+ ETN L +
Sbjct: 839 SQIEKLEHEISHLKKKLE--NEVEQRHT-LTRNLDVQLLDTKRQLDTETNLHL-----NT 890
Query: 109 QQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLR 168
++ + + + I L+ ++ +++ QV S G+ P + S LR
Sbjct: 891 KELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVS--------QLR 942
Query: 169 QHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLK 228
Q E++ L+ + E + VT L+ L+ E+Q + + + LK
Sbjct: 943 QT-------EEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLK 995
Query: 229 ENSELEQQLGATGAYRARALELEAEVAEMR 258
E++E + QL + +E+E E E++
Sbjct: 996 ESAEFQTQL------EKKLMEVEKEKQELQ 1019
Score = 42.4 bits (98), Expect = 9e-04
Identities = 67/331 (20%), Positives = 134/331 (40%), Gaps = 47/331 (14%)
Query: 45 LEDSVQQMYTTNQEQL-QEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVA 103
LE+ V++ NQ + Q+ + T++ L E H K +QL L+ + A
Sbjct: 1328 LEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNA 1387
Query: 104 DSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKE 163
+Q I SL E + ++T + +Q ++ D ++ + +K+
Sbjct: 1388 SLTNNQNLIQSLKEDLNKVRTEKETIQKDLD-----------AKIIDIQEKVKTITQVKK 1436
Query: 164 LYDLRQHFVYDHVFA--EKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEE 221
+ R Y+ + A +K+ Q S D +E + + L+ L+ K ++E
Sbjct: 1437 I-GRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLES 1495
Query: 222 EYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYV 281
+ + K SE E + + + ++L++E++ +RQ LQ
Sbjct: 1496 QVENLQKTLSEKETE---ARNLQEQTVQLQSELSRLRQDLQD------------------ 1534
Query: 282 PFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAG--SDIVKGHEETCIRRAKAVK 339
+ + L + E RK + + S+ ++ LAG + K +EE R +
Sbjct: 1535 --RTTQEEQLRQQITEKEEKTRKAIVAAKSK--IAHLAGVKDQLTKENEELKQRNGALDQ 1590
Query: 340 QRGISLLHEVDTQYSALKVKYEELLKKCQEE 370
Q+ E+D + +ALK +YE + + + E
Sbjct: 1591 QK-----DELDVRITALKSQYEGRISRLERE 1616
Score = 38.5 bits (88), Expect = 0.013
Identities = 98/513 (19%), Positives = 202/513 (39%), Gaps = 79/513 (15%)
Query: 2 LAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLD---RNTELEDSVQQMYTTNQE 58
L E+L +E ++ E+ L++ + +L K L++ EL+D ++ + ++
Sbjct: 972 LEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQ 1031
Query: 59 QLQEIEYLTKQV-----ELLRQ-----MNEQHAK--VYEQLDVTARELEETNQKLVADS- 105
QL E++ V E L++ NEQ A+ EQ + + ++L+ +
Sbjct: 1032 QLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAA 1091
Query: 106 -----KASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFAC 160
+A+++++ + + L+ +SQ+ E K+S + R K + K C
Sbjct: 1092 DVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSK------C 1145
Query: 161 LKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLS----LERQKR 216
+ DL + + + ++I L + +E V++ + S LE +
Sbjct: 1146 VCRCEDLEKQ---NRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRF 1202
Query: 217 VTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVP 276
+ E+E E +++E YR R LE E+ E++ L +E V K +
Sbjct: 1203 IRREKEIAETRFEVAQVESL-----RYRQRVELLERELQELQDSLNAEREKVQVTAKTMA 1257
Query: 277 DSLYVPFKEPSQSLLEEMFLTVPESHRK--------------------PLKRSSSETILS 316
+ K + +++ E + E + PL+ +++E LS
Sbjct: 1258 QHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAE--LS 1315
Query: 317 SLAGS-DIVKGHEETCIRRAKAVKQRGISLLHEVDT-QYSALKVKYEELLKKCQEEQDSL 374
+G K E ++R KA Q +S + DT +Y L + E K+ Q+ + +
Sbjct: 1316 EKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEI 1375
Query: 375 SHKAVQTSRAAA-------------KDLTGVNAQSEPVASGWELASVN-PEPVSSPTTPP 420
+ +R+ A +DL V + E + + ++ E V + T
Sbjct: 1376 GRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVK 1435
Query: 421 EYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSH 453
+ +K + +K + ++ E T +S H
Sbjct: 1436 KIGRRYKTQYEELKAQQDKVME--TSAQSSGDH 1466
Score = 37.7 bits (86), Expect = 0.022
Identities = 111/553 (20%), Positives = 203/553 (36%), Gaps = 123/553 (22%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQE 62
A+ V +K ++ + Q LQ+D A + L N +E V+ + + L E
Sbjct: 447 AQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLME 506
Query: 63 I------------EYLTKQVELLRQMNEQHAKVYEQLD----------VTARELEETNQK 100
+ E + + ++ QH Y ++ V REL ET ++
Sbjct: 507 LEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETRER 566
Query: 101 LVADSKASQQKILSLTETIECLQTNIDHLQ------------------------------ 130
+ + + KI L +E T ++ L+
Sbjct: 567 --EEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGV 624
Query: 131 ------SQVEELKSSGQGRRSPGKCDQEKPAP-----------SFACLKELYDLRQHFVY 173
S ++++ + +R PAP + A LK+L ++ +++
Sbjct: 625 AIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKK 684
Query: 174 DHVFAEKI------------TSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEE 221
+ EKI T L+ Q + + + K MLQ + R + +T
Sbjct: 685 EKAENEKIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYR-REITSLH 743
Query: 222 EYGLVLKENSELEQQLGATGAYRARALELEAEVAEMR-QMLQSEHPFVNGVEKLVPDSLY 280
E L ++ ++Q+ T R + VAE+R + L+ E + E
Sbjct: 744 ERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSE-------- 795
Query: 281 VPFKEPSQSLLEE-----MFLTVPESHRKPLKRSSSET--ILSSLAG------SDIVKGH 327
V + +SLL E + LT ++ + L+RS +ET LSS S + K
Sbjct: 796 VRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKL 855
Query: 328 EETCIRRAKAVKQRGISLL---HEVDTQYSALKVKYEELLKKCQEE----QDSLSHKAVQ 380
E +R + + LL ++DT+ + L + +ELLK Q+E + LS+ VQ
Sbjct: 856 ENEVEQRHTLTRNLDVQLLDTKRQLDTE-TNLHLNTKELLKNAQKEIATLKQHLSNMEVQ 914
Query: 381 -TSRAAAKDLTGVNAQSEPVASGWELASVNPEPV--------SSPTTPPEYKALFKEIFS 431
S+++ + G + E V E V +S + +Y+A+ +
Sbjct: 915 VASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE 974
Query: 432 CIKKTKQEIDEQR 444
+ K KQ +E R
Sbjct: 975 SLNKEKQVTEEVR 987
Score = 36.6 bits (83), Expect = 0.048
Identities = 53/208 (25%), Positives = 80/208 (38%), Gaps = 30/208 (14%)
Query: 20 DHQDLQQDLQLAAELGKTLLDRNTE---LEDSVQQMYTTNQEQLQEIEYLTKQ------- 69
DHQ+ +Q EL +TL T+ LE V+ + T E+ E L +Q
Sbjct: 1465 DHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSE 1524
Query: 70 VELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHL 129
+ LRQ + EQL E EE +K + A++ KI L D L
Sbjct: 1525 LSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIV---AAKSKIAHLAGV-------KDQL 1574
Query: 130 QSQVEELKSSGQGRRSPGKCDQEKPA--PSFACLKELYDLRQHFVYDHVFAEKITSLQGQ 187
+ EELK G DQ+K LK Y+ R + + + L+ +
Sbjct: 1575 TKENEELKQRN------GALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQR 1628
Query: 188 PSPDEEENE--HLKKTVTMLQAQLSLER 213
P E N+ ++ +T+ S ER
Sbjct: 1629 DEPQEPSNKVPEQQRQITLKTTPASGER 1656
Score = 30.8 bits (68), Expect = 2.6
Identities = 68/338 (20%), Positives = 125/338 (36%), Gaps = 60/338 (17%)
Query: 58 EQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTE 117
E ++E+E ++ R+ E+ K L V + + Q+L D+ + ++ L
Sbjct: 425 EIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLER 484
Query: 118 TIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVF 177
++ + L Q+ L L EL + R +HV
Sbjct: 485 DNRRMEIQVKDLSQQIRVL------------------------LMELEEARG----NHVI 516
Query: 178 AEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL 237
++ S S E ++HL + +L + Q+ + E G E E E+Q
Sbjct: 517 RDEEVSSADISSSSEVISQHLVSYRNI--EELQQQNQRLLVALRELG----ETREREEQE 570
Query: 238 GATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLT 297
+ L+LE+ + E+ Q+ +S + V+ +V ++ + LL +
Sbjct: 571 TTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQ------RDMYRILLSQTTGV 624
Query: 298 VPESHRKPL---------KRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHE 348
H L KR S+ +S+ A +++ E I A+KQ L E
Sbjct: 625 AIPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTE--AIEAKAALKQ-----LQE 677
Query: 349 VDTQYSALKVKYE----ELLKKCQEEQDSLSHKAVQTS 382
+ Y K + E E L+K QE+ L + + S
Sbjct: 678 IFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKIS 715
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/267 (22%), Positives = 120/267 (44%), Gaps = 44/267 (16%)
Query: 17 PWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQM--YTTNQEQLQE--IEYLTKQVEL 72
P + + L+ ++ E +TL + E + ++++ + EQ+QE + +Q +L
Sbjct: 79 PSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL 138
Query: 73 LRQMNEQHAKVYEQLDVTARELEE-----------TNQKLVADSKAS--QQKILSLTETI 119
R++ E + E L+ R +EE T K +A+ +A QQ++ +L E +
Sbjct: 139 QRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 198
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAE 179
+ L T+++ L++++EE S G Y L+Q + +
Sbjct: 199 DELTTDLEILKAEIEEKGSDGAA--------------------SSYQLKQLEEQNARLKD 238
Query: 180 KITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-G 238
+ ++ S +++E+ L+K + +L + RQ+R ++EE EL++Q+
Sbjct: 239 ALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDA 298
Query: 239 ATGAYRA------RALELEAEVAEMRQ 259
A GA R L LE +V E+R+
Sbjct: 299 ALGAEEMVEMLTDRNLNLEEKVRELRE 325
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/173 (24%), Positives = 77/173 (44%), Gaps = 20/173 (11%)
Query: 11 EMKEDEPWYDHQDLQQDLQLAAE-LGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTK- 68
E+ + E D Q D L AE + + L DRN LE+ V+++ +E + ++E + +
Sbjct: 281 ELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVREL----RETVGDLEAMNEM 336
Query: 69 QVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDH 128
EL E ++ EQLD+ + E +++ +A+Q+ + +TI+ + H
Sbjct: 337 NDELQENARETELELREQLDMAGARVREAQKRV----EAAQETVADYQQTIKKYRQLTAH 392
Query: 129 LQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKI 181
LQ EL + + Q++P P E +D + F A+ I
Sbjct: 393 LQDVNRELTNQQEASVE----RQQQPPP------ETFDFKIKFAETKAHAKAI 435
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 14/125 (11%)
Query: 24 LQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAK- 82
L+ ++ A LG L DR T +++ +++ E+L E ++ LL + + AK
Sbjct: 797 LRAEITDAEGLGLKLEDRETVIKE-LKKSLKIKGEELSEANV---RLSLLEKKLDSAAKD 852
Query: 83 VYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS--SG 140
E+++ LEET L ++K ET++ LQ +ID L+++ ELK +
Sbjct: 853 ADERIEKVQTRLEETQALL-------RKKEKEFEETMDALQADIDQLEAEKAELKQRLNS 905
Query: 141 QGRRS 145
Q +R+
Sbjct: 906 QSKRT 910
Score = 29.6 bits (65), Expect = 5.9
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAP----SFACLKELYDLRQHFVYDH 175
ECL+ + + L S + +L ++ Q + KP P + A E+ D +
Sbjct: 753 ECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLE 812
Query: 176 VFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSL------ERQKRVT--MEEEYGLVL 227
I L+ EE +++L+ +L ER ++V +EE L+
Sbjct: 813 DRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLR 872
Query: 228 KENSELEQQLGATGAYRARALELEAEVAEMRQMLQSE 264
K+ E E+ + A +A +LEAE AE++Q L S+
Sbjct: 873 KKEKEFEETMDAL---QADIDQLEAEKAELKQRLNSQ 906
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/267 (22%), Positives = 120/267 (44%), Gaps = 44/267 (16%)
Query: 17 PWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQM--YTTNQEQLQE--IEYLTKQVEL 72
P + + L+ ++ E +TL + E + ++++ + EQ+QE + +Q +L
Sbjct: 193 PSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL 252
Query: 73 LRQMNEQHAKVYEQLDVTARELEE-----------TNQKLVADSKAS--QQKILSLTETI 119
R++ E + E L+ R +EE T K +A+ +A QQ++ +L E +
Sbjct: 253 QRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 312
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAE 179
+ L T+++ L++++EE S G Y L+Q + +
Sbjct: 313 DELTTDLEILKAEIEEKGSDGAA--------------------SSYQLKQLEEQNARLKD 352
Query: 180 KITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-G 238
+ ++ S +++E+ L+K + +L + RQ+R ++EE EL++Q+
Sbjct: 353 ALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDA 412
Query: 239 ATGAYRA------RALELEAEVAEMRQ 259
A GA R L LE +V E+R+
Sbjct: 413 ALGAEEMVEMLTDRNLNLEEKVRELRE 439
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/173 (24%), Positives = 77/173 (44%), Gaps = 20/173 (11%)
Query: 11 EMKEDEPWYDHQDLQQDLQLAAE-LGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTK- 68
E+ + E D Q D L AE + + L DRN LE+ V+++ +E + ++E + +
Sbjct: 395 ELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVREL----RETVGDLEAMNEM 450
Query: 69 QVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDH 128
EL E ++ EQLD+ + E +++ +A+Q+ + +TI+ + H
Sbjct: 451 NDELQENARETELELREQLDMAGARVREAQKRV----EAAQETVADYQQTIKKYRQLTAH 506
Query: 129 LQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKI 181
LQ EL + + Q++P P E +D + F A+ I
Sbjct: 507 LQDVNRELTNQQEASVE----RQQQPPP------ETFDFKIKFAETKAHAKAI 549
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 14/125 (11%)
Query: 24 LQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAK- 82
L+ ++ A LG L DR T +++ +++ E+L E ++ LL + + AK
Sbjct: 911 LRAEITDAEGLGLKLEDRETVIKE-LKKSLKIKGEELSEANV---RLSLLEKKLDSAAKD 966
Query: 83 VYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS--SG 140
E+++ LEET L ++K ET++ LQ +ID L+++ ELK +
Sbjct: 967 ADERIEKVQTRLEETQALL-------RKKEKEFEETMDALQADIDQLEAEKAELKQRLNS 1019
Query: 141 QGRRS 145
Q +R+
Sbjct: 1020 QSKRT 1024
Score = 29.6 bits (65), Expect = 5.9
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAP----SFACLKELYDLRQHFVYDH 175
ECL+ + + L S + +L ++ Q + KP P + A E+ D +
Sbjct: 867 ECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLE 926
Query: 176 VFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSL------ERQKRVT--MEEEYGLVL 227
I L+ EE +++L+ +L ER ++V +EE L+
Sbjct: 927 DRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLR 986
Query: 228 KENSELEQQLGATGAYRARALELEAEVAEMRQMLQSE 264
K+ E E+ + A +A +LEAE AE++Q L S+
Sbjct: 987 KKEKEFEETMDAL---QADIDQLEAEKAELKQRLNSQ 1020
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/267 (22%), Positives = 120/267 (44%), Gaps = 44/267 (16%)
Query: 17 PWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQM--YTTNQEQLQE--IEYLTKQVEL 72
P + + L+ ++ E +TL + E + ++++ + EQ+QE + +Q +L
Sbjct: 79 PSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL 138
Query: 73 LRQMNEQHAKVYEQLDVTARELEE-----------TNQKLVADSKAS--QQKILSLTETI 119
R++ E + E L+ R +EE T K +A+ +A QQ++ +L E +
Sbjct: 139 QRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 198
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAE 179
+ L T+++ L++++EE S G Y L+Q + +
Sbjct: 199 DELTTDLEILKAEIEEKGSDGAA--------------------SSYQLKQLEEQNARLKD 238
Query: 180 KITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-G 238
+ ++ S +++E+ L+K + +L + RQ+R ++EE EL++Q+
Sbjct: 239 ALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDA 298
Query: 239 ATGAYRA------RALELEAEVAEMRQ 259
A GA R L LE +V E+R+
Sbjct: 299 ALGAEEMVEMLTDRNLNLEEKVRELRE 325
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/173 (24%), Positives = 77/173 (44%), Gaps = 20/173 (11%)
Query: 11 EMKEDEPWYDHQDLQQDLQLAAE-LGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTK- 68
E+ + E D Q D L AE + + L DRN LE+ V+++ +E + ++E + +
Sbjct: 281 ELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVREL----RETVGDLEAMNEM 336
Query: 69 QVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDH 128
EL E ++ EQLD+ + E +++ +A+Q+ + +TI+ + H
Sbjct: 337 NDELQENARETELELREQLDMAGARVREAQKRV----EAAQETVADYQQTIKKYRQLTAH 392
Query: 129 LQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKI 181
LQ EL + + Q++P P E +D + F A+ I
Sbjct: 393 LQDVNRELTNQQEASVE----RQQQPPP------ETFDFKIKFAETKAHAKAI 435
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 14/125 (11%)
Query: 24 LQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAK- 82
L+ ++ A LG L DR T +++ +++ E+L E ++ LL + + AK
Sbjct: 797 LRAEITDAEGLGLKLEDRETVIKE-LKKSLKIKGEELSEANV---RLSLLEKKLDSAAKD 852
Query: 83 VYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS--SG 140
E+++ LEET L ++K ET++ LQ +ID L+++ ELK +
Sbjct: 853 ADERIEKVQTRLEETQALL-------RKKEKEFEETMDALQADIDQLEAEKAELKQRLNS 905
Query: 141 QGRRS 145
Q +R+
Sbjct: 906 QSKRT 910
Score = 29.6 bits (65), Expect = 5.9
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAP----SFACLKELYDLRQHFVYDH 175
ECL+ + + L S + +L ++ Q + KP P + A E+ D +
Sbjct: 753 ECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLE 812
Query: 176 VFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSL------ERQKRVT--MEEEYGLVL 227
I L+ EE +++L+ +L ER ++V +EE L+
Sbjct: 813 DRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLR 872
Query: 228 KENSELEQQLGATGAYRARALELEAEVAEMRQMLQSE 264
K+ E E+ + A +A +LEAE AE++Q L S+
Sbjct: 873 KKEKEFEETMDAL---QADIDQLEAEKAELKQRLNSQ 906
