Search of human proteins with 55749865

Search of human proteins with 55749865

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
         (631 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...  1262   0.0  
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   761   0.0  
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         334   1e-91
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          334   1e-91
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    330   3e-90
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   311   1e-84
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            278   8e-75
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            278   8e-75
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   260   2e-69
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   251   1e-66
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   245   1e-64
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   245   1e-64
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   244   1e-64
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   244   1e-64
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   244   1e-64
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  224   2e-58
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   204   2e-52
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   196   5e-50
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   196   5e-50
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   195   9e-50
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   188   1e-47
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   187   2e-47
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      185   1e-46
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   185   1e-46
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   184   2e-46
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   181   2e-45
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   180   3e-45
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   177   3e-44
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   174   2e-43
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   173   5e-43

>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score = 1262 bits (3265), Expect = 0.0
 Identities = 631/631 (100%), Positives = 631/631 (100%)

Query: 1   MSHWAPEWKRAEANPRDLGASWDVRGSRGSGWSGPFGHQGPRAAGSREPPLCFKIKNNMV 60
           MSHWAPEWKRAEANPRDLGASWDVRGSRGSGWSGPFGHQGPRAAGSREPPLCFKIKNNMV
Sbjct: 1   MSHWAPEWKRAEANPRDLGASWDVRGSRGSGWSGPFGHQGPRAAGSREPPLCFKIKNNMV 60

Query: 61  GVVIGYSGSKIKDLQHSTNTKIQIINGESEAKVRIFGNREMKAKAKAAIETLIRKQESYN 120
           GVVIGYSGSKIKDLQHSTNTKIQIINGESEAKVRIFGNREMKAKAKAAIETLIRKQESYN
Sbjct: 61  GVVIGYSGSKIKDLQHSTNTKIQIINGESEAKVRIFGNREMKAKAKAAIETLIRKQESYN 120

Query: 121 SESSVDNAASQTPIGRNLGRNDIVGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYI 180
           SESSVDNAASQTPIGRNLGRNDIVGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYI
Sbjct: 121 SESSVDNAASQTPIGRNLGRNDIVGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYI 180

Query: 181 ESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRV 240
           ESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRV
Sbjct: 181 ESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRV 240

Query: 241 GIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGML 300
           GIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGML
Sbjct: 241 GIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGML 300

Query: 301 VLTPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQ 360
           VLTPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQ
Sbjct: 301 VLTPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQ 360

Query: 361 MNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALS 420
           MNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALS
Sbjct: 361 MNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALS 420

Query: 421 YLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIA 480
           YLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIA
Sbjct: 421 YLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIA 480

Query: 481 DDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVY 540
           DDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVY
Sbjct: 481 DDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVY 540

Query: 541 NYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVM 600
           NYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVM
Sbjct: 541 NYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVM 600

Query: 601 AEQYKLNQQKRHRETRSRKPGQRRKEFYFLS 631
           AEQYKLNQQKRHRETRSRKPGQRRKEFYFLS
Sbjct: 601 AEQYKLNQQKRHRETRSRKPGQRRKEFYFLS 631


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  761 bits (1964), Expect = 0.0
 Identities = 387/626 (61%), Positives = 485/626 (77%), Gaps = 5/626 (0%)

Query: 5   APEWKRAEANPRDLGASWDVRGSRGSGWSGPFGHQGPRAAGSREPPLCFKIKNNMVGVVI 64
           APE + AE   R     + V   RG  W G        AAG  E PLCF +K++ VG VI
Sbjct: 26  APERRPAEELNRTGPEGYSV--GRGGRWRGTSRPPEAVAAGHEELPLCFALKSHFVGAVI 83

Query: 65  GYSGSKIKDLQHSTNTKIQIINGESEAKVRIFGNREMKAKAKAAIETLIRK-QESYNSES 123
           G  GSKIK++Q +TNT IQII  + E+ V+IFG++ M+ KAKA I+  ++K +E+YNSE 
Sbjct: 84  GRGGSKIKNIQSTTNTTIQIIQEQPESLVKIFGSKAMQTKAKAVIDNFVKKLEENYNSEC 143

Query: 124 SVDNAASQTPIGRNLGR-NDIVGEAEPLSNWDRIRAAVVECEKRKWADLPPVKKNFYIES 182
            +D A  Q  +G++    N++V    PL +WD+IR   ++ +K KWADLPP+KKNFY ES
Sbjct: 144 GIDTAF-QPSVGKDGSTDNNVVAGDRPLIDWDQIREEGLKWQKTKWADLPPIKKNFYKES 202

Query: 183 KATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGI 242
            ATS MS+++  +WRKENFNIT DDLK GEKR IP PTC F DAFQ YP+++++I + G 
Sbjct: 203 TATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAGF 262

Query: 243 VKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGMLVL 302
            KPTPIQSQAWPI+LQGIDLI VAQTGTGKTL YLMPGFIHL  QP  + QRN PGMLVL
Sbjct: 263 QKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVL 322

Query: 303 TPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMN 362
           TPTRELAL VE EC KYSYKGL+S+C+YGG NR+ QIE++ KGVDIIIATPGRLNDLQM+
Sbjct: 323 TPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRLNDLQMS 382

Query: 363 NSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYL 422
           N VNL++ITYLV+DEADKMLDM FEPQI KILLDVRPDRQTVMTSATWP +V +LA SYL
Sbjct: 383 NFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYL 442

Query: 423 KDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADD 482
           K+PMIVYVG L+LVAV++VKQNIIVTTE+EK +  Q F+++MS  DKVI+FVS+K +AD 
Sbjct: 443 KEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADH 502

Query: 483 LSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNY 542
           LSSD  +  IS ESLHG+ EQ D+E+A+E+FK+G ++ILI TD+ SRGLD++DVTHVYN+
Sbjct: 503 LSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNF 562

Query: 543 DFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAE 602
           DFPRNI+ YVHR+G  GR G+TG S+T +T+ D ++A ELI IL+RANQS+PE+LV MAE
Sbjct: 563 DFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVASELINILERANQSIPEELVSMAE 622

Query: 603 QYKLNQQKRHRETRSRKPGQRRKEFY 628
           ++K +QQKR  E +  +P  R K+F+
Sbjct: 623 RFKAHQQKREMERKMERPQGRPKKFH 648


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  334 bits (857), Expect = 1e-91
 Identities = 194/444 (43%), Positives = 272/444 (61%), Gaps = 15/444 (3%)

Query: 165 KRKW--ADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCR 222
           K+KW  ++LP  +KNFY+E    + ++  +V   R++   IT   ++ G+  + PKP   
Sbjct: 119 KKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKK-EIT---VRGGD--VCPKPVFA 172

