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Search of human proteins with 55749715
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55749715 hypothetical protein LOC57536 [Homo sapiens]
(577 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55749715 hypothetical protein LOC57536 [Homo sapiens] 1160 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 54 3e-07
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 49 1e-05
gi|8923390 coiled-coil-helix-coiled-coil-helix domain containing... 48 2e-05
gi|55770834 centromere protein F [Homo sapiens] 48 3e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 48 3e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 47 4e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 47 4e-05
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 47 4e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 47 4e-05
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 47 4e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 47 4e-05
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 47 5e-05
gi|156104908 myosin heavy chain 6 [Homo sapiens] 47 5e-05
gi|215982794 myosin VA isoform 2 [Homo sapiens] 47 6e-05
gi|215982791 myosin VA isoform 1 [Homo sapiens] 47 6e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 46 1e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 45 1e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 1e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 45 1e-04
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 45 2e-04
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 45 2e-04
gi|18426913 drebrin 1 isoform b [Homo sapiens] 45 2e-04
gi|18426915 drebrin 1 isoform a [Homo sapiens] 45 2e-04
gi|38044112 restin isoform b [Homo sapiens] 44 3e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 44 4e-04
gi|4504063 golgin 97 [Homo sapiens] 44 4e-04
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 44 4e-04
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 44 5e-04
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 44 5e-04
>gi|55749715 hypothetical protein LOC57536 [Homo sapiens]
Length = 577
Score = 1160 bits (3000), Expect = 0.0
Identities = 577/577 (100%), Positives = 577/577 (100%)
Query: 1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT 60
MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT
Sbjct: 1 MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVT 60
Query: 61 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE 120
DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE
Sbjct: 61 DASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTE 120
Query: 121 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 180
ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
Sbjct: 121 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 180
Query: 181 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI 240
SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI
Sbjct: 181 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLI 240
Query: 241 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP 300
AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP
Sbjct: 241 AFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKP 300
Query: 301 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK 360
TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK
Sbjct: 301 TPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKK 360
Query: 361 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW 420
QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW
Sbjct: 361 QISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSRLDYNCLLKSNCDGW 420
Query: 421 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD 480
LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD
Sbjct: 421 LLGTSSSIKKHQDPPNSGENRKERKTVGFHSHMKDDAQWSCQKKDTCRPQRGTVTGVRKD 480
Query: 481 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN 540
ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN
Sbjct: 481 ASTSPMPTGSLKDFVTTASPSLQHTTSRYETSLLDLVQSLSPNSAPKPQRYPSREAGAWN 540
Query: 541 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 577
HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI
Sbjct: 541 HGTFRLSPLKSTRKKMGMHRTPEELEENQILEDIFFI 577
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 54.3 bits (129), Expect = 3e-07
Identities = 94/391 (24%), Positives = 161/391 (41%), Gaps = 61/391 (15%)
Query: 40 RSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSV--------DEQNSCRGEIKSA-- 89
R + KL K++ KL+ + D S SMES+ + ++ D+ + RG+ +
Sbjct: 1213 RVKQKLEKEKSEFKLE---IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQR 1269
Query: 90 SLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESF----EKKIRQLEEQNELII 145
SL +L + K R+ EL+R EEKE +L +++F E+ RQLEE+N+
Sbjct: 1270 SLSELTTQ-KSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 1328
Query: 146 KEREALQLQYRECQELLSLY---QKYLSEQQEKLTMSLSELG---------AARMQEQQV 193
ALQ +C L Y Q+ +E Q L+ + SE+ A + E+
Sbjct: 1329 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 1388
Query: 194 SSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLH 253
++K Q + A+ + +TKQR + V+D + R NSL L
Sbjct: 1389 EAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVD---VERANSL-AAALD 1444
Query: 254 HPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAAD 313
+ + DK+ +E T CE E + E +KE L ++ + A +
Sbjct: 1445 KKQRNFDKVLAEWKT-KCE----------ESQAELEASLKESRSLS---TELFKLKNAYE 1490
Query: 314 RVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQ 373
D T + ++ E + G + +E +KQI L+
Sbjct: 1491 EALDQLET-VKRENKNLEQEIADLTE----QIAENGKTIHELEKSRKQIE--------LE 1537
Query: 374 KMELEIEKERLQHLLAQQETKLLLKQQQLHQ 404
K ++++ E + L +E K+L Q +L Q
Sbjct: 1538 KADIQLALEEAEAALEHEEAKILRIQLELTQ 1568
Score = 45.1 bits (105), Expect = 2e-04
Identities = 34/149 (22%), Positives = 77/149 (51%), Gaps = 10/149 (6%)
Query: 51 DVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLIK 107
D + + ++ A +E+ +K + +++ E+ K L+D C E K+ I +L
Sbjct: 901 DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 960
Query: 108 ELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ- 166
LA+V +EK TE ++K + +++ L+E + +E++ALQ +++ + L +
Sbjct: 961 TLAKVEKEKHATENKVK----NLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEED 1016
Query: 167 --KYLSEQQEKLTMSLSELGAARMQEQQV 193
L++ + KL + +L ++ QE+++
Sbjct: 1017 KVNSLNKTKSKLEQQVEDLESSLEQEKKL 1045
Score = 38.5 bits (88), Expect = 0.017
Identities = 66/320 (20%), Positives = 142/320 (44%), Gaps = 33/320 (10%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYR-ECQELLSLY 165
KE+A + EE + T++ L E K ++LEE+ +++E+ LQLQ + E + LL
Sbjct: 848 KEMATMKEEFQKTKDELAKS----EAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAE 903
Query: 166 QK--YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--ELDGSYLSIA 215
++ L + + +L + E+ E+++++ RK +CS + ++D L++A
Sbjct: 904 ERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 963
Query: 216 R-PQTYYQTKQRPKSAVQD-SASESLIAFRNNSLKPVTLHHPK--DDLDKIPSETTTCN- 270
+ + + T+ + K+ ++ S + IA K + H + DDL + + N
Sbjct: 964 KVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNK 1023
Query: 271 CESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGH-RLAADRVHDSHPTNMTPQHPK 329
+S + E ++E ++ L+ + G +LA + + D + +
Sbjct: 1024 TKSKLEQQVEDLESSLEQEKKLR--VDLERNKRKLEGDLKLAQESILDLE-NDKQQLDER 1080
Query: 330 THPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQ-QLMLQKMELEIEKERLQHLL 388
+ YC+L ++ +TL Q + K+ Q ++++E EIE ER
Sbjct: 1081 LKKKDFEYCQLQ--------SKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAK 1132
Query: 389 AQQETKLLLKQQQLHQSRLD 408
+++ ++ + RL+
Sbjct: 1133 TEKQRSDYARELEELSERLE 1152
Score = 33.9 bits (76), Expect = 0.42
Identities = 47/224 (20%), Positives = 100/224 (44%), Gaps = 24/224 (10%)
Query: 58 RVTDASISMESLKGTGDSVDE-QNSCRGEIKSASLKDLCLE-DKRRIANLIKELARVSEE 115
+V D S+E K ++ + G++K A L LE DK+++ +K+ ++
Sbjct: 1031 QVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKK-----KD 1085
Query: 116 KEVTEERLKAEQES-----FEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLS 170
E + + K E E F+KKI++L+ + E + +E EA + + ++ S Y + L
Sbjct: 1086 FEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELE 1145
Query: 171 EQQEKLT----MSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYL--------SIARPQ 218
E E+L ++ +++ + +E + + L+ ++++ + S+A
Sbjct: 1146 ELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELG 1205
Query: 219 TYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKI 262
QR K ++ SE + + S ++ K +L+KI
Sbjct: 1206 EQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKI 1249
Score = 33.1 bits (74), Expect = 0.71
Identities = 37/177 (20%), Positives = 72/177 (40%), Gaps = 18/177 (10%)
Query: 21 SDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQN 80
S+E+ V S E +++ +L D+ + R + +++ + D V +
Sbjct: 1401 SEEQVEAVNAKCASLE---KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEW 1457
Query: 81 SCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFE--------- 131
+ E A L + L++ R ++ + +L EE E +K E ++ E
Sbjct: 1458 KTKCEESQAEL-EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQ 1516
Query: 132 -----KKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSEL 183
K I +LE+ + I E+ +QL E + L + + Q +LT SE+
Sbjct: 1517 IAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEI 1573
>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
Length = 1711
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/158 (29%), Positives = 81/158 (51%), Gaps = 13/158 (8%)
Query: 53 KLKTSR-VTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELAR 111
KL+ SR + +++ +++SL G+ ++ N + EIK + E+ R+ N I + R
Sbjct: 454 KLELSRKLQESTQTVQSLHGSSRALSNSNRDK-EIKKLN------EEIERLKNKIADSNR 506
Query: 112 VSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSE 171
+ + E T L+ E+E +++R LE+Q+ ++ +E+E L Q E E L K L +
Sbjct: 507 LERQLEDTVA-LRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKD 565
Query: 172 --QQEKLTM-SLSELGAARMQEQQVSSRKSTLQCSSVE 206
QQ KL + SEL RM E + +K + Q E
Sbjct: 566 AHQQRKLALQEFSELN-ERMAELRAQKQKVSRQLRDKE 602
>gi|8923390 coiled-coil-helix-coiled-coil-helix domain containing 3
[Homo sapiens]
Length = 227
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/162 (27%), Positives = 77/162 (47%), Gaps = 17/162 (10%)
Query: 21 SDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQN 80
+DE +++ V GI NV R K SP + S AS+S E LK V E+
Sbjct: 14 ADENENITVVKGIRLSENVIDRMKESSPSGSKSQRYSGAYGASVSDEELK---RRVAEEL 70
Query: 81 SCRGEIKSASLKDLCLEDKRRI---ANLIKELARVSEE--KEVTEERLKAEQESFEKK-- 133
+ K + ED++R+ L +E A +E+ + + ER+ +E+E + K
Sbjct: 71 ALEQAKKES-------EDQKRLKQAKELDRERAAANEQLTRAILRERICSEEERAKAKHL 123
Query: 134 IRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEK 175
RQLEE++ ++ K+ + Q +E S + + +EQ +K
Sbjct: 124 ARQLEEKDRVLKKQDAFYKEQLARLEERSSEFYRVTTEQYQK 165
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 47.8 bits (112), Expect = 3e-05
Identities = 91/366 (24%), Positives = 154/366 (42%), Gaps = 57/366 (15%)
Query: 57 SRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEK 116
S + D+S L+ TGD S ++ A + C D+ ++L +E E
Sbjct: 1488 SSLGDSSFYRALLEQTGDM-----SLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETP 1542
Query: 117 EVTE---ERLKAEQESFEKKIRQLEEQNEL--IIKEREALQLQY---RECQELLSLYQKY 168
E L++ E + + + +LEE+ E I+K +E +L+ E QEL L ++Y
Sbjct: 1543 SAPAKGVEELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQY 1602
Query: 169 LSEQ---QEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQ 225
LSE Q+KLT E+ E ++++ K + S+EL+ +AR Q Q
Sbjct: 1603 LSENEQWQQKLTSVTLEM------ESKLAAEKKQTEQLSLELE-----VARLQ--LQGLD 1649
Query: 226 RPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPA-VPTEK 284
++ +E I RN S ++ H + ++ P C+ ++ + EK
Sbjct: 1650 LSSRSLLGIDTEDAIQGRNESC-DISKEHTSETTERTPKHDVHQICDKDAQQDLNLDIEK 1708
Query: 285 MPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQ-HPKTHPESCSYCRLSWA 343
+ E +KPT +C G + S TN P KT S LS++
Sbjct: 1709 -------ITETGAVKPT-GECSGEQ--------SPDTNYEPPGEDKTQGSSECISELSFS 1752
Query: 344 SLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKERLQHLLAQQETKL--LLKQQQ 401