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 53.5 bits (127), Expect = 4e-07
Identities = 60/267 (22%), Positives = 120/267 (44%), Gaps = 44/267 (16%)
Query: 17 PWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQM--YTTNQEQLQE--IEYLTKQVEL 72
P + + L+ ++ E +TL + E + ++++ + EQ+QE + +Q +L
Sbjct: 213 PSKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADL 272
Query: 73 LRQMNEQHAKVYEQLDVTARELEE-----------TNQKLVADSKAS--QQKILSLTETI 119
R++ E + E L+ R +EE T K +A+ +A QQ++ +L E +
Sbjct: 273 QRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 332
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAE 179
+ L T+++ L++++EE S G Y L+Q + +
Sbjct: 333 DELTTDLEILKAEIEEKGSDGAA--------------------SSYQLKQLEEQNARLKD 372
Query: 180 KITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-G 238
+ ++ S +++E+ L+K + +L + RQ+R ++EE EL++Q+
Sbjct: 373 ALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDA 432
Query: 239 ATGAYRA------RALELEAEVAEMRQ 259
A GA R L LE +V E+R+
Sbjct: 433 ALGAEEMVEMLTDRNLNLEEKVRELRE 459
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/173 (24%), Positives = 77/173 (44%), Gaps = 20/173 (11%)
Query: 11 EMKEDEPWYDHQDLQQDLQLAAE-LGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTK- 68
E+ + E D Q D L AE + + L DRN LE+ V+++ +E + ++E + +
Sbjct: 415 ELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVREL----RETVGDLEAMNEM 470
Query: 69 QVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDH 128
EL E ++ EQLD+ + E +++ +A+Q+ + +TI+ + H
Sbjct: 471 NDELQENARETELELREQLDMAGARVREAQKRV----EAAQETVADYQQTIKKYRQLTAH 526
Query: 129 LQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKI 181
LQ EL + + Q++P P E +D + F A+ I
Sbjct: 527 LQDVNRELTNQQEASVE----RQQQPPP------ETFDFKIKFAETKAHAKAI 569
Score = 35.4 bits (80), Expect = 0.11
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 14/125 (11%)
Query: 24 LQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAK- 82
L+ ++ A LG L DR T +++ +++ E+L E ++ LL + + AK
Sbjct: 931 LRAEITDAEGLGLKLEDRETVIKE-LKKSLKIKGEELSEANV---RLSLLEKKLDSAAKD 986
Query: 83 VYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS--SG 140
E+++ LEET L ++K ET++ LQ +ID L+++ ELK +
Sbjct: 987 ADERIEKVQTRLEETQALL-------RKKEKEFEETMDALQADIDQLEAEKAELKQRLNS 1039
Query: 141 QGRRS 145
Q +R+
Sbjct: 1040 QSKRT 1044
Score = 29.6 bits (65), Expect = 5.9
Identities = 39/157 (24%), Positives = 68/157 (43%), Gaps = 15/157 (9%)
Query: 120 ECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAP----SFACLKELYDLRQHFVYDH 175
ECL+ + + L S + +L ++ Q + KP P + A E+ D +
Sbjct: 887 ECLRQSCNILISTMNKLATAMQEGEYDAERPPSKPPPVELRAAALRAEITDAEGLGLKLE 946
Query: 176 VFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSL------ERQKRVT--MEEEYGLVL 227
I L+ EE +++L+ +L ER ++V +EE L+
Sbjct: 947 DRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQALLR 1006
Query: 228 KENSELEQQLGATGAYRARALELEAEVAEMRQMLQSE 264
K+ E E+ + A +A +LEAE AE++Q L S+
Sbjct: 1007 KKEKEFEETMDAL---QADIDQLEAEKAELKQRLNSQ 1040
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 53.5 bits (127), Expect = 4e-07
Identities = 81/415 (19%), Positives = 179/415 (43%), Gaps = 56/415 (13%)
Query: 25 QQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVY 84
+++LQ E + ++ T++E +++M +Q+ L+E L +Q++ ++ + ++
Sbjct: 851 EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMR 910
Query: 85 EQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRR 144
+L +ELEE L + + +++ L + +Q +I L+ Q++E + + Q +
Sbjct: 911 ARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 145 SPGKCDQEKPAPSFACLKELYDLRQHFVYD-HVFAEKITSLQGQPSPDEEENEHLKK--- 200
+ K + L D F+ + + ++I Q + +EE+ ++L K
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 201 ----TVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGA-------------- 242
++ L+ +L E + R +E+ + E ++L+ Q+ A
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 243 --------------YRARAL----ELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFK 284
++ AL EL+A++AE+++ +SE N EK D
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD-----LS 1145
Query: 285 EPSQSLLEEMFLTVPESHRKPLKRSSSETILSSL--AGSDIVKGHEETCIRRAKAVKQRG 342
E ++L E+ T+ + + R+ E ++ L A + K HE + + ++QR
Sbjct: 1146 EELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHE----AQIQDMRQRH 1201
Query: 343 ISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSE 397
+ L E+ Q K +++ L+K ++ ++ + + K L V A+SE
Sbjct: 1202 ATALEELSEQLEQAK-RFKANLEKNKQGLETDNKELA----CEVKVLQQVKAESE 1251
Score = 52.0 bits (123), Expect = 1e-06
Identities = 96/427 (22%), Positives = 172/427 (40%), Gaps = 50/427 (11%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQE 62
AE + K+ E DL+ ++ E + L + +++ +Q + +EQL E
Sbjct: 906 AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDL----EEQLDE 961
Query: 63 IEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETI--- 119
E ++++L + E K E+ + LE+ N K + + K + +I + +
Sbjct: 962 EEGARQKLQLEKVTAEAKIKKMEEEILL---LEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 120 ECLQTNIDHLQSQVEELKSSGQGR-RSPGKCDQEKPAPSFACLKELYDLRQHFV-----Y 173
E N+ ++++ E + S + R + K QE E DL+
Sbjct: 1019 EEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQI 1078
Query: 174 DHV---FAEKITSLQGQPSPDEEENEHLK---KTVTMLQAQLS---------------LE 212
D + A+K LQG + ++E H K V LQAQ++ E
Sbjct: 1079 DELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAE 1138
Query: 213 RQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVE 272
+QKR EE L +ELE L T A + + E EVAE+++ L+ E
Sbjct: 1139 KQKRDLSEELEAL----KTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQI 1194
Query: 273 KLVPDSLYVPFKEPSQSLLE-EMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETC 331
+ + +E S+ L + + F E +++ L+ + E + + VK E
Sbjct: 1195 QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKE-LACEVKVLQQVKAESEHK 1253
Query: 332 IRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLS---HKAVQTSRAAAKD 388
++ A Q LH ++ L+V+ E K Q E D++S +A + AKD
Sbjct: 1254 RKKLDAQVQE----LHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKD 1309
Query: 389 LTGVNAQ 395
+ +Q
Sbjct: 1310 AASLESQ 1316
Score = 45.8 bits (107), Expect = 8e-05
Identities = 61/267 (22%), Positives = 110/267 (41%), Gaps = 27/267 (10%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLR-QMNEQH 80
QD Q+ LQ L R +LE+ + +E+ + + L KQV L+ Q+ +
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 81 AKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSG 140
KV + L T LEE +KL+ D++A Q++ + L+ + LQ ++++L
Sbjct: 1378 KKVDDDLG-TIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDL 1436
Query: 141 QGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAE--------KITSLQGQPSPDE 192
+R ++K L E + + + AE K SL
Sbjct: 1437 DHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEAL 1496
Query: 193 EENEHLKKTVTMLQAQL---------------SLERQKRVTMEEEYGLVLKENSELEQQL 237
E E ++ L+A + LE+ KR +E++ + + ELE +L
Sbjct: 1497 EAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKR-ALEQQVEEMRTQLEELEDEL 1555
Query: 238 GATGAYRAR-ALELEAEVAEMRQMLQS 263
AT + R + ++A A+ + LQ+
Sbjct: 1556 QATEDAKLRLEVNMQAMKAQFERDLQT 1582
Score = 41.6 bits (96), Expect = 0.001
Identities = 85/379 (22%), Positives = 152/379 (40%), Gaps = 76/379 (20%)
Query: 22 QDLQQD-LQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLR-QMNEQ 79
Q L+ D +LA E+ K L E E +++ Q+QE+ + + LR ++ E+
Sbjct: 1227 QGLETDNKELACEV-KVLQQVKAESEHKRKKL----DAQVQELHAKVSEGDRLRVELAEK 1281
Query: 80 HAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNID---HLQSQVEEL 136
+K+ +LD + LEE +K + +K + L +T E LQ +L S++ +L
Sbjct: 1282 ASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQL 1341
Query: 137 KSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENE 196
+ E+ SLQ Q +EE +
Sbjct: 1342 E-----------------------------------------EEKNSLQEQQEEEEEARK 1360
Query: 197 HLKKTVTMLQAQLSLERQKRV--------TMEEEYGLVLKENSELEQQLG----ATGAYR 244
+L+K V LQ+QL+ + +K+V ++EE +LK+ L Q+L A
Sbjct: 1361 NLEKQVLALQSQLA-DTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE 1419
Query: 245 ARALELEAEVAEMRQMLQSEHPFVNGVEKLVP--DSLYVPFKEPSQSLLEEMFLTVPESH 302
L+ E+ ++ L + + +EK D L K S EE E+
Sbjct: 1420 KTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAR 1479
Query: 303 RKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISL-------LHEVDTQYSA 355
K K S + +L + K E ++ +A + +S +HE++ A
Sbjct: 1480 EKETKALS---LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRA 1536
Query: 356 LKVKYEELLKKCQEEQDSL 374
L+ + EE+ + +E +D L
Sbjct: 1537 LEQQVEEMRTQLEELEDEL 1555
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 53.5 bits (127), Expect = 4e-07
Identities = 92/442 (20%), Positives = 164/442 (37%), Gaps = 54/442 (12%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
++L +++ E L L+++ QQ Q + ++ L K L Q +
Sbjct: 980 KNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLE 1039
Query: 82 KVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQ 141
EQ +LE +KL D K SQ+ I+ L + ++ + + ++ +L++
Sbjct: 1040 GSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQA--- 1096
Query: 142 GRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKT 201
K D E+ V+ F +KI LQ + EEE E
Sbjct: 1097 ------KIDDEQ------------------VHSLQFQKKIKELQARIEELEEEIE----A 1128
Query: 202 VTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQML 261
L+A++ +R EE + LE+ GAT A + EAE +MR+ L
Sbjct: 1129 EHTLRAKIEKQRSDLARELEEI------SERLEEASGATSAQIEMNKKREAEFQKMRRDL 1182
Query: 262 QS---EHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSL 318
+ +H + E +L + E + LK + +
Sbjct: 1183 EEATLQHEATAATLRKKQADSVAELGEQIDNL--QRVKQKLEKEKSELKMEIDDMASNIE 1240
Query: 319 AGSDIVKGHEETC------IRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQD 372
A S E TC KA ++ L+H+++ Q + L+ + EL + EE++
Sbjct: 1241 ALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRV-EEKE 1299
Query: 373 SLSHKAVQTSRAAAKDLTGVNAQSEPV-----ASGWELASVNPEPVSSPTTPPEYKALFK 427
SL + ++ +A + L + Q E A L S + E +
Sbjct: 1300 SLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKA 1359
Query: 428 EIFSCIKKTKQEIDEQRTKYRS 449
E+ + K E+ + RTKY +
Sbjct: 1360 ELQRALSKANSEVAQWRTKYET 1381
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/275 (18%), Positives = 113/275 (41%), Gaps = 26/275 (9%)
Query: 7 VEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYL 66
+++ ++ D+ ++DL++ L + LL+ E++ +++Q T + QE+
Sbjct: 1654 LKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDA 1713
Query: 67 TKQVELLRQMNEQHAKVYEQLDV--------------TARELEETNQKLVADSKASQQKI 112
+ +V+LL N ++L+ +R EE +K + D+ +++
Sbjct: 1714 SDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEEL 1773
Query: 113 LSLTETIECLQTNIDHLQSQVEELK----SSGQGRRSPGKCDQEKPAPSFACLKELYDLR 168
+T L+ +L+ V++L+ + Q GK +K L+ D+
Sbjct: 1774 KKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVE 1833
Query: 169 QHFVYD-----HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEY 223
Q + H + K+ + Q D + L+ V LQA++ +++ EE+
Sbjct: 1834 QKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQA 1893
Query: 224 GLVLKENSELEQQLGATGAYRARALELEAEVAEMR 258
L ++ +L RA E++V ++R
Sbjct: 1894 NTQLSRCRRVQHELEEAA---ERADIAESQVNKLR 1925
Score = 38.9 bits (89), Expect = 0.010
Identities = 87/424 (20%), Positives = 166/424 (39%), Gaps = 46/424 (10%)
Query: 40 DRNTELEDSVQQMYTTNQEQLQ-EIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETN 98
+ NTE +S +++LQ E+E L + +E K D E ++
Sbjct: 1405 EENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKL 1464
Query: 99 QKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSF 158
+ A+ +A+Q++ SL+ + ++ + + Q+E L+ + + E+ A +
Sbjct: 1465 DESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETG 1524
Query: 159 ACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSL---ERQK 215
L+E ++ + ++ + LQ E EH + + +Q +LS E +
Sbjct: 1525 KNLQEAEKTKK------LVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDR 1578
Query: 216 RVTMEEEYGLVLKENSE-----LEQQLGATGAYRARALEL----EAEVAEM--------R 258
+V ++E LK NS+ L+ L A R AL L E ++ EM R
Sbjct: 1579 KVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNR 1638
Query: 259 QMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSL 318
QM +++ +L L++ S L+E V R L E + +L
Sbjct: 1639 QMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIV--ERRNGLLLEELEEMKVAL 1696
Query: 319 AGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKA 378
++ + E + A + LLH +T K K E + +CQ E ++ +
Sbjct: 1697 EQTERTRRLSEQELLDASD----RVQLLHSQNTSLINTKKKLEADIAQCQAEVEN----S 1748
Query: 379 VQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQ 438
+Q SR NA+ + + + A + E T + + K + +K +
Sbjct: 1749 IQESR---------NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Query: 439 EIDE 442
+DE
Sbjct: 1800 RLDE 1803
Score = 38.1 bits (87), Expect = 0.017
Identities = 48/247 (19%), Positives = 112/247 (45%), Gaps = 26/247 (10%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
+ +++ + AEL + L N+E+ + T ++ +E+E K++ Q E++
Sbjct: 1349 EQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENT 1408
Query: 82 KVYEQLDVTARELEETNQKL---VADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS 138
E + LE+T Q+L V D ++ + T++ Q N D + ++ ++
Sbjct: 1409 ---ETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLD 1465
Query: 139 SGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHL 198
Q + + S + EL+ +R Y+ V +++ +L+ EN++L
Sbjct: 1466 ESQAELEAAQKE------SRSLSTELFKMRN--AYEEV-VDQLETLR-------RENKNL 1509
Query: 199 KKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL----GATGAYRARALELEAEV 254
++ ++ L Q++ + E+ LV +E S+L+ L G+ ++ L ++ E+
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLEL 1569
Query: 255 AEMRQML 261
++++ L
Sbjct: 1570 SQVKSEL 1576
Score = 34.3 bits (77), Expect = 0.24
Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 8/127 (6%)
Query: 20 DHQDLQQDLQ--------LAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVE 71
+ Q +++DL+ AA L K D EL + + + Q+ +E L +++
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233
Query: 72 LLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQS 131
+ E +K ++ T R +E+ ++ A + Q I L LQT L
Sbjct: 1234 DMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSH 1293
Query: 132 QVEELKS 138
+VEE +S
Sbjct: 1294 RVEEKES 1300
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 52.4 bits (124), Expect = 8e-07
Identities = 58/268 (21%), Positives = 115/268 (42%), Gaps = 40/268 (14%)
Query: 29 QLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLD 88
+L EL + L ++N ++ED Q++ Q+Q E +T ++Q E++ K+ + L
Sbjct: 1167 RLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLV 1226
Query: 89 VTARELEETNQ----------KLVADSKASQQKI----LSLTETIECLQTNIDHLQSQVE 134
T +EL ++ Q L + +ASQQ++ + L E +HL++ E
Sbjct: 1227 KTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAE 1286
Query: 135 ELK----------SSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSL 184
+ + ++ Q K +Q F E Y +R H V + ++
Sbjct: 1287 QHQRTLSAYQQRVTALQEECRAAKAEQATVTSEF----ESYKVRVHNVLKQQKNKSMS-- 1340
Query: 185 QGQPSPDEEENEHLKKTVTML-------QAQLSLERQKRVTMEEEYGLVLKENSELEQQL 237
Q + ++E EHL+ + L Q L + + T++ E+ +L+ ++++ Q+
Sbjct: 1341 QAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQE- 1399
Query: 238 GATGAYRARALELEAEVAEMRQMLQSEH 265
T + A E + M++SEH
Sbjct: 1400 --TVSKEAELREKLCSIQSENMMMKSEH 1425
Score = 46.6 bits (109), Expect = 5e-05
Identities = 87/412 (21%), Positives = 171/412 (41%), Gaps = 63/412 (15%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQE 62
A + +EFE + + D +LQQ L+ A LL+ L+ +++ + QE + E
Sbjct: 498 AGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKL-LSQQELVPE 556
Query: 63 IEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECL 122
+E K L++ N + Q D +ELE KI SLTE +
Sbjct: 557 LENTIKN---LQEKNGVYLLSLSQRDTMLKELE--------------GKINSLTEEKDDF 599
Query: 123 QTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKIT 182
I+ L++ EE+ + + KC++E+ L+ + Q Y+ +K+
Sbjct: 600 ---INKLKNSHEEMDNFHK------KCEREER----LILELGKKVEQTIQYNSELEQKVN 646
Query: 183 SLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGA 242
L G +E + + + L Q+ + + + + E + +EN++L +
Sbjct: 647 ELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSE------ 700