Query: 223 FKDA-FQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF 281
           F  A F QY  ++  ++     +PTPIQ Q +P+ L G D++ +AQTG+GKTL+YL+P  
Sbjct: 173 FHHANFPQY--VMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230

Query: 282 IHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSY-KGLKSICIYGGRNRNGQIE 340
           +H++ QP   E+ +GP  LVL PTRELA  V+     Y     LKS CIYGG  +  QI 
Sbjct: 231 VHINHQPYL-ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIR 289

Query: 341 DISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPD 400
           D+ +GV+I IATPGRL D   +   NLR  TYLV+DEAD+MLDM FEPQIRKI+  +RPD
Sbjct: 290 DLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPD 349

Query: 401 RQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQE 459
           RQT+M SATWP  VRQLA  +L+D   + VGNL L A + + Q + V  E EK   L Q 
Sbjct: 350 RQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQL 409

Query: 460 FVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518
             E M+  + K I+FV  K   DDL+      G  A  +HG+  Q +++  + +F+SG  
Sbjct: 410 MEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKA 469

Query: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578
            ILI TD+ SRGLD+ DV  V NYD+P + + YVHR+G   R+   GT+ T  T  + K 
Sbjct: 470 PILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQ 529

Query: 579 AGELIKILDRANQSVPEDLVVMAE 602
           A ELIK+L+ ANQ++   L+ + +
Sbjct: 530 ARELIKVLEEANQAINPKLMQLVD 553


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  334 bits (857), Expect = 1e-91
 Identities = 194/444 (43%), Positives = 272/444 (61%), Gaps = 15/444 (3%)

Query: 165 KRKW--ADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCR 222
           K+KW  ++LP  +KNFY+E    + ++  +V   R++   IT   ++ G+  + PKP   
Sbjct: 119 KKKWDLSELPKFEKNFYVEHPEVARLTPYEVDELRRKK-EIT---VRGGD--VCPKPVFA 172

Query: 223 FKDA-FQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF 281
           F  A F QY  ++  ++     +PTPIQ Q +P+ L G D++ +AQTG+GKTL+YL+P  
Sbjct: 173 FHHANFPQY--VMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAI 230

Query: 282 IHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSY-KGLKSICIYGGRNRNGQIE 340
           +H++ QP   E+ +GP  LVL PTRELA  V+     Y     LKS CIYGG  +  QI 
Sbjct: 231 VHINHQPYL-ERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIR 289

Query: 341 DISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPD 400
           D+ +GV+I IATPGRL D   +   NLR  TYLV+DEAD+MLDM FEPQIRKI+  +RPD
Sbjct: 290 DLERGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPD 349

Query: 401 RQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQE 459
           RQT+M SATWP  VRQLA  +L+D   + VGNL L A + + Q + V  E EK   L Q 
Sbjct: 350 RQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQL 409

Query: 460 FVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518
             E M+  + K I+FV  K   DDL+      G  A  +HG+  Q +++  + +F+SG  
Sbjct: 410 MEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKA 469

Query: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578
            ILI TD+ SRGLD+ DV  V NYD+P + + YVHR+G   R+   GT+ T  T  + K 
Sbjct: 470 PILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQ 529

Query: 579 AGELIKILDRANQSVPEDLVVMAE 602
           A ELIK+L+ ANQ++   L+ + +
Sbjct: 530 ARELIKVLEEANQAINPKLMQLVD 553


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  330 bits (845), Expect = 3e-90
 Identities = 191/444 (43%), Positives = 265/444 (59%), Gaps = 16/444 (3%)

Query: 165 KRKWA--DLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCR 222
           K+KW   +LP  +KNFY E    +  +  +V  +R+    IT            PKP   
Sbjct: 43  KKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSK-EITV------RGHNCPKPVLN 95

Query: 223 FKDAFQQYP-DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF 281
           F +A   +P +++  I R    +PT IQ+Q WP+ L G+D++ VAQTG+GKTLSYL+P  
Sbjct: 96  FYEA--NFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI 153

Query: 282 IHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIE 340
           +H++ QP   E+ +GP  LVL PTRELA  V+   ++Y     LKS CIYGG  +  QI 
Sbjct: 154 VHINHQPFL-ERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIR 212

Query: 341 DISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPD 400
           D+ +GV+I IATPGRL D       NLR  TYLV+DEAD+MLDM FEPQIRKI+  +RPD
Sbjct: 213 DLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPD 272

Query: 401 RQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQE 459
           RQT+M SATWP  VRQLA  +LKD + + +G L L A + + Q + V  + EK   L + 
Sbjct: 273 RQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRL 332

Query: 460 FVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518
             E MS  + K I+FV  K   D+L+      G  A  +HG+  Q +++  + +FK G  
Sbjct: 333 MEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKA 392

Query: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578
            ILI TD+ SRGLD+ DV  V NYD+P + + Y+HR+G   R+ KTGT+ T  T  + K 
Sbjct: 393 PILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQ 452

Query: 579 AGELIKILDRANQSVPEDLVVMAE 602
             +LI +L  ANQ++   L+ + E
Sbjct: 453 VSDLISVLREANQAINPKLLQLVE 476


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  311 bits (797), Expect = 1e-84
 Identities = 182/461 (39%), Positives = 272/461 (59%), Gaps = 14/461 (3%)

Query: 173 PVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPD 232
           P +KNFY+E    + MS+ +V  +R E   IT       + +  PKP   +         
Sbjct: 330 PFRKNFYVEVPELAKMSQEEVNVFRLEMEGITV------KGKGCPKPIKSWVQCGISMK- 382

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
           +L S+ + G  KPTPIQ+QA P I+ G DLI +A+TG+GKT+++L+P F H+  Q  S E
Sbjct: 383 ILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQR-SLE 441

Query: 293 QRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVDIIIA 351
           +  GP  +++TPTRELAL +  EC K+S   GL+ +C+YGG   + QI ++ +G +II+ 
Sbjct: 442 EGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVC 501

Query: 352 TPGRLNDLQMNNS---VNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSA 408
           TPGR+ D+   NS    NLR +TY+V+DEAD+M DM FEPQ+ +I+ +VRPDRQTVM SA
Sbjct: 502 TPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSA 561

Query: 409 TWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPND 468
           T+P  +  LA   L  P+ V VG  ++V  + V+Q +IV  E++K     E + +   + 
Sbjct: 562 TFPRAMEALARRILSKPIEVQVGGRSVVC-SDVEQQVIVIEEEKKFLKLLELLGHYQESG 620

Query: 469 KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVS 528
            VI+FV ++  AD L  D         SLHG  +Q D++  + DFK+G  K+L+ T + +
Sbjct: 621 SVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAA 680

Query: 529 RGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDR 588
           RGLD+  +  V NY  P + + YVHR G  GR G  G + T IT+  ++ AG++IK L+ 
Sbjct: 681 RGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALEL 740