G AL P++ L Q + L L+ E E RL H++ ++ K+ LL + +
Sbjct: 1753 ----GPNALVPMDFLGNQ---EDIHNLQLRVKETSNENLRLLHVIEDRDRKVESLLNEMK 1805
Query: 402 LHQSRL 407
S+L
Sbjct: 1806 ELDSKL 1811
Score = 37.0 bits (84), Expect = 0.049
Identities = 35/135 (25%), Positives = 61/135 (45%), Gaps = 24/135 (17%)
Query: 109 LARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELII-------KEREALQLQYRECQEL 161
+A +E+E + LK + E+ E++++ EE EL+I E E L+ Q E
Sbjct: 2138 IAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARS 2197
Query: 162 LSLYQ---KYLSEQQEKLTMSLSE-LGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARP 217
L +++ L ++E LT + E G ++ +SS KS L+ +
Sbjct: 2198 LKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLE-------------EKE 2244
Query: 218 QTYYQTKQRPKSAVQ 232
Q Q K+ K+AV+
Sbjct: 2245 QAEIQIKEESKTAVE 2259
Score = 33.9 bits (76), Expect = 0.42
Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 21/106 (19%)
Query: 96 LEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQY 155
L+DK + ++ L + S+ +T+ L E +I QL ++ EL++KE E+LQ +
Sbjct: 2027 LKDKTHLQEKLQSLEKDSQALSLTKCEL-------ENQIAQLNKEKELLVKESESLQARL 2079
Query: 156 RECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQ 201
E EKL +S L AA +++ + + R S+ Q
Sbjct: 2080 SE-------------SDYEKLNVS-KALEAALVEKGEFALRLSSTQ 2111
Score = 32.7 bits (73), Expect = 0.93
Identities = 34/113 (30%), Positives = 52/113 (46%), Gaps = 18/113 (15%)
Query: 99 KRRIANLIKEL--ARVSEEKEVTE--------ERLKAEQESFEKKIRQLEEQNELIIKER 148
K R+ NL +EL AR ++E E E LKA+ E + +R LE I E+
Sbjct: 2335 KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEK 2394
Query: 149 EALQLQYRECQELL-------SLYQKYLSE-QQEKLTMSLSELGAARMQEQQV 193
E L + ++ QE + S ++ L E +QEK+ M A M + Q+
Sbjct: 2395 ENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQL 2447
Score = 32.0 bits (71), Expect = 1.6
Identities = 30/130 (23%), Positives = 67/130 (51%), Gaps = 12/130 (9%)
Query: 78 EQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQL 137
E+N GE++ L LE+ + + +KEL + E + + + + +Q E K+R+
Sbjct: 2642 EKNRLAGELQ------LLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREE 2695
Query: 138 EEQNELII----KEREALQLQYRECQEL-LSLYQKYLSEQQEKLTMSLSELGAARMQEQQ 192
+ +L + K+ +AL L + E+ + Y++ L+ ++E L+ E+ + +++
Sbjct: 2696 IAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEE 2755
Query: 193 V-SSRKSTLQ 201
+ +S K+T Q
Sbjct: 2756 LNNSLKATTQ 2765
Score = 30.8 bits (68), Expect = 3.5
Identities = 21/81 (25%), Positives = 40/81 (49%)
Query: 121 ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL 180
++LKA+ + KI +LE + + KE + +++E Q L + L E+++ L
Sbjct: 281 DQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCR 340
Query: 181 SELGAARMQEQQVSSRKSTLQ 201
EL Q Q S++ + L+
Sbjct: 341 DELVRTTAQYDQASTKYTALE 361
Score = 30.8 bits (68), Expect = 3.5
Identities = 35/137 (25%), Positives = 68/137 (49%), Gaps = 11/137 (8%)
Query: 66 MESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARV--SEEKEVTEERL 123
M++LK E +G++K LE+++ I L KEL+++ ++EK+ T +
Sbjct: 2775 MDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEI--LQKELSQLQAAQEKQKTGTVM 2832
Query: 124 KAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSEL 183
+ + +I++L+E E K +EA + + C L+S + L + +E L ++ L
Sbjct: 2833 DTKVDELTTEIKELKETLE--EKTKEADEYLDKYCSLLIS--HEKLEKAKEMLETQVAHL 2888
Query: 184 GAARMQEQQVSSRKSTL 200
+ Q+ + SR S L
Sbjct: 2889 CS---QQSKQDSRGSPL 2902
Score = 30.0 bits (66), Expect = 6.1
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 19/131 (14%)
Query: 91 LKDLCLEDKRRIANLIKELARVSE---EKEVTEERLKAEQESFEKKIRQLEE-----QNE 142
LK + R + +L EL + + + + E +KA+ S E +R L+E +N
Sbjct: 491 LKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQENS 550
Query: 143 LIIKERE---ALQLQYREC-QELLSLYQKYLSEQQEKLTMS-------LSELGAARMQEQ 191
L +++ + A + R+C Q+LL + ++ + +KL+ + LS L + + +
Sbjct: 551 LTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYE 610
Query: 192 QVSSRKSTLQC 202
++ K+ C
Sbjct: 611 ELKEEKTLFSC 621
Score = 30.0 bits (66), Expect = 6.1
Identities = 45/205 (21%), Positives = 87/205 (42%), Gaps = 32/205 (15%)
Query: 53 KLKTSRVTDASISMESLKGT----GDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKE 108
+++TS ++ + M + K + GD+V + N S K+ L+ + ++ + E
Sbjct: 1859 RVETSEGLNSDLEMHADKSSREDIGDNVAKVND--------SWKERFLDVENELSRIRSE 1910
Query: 109 LARVSEEKEVTEERLKAEQ----------ESFEKKIRQLEEQNELIIKEREALQ----LQ 154
A + E E L+ Q E+ +K I LEE+ ++ ER L+
Sbjct: 1911 KASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTM 1970
Query: 155 YRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSI 214
++ L L +K + QE + L ++ E +V + LQ S ++ +
Sbjct: 1971 SKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS----EL 2026
Query: 215 ARPQTYYQTKQRPKSAVQDSASESL 239
+ +T+ Q K +S +DS + SL
Sbjct: 2027 LKDKTHLQEKL--QSLEKDSQALSL 2049
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 47.8 bits (112), Expect = 3e-05
Identities = 43/176 (24%), Positives = 90/176 (51%), Gaps = 14/176 (7%)
Query: 50 ADVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLI 106
AD + + ++ I +E+ +K + +E+ E+ K L+D C E K+ I +L
Sbjct: 902 ADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE 961
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
LA+V +EK TE ++K + +++ L+E + KE++ALQ +++ + L +
Sbjct: 962 LTLAKVEKEKHATENKVK----NLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEE 1017
Query: 167 ---KYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQT 219
L++ + KL + +L + QE+++ + L+ + +L+G L +A+ T
Sbjct: 1018 DKVNILTKAKTKLEQQVDDLEGSLEQEKKL---RMDLERAKRKLEGD-LKLAQEST 1069
Score = 42.4 bits (98), Expect = 0.001
Identities = 77/396 (19%), Positives = 163/396 (41%), Gaps = 71/396 (17%)
Query: 40 RSRHKLMSPKADVKLKTSRVTDASISMESLKGTGD----SVDEQNS---CRGEIKSASLK 92
R + KL K+++K++T ++ + ++ KG + S+++Q S + E + +
Sbjct: 1215 RVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLIN 1274
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTEERL----KAEQESFEKKIRQLEEQNELIIKER 148
DL + + R+ E +R +EK+ +L +A + E+ QLEE+ +
Sbjct: 1275 DLTAQ-RARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALA 1333
Query: 149 EALQLQYRECQELLSLY---QKYLSEQQEKLTMSLSEL----------GAARMQEQQVSS 195
ALQ +C L Y Q+ +E Q L+ + SE+ R +E + +
Sbjct: 1334 HALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1393
Query: 196 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP 255
+K + E ++ A+ + +TKQR ++ V+D ++ ++ L
Sbjct: 1394 KKLAQRLQEAEEHVEAVN-AKCASLEKTKQRLQNEVED----LMLDVERSNAACAALDKK 1448
Query: 256 KDDLDKIPS------ETTTCNCESPGRKP-AVPTEKMPQEELHMKECPHLKPTPSQCCGH 308
+ + DK+ S E T E+ ++ ++ TE + ++ + L+ +
Sbjct: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRE---- 1504
Query: 309 RLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQ 368
++ +++T Q + GG + +E +KKQ+ +
Sbjct: 1505 ----NKNLQQEISDLTEQ------------------IAEGGKQIHELEKIKKQVEQ---- 1538
Query: 369 QLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQ 404
+K E++ E + L +E K+L Q +L+Q
Sbjct: 1539 ----EKCEIQAALEEAEASLEHEEGKILRIQLELNQ 1570
Score = 38.9 bits (89), Expect = 0.013
Identities = 42/177 (23%), Positives = 87/177 (49%), Gaps = 18/177 (10%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYR-ECQELLSLY 165
KE+A + EE + T++ L E K ++LEE+ ++KE+ LQLQ + E L
Sbjct: 850 KEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAE 905
Query: 166 QK--YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--ELDGSYLSIA 215
++ L + + +L + E+ +E+++++ RK +CS + ++D L++A
Sbjct: 906 ERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 965
Query: 216 R-PQTYYQTKQRPKSAVQDSAS-ESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCN 270
+ + + T+ + K+ ++ A + IA + K + H + LD + +E N
Sbjct: 966 KVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETH-QQTLDDLQAEEDKVN 1021
Score = 33.9 bits (76), Expect = 0.42
Identities = 77/391 (19%), Positives = 159/391 (40%), Gaps = 60/391 (15%)
Query: 36 EGNVRSRHKLMSPKADV-KLKTSRVTDASISMESLKGTGDSVDEQ-NSCRGEIKSASLKD 93
EG + L ++V + +T TDA E L+ + ++ +++ + K
Sbjct: 1355 EGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKC 1414
Query: 94 LCLED-KRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQ 152
LE K+R+ N +++L E L +Q +F+K + + +++ E E EA Q
Sbjct: 1415 ASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQ 1474
Query: 153 LQYR----ECQELLSLYQKYLSE------QQEKLTMSLSEL------GAARMQE-----Q 191
+ R E ++ ++Y++ L + + + L +S+L G ++ E +
Sbjct: 1475 KESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKK 1534
Query: 192 QVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVT 251
QV K +Q + L+ + S+ + Q + V+ S + IA ++ + +
Sbjct: 1535 QVEQEKCEIQAA---LEEAEASLEHEEGKILRIQLELNQVK-SEVDRKIAEKDEEIDQLK 1590
Query: 252 LHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLA 311
+H + + + +T + E R A+ +K + +L+ E +RLA
Sbjct: 1591 RNHTR----VVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEI-------QLNHANRLA 1639
Query: 312 ADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLM 371
A+ + + T + + H + AL+ E LK+Q++ ++ +
Sbjct: 1640 AESLRNYRNTQGILKETQLHLDD----------------ALRGQEDLKEQLAIVERRANL 1683
Query: 372 LQKMELEIEKERLQHLLAQQETKLLLKQQQL 402
LQ E E L L Q E + +Q+L
Sbjct: 1684 LQ-----AEIEELWATLEQTERSRKIAEQEL 1709
Score = 29.6 bits (65), Expect = 7.9
Identities = 23/116 (19%), Positives = 56/116 (48%), Gaps = 8/116 (6%)
Query: 84 GEIKSASLKDL-CLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNE 142
GE+++ ++ ++ R+ +KEL +EE RL+ + + K++ + Q E
Sbjct: 1827 GEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAE 1886
Query: 143 LIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKS 198
++ A ++R+ Q L E +E+ ++ S++ R++ ++V ++ S
Sbjct: 1887 EAEEQSNANLSKFRKLQH-------ELEEAEERADIAESQVNKLRVKSREVHTKIS 1935
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 47.4 bits (111), Expect = 4e-05
Identities = 38/150 (25%), Positives = 78/150 (52%), Gaps = 10/150 (6%)
Query: 50 ADVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLI 106
AD + + ++ I +E+ +K + ++++ E+ K L+D C E KR I +L
Sbjct: 899 ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLE 958
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
LA+V +EK TE ++K + +++ L+E + KE++ALQ +++ + L +
Sbjct: 959 LTLAKVEKEKHATENKVK----NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 167 ---KYLSEQQEKLTMSLSELGAARMQEQQV 193
L++ + KL + +L + QE++V
Sbjct: 1015 DKVNTLTKAKVKLEQQVDDLEGSLEQEKKV 1044
Score = 39.7 bits (91), Expect = 0.008
Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 14/184 (7%)
Query: 101 RIANLIKELARVSEEKEVTEE--RLKAEQESFEKKIRQLEEQNELIIKEREALQLQYREC 158
+I L+K R E + EE RLK E E + ++LEE+ +++E+ LQLQ +
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 894
Query: 159 QELLSLYQK---YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--EL 207
Q+ L+ ++ L + + +L + E+ E+++++ RK +CS + ++
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 208 DGSYLSIAR-PQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKIPSET 266
D L++A+ + + T+ + K+ ++ A I + K + LD + +E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 267 TTCN 270
N
Sbjct: 1015 DKVN 1018
Score = 38.9 bits (89), Expect = 0.013
Identities = 73/368 (19%), Positives = 146/368 (39%), Gaps = 53/368 (14%)
Query: 55 KTSRVTDASISMESLKGTGDSVDEQ-NSCRGEIKSASLKDLCLED-KRRIANLIKELARV 112
+T TDA E L+ + ++ +++ + K LE K R+ N I++L
Sbjct: 1372 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 113 SEEKEVTEERLKAEQESFEK-----KIRQLEEQNELIIKEREALQLQ---------YREC 158
E L +Q +F+K K + E Q+EL ++EA L Y E
Sbjct: 1432 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1491
Query: 159 QELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQ 218
E L +++ QE+++ +LG++ ++ + L+ +EL S L A
Sbjct: 1492 LEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ-SALEEAEAS 1550
Query: 219 TYYQTKQRPKSAVQ----DSASESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESP 274
++ + ++ ++ + E +A ++ ++ +H L + S T+ + E+
Sbjct: 1551 LEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNH----LRVVDSLQTSLDAETR 1606
Query: 275 GRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPES 334
R A+ +K + +L+ E + SH M + K
Sbjct: 1607 SRNEALRVKKKMEGDLNEME--------------------IQLSHANRMAAEAQKQVKSL 1646