Query: 243 YRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLE---------- 292
+ + +LE +++ ++ EH + +EK + L V ++ LLE
Sbjct: 701 KKQLSRDLEVFLSQKEDVILKEH--ITQLEKKL--QLMVEEQDNLNKLLENEQVQKLFVK 756
Query: 293 -EMFLTVPESHRKPLKRSSSETILSSL--AGSDIVKGHEETCIRRAKAVKQRGISLLHEV 349
+++ + E + + S + +++ L G + K +EE C QR +L E+
Sbjct: 757 TQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKC----NLAFQRDEKVL-EL 811
Query: 350 DTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVAS 401
+ + L+ EE + +C EE SL Q K+L + ++ E + S
Sbjct: 812 EKEIKCLQ---EESVVQC-EELKSLLRDYEQEKVLLRKELEEIQSEKEALQS 859
Score = 43.9 bits (102), Expect = 3e-04
Identities = 95/445 (21%), Positives = 181/445 (40%), Gaps = 77/445 (17%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEI 63
++ + + + +E H+ +++ +L ELGK V+Q N E Q++
Sbjct: 597 DDFINKLKNSHEEMDNFHKKCEREERLILELGK-----------KVEQTIQYNSELEQKV 645
Query: 64 EYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
LT +E + +Q+ + E+L V + L E + L A+ K+ ++ L+ + L
Sbjct: 646 NELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLS 705
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCD-QEKPAPSFACLKELYDLRQHFVYDHVFAEKIT 182
+++ SQ E++ + K + + L E +++ FV ++ +
Sbjct: 706 RDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYG-FLK 764
Query: 183 SLQGQPSPDEEENEHLKKTVTMLQA-------------QLSLERQKRVTMEEEYGLVLKE 229
+ + S D EE K V +LQA L+ +R ++V E+ L+E
Sbjct: 765 EMGSEVSEDSEE----KDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQE 820
Query: 230 NS--ELEQQLGATGAYRARALELEAEVAEM---RQMLQS---EHPFVNGVEKLVPDSLYV 281
S + E+ Y + L E+ E+ ++ LQS E N +L +L +
Sbjct: 821 ESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLI 880
Query: 282 PFKEPSQSL--------LEEMFLTVPES-----HRKPLKRSSSETIL--SSLAGSDIVKG 326
+E SQ+ E+ F+ E+ +K L+ +E IL SLA S VK
Sbjct: 881 QVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKN 940
Query: 327 HEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAA 386
+ ++ L+ K E L K+C+E+++ + +K + A
Sbjct: 941 DPLSSVKE---------------------LEEKIENLEKECKEKEEKI-NKIKLVAVKAK 978
Query: 387 KDLTGVNAQSEPVASGWELASVNPE 411
K+L +++ V EL S+ E
Sbjct: 979 KELDSSRKETQTVKE--ELESLRSE 1001
Score = 35.8 bits (81), Expect = 0.082
Identities = 95/483 (19%), Positives = 190/483 (39%), Gaps = 64/483 (13%)
Query: 11 EMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQV 70
E+ ED + +D+ LQ +G++L N E + Q E +EI+ L ++
Sbjct: 769 EVSEDS---EEKDVVNVLQA---VGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEES 822
Query: 71 ELLRQMNEQHAKVYEQLDVTAR-ELEETNQKLVADSKASQQKILSLTETIECLQTNIDHL 129
+ + + + YEQ V R ELEE + ++ +A Q +L + E + +L
Sbjct: 823 VVQCEELKSLLRDYEQEKVLLRKELEE----IQSEKEALQSDLLEMKNANEKTRLENQNL 878
Query: 130 QSQVEELK---SSGQGRRSPGKC---DQEKPAPSFACLKELYDLRQHFVY--DHV----- 176
QVEE+ S + KC + E P KEL D R + D +
Sbjct: 879 LIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLE-QKELRDRRAELILLKDSLAKSPS 937
Query: 177 -----------FAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGL 225
EKI +L+ + EE+ +K + +L R++ T++EE
Sbjct: 938 VKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELES 997
Query: 226 VLKENSELEQQ----LGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYV 281
+ E +L + +Y+ LE E + ++ + + F + +E L
Sbjct: 998 LRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNS 1057
Query: 282 PFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQR 341
+ + + E L E+ + K + + A + + K E +++ + +K+
Sbjct: 1058 TLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEH 1117
Query: 342 G--ISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTS-------------RAAA 386
++ L E+ Q K ++ L+K +E + + A QT+ +
Sbjct: 1118 ATTVNELEELQVQLQ----KEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELN 1173
Query: 387 KDLTGVNAQSEPVASGWEL-----ASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEID 441
+ LT N + E + ++ ++ E S ++ +Y+ +I + KTK+E+
Sbjct: 1174 QKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELA 1233
Query: 442 EQR 444
+ +
Sbjct: 1234 DSK 1236
Score = 34.3 bits (77), Expect = 0.24
Identities = 42/158 (26%), Positives = 67/158 (42%), Gaps = 11/158 (6%)
Query: 10 FEMKEDEPWYDHQDLQQDLQLAAELGKT---LLDRNTELEDSVQQMYTTNQEQLQEIEYL 66
F++K + QQ L+ E T LLD +T + + M TT+ E +
Sbjct: 1473 FQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTY 1532
Query: 67 TKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNI 126
T+ +E L +N K+ L EE QKL + +K++ L ET +
Sbjct: 1533 TQSLEQL--LNSPETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRET----EATN 1586
Query: 127 DHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKEL 164
L Q++ LKS + RR ++EK A + LK +
Sbjct: 1587 AILMEQIKLLKS--EIRRLERNQEREKSAANLEYLKNV 1622
Score = 33.1 bits (74), Expect = 0.53
Identities = 50/234 (21%), Positives = 89/234 (38%), Gaps = 18/234 (7%)
Query: 8 EEFEMKEDEPWYDHQDLQQDLQL-AAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYL 66
E EM D+ QD Q +LQ+ +EL + +T LE + + T ++ + E L
Sbjct: 1352 EHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKL 1411
Query: 67 TKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNI 126
M +H + QL L + + V + +K T+E LQ +
Sbjct: 1412 CSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRK------TVETLQQQL 1465
Query: 127 DHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQG 186
+++Q+ +LK+ R P S LK L + R++ + +T +G
Sbjct: 1466 SKMEAQLFQLKNEPTTR---------SPVSSQQSLKNLRE-RRNTDLPLLDMHTVTREEG 1515
Query: 187 QPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT 240
+ + + E + T Q+ L +E EL Q+L +T
Sbjct: 1516 E-GMETTDTESVSSASTYTQSLEQLLNSPETKLEPPLWHAEFTKEELVQKLSST 1568
Score = 32.0 bits (71), Expect = 1.2
Identities = 81/401 (20%), Positives = 167/401 (41%), Gaps = 68/401 (16%)
Query: 29 QLAAELGKTLLDRNTELEDSVQQMYTTNQE-------QLQEIEYLTKQVELLR-QMNEQH 80
Q L K + E+EDSV +M ++E ++EIE L ++ +R + +E
Sbjct: 90 QQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDK 149
Query: 81 AKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNID----HLQSQVEEL 136
A + +QL+ E +++L + S+ + L E IE ++ + +LQ Q++
Sbjct: 150 ANLQKQLEEAMNTQLELSEQLKFQNN-SEDNVKKLQEEIEKIRPGFEEQILYLQKQLD-- 206
Query: 137 KSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHF-----VYDHVFAEKITSLQGQPSPD 191
++ + + + + A S K + L++ ++ E + ++
Sbjct: 207 ATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEH 266
Query: 192 EEE----NEHLKKTVTMLQA---------QLSLERQKRVTMEEEY-----GLVLKENSEL 233
E E NE + V +A + LE ++ T ++L+EN+ +
Sbjct: 267 EAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFV 326
Query: 234 EQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVE-KLVPDSLYVP-----FKEPS 287
EQ + + L+ E+ +L+ E ++N ++ KL D+ ++ +E
Sbjct: 327 EQVVNEKVKHLEDTLK---ELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDL 383
Query: 288 QSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSD-----IVKGHEETCIRRAKAVKQRG 342
+ + E+ L E + E + S LAG + V+ H ++ K Q+
Sbjct: 384 EFKINELLLAKEE------QGCVIEKLKSELAGLNKQFCYTVEQHNRE-VQSLKEQHQKE 436
Query: 343 ISLLHEV---DTQYSALKVKYE--ELLKKC----QEEQDSL 374
IS L+E D++ L + +E L ++C QE+Q+++
Sbjct: 437 ISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAI 477
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 52.4 bits (124), Expect = 8e-07
Identities = 83/395 (21%), Positives = 160/395 (40%), Gaps = 50/395 (12%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQL-------AAELGKTLLDRNTELEDSVQQMYTT 55
AEN ++E E K + + LQ+ LQ A E+ L + ELE+ + +M
Sbjct: 871 AENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM--- 927
Query: 56 NQEQLQEIEYLTKQVELLR-QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILS 114
+ +L+E E +Q++ R +M +Q + EQL+ E E QKL + ++ KI
Sbjct: 928 -EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAARQKLQLEKVTAEAKIKK 982
Query: 115 LTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD 174
L + I + + L S+ +L + ++E+ A + LK ++
Sbjct: 983 LEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-------- 1033
Query: 175 HVFAEKITSLQGQPSPDEEENEHLKK--------------TVTMLQAQLSLERQKRVTME 220
I+ L+ + +E+ + L+K + LQAQ++ + + E
Sbjct: 1034 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 221 EEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLY 280
EE L + L+ ++ + ELE ++++++ L SE N EK D
Sbjct: 1090 EELQAAL---ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD--L 1144
Query: 281 VPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQ 340
E ++ LE+ + KR T+L A + + HE ++ +
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK-ALDEETRSHEAQ-VQEMRQKHA 1202
Query: 341 RGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLS 375
+ + L E Q+ K ++ + ++E L+
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Score = 50.1 bits (118), Expect = 4e-06
Identities = 95/420 (22%), Positives = 162/420 (38%), Gaps = 57/420 (13%)
Query: 5 NLVEEFEM--KEDEPWYDHQDLQQDLQLAAELGKTLLDR--NTELEDSVQQMYTTNQEQL 60
+L EE E E E D QQ+L+ E T+L + + E Q+ Q+
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 61 QEIEYLTKQVELLRQ-----------MNEQHAKVYEQLDVTAR---ELEETNQKLVADSK 106
Q +E LT+Q+E ++ + +++A + +L V + E+E +KL A +
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 107 ASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYD 166
Q K L + LQ++VE + +G + GK K A A L
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESV--TGMLNEAEGKAI--KLAKDVASLSSQLQ 1318
Query: 167 LRQHFVYDHV------------FAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQ 214
Q + + E+ SLQ Q + E ++L++ ++ L QLS ++
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 215 KR-------VTMEEEYGLVLKENSELEQQ----LGATGAYRARALELEAEVAEMRQMLQS 263
K +EE KE L QQ A L+ E+ ++ L +
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 264 EHPFVNGVEKLVP--DSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGS 321
+ V+ +EK D L K S +E E+ K K S + +L +
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS---LARALEEA 1495
Query: 322 DIVKGHEETCIRRAKAVKQRGISL-------LHEVDTQYSALKVKYEELLKKCQEEQDSL 374
K E + KA + +S +HE++ AL+ + EE+ + +E +D L
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 45.8 bits (107), Expect = 8e-05
Identities = 90/441 (20%), Positives = 181/441 (41%), Gaps = 66/441 (14%)
Query: 23 DLQQDLQLAAELGKTL--LDRNTELEDSVQQMYTTNQE--QLQEIEYLTKQVELLRQMNE 78
DL QL + L K D+ E ++ Y ++ + + E TK + L R + E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL-E 1493
Query: 79 QHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS 138
+ + E+L+ T + L+ + LV+ + + L ++ L+T ++ +++Q+EEL
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL-- 1551
Query: 139 SGQGRRSPGKCDQEKPAPSFACLK---ELYDLRQHFVYDHVFAEKITSLQGQPSPDEEEN 195
+ E A A L+ + L+ F D LQ + +EE+
Sbjct: 1552 -----------EDELQATEDAKLRLEVNMQALKGQFERD---------LQARDEQNEEKR 1591
Query: 196 EHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVA 255
L++ + + +L ER++R + + +LE Q A A + R E +
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGR----EEAIK 1645
Query: 256 EMRQMLQSEHPFVNGVE--KLVPDSLYVPFKE---PSQSLLEEMF-----LTVPESHRKP 305
++R++ F +E + D ++ KE ++SL ++ L E RK
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
Query: 306 L---KRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEE 362
K +E + SSL+G + ++ + RR +A R L E++ + ++ +
Sbjct: 1706 ADLEKEELAEELASSLSGRNALQDEK----RRLEA---RIAQLEEELEEEQGNMEAMSDR 1758
Query: 363 LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEY 422
+ K Q+ + + A + S A + +A+ + EL S E +
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNE----SARQQLERQNKELRSKLHEMEGA------V 1808
Query: 423 KALFKEIFSCIKKTKQEIDEQ 443
K+ FK + ++ +++EQ
Sbjct: 1809 KSKFKSTIAALEAKIAQLEEQ 1829
Score = 45.4 bits (106), Expect = 1e-04
Identities = 102/457 (22%), Positives = 194/457 (42%), Gaps = 70/457 (15%)
Query: 8 EEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLT 67
EE + KEDE Q ++ Q A K L ++++L + + QEQLQ L
Sbjct: 852 EEMQAKEDEL----QKTKERQQKAENELKELEQKHSQLTEEKNLL----QEQLQAETELY 903
Query: 68 KQVELLR----QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ E +R ++ ++ +++ E E+ Q+L A+ K Q++L L E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE------ 957
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD--------- 174
Q+EE +++ Q K EK + A +K+L D + V D
Sbjct: 958 --------QLEEEEAARQ------KLQLEK-VTAEAKIKKLED--EILVMDDQNNKLSKE 1000
Query: 175 -HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSEL 233
+ E+I+ L + +EE+ ++L K ++ +S E + R+ EE+ +E +L
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS-ELEVRLKKEEK---SRQELEKL 1056
Query: 234 EQQL-GATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLE 292
+++L G + + +L+A++AE++ L + + + D + K + +
Sbjct: 1057 KRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE--IAQKNNALKKIR 1114
Query: 293 EMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQ 352
E+ E H L+ E + S A + + + +A+K L TQ
Sbjct: 1115 EL-----EGHISDLQ----EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1165
Query: 353 YSALKVKYEE---LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVN 409
L+ K E+ +LKK +E ++ SH+A Q K V +E + ++ A N
Sbjct: 1166 -QELRAKREQEVTVLKKALDE-ETRSHEA-QVQEMRQKHAQAVEELTEQLEQ-FKRAKAN 1221
Query: 410 PEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTK 446
+ + T E L E+ + + KQE++ ++ K
Sbjct: 1222 LDK-NKQTLEKENADLAGEL-RVLGQAKQEVEHKKKK 1256
Score = 36.6 bits (83), Expect = 0.048
Identities = 48/248 (19%), Positives = 100/248 (40%), Gaps = 25/248 (10%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
+D ++ LAA K L +LE +E ++++ L Q++ ++ E
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 82 KVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQ 141
+++ TA+E E+ + L AD Q+ + + + Q +++ + EEL SS
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEK-EELAEELASSLS 1722
Query: 142 GRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKT 201
GR + Q++ A + +L E++ QG + +
Sbjct: 1723 GRNAL----QDEKRRLEARIAQL-------------EEELEEEQGNMEAMSDRVRKATQQ 1765
Query: 202 VTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-----GATGAYRARALELEAEVAE 256
L +L+ ER E + ++N EL +L +++ LEA++A+
Sbjct: 1766 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825
Query: 257 MRQMLQSE 264
+ + ++ E
Sbjct: 1826 LEEQVEQE 1833
Score = 34.7 bits (78), Expect = 0.18
Identities = 31/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)
Query: 39 LDRNTELEDSVQQMYTTNQEQL-QEIEYLTKQVELLRQMNEQHAKVYE-------QLDVT 90
L+ E E +Q T + +Q ++++ + QVE R+M EQ+ + E QL
Sbjct: 1826 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
Query: 91 ARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSG--QGRRSPGK 148
E EE +Q++ A+ + Q+++ TE+ E + ++ L+S++ + RRS G+
Sbjct: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGR 1945
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 52.4 bits (124), Expect = 8e-07
Identities = 83/395 (21%), Positives = 160/395 (40%), Gaps = 50/395 (12%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQL-------AAELGKTLLDRNTELEDSVQQMYTT 55
AEN ++E E K + + LQ+ LQ A E+ L + ELE+ + +M
Sbjct: 878 AENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM--- 934
Query: 56 NQEQLQEIEYLTKQVELLR-QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILS 114
+ +L+E E +Q++ R +M +Q + EQL+ E E QKL + ++ KI
Sbjct: 935 -EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAARQKLQLEKVTAEAKIKK 989
Query: 115 LTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD 174
L + I + + L S+ +L + ++E+ A + LK ++
Sbjct: 990 LEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-------- 1040
Query: 175 HVFAEKITSLQGQPSPDEEENEHLKK--------------TVTMLQAQLSLERQKRVTME 220
I+ L+ + +E+ + L+K + LQAQ++ + + E
Sbjct: 1041 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 221 EEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLY 280
EE L + L+ ++ + ELE ++++++ L SE N EK D
Sbjct: 1097 EELQAAL---ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD--L 1151
Query: 281 VPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQ 340
E ++ LE+ + KR T+L A + + HE ++ +
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK-ALDEETRSHEAQ-VQEMRQKHA 1209
Query: 341 RGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLS 375
+ + L E Q+ K ++ + ++E L+
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1244
Score = 50.1 bits (118), Expect = 4e-06
Identities = 95/420 (22%), Positives = 162/420 (38%), Gaps = 57/420 (13%)