Query: 589 ANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPGQRRKEFYF 629
           +  +VP DL  +   +K +QQK   +   +  G   K F F
Sbjct: 741 SGTAVPPDLEKLWSDFK-DQQKAEGKIIKKSSGFSGKGFKF 780


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  278 bits (712), Expect = 8e-75
 Identities = 163/453 (35%), Positives = 265/453 (58%), Gaps = 14/453 (3%)

Query: 170 DLPPVKKNFYIESKATSCMSEMQVINWR-KENFNITCDDLKSGEKRLIPKPTCRFKDAFQ 228
           D PP +KNFY E +  + ++  Q+I+ R K N  +      SG     P+P   F   F 
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRV------SGAAP--PRPGSSFAH-FG 259

Query: 229 QYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQP 288
               L+  I +    +PTPIQ Q  P+ L G D+I +A+TG+GKT +++ P  IH+  Q 
Sbjct: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319

Query: 289 ISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVD 347
              E  +GP  +++ PTREL   + AEC ++     L+S+ +YGG +   Q + + +G +
Sbjct: 320 -ELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378

Query: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407
           I++ TPGRL D     + NL+ ++YLV DEAD+M DM FE Q+R I   VRPDRQT++ S
Sbjct: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438

Query: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQEFVENMSP 466
           AT+   + +LA   L DP+ V  G++     +  +   I+ +   K   LT+  VE  S 
Sbjct: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTS- 497

Query: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526
           +  V++FV++K  A++L+++   +G +   LHG+ +QS++ + + DFK  +I +L+ TD+
Sbjct: 498 SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDV 557

Query: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586
            +RGLD+  +  V NYD  R+ID + HR+G  GR G+ G + TL+T +DS  AG+L++ L
Sbjct: 558 AARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNL 617

Query: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619
           + ANQ V ++L+ +A Q    ++ R +  + +K
Sbjct: 618 EGANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  278 bits (712), Expect = 8e-75
 Identities = 163/453 (35%), Positives = 265/453 (58%), Gaps = 14/453 (3%)

Query: 170 DLPPVKKNFYIESKATSCMSEMQVINWR-KENFNITCDDLKSGEKRLIPKPTCRFKDAFQ 228
           D PP +KNFY E +  + ++  Q+I+ R K N  +      SG     P+P   F   F 
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRV------SGAAP--PRPGSSFAH-FG 259

Query: 229 QYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQP 288
               L+  I +    +PTPIQ Q  P+ L G D+I +A+TG+GKT +++ P  IH+  Q 
Sbjct: 260 FDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK 319

Query: 289 ISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVD 347
              E  +GP  +++ PTREL   + AEC ++     L+S+ +YGG +   Q + + +G +
Sbjct: 320 -ELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAE 378

Query: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407
           I++ TPGRL D     + NL+ ++YLV DEAD+M DM FE Q+R I   VRPDRQT++ S
Sbjct: 379 IVVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFS 438

Query: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQEFVENMSP 466
           AT+   + +LA   L DP+ V  G++     +  +   I+ +   K   LT+  VE  S 
Sbjct: 439 ATFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTS- 497

Query: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526
           +  V++FV++K  A++L+++   +G +   LHG+ +QS++ + + DFK  +I +L+ TD+
Sbjct: 498 SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDV 557

Query: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586
            +RGLD+  +  V NYD  R+ID + HR+G  GR G+ G + TL+T +DS  AG+L++ L
Sbjct: 558 AARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNL 617

Query: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619
           + ANQ V ++L+ +A Q    ++ R +  + +K
Sbjct: 618 EGANQHVSKELLDLAMQNAWFRKSRFKGGKGKK 650


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  260 bits (665), Expect = 2e-69
 Identities = 174/465 (37%), Positives = 263/465 (56%), Gaps = 46/465 (9%)

Query: 188 MSEMQVINWR--KENFNITCDDLKSGEKRLIPKPTCRFKDAFQQYPDLLKSIIRVGIVKP 245
           + EM   +WR  +E+++IT    K G+   IP P   +KD+    P +L+ I + G  +P
Sbjct: 362 LDEMTDRDWRIFREDYSITT---KGGK---IPNPIRSWKDSSLP-PHILEVIDKCGYKEP 414

Query: 246 TPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQP-ISR--EQRNGPGMLVL 302
           TPIQ QA PI LQ  D+I VA+TG+GKT ++L+P  + + + P I R  E   GP  ++L
Sbjct: 415 TPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIIL 474

Query: 303 TPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQM 361
            PTRELA  +E E  K+    G++++ + GG +R  Q   +  G +I+IATPGRL D+  
Sbjct: 475 APTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLE 534

Query: 362 NNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDV-----RPD---------------- 400
           N  + L   TY+V+DEAD+M+DM FEP ++KIL  +     +PD                
Sbjct: 535 NRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFES 594

Query: 401 -----RQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRA 455
                RQTVM +AT P  V +LA SYL+ P +VY+G+        V+Q + + +E EKR 
Sbjct: 595 GKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPH-ERVEQKVFLMSESEKRK 653

Query: 456 LTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKS 515
                +E    +  +I+FV+QK   D L+      G +A +LHG   Q  +E A+ + K+
Sbjct: 654 KLLAILEQ-GFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKA 712

Query: 516 GNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRD 575
           G   IL+ TD+  RG+D+ DV+ V NYD  +NI+ Y+HR+G  GR GK+G ++T +T+ D
Sbjct: 713 GAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKED 772

Query: 576 SKMAGELIK-ILDRANQSVPEDLVVMAE-QYK---LNQQKRHRET 615
           S +  EL + IL+    S P +L    + Q+K   +  +KR  ET
Sbjct: 773 SAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREET 817


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  251 bits (642), Expect = 1e-66
 Identities = 144/395 (36%), Positives = 220/395 (55%), Gaps = 18/395 (4%)

Query: 244 KPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDS----QPISREQRNG--- 296
           +PTP+Q  A PII +  DL+  AQTG+GKT ++L+P    + S    + +   + NG   
Sbjct: 202 RPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYG 261

Query: 297 -----PGMLVLTPTRELALHVEAECSKYSYKGLKSICI-YGGRNRNGQIEDISKGVDIII 350
                P  LVL PTRELA+ +  E  K+SY+     C+ YGG +   QI D+ +G  +++
Sbjct: 262 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 321

Query: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL-LDVRPD---RQTVMT 406
           ATPGRL D+     + L    YLV+DEAD+MLDM FEPQIR+I+  D  P    R T+M 
Sbjct: 322 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 381

Query: 407 SATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP 466
           SAT+P  ++ LA  +L + + + VG +   + N + Q ++   E +KR+   + +     
Sbjct: 382 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSEN-ITQKVVWVEESDKRSFLLDLLNATGK 440