Query: 335 CSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKERLQHLLAQQETK 394
S + + L A++ + LK+ I+ ++ +LQ E E L+ ++ Q E
Sbjct: 1647 QSLLKDTQIQL---DDAVRANDDLKENIAIVERRNNLLQ-----AELEELRAVVEQTERS 1698
Query: 395 LLLKQQQL 402
L +Q+L
Sbjct: 1699 RKLAEQEL 1706
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 47.4 bits (111), Expect = 4e-05
Identities = 87/400 (21%), Positives = 162/400 (40%), Gaps = 57/400 (14%)
Query: 40 RSRHKLMSPKADVKLK----TSRVTDASISMESLKGTGDSVDEQNS---CRGEIKSASLK 92
R + KL K+++K++ S + S S +++ T +V++Q S + E ++ +
Sbjct: 1216 RVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIH 1275
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKI----RQLEEQNELIIKER 148
DL ++ K R+ EL+ EEKE +L +++ +++ RQ+EE+ +
Sbjct: 1276 DLNMQ-KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMA 1334
Query: 149 EALQLQYRECQELLSLY---QKYLSEQQEKLTMSLSELG---------AARMQEQQVSSR 196
ALQ +C L Y Q+ +E Q L+ + SE+ A + E+ ++
Sbjct: 1335 HALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAK 1394
Query: 197 KSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPK 256
K Q + + + ++ + +TKQR + V+D + + TL +
Sbjct: 1395 KKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRD----LERSHTACATLDKKQ 1450
Query: 257 DDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVH 316
+ DK+ +E ES A E + ++ R A + V
Sbjct: 1451 RNFDKVLAEWKQKLDESQAELEAAQKES--------------RSLSTELFKMRNAYEEVV 1496
Query: 317 DSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKME 376
D T + K E S + G LQ E KK + + +K +
Sbjct: 1497 DQLET--LRRENKNLQEEISDLT---EQIAETGKNLQEAEKTKKLVEQ--------EKSD 1543
Query: 377 LEIEKERLQHLLAQQETKLLLKQQQLHQ--SRLDYNCLLK 414
L++ E ++ L +E+K+L Q +L Q S LD + K
Sbjct: 1544 LQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEK 1583
Score = 42.4 bits (98), Expect = 0.001
Identities = 44/185 (23%), Positives = 87/185 (47%), Gaps = 27/185 (14%)
Query: 45 LMSPKADVKLK----TSRVTDASISMESL-----------KGTGDSVDEQNSCRGEI--K 87
L+ K D++L+ T + DA E L K + ++E+ E+ K
Sbjct: 884 LLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAK 943
Query: 88 SASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKE 147
+L+D C KR I +L L +V +EK TE ++K + +++ LEE + KE
Sbjct: 944 KRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVK----NLSEEMTALEENISKLTKE 999
Query: 148 REALQLQYRECQELLSLYQ---KYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSS 204
+++LQ +++ + L + + L + KL +L + QE+++ ++ L+ +
Sbjct: 1000 KKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKL---RADLERAK 1056
Query: 205 VELDG 209
+L+G
Sbjct: 1057 RKLEG 1061
Score = 35.0 bits (79), Expect = 0.19
Identities = 39/154 (25%), Positives = 76/154 (49%), Gaps = 21/154 (13%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYR-ECQELLSLY 165
KE+A + E+ E T+E L E + ++LEE+ +++E+ LQLQ + E + L+
Sbjct: 851 KEMATMKEDFERTKEELARS----EARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAE 906
Query: 166 QKY--LSEQQEKLTMSLSELGAARMQEQQVSS----RKSTLQ--CSSVELDGSYLSIARP 217
++ L + + L + EL +E++++S +K L+ CSS++ D L +
Sbjct: 907 ERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLT 966
Query: 218 QTYYQTKQRPKSAVQD---SASESLIAFRNNSLK 248
+ ++ K A ++ + SE + A N K
Sbjct: 967 KV-----EKEKHATENKVKNLSEEMTALEENISK 995
Score = 32.7 bits (73), Expect = 0.93
Identities = 27/110 (24%), Positives = 57/110 (51%), Gaps = 5/110 (4%)
Query: 91 LKDLCLEDKRRIANLIKELARVSEEKEVTEE-RLKAEQESFEK--KIRQLEEQNELIIKE 147
LK+ +RR L++EL + E TE R +EQE + +++ L QN +I
Sbjct: 1671 LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINT 1730
Query: 148 REALQLQYRECQELL--SLYQKYLSEQQEKLTMSLSELGAARMQEQQVSS 195
++ L+ +CQ + S+ + +E++ K ++ + + A ++++Q +S
Sbjct: 1731 KKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTS 1780
Score = 31.2 bits (69), Expect = 2.7
Identities = 37/165 (22%), Positives = 75/165 (45%), Gaps = 18/165 (10%)
Query: 47 SPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLC--LED------ 98
S A+ K K + +TDA++ E LK D+ + ++ ++KDL L++
Sbjct: 1752 SRNAEEKAKKA-ITDAAMMAEELKKEQDTSAHLERMKKNLEQ-TVKDLQHRLDEAEQLAL 1809
Query: 99 ---KRRIANLIKELARVSEEKEVTEER----LKAEQESFEKKIRQLEEQNELIIKEREAL 151
K++I L + + E +V ++R LK + +E+K++++ Q E K L
Sbjct: 1810 KGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHK-YERKVKEMTYQAEEDHKNILRL 1868
Query: 152 QLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSR 196
Q + Q + Y++ E +E+ LS + + ++ + R
Sbjct: 1869 QDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAER 1913
Score = 30.0 bits (66), Expect = 6.1
Identities = 40/171 (23%), Positives = 79/171 (46%), Gaps = 16/171 (9%)
Query: 49 KADVKLKTSRVTDASISMESLKGTGDSVDE-QNSCRGEIKSASLKDLCLE-DKRRIANLI 106
K + KL+ + D S+E K ++ + G++K + + LE DK++I +
Sbjct: 1026 KINAKLE-QQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKL 1084
Query: 107 KELARVSEEKEVTEERLKAEQES-----FEKKIRQLEEQNELIIKEREALQLQYRECQEL 161
K+ +E E+++ + K + E F+KKI++L+ + E + +E EA + ++
Sbjct: 1085 KK-----KEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQ 1139
Query: 162 LSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYL 212
S + L E E+L GA Q + R++ Q +L+ + L
Sbjct: 1140 RSDLARELEEISERLE---EASGATSAQIEMNKKREAEFQKMRRDLEEATL 1187
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 47.4 bits (111), Expect = 4e-05
Identities = 79/376 (21%), Positives = 160/376 (42%), Gaps = 35/376 (9%)
Query: 50 ADVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLI 106
A+V+ + + + I +E+ +K + V+E+ E+ + L+D C E K+ I +L
Sbjct: 911 ANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLE 970
Query: 107 KELARVSEEKEVTEERLK---AEQESFEKKIRQLEEQNELIIK-EREALQLQYRECQELL 162
L + +EK TE ++K E E + I +L +++ + ++ L + E ++L
Sbjct: 971 TMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLS 1030
Query: 163 SLYQK--YLSEQQEKLTMSLSELGAARMQ-EQQVSSRKSTLQCSSVELDGSYLSIARPQT 219
SL + L +Q ++L +L + ARM E+++ + L+ + ++ S
Sbjct: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAE 1090
Query: 220 YYQTKQRPKSAVQDSA--SESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRK 277
+ K+ S + + L+A ++K + KD +K+ +E TT
Sbjct: 1091 ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQT-QIKDLKEKLEAERTT--------- 1140
Query: 278 PAVPTEKMPQEELHM-KECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQH-----PKTH 331
KM +E + ++ L + G LA + T H H
Sbjct: 1141 ----RAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLH 1196
Query: 332 PE--SCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKERLQHLLA 389
E S S + SL G ++ ++ +K+++ +D K L L+ +L E++ A
Sbjct: 1197 FETTSASLKKRHADSLAELEGQVENLQQVKQKLEKD-KSDLQLEVDDLLTRVEQMTRAKA 1255
Query: 390 QQETKLLLKQQQLHQS 405
E L +++LH++
Sbjct: 1256 NAEKLCTLYEERLHEA 1271
Score = 32.0 bits (71), Expect = 1.6
Identities = 21/94 (22%), Positives = 43/94 (45%), Gaps = 3/94 (3%)
Query: 100 RRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQ 159
RR+ IKEL +EE + R++ + + + K++ ++Q E+ + +Y++ Q
Sbjct: 1853 RRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQ 1912
Query: 160 ELLSLYQ---KYLSEQQEKLTMSLSELGAARMQE 190
L+ + + Q KL + E G +E
Sbjct: 1913 HELNEVKERAEVAESQVNKLKIKAREFGKKVQEE 1946
Score = 30.4 bits (67), Expect = 4.6
Identities = 47/198 (23%), Positives = 82/198 (41%), Gaps = 34/198 (17%)
Query: 36 EGNVRS----RHKLMSPKADVKL-------KTSRVTDASISMESLKGTGDSVDEQNSCRG 84
EG V + + KL K+D++L + ++T A + E L + + + +
Sbjct: 1216 EGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKL 1275
Query: 85 EIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELI 144
+ + DL + K ++ + E R EEKE +L E+ +F ++I L Q E
Sbjct: 1276 DKVTQLANDLAAQ-KTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKE 1334
Query: 145 IKEREAL--------------QLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQ- 189
K + AL + QY E QE+ + + LS+ +E+ RM+
Sbjct: 1335 TKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVN-------AEMVQWRMKY 1387
Query: 190 EQQVSSRKSTLQCSSVEL 207
E V R L+ + EL
Sbjct: 1388 ENNVIQRTEDLEDAKKEL 1405
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 47.4 bits (111), Expect = 4e-05
Identities = 42/176 (23%), Positives = 90/176 (51%), Gaps = 14/176 (7%)
Query: 50 ADVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLI 106
AD + + ++ I +E+ +K + +++ E+ K L+D C E K+ I +L
Sbjct: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
LA+V +EK TE ++K + +++ L+E + KE++ALQ +++ + L +
Sbjct: 963 LTLAKVEKEKHATENKVK----NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018
Query: 167 ---KYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQT 219
L++ + KL + +L + QE+++ + L+ + +L+G L +A+ T
Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKI---RMDLERAKRKLEGD-LKLAQEST 1070
Score = 43.5 bits (101), Expect = 5e-04
Identities = 84/393 (21%), Positives = 162/393 (41%), Gaps = 65/393 (16%)
Query: 40 RSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRG-EIKSASLKDLCLED 98
R + KL K+++K++ + D + +ME++ ++++ CR E + + +K E
Sbjct: 1216 RVKQKLEKEKSEMKME---IDDLASNMETVSKAKGNLEKM--CRALEDQLSEIKTKEEEQ 1270
Query: 99 KRRIANLIKELARVS----------EEKEVTEERLKAEQESFEKKI----RQLEEQNELI 144
+R I +L + AR+ +EK+ +L +++F ++I RQLEE+ +
Sbjct: 1271 QRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAK 1330
Query: 145 IKEREALQLQYRECQELLSLY---QKYLSEQQEKLTMSLSEL----------GAARMQEQ 191
ALQ +C L Y Q+ +E Q ++ + SE+ R +E
Sbjct: 1331 SALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEEL 1390
Query: 192 QVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVT 251
+ + +K + E ++ A+ + +TKQR ++ V+D +I +
Sbjct: 1391 EEAKKKLAQRLQDAEEHVEAVN-AKCASLEKTKQRLQNEVED----LMIDVERTNAACAA 1445
Query: 252 LHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLA 311
L + + DKI +E CE E + E KE L ++ + A
Sbjct: 1446 LDKKQRNFDKILAEWKQ-KCE----------ETHAELEASQKESRSLS---TELFKIKNA 1491
Query: 312 ADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLM 371
+ D T + ++ E + GG + +E +KKQ+ +
Sbjct: 1492 YEESLDQLET-LKRENKNLQQEISDLTE----QIAEGGKRIHELEKIKKQVEQ------- 1539
Query: 372 LQKMELEIEKERLQHLLAQQETKLLLKQQQLHQ 404
+K EL+ E + L +E K+L Q +L+Q
Sbjct: 1540 -EKSELQAALEEAEASLEHEEGKILRIQLELNQ 1571
Score = 37.7 bits (86), Expect = 0.029
Identities = 43/177 (24%), Positives = 85/177 (48%), Gaps = 18/177 (10%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYR-ECQELLSLY 165
KE+A + EE E T+E L E K ++LEE+ +++E+ LQLQ + E L
Sbjct: 851 KEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAE 906
Query: 166 QK--YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--ELDGSYLSIA 215
++ L + + +L + E+ E+++++ RK +CS + ++D L++A
Sbjct: 907 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 966
Query: 216 R-PQTYYQTKQRPKSAVQDSAS-ESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCN 270
+ + + T+ + K+ ++ A + IA K + H + LD + +E N
Sbjct: 967 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAH-QQTLDDLQAEEDKVN 1022
Score = 37.4 bits (85), Expect = 0.038
Identities = 77/371 (20%), Positives = 148/371 (39%), Gaps = 59/371 (15%)
Query: 55 KTSRVTDASISMESLKGTGDSVDEQ-NSCRGEIKSASLKDLCLED-KRRIANLIKELARV 112
+T TDA E L+ + ++ +++ + K LE K+R+ N +++L
Sbjct: 1376 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMID 1435
Query: 113 SEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQ-ELLSLYQKY--- 168
E L +Q +F+K + + +++ E E EA Q + R EL + Y
Sbjct: 1436 VERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEES 1495
Query: 169 ------LSEQQEKLTMSLSEL------GAARMQE-----QQVSSRKSTLQCSSVELDGSY 211
L + + L +S+L G R+ E +QV KS LQ + L+ +
Sbjct: 1496 LDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAA---LEEAE 1552
Query: 212 LSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNC 271
S+ + Q + V+ S + IA ++ + + +H + + S +T +
Sbjct: 1553 ASLEHEEGKILRIQLELNQVK-SEVDRKIAEKDEEIDQMKRNH----IRIVESMQSTLDA 1607
Query: 272 ESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKTH 331
E R A+ +K + +L+ E +R+AA+ + + T + + H
Sbjct: 1608 EIRSRNDAIRLKKKMEGDLNEMEI-------QLNHANRMAAEALRNYRNTQAILKDTQLH 1660
Query: 332 PESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKERLQHLLAQQ 391
+ AL+ E LK+Q++ ++ +LQ E E L+ L Q
Sbjct: 1661 LDD----------------ALRSQEDLKEQLAMVERRANLLQ-----AEIEELRATLEQT 1699
Query: 392 ETKLLLKQQQL 402
E + +Q+L
Sbjct: 1700 ERSRKIAEQEL 1710
Score = 31.6 bits (70), Expect = 2.1
Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 16/161 (9%)
Query: 50 ADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLC--LEDKRRIA---- 103
A+ K K + +TDA++ E LK D+ + ++ ++KDL L++ ++A
Sbjct: 1755 AEEKAKKA-ITDAAMMAEELKKEQDTSAHLERMKKNLEQ-TVKDLQHRLDEAEQLALKGG 1812
Query: 104 --NLIKELARVSEEKEVTEERLKAEQESF------EKKIRQLEEQNELIIKEREALQLQY 155
+ K ARV E + E K E+ E+K+++L Q E K LQ
Sbjct: 1813 KKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLV 1872
Query: 156 RECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSR 196
+ Q + Y++ E +E+ ++LS+ + + ++ R
Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEER 1913
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 47.4 bits (111), Expect = 4e-05
Identities = 43/143 (30%), Positives = 75/143 (52%), Gaps = 29/143 (20%)
Query: 77 DEQNSCR--GEIKSASLKD------LCLEDKRRIANLIKELARVSEEKEVTEERLKAE-- 126
D+ N C+ + A +KD + +E++R N ++EL + E + TE +LK E
Sbjct: 67 DQHNDCKILDSLVRARIKDAVQGFIINIEERR---NKLRELLALEENEYFTEMQLKKETI 123
Query: 127 ---QESFEKKIRQLEEQNELIIKER-----EALQLQYRE-CQEL----LSLYQKYLSEQQ 173
++ +K + L+E+NE KER E L Q+RE C+EL LS++QK + E++
Sbjct: 124 EEKKDRMREKTKLLKEKNE---KERQDFVAEKLDQQFRERCEELRVELLSIHQKKVCEER 180
Query: 174 EKLTMSLSELGAARMQEQQVSSR 196
+ EL ++ E+Q+ S+
Sbjct: 181 KAQIAFNEELSRQKLVEEQMFSK 203
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 47.4 bits (111), Expect = 4e-05
Identities = 36/150 (24%), Positives = 78/150 (52%), Gaps = 10/150 (6%)
Query: 50 ADVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLI 106
AD + + ++ I +E+ +K + +++ E+ K L+D C E K+ I +L
Sbjct: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
LA+V +EK TE ++K + +++ L+E + KE++ALQ +++ + L + +
Sbjct: 963 LTLAKVEKEKHATENKVK----NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE 1018
Query: 167 ---KYLSEQQEKLTMSLSELGAARMQEQQV 193
L++ + KL + +L + QE+++
Sbjct: 1019 DKVNTLTKAKTKLEQQVDDLEGSLEQEKKL 1048
Score = 42.4 bits (98), Expect = 0.001
Identities = 71/391 (18%), Positives = 156/391 (39%), Gaps = 61/391 (15%)
Query: 40 RSRHKLMSPKADVKLKTS-------RVTDASISMESLKGTGDSVDEQNSCRGEIKSASLK 92
R + KL K+++K++ + V+ A + E + T + + + E + +
Sbjct: 1216 RVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLIN 1275
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKI----RQLEEQNELIIKER 148
+L + K R+ E +R +EK+ +L +++F ++I RQLEE+ +
Sbjct: 1276 ELSAQ-KARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLA 1334
Query: 149 EALQLQYRECQELLSLY---QKYLSEQQEKLTMSLSELGAARMQE-----QQVSSRKSTL 200
ALQ +C L Y Q+ +E Q ++ + SE+ R + Q+ +
Sbjct: 1335 HALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAK 1394
Query: 201 QCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLD 260
+ + L + + + + ++ K +Q+ + +I ++ + L + + D
Sbjct: 1395 KKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD 1454
Query: 261 KIPS------ETTTCNCESPGRKP-AVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAAD 313
K+ + E T E+ ++ ++ TE + + + HL+ + +
Sbjct: 1455 KVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE--------N 1506
Query: 314 RVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQ 373
+ +++T Q + GG + +E +KKQ+ +
Sbjct: 1507 KNLQQEISDLTEQ------------------IAEGGKHIHELEKVKKQLDH--------E 1540
Query: 374 KMELEIEKERLQHLLAQQETKLLLKQQQLHQ 404
K EL+ E + L +E K+L Q +L+Q
Sbjct: 1541 KSELQTSLEEAEASLEHEEGKILRIQLELNQ 1571
Score = 41.2 bits (95), Expect = 0.003
Identities = 85/438 (19%), Positives = 174/438 (39%), Gaps = 59/438 (13%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
KE+A + EE E T+E L E K ++LEE+ +++E+ LQLQ + + L+ +
Sbjct: 851 KEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAE 906
Query: 167 K---YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--ELDGSYLSIA 215
+ L + + +L + E+ E+++++ RK +CS + ++D L++A
Sbjct: 907 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 966
Query: 216 R-PQTYYQTKQRPKSAVQDSAS-ESLIAFRNNSLKPVTLHHPK--DDLDKIPSETTTCNC 271
+ + + T+ + K+ ++ A + IA K + H + DDL + T
Sbjct: 967 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTK 1026
Query: 272 ESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGH-RLAADRVHDSHPTNMTPQHPKT 330
+ V + E+ K C L+ + G +LA + D+ + + K
Sbjct: 1027 AKTKLEQQVDDLEGSLEQ-EKKLCMDLERAKRKLEGDLKLAQESTMDTE-NDKQQLNEKL 1084
Query: 331 HPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQ-QLMLQKMELEIEKERLQHLLA 389
+ L G ++ + L Q+ + K+ Q ++++E EIE ER A
Sbjct: 1085 KKKEFEMSNLQ--------GKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKA 1136
Query: 390 QQETKLLLKQQQLHQSRLDYNCLLKSNCDGWLLGTSSSIKKHQDPPNSGENRKERKTVGF 449
+++ L ++ + RL+ G ++S + + E +K R+ +
Sbjct: 1137 EKQRSDLSRELEEISERLEE------------AGGATSAQIEMNKKREAEFQKMRRDL-- 1182
Query: 450 HSHMKDDAQWSCQKKDTCRPQRGTVTGVRKDASTSPMPTGSLKDFVTTASPSLQHTTSRY 509
+++ T +RK + S G D + L+ S
Sbjct: 1183 --------------EESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSEL 1228
Query: 510 ETSLLDLVQSLSPNSAPK 527
+ + DL ++ S K
Sbjct: 1229 KMEINDLASNMETVSKAK 1246
Score = 33.5 bits (75), Expect = 0.55
Identities = 56/231 (24%), Positives = 107/231 (46%), Gaps = 36/231 (15%)
Query: 36 EGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSC--RGEIKSASLKD 93
EG++ KL K K D ++ ES T + + N + E + ++L+
Sbjct: 1039 EGSLEQEKKLCMDLERAKRKLEG--DLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQG 1096
Query: 94 LCLEDKRRIA----NLIKEL-ARVSE-EKEVTEERL---KAEQESFEKKIRQLEEQNELI 144
+ED++ +A IKEL AR+ E E+E+ ER KAE++ + R+LEE +E +
Sbjct: 1097 K-IEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLS-RELEEISERL 1154
Query: 145 -------------IKEREA-LQLQYRECQELLSLYQKYLSEQQEKLTMSLSELG----AA 186
K+REA Q R+ +E ++ + ++K S++ELG +
Sbjct: 1155 EEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSL 1214
Query: 187 RMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASE 237
+ +Q++ KS L+ +L + ++++ + ++ R ++D SE
Sbjct: 1215 QRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCR---TLEDQLSE 1262
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 47.0 bits (110), Expect = 5e-05
Identities = 50/203 (24%), Positives = 89/203 (43%), Gaps = 22/203 (10%)
Query: 44 KLMSPKADVKLKTSRVTDASIS--MESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRR 101
KL++ KA +L +SR ++ +ESL+ D + SAS++DL ++
Sbjct: 971 KLVAVKAKKELDSSRKETQTVKEELESLRSEKDQL-----------SASMRDL-IQGAES 1018
Query: 102 IANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEE---QNELIIKEREALQLQYREC 158
NL+ E + SE+ +V +ER + E RQL Q E I + E L +
Sbjct: 1019 YKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETL 1078
Query: 159 QELLSLYQKYLSEQQEKLTMSLSELGAARMQ-EQQVSSRKSTLQCSSVELDGSYLSIARP 217
Q L + + E Q M EL A ++Q EQ++ +T+ EL+ + + +
Sbjct: 1079 QSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVN----ELEELQVQLQKE 1134
Query: 218 QTYYQTKQRPKSAVQDSASESLI 240
+ Q + V+ A ++ +
Sbjct: 1135 KKQLQKTMQELELVKKDAQQTTL 1157
Score = 40.4 bits (93), Expect = 0.004
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 18/192 (9%)
Query: 85 EIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELI 144
E+ + +KD ++ + I EL EE+ E+LK+E K+ EQ+
Sbjct: 366 EMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQH--- 422
Query: 145 IKEREALQLQYRECQELLSLYQKYLSE-QQEKLTM-----SLSELGAARMQEQQ-----V 193
RE L+ + +E+ L + +LS+ ++EKLT+ L E QE+Q
Sbjct: 423 --NREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNY 480
Query: 194 SSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLH 253
S + ++ EL S I+ Q + KQ+ S V + + AF T++
Sbjct: 481 ESLREIMEILQTELGESAGKIS--QEFESMKQQQASDVHELQQKLRTAFTEKDALLETVN 538
Query: 254 HPKDDLDKIPSE 265
+ + +K+ S+
Sbjct: 539 RLQGENEKLLSQ 550
Score = 35.0 bits (79), Expect = 0.19
Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 3/93 (3%)
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQ 152
+L + ++ L KE+ + EE V E LK+ +E++ L ++ E I E+EALQ
Sbjct: 799 NLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQ 858
Query: 153 ---LQYRECQELLSLYQKYLSEQQEKLTMSLSE 182
L+ + E L + L Q E+++ + S+
Sbjct: 859 SDLLEMKNANEKTRLENQNLLIQVEEVSQTCSK 891
Score = 33.9 bits (76), Expect = 0.42
Identities = 70/392 (17%), Positives = 150/392 (38%), Gaps = 70/392 (17%)
Query: 43 HKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRI 102
+K+ + ++K++ + + SL+ + +E+N+ +K L ++ K+ +
Sbjct: 1181 NKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNT--------KIKQLLVKTKKEL 1232
Query: 103 ANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKER----EALQLQYREC 158
A + + + + + LK E E+ ++++ + Q I E+ E L+ +
Sbjct: 1233 A----DSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQH 1288
Query: 159 QELLSLYQKYLSEQQEKLTMS-------LSELGAARMQEQQVSSRKSTLQCSSVELDGSY 211
Q LS YQ+ ++ QE+ + SE + +++ V ++ S E +G+
Sbjct: 1289 QRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAK 1348
Query: 212 LSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDL----DKIPSETT 267
+ + K +QDS + I N + TL D L +K+ ET
Sbjct: 1349 ---QEREHLEMLIDQLKIKLQDSQNNLQI----NVSELQTLQSEHDTLLERHNKMLQETV 1401
Query: 268 TCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQH 327
+ E + ++ +E M + H + T SQ ++ +H
Sbjct: 1402 SKEAELREKLCSIQSENMMMKSEHTQ-------TVSQLTSQNEVLRNSFRDQVRHLQEEH 1454
Query: 328 PKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKERLQHL 387
KT +ETL++Q+S ++ Q +L+ E +
Sbjct: 1455 RKT------------------------VETLQQQLS-----KMEAQLFQLKNEPTTRSPV 1485
Query: 388 LAQQETKLLLKQQQLHQSRLDYNCLLKSNCDG 419
+QQ K L +++ LD + + + +G
Sbjct: 1486 SSQQSLKNLRERRNTDLPLLDMHTVTREEGEG 1517
Score = 30.4 bits (67), Expect = 4.6
Identities = 25/101 (24%), Positives = 49/101 (48%), Gaps = 24/101 (23%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
+ LA+++EEK + + EK+I+ L+E++ + +C+EL SL +
Sbjct: 788 ESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVV-------------QCEELKSLLR 834
Query: 167 KYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVEL 207
Y +QEK+ + R + +++ S K LQ +E+
Sbjct: 835 DY---EQEKVLL--------RKELEEIQSEKEALQSDLLEM 864
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 47.0 bits (110), Expect = 5e-05
Identities = 37/149 (24%), Positives = 78/149 (52%), Gaps = 10/149 (6%)
Query: 51 DVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLIK 107
D + + ++ I +E+ +K + ++++ E+ K L+D C E K+ I +L
Sbjct: 902 DAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLEL 961
Query: 108 ELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ- 166
LA+V +EK TE ++K + +++ L+E + KE++ALQ +++ + L + +
Sbjct: 962 TLAKVEKEKHATENKVK----NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEED 1017
Query: 167 --KYLSEQQEKLTMSLSELGAARMQEQQV 193
LS+ + KL + +L + QE++V
Sbjct: 1018 KVNSLSKSKVKLEQQVDDLEGSLEQEKKV 1046
Score = 44.7 bits (104), Expect = 2e-04
Identities = 83/385 (21%), Positives = 154/385 (40%), Gaps = 44/385 (11%)
Query: 40 RSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSV-----DEQNSCRGEIKSA--SLK 92
R + KL K++ KL+ VT + K + V D+ N R +++ A SL
Sbjct: 1214 RVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLN 1273
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKI----RQLEEQNELIIKER 148
D + + ++ ELAR EEKE +L + S+ +++ RQLEE+ +
Sbjct: 1274 DFTTQ-RAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332
Query: 149 EALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELD 208
ALQ +C L EQ E+ T + +EL Q+V S K+ + +
Sbjct: 1333 HALQSARHDCD--------LLREQYEEETEAKAEL-------QRVLS-KANSEVAQWRTK 1376
Query: 209 GSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKIPSETTT 268
+I R + + K++ +QD+ S T H +++++ + +
Sbjct: 1377 YETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1436
Query: 269 CNCESPG-RKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQH 327
N + K +K+ E E + SQ L+ + + + +H
Sbjct: 1437 SNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEH 1496
Query: 328 PKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM--ELEIEKERLQ 385
+T + I L +Q+ E K L+K+ +LE+EK LQ
Sbjct: 1497 LETFKR-------------ENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ 1543
Query: 386 HLLAQQETKLLLKQQQLHQSRLDYN 410
L + E L ++ ++ +++L++N
Sbjct: 1544 SALEEAEASLEHEEGKILRAQLEFN 1568
Score = 36.2 bits (82), Expect = 0.084
Identities = 71/368 (19%), Positives = 143/368 (38%), Gaps = 53/368 (14%)