Query: 5 NLVEEFEM--KEDEPWYDHQDLQQDLQLAAELGKTLLDR--NTELEDSVQQMYTTNQEQL 60
+L EE E E E D QQ+L+ E T+L + + E Q+ Q+
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 61 QEIEYLTKQVELLRQ-----------MNEQHAKVYEQLDVTAR---ELEETNQKLVADSK 106
Q +E LT+Q+E ++ + +++A + +L V + E+E +KL A +
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 107 ASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYD 166
Q K L + LQ++VE + +G + GK K A A L
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESV--TGMLNEAEGKAI--KLAKDVASLSSQLQ 1325
Query: 167 LRQHFVYDHV------------FAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQ 214
Q + + E+ SLQ Q + E ++L++ ++ L QLS ++
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 215 KR-------VTMEEEYGLVLKENSELEQQ----LGATGAYRARALELEAEVAEMRQMLQS 263
K +EE KE L QQ A L+ E+ ++ L +
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 264 EHPFVNGVEKLVP--DSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGS 321
+ V+ +EK D L K S +E E+ K K S + +L +
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS---LARALEEA 1502
Query: 322 DIVKGHEETCIRRAKAVKQRGISL-------LHEVDTQYSALKVKYEELLKKCQEEQDSL 374
K E + KA + +S +HE++ AL+ + EE+ + +E +D L
Sbjct: 1503 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 45.8 bits (107), Expect = 8e-05
Identities = 90/441 (20%), Positives = 181/441 (41%), Gaps = 66/441 (14%)
Query: 23 DLQQDLQLAAELGKTL--LDRNTELEDSVQQMYTTNQE--QLQEIEYLTKQVELLRQMNE 78
DL QL + L K D+ E ++ Y ++ + + E TK + L R + E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL-E 1500
Query: 79 QHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS 138
+ + E+L+ T + L+ + LV+ + + L ++ L+T ++ +++Q+EEL
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL-- 1558
Query: 139 SGQGRRSPGKCDQEKPAPSFACLK---ELYDLRQHFVYDHVFAEKITSLQGQPSPDEEEN 195
+ E A A L+ + L+ F D LQ + +EE+
Sbjct: 1559 -----------EDELQATEDAKLRLEVNMQALKGQFERD---------LQARDEQNEEKR 1598
Query: 196 EHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVA 255
L++ + + +L ER++R + + +LE Q A A + R E +
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGR----EEAIK 1652
Query: 256 EMRQMLQSEHPFVNGVE--KLVPDSLYVPFKE---PSQSLLEEMF-----LTVPESHRKP 305
++R++ F +E + D ++ KE ++SL ++ L E RK
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712
Query: 306 L---KRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEE 362
K +E + SSL+G + ++ + RR +A R L E++ + ++ +
Sbjct: 1713 ADLEKEELAEELASSLSGRNALQDEK----RRLEA---RIAQLEEELEEEQGNMEAMSDR 1765
Query: 363 LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEY 422
+ K Q+ + + A + S A + +A+ + EL S E +
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNE----SARQQLERQNKELRSKLHEMEGA------V 1815
Query: 423 KALFKEIFSCIKKTKQEIDEQ 443
K+ FK + ++ +++EQ
Sbjct: 1816 KSKFKSTIAALEAKIAQLEEQ 1836
Score = 45.4 bits (106), Expect = 1e-04
Identities = 102/457 (22%), Positives = 194/457 (42%), Gaps = 70/457 (15%)
Query: 8 EEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLT 67
EE + KEDE Q ++ Q A K L ++++L + + QEQLQ L
Sbjct: 859 EEMQAKEDEL----QKTKERQQKAENELKELEQKHSQLTEEKNLL----QEQLQAETELY 910
Query: 68 KQVELLR----QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ E +R ++ ++ +++ E E+ Q+L A+ K Q++L L E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE------ 964
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD--------- 174
Q+EE +++ Q K EK + A +K+L D + V D
Sbjct: 965 --------QLEEEEAARQ------KLQLEK-VTAEAKIKKLED--EILVMDDQNNKLSKE 1007
Query: 175 -HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSEL 233
+ E+I+ L + +EE+ ++L K ++ +S E + R+ EE+ +E +L
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS-ELEVRLKKEEK---SRQELEKL 1063
Query: 234 EQQL-GATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLE 292
+++L G + + +L+A++AE++ L + + + D + K + +
Sbjct: 1064 KRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE--IAQKNNALKKIR 1121
Query: 293 EMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQ 352
E+ E H L+ E + S A + + + +A+K L TQ
Sbjct: 1122 EL-----EGHISDLQ----EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1172
Query: 353 YSALKVKYEE---LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVN 409
L+ K E+ +LKK +E ++ SH+A Q K V +E + ++ A N
Sbjct: 1173 -QELRAKREQEVTVLKKALDE-ETRSHEA-QVQEMRQKHAQAVEELTEQLEQ-FKRAKAN 1228
Query: 410 PEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTK 446
+ + T E L E+ + + KQE++ ++ K
Sbjct: 1229 LDK-NKQTLEKENADLAGEL-RVLGQAKQEVEHKKKK 1263
Score = 36.6 bits (83), Expect = 0.048
Identities = 48/248 (19%), Positives = 100/248 (40%), Gaps = 25/248 (10%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
+D ++ LAA K L +LE +E ++++ L Q++ ++ E
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 82 KVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQ 141
+++ TA+E E+ + L AD Q+ + + + Q +++ + EEL SS
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEK-EELAEELASSLS 1729
Query: 142 GRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKT 201
GR + Q++ A + +L E++ QG + +
Sbjct: 1730 GRNAL----QDEKRRLEARIAQL-------------EEELEEEQGNMEAMSDRVRKATQQ 1772
Query: 202 VTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-----GATGAYRARALELEAEVAE 256
L +L+ ER E + ++N EL +L +++ LEA++A+
Sbjct: 1773 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1832
Query: 257 MRQMLQSE 264
+ + ++ E
Sbjct: 1833 LEEQVEQE 1840
Score = 34.7 bits (78), Expect = 0.18
Identities = 31/120 (25%), Positives = 60/120 (50%), Gaps = 10/120 (8%)
Query: 39 LDRNTELEDSVQQMYTTNQEQL-QEIEYLTKQVELLRQMNEQHAKVYE-------QLDVT 90
L+ E E +Q T + +Q ++++ + QVE R+M EQ+ + E QL
Sbjct: 1833 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892
Query: 91 ARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSG--QGRRSPGK 148
E EE +Q++ A+ + Q+++ TE+ E + ++ L+S++ + RRS G+
Sbjct: 1893 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGR 1952
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 52.4 bits (124), Expect = 8e-07
Identities = 83/395 (21%), Positives = 160/395 (40%), Gaps = 50/395 (12%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQL-------AAELGKTLLDRNTELEDSVQQMYTT 55
AEN ++E E K + + LQ+ LQ A E+ L + ELE+ + +M
Sbjct: 878 AENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM--- 934
Query: 56 NQEQLQEIEYLTKQVELLR-QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILS 114
+ +L+E E +Q++ R +M +Q + EQL+ E E QKL + ++ KI
Sbjct: 935 -EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAARQKLQLEKVTAEAKIKK 989
Query: 115 LTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD 174
L + I + + L S+ +L + ++E+ A + LK ++
Sbjct: 990 LEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-------- 1040
Query: 175 HVFAEKITSLQGQPSPDEEENEHLKK--------------TVTMLQAQLSLERQKRVTME 220
I+ L+ + +E+ + L+K + LQAQ++ + + E
Sbjct: 1041 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 221 EEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLY 280
EE L + L+ ++ + ELE ++++++ L SE N EK D
Sbjct: 1097 EELQAAL---ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD--L 1151
Query: 281 VPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQ 340
E ++ LE+ + KR T+L A + + HE ++ +
Sbjct: 1152 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK-ALDEETRSHEAQ-VQEMRQKHA 1209
Query: 341 RGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLS 375
+ + L E Q+ K ++ + ++E L+
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1244
Score = 50.1 bits (118), Expect = 4e-06
Identities = 95/420 (22%), Positives = 162/420 (38%), Gaps = 57/420 (13%)
Query: 5 NLVEEFEM--KEDEPWYDHQDLQQDLQLAAELGKTLLDR--NTELEDSVQQMYTTNQEQL 60
+L EE E E E D QQ+L+ E T+L + + E Q+ Q+
Sbjct: 1150 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 61 QEIEYLTKQVELLRQ-----------MNEQHAKVYEQLDVTAR---ELEETNQKLVADSK 106
Q +E LT+Q+E ++ + +++A + +L V + E+E +KL A +
Sbjct: 1210 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1269
Query: 107 ASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYD 166
Q K L + LQ++VE + +G + GK K A A L
Sbjct: 1270 ELQSKCSDGERARAELNDKVHKLQNEVESV--TGMLNEAEGKAI--KLAKDVASLSSQLQ 1325
Query: 167 LRQHFVYDHV------------FAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQ 214
Q + + E+ SLQ Q + E ++L++ ++ L QLS ++
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 215 KR-------VTMEEEYGLVLKENSELEQQ----LGATGAYRARALELEAEVAEMRQMLQS 263
K +EE KE L QQ A L+ E+ ++ L +
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 264 EHPFVNGVEKLVP--DSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGS 321
+ V+ +EK D L K S +E E+ K K S + +L +
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS---LARALEEA 1502
Query: 322 DIVKGHEETCIRRAKAVKQRGISL-------LHEVDTQYSALKVKYEELLKKCQEEQDSL 374
K E + KA + +S +HE++ AL+ + EE+ + +E +D L
Sbjct: 1503 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 45.8 bits (107), Expect = 8e-05
Identities = 90/441 (20%), Positives = 181/441 (41%), Gaps = 66/441 (14%)
Query: 23 DLQQDLQLAAELGKTL--LDRNTELEDSVQQMYTTNQE--QLQEIEYLTKQVELLRQMNE 78
DL QL + L K D+ E ++ Y ++ + + E TK + L R + E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL-E 1500
Query: 79 QHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS 138
+ + E+L+ T + L+ + LV+ + + L ++ L+T ++ +++Q+EEL
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL-- 1558
Query: 139 SGQGRRSPGKCDQEKPAPSFACLK---ELYDLRQHFVYDHVFAEKITSLQGQPSPDEEEN 195
+ E A A L+ + L+ F D LQ + +EE+
Sbjct: 1559 -----------EDELQATEDAKLRLEVNMQALKGQFERD---------LQARDEQNEEKR 1598
Query: 196 EHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVA 255
L++ + + +L ER++R + + +LE Q A A + R E +
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGR----EEAIK 1652
Query: 256 EMRQMLQSEHPFVNGVE--KLVPDSLYVPFKE---PSQSLLEEMF-----LTVPESHRKP 305
++R++ F +E + D ++ KE ++SL ++ L E RK
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712
Query: 306 L---KRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEE 362
K +E + SSL+G + ++ + RR +A R L E++ + ++ +
Sbjct: 1713 ADLEKEELAEELASSLSGRNALQDEK----RRLEA---RIAQLEEELEEEQGNMEAMSDR 1765
Query: 363 LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEY 422
+ K Q+ + + A + S A + +A+ + EL S E +
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNE----SARQQLERQNKELRSKLHEMEGA------V 1815
Query: 423 KALFKEIFSCIKKTKQEIDEQ 443
K+ FK + ++ +++EQ
Sbjct: 1816 KSKFKSTIAALEAKIAQLEEQ 1836
Score = 45.4 bits (106), Expect = 1e-04
Identities = 102/457 (22%), Positives = 194/457 (42%), Gaps = 70/457 (15%)
Query: 8 EEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLT 67
EE + KEDE Q ++ Q A K L ++++L + + QEQLQ L
Sbjct: 859 EEMQAKEDEL----QKTKERQQKAENELKELEQKHSQLTEEKNLL----QEQLQAETELY 910
Query: 68 KQVELLR----QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ E +R ++ ++ +++ E E+ Q+L A+ K Q++L L E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE------ 964
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD--------- 174
Q+EE +++ Q K EK + A +K+L D + V D
Sbjct: 965 --------QLEEEEAARQ------KLQLEK-VTAEAKIKKLED--EILVMDDQNNKLSKE 1007
Query: 175 -HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSEL 233
+ E+I+ L + +EE+ ++L K ++ +S E + R+ EE+ +E +L
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS-ELEVRLKKEEK---SRQELEKL 1063
Query: 234 EQQL-GATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLE 292
+++L G + + +L+A++AE++ L + + + D + K + +
Sbjct: 1064 KRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE--IAQKNNALKKIR 1121
Query: 293 EMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQ 352
E+ E H L+ E + S A + + + +A+K L TQ
Sbjct: 1122 EL-----EGHISDLQ----EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1172
Query: 353 YSALKVKYEE---LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVN 409
L+ K E+ +LKK +E ++ SH+A Q K V +E + ++ A N
Sbjct: 1173 -QELRAKREQEVTVLKKALDE-ETRSHEA-QVQEMRQKHAQAVEELTEQLEQ-FKRAKAN 1228
Query: 410 PEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTK 446
+ + T E L E+ + + KQE++ ++ K
Sbjct: 1229 LDK-NKQTLEKENADLAGEL-RVLGQAKQEVEHKKKK 1263
Score = 36.6 bits (83), Expect = 0.048
Identities = 48/248 (19%), Positives = 100/248 (40%), Gaps = 25/248 (10%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
+D ++ LAA K L +LE +E ++++ L Q++ ++ E
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 82 KVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQ 141
+++ TA+E E+ + L AD Q+ + + + Q +++ + EEL SS
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEK-EELAEELASSLS 1729
Query: 142 GRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKT 201
GR + Q++ A + +L E++ QG + +
Sbjct: 1730 GRNAL----QDEKRRLEARIAQL-------------EEELEEEQGNMEAMSDRVRKATQQ 1772
Query: 202 VTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-----GATGAYRARALELEAEVAE 256
L +L+ ER E + ++N EL +L +++ LEA++A+
Sbjct: 1773 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1832
Query: 257 MRQMLQSE 264
+ + ++ E
Sbjct: 1833 LEEQVEQE 1840
Score = 33.5 bits (75), Expect = 0.41
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 39 LDRNTELEDSVQQMYTTNQEQL-QEIEYLTKQVELLRQMNEQHAKVYE-------QLDVT 90
L+ E E +Q T + +Q ++++ + QVE R+M EQ+ + E QL
Sbjct: 1833 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892
Query: 91 ARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQV 133
E EE +Q++ A+ + Q+++ TE+ E + ++ L+S++
Sbjct: 1893 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 52.4 bits (124), Expect = 8e-07
Identities = 83/395 (21%), Positives = 160/395 (40%), Gaps = 50/395 (12%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQL-------AAELGKTLLDRNTELEDSVQQMYTT 55
AEN ++E E K + + LQ+ LQ A E+ L + ELE+ + +M
Sbjct: 871 AENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM--- 927
Query: 56 NQEQLQEIEYLTKQVELLR-QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILS 114
+ +L+E E +Q++ R +M +Q + EQL+ E E QKL + ++ KI
Sbjct: 928 -EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE----EEEAARQKLQLEKVTAEAKIKK 982
Query: 115 LTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD 174
L + I + + L S+ +L + ++E+ A + LK ++
Sbjct: 983 LEDEILVMDDQNNKL-SKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE-------- 1033
Query: 175 HVFAEKITSLQGQPSPDEEENEHLKK--------------TVTMLQAQLSLERQKRVTME 220
I+ L+ + +E+ + L+K + LQAQ++ + + E
Sbjct: 1034 ----SMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 221 EEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLY 280
EE L + L+ ++ + ELE ++++++ L SE N EK D
Sbjct: 1090 EELQAAL---ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD--L 1144
Query: 281 VPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQ 340
E ++ LE+ + KR T+L A + + HE ++ +
Sbjct: 1145 GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK-ALDEETRSHEAQ-VQEMRQKHA 1202
Query: 341 RGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLS 375
+ + L E Q+ K ++ + ++E L+
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLA 1237
Score = 50.1 bits (118), Expect = 4e-06
Identities = 95/420 (22%), Positives = 162/420 (38%), Gaps = 57/420 (13%)
Query: 5 NLVEEFEM--KEDEPWYDHQDLQQDLQLAAELGKTLLDR--NTELEDSVQQMYTTNQEQL 60
+L EE E E E D QQ+L+ E T+L + + E Q+ Q+
Sbjct: 1143 DLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 61 QEIEYLTKQVELLRQ-----------MNEQHAKVYEQLDVTAR---ELEETNQKLVADSK 106
Q +E LT+Q+E ++ + +++A + +L V + E+E +KL A +
Sbjct: 1203 QAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
Query: 107 ASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYD 166
Q K L + LQ++VE + +G + GK K A A L
Sbjct: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESV--TGMLNEAEGKAI--KLAKDVASLSSQLQ 1318
Query: 167 LRQHFVYDHV------------FAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQ 214
Q + + E+ SLQ Q + E ++L++ ++ L QLS ++
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 215 KR-------VTMEEEYGLVLKENSELEQQ----LGATGAYRARALELEAEVAEMRQMLQS 263
K +EE KE L QQ A L+ E+ ++ L +
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 264 EHPFVNGVEKLVP--DSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGS 321
+ V+ +EK D L K S +E E+ K K S + +L +
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS---LARALEEA 1495
Query: 322 DIVKGHEETCIRRAKAVKQRGISL-------LHEVDTQYSALKVKYEELLKKCQEEQDSL 374
K E + KA + +S +HE++ AL+ + EE+ + +E +D L