Query: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526
           +   ++FV  K  AD L      +G +  S+HG+  Q D+E A+  F+SG   IL+ T +
Sbjct: 441 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 500

Query: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586
            +RGLD+++V HV N+D P +I+ YVHR+G  GR G  G + +   +R+  +  +L+ +L
Sbjct: 501 AARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLL 560

Query: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPG 621
             A Q VP  L  MA ++      R R   SR  G
Sbjct: 561 VEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSG 595


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  245 bits (625), Expect = 1e-64
 Identities = 142/395 (35%), Positives = 220/395 (55%), Gaps = 18/395 (4%)

Query: 244 KPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMP--GFIHLDS--QPISREQRNG--- 296
           +PTP+Q  A PII    DL+  AQTG+GKT ++L+P    I+ D   + +   + NG   
Sbjct: 200 RPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYG 259

Query: 297 -----PGMLVLTPTRELALHVEAECSKYSYKGLKSICI-YGGRNRNGQIEDISKGVDIII 350
                P  LVL PTRELA+ +  E  K+SY+     C+ YGG +   QI D+ +G  +++
Sbjct: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319

Query: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL-LDVRPD---RQTVMT 406
           ATPGRL D+     + L    YLV+DEAD+MLDM FEPQIR+I+  D  P    R T+M 
Sbjct: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379

Query: 407 SATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP 466
           SAT+P  ++ LA  +L + + + VG +   + N + Q ++   + +KR+   + +     
Sbjct: 380 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSEN-ITQKVVWVEDLDKRSFLLDILGATGS 438

Query: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526
           +   ++FV  K  AD L      +G +  S+HG+  Q D+E A+  F+SG   IL+ T +
Sbjct: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498

Query: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586
            +RGLD+++V HV N+D P +I+ YVHR+G  GR G  G + +   +++  +  +L+ +L
Sbjct: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLL 558

Query: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPG 621
             A Q VP  L  MA ++      R R   +R  G
Sbjct: 559 VEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSG 593


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  245 bits (625), Expect = 1e-64
 Identities = 142/395 (35%), Positives = 220/395 (55%), Gaps = 18/395 (4%)

Query: 244 KPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMP--GFIHLDS--QPISREQRNG--- 296
           +PTP+Q  A PII    DL+  AQTG+GKT ++L+P    I+ D   + +   + NG   
Sbjct: 200 RPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYG 259

Query: 297 -----PGMLVLTPTRELALHVEAECSKYSYKGLKSICI-YGGRNRNGQIEDISKGVDIII 350
                P  LVL PTRELA+ +  E  K+SY+     C+ YGG +   QI D+ +G  +++
Sbjct: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 319

Query: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL-LDVRPD---RQTVMT 406
           ATPGRL D+     + L    YLV+DEAD+MLDM FEPQIR+I+  D  P    R T+M 
Sbjct: 320 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 379

Query: 407 SATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP 466
           SAT+P  ++ LA  +L + + + VG +   + N + Q ++   + +KR+   + +     
Sbjct: 380 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSEN-ITQKVVWVEDLDKRSFLLDILGATGS 438

Query: 467 NDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526
           +   ++FV  K  AD L      +G +  S+HG+  Q D+E A+  F+SG   IL+ T +
Sbjct: 439 DSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAV 498

Query: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586
            +RGLD+++V HV N+D P +I+ YVHR+G  GR G  G + +   +++  +  +L+ +L
Sbjct: 499 AARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLL 558

Query: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRKPG 621
             A Q VP  L  MA ++      R R   +R  G
Sbjct: 559 VEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSG 593


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  244 bits (624), Expect = 1e-64
 Identities = 139/372 (37%), Positives = 223/372 (59%), Gaps = 12/372 (3%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHL--DSQPIS 290
           L  +I + G  K TP+Q  + PIIL G DL+  AQTG+GKT ++L+P   H+  D    S
Sbjct: 299 LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITAS 358

Query: 291 R-EQRNGPGMLVLTPTRELALHVEAECSKYSYKG-LKSICIYGGRNRNGQIEDISKGVDI 348
           R ++   P  +++ PTREL   +  E  K+S+   ++++ IYGG      I  I +G +I
Sbjct: 359 RFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNI 418

Query: 349 IIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL----LDVRPDRQTV 404
           + ATPGRL D+     + L+ I YLV+DEAD+MLDM F P+++K++    +  +  RQT+
Sbjct: 419 LCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTL 478

Query: 405 MTSATWPDTVRQLALSYLKDP-MIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVEN 463
           M SAT+P+ +++LA  +LK   + V VG +   A   V+Q ++   +  KR    E + N
Sbjct: 479 MFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRN 537

Query: 464 MSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILIT 523
           +  +++ ++FV  K  AD +++    + IS  S+HG+ EQ ++E+A+ DF+ G   +L+ 
Sbjct: 538 IG-DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 596

Query: 524 TDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLI-TQRDSKMAGEL 582
           T + +RGLD+ +V HV N+D P  ID YVHR+G  GR G TG +++    + D+ +A  L
Sbjct: 597 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 656

Query: 583 IKILDRANQSVP 594
           +K+L  A Q VP
Sbjct: 657 VKVLTDAQQDVP 668


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  244 bits (624), Expect = 1e-64
 Identities = 139/372 (37%), Positives = 223/372 (59%), Gaps = 12/372 (3%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHL--DSQPIS 290
           L  +I + G  K TP+Q  + PIIL G DL+  AQTG+GKT ++L+P   H+  D    S
Sbjct: 299 LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITAS 358

Query: 291 R-EQRNGPGMLVLTPTRELALHVEAECSKYSYKG-LKSICIYGGRNRNGQIEDISKGVDI 348
           R ++   P  +++ PTREL   +  E  K+S+   ++++ IYGG      I  I +G +I
Sbjct: 359 RFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNI 418

Query: 349 IIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL----LDVRPDRQTV 404
           + ATPGRL D+     + L+ I YLV+DEAD+MLDM F P+++K++    +  +  RQT+
Sbjct: 419 LCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTL 478

Query: 405 MTSATWPDTVRQLALSYLKDP-MIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVEN 463
           M SAT+P+ +++LA  +LK   + V VG +   A   V+Q ++   +  KR    E + N
Sbjct: 479 MFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRN 537

Query: 464 MSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILIT 523
           +  +++ ++FV  K  AD +++    + IS  S+HG+ EQ ++E+A+ DF+ G   +L+ 
Sbjct: 538 IG-DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 596

Query: 524 TDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLI-TQRDSKMAGEL 582
           T + +RGLD+ +V HV N+D P  ID YVHR+G  GR G TG +++    + D+ +A  L
Sbjct: 597 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 656