Query: 55 KTSRVTDASISMESLKGTGDSVDEQ-NSCRGEIKSASLKDLCLED-KRRIANLIKELARV 112
+T TDA E L+ + ++ +++ + K LE K R+ N I++L
Sbjct: 1374 RTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 113 SEEKEVTEERLKAEQESFEK-----KIRQLEEQNELIIKEREALQLQ---------YREC 158
E L +Q +F+K K + E Q+EL ++EA L Y E
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEES 1493
Query: 159 QELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQ 218
E L +++ QE+++ +LG ++ + L+ +EL S L A
Sbjct: 1494 LEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQ-SALEEAEAS 1552
Query: 219 TYYQTKQRPKSAVQ----DSASESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESP 274
++ + ++ ++ + E +A ++ ++ +H + + S T+ + E+
Sbjct: 1553 LEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQR----VVDSLQTSLDAETR 1608
Query: 275 GRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPES 334
R + +K + +L+ E + SH M + K
Sbjct: 1609 SRNEVLRVKKKMEGDLNEME--------------------IQLSHANRMAAEAQKQVKSL 1648
Query: 335 CSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKERLQHLLAQQETK 394
S + + L A++ + LK+ I+ ++ +LQ E E L+ ++ Q E
Sbjct: 1649 QSLLKDTQIQL---DDAVRANDDLKENIAIVERRNNLLQ-----AELEELRAVVEQTERS 1700
Query: 395 LLLKQQQL 402
L +Q+L
Sbjct: 1701 RKLAEQEL 1708
Score = 35.8 bits (81), Expect = 0.11
Identities = 44/185 (23%), Positives = 90/185 (48%), Gaps = 21/185 (11%)
Query: 101 RIANLIKELARVSEEKEVTEE--RLKAEQESFEKKIRQLEEQNELIIKEREALQLQYREC 158
+I L+K E + EE R+K E E + ++LEE+ +++E+ LQLQ +
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAE 896
Query: 159 QELLSLYQK---YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--EL 207
Q+ L+ ++ L + + +L + E+ E+++++ RK +CS + ++
Sbjct: 897 QDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
Query: 208 DGSYLSIAR-PQTYYQTKQRPKSAVQDSAS-ESLIAFRNNSLKPVTLHHPK--DDL---- 259
D L++A+ + + T+ + K+ ++ A + +IA K + H + DDL
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEE 1016
Query: 260 DKIPS 264
DK+ S
Sbjct: 1017 DKVNS 1021
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 46.6 bits (109), Expect = 6e-05
Identities = 33/118 (27%), Positives = 67/118 (56%), Gaps = 6/118 (5%)
Query: 85 EIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELI 144
E K A+ + L L+++ IA L K+L + EK+ EE ++ E+ + L+E+N L+
Sbjct: 977 EAKVATGRVLSLQEE--IAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLL 1034
Query: 145 IKEREALQLQ-YRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQ 201
+E+EAL + ++ +E+ +K L E+ ++L + L++ R++ Q + + S L+
Sbjct: 1035 KQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLND---ERLRYQNLLNEFSRLE 1089
Score = 29.6 bits (65), Expect = 7.9
Identities = 24/83 (28%), Positives = 47/83 (56%), Gaps = 14/83 (16%)
Query: 67 ESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRI-ANLIKELARVS----------EE 115
E+L+G S+ E+N+ + ++ + +L+ L + RI A+L E+ R++ E+
Sbjct: 1338 EALRGEIQSLKEENNRQQQLLAQNLQ---LPPEARIEASLQHEITRLTNENLDLMEQLEK 1394
Query: 116 KEVTEERLKAEQESFEKKIRQLE 138
++ T +LK + + F KKI +LE
Sbjct: 1395 QDKTVRKLKKQLKVFAKKIGELE 1417
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 46.6 bits (109), Expect = 6e-05
Identities = 33/118 (27%), Positives = 67/118 (56%), Gaps = 6/118 (5%)
Query: 85 EIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELI 144
E K A+ + L L+++ IA L K+L + EK+ EE ++ E+ + L+E+N L+
Sbjct: 977 EAKVATGRVLSLQEE--IAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLL 1034
Query: 145 IKEREALQLQ-YRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQ 201
+E+EAL + ++ +E+ +K L E+ ++L + L++ R++ Q + + S L+
Sbjct: 1035 KQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLND---ERLRYQNLLNEFSRLE 1089
Score = 29.6 bits (65), Expect = 7.9
Identities = 24/83 (28%), Positives = 47/83 (56%), Gaps = 14/83 (16%)
Query: 67 ESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRI-ANLIKELARVS----------EE 115
E+L+G S+ E+N+ + ++ + +L+ L + RI A+L E+ R++ E+
Sbjct: 1365 EALRGEIQSLKEENNRQQQLLAQNLQ---LPPEARIEASLQHEITRLTNENLDLMEQLEK 1421
Query: 116 KEVTEERLKAEQESFEKKIRQLE 138
++ T +LK + + F KKI +LE
Sbjct: 1422 QDKTVRKLKKQLKVFAKKIGELE 1444
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/155 (21%), Positives = 75/155 (48%), Gaps = 7/155 (4%)
Query: 90 SLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKE-- 147
S +L +K +A+ ++ + +EE E+L+A QE ++ +LEE+ E +++
Sbjct: 596 SANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGA 655
Query: 148 --REALQLQYRECQEL---LSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQC 202
R L+ +R+ ++L S+ K L E +E L+ + + + ++ +V+ + +
Sbjct: 656 RVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEA 715
Query: 203 SSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASE 237
VEL+ S + + Q SA+ +S ++
Sbjct: 716 GRVELELSMTKLRAEEASLQDSLSKLSALNESLAQ 750
Score = 39.3 bits (90), Expect = 0.010
Identities = 39/176 (22%), Positives = 82/176 (46%), Gaps = 12/176 (6%)
Query: 50 ADVKLKTSRVTDASISMESLKGTGDSVDE-----QNSCRGEIKSASLKDLCLEDKR-RIA 103
AD ++K + +++E L G V+E ++ RG ++ + L R +
Sbjct: 1694 ADSEVKAGTL---QLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNL 1750
Query: 104 NLIKELARVSEEKEVTEERLKAEQESFEKKIRQ---LEEQNELIIKEREALQLQYRECQE 160
+L K L +++V +ERL A +++ + +Q L EQ + + E L+LQ E +
Sbjct: 1751 HLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEG 1810
Query: 161 LLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIAR 216
L ++ L ++QE +L+ + + + + + R +LQ + +L+ + R
Sbjct: 1811 QLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVER 1866
Score = 38.1 bits (87), Expect = 0.022
Identities = 33/148 (22%), Positives = 65/148 (43%), Gaps = 3/148 (2%)
Query: 63 SISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEE-KEVTEE 121
S+ ME K S EQ+ ++ L+DL + + A +E+ R+ E+ +++ ++
Sbjct: 1089 SLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQ 1148
Query: 122 R--LKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMS 179
R E E ++R LE+ + + +E Q + RE QE + ++ E + L
Sbjct: 1149 RDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEG 1208
Query: 180 LSELGAARMQEQQVSSRKSTLQCSSVEL 207
E A R +++ S + + L
Sbjct: 1209 AKEREALRRSNEELRSAVKKAESERISL 1236
Score = 35.4 bits (80), Expect = 0.14
Identities = 50/232 (21%), Positives = 100/232 (43%), Gaps = 32/232 (13%)
Query: 44 KLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNS---CRGEIKSASLKDLCLEDKR 100
+L++ + + + + T + E+L+G+ V Q + R E A + L L +
Sbjct: 884 QLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKE- 942
Query: 101 RIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREAL--------- 151
L ELA + ++ T+E+ ++E +K+ Q E + + ++E+ A
Sbjct: 943 ---TLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQ 999
Query: 152 ---QLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELD 208
+ +RE + + Q L +QE+L L +++++S + LQ E
Sbjct: 1000 REKEAAWRELEAERAQLQSQLQREQEEL------LARLEAEKEELSEEIAALQQERDE-- 1051
Query: 209 GSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLD 260
G L+ + Q K+ K+A+ SE L+ R +SL ++L + D
Sbjct: 1052 GLLLAESEKQQALSLKESEKTAL----SEKLMGTR-HSLATISLEMERQKRD 1098
Score = 35.4 bits (80), Expect = 0.14
Identities = 40/211 (18%), Positives = 85/211 (40%), Gaps = 17/211 (8%)
Query: 53 KLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDK------RRIANLI 106
+++ R + S + + K +S + + S G + +L L+++ R +
Sbjct: 1541 EMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQA-ELALQEESVRRSERERRATL 1599
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKI----------RQLEEQNELIIKEREALQLQYR 156
++A + + TE L+A QE K R+L+E + L+LQ R
Sbjct: 1600 DQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRR 1659
Query: 157 ECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIAR 216
+ L + LS+++ + + + + Q + TLQ + L+G+ +
Sbjct: 1660 SLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEE 1719
Query: 217 PQTYYQTKQRPKSAVQDSASESLIAFRNNSL 247
+ + K R + +S SL + R+ +L
Sbjct: 1720 SEGALRDKVRGLTEALAQSSASLNSTRDKNL 1750
Score = 33.5 bits (75), Expect = 0.55
Identities = 67/338 (19%), Positives = 131/338 (38%), Gaps = 65/338 (19%)
Query: 102 IANLIKELARVSEEKEVTEERLK----------AEQESFEKKIRQLEEQNELIIKER--- 148
+ L K+L+ E+ EE+L+ E ++++++L NEL+ +E+
Sbjct: 549 LGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNL 608
Query: 149 -EALQLQYRECQEL------LSLYQKYLSEQQEKLTMSLS-----------ELGAARMQE 190
+LQ+ ++ +EL L Q+ L Q+++L EL + Q
Sbjct: 609 AHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQL 668
Query: 191 QQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPV 250
+Q+ ++S L VE+ +++R Q K+ V ++ +++ L
Sbjct: 669 EQLEGKRSVLAKELVEVRE---ALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMT 725
Query: 251 TLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKE-CPHLKPTPSQCCGHR 309
L + L S+ + N E + Q++L + L+ S G +
Sbjct: 726 KLRAEEASLQDSLSKLSALN------------ESLAQDKLDLNRLVAQLEEEKSALQGRQ 773
Query: 310 LAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHG-GGALQPIETLKKQISEDRKQ 368
A++ + E RL G G+L +++E ++
Sbjct: 774 RQAEQ---------EATVAREEQERLEELRLEQEVARQGLEGSL--------RVAEQAQE 816
Query: 369 QLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSR 406
L Q L E+ +LQ LAQ +L ++Q+L Q+R
Sbjct: 817 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQAR 854
Score = 33.5 bits (75), Expect = 0.55
Identities = 42/177 (23%), Positives = 76/177 (42%), Gaps = 39/177 (22%)
Query: 42 RHKLMSPKADV-----KLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCL 96
R L + KA+V K + RV + +SM L+ S+ + S K ++L +
Sbjct: 696 RDMLQAEKAEVAEALTKAEAGRV-ELELSMTKLRAEEASLQDSLS-----KLSALNESLA 749
Query: 97 EDKRRIANLIKEL-----------------ARVSEEKEVTEERLKAEQE----SFEKKIR 135
+DK + L+ +L A V+ E++ E L+ EQE E +R
Sbjct: 750 QDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLR 809
Query: 136 QLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQ 192
E+ E + ++ L+ + + QE L+ + LS +++ EL AR + Q+
Sbjct: 810 VAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQ-------ELEQARREAQR 859
Score = 30.4 bits (67), Expect = 4.6
Identities = 40/176 (22%), Positives = 76/176 (43%), Gaps = 11/176 (6%)
Query: 36 EGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLC 95
EG + + + + + +L R+ ++ L+ V E+++ R E +L+
Sbjct: 1824 EGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREV-ERSALRLEKDRVALRRTL 1882
Query: 96 LEDKRRIANLIKELARVSEEKEVTEERL---KAEQESFEKKIRQLEEQNELIIKEREALQ 152
+ +R ++ R+S EK + L + E +++I+QLE Q ++ + Q
Sbjct: 1883 DKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQ 1942
Query: 153 LQYRECQELLSLYQKY--LSEQQEKLTMSLSELGAARMQ-----EQQVSSRKSTLQ 201
L+ Q+ L L Q+ L Q + +L A Q E+QVS+ K LQ
Sbjct: 1943 LEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQ 1998
Score = 30.0 bits (66), Expect = 6.1
Identities = 25/109 (22%), Positives = 48/109 (44%), Gaps = 2/109 (1%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
+ L + E+EV + L+ E+ LE+Q + ER LQ Q + LS +
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 847
Query: 167 KYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTL--QCSSVELDGSYLS 213
+ L + + + + L A +++ ++ + L Q + E +G LS
Sbjct: 848 QELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLS 896
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 45.4 bits (106), Expect = 1e-04
Identities = 73/380 (19%), Positives = 148/380 (38%), Gaps = 43/380 (11%)
Query: 44 KLMSPKADVKLKTSRVTDASISMESLKG--TGDSVDEQNSCRG-EIKSASLKDLCLE--- 97
+LM+ K ++ + T+ E L+ T + + C E + ++ C
Sbjct: 877 QLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQA 936
Query: 98 DKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRE 157
+K+++ I+EL EE+E ++L+ E+ + E K+++LEE+ ++ + L + +
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKL 996
Query: 158 CQELLSLYQKYLSEQQEK--------------LTMSLSELGAARMQEQQVSSRKSTLQCS 203
++ ++ + L+E++EK +T L Q Q++ + L+
Sbjct: 997 LEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD 1056
Query: 204 SVELDGS----YLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDL 259
S +L IA + K+ A E A +N +LK + ++
Sbjct: 1057 STDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEE-AAQKNMALKKI-----RELE 1110
Query: 260 DKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSH 319
+I E R A ++ EEL + S L + R + +
Sbjct: 1111 SQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