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 45.8 bits (107), Expect = 8e-05
Identities = 90/441 (20%), Positives = 181/441 (41%), Gaps = 66/441 (14%)
Query: 23 DLQQDLQLAAELGKTL--LDRNTELEDSVQQMYTTNQE--QLQEIEYLTKQVELLRQMNE 78
DL QL + L K D+ E ++ Y ++ + + E TK + L R + E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARAL-E 1493
Query: 79 QHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS 138
+ + E+L+ T + L+ + LV+ + + L ++ L+T ++ +++Q+EEL
Sbjct: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL-- 1551
Query: 139 SGQGRRSPGKCDQEKPAPSFACLK---ELYDLRQHFVYDHVFAEKITSLQGQPSPDEEEN 195
+ E A A L+ + L+ F D LQ + +EE+
Sbjct: 1552 -----------EDELQATEDAKLRLEVNMQALKGQFERD---------LQARDEQNEEKR 1591
Query: 196 EHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVA 255
L++ + + +L ER++R + + +LE Q A A + R E +
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQ--ADSAIKGR----EEAIK 1645
Query: 256 EMRQMLQSEHPFVNGVE--KLVPDSLYVPFKE---PSQSLLEEMF-----LTVPESHRKP 305
++R++ F +E + D ++ KE ++SL ++ L E RK
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
Query: 306 L---KRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEE 362
K +E + SSL+G + ++ + RR +A R L E++ + ++ +
Sbjct: 1706 ADLEKEELAEELASSLSGRNALQDEK----RRLEA---RIAQLEEELEEEQGNMEAMSDR 1758
Query: 363 LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEY 422
+ K Q+ + + A + S A + +A+ + EL S E +
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNE----SARQQLERQNKELRSKLHEMEGA------V 1808
Query: 423 KALFKEIFSCIKKTKQEIDEQ 443
K+ FK + ++ +++EQ
Sbjct: 1809 KSKFKSTIAALEAKIAQLEEQ 1829
Score = 45.4 bits (106), Expect = 1e-04
Identities = 102/457 (22%), Positives = 194/457 (42%), Gaps = 70/457 (15%)
Query: 8 EEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLT 67
EE + KEDE Q ++ Q A K L ++++L + + QEQLQ L
Sbjct: 852 EEMQAKEDEL----QKTKERQQKAENELKELEQKHSQLTEEKNLL----QEQLQAETELY 903
Query: 68 KQVELLR----QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ E +R ++ ++ +++ E E+ Q+L A+ K Q++L L E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE------ 957
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD--------- 174
Q+EE +++ Q K EK + A +K+L D + V D
Sbjct: 958 --------QLEEEEAARQ------KLQLEK-VTAEAKIKKLED--EILVMDDQNNKLSKE 1000
Query: 175 -HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSEL 233
+ E+I+ L + +EE+ ++L K ++ +S E + R+ EE+ +E +L
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS-ELEVRLKKEEK---SRQELEKL 1056
Query: 234 EQQL-GATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLE 292
+++L G + + +L+A++AE++ L + + + D + K + +
Sbjct: 1057 KRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE--IAQKNNALKKIR 1114
Query: 293 EMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQ 352
E+ E H L+ E + S A + + + +A+K L TQ
Sbjct: 1115 EL-----EGHISDLQ----EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1165
Query: 353 YSALKVKYEE---LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVN 409
L+ K E+ +LKK +E ++ SH+A Q K V +E + ++ A N
Sbjct: 1166 -QELRAKREQEVTVLKKALDE-ETRSHEA-QVQEMRQKHAQAVEELTEQLEQ-FKRAKAN 1221
Query: 410 PEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTK 446
+ + T E L E+ + + KQE++ ++ K
Sbjct: 1222 LDK-NKQTLEKENADLAGEL-RVLGQAKQEVEHKKKK 1256
Score = 36.6 bits (83), Expect = 0.048
Identities = 48/248 (19%), Positives = 100/248 (40%), Gaps = 25/248 (10%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
+D ++ LAA K L +LE +E ++++ L Q++ ++ E
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 82 KVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQ 141
+++ TA+E E+ + L AD Q+ + + + Q +++ + EEL SS
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK--QADLEK-EELAEELASSLS 1722
Query: 142 GRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKT 201
GR + Q++ A + +L E++ QG + +
Sbjct: 1723 GRNAL----QDEKRRLEARIAQL-------------EEELEEEQGNMEAMSDRVRKATQQ 1765
Query: 202 VTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQL-----GATGAYRARALELEAEVAE 256
L +L+ ER E + ++N EL +L +++ LEA++A+
Sbjct: 1766 AEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825
Query: 257 MRQMLQSE 264
+ + ++ E
Sbjct: 1826 LEEQVEQE 1833
Score = 33.5 bits (75), Expect = 0.41
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 8/103 (7%)
Query: 39 LDRNTELEDSVQQMYTTNQEQL-QEIEYLTKQVELLRQMNEQHAKVYE-------QLDVT 90
L+ E E +Q T + +Q ++++ + QVE R+M EQ+ + E QL
Sbjct: 1826 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
Query: 91 ARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQV 133
E EE +Q++ A+ + Q+++ TE+ E + ++ L+S++
Sbjct: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 52.4 bits (124), Expect = 8e-07
Identities = 101/474 (21%), Positives = 194/474 (40%), Gaps = 73/474 (15%)
Query: 11 EMKEDEPWYDHQDLQQDLQLAAELGK--TLLDRNTELEDSVQQMYTTNQEQLQ----EIE 64
++KE+ Q+ +D QL A LG ++L + ED+ +++ +++L+ +I+
Sbjct: 365 QLKEEVSHLKSQNKDKDHQLEA-LGSRCSVLKEELKQEDAHRELREAQEKELKLCKTQIQ 423
Query: 65 YLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQT 124
+ K+++ LR + + T RE + +KL DS+ ++ + ++
Sbjct: 424 DMEKEMKKLRAELRKSCTEQSVISRTLREKSKVEEKLQEDSRRKLLQLQEMGNRESVIKI 483
Query: 125 NIDHLQSQVEELKS----SGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEK 180
N++ Q+E +S + GR P + +KP V D EK
Sbjct: 484 NLERAVGQLEHFRSQVIKATYGRAKPFR---DKP-----------------VTDQQLIEK 523
Query: 181 ITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT 240
IT + ++ N KK + QLS +Q+ T E K + L+ A
Sbjct: 524 ITQV-----TEDNINFQQKKWTLQKETQLSNSKQEETTENIE-----KLRTSLD-SCQAC 572
Query: 241 GAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSL--YVPFKEPSQSLLEEMFLTV 298
+ +L+ EV ++ Q LQ P V+G++K+V D L + + E + LL ++ +
Sbjct: 573 MKISCCSHDLKKEV-DLLQHLQVSPP-VSGLQKVVLDVLRHALSWLEEVEQLLRDLGILP 630
Query: 299 PESHRKPLKRSSSETIL---SSLAGSDIVKGHEETCIRRAKAVKQR----------GISL 345
++ +++ S + + AG+ +G E RA+ Q G +L
Sbjct: 631 SSPNKDQVQQFSGNSAVFTAGKAAGASGREGEAERGEARARGEAQSQNQATDGREGGKAL 690
Query: 346 LHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLT--------GVNAQSE 397
+ + + K EE K+ QE + L+ Q +A AK +T + +
Sbjct: 691 EEYITQERNRAKETLEEERKRMQELESLLA----QQKKALAKSITQEKNRVKEALEEEQT 746
Query: 398 PVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRSLS 451
V E + E + S + KA KE K+ Q+++ T+ + +S
Sbjct: 747 RVQELEERLARQKEVLESSIAHEKRKA--KEALESEKRKVQDLENHLTQQKEIS 798
Score = 37.4 bits (85), Expect = 0.028
Identities = 71/347 (20%), Positives = 129/347 (37%), Gaps = 48/347 (13%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELED-SVQQMYTTNQEQLQE 62
E+ + + K E + QDL+ K + + N E ++ ++++Q+
Sbjct: 763 ESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQD 822
Query: 63 IEY-LTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIEC 121
+E LTKQ E L ++ + +L +EET + +S ++ L L ET+
Sbjct: 823 LENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAE 882
Query: 122 LQTN-----------------IDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKE- 163
L+T + LQ + E + + K ++ A + L+E
Sbjct: 883 LETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTIVSLEEK 942
Query: 164 LYDLRQHFVYDHVFAEKITSLQGQPSPDEEE------------------NEHLKKTVTML 205
L + QH + + E T P+P EE EHL +
Sbjct: 943 LQKVTQH--HKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDLLAA 1000
Query: 206 QAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEH 265
Q ++ +++ + + ++ S+L +L + +ELE V ++Q QS+
Sbjct: 1001 QKEILSQQEVIMKLRKDLTEAHSRMSDLRGELN-----EKQKMELEQNVVLVQQ--QSKE 1053
Query: 266 PFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSE 312
V EK+ S V K+ LEE E HR L +
Sbjct: 1054 LSVL-KEKMAQMSSLVEKKDRELKALEEALRASQEKHRLQLNTEKEQ 1099
Score = 35.8 bits (81), Expect = 0.082
Identities = 76/421 (18%), Positives = 168/421 (39%), Gaps = 41/421 (9%)
Query: 2 LAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQ 61
L E + +E ++ + + +Q+ L A+ K L T+ ++ V++ Q ++Q
Sbjct: 690 LEEYITQERNRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQ 749
Query: 62 EI-EYLTKQVELLR-QMNEQHAKVYEQLDVTARELEE-----TNQKLVADSKASQQKILS 114
E+ E L +Q E+L + + K E L+ R++++ T QK +++S + +K
Sbjct: 750 ELEERLARQKEVLESSIAHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEK-RK 808
Query: 115 LTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD 174
E +E + + L++++ + K + + K + + A ++E +
Sbjct: 809 AKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKA----- 863
Query: 175 HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELE 234
+ K SL + + E E K + M++ +L L+++ +++E + E
Sbjct: 864 -TESLKAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDEQE---SQRHGFE 919
Query: 235 QQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEM 294
+++ + + + E Q + H + G + D+ P +E Q L
Sbjct: 920 EEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLV-- 977
Query: 295 FLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYS 354
P+ SS++ + D++ +E ++ +K R L E ++ S
Sbjct: 978 ---------APMTESSAKDMAYEHLIDDLLAAQKEILSQQEVIMKLR--KDLTEAHSRMS 1026
Query: 355 ALKVKYEE-----------LLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGW 403
L+ + E L+++ +E L K Q S K + A E + +
Sbjct: 1027 DLRGELNEKQKMELEQNVVLVQQQSKELSVLKEKMAQMSSLVEKKDRELKALEEALRASQ 1086
Query: 404 E 404
E
Sbjct: 1087 E 1087
Score = 33.9 bits (76), Expect = 0.31
Identities = 47/203 (23%), Positives = 89/203 (43%), Gaps = 20/203 (9%)
Query: 81 AKVYEQLDVTARELEETNQKLVAD-SKASQQKILSLTET--IECLQTNIDHLQSQVEELK 137
A++Y + D+ ++ +E L + S+ S +I S + I LQ + L +V E
Sbjct: 213 AEIYVEEDLAQQDKDEIILLLGKEVSRLSDYEIESKYKDVIIANLQNEVAELSQKVSETT 272
Query: 138 SSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFV-----YDHVFAEKITSLQGQPSPDE 192
+S Q + + Q A KE+ L+ Y V + ++ + + +
Sbjct: 273 TSRQNEKEISQKCQVLDEDIDAKQKEIQSLKSQISALQKGYSKVLCQTLSERNSEITSLK 332
Query: 193 EENEHLKKT-------VTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRA 245
E E+LK+ V+ LQ + + ++ ++EE + +N + + QL A G+ R
Sbjct: 333 NEGENLKRDNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQLEALGS-RC 391
Query: 246 RAL--ELEAEVA--EMRQMLQSE 264
L EL+ E A E+R+ + E
Sbjct: 392 SVLKEELKQEDAHRELREAQEKE 414
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 51.6 bits (122), Expect = 1e-06
Identities = 90/394 (22%), Positives = 162/394 (41%), Gaps = 53/394 (13%)
Query: 29 QLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQL- 87
Q+ AE+ L N L D+V TTNQ + +KQ L ++ + +A++ +L
Sbjct: 414 QMEAEIAH-LKQENGILRDAVSN--TTNQLE-------SKQSAELNKLRQDYARLVNELT 463
Query: 88 DVTARELEETNQKLVADSKASQQKIL------SLTETIECLQTNIDHLQSQVEELKSSGQ 141
+ T + +E QK A+ A+Q K+ E ++ ++ ++L+S
Sbjct: 464 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 523
Query: 142 GRRSPGKCDQEKPAPSFACLKELYD-LRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKK 200
+ + + K + ++L L Q + K SLQ Q E+NE LK
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 201 TVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALE----------- 249
+ +Q++ + V EE + ++ +++ +++Q + + R R
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 643
Query: 250 ---LEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMF----------L 296
L+AEV +++ + + + +EK+ S+YV K+ LLEE
Sbjct: 644 NFLLKAEVQKLQALANEQAAAAHELEKM-QQSVYV--KDDKIRLLEEQLQHEISNKMEEF 700
Query: 297 TVPESHRKPLKR--SSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYS 354
+ K LK +T++S D+V+ E CI+ K K + + L E
Sbjct: 701 KILNDQNKALKSEVQKLQTLVSEQPNKDVVE-QMEKCIQE-KDEKLKTVEELLETGLIQV 758
Query: 355 ALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKD 388
A K EE L + E SL+ K VQ +A D
Sbjct: 759 ATK---EEELNAIRTENSSLT-KEVQDLKAKQND 788
Score = 46.6 bits (109), Expect = 5e-05
Identities = 76/333 (22%), Positives = 134/333 (40%), Gaps = 60/333 (18%)
Query: 3 AENLVEEFEMKEDEPWYDHQDLQQDLQ------------LAAELGKTLLDRNTELEDSVQ 50
AE EE + + +H+ QQDLQ L ++L TL+ + +LE +
Sbjct: 493 AERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQ-QLEQRLM 551
Query: 51 QMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADS--KAS 108
Q+ + Q+++ + E L QV+ + + NE +Q ++ +T+ ++A+ K
Sbjct: 552 QLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFH--SQIAAQTSASVLAEELHKVI 609
Query: 109 QQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEK----PAPSFACLKEL 164
+K + +T + L + D L S+ EELK Q K + +K A EL
Sbjct: 610 AEKDKQIKQTEDSLASERDRLTSKEEELKDI-QNMNFLLKAEVQKLQALANEQAAAAHEL 668
Query: 165 YDLRQH-FVYDHVFAEKITSLQGQPSPDEEE-------NEHLKKTVTMLQAQLSLERQKR 216
++Q +V D LQ + S EE N+ LK V LQ +S + K
Sbjct: 669 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKD 728
Query: 217 V------------------------------TMEEEYGLVLKENSELEQQLGATGAYRAR 246
V T EEE + ENS L +++ A +
Sbjct: 729 VVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQND 788
Query: 247 ALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSL 279
+ + V E+++++ + + VE+L+ L
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAEL 821
Score = 45.4 bits (106), Expect = 1e-04
Identities = 101/487 (20%), Positives = 192/487 (39%), Gaps = 55/487 (11%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEI 63
E + + +K+D+ + LQ ++ E K L D+N L+ VQ++ T EQ
Sbjct: 669 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN-- 726
Query: 64 EYLTKQVELLRQMNEQHAKVYEQLDVT-----ARELEETN---------QKLVADSKASQ 109
+ + +Q+E Q ++ K E+L T A + EE N K V D KA Q
Sbjct: 727 KDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQ 786
Query: 110 QKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFAC-LKELYDL- 167
+S +E L+ I +++ ++ + ++ S ++EL +L
Sbjct: 787 NDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLL 846
Query: 168 ----RQHFVYDHVFAEKITSL--QGQPSPD-EEENEHLKKTVTMLQAQLSLERQKRVTME 220
Q V EK L G+ D +EENE LK V + AQ +L+ +
Sbjct: 847 KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEV-AQHNLKEASSASQF 905
Query: 221 EEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLY 280
EE +VLKE ++L A + R +L ++ ++ + F + +E+L +
Sbjct: 906 EELEIVLKEKENELKRLEA--MLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQN-- 961
Query: 281 VPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHE------------ 328
+++ S E L V K + +E L SL D V+
Sbjct: 962 --YQQASSFPPHEELLKVISEREKEISGLWNE--LDSL--KDAVEHQRKKNNDLREKNWE 1015
Query: 329 --ETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQT----- 381
E K ++ + E Q A++++ +E+LKK + S+ +
Sbjct: 1016 AMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGF 1075
Query: 382 SRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEID 441
+ A + + G + E +L + +YK++ E ++K ++ ++
Sbjct: 1076 EKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVE 1135
Query: 442 EQRTKYR 448
++ K++
Sbjct: 1136 QEENKWK 1142
Score = 42.0 bits (97), Expect = 0.001
Identities = 106/482 (21%), Positives = 183/482 (37%), Gaps = 69/482 (14%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
Q+LQ L+ E T+ E E + Q+ +E E L V+ + Q N + A
Sbjct: 840 QELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEA 899
Query: 82 KV---YEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKS 138
+E+L++ +E E ++L A K + + S T+ ++ +Q +SQ+E+LK
Sbjct: 900 SSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQ 959
Query: 139 SGQGRRSPG-------KCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPD 191
+ S K E+ EL L+ + +K L+ +
Sbjct: 960 QNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQR---KKNNDLR---EKN 1013
Query: 192 EEENEHLKKTVTMLQAQL---SLERQKRV-TMEEEYGLVLK------------------- 228
E E L T MLQ ++ S ERQ++V +E E VLK
Sbjct: 1014 WEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLH 1073
Query: 229 --ENSELEQQLGATGAYRARALELE-AEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKE 285
E E G +G+ + LE + E EM +LQ E V + + +
Sbjct: 1074 GFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSV-LAETEGILQKLQR 1132
Query: 286 PSQSLLEEMFLTVPESHR--KPLKRS--SSETILSSLAG-----SDIVKGHEETCIRRAK 336
+ + + V ESH+ K ++ S SSE L L ++ + E + K
Sbjct: 1133 SVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEK 1192
Query: 337 AVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLS------HKAVQTSRAAAKDLT 390
A +R + T+ LK + E L K + EQ+ HKA Q+ +
Sbjct: 1193 AEMERSTYV-----TEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIV 1247
Query: 391 GVNAQSEPVASGWELASVNPEPVSS--PTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYR 448
+ + E + V+PE SS T ++ ++ Q++ +++ Y+