Query: 583 IKILDRANQSVP 594
           +K+L  A Q VP
Sbjct: 657 VKVLTDAQQDVP 668


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  244 bits (624), Expect = 1e-64
 Identities = 139/372 (37%), Positives = 223/372 (59%), Gaps = 12/372 (3%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHL--DSQPIS 290
           L  +I + G  K TP+Q  + PIIL G DL+  AQTG+GKT ++L+P   H+  D    S
Sbjct: 265 LNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITAS 324

Query: 291 R-EQRNGPGMLVLTPTRELALHVEAECSKYSYKG-LKSICIYGGRNRNGQIEDISKGVDI 348
           R ++   P  +++ PTREL   +  E  K+S+   ++++ IYGG      I  I +G +I
Sbjct: 325 RFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNI 384

Query: 349 IIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL----LDVRPDRQTV 404
           + ATPGRL D+     + L+ I YLV+DEAD+MLDM F P+++K++    +  +  RQT+
Sbjct: 385 LCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTL 444

Query: 405 MTSATWPDTVRQLALSYLKDP-MIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVEN 463
           M SAT+P+ +++LA  +LK   + V VG +   A   V+Q ++   +  KR    E + N
Sbjct: 445 MFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRDVQQTVLQVGQFSKREKLVEILRN 503

Query: 464 MSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILIT 523
           +  +++ ++FV  K  AD +++    + IS  S+HG+ EQ ++E+A+ DF+ G   +L+ 
Sbjct: 504 IG-DERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVA 562

Query: 524 TDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLI-TQRDSKMAGEL 582
           T + +RGLD+ +V HV N+D P  ID YVHR+G  GR G TG +++    + D+ +A  L
Sbjct: 563 TSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQPL 622

Query: 583 IKILDRANQSVP 594
           +K+L  A Q VP
Sbjct: 623 VKVLTDAQQDVP 634


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  224 bits (570), Expect = 2e-58
 Identities = 139/396 (35%), Positives = 211/396 (53%), Gaps = 16/396 (4%)

Query: 216 IPKPTCRFKDAFQQYPD-LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTL 274
           IP P   FK+   ++P  +L+ + + GI  PTPIQ Q  P IL G D+I +A TG+GKTL
Sbjct: 176 IPPPIKSFKE--MKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTL 233

Query: 275 SYLMPGFIHLDSQP--ISREQRNGPGMLVLTPTRELALHVEAECSKY-------SYKGLK 325
            + +P  +    Q   +   +R GP  L++ P+RELA         Y       S   L+
Sbjct: 234 VFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLR 293

Query: 326 SICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDME 385
                GG +   Q+E I  GV +++ATPGRL DL     V+L    YL +DEAD+M+DM 
Sbjct: 294 CALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMG 353

Query: 386 FEPQIRKILLDVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNI 445
           FE  IR I    +  RQT++ SAT P  ++  A S L  P+ + VG     +++ + Q +
Sbjct: 354 FEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVI-QEV 412

Query: 446 IVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSD 505
               E+ K     E ++   P   V++F  +K   D +     ++G+ A ++HG  +Q +
Sbjct: 413 EYVKEEAKMVYLLECLQKTPP--PVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEE 470

Query: 506 QERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTG 565
           + +A+E F+ G   +L+ TD+ S+GLD   + HV NYD P  I+ YVHR+G  GR+G TG
Sbjct: 471 RTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTG 530

Query: 566 TSVTLITQR-DSKMAGELIKILDRANQSVPEDLVVM 600
            + T I +  D  +  +L  +L  A Q VP  L V+
Sbjct: 531 IATTFINKACDESVLMDLKALLLEAKQKVPPVLQVL 566


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  204 bits (520), Expect = 2e-52
 Identities = 124/393 (31%), Positives = 213/393 (54%), Gaps = 13/393 (3%)

Query: 231 PDLLK-SIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPI 289
           P++L  ++ + G   PTPIQ Q  P+ L G D++  A TG+GKT ++L+P  +       
Sbjct: 211 PEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMR------ 264

Query: 290 SREQRNGPGMLVLTPTRELALHVEAECSKY--SYKGLKSICIYGGRNRNGQIEDISKGVD 347
           +  +   P  L+LTPTRELA+ +E +  +       +K++ + GG     Q+  + + V 
Sbjct: 265 ALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVK 324

Query: 348 IIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTS 407
           +IIATPGRL D+   +SV L  +  +V+DEAD ML M F+ Q+  IL ++  D QT++ S
Sbjct: 325 VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVS 384

Query: 408 ATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPN 467
           AT P ++ QLA   L +P+ +  G  NL   N  +  + V    +K+ L +   +     
Sbjct: 385 ATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILNDKKLFK 444

Query: 468 DKVIMFVSQKHIADDLSSDF-NIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDI 526
             V++FV  K  AD LS     I G+ + S+H    Q +++  ++    G+ +++++T +
Sbjct: 445 PPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGV 504

Query: 527 VSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKIL 586
           + RGLDL  V  V N+D P ++D YVH++G +GR G+ GT++T I     ++  ++ K +
Sbjct: 505 LGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRV 564

Query: 587 DRANQSVPEDLVVMAEQYKLNQQKRHRETRSRK 619
                 +P  L+       L+ QKR  + + ++
Sbjct: 565 KPTGSILPPQLL---NSPYLHDQKRKEQQKDKQ 594


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  196 bits (498), Expect = 5e-50
 Identities = 117/353 (33%), Positives = 199/353 (56%), Gaps = 12/353 (3%)

Query: 223 FKDAFQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFI 282
           F+     YP + K I++ G   PTPIQ +  P+IL G D++ +A+TG+GKT  +L+P F 
Sbjct: 98  FQSMGLSYP-VFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156

Query: 283 HLDSQPISREQRNGPGMLVLTPTRELALHV---EAECSKYSYKGLKSICIYGGRNRNGQI 339
            L +       + G   L+L+PTRELAL       E  K++  GLK+  I GG     Q 
Sbjct: 157 RLKTH----SAQTGARALILSPTRELALQTLKFTKELGKFT--GLKTALILGGDRMEDQF 210

Query: 340 EDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRP 399
             + +  DIIIATPGRL  + +  S+ L+S+ Y+V DEAD++ +M F  Q+++I+  +  
Sbjct: 211 AALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPG 270

Query: 400 DRQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQE 459
             QTV+ SAT P  + + A + L +P+++ + +++      +K +  +  E  K A+   
Sbjct: 271 GHQTVLFSATLPKLLVEFARAGLTEPVLIRL-DVDTKLNEQLKTSFFLVREDTKAAVLLH 329

Query: 460 FVEN-MSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518
            + N + P D+ ++FV+ KH A+ L+     Q +S   ++   + + ++  +  F  G  
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389