Query: 320 PTNMT-PQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELE 378
T + KTH R + Q +E L +Q+ + ++ + L+K +
Sbjct: 1171 ILKKTLEEEAKTHEAQIQEMRQKHS---------QAVEELAEQLEQTKRVKANLEKAKQT 1221
Query: 379 IEKERLQHLLAQQETKLLLK 398
+E ER + E K+LL+
Sbjct: 1222 LENERGE---LANEVKVLLQ 1238
Score = 36.6 bits (83), Expect = 0.065
Identities = 41/150 (27%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 40 RSRHKLMSPKADV-KLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLED 98
R+ + M KA++ +L T+ M S G SV E E +L+ E
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL-----EKSKRALEQQVEEM 1537
Query: 99 KRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYREC 158
K ++ L EL + K E L+A + FE+ ++ +EQ+E ++++ L Q RE
Sbjct: 1538 KTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSE---EKKKQLVRQVREM 1594
Query: 159 QELLSLYQKYLS---EQQEKLTMSLSELGA 185
+ L +K S ++KL M L +L A
Sbjct: 1595 EAELEDERKQRSMAVAARKKLEMDLKDLEA 1624
Score = 33.5 bits (75), Expect = 0.55
Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 7/121 (5%)
Query: 78 EQNSCRGEIKSASLKD-LCLEDKRR----IANLIKELARVSEEKEVTEERLKAEQESFEK 132
E++ EI ++S K L LE+KRR IA L +EL E+ +RLK ++
Sbjct: 1702 ERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQ 1761
Query: 133 KIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGA--ARMQE 190
L + K A Q R+ +EL Q+ + K S++ L A A+++E
Sbjct: 1762 INTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE 1821
Query: 191 Q 191
Q
Sbjct: 1822 Q 1822
Score = 32.7 bits (73), Expect = 0.93
Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 12/147 (8%)
Query: 58 RVTDASISMESLKGTGDSVDEQNSCRGEIKSA------SLKDLCLEDKRRIANLIKELAR 111
+VT + ++++ G D ++S + SA ++L E+ R+ +L +L +
Sbjct: 1274 KVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333
Query: 112 VSEEKEVTEERLKAEQE---SFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQK- 167
V +EK E+L+ E+E + EK+I L Q + K+ E +E+ QK
Sbjct: 1334 VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKD 1393
Query: 168 --YLSEQQEKLTMSLSELGAARMQEQQ 192
LS++ E+ + +L + + QQ
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQ 1420
Score = 32.0 bits (71), Expect = 1.6
Identities = 23/57 (40%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 107 KELARVSEEKEVT-EERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELL 162
KEL +E E T + + KA + E KI QLEEQ + KER+A Q R ++ L
Sbjct: 1788 KELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844
Score = 30.4 bits (67), Expect = 4.6
Identities = 68/315 (21%), Positives = 131/315 (41%), Gaps = 71/315 (22%)
Query: 101 RIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQE 160
R+ +K L +VS ++E E + E+E + + +QL +N L E E LQ Q E
Sbjct: 829 RLFTKVKPLLQVSRQEE---EMMAKEEELVKVREKQLAAENRL--TEMETLQSQL--MAE 881
Query: 161 LLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQ--CSSVELDGSYLSIARPQ 218
L L ++ +E + L EL A +++++K L+ C +E + +
Sbjct: 882 KLQLQEQLQAETE--LCAEAEELRA------RLTAKKQELEEICHDLE-----ARVEEEE 928
Query: 219 TYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKP 278
Q Q K +Q + E L+ K L+K+ +E
Sbjct: 929 ERCQHLQAEKKKMQQNIQE-----LEEQLEEEESARQKLQLEKVTTE------------- 970
Query: 279 AVPTEKMPQEELHMKE--CPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCS 336
+K+ +E++ +++ C K +L DR+ + TN+T + K+
Sbjct: 971 -AKLKKLEEEQIILEDQNCKLAKE-------KKLLEDRIAE-FTTNLTEEEEKSK----- 1016
Query: 337 YCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKE---------RLQHL 387
S A L + A+ I L++++ + KQ+ L+K ++E + LQ
Sbjct: 1017 ----SLAKLKNKHEAM--ITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 388 LAQQETKLLLKQQQL 402
+A+ + +L K+++L
Sbjct: 1071 IAELKMQLAKKEEEL 1085
Score = 30.0 bits (66), Expect = 6.1
Identities = 38/134 (28%), Positives = 58/134 (43%), Gaps = 18/134 (13%)
Query: 79 QNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLE 138
Q++C E K L E+K A +E R E E E+ KA S + + +
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERDRA--EAEAREKETKA--LSLARALEEAM 1489
Query: 139 EQNELIIKEREALQLQYR-ECQELLSLYQKYLSEQQEKLTMSLSEL-GAARMQEQQVSSR 196
EQ E E L Q+R E ++L+S ++ + S+ EL + R EQQV
Sbjct: 1490 EQK----AELERLNKQFRTEMEDLMS--------SKDDVGKSVHELEKSKRALEQQVEEM 1537
Query: 197 KSTLQCSSVELDGS 210
K+ L+ EL +
Sbjct: 1538 KTQLEELEDELQAT 1551
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/150 (24%), Positives = 77/150 (51%), Gaps = 10/150 (6%)
Query: 50 ADVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLI 106
AD + + ++ I +E+ +K + +++ E+ K L+D C E K+ I +L
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
LA+V +EK TE ++K + +++ L+E + KE++ALQ +++ + L +
Sbjct: 965 LTLAKVEKEKHATENKVK----NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 167 ---KYLSEQQEKLTMSLSELGAARMQEQQV 193
L++ + KL + +L + QE+++
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKL 1050
Score = 41.2 bits (95), Expect = 0.003
Identities = 81/389 (20%), Positives = 153/389 (39%), Gaps = 57/389 (14%)
Query: 40 RSRHKLMSPKADVKLK-------TSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLK 92
R + KL K+++K++ V+ A ++E + T + + + E + +
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIN 1277
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKI----RQLEEQNELIIKER 148
DL + + R+ E +R +EKE +L +++F ++I RQLEE+ +
Sbjct: 1278 DLTAQ-RGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 149 EALQLQYRECQELLSLYQKYLSEQQEKLTMSLS-------------ELGAARMQEQQVSS 195
ALQ +C L Y++ E + +L +LS E A + E+ +
Sbjct: 1337 HALQSSRHDCDLLREQYEEE-QESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEA 1395
Query: 196 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP 255
+K Q + A+ + +TKQR ++ V+D ++ + L
Sbjct: 1396 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED----LMLDVERTNAACAALDKK 1451
Query: 256 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV 315
+ + DKI +E CE E + E KE L ++ + A +
Sbjct: 1452 QRNFDKILAEWKQ-KCE----------ETHAELEASQKEARSL---GTELFKIKNAYEES 1497
Query: 316 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM 375
D T + ++ E + GG + +E +KKQ+ + +K
Sbjct: 1498 LDQLET-LKRENKNLQQEISDLTE----QIAEGGKRIHELEKIKKQVEQ--------EKC 1544
Query: 376 ELEIEKERLQHLLAQQETKLLLKQQQLHQ 404
EL+ E + L +E K+L Q +L+Q
Sbjct: 1545 ELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Score = 37.0 bits (84), Expect = 0.049
Identities = 42/177 (23%), Positives = 86/177 (48%), Gaps = 18/177 (10%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYR-ECQELLSLY 165
KE+A + EE + ++K E E K ++LEE+ ++KE+ LQLQ + E + L
Sbjct: 853 KEMATMKEEFQ----KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908
Query: 166 QK--YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--ELDGSYLSIA 215
++ L + + +L + E+ E+++++ RK +CS + ++D L++A
Sbjct: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 968
Query: 216 R-PQTYYQTKQRPKSAVQDSAS-ESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCN 270
+ + + T+ + K+ ++ A + IA K + H + LD + +E N
Sbjct: 969 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAH-QQTLDDLQAEEDKVN 1024
Score = 35.8 bits (81), Expect = 0.11
Identities = 78/405 (19%), Positives = 160/405 (39%), Gaps = 67/405 (16%)
Query: 20 FSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISM-ESLKGTGDSVDE 78
+ +E++S + ++ N + D +T + +A + + L+ + V+
Sbjct: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412
Query: 79 QNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLE 138
N+ K ASL+ + K+R+ N +++L E L +Q +F+K + + +
Sbjct: 1413 VNA-----KCASLE----KTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463
Query: 139 EQNELIIKEREALQLQYREC-QELLSLYQKY---------LSEQQEKLTMSLSEL----- 183
++ E E EA Q + R EL + Y L + + L +S+L
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523
Query: 184 -GAARMQE-----QQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASE 237
G R+ E +QV K LQ + L+ + S+ + Q + V+ S +
Sbjct: 1524 EGGKRIHELEKIKKQVEQEKCELQAA---LEEAEASLEHEEGKILRIQLELNQVK-SEVD 1579
Query: 238 SLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPH 297
IA ++ + + +H + + S +T + E R A+ +K + +L+ E
Sbjct: 1580 RKIAEKDEEIDQLKRNH----IRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME--- 1632
Query: 298 LKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIET 357
+ +H M + + + + + + +H AL+ E
Sbjct: 1633 -----------------IQLNHANRMAAEALRNYRNTQGILK---DTQIHLDDALRSQED 1672
Query: 358 LKKQISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQL 402
LK+Q++ ++ +LQ E E L+ L Q E + +Q+L
Sbjct: 1673 LKEQLAMVERRANLLQ-----AEIEELRATLEQTERSRKIAEQEL 1712
Score = 33.1 bits (74), Expect = 0.71
Identities = 47/238 (19%), Positives = 101/238 (42%), Gaps = 35/238 (14%)
Query: 55 KTSRVTDASISMES-LKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVS 113
K + +T A I +E + S++++ R +++ A K LE ++A + + +
Sbjct: 1022 KVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRK---LEGDLKLAQ--ESIMDIE 1076
Query: 114 EEKEVTEERLKAEQESFEKKIRQLEEQNELII---KEREALQLQYRECQELLSL------ 164
EK+ +E+LK ++ ++E++ L I K+ + LQ + E +E +
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 165 ----YQKYLSEQQEKLTMSLSELGAARMQEQQVS-SRKSTLQCSSVELDGSYL------- 212
+ LS + E+++ L E G A + +++ R++ Q +L+ + L
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 213 --------SIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKI 262
S+A QR K ++ SE + + + T+ K +L+K+
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKM 1254
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.4 bits (106), Expect = 1e-04
Identities = 36/150 (24%), Positives = 77/150 (51%), Gaps = 10/150 (6%)
Query: 50 ADVKLKTSRVTDASISMES-LKGTGDSVDEQNSCRGEI--KSASLKDLCLEDKRRIANLI 106
AD + + ++ I +E+ +K + +++ E+ K L+D C E K+ I +L
Sbjct: 905 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 964
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
LA+V +EK TE ++K + +++ L+E + KE++ALQ +++ + L +
Sbjct: 965 LTLAKVEKEKHATENKVK----NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1020
Query: 167 ---KYLSEQQEKLTMSLSELGAARMQEQQV 193
L++ + KL + +L + QE+++
Sbjct: 1021 DKVNTLTKAKIKLEQQVDDLEGSLEQEKKL 1050
Score = 41.2 bits (95), Expect = 0.003
Identities = 81/389 (20%), Positives = 153/389 (39%), Gaps = 57/389 (14%)
Query: 40 RSRHKLMSPKADVKLK-------TSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLK 92
R + KL K+++K++ V+ A ++E + T + + + E + +
Sbjct: 1218 RVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIN 1277
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKI----RQLEEQNELIIKER 148
DL + + R+ E +R +EKE +L +++F ++I RQLEE+ +
Sbjct: 1278 DLTAQ-RGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 149 EALQLQYRECQELLSLYQKYLSEQQEKLTMSLS-------------ELGAARMQEQQVSS 195
ALQ +C L Y++ E + +L +LS E A + E+ +
Sbjct: 1337 HALQSSRHDCDLLREQYEEE-QESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEA 1395
Query: 196 RKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHP 255
+K Q + A+ + +TKQR ++ V+D ++ + L
Sbjct: 1396 KKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVED----LMLDVERTNAACAALDKK 1451
Query: 256 KDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRV 315
+ + DKI +E CE E + E KE L ++ + A +
Sbjct: 1452 QRNFDKILAEWKQ-KCE----------ETHAELEASQKEARSL---GTELFKIKNAYEES 1497
Query: 316 HDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKM 375
D T + ++ E + GG + +E +KKQ+ + +K
Sbjct: 1498 LDQLET-LKRENKNLQQEISDLTE----QIAEGGKRIHELEKIKKQVEQ--------EKC 1544
Query: 376 ELEIEKERLQHLLAQQETKLLLKQQQLHQ 404
EL+ E + L +E K+L Q +L+Q
Sbjct: 1545 ELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Score = 37.0 bits (84), Expect = 0.049
Identities = 42/177 (23%), Positives = 86/177 (48%), Gaps = 18/177 (10%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYR-ECQELLSLY 165
KE+A + EE + ++K E E K ++LEE+ ++KE+ LQLQ + E + L
Sbjct: 853 KEMATMKEEFQ----KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAE 908
Query: 166 QK--YLSEQQEKLTMSLSELGAARMQEQQVSS------RKSTLQCSSV--ELDGSYLSIA 215
++ L + + +L + E+ E+++++ RK +CS + ++D L++A
Sbjct: 909 ERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA 968
Query: 216 R-PQTYYQTKQRPKSAVQDSAS-ESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCN 270
+ + + T+ + K+ ++ A + IA K + H + LD + +E N
Sbjct: 969 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAH-QQTLDDLQAEEDKVN 1024