Sbjct: 1248 KAAGDTTVI----ENSDVSPETESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQ 1303
Query: 449 SL 450
L
Sbjct: 1304 VL 1305
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 51.6 bits (122), Expect = 1e-06
Identities = 90/394 (22%), Positives = 162/394 (41%), Gaps = 53/394 (13%)
Query: 29 QLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQL- 87
Q+ AE+ L N L D+V TTNQ + +KQ L ++ + +A++ +L
Sbjct: 414 QMEAEIAH-LKQENGILRDAVSN--TTNQLE-------SKQSAELNKLRQDYARLVNELT 463
Query: 88 DVTARELEETNQKLVADSKASQQKIL------SLTETIECLQTNIDHLQSQVEELKSSGQ 141
+ T + +E QK A+ A+Q K+ E ++ ++ ++L+S
Sbjct: 464 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 523
Query: 142 GRRSPGKCDQEKPAPSFACLKELYD-LRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKK 200
+ + + K + ++L L Q + K SLQ Q E+NE LK
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 201 TVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALE----------- 249
+ +Q++ + V EE + ++ +++ +++Q + + R R
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 643
Query: 250 ---LEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMF----------L 296
L+AEV +++ + + + +EK+ S+YV K+ LLEE
Sbjct: 644 NFLLKAEVQKLQALANEQAAAAHELEKM-QQSVYV--KDDKIRLLEEQLQHEISNKMEEF 700
Query: 297 TVPESHRKPLKR--SSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYS 354
+ K LK +T++S D+V+ E CI+ K K + + L E
Sbjct: 701 KILNDQNKALKSEVQKLQTLVSEQPNKDVVE-QMEKCIQE-KDEKLKTVEELLETGLIQV 758
Query: 355 ALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKD 388
A K EE L + E SL+ K VQ +A D
Sbjct: 759 ATK---EEELNAIRTENSSLT-KEVQDLKAKQND 788
Score = 47.0 bits (110), Expect = 4e-05
Identities = 78/382 (20%), Positives = 162/382 (42%), Gaps = 72/382 (18%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEI 63
E + + +K+D+ + LQ ++ E K L D+N L+ VQ++ T EQ
Sbjct: 669 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN-- 726
Query: 64 EYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ + +Q+E Q ++ K T EL ET VA + E + ++
Sbjct: 727 KDVVEQMEKCIQEKDEKLK-------TVEELLETGLIQVATKE----------EELNAIR 769
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITS 183
T L +V++LK+ ++ SFA L E +L++
Sbjct: 770 TENSSLTKEVQDLKA------------KQNDQVSFASLVE--ELKKVI------------ 803
Query: 184 LQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAY 243
E++ +K +L+A+L K T+++ + +E L++++G
Sbjct: 804 --------HEKDGKIKSVEELLEAELLKVANKEKTVQD----LKQEIKALKEEIGNVQLE 851
Query: 244 RARALELEAEVAEMRQMLQSEHPFVNGVEKLVPD-----SLYVPFKEPSQSLLEEMFLTV 298
+A+ L + ++V E++ +L+ + +N ++ ++ + + + + Q E + V
Sbjct: 852 KAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV 911
Query: 299 PESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKA-VKQR------GISLLHEVDT 351
E + LK +SS + L +IV +E ++R +A +K+R LL +V
Sbjct: 912 QEVAQHNLKEASSASQFEEL---EIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Query: 352 QYSALKVKYEELLKKCQEEQDS 373
+ K + E+L ++ ++ S
Sbjct: 969 ENKLFKSQIEQLKQQNYQQASS 990
Score = 41.6 bits (96), Expect = 0.001
Identities = 100/493 (20%), Positives = 187/493 (37%), Gaps = 90/493 (18%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQ-LAAELGKTLLDRNTEL----------------E 46
E L+E +K QDL+Q+++ L E+G L++ +L E
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Query: 47 DSVQQMYTTNQEQLQEIEYLTKQVELLRQMNE----------QH-------AKVYEQLDV 89
+ + M +E+ +++ K ++ L++ NE QH A +E+L++
Sbjct: 874 EQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI 933
Query: 90 TARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKC 149
+E E ++L A K + + S T+ ++ +Q +SQ+E+LK + S
Sbjct: 934 VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP 993
Query: 150 DQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLK-KTVTMLQAQ 208
+E KE+ L ++ SL+ ++N L+ K ++A
Sbjct: 994 HEELLKVISEREKEISGL----------WNELDSLKDAVEHQRKKNNDLREKNWEAMEAL 1043
Query: 209 LSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHP-- 266
S E+ + V K + E +QQ+ A+ELEA+ + + P
Sbjct: 1044 ASTEKMLQ-------DKVNKTSKERQQQV--------EAVELEAKEVLKKLFPKVSVPSN 1088
Query: 267 -----FVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGS 321
+++G EK + + +LE E H L + E S LA
Sbjct: 1089 LSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMH--TLLQLECEKYKSVLA-- 1144
Query: 322 DIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSL--SHKAV 379
+ + Q+ L V+ + + KVK +E K ++ Q S S + +
Sbjct: 1145 ------------ETEGILQK---LQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQEL 1189
Query: 380 QTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQE 439
+ R+ KD+ + + E + EL E + T E K L E+ + + E
Sbjct: 1190 ERLRSENKDIENLRREREHLE--MELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSE 1247
Query: 440 IDEQRTKYRSLSS 452
Q + L +
Sbjct: 1248 AVRQNEELNLLKA 1260
Score = 35.4 bits (80), Expect = 0.11
Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 14/214 (6%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
Q LQ+ ++ K +D + + +Q +T+++++L+ + K +E LR+ E
Sbjct: 1151 QKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLE 1210
Query: 82 KVYEQLDVT-------ARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVE 134
E+ ++ REL++ +L S + + E + L+ ++ +++
Sbjct: 1211 MELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLR 1270
Query: 135 ELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEE 194
+ Q R D K S ++ + + V S + + S E
Sbjct: 1271 ----TEQNERQKVAGDLHKAQQSLELIQS--KIVKAAGDTTVIENSDVSPETESSEKETM 1324
Query: 195 NEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLK 228
+ L +TVT LQ L Q ++T E+E+ VL+
Sbjct: 1325 SVSLNQTVTQLQQLLQAVNQ-QLTKEKEHYQVLE 1357
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 51.6 bits (122), Expect = 1e-06
Identities = 90/394 (22%), Positives = 162/394 (41%), Gaps = 53/394 (13%)
Query: 29 QLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQL- 87
Q+ AE+ L N L D+V TTNQ + +KQ L ++ + +A++ +L
Sbjct: 414 QMEAEIAH-LKQENGILRDAVSN--TTNQLE-------SKQSAELNKLRQDYARLVNELT 463
Query: 88 DVTARELEETNQKLVADSKASQQKIL------SLTETIECLQTNIDHLQSQVEELKSSGQ 141
+ T + +E QK A+ A+Q K+ E ++ ++ ++L+S
Sbjct: 464 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 523
Query: 142 GRRSPGKCDQEKPAPSFACLKELYD-LRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKK 200
+ + + K + ++L L Q + K SLQ Q E+NE LK
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 201 TVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALE----------- 249
+ +Q++ + V EE + ++ +++ +++Q + + R R
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 643
Query: 250 ---LEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMF----------L 296
L+AEV +++ + + + +EK+ S+YV K+ LLEE
Sbjct: 644 NFLLKAEVQKLQALANEQAAAAHELEKM-QQSVYV--KDDKIRLLEEQLQHEISNKMEEF 700
Query: 297 TVPESHRKPLKR--SSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYS 354
+ K LK +T++S D+V+ E CI+ K K + + L E
Sbjct: 701 KILNDQNKALKSEVQKLQTLVSEQPNKDVVE-QMEKCIQE-KDEKLKTVEELLETGLIQV 758
Query: 355 ALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKD 388
A K EE L + E SL+ K VQ +A D
Sbjct: 759 ATK---EEELNAIRTENSSLT-KEVQDLKAKQND 788
Score = 47.0 bits (110), Expect = 4e-05
Identities = 78/382 (20%), Positives = 162/382 (42%), Gaps = 72/382 (18%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEI 63
E + + +K+D+ + LQ ++ E K L D+N L+ VQ++ T EQ
Sbjct: 669 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN-- 726
Query: 64 EYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ + +Q+E Q ++ K T EL ET VA + E + ++
Sbjct: 727 KDVVEQMEKCIQEKDEKLK-------TVEELLETGLIQVATKE----------EELNAIR 769
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITS 183
T L +V++LK+ ++ SFA L E +L++
Sbjct: 770 TENSSLTKEVQDLKA------------KQNDQVSFASLVE--ELKKVI------------ 803
Query: 184 LQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAY 243
E++ +K +L+A+L K T+++ + +E L++++G
Sbjct: 804 --------HEKDGKIKSVEELLEAELLKVANKEKTVQD----LKQEIKALKEEIGNVQLE 851
Query: 244 RARALELEAEVAEMRQMLQSEHPFVNGVEKLVPD-----SLYVPFKEPSQSLLEEMFLTV 298
+A+ L + ++V E++ +L+ + +N ++ ++ + + + + Q E + V
Sbjct: 852 KAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV 911
Query: 299 PESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKA-VKQR------GISLLHEVDT 351
E + LK +SS + L +IV +E ++R +A +K+R LL +V
Sbjct: 912 QEVAQHNLKEASSASQFEEL---EIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Query: 352 QYSALKVKYEELLKKCQEEQDS 373
+ K + E+L ++ ++ S
Sbjct: 969 ENKLFKSQIEQLKQQNYQQASS 990
Score = 43.1 bits (100), Expect = 5e-04
Identities = 105/508 (20%), Positives = 191/508 (37%), Gaps = 83/508 (16%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQ-LAAELGKTLLDRNTEL----------------E 46
E L+E +K QDL+Q+++ L E+G L++ +L E
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Query: 47 DSVQQMYTTNQEQLQEIEYLTKQVELLRQMNE----------QH-------AKVYEQLDV 89
+ + M +E+ +++ K ++ L++ NE QH A +E+L++
Sbjct: 874 EQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI 933
Query: 90 TARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPG-- 147
+E E ++L A K + + S T+ ++ +Q +SQ+E+LK + S
Sbjct: 934 VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP 993
Query: 148 -----KCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTV 202
K E+ EL L+ +H + Q + + E E LKK
Sbjct: 994 HEELLKVISEREKEISGLWNELDSLKD--AVEHQRKKNNERQQQVEAVELEAKEVLKKLF 1051
Query: 203 TMLQAQLSLERQKRVTMEEEYGLVLK--ENSELEQQLGATGAYRARALELE-AEVAEMRQ 259
+ +L YG L E E G +G+ + LE + E EM
Sbjct: 1052 PKVSVPSNL----------SYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHT 1101
Query: 260 MLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHR--KPLKRS--SSETIL 315
+LQ E V + + + + + + V ESH+ K ++ S SSE L
Sbjct: 1102 LLQLECEKYKSV-LAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQEL 1160
Query: 316 SSLAG-----SDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEE 370
L ++ + E + KA +R + T+ LK + E L K + E
Sbjct: 1161 ERLRSENKDIENLRREREHLEMELEKAEMERSTYV-----TEVRELKAQLNETLTKLRTE 1215
Query: 371 QDSLS------HKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSS--PTTPPEY 422
Q+ HKA Q+ + + + E + V+PE SS T
Sbjct: 1216 QNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVI----ENSDVSPETESSEKETMSVSL 1271
Query: 423 KALFKEIFSCIKKTKQEIDEQRTKYRSL 450
++ ++ Q++ +++ Y+ L
Sbjct: 1272 NQTVTQLQQLLQAVNQQLTKEKEHYQVL 1299
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 51.6 bits (122), Expect = 1e-06
Identities = 90/394 (22%), Positives = 162/394 (41%), Gaps = 53/394 (13%)
Query: 29 QLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQL- 87
Q+ AE+ L N L D+V TTNQ + +KQ L ++ + +A++ +L
Sbjct: 414 QMEAEIAH-LKQENGILRDAVSN--TTNQLE-------SKQSAELNKLRQDYARLVNELT 463
Query: 88 DVTARELEETNQKLVADSKASQQKIL------SLTETIECLQTNIDHLQSQVEELKSSGQ 141
+ T + +E QK A+ A+Q K+ E ++ ++ ++L+S
Sbjct: 464 EKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFV 523
Query: 142 GRRSPGKCDQEKPAPSFACLKELYD-LRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKK 200
+ + + K + ++L L Q + K SLQ Q E+NE LK
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 201 TVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALE----------- 249
+ +Q++ + V EE + ++ +++ +++Q + + R R
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 643
Query: 250 ---LEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMF----------L 296
L+AEV +++ + + + +EK+ S+YV K+ LLEE
Sbjct: 644 NFLLKAEVQKLQALANEQAAAAHELEKM-QQSVYV--KDDKIRLLEEQLQHEISNKMEEF 700
Query: 297 TVPESHRKPLKR--SSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYS 354
+ K LK +T++S D+V+ E CI+ K K + + L E
Sbjct: 701 KILNDQNKALKSEVQKLQTLVSEQPNKDVVE-QMEKCIQE-KDEKLKTVEELLETGLIQV 758
Query: 355 ALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKD 388
A K EE L + E SL+ K VQ +A D
Sbjct: 759 ATK---EEELNAIRTENSSLT-KEVQDLKAKQND 788
Score = 47.0 bits (110), Expect = 4e-05
Identities = 78/382 (20%), Positives = 162/382 (42%), Gaps = 72/382 (18%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEI 63
E + + +K+D+ + LQ ++ E K L D+N L+ VQ++ T EQ
Sbjct: 669 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN-- 726
Query: 64 EYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ + +Q+E Q ++ K T EL ET VA + E + ++
Sbjct: 727 KDVVEQMEKCIQEKDEKLK-------TVEELLETGLIQVATKE----------EELNAIR 769
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITS 183
T L +V++LK+ ++ SFA L E +L++
Sbjct: 770 TENSSLTKEVQDLKA------------KQNDQVSFASLVE--ELKKVI------------ 803
Query: 184 LQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAY 243
E++ +K +L+A+L K T+++ + +E L++++G
Sbjct: 804 --------HEKDGKIKSVEELLEAELLKVANKEKTVQD----LKQEIKALKEEIGNVQLE 851
Query: 244 RARALELEAEVAEMRQMLQSEHPFVNGVEKLVPD-----SLYVPFKEPSQSLLEEMFLTV 298
+A+ L + ++V E++ +L+ + +N ++ ++ + + + + Q E + V
Sbjct: 852 KAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHV 911
Query: 299 PESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKA-VKQR------GISLLHEVDT 351
E + LK +SS + L +IV +E ++R +A +K+R LL +V
Sbjct: 912 QEVAQHNLKEASSASQFEEL---EIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQD 968
Query: 352 QYSALKVKYEELLKKCQEEQDS 373
+ K + E+L ++ ++ S
Sbjct: 969 ENKLFKSQIEQLKQQNYQQASS 990
Score = 41.6 bits (96), Expect = 0.001
Identities = 100/493 (20%), Positives = 187/493 (37%), Gaps = 90/493 (18%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQ-LAAELGKTLLDRNTEL----------------E 46
E L+E +K QDL+Q+++ L E+G L++ +L E
Sbjct: 814 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKE 873
Query: 47 DSVQQMYTTNQEQLQEIEYLTKQVELLRQMNE----------QH-------AKVYEQLDV 89
+ + M +E+ +++ K ++ L++ NE QH A +E+L++
Sbjct: 874 EQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEI 933
Query: 90 TARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKC 149
+E E ++L A K + + S T+ ++ +Q +SQ+E+LK + S
Sbjct: 934 VLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPP 993
Query: 150 DQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLK-KTVTMLQAQ 208
+E KE+ L ++ SL+ ++N L+ K ++A
Sbjct: 994 HEELLKVISEREKEISGL----------WNELDSLKDAVEHQRKKNNDLREKNWEAMEAL 1043
Query: 209 LSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHP-- 266
S E+ + V K + E +QQ+ A+ELEA+ + + P
Sbjct: 1044 ASTEKMLQ-------DKVNKTSKERQQQV--------EAVELEAKEVLKKLFPKVSVPSN 1088
Query: 267 -----FVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGS 321
+++G EK + + +LE E H L + E S LA
Sbjct: 1089 LSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMH--TLLQLECEKYKSVLA-- 1144
Query: 322 DIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSL--SHKAV 379
+ + Q+ L V+ + + KVK +E K ++ Q S S + +
Sbjct: 1145 ------------ETEGILQK---LQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQEL 1189
Query: 380 QTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQE 439
+ R+ KD+ + + E + EL E + T E K L E+ + + E
Sbjct: 1190 ERLRSENKDIENLRREREHLE--MELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSE 1247
Query: 440 IDEQRTKYRSLSS 452
Q + L +
Sbjct: 1248 AVRQNEELNLLKA 1260
Score = 35.4 bits (80), Expect = 0.11
Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 14/214 (6%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
Q LQ+ ++ K +D + + +Q +T+++++L+ + K +E LR+ E
Sbjct: 1151 QKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLE 1210
Query: 82 KVYEQLDVT-------ARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVE 134
E+ ++ REL++ +L S + + E + L+ ++ +++
Sbjct: 1211 MELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTKLR 1270
Query: 135 ELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEE 194
+ Q R D K S ++ + + V S + + S E
Sbjct: 1271 ----TEQNERQKVAGDLHKAQQSLELIQS--KIVKAAGDTTVIENSDVSPETESSEKETM 1324
Query: 195 NEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLK 228
+ L +TVT LQ L Q ++T E+E+ VL+
Sbjct: 1325 SVSLNQTVTQLQQLLQAVNQ-QLTKEKEHYQVLE 1357
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 51.6 bits (122), Expect = 1e-06
Identities = 76/377 (20%), Positives = 155/377 (41%), Gaps = 37/377 (9%)
Query: 27 DLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNE---QHAKV 83
+L+ L K + T ++ + + NQ I+ L ++ + R +N+ Q +
Sbjct: 193 ELKKERALRKDEASKITIWKEQYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSS 252
Query: 84 YEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNID-----------HLQSQ 132