Query: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLI 571
             LI TD+ +RGLD+  + +V NY FP    +++HRVG + R G++GT+ +L+
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  196 bits (498), Expect = 5e-50
 Identities = 117/353 (33%), Positives = 199/353 (56%), Gaps = 12/353 (3%)

Query: 223 FKDAFQQYPDLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFI 282
           F+     YP + K I++ G   PTPIQ +  P+IL G D++ +A+TG+GKT  +L+P F 
Sbjct: 98  FQSMGLSYP-VFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156

Query: 283 HLDSQPISREQRNGPGMLVLTPTRELALHV---EAECSKYSYKGLKSICIYGGRNRNGQI 339
            L +       + G   L+L+PTRELAL       E  K++  GLK+  I GG     Q 
Sbjct: 157 RLKTH----SAQTGARALILSPTRELALQTLKFTKELGKFT--GLKTALILGGDRMEDQF 210

Query: 340 EDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRP 399
             + +  DIIIATPGRL  + +  S+ L+S+ Y+V DEAD++ +M F  Q+++I+  +  
Sbjct: 211 AALHENPDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPG 270

Query: 400 DRQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQE 459
             QTV+ SAT P  + + A + L +P+++ + +++      +K +  +  E  K A+   
Sbjct: 271 GHQTVLFSATLPKLLVEFARAGLTEPVLIRL-DVDTKLNEQLKTSFFLVREDTKAAVLLH 329

Query: 460 FVEN-MSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518
            + N + P D+ ++FV+ KH A+ L+     Q +S   ++   + + ++  +  F  G  
Sbjct: 330 LLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKC 389

Query: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLI 571
             LI TD+ +RGLD+  + +V NY FP    +++HRVG + R G++GT+ +L+
Sbjct: 390 STLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLV 442


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  195 bits (496), Expect = 9e-50
 Identities = 130/374 (34%), Positives = 198/374 (52%), Gaps = 12/374 (3%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
           LLK+I  +G  +PTPIQ    P+ L G D+   A TGTGKT ++ +P    L  +P    
Sbjct: 229 LLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKP---R 285

Query: 293 QRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIEDISKGVDIIIA 351
           Q     +LVL PTREL + V +   + + +  + +    GG +   Q   +    DI+IA
Sbjct: 286 QAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIA 345

Query: 352 TPGRLNDLQMN-NSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 410
           TPGRL D   N  S +L SI  L++DEAD+MLD  FE Q+++I+      RQT++ SAT 
Sbjct: 346 TPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATM 405

Query: 411 PDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNII---VTTEKEKRALTQEFVENMSPN 467
            D V+ LA   LK+P+ ++V N N      ++Q  I      E ++ A+    +      
Sbjct: 406 TDEVKDLASVSLKNPVRIFV-NSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTF-T 463

Query: 468 DKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIV 527
           D V++F   K  A  +     + G+    LHGN  Q+ +  A+  FK   I IL+ TD+ 
Sbjct: 464 DHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVA 523

Query: 528 SRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILD 587
           +RGLD+  V  V N+  P  I  YVHRVG   R G+ G SV+L+ + + KM  E++K   
Sbjct: 524 ARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAK 583

Query: 588 RANQS--VPEDLVV 599
              ++  +P+D+++
Sbjct: 584 APVKARILPQDVIL 597


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  188 bits (478), Expect = 1e-47
 Identities = 135/396 (34%), Positives = 213/396 (53%), Gaps = 11/396 (2%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
           L ++  ++G  KPT IQ +A P+ LQG D+I +A+TG+GKT ++ +P    L   P    
Sbjct: 35  LCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLETP---- 90

Query: 293 QRNGPGMLVLTPTRELALHVEAECSKY-SYKGLKSICIYGGRNRNGQIEDISKGVDIIIA 351
           QR     LVLTPTRELA  +  +     S  G++S  I GG +   Q   ++K   IIIA
Sbjct: 91  QRLFA--LVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIA 148

Query: 352 TPGRLND-LQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 410
           TPGRL D L+     NLR++ YLV+DEAD++L+M+FE ++ KIL  +  DR+T + SAT 
Sbjct: 149 TPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATM 208

Query: 411 PDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKV 470
              V++L  + LK+P+   V +     V  ++Q  I    K K       +  ++ N  +
Sbjct: 209 TKKVQKLQRAALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFM 267

Query: 471 IMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRG 530
           I F S  +     +      G +A  LHG   QS +  ++  FK+    IL+ TD+ SRG
Sbjct: 268 I-FCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRG 326

Query: 531 LDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRAN 590
           LD+  V  V N+D P +   Y+HRVG   R G++G ++T +TQ D ++   +  ++ +  
Sbjct: 327 LDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKL 386

Query: 591 QSVP-EDLVVMAEQYKLNQQKRHRETRSRKPGQRRK 625
              P +D  VM    ++ + +R      R+ G+++K
Sbjct: 387 PGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKK 422


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  187 bits (476), Expect = 2e-47
 Identities = 118/368 (32%), Positives = 195/368 (52%), Gaps = 13/368 (3%)

Query: 219 PTCRFKDAFQQYP---DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLS 275
           P  + + AF  +P   + +K +   G+    PIQ++ +  +  G DLI  A+TGTGKT S
Sbjct: 180 PVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFS 239

Query: 276 YLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGLKSICIYGGRNR 335
           + +P    L  +   R++   P +LVL PTRELA  V  + S  + K L   C YGG   
Sbjct: 240 FAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKK-LSVACFYGGTPY 298

Query: 336 NGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKIL- 394
            GQ E +  G+DI++ TPGR+ D   N  ++L  + ++V+DE D+MLDM F  Q+ +IL 
Sbjct: 299 GGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILS 358

Query: 395 ----LDVRPDRQTVMTSATWPDTVRQLALSYLKD--PMIVYVGNLNLVAVNTVKQNIIVT 448
                D   + QT++ SAT P  V  +A  Y+K     +  +G        TV+   I  
Sbjct: 359 VAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKC 418

Query: 449 TEKEKRALTQEFVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQE 507
              ++ A+  + +   S +  + I+F   K  A +LS +  I+   A+SLHG+  Q  +E
Sbjct: 419 HWTQRAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQRE 477

Query: 508 RAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTS 567
             ++ F++G+  +L+ T++ +RGLD+ +V  V     P++++ Y+HR G  GR G+TG  
Sbjct: 478 ITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVC 537

Query: 568 VTLITQRD 575
           +     ++
Sbjct: 538 ICFYQHKE 545


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  185 bits (470), Expect = 1e-46
 Identities = 118/379 (31%), Positives = 203/379 (53%), Gaps = 14/379 (3%)

Query: 209 KSGEKRLIPKPTCRFKD-AFQQYP---DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIV 264
           KS + +L    T   K+ AF  +P   + +K +   G+    PIQ + +  + +G DLI 
Sbjct: 120 KSSDNKLEETLTREQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIA 179

