Guide to the Human Genome
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Search of human proteins with 54633315

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54633315 deoxynucleotidyltransferase, terminal, interacting
protein 2 [Homo sapiens]
         (756 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54633315 deoxynucleotidyltransferase, terminal, interacting p...  1481   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    78   3e-14
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]    53   9e-07
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            51   3e-06
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    51   3e-06
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                50   1e-05
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 50   1e-05
gi|55956788 nucleolin [Homo sapiens]                                   50   1e-05
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         50   1e-05
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         50   1e-05
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    50   1e-05
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    49   1e-05
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       49   2e-05
gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]    49   2e-05
gi|122891870 melanoma inhibitory activity family, member 3 [Homo...    48   3e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    48   3e-05
gi|154354979 myosin X [Homo sapiens]                                   48   4e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    47   5e-05
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H...    46   1e-04
gi|17975763 myelin transcription factor 1 [Homo sapiens]               45   2e-04
gi|210032580 SET domain containing 1B [Homo sapiens]                   45   2e-04
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       45   2e-04

>gi|54633315 deoxynucleotidyltransferase, terminal, interacting
           protein 2 [Homo sapiens]
          Length = 756

 Score = 1481 bits (3835), Expect = 0.0
 Identities = 756/756 (100%), Positives = 756/756 (100%)

Query: 1   MVVTRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPR 60
           MVVTRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPR
Sbjct: 1   MVVTRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPR 60

Query: 61  TPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVS 120
           TPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVS
Sbjct: 61  TPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVS 120

Query: 121 SVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHT 180
           SVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHT
Sbjct: 121 SVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHT 180

Query: 181 EAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSD 240
           EAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSD
Sbjct: 181 EAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSD 240

Query: 241 TRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLD 300
           TRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLD
Sbjct: 241 TRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLD 300

Query: 301 EDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVM 360
           EDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVM
Sbjct: 301 EDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVM 360

Query: 361 KSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDF 420
           KSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDF
Sbjct: 361 KSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDF 420

Query: 421 ECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTG 480
           ECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTG
Sbjct: 421 ECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTG 480

Query: 481 SLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENED 540
           SLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENED
Sbjct: 481 SLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENED 540

Query: 541 EFSDEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKK 600
           EFSDEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKK
Sbjct: 541 EFSDEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKK 600

Query: 601 NELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKND 660
           NELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKND
Sbjct: 601 NELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKND 660

Query: 661 LKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRIPKKQRKRTIVEELLA 720
           LKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRIPKKQRKRTIVEELLA
Sbjct: 661 LKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRIPKKQRKRTIVEELLA 720

Query: 721 DSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN 756
           DSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN
Sbjct: 721 DSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN 756


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 110/570 (19%), Positives = 220/570 (38%), Gaps = 43/570 (7%)

Query: 6    SARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKAR 65
            S+ +K+    + ++SS   S + +      +SS  SD+  ++ S  +   S    +  + 
Sbjct: 619  SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678

Query: 66   KRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKK 125
                 +  S    +  S++   S   S+ S S+  D+              S  S+    
Sbjct: 679  SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS--------------SDSSNSNSS 724

Query: 126  PKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISD 185
               +      ++   S   S  S  S     ++ +  +  S +   +D S  S +   SD
Sbjct: 725  DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784

Query: 186  AETSS--SDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQ 243
            +  SS  SD S S  ++  + S      + +   DS               NS DS    
Sbjct: 785  SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS--------------NSSDSSNSS 830

Query: 244  TSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDA 303
             S   + S S+ +  +  ++  D D S+RS  +  +    ++  S      +  D +E +
Sbjct: 831  DSSDSSNS-SDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889

Query: 304  NGI--TDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMK 361
            N    +D     +  SS   N S+  D+S     S+  ++  N N+    ++ +S     
Sbjct: 890  NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949

Query: 362  SLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFE 421
            S   + ++      N++  S   +SD +   +   S D  +S+  S S D ++  +    
Sbjct: 950  SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1009

Query: 422  CDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEE--DTLCFVENSGQRESLSGDT 479
             D+   +++ ++S   D+S     SSD S  S++S++ +  D+    ++S   +S     
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSN----SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065

Query: 480  GSLSCDNALFVIDTTPGMSADKNFYLEEEDKA--SEVAIEEEKEEEEDEKSEEDSSDHDE 537
             S S D++     +    S+D +      D +  S+ +   +  +  D     DSS+  +
Sbjct: 1066 SSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125

Query: 538  NED--EFSDEEDFLNSTKAKLLKLTSSSID 565
            + D  + SD  D  NS+ +     +S S D
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155



 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 109/565 (19%), Positives = 215/565 (38%), Gaps = 39/565 (6%)