A EE Q+L A+ + +++ L +T+E ++ I+ ++
Sbjct: 253 RTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKL 312
Query: 133 VEELKSSGQGRRSPGKCDQEKP---APSFACLKELYDLRQHFVYDHVFAEKITSLQGQPS 189
+E L+S G ++ + D E+ A + + L L + ++ + + + +
Sbjct: 313 LEMLQSKGLSAKATEE-DHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENA 371
Query: 190 PDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSEL-----EQQLGATGAYR 244
PD + + L+ + M +++S + +EEE + LK N L E+++ YR
Sbjct: 372 PDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQM-LKSNGALSTEEREEEMKQMEVYR 430
Query: 245 ARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRK 304
+ + ++ +V ++++ L S+ ++ + K+ + L E+ E RK
Sbjct: 431 SHSKFMKNKVEQLKEELSSK------------EAQWEELKKKAAGLQAEIGQVKQELSRK 478
Query: 305 PLKRSSSETILSSLAGS-DIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEEL 363
+ + +T L +L K H E A +QR L EVD L+ K L
Sbjct: 479 DTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETML 538
Query: 364 LKKCQEEQDSLSHKAVQ 380
KK ++ QD K Q
Sbjct: 539 NKKTKQIQDMAEEKGTQ 555
Score = 40.8 bits (94), Expect = 0.003
Identities = 87/420 (20%), Positives = 179/420 (42%), Gaps = 59/420 (14%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQ-------EQLQEIEYLTKQVELLR 74
+DL++++Q+ G L E E ++Y ++ EQL+E E +K+ +
Sbjct: 399 RDLEEEIQMLKSNG-ALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKE-ELSSKEAQW-E 455
Query: 75 QMNEQHAKVYEQLDVTARELEETNQKLVA----------DSKASQQKILSLTETIEC--- 121
++ ++ A + ++ +EL + +L+A S+Q I L E++
Sbjct: 456 ELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQ 515
Query: 122 ----LQTNIDHLQSQVEELKSS-GQGRRSPGKCDQEK--PAPSFACLKELYDLRQHFVYD 174
LQT +D L+ ++EE ++ + + +EK A LK++ D+++ V
Sbjct: 516 RAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKV-- 573
Query: 175 HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELE 234
+V +KI +LQ Q E++ LK+ V LQA + T+EE + L+
Sbjct: 574 NVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLK 633
Query: 235 QQLG--------ATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEP 286
+Q Y+ +L+ +V+ ++ L + + +++ K+
Sbjct: 634 EQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKD 693
Query: 287 SQSLLEEMFLTVPESHRKPLKRSSS-----ETILSSLAG---SDIVKGHEETCIR----- 333
S+ L+ + + + + + LK S E L + A SD ++ E R
Sbjct: 694 SR--LKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDES 751
Query: 334 -RAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQD---SLSHKAVQTSRAAAKDL 389
+A+A R + +L EV+ + + K EL ++ +++ +L HK + +A+ L
Sbjct: 752 SKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQML 811
Score = 37.0 bits (84), Expect = 0.037
Identities = 57/263 (21%), Positives = 108/263 (41%), Gaps = 44/263 (16%)
Query: 129 LQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELY--DLRQHFVYDHVFAEKITSLQG 186
LQ+Q++E+ R + + K + S +K + +L++ A KIT +
Sbjct: 154 LQTQLKEVLRENDLLRKDVEVKESKLSSSMNSIKTFWSPELKKERALRKDEASKITIWKE 213
Query: 187 QPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYG------LVLKENSELEQQLGAT 240
Q +EEN+H++ T+ LQ +L ++R +++ V + E Q+L A
Sbjct: 214 QYRVVQEENQHMQMTIQALQDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAE 273
Query: 241 GAYRARAL-ELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVP 299
+A+ L L + EM ++++ +N +
Sbjct: 274 HERQAKELFLLRKTLEEMELRIETQKQTLNARD--------------------------- 306
Query: 300 ESHRKPLKRSSSETILSSLAGSDIVKGHEET-CIRRAKAVKQRGISLLHEVDTQYSALKV 358
ES +K L+ S+ + + D HE T + A+ SLL + + + S L+
Sbjct: 307 ESIKKLLEMLQSKGLSAKATEED----HERTRRLAEAEMHVHHLESLLEQKEKENSMLR- 361
Query: 359 KYEELLKKCQEEQDSLSHKAVQT 381
EE+ ++ + DS KA+QT
Sbjct: 362 --EEMHRRFENAPDSAKTKALQT 382
Score = 31.6 bits (70), Expect = 1.6
Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 46/272 (16%)
Query: 32 AELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTA 91
AEL + + D+N ++ + + ++ Q +E ++ + L ++Q + D
Sbjct: 780 AELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRI 839
Query: 92 RELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQ 151
ELEE ++ V A ++ +L+ E+ +TN + QVEEL +
Sbjct: 840 EELEEALRESV-QITAEREMVLAQEES---ARTN---AEKQVEELLMA-----------M 881
Query: 152 EKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQ----- 206
EK +K Q + AEK T L + E +HL++ + M Q
Sbjct: 882 EKVKQELESMKAKLSSTQQSL-----AEKETHLTNLRA---ERRKHLEEVLEMKQEALLA 933
Query: 207 ---------AQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEM 257
A L L K+ T +EE + +E L QQL R ++L A+ E
Sbjct: 934 AISEKDANIALLELSSSKKKT-QEEVAALKREKDRLVQQLKQQTQNR---MKLMADNYED 989
Query: 258 RQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQS 289
S N K PD + P E Q+
Sbjct: 990 DHFKSSHSNQTN--HKPSPDQIIQPLLELDQN 1019
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 51.2 bits (121), Expect = 2e-06
Identities = 83/354 (23%), Positives = 148/354 (41%), Gaps = 36/354 (10%)
Query: 41 RNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQK 100
R TE Q + ++L+E+ T++ + ++E+ K+ E VT R LE QK
Sbjct: 658 RCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKE---VTVRGLEPEIQK 714
Query: 101 LVADSKASQQKILSLTETIECLQTNIDHLQ---SQVEELKSSGQGRRSPGKCDQEKPAPS 157
L+A K +++ SL E E LQ++ Q Q EEL+ + R QE+
Sbjct: 715 LIARHKQEVRRLKSLHEA-ELLQSDERASQRCLRQAEELREQLE-REKEALGQQERERAR 772
Query: 158 FACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQK-- 215
EL +LRQ + + + +E+E H + T+ Q QL LERQ
Sbjct: 773 QRQRAELEELRQQLEESSSALTRALRAEFEKGREEQERRHQMELNTLKQ-QLELERQAWE 831
Query: 216 --RVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEK 273
R EE + +L EL +++ + R E+E + L+++ +
Sbjct: 832 AGRTRKEEAW--LLNREQELREEI-----RKGRDKEIELVI----HRLEADMALAKEESE 880
Query: 274 LVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIR 333
+S ++ ++ L E+ +S RK +R S L G E ++
Sbjct: 881 KAAESRIKRLRDKYEAELSEL----EQSERKLQER------CSELKGQLGEAEGENLRLQ 930
Query: 334 RAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAK 387
K+R + V+ Q S+ + ++++ QE +D L+ +T +A A+
Sbjct: 931 GLVRQKERALEDAQAVNEQLSSERSNLAQVIR--QEFEDRLAASEEETRQAKAE 982
Score = 31.6 bits (70), Expect = 1.6
Identities = 64/265 (24%), Positives = 114/265 (43%), Gaps = 41/265 (15%)
Query: 20 DHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQ 79
D D QQ+ E G L+ +E+ SV ++ +E+ KQ LL Q
Sbjct: 542 DQLDSQQE-GWVPEAGPGPLELGSEVSTSVMRLKLEVEEK--------KQAMLLLQR--- 589
Query: 80 HAKVYEQLDVTARELEETNQKLVADSKAS--------QQKILSLTETIECLQTNIDHLQS 131
+ +Q D+TAR ++ET + L + Q+ + + + IE + + ++
Sbjct: 590 --ALAQQRDLTARRVKETEKALSRQLQRQREHYEATIQRHLAFIDQLIEDKKVLSEKCEA 647
Query: 132 QVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDL-----RQHFVYDHVFAEKITSLQG 186
V ELK Q Q + LKEL R+ ++ + K +++G
Sbjct: 648 VVAELKQEDQRCTERVAQAQAQHELEIKKLKELMSATEKARREKWISEKTKKIKEVTVRG 707
Query: 187 -QPSPDE---EENEHLKKTVTMLQAQL--SLER--QKRVTMEEEYGLVLKENSELEQQ-L 237
+P + + +++ ++ +A+L S ER Q+ + EE L+E E E++ L
Sbjct: 708 LEPEIQKLIARHKQEVRRLKSLHEAELLQSDERASQRCLRQAEE----LREQLEREKEAL 763
Query: 238 GATGAYRARALELEAEVAEMRQMLQ 262
G RAR + AE+ E+RQ L+
Sbjct: 764 GQQERERARQRQ-RAELEELRQQLE 787
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 50.4 bits (119), Expect = 3e-06
Identities = 88/379 (23%), Positives = 155/379 (40%), Gaps = 76/379 (20%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQ----------QMYTTNQEQLQEIEYLTKQVE 71
++L L+ + L + N EL +V+ Q+ N+E E E L K +E
Sbjct: 683 KNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLE 742
Query: 72 LLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQS 131
LL+ K E+L+V+ + L+ NQ+L + S +KI L ++ L+ LQ
Sbjct: 743 LLKAS----FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Query: 132 QVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPD 191
+EELK S K L L ++ SL+ + S
Sbjct: 799 NLEELKISS---------------------KRLEQLE----------KENKSLEQETSQL 827
Query: 192 EEENEHLKKTVTMLQAQLSLERQKRVTMEE---EYGLVLKENSELEQQLGATGAYRARAL 248
E++ + L+K L+ Q + K T+EE + G + KEN L +++G R
Sbjct: 828 EKDKKQLEKENKRLRQQAEI---KDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 249 ELEAEVAEM-RQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLK 307
ELE E E+ ++ V E LV + L +Q + ++ E + L
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKL------KTQQMNNDLEKLTHELEKIGLN 938
Query: 308 RSSSETILSSLAGSD----IVKGHEETCIRRAKAVKQRGISLLH---EVDTQYS------ 354
+ E +L +D +++ E+ ++++ +K+ I+ L E T Y+
Sbjct: 939 K---ERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 995
Query: 355 --ALKVKYEELLKKCQEEQ 371
+K YE L ++ EE+
Sbjct: 996 LKTVKKNYEALKQRQDEER 1014
Score = 49.3 bits (116), Expect = 7e-06
Identities = 102/486 (20%), Positives = 211/486 (43%), Gaps = 79/486 (16%)
Query: 21 HQDLQQDLQLAAELGKTLLDRNTE---LEDSVQQMYTTNQEQLQEIE---YLTKQVELLR 74
H+ +++LQL A+L ++R+ + +E+ +++ T Q Q ++ +L ++E +
Sbjct: 378 HELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437
Query: 75 QMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVE 134
+ +E + L EL T+ +L+ +Q SLT+T+E L+T +D ++
Sbjct: 438 RTSELSEAPQKSLGHEVNEL--TSSRLLKLEMENQ----SLTKTVEELRTTVDSVEGNAS 491
Query: 135 E-LKSSGQGRRSPGKCD-------QEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQG 186
+ LK + +R K + QEK + L+ +L + + + EK
Sbjct: 492 KILKMEKENQRLSKKVEILENEIVQEKQS-----LQNCQNLSKDLMKEKAQLEKTIETLR 546
Query: 187 QPSPD-----EEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKEN----------- 230
+ S E+ENEHL +TV+ L+ + + + RV E+ +L E+
Sbjct: 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 231 ----SELEQQLGATGAYRARALELEAEV--------------------AEMRQMLQSEHP 266
+++++L RA ELE E+ E + L+ E+
Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENS 666
Query: 267 FVNGVEKLVPDSLYVPFKEPSQSL--LEEMFLTVPESHRKPLKRSSSETILSSLAGSDIV 324
+ + + +L FK + L LE+ + E + + L+R+ +S+ + +
Sbjct: 667 ELERENRKLKKTL-DSFKNLTFQLESLEKENSQLDEENLE-LRRNVESLKCASMKMAQLQ 724
Query: 325 KGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSL--SHKAVQTS 382
++E + K ++G+ LL + L+V Y+ L + Q Q +L S+K +Q
Sbjct: 725 LENKE--LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 383 RAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDE 442
+ +DL N + +++S E + E K+L +E S ++K K+++++
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEK-----ENKSLEQET-SQLEKDKKQLEK 836
Query: 443 QRTKYR 448
+ + R
Sbjct: 837 ENKRLR 842
Score = 49.3 bits (116), Expect = 7e-06
Identities = 104/466 (22%), Positives = 199/466 (42%), Gaps = 59/466 (12%)
Query: 2 LAENLVEEFEMKEDEPWYDHQ---DLQQDLQLAAELG-KTLLDRNTELEDSVQQMYTTNQ 57
L EN + ++ E E + +Q L+Q Q++AE K + N L +S+++
Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE----TS 600
Query: 58 EQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSL-- 115
+L +IE+ +Q++ + + Y++ A ELE L +++ Q+KI +L
Sbjct: 601 SKLSKIEFEKRQIK-------KELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Query: 116 -TETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYD 174
E IE L+ L+ + +LK + ++ + + +E +LR++
Sbjct: 654 TCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL 713
Query: 175 HVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELE 234
+ K+ LQ + E E E LKK + +L+A +K +E Y + EN L+
Sbjct: 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASF----KKTERLEVSYQGLDIENQRLQ 769
Query: 235 QQLGATGAYRARALELEAEVAEM-RQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEE 293
+ L + + + LE E + EM Q LQ +E+L S + E LE+
Sbjct: 770 KTLENSNK-KIQQLESELQDLEMENQTLQ------KNLEELKISSKRLEQLEKENKSLEQ 822
Query: 294 MFLTVPESHRKPLK------RSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLH 347
+ E +K L+ R +E ++L +++ G+ + + + I +
Sbjct: 823 ETSQL-EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN----LEKENKTLSKEIGIYK 877
Query: 348 EVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTG-------VNAQSEPVA 400
E + L+ + +EL+K+ ++ K + T R +DL +N E +
Sbjct: 878 ESCVRLKELEKENKELVKRA-----TIDIKTLVTLR---EDLVSEKLKTQQMNNDLEKLT 929
Query: 401 SGWELASVNPEPV--SSPTTPPEYKALFKEIFSCIKKTKQEIDEQR 444
E +N E + +T YK L ++ S +KK+ EI E++
Sbjct: 930 HELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKS-LEIKEEK 974
Score = 42.7 bits (99), Expect = 7e-04
Identities = 61/253 (24%), Positives = 104/253 (41%), Gaps = 30/253 (11%)
Query: 2 LAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTN----- 56
+ E + E + +E +Q L+Q+L+ + + L R E E VQ +
Sbjct: 970 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE-ERMVQSSPPISGEDNK 1028
Query: 57 --QEQLQEIEYLTKQVELLRQMNEQHAKVYEQ---LDVTARELEETNQKLVADSKASQQK 111
+E + L K + L ++ +A + + L ++LE N L A A Q++
Sbjct: 1029 WERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Query: 112 ILSLTETIECLQTNIDHLQSQVEELKSSGQG----------RRSPGKCDQEKPAPSFACL 161
+SL E LQT LQ + L S ++S + + E L
Sbjct: 1089 TVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDL 1148
Query: 162 KELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEE 221
K LYD + DH EK+ L + + + E + K T+ A +LE + R +E+
Sbjct: 1149 KSLYD---SLIKDH---EKLELLHERQASEYE--SLISKHGTLKSAHKNLEVEHR-DLED 1199
Query: 222 EYGLVLKENSELE 234
Y +LK+ +LE
Sbjct: 1200 RYNQLLKQKGQLE 1212
Score = 35.8 bits (81), Expect = 0.082
Identities = 64/338 (18%), Positives = 139/338 (41%), Gaps = 64/338 (18%)
Query: 61 QEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIE 120
QE+E T+Q+ +Q EQ+++ + L++ N L++D+++++ L + +
Sbjct: 265 QELEEKTEQLLDCKQE-------LEQMEIELKRLQQENMNLLSDARSARMYRDEL-DALR 316
Query: 121 CLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEK 180
+D L+S+V K + L+D+ + +
Sbjct: 317 EKAVRVDKLESEVSRYK------------------------ERLHDIE-------FYKAR 345
Query: 181 ITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT 240
+ L+ E+N+ L +T TML+ QL R + + E + KEN +L+ +L
Sbjct: 346 VEELK-------EDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKL--- 391
Query: 241 GAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPE 300
+E + + ++ ++++ ++ + +SL++ ++ S E+ +
Sbjct: 392 ---HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQK 448
Query: 301 SHRKPLKRSSSETILS-SLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVK 359
S + +S +L + + K EE +R + S + +++ + L K
Sbjct: 449 SLGHEVNELTSSRLLKLEMENQSLTKTVEE--LRTTVDSVEGNASKILKMEKENQRLSKK 506
Query: 360 YEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSE 397
E L + +E+ SL Q + +KDL AQ E
Sbjct: 507 VEILENEIVQEKQSL-----QNCQNLSKDLMKEKAQLE 539
Score = 35.8 bits (81), Expect = 0.082
Identities = 41/233 (17%), Positives = 96/233 (41%), Gaps = 35/233 (15%)
Query: 4 ENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEI 63
E L+ + + +D L+ L+ + E+ + ++ LE +++ NQ+ QE+
Sbjct: 940 ERLLHDEQSTDDRYKLLESKLESTLKKSLEIKE---EKIAALEARLEESTNYNQQLRQEL 996
Query: 64 EYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQ 123
+ + K E L+Q ++ V ++ + K +S+ + +++L + + + ++
Sbjct: 997 KTVKKNYEALKQRQDEERMVQSSPPISGED-----NKWERESQETTRELLKVKDRLIEVE 1051
Query: 124 TNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITS 183
N LQ++ + LK+ L+Q ++ +I +
Sbjct: 1052 RNNATLQAEKQALKTQ---------------------------LKQLETQNNNLQAQILA 1084
Query: 184 LQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQ 236
LQ Q +E+N L+ LQ + S + ++ + +L + S LE +
Sbjct: 1085 LQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1137
Score = 35.4 bits (80), Expect = 0.11
Identities = 89/433 (20%), Positives = 164/433 (37%), Gaps = 66/433 (15%)
Query: 38 LLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQL---------- 87
LL + + LE+ + + ++ + L K E L ++E+ A YE L
Sbjct: 1127 LLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSA 1186
Query: 88 ----DVTARELEET-NQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQG 142
+V R+LE+ NQ L + + + E + L N +H E K G+
Sbjct: 1187 HKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGEN 1246
Query: 143 RRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKI--------TSLQGQPSPDEEE 194
R Q LKE L+ DH + + T L+ + S +E+
Sbjct: 1247 DRLNHTYSQ--------LLKETEVLQT----DHKNLKSLLNNSKLEQTRLEAEFSKLKEQ 1294
Query: 195 NEHLKKTVTMLQAQLSLERQKRVTMEEE--------YGLVLKENSELEQQLGATGAYRAR 246
+ L T T L Q L Q + +EEE L+L+ + LEQ + + +
Sbjct: 1295 YQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVE 1354
Query: 247 ALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPE----SH 302
+ ++ E+R+ + +E+ + D F +PS ++T+
Sbjct: 1355 QRQYIDKLNELRRQKEK-------LEEKIMDQ--YKFYDPSPPRRRGNWITLKMRKLIKS 1405
Query: 303 RKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDT----QYSALKV 358