Score = 35.8 bits (81), Expect = 0.11
Identities = 78/405 (19%), Positives = 160/405 (39%), Gaps = 67/405 (16%)
Query: 20 FSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISM-ESLKGTGDSVDE 78
+ +E++S + ++ N + D +T + +A + + L+ + V+
Sbjct: 1353 YEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEA 1412
Query: 79 QNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLE 138
N+ K ASL+ + K+R+ N +++L E L +Q +F+K + + +
Sbjct: 1413 VNA-----KCASLE----KTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463
Query: 139 EQNELIIKEREALQLQYREC-QELLSLYQKY---------LSEQQEKLTMSLSEL----- 183
++ E E EA Q + R EL + Y L + + L +S+L
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523
Query: 184 -GAARMQE-----QQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASE 237
G R+ E +QV K LQ + L+ + S+ + Q + V+ S +
Sbjct: 1524 EGGKRIHELEKIKKQVEQEKCELQAA---LEEAEASLEHEEGKILRIQLELNQVK-SEVD 1579
Query: 238 SLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECPH 297
IA ++ + + +H + + S +T + E R A+ +K + +L+ E
Sbjct: 1580 RKIAEKDEEIDQLKRNH----IRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEME--- 1632
Query: 298 LKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIET 357
+ +H M + + + + + + +H AL+ E
Sbjct: 1633 -----------------IQLNHANRMAAEALRNYRNTQGILK---DTQIHLDDALRSQED 1672
Query: 358 LKKQISEDRKQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQL 402
LK+Q++ ++ +LQ E E L+ L Q E + +Q+L
Sbjct: 1673 LKEQLAMVERRANLLQ-----AEIEELRATLEQTERSRKIAEQEL 1712
Score = 33.1 bits (74), Expect = 0.71
Identities = 47/238 (19%), Positives = 101/238 (42%), Gaps = 35/238 (14%)
Query: 55 KTSRVTDASISMES-LKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVS 113
K + +T A I +E + S++++ R +++ A K LE ++A + + +
Sbjct: 1022 KVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRK---LEGDLKLAQ--ESIMDIE 1076
Query: 114 EEKEVTEERLKAEQESFEKKIRQLEEQNELII---KEREALQLQYRECQELLSL------ 164
EK+ +E+LK ++ ++E++ L I K+ + LQ + E +E +
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 165 ----YQKYLSEQQEKLTMSLSELGAARMQEQQVS-SRKSTLQCSSVELDGSYL------- 212
+ LS + E+++ L E G A + +++ R++ Q +L+ + L
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 213 --------SIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKI 262
S+A QR K ++ SE + + + T+ K +L+K+
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKM 1254
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 31/179 (17%)
Query: 74 DSVDEQNSCRGEIKSASLKDL-----CLEDKRRIANLIKELARVSE-EKEVTEERLKAEQ 127
D + Q+ +G IK +DL LEDKR KE ++ E E E + K +
Sbjct: 444 DRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKD 503
Query: 128 ESFEKKIRQLEEQNELIIKEREALQLQ-------YRECQELLSLYQKYLSEQQEKLTMSL 180
++ ++ R+LEE+NE + E + Q Y Q+++ K ++ Q+E L
Sbjct: 504 KTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQ 563
Query: 181 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESL 239
++L A +E+ YL + Y R +A QD +++L
Sbjct: 564 AQLDKALQKEKH------------------YLQTTITKEAYDALSRKSAACQDDLTQAL 604
Score = 34.3 bits (77), Expect = 0.32
Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 20/156 (12%)
Query: 104 NLIK----ELARVSEEKE-VTEERLKAE------QESFEKKIRQLEEQNELIIKEREALQ 152
NL+K EL VSE+K + ++ +K E +E I + ++ ++ + LQ
Sbjct: 182 NLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQELQ 241
Query: 153 LQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYL 212
L++ E Q+L K+L E+ E L +L + + QC + EL+
Sbjct: 242 LEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELE---- 297
Query: 213 SIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLK 248
T + KQ + A ++ + NSL+
Sbjct: 298 -----MTVKEAKQDKSKEAECKALQAEVQKLKNSLE 328
Score = 30.0 bits (66), Expect = 6.1
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQN------ELIIKEREALQLQYRECQE 160
K L E + E++L Q S KK ++LE+Q E+ +KE + + + EC+
Sbjct: 256 KFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKA 315
Query: 161 LLSLYQKYLSEQQE-KLTMSLSELGAARMQEQ 191
L + QK + +E K L+ AA+ +E+
Sbjct: 316 LQAEVQKLKNSLEEAKQQERLAAQQAAQCKEE 347
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 31/179 (17%)
Query: 74 DSVDEQNSCRGEIKSASLKDL-----CLEDKRRIANLIKELARVSE-EKEVTEERLKAEQ 127
D + Q+ +G IK +DL LEDKR KE ++ E E E + K +
Sbjct: 589 DRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKD 648
Query: 128 ESFEKKIRQLEEQNELIIKEREALQLQ-------YRECQELLSLYQKYLSEQQEKLTMSL 180
++ ++ R+LEE+NE + E + Q Y Q+++ K ++ Q+E L
Sbjct: 649 KTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQ 708
Query: 181 SELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESL 239
++L A +E+ YL + Y R +A QD +++L
Sbjct: 709 AQLDKALQKEKH------------------YLQTTITKEAYDALSRKSAACQDDLTQAL 749
Score = 34.3 bits (77), Expect = 0.32
Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 20/156 (12%)
Query: 104 NLIK----ELARVSEEKE-VTEERLKAE------QESFEKKIRQLEEQNELIIKEREALQ 152
NL+K EL VSE+K + ++ +K E +E I + ++ ++ + LQ
Sbjct: 327 NLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCRLQELQ 386
Query: 153 LQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYL 212
L++ E Q+L K+L E+ E L +L + + QC + EL+
Sbjct: 387 LEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELE---- 442
Query: 213 SIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLK 248
T + KQ + A ++ + NSL+
Sbjct: 443 -----MTVKEAKQDKSKEAECKALQAEVQKLKNSLE 473
Score = 30.0 bits (66), Expect = 6.1
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 7/92 (7%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQN------ELIIKEREALQLQYRECQE 160
K L E + E++L Q S KK ++LE+Q E+ +KE + + + EC+
Sbjct: 401 KFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKA 460
Query: 161 LLSLYQKYLSEQQE-KLTMSLSELGAARMQEQ 191
L + QK + +E K L+ AA+ +E+
Sbjct: 461 LQAEVQKLKNSLEEAKQQERLAAQQAAQCKEE 492
>gi|18426913 drebrin 1 isoform b [Homo sapiens]
Length = 651
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 28/204 (13%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
+EL + E K+ +ERL+ EQE E++ RQ +E+ E +ERE ++R Q+ L
Sbjct: 190 EELRKEEERKKALDERLRFEQERMEQE-RQEQEERERRYREREQQIEEHRRKQQTLE--- 245
Query: 167 KYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIA--RPQTYYQTK 224
+E+ ++ S G R +E++ +KS S VE + ++ P+ +++ +
Sbjct: 246 ---AEEAKRRLKEQSIFGDHRDEEEETHMKKSE---SEVEEAAAIIAQRPDNPREFFKQQ 299
Query: 225 QRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDK------IPSETTTCNCESPGRKP 278
+R SA SA + N H P LD P T + + S P
Sbjct: 300 ERVASA---SAGSCDVPSPFN-------HRPGSHLDSHRRMAPTPIPTRSPSDSSTASTP 349
Query: 279 AVPTEKMPQEELHMKECPHLKPTP 302
+ +E+ + P L P P
Sbjct: 350 VAEQIERALDEVTSSQPPPLPPPP 373
>gi|18426915 drebrin 1 isoform a [Homo sapiens]
Length = 649
Score = 45.1 bits (105), Expect = 2e-04
Identities = 51/204 (25%), Positives = 88/204 (43%), Gaps = 28/204 (13%)
Query: 107 KELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQ 166
+EL + E K+ +ERL+ EQE E++ RQ +E+ E +ERE ++R Q+ L
Sbjct: 188 EELRKEEERKKALDERLRFEQERMEQE-RQEQEERERRYREREQQIEEHRRKQQTLE--- 243
Query: 167 KYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIA--RPQTYYQTK 224
+E+ ++ S G R +E++ +KS S VE + ++ P+ +++ +
Sbjct: 244 ---AEEAKRRLKEQSIFGDHRDEEEETHMKKSE---SEVEEAAAIIAQRPDNPREFFKQQ 297
Query: 225 QRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDK------IPSETTTCNCESPGRKP 278
+R SA SA + N H P LD P T + + S P
Sbjct: 298 ERVASA---SAGSCDVPSPFN-------HRPGSHLDSHRRMAPTPIPTRSPSDSSTASTP 347
Query: 279 AVPTEKMPQEELHMKECPHLKPTP 302
+ +E+ + P L P P
Sbjct: 348 VAEQIERALDEVTSSQPPPLPPPP 371
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 44.3 bits (103), Expect = 3e-04
Identities = 48/176 (27%), Positives = 84/176 (47%), Gaps = 30/176 (17%)
Query: 20 FSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQ 79
F EE+S+ G V + ++M + D+ L+ V + +ES K GD VD
Sbjct: 443 FRVEEESIT--KGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGD-VDMS 499
Query: 80 NSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVT--EERLKAEQESFEKKIRQL 137
S EI S L++K E+ R ++E+T +E A +E+ +K+I+ L
Sbjct: 500 LSLLQEISS-------LQEK-------LEVTRTDHQREITSLKEHFGAREETHQKEIKAL 545
Query: 138 EEQNELIIKEREALQLQY----RECQELLSLYQKYL-----SEQQ--EKLTMSLSE 182
E + KE E+L+ + +E ++++L++ L S QQ E+L +S S+
Sbjct: 546 YTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSK 601
Score = 35.8 bits (81), Expect = 0.11
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 17/117 (14%)
Query: 67 ESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSE-----EKEVTEE 121
E +K +GD+ + E++ LK+ R + L +L + +E +K + +
Sbjct: 886 EIMKMSGDNSSQLTKMNDELR---LKE------RDVEELQLKLTKANENASFLQKSIEDM 936
Query: 122 RLKAEQESFEKKIRQLEEQNELIIKEREA---LQLQYRECQELLSLYQKYLSEQQEK 175
+KAEQ E + EE+ EL K + ++ + +CQEL + Y++ SE + K
Sbjct: 937 TVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTK 993
Score = 35.0 bits (79), Expect = 0.19
Identities = 41/221 (18%), Positives = 88/221 (39%), Gaps = 26/221 (11%)
Query: 67 ESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAE 126
E G ++E + K+A + ++ ++ E E+ + T +L+ E
Sbjct: 1017 EENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNE 1076
Query: 127 QESFE----KKIRQLEEQNELIIKEREALQLQYRECQEL---LSLYQKYLSEQQEKLTMS 179
++ + K + +L + EL+ E + ++ +E + L + + LS QE+
Sbjct: 1077 LDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKL 1136
Query: 180 LSELGAARMQ---EQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSAS 236
ELG +R + Q++ +S L +E+ K+R ++D+
Sbjct: 1137 AEELGRSRDEVTSHQKLEEERSVLNNQLLEM----------------KKRESKFIKDADE 1180
Query: 237 ESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRK 277
E ++ S+ L +L+K+ +E T E+ K
Sbjct: 1181 EKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAK 1221
Score = 34.3 bits (77), Expect = 0.32
Identities = 41/210 (19%), Positives = 80/210 (38%), Gaps = 14/210 (6%)
Query: 65 SMESLKGTGDSVDEQNSCR----------GEIKSASLKDL---CLEDKRRIANLIKELAR 111
S+E+++ D ++Q+ EIK L+ L C E + I N +L +
Sbjct: 663 SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQL-K 721
Query: 112 VSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSE 171
+EEK + + L+ + ++++L +Q E K+ + L+++ S + L
Sbjct: 722 ATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQG 781
Query: 172 QQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAV 231
++ KLT L ++ + L+ E +S+ R K K
Sbjct: 782 RELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQ 841
Query: 232 QDSASESLIAFRNNSLKPVTLHHPKDDLDK 261
+ S L R N KD+ ++
Sbjct: 842 FNMLSSDLEKLRENLADMEAKFREKDEREE 871
Score = 33.1 bits (74), Expect = 0.71
Identities = 30/174 (17%), Positives = 78/174 (44%), Gaps = 5/174 (2%)
Query: 33 ISAEGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLK 92
+ E N S K S +++ + ++T+ ++ + ++++++ E K A
Sbjct: 761 LEIEKNAESS-KASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKE-KFAEAS 818
Query: 93 DLCLEDKRRIANLIKELARVSEEKEVTE---ERLKAEQESFEKKIRQLEEQNELIIKERE 149
+ + +R + + +L + E+ + E+L+ E K R+ +E+ E +IK +E
Sbjct: 819 EEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKE 878
Query: 150 ALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCS 203
L+ E ++ L++ ++L + ++ +++ + + S LQ S
Sbjct: 879 KLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKS 932
Score = 30.0 bits (66), Expect = 6.1
Identities = 40/213 (18%), Positives = 90/213 (42%), Gaps = 23/213 (10%)
Query: 65 SMESLKGTGDSVDEQNSCRGEIKSA--SLKDLCLEDKRRIANLIKELARVSEE-----KE 117
++E L + + + +N E + +LK + ++++ L +E +++EE E
Sbjct: 1087 NVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDE 1146
Query: 118 VTE-ERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKL 176
VT ++L+ E+ ++ +++++ IK+ + + ++ + S + EKL
Sbjct: 1147 VTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKL 1206
Query: 177 TMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSA------ 230
++ L + + S TL+ V+L+ L + + + +R S+
Sbjct: 1207 RNEVTVLRGENASAKSLHSVVQTLESDKVKLE---LKVKNLELQLKENKRQLSSSSGNTD 1263
Query: 231 ----VQDSASESLIAFRNNSLKPVTLHHPKDDL 259
+ A ES I F N+ + V L DL
Sbjct: 1264 TQADEDERAQESQIDFLNSVI--VDLQRKNQDL 1294
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 43.9 bits (102), Expect = 4e-04
Identities = 83/371 (22%), Positives = 161/371 (43%), Gaps = 31/371 (8%)