Query: 265 VAQTGTGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYKGL 324
            A+TGTGKT S+ +P    L     + ++   P +LVL PTRELA  V  +    + K L
Sbjct: 180 QARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRK-L 238

Query: 325 KSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDM 384
              C YGG +   QI  I  G+DI++ TPGR+ D   +  ++L  + ++V+DE D+MLD+
Sbjct: 239 SVACFYGGTSYQSQINHIRNGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDL 298

Query: 385 EFEPQIRKIL-----LDVRPDRQTVMTSATWPDTVRQLALSYLKD--PMIVYVGNLNLVA 437
            F  Q+  I+      D   + QT++ SAT P  V ++A  Y+K     +  VG +   A
Sbjct: 299 GFAEQVEDIIHESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKA 358

Query: 438 VNTVKQNIIVTTEKEKRALTQEFVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAES 496
             TV+   I     ++ A+  + ++  S ++ + I+F   K    +++ + +I+  +A+ 
Sbjct: 359 ATTVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQC 417

Query: 497 LHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVG 556
           LHG+  QS +E  ++ F+ G+ K+L+ T++ +RGLD+ +V  V     P++++ Y+HR G
Sbjct: 418 LHGDIAQSQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSG 477

Query: 557 YIGRTGKTGTSVTLITQRD 575
             GR G+TG  +     R+
Sbjct: 478 RTGRAGRTGICICFYQPRE 496


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  185 bits (470), Expect = 1e-46
 Identities = 156/538 (28%), Positives = 255/538 (47%), Gaps = 54/538 (10%)

Query: 96  FGNREMKAKAKAAIETLIRKQESYNSESSV-DNAASQTPIGRNLGRNDIVGEAEPLS-NW 153
           FGN++       A +T  + Q     E S+ +    Q+   R    ++I  + E  +  W
Sbjct: 49  FGNKKSVPGVCGASQTHQKPQNGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQW 108

Query: 154 DRIRAAVVECEKRKWADLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEK 213
                A +E +K        V++    ESK TS   E    N RKE  N   +  K   +
Sbjct: 109 MSSVEAKIEDKK--------VQR----ESKLTSGKLE----NLRKEKINFLRNKHKIHVQ 152

Query: 214 RL-IPKPTCRFKDAFQQYP---DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTG 269
              +P P   F+   Q+Y     LL++I+  G   PTPIQ QA P++L G +L+  A TG
Sbjct: 153 GTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTG 212

Query: 270 TGKTLSYLMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS--------- 320
           +GKTL++ +P  + L  QP ++  R     L+++PTRELA  +  E  K S         
Sbjct: 213 SGKTLAFSIPILMQL-KQPANKGFR----ALIISPTRELASQIHRELIKISEGTGFRIHM 267

Query: 321 -YKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDLQMNN--SVNLRSITYLVIDE 377
            +K   +   +G ++        SK  DI++ TP RL  L   +   ++L S+ +LV+DE
Sbjct: 268 IHKAAVAAKKFGPKS--------SKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDE 319

Query: 378 ADKMLD---MEFEPQIRKILLDVRPDR-QTVMTSATWPDTVRQLALSYLKDPMIVYVGNL 433
           +DK+ +     F  Q+  I L     + +  M SAT+   V Q     L + + V +G  
Sbjct: 320 SDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIGAR 379

Query: 434 NLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKVIMFVSQKHIADDLSSDFNIQGIS 493
           N  AV TV+Q ++    +  + L    +     N  V++FV     A +L  +   +GI+
Sbjct: 380 NS-AVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGIN 438

Query: 494 AESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVH 553
            + +H    Q  ++  V  F++G I +LI T +++RG+D   V  V NYDFP +   Y+H
Sbjct: 439 VDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIH 498

Query: 554 RVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRANQSVPEDLVVMAEQYKLNQQKR 611
           R+G  GR G  G ++T  T+ D  +   +  ++ +A   VPE   +   Q  L++QK+
Sbjct: 499 RIGRTGRAGNKGKAITFFTEDDKPLLRSVANVIQQAGCPVPE--YIKGFQKLLSKQKK 554


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  184 bits (467), Expect = 2e-46
 Identities = 139/451 (30%), Positives = 223/451 (49%), Gaps = 40/451 (8%)

Query: 181 ESKATSCMSEMQVINWRKENFNITCDDLKSGEKRL-IPKPTCRFKDAFQQYP---DLLKS 236
           ESK TS   E    N RKE  N   +  K   +   +P P   F+   Q+Y     LL++
Sbjct: 16  ESKLTSGKLE----NLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQN 71

Query: 237 IIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISREQRNG 296
           I+  G   PTPIQ QA P++L G +L+  A TG+GKTL++ +P  + L  QP ++  R  
Sbjct: 72  ILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQL-KQPANKGFR-- 128

Query: 297 PGMLVLTPTRELALHVEAECSKYS----------YKGLKSICIYGGRNRNGQIEDISKGV 346
              L+++PTRELA  +  E  K S          +K   +   +G ++        SK  
Sbjct: 129 --ALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKS--------SKKF 178

Query: 347 DIIIATPGRLNDLQMNN--SVNLRSITYLVIDEADKMLD---MEFEPQIRKILLDVRPDR 401
           DI++ TP RL  L   +   ++L S+ +LV+DE+DK+ +     F  Q+  I L     +
Sbjct: 179 DILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHK 238

Query: 402 -QTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEF 460
            +  M SAT+   V Q     L + + V +G  N  AV TV+Q ++    +  + L    
Sbjct: 239 VRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNS-AVETVEQELLFVGSETGKLLAMRE 297

Query: 461 VENMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKI 520
           +     N  V++FV     A +L  +   +GI+ + +H    Q  ++  V  F++G I +
Sbjct: 298 LVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWV 357

Query: 521 LITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAG 580
           LI T +++RG+D   V  V NYDFP +   Y+HR+G  GR G  G ++T  T+ D  +  
Sbjct: 358 LICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLR 417

Query: 581 ELIKILDRANQSVPEDLVVMAEQYKLNQQKR 611
            +  ++ +A   VPE   +   Q  L++QK+
Sbjct: 418 SVANVIQQAGCPVPE--YIKGFQKLLSKQKK 446


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  181 bits (459), Expect = 2e-45
 Identities = 111/346 (32%), Positives = 182/346 (52%), Gaps = 11/346 (3%)

Query: 232 DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISR 291
           +LL  I  +G  KP+PIQ ++ PI L G D++  A+ GTGK+ +YL+P    LD +    
Sbjct: 106 ELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLK---- 161

Query: 292 EQRNGPGMLVLTPTRELALHVEAECSKYSYK--GLKSICIYGGRNRNGQIEDISKGVDII 349
             ++    +V+ PTRELAL V   C + S    G K +   GG N    I  +   V ++
Sbjct: 162 --KDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVHVV 219