+K + R +++ + SD +G + + ++ G + L + T + S + +
Sbjct: 1406 KKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQDSSSVGSNSLEDGQTLGTKKSSMVAL 1465
Query: 359 KYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTT 418
K L+ +++D + KA + DL QS +A W ++ N E +T
Sbjct: 1466 KRLPFLRNRPKDKDKM--KACYRRSMSMNDL----VQSMVLAGQWTGSTENLEVPDDIST 1519
Query: 419 PPEYKALFKEIFS 431
K L FS
Sbjct: 1520 GKRRKELGAMAFS 1532
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 50.4 bits (119), Expect = 3e-06
Identities = 82/404 (20%), Positives = 163/404 (40%), Gaps = 56/404 (13%)
Query: 8 EEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLT 67
EE + K+ + DL LQ E + ++ L S Q+ +E + +E
Sbjct: 883 EELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVE--- 939
Query: 68 KQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSK---ASQQKILSLTETIECLQT 124
++ E+ ++ + K+ ++ +E+++ LV K ++ K+ +LTE +E L
Sbjct: 940 EEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNE 999
Query: 125 NIDHLQSQVEELKSSGQGRRSPGKCDQEK-PAPSFACLKELYDLRQHFVYDHVFAEKITS 183
+I L + ++ + Q ++EK + S A LK +++
Sbjct: 1000 DISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLK--------------LEQQVDE 1045
Query: 184 LQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKE-----------NSE 232
L+G + + + ++ + L+ L L R+ +E + +E NS+
Sbjct: 1046 LEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSK 1105
Query: 233 LEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPD------SLYVPFKEP 286
+E + G + EL+ ++ ++++ L++E +E+ D L +E
Sbjct: 1106 VENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEV 1165
Query: 287 SQSLLEEMFLT-VPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISL 345
S L ++ +T E+ + L R E L H ET + ++K+R
Sbjct: 1166 GGSSLAQLEITKKQETKFQKLHRDMEEATL-----------HFET---TSASLKKRHADS 1211
Query: 346 LHEVDTQYSAL---KVKYEELLKKCQEEQDSLSHKAVQTSRAAA 386
L E++ Q L K K E+ Q E D L + Q +RA A
Sbjct: 1212 LAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKA 1255
Score = 41.2 bits (95), Expect = 0.002
Identities = 76/409 (18%), Positives = 171/409 (41%), Gaps = 54/409 (13%)
Query: 5 NLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIE 64
N+++ E ED ++L LQ AAE RN LE + Q+ + L ++
Sbjct: 1390 NVIQRTEDLEDAK----KELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLG 1445
Query: 65 YLT--------KQVE---LLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKIL 113
+ KQ++ L ++H + LD + +E++ + +L+ ++ I+
Sbjct: 1446 KVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIV 1505
Query: 114 ---SLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQ- 169
+L + LQ I +L +QV E + K +E+ L+E +
Sbjct: 1506 GQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALER 1565
Query: 170 ------HFVYDHVFAEKITSLQGQPSPDEEENEHLKK----TVTMLQAQLSLERQKRVTM 219
HF + + A+ L+ + S +EE E+ ++ T+ LQ+ L E + R+ +
Sbjct: 1566 NESKILHFQLELLEAK--AELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEV 1623
Query: 220 EEEYGLVLKENSELEQQLGATGAYRARAL----ELEAEVAEMRQMLQSEHPFVNGVEKLV 275
+ ++ +E+E QL + A +L+ ++ +++ L + +++ V
Sbjct: 1624 TRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQV 1683
Query: 276 PDSLYVPFKEPS--QSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIR 333
V + S QS LE++ ++ R +R S E +L + ++ + +
Sbjct: 1684 A----VAERRNSLLQSELEDLRSLQEQTERG--RRLSEEELLEATERINLFYTQNTSLLS 1737
Query: 334 RAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTS 382
+ K +++ + ++ + EE++++CQ ++ A++ +
Sbjct: 1738 QKK-----------KLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAA 1775
Score = 35.4 bits (80), Expect = 0.11
Identities = 65/318 (20%), Positives = 128/318 (40%), Gaps = 34/318 (10%)
Query: 57 QEQLQEIEY-LTKQVELLRQMNEQHAKVYEQLDVTARELEETN---QKLVADSKASQQKI 112
Q Q+++++ L +L + EQ A + + ELE+ ++ + S++++
Sbjct: 1659 QIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEEL 1718
Query: 113 LSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFV 172
L TE I T L SQ ++L++ + +E C ++ +
Sbjct: 1719 LEATERINLFYTQNTSLLSQKKKLEAD------VARMQKEAEEVVQECQNAEEKAKKAAI 1772
Query: 173 YDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSE 232
+E++ Q + E E++++T+T LQ +L+ E ++ M K+ +
Sbjct: 1773 EAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLA-EAEQMALMGSR-----KQIQK 1826
Query: 233 LEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLE 292
LE R R LE E E E+R+ +++ +E+ + + Y E + L
Sbjct: 1827 LES--------RVRELEGELE-GEIRRSAEAQRG-ARRLERCIKELTYQA--EEDKKNLS 1874
Query: 293 EMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQ 352
M + + K + + A + K ++ VK+R ++Q
Sbjct: 1875 RMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQ--HELNEVKERA----EVAESQ 1928
Query: 353 YSALKVKYEELLKKCQEE 370
+ LK+K E KK QEE
Sbjct: 1929 VNKLKIKAREFGKKVQEE 1946
Score = 30.4 bits (67), Expect = 3.5
Identities = 41/245 (16%), Positives = 96/245 (39%), Gaps = 20/245 (8%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHA 81
+ +++ ++ AEL +TL N E+ + ++ +++E K++ + Q +
Sbjct: 1357 EQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAM 1416
Query: 82 KVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQ 141
V + + Q + D+ + K+ S ++ Q + ++ Q
Sbjct: 1417 GVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQ 1476
Query: 142 GRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKT 201
+ + + + LK Y+ S+ GQ + EN++L++
Sbjct: 1477 ALLDASQKEVQALSTELLKLKNTYE---------------ESIVGQETL-RRENKNLQEE 1520
Query: 202 VTMLQAQLSLERQKRVTMEEEYGLVLKENSE----LEQQLGATGAYRARALELEAEVAEM 257
++ L Q+ + ME+ L+ +E +E LE+ GA ++ L + E+ E
Sbjct: 1521 ISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEA 1580
Query: 258 RQMLQ 262
+ L+
Sbjct: 1581 KAELE 1585
Score = 29.6 bits (65), Expect = 5.9
Identities = 63/295 (21%), Positives = 114/295 (38%), Gaps = 49/295 (16%)
Query: 179 EKITSLQGQPSPDEEENEHLK-KTVTMLQA------QLSLERQKRVTMEEEYGLVLK--- 228
E+ LQ E + E LK K V++ Q QL E++ +EE+ ++K
Sbjct: 866 EECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKI 925
Query: 229 ----------ENSELEQQLGATGAYRARALE-----LEAEVAEMRQMLQSEHPFVNGVEK 273
E E E+++ + R R LE L+ E+ ++ ML E
Sbjct: 926 QLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEH 985
Query: 274 LVPD-SLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCI 332
V + + V F S L V E+H++ L D + EE
Sbjct: 986 KVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTL---------------DDLHMEEEKLS 1030
Query: 333 RRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGV 392
+KA + L +VD AL+ + + + C+ E L ++ +R + ++L
Sbjct: 1031 SLSKA----NLKLEQQVDELEGALEQERKARMN-CERELHKLEGN-LKLNRESMENLESS 1084
Query: 393 NAQ--SEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRT 445
E EL+ +N + + + + KE+ + IK K++++ +RT
Sbjct: 1085 QRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERT 1139
>gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 1 [Homo sapiens]
Length = 953
Score = 50.4 bits (119), Expect = 3e-06
Identities = 67/302 (22%), Positives = 132/302 (43%), Gaps = 38/302 (12%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQE-IEYLTKQVELLRQMNEQH 80
++ ++DL+LAA +G++LL +N L T E L+E +E++ ++V Q+ +
Sbjct: 120 EEKERDLELAARIGQSLLKKNKTL--------TERNELLEEQVEHIREEVS---QLRHEL 168
Query: 81 AKVYEQLDVTARELEETNQKLVADSKASQQKILSLTET---IECLQTNIDHLQSQVEELK 137
+ E L EE+ + V + + + S + ++ LQ + L+ + L+
Sbjct: 169 SMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLR 228
Query: 138 SSGQGRRSPGKCDQEKPAPSF-ACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENE 196
S ++ +EK C+KEL D +I S+ + + E+
Sbjct: 229 SEASQLKTETITYEEKEQQLVNDCVKELRDAN----------VQIASISEELAKKTEDAA 278
Query: 197 HLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT-GAYR---ARALELEA 252
++ +T L +Q+ V ++++ EN EL Q LGA A R A ELE
Sbjct: 279 RQQEEITHLLSQI-------VDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELED 331
Query: 253 EVAEMRQML-QSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSS 311
+ AE +ML +++ N K +P++ + ++ + + + RK L+ +
Sbjct: 332 KYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEA 391
Query: 312 ET 313
E+
Sbjct: 392 ES 393
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 50.4 bits (119), Expect = 3e-06
Identities = 67/302 (22%), Positives = 132/302 (43%), Gaps = 38/302 (12%)
Query: 22 QDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQE-IEYLTKQVELLRQMNEQH 80
++ ++DL+LAA +G++LL +N L T E L+E +E++ ++V Q+ +
Sbjct: 62 EEKERDLELAARIGQSLLKKNKTL--------TERNELLEEQVEHIREEVS---QLRHEL 110
Query: 81 AKVYEQLDVTARELEETNQKLVADSKASQQKILSLTET---IECLQTNIDHLQSQVEELK 137
+ E L EE+ + V + + + S + ++ LQ + L+ + L+
Sbjct: 111 SMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLR 170
Query: 138 SSGQGRRSPGKCDQEKPAPSF-ACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENE 196
S ++ +EK C+KEL D +I S+ + + E+
Sbjct: 171 SEASQLKTETITYEEKEQQLVNDCVKELRDAN----------VQIASISEELAKKTEDAA 220
Query: 197 HLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGAT-GAYR---ARALELEA 252
++ +T L +Q+ V ++++ EN EL Q LGA A R A ELE
Sbjct: 221 RQQEEITHLLSQI-------VDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELED 273
Query: 253 EVAEMRQML-QSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSS 311
+ AE +ML +++ N K +P++ + ++ + + + RK L+ +
Sbjct: 274 KYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEA 333
Query: 312 ET 313
E+
Sbjct: 334 ES 335
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/247 (21%), Positives = 105/247 (42%), Gaps = 18/247 (7%)
Query: 26 QDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMN------EQ 79
++LQ E ++L++ N +L + + + L+ I LT+Q +MN Q
Sbjct: 383 ENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERI-ILTEQAN--EKMNAKLEELRQ 439
Query: 80 HAKVYEQLDVTARELEETNQKLVADSKASQQKILSLT--ETIECLQTNIDHLQSQVEELK 137
HA L LE+ K + + Q++++ ET+ C+ ID Q +++
Sbjct: 440 HAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVE 499
Query: 138 SSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEH 197
+S + RS + KEL +L + A K+T Q P + + +
Sbjct: 500 TSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQD 559
Query: 198 LKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEM 257
K + + ++L+++K EE L L+ + Q + R R ELE ++A++
Sbjct: 560 NIKELEL--EVINLQKEK-----EELVLELQTAKKDANQAKLSERRRKRLQELEGQIADL 612
Query: 258 RQMLQSE 264
++ L +
Sbjct: 613 KKKLNEQ 619
Score = 33.5 bits (75), Expect = 0.41
Identities = 72/300 (24%), Positives = 115/300 (38%), Gaps = 47/300 (15%)
Query: 36 KTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELE 95
K L E+ S ++ + L++ + L + V L++ E +L L
Sbjct: 744 KNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLT 803
Query: 96 ETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQ--EK 153
E + V++S+ S +T+ IE L+T ++ +Q+ +L+ S + Q E
Sbjct: 804 EVRGQ-VSESEDS------ITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWEN 856
Query: 154 PAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPD--------EEENEHLKKTVTML 205
A L L V + K+ S Q EE H + T L
Sbjct: 857 IATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETEL 916
Query: 206 QAQL-SLERQ---------KRVTMEEEYGLVLKEN-SELEQQLGATGAYRARALELEAEV 254
QA+L +E+Q ++ + L+E+ SE EQQL +T + LE EV
Sbjct: 917 QAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREV 976
Query: 255 AEMRQMLQSEHPFVNGVEKLV----------------PDSL--YVPFKEPSQSLLEEMFL 296
E Q L E+ + L+ PDS YVP K P S ++E FL
Sbjct: 977 CEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPK-PKPSRVKEKFL 1035
Score = 32.0 bits (71), Expect = 1.2
Identities = 78/406 (19%), Positives = 167/406 (41%), Gaps = 47/406 (11%)
Query: 19 YDHQDLQQDLQLAA-----ELGKTLLDRNTELEDSVQ-QMYTTNQEQLQEIEYLTKQVEL 72
Y +QD ++L+L E + +L+ T +D+ Q ++ +++LQE+E + +L
Sbjct: 555 YQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELE--GQIADL 612
Query: 73 LRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQ 132
+++NEQ +K+ + + T R + + NQ++ Q + + E E + +
Sbjct: 613 KKKLNEQ-SKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671
Query: 133 VEELKSSGQGR-----------RSPGKCDQEKPAPSFACLKELYDL--RQHFVYDHVFAE 179
V +LK + R + + K + A K L D +Q V D
Sbjct: 672 VIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVAD---KR 728
Query: 180 KITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTME--EEYGLVLKENSELEQQL 237
K T +G L + + +S E KR + E+ ++ ++ ++L+++
Sbjct: 729 KETQSRGMEGTAARVKNWLGNEI---EVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKK 785
Query: 238 GATGAYRARALELEAEVAEMR-QMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFL 296
+ + + E+R Q+ +SE +E L + + F+ + L++ L
Sbjct: 786 ESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETE---MEFRSAQIADLQQKLL 842
Query: 297 TVPESHRKPLKRSSSETILSS----------LAGSDIVKGHEETCIRRAKAVKQRGISLL 346
R + + TIL + L S I E+ ++++K +L
Sbjct: 843 DAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKML 902
Query: 347 HEVDTQYSALKVKYE-ELLKKCQEEQDSLSH--KAVQTSRAAAKDL 389
E ++ ++ + + EL++ Q+ Q+ + + +Q S+ A K L
Sbjct: 903 FEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQL 948
Score = 29.6 bits (65), Expect = 5.9
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 22/112 (19%)
Query: 24 LQQDLQLAAELGKTLLDRN-------TELEDSVQQMYTTNQE-------QLQEIEYLTKQ 69
L+Q A++ K L + TEL+ + +M +QE QLQ+ + KQ
Sbjct: 888 LKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQ 947
Query: 70 VELLRQMNEQHAKVYEQLDVTARELE------ETNQKLVADSKASQQKILSL 115
+E ++E+ ++ L ELE E NQ+L+ +++ +QK+ L
Sbjct: 948 LE--ESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLL 997
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 50.1 bits (118), Expect = 4e-06
Identities = 56/251 (22%), Positives = 107/251 (42%), Gaps = 25/251 (9%)
Query: 21 HQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQH 80
HQ+L+ +LQL + + + E + QQ +Q QE + L +Q +L +Q+ EQ
Sbjct: 143 HQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQ 202
Query: 81 AKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQV-EELKSS 139
+Q + ++L + ++L QQ+ L + + LQ Q Q+ ++L
Sbjct: 203 LLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQ-----QGQLQQQLLQQ 257
Query: 140 GQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQP------SPDEE 193
Q + +Q++ L + + Q + ++ LQ Q P+EE
Sbjct: 258 QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEE 317
Query: 194 ENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAE 253
E L+ L ++ LE+Q++ L+ ELE+Q R L+L+ E
Sbjct: 318 EEVELELMPVDLGSEQELEQQRQ---------ELERQQELERQ----QEQRQLQLKLQEE 364
Query: 254 VAEMRQMLQSE 264
+ ++ Q L+ +
Sbjct: 365 LQQLEQQLEQQ 375
Score = 44.3 bits (103), Expect = 2e-04
Identities = 78/420 (18%), Positives = 158/420 (37%), Gaps = 78/420 (18%)
Query: 11 EMKEDEPWYDHQDLQQDLQLAAELGKTLL-------DRNTELEDSVQQMYTTNQEQLQEI 63
E +E+E + Q ++A +G + + R +L+ QQ Q Q +++
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQL 109
Query: 64 EYLTKQVELLRQ------------MNEQHAKVYEQLDVTARELEETNQKLVADSKASQQK 111
+ +EL +Q E+H V+ Q +L Q+L QQ+
Sbjct: 110 QQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQR 169
Query: 112 ILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHF 171
+ E ++ Q + Q E+L+ Q ++L +Q
Sbjct: 170 LQQQQEQLQTQQAQEQQVLQQQEQLQQQVQE-------------------QQLLQQQQEQ 210
Query: 172 VYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENS 231
+ ++ LQ Q ++E ++ + +LQ Q L++Q L+ ++ +
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQ----------LLQQQQA 260
Query: 232 ELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLL 291
+L+QQL LE + A+++Q L + ++ + + Q L
Sbjct: 261 QLQQQL------------LEQQQAQLQQQLLLQQ------QEQLQQQQQQQLLQQQQEQL 302
Query: 292 EEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDT 351
++ L P PL+ E + L D+ +E +R + +Q+ + E
Sbjct: 303 QQQQLQPP-----PLEPEEEEEVELELMPVDL-GSEQELEQQRQELERQQELERQQEQRQ 356
Query: 352 QYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPE 411
L+ + ++L ++ +++Q L + VQ +LT V ++ EL V PE
Sbjct: 357 LQLKLQEELQQLEQQLEQQQQQLEQQEVQL------ELTPVELGAQQQEVQLELTPVQPE 410
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,586,646
Number of Sequences: 37866
Number of extensions: 759178
Number of successful extensions: 6223
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 577
Number of HSP's that attempted gapping in prelim test: 4009
Number of HSP's gapped (non-prelim): 2081
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.