Query: 42 RHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRR 101
+ LM+ + VK K S+V+D SLK + +++N +G+ L+ C E K +
Sbjct: 848 KEALMTELSTVKDKLSKVSD------SLKNSKSEFEKENQ-KGKAAILDLEKTCKELKHQ 900
Query: 102 IANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQEL 161
+ ++ + E+KE+ ++ L+ E+E+ + +L E +I+ + L+ +E Q+L
Sbjct: 901 LQVQMENTLK--EQKEL-KKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957
Query: 162 LSLYQ--KYLSEQQEKLTMSL-SELGAARMQEQQVSSR-KSTLQCSSVELDGSYLSIARP 217
K SEQ++K +L EL A +Q+ ++ ++ + L ++ EL I+
Sbjct: 958 QGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVL 1017
Query: 218 QTYYQTKQRPKSAVQDS--ASESLIAFRNNSLKPV--TLHHPKDDLDKIPSETTTCN--- 270
Q Y+ Q +Q ES + LK V L ++DL ++ N
Sbjct: 1018 QNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLI 1077
Query: 271 CESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKT 330
E K + + +E+ + C L+ + L + + + K
Sbjct: 1078 QELKTAKATLEQDSAKKEQQLQERCKALQDIQKE---KSLKEKELVNEKSKLAEIEEIKC 1134
Query: 331 HPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLMLQKMELEIEKERLQHLLAQ 390
E +L+ H +++ I LK D KQ L+ QK+EL+ + + L+ + Q
Sbjct: 1135 RQEK-EITKLNEELKSHKLESIKEITNLK-----DAKQLLIQQKLELQGKADSLKAAVEQ 1188
Query: 391 QE-TKLLLKQQ 400
++ + +LK Q
Sbjct: 1189 EKRNQQILKDQ 1199
Score = 34.3 bits (77), Expect = 0.32
Identities = 64/340 (18%), Positives = 135/340 (39%), Gaps = 42/340 (12%)
Query: 77 DEQNSCR--GEIKSASLKDLCLEDKRRIANLIKELARVS--EEKEVTEERLKAEQESFEK 132
DE+ S R E K L + ++ I +L EL + E+ V ++ L Q +
Sbjct: 180 DEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDN 239
Query: 133 KIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQ 192
+ E ++E + E + LQ QY + +S + L++ +++ + + EL + +
Sbjct: 240 MTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNE 299
Query: 193 VSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTL 252
++ + TL + ++ + Y + ++ +E ++ +N TL
Sbjct: 300 LTQKNQTLTENLLKKEQDYTKL-----------------EEKHNEESVSKKNIQ---ATL 339
Query: 253 HHPKDDLDKIPS-----ETTTCNCESPGRKPAVPTEKMPQEELHMK-ECPHLKPTPSQCC 306
H D ++ S ET+ + T+K+ +E ++ + HLK Q
Sbjct: 340 HQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQ 399
Query: 307 GHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDR 366
R + H + + + H + R L G L+ L + D+
Sbjct: 400 QQR----EEKEQHGLQLQSEINQLHSKLLETER----QLGEAHGRLKEQRQLSSEKLMDK 451
Query: 367 KQQLMLQKMELEIEKERLQHLLAQQETKLLLKQQQLHQSR 406
+QQ+ +L+++ RL+ L ++ T Q QL +++
Sbjct: 452 EQQVA----DLQLKLSRLEEQLKEKVTNSTELQHQLDKTK 487
Score = 32.3 bits (72), Expect = 1.2
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 26/173 (15%)
Query: 39 VRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASL--KDL-C 95
V+ KL S ++ K +T+ + E + + S + A+L KDL C
Sbjct: 287 VQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDC 346
Query: 96 LEDKRRIANLIKELARV----SEEKEVTEERLKAEQESFEKK-------IRQLEEQNELI 144
+ + R++ L R+ SE+ E T+ +LK E E K +QL++Q E
Sbjct: 347 QQLQSRLSASETSLHRIHVELSEKGEATQ-KLKEELSEVETKYQHLKAEFKQLQQQRE-- 403
Query: 145 IKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRK 197
KE+ LQLQ E+ L+ K L +++ L E +++Q+SS K
Sbjct: 404 EKEQHGLQLQ----SEINQLHSKLLETERQ-----LGEAHGRLKEQRQLSSEK 447
Score = 32.3 bits (72), Expect = 1.2
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 14/122 (11%)
Query: 92 KDLCLEDKRRIANLIKEL-ARVSEEK---EVTEERLKAEQESFEKKIRQLEEQNELIIKE 147
K L ++ K + L A V +EK ++ ++++K E+E +K+ + E + IKE
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKE 1224
Query: 148 REALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVEL 207
+E ++ E + L++ L+E LG + + Q R S L+ + +L
Sbjct: 1225 KEVGMKKHEENEAKLTMQITALNE----------NLGTVKKEWQSSQRRVSELEKQTDDL 1274
Query: 208 DG 209
G
Sbjct: 1275 RG 1276
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 43.9 bits (102), Expect = 4e-04
Identities = 40/181 (22%), Positives = 88/181 (48%), Gaps = 24/181 (13%)
Query: 55 KTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSE 114
+T + +++E + + EQ + E ++A+LK+ E +R + N EL ++ E
Sbjct: 411 RTQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKE 470
Query: 115 E---------------KEVTEERLKAEQES------FEKKIRQLEEQNELII-KEREALQ 152
E +EV ++R + +Q++ ++K + L E+ E+++ KE+E LQ
Sbjct: 471 EWSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQ 530
Query: 153 LQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVELDGSYL 212
L+ LL ++Q L + E L +E A +++ + + LQ ++ ++ S++
Sbjct: 531 LERGHNSALLQIHQ--LQAELEALRTLKAEEAAVVAEQEDLLRLRGPLQAEALSVNESHV 588
Query: 213 S 213
+
Sbjct: 589 T 589
Score = 37.7 bits (86), Expect = 0.029
Identities = 48/195 (24%), Positives = 86/195 (44%), Gaps = 16/195 (8%)
Query: 36 EGNVRSRHKLMSPKADVKLKTSRVT-DASISMESLKGTGDSVDEQNSCRGEIKS-ASLKD 93
E + +R + +S + + +++++ D S +E L+ +++EQ K+ A K
Sbjct: 199 EQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKI 258
Query: 94 LCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQL 153
LE K + EL + ++ + +++ AE + E I L+E+ + K E
Sbjct: 259 TALEQKEQ------ELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLS 312
Query: 154 QYRECQELLSLYQKYLSEQ------QEKLTMSLSELGAARMQEQQVSSRKSTLQCSSVEL 207
QELL +K L+EQ Q+ L S+ A E +V + TLQ S +L
Sbjct: 313 GEEHVQELLK--EKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQL 370
Query: 208 DGSYLSIARPQTYYQ 222
S +A +T Q
Sbjct: 371 QQSKGIVAAQETQIQ 385
Score = 32.0 bits (71), Expect = 1.6
Identities = 26/115 (22%), Positives = 50/115 (43%), Gaps = 11/115 (9%)
Query: 96 LEDKRRIANLIKELARVSEEKEVTEERLKAEQES-------FEKKIRQLEE----QNELI 144
L + + L+KE + E T ++L A + S E ++R+LE+ E +
Sbjct: 311 LSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQL 370
Query: 145 IKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKST 199
+ + + Q + QEL + Q+ QQ+ L + L + E Q+ + + T
Sbjct: 371 QQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERT 425
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 43.9 bits (102), Expect = 4e-04
Identities = 89/403 (22%), Positives = 151/403 (37%), Gaps = 59/403 (14%)
Query: 33 ISAEGNVRSR-HKL-MSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSAS 90
+SA+ + R H+L M A + K+S + + + ME L + DS+++ NS G
Sbjct: 189 LSAKEEIAQRCHELDMQVAALQEEKSSLLAENQVLMERLNQS-DSIEDPNSPAG------ 241
Query: 91 LKDLCLEDKRRIANLIKELARVSEEK---EVTEERLKAEQESFEKKIRQLEEQNELIIKE 147
RR L +L ++ EE E ++ + E EK+I +L +QN+ +
Sbjct: 242 ---------RRHLQLQTQLEQLQEETFRLEAAKDDYRIRCEELEKEISELRQQNDELTTL 292
Query: 148 REALQLQYRECQELLSLYQKY--LSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQCSSV 205
+ Q E L K L Q E L +LG R Q + + + + ++V
Sbjct: 293 ADEAQSLKDEIDVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTV 352
Query: 206 ELDGSYLSIARPQTYYQTKQRPKSAVQDSASESLIAFRNNSLKPVTLHHPKDDLDKIPSE 265
L+ ++ +T +R +Q+ SE + K+ +D + E
Sbjct: 353 SLEEELRKANAARSQLETYKRQVVELQNRLSEE---SKKADKLDFEYKRLKEKVDSLQKE 409
Query: 266 TTTCNCESPGRKPAVPTEKMPQEELHMKECPHLKPTPSQCCGHRLAADRVHDSHPTNMTP 325
E K + + Q + L P SQ LAA+ V TP
Sbjct: 410 KDRLRTERDSLKETIEELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIV--------TP 461
Query: 326 QHPKTHPESCSYCRLSWASLVHGGGALQPIETLKKQISEDRKQQLM--------LQKMEL 377
+ R L H L+ L ++ S++ K L+ L+K EL
Sbjct: 462 E-----------IREKLIRLQHENKMLK----LNQEGSDNEKIALLQSLLDDANLRKNEL 506
Query: 378 EIEKERLQHLL--AQQETKLLLKQQQLHQSRLDYNCLLKSNCD 418
E E + L Q + + L K Q S+ + + LLK +
Sbjct: 507 ETENRLVNQRLLEVQSQVEELQKSLQDQGSKAEDSVLLKKKLE 549
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 43.5 bits (101), Expect = 5e-04
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 22/171 (12%)
Query: 41 SRHKLMSPKADV-----KLKTSRVTDASISMESLKG----TGDSVDEQNSCRGEIKSASL 91
SRH+ M +L T +V A + +LKG T D++ E+ G ++
Sbjct: 560 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL--- 616
Query: 92 KDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREAL 151
D R+ + IKE+ ++ E E + +Q S E++IRQ E +N L+ ++ E
Sbjct: 617 ------DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDA 670
Query: 152 QLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQC 202
+ + + ++++++ L +E L L E M+E K LQC
Sbjct: 671 RKEGDNKEIVINIHRDCLENGKEDL---LEERNKELMKEYNYLKEK-LLQC 717
Score = 37.0 bits (84), Expect = 0.049
Identities = 32/126 (25%), Positives = 63/126 (50%), Gaps = 14/126 (11%)
Query: 77 DEQNSCRGEIKSASLK-DLCLED-KRRIANLIKELARVSEE-------KEVTEERLKAEQ 127
+E SC G++ + LK D+ + K++ +L+ E VS E EV + L +
Sbjct: 830 NEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS-M 888
Query: 128 ESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSL--YQKYLSEQQEKLTMSLSELGA 185
+ ++K +LE+ +++ E E L L+ ++++ L Q+Y SE E+ + +L
Sbjct: 889 RNVQEKCEKLEKDKKML--EEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEE 946
Query: 186 ARMQEQ 191
+Q+Q
Sbjct: 947 IHLQKQ 952
Score = 33.9 bits (76), Expect = 0.42
Identities = 32/114 (28%), Positives = 59/114 (51%), Gaps = 15/114 (13%)
Query: 75 SVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEK-K 133
S+ +QNS I+ L++L LE R++ + KE + KE+ + ++ E K
Sbjct: 642 SIGKQNSLEERIRQQELENLLLE--RQLEDARKE----GDNKEIV---INIHRDCLENGK 692
Query: 134 IRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKL-----TMSLSE 182
LEE+N+ ++KE L+ + +C++ + + + E QE+L T S+SE
Sbjct: 693 EDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISE 746
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 43.5 bits (101), Expect = 5e-04
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 22/171 (12%)
Query: 41 SRHKLMSPKADV-----KLKTSRVTDASISMESLKG----TGDSVDEQNSCRGEIKSASL 91
SRH+ M +L T +V A + +LKG T D++ E+ G ++
Sbjct: 453 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQL--- 509
Query: 92 KDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREAL 151
D R+ + IKE+ ++ E E + +Q S E++IRQ E +N L+ ++ E
Sbjct: 510 ------DLRQAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDA 563
Query: 152 QLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQVSSRKSTLQC 202
+ + + ++++++ L +E L L E M+E K LQC
Sbjct: 564 RKEGDNKEIVINIHRDCLENGKEDL---LEERNKELMKEYNYLKEK-LLQC 610
Score = 40.0 bits (92), Expect = 0.006
Identities = 60/290 (20%), Positives = 124/290 (42%), Gaps = 42/290 (14%)
Query: 77 DEQNSCRGEIKSASLK-DLCLED-KRRIANLIKELARVSEE-------KEVTEERLKAEQ 127
+E SC G++ + LK D+ + K++ +L+ E VS E EV + L +
Sbjct: 723 NEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLS-M 781
Query: 128 ESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSL--YQKYLSEQQEKLTMSLSELGA 185
+ ++K +LE+ +++ E E L L+ ++++ L Q+Y SE E+ + +L
Sbjct: 782 RNVQEKCEKLEKDKKML--EEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEE 839
Query: 186 ARMQ---------EQQVSSRKSTLQCSSVELDGSYLSIARPQTYYQTKQRPKSAVQDSAS 236
+Q EQ ++L+ + L ++ +T Y+ +++ +
Sbjct: 840 IHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEEVTTELEEFKEAFA 899
Query: 237 ESLIAFRNNSLKPVTLHHPKDDLDKIPSETTTCNCESPGRKPAVPTEKMPQEELHMKECP 296
++ A NNS+ + K KI +T K + E+M E + P
Sbjct: 900 GAVKA--NNSMSKKLMKSDK----KIAVIST---------KLFMEKERM---EYFLSTLP 941
Query: 297 HLKPTPSQCCGHRLAADRVHDSHPTNMTPQHPKTHPESCSYCRLSWASLV 346
++P P C L + ++ + M + P ++P++ + C+ S L+
Sbjct: 942 -MRPDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELL 990
Score = 33.9 bits (76), Expect = 0.42
Identities = 32/114 (28%), Positives = 59/114 (51%), Gaps = 15/114 (13%)
Query: 75 SVDEQNSCRGEIKSASLKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEK-K 133
S+ +QNS I+ L++L LE R++ + KE + KE+ + ++ E K
Sbjct: 535 SIGKQNSLEERIRQQELENLLLE--RQLEDARKE----GDNKEIV---INIHRDCLENGK 585
Query: 134 IRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKL-----TMSLSE 182
LEE+N+ ++KE L+ + +C++ + + + E QE+L T S+SE
Sbjct: 586 EDLLEERNKELMKEYNYLKEKLLQCEKEKAEREVIVREFQEELVDHLKTFSISE 639
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,110,903
Number of Sequences: 37866
Number of extensions: 1218470
Number of successful extensions: 10069
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 606
Number of HSP's that attempted gapping in prelim test: 6134
Number of HSP's gapped (non-prelim): 3806
length of query: 577
length of database: 18,247,518
effective HSP length: 108
effective length of query: 469
effective length of database: 14,157,990
effective search space: 6640097310
effective search space used: 6640097310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.