Query: 350 IATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSAT 409
           IATPGR+ DL       +  +  +V+DEADK+L  +F   +  I+L +  +RQ ++ SAT
Sbjct: 220 IATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYSAT 279

Query: 410 WPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDK 469
           +P +V++   S+L+ P  + +  +  + +  V Q     TE++K          +  N  
Sbjct: 280 FPLSVQKFMNSHLQKPYEINL--MEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQS 337

Query: 470 VIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSR 529
           +I   S + + + L+   +  G S   +H    Q  + R   DF++G  + L+ TD+ +R
Sbjct: 338 IIFCNSSQRV-ELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTR 396

Query: 530 GLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRD 575
           G+D+  V  V N+DFP+  + Y+HR+G  GR G  G ++ LIT  D
Sbjct: 397 GIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDD 442


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  180 bits (457), Expect = 3e-45
 Identities = 108/352 (30%), Positives = 188/352 (53%), Gaps = 8/352 (2%)

Query: 232 DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISR 291
           DLL+ I   G  KP+ IQ +A   I++G D+I  +Q+GTGKT ++ +     LD Q   R
Sbjct: 48  DLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV--R 105

Query: 292 EQRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIEDISKGVDIII 350
           E +     L+L PTRELA+ ++        Y  ++     GG N    I  +  G  ++ 
Sbjct: 106 ETQ----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVA 161

Query: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 410
            TPGR+ D+    S+  R+I  LV+DEAD+ML+  F+ QI  +   + P  Q V+ SAT 
Sbjct: 162 GTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATL 221

Query: 411 PDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKV 470
           P  + ++   ++ DP+ + V    L  +  +KQ  +    +E +  T   + +     + 
Sbjct: 222 PHEILEMTNKFMTDPIRILVKRDELT-LEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 280

Query: 471 IMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRG 530
           ++F + K   D L+        +  S+HG+  Q ++E  +++F+SG  ++LI+TD+ +RG
Sbjct: 281 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARG 340

Query: 531 LDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGEL 582
           LD+  V+ + NYD P N ++Y+HR+G  GR G+ G ++  +   D ++  ++
Sbjct: 341 LDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  177 bits (448), Expect = 3e-44
 Identities = 108/366 (29%), Positives = 192/366 (52%), Gaps = 13/366 (3%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF--IHLDSQPIS 290
           LL+ I   G  KP+ IQ +A    ++G D+I  AQ+GTGKT ++ +     I LD +   
Sbjct: 43  LLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQ 102

Query: 291 REQRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIEDIS-KGVDI 348
                    LVL PTRELA  ++        Y G       GG N   +++ +  +   I
Sbjct: 103 A--------LVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHI 154

Query: 349 IIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSA 408
           I+ TPGR+ D+     ++ + I   V+DEAD+ML   F+ QI  I   +  + Q V+ SA
Sbjct: 155 IVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSA 214

Query: 409 TWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPND 468
           T P  V ++   +++DP+ + V    L      +  I V  E+ K     +  E ++   
Sbjct: 215 TMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQ 274

Query: 469 KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVS 528
            VI F++ +   D L+   + +  +  ++HG+ +Q +++  + +F+SG+ ++LITTD+++
Sbjct: 275 AVI-FINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLA 333

Query: 529 RGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDR 588
           RG+D+  V+ V NYD P N + Y+HR+G  GR G+ G ++ ++T+ D +   ++    + 
Sbjct: 334 RGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNT 393

Query: 589 ANQSVP 594
           + + +P
Sbjct: 394 SIEEMP 399


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  174 bits (442), Expect = 2e-43
 Identities = 106/364 (29%), Positives = 192/364 (52%), Gaps = 9/364 (2%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
           LL+ I   G  KP+ IQ +A    ++G D+I  AQ+GTGKT ++ +     L+ +    +
Sbjct: 44  LLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQ 103

Query: 293 QRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIEDI-SKGVDIII 350
                  LVL PTRELA  ++        Y G       GG N   +++ + ++   I++
Sbjct: 104 A------LVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVV 157

Query: 351 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 410
            TPGR+ D+     ++ + I   V+DEAD+ML   F+ QI +I   +    Q V+ SAT 
Sbjct: 158 GTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATM 217

Query: 411 PDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSPNDKV 470
           P  V ++   +++DP+ + V    L      +  I V  E+ K     +  E ++    V
Sbjct: 218 PTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAV 277

Query: 471 IMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILITTDIVSRG 530
           I F++ +   D L+   + +  +  +LHG+ +Q +++  + +F+SG+ ++LITTD+++RG
Sbjct: 278 I-FLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARG 336

Query: 531 LDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAGELIKILDRAN 590
           +D+  V+ V NYD P N + Y+HR+G  GR G+ G ++  +T+ D ++  ++    +   
Sbjct: 337 IDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTV 396

Query: 591 QSVP 594
           + +P
Sbjct: 397 EEMP 400


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  173 bits (438), Expect = 5e-43
 Identities = 118/352 (33%), Positives = 185/352 (52%), Gaps = 17/352 (4%)

Query: 233 LLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISRE 292
           L++   ++G+ +PTP+Q    P IL+G D +  A+TG+GKT ++++P    L   P    
Sbjct: 13  LVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPY--- 69

Query: 293 QRNGPGMLVLTPTRELALHVEAECSKYSYK--GLKSICIYGGRNRNGQIEDISKGVDIII 350
              G   LVLTPTRELA  + AE  +   K  GLK   I GG +   Q  ++S+   ++I
Sbjct: 70  ---GIFCLVLTPTRELAYQI-AEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVI 125

Query: 351 ATPGRLND-LQMNNSVNLRSITYLVIDEADKMLDM---EFEPQIRKILLDVRPDRQTVMT 406
           ATPGRL D L+ +N+ +++ I +LV+DEAD++L+    +F   +  IL  V   RQT++ 
Sbjct: 126 ATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLF 185

Query: 407 SATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEKRALTQEFVENMSP 466
           SAT  DT+R+L       P   +     +  V  + Q  ++  EK K A     ++    
Sbjct: 186 SATLTDTLRELQGLATNQPFF-WEAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQD 244

Query: 467 NDK---VIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILIT 523
             +   +I+F +       L            +LH   +Q ++  A+  FKS   +ILI 
Sbjct: 245 EHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIA 304

Query: 524 TDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRD 575
           TD+ SRGLD+  V  V N++ P    +Y+HRVG   R G+ G ++TL+TQ D
Sbjct: 305 TDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYD 356


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,437,667
Number of Sequences: 37866
Number of extensions: 1043180
Number of successful extensions: 3157
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2825
Number of HSP's gapped (non-prelim): 180
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.