Query: 4    TRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPK 63
            + S+ +  S  ++ +  S   S ++N      +SS  SD+  ++ES  +   S    +  
Sbjct: 660  SNSSNSSDSSDSSDSSDSSSSSDSSNS----SDSSDSSDSSNSSESSDSSDSSDSDSSDS 715

Query: 64   ARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVR 123
            +    S ++ S    +  S+D   S   S+ S S +               +     S  
Sbjct: 716  SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD------------SSDSSDSSN 763

Query: 124  KKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAI 183
                   +  S + +  + ++S+ S  S     +  ++ +  S   S +  S +S +   
Sbjct: 764  SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 184  SDAETSS--SDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDT 241
            SD+  SS  SD S S  ++  + S        + + DS     N      +  +S  SD+
Sbjct: 824  SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSS----NSSDSSDSSDSSNSSDS 879

Query: 242  RQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKET-KQNCKDLD 300
              +S     S S  +  +  ++D D   S  SS++  + +   + ES   +   N  D  
Sbjct: 880  SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS 939

Query: 301  EDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVM 360
              ++         +  SS   + S   D+S         S+  + ++ S  S+ +S++  
Sbjct: 940  NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999

Query: 361  KSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDF 420
             S +   +       ++N      +SD +   D   S D  +S+  S S D +   N   
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059

Query: 421  ECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTG 480
              D+   + + ++S   D+S      S ES  S +S N  D+    ++S   +S      
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSS-----DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114

Query: 481  SLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENED 540
            S S D++          S+D +   +  D +S+ +   +  +  +     DSSD  ++ D
Sbjct: 1115 SDSSDSS---------NSSDSSDSSDSSD-SSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164

Query: 541  EFSDEEDFLNSTKAKLLKLTSSSID 565
              SD  D  +S+ +     +S S D
Sbjct: 1165 S-SDSSDSSDSSDSSNSSDSSDSSD 1188



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 110/570 (19%), Positives = 216/570 (37%), Gaps = 38/570 (6%)

Query: 6    SARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKAR 65
            S+ + +S   +S++S    S +++   +    S+ S   + +   +    S      K+ 
Sbjct: 566  SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625

Query: 66   KRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKK 125
              KS +  S       S+D  +S++  N   S+  ++    +       +     S    
Sbjct: 626  SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS----SNSSDSSDSSDSSDSSSSS 681

Query: 126  PKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISD 185
                 +  S + +  + +ES  S  S     ++ +  +  + + S +  S +S   + S 
Sbjct: 682  DSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741

Query: 186  AETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTS 245
              + SSD S S  ++  + S      + +          N      +  +S+ SD+  +S
Sbjct: 742  DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801

Query: 246  HLQARSLSEINKPNFYNNDFDDDFSHRS-SENILTVHEQANVESLKETKQNCKDLDEDAN 304
                 S S  +     ++  D D S+ S S N     + +N     ++  +    D D++
Sbjct: 802  DSSNSSDSSDS-----SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856

Query: 305  GITDEGKEINEK-SSQLKNLSELQDTSLQQLVSQRHSTPQNKNAV---SVHSNLNSEAVM 360
              +D     +   SS   N S+  D+S     S    +  + N+    S  S+ +S++  
Sbjct: 857  NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916

Query: 361  KSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEE---ESTVISVSEDMNSEGN 417
             S +   +       N+N      +SD +   D   S D     +S+  S S D NS  +
Sbjct: 917  SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
             D          + N+S   D+S      S +S  S +S N  D+    ++S   +S + 
Sbjct: 977  SD----------SSNSSDSSDSS-----DSSDSSDSSDSSNSSDS---SDSSDSSDSSNS 1018

Query: 478  DTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDE 537
               S S D++     +    S+D +   +  D +S+ +   +  +  D     DSSD  +
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD-SSDSSNSSDSSDSSDSSDSSDSSDSSD 1077

Query: 538  NED--EFSDEEDFLNSTKAKLLKLTSSSID 565
            + D  E SD  D  NS+ +     +S S D
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107



 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 93/544 (17%), Positives = 205/544 (37%), Gaps = 33/544 (6%)

Query: 6    SARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKAR 65
            S+ +  S  ++ +  S   S ++N   ++ +SS  SD+  ++ S  +   S    +  + 
Sbjct: 758  SSDSSNSSDSSDSSDSSDSSDSSNSSDSN-DSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816

Query: 66   KRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKK 125
               S  +      ++ S    +S++  +   S+  D+    + R     +     S    
Sbjct: 817  DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS--DSSNRSDSSNSSDSSDSSDSS 874

Query: 126  PKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISD 185
                 +  S + E  + ++S  S  S     ++ +  +  S + + +D S+ S++   S+
Sbjct: 875  NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934

Query: 186  AETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTS 245
            +  SS+    S  +     S        +   DS     N      +  +S+ SD+  +S
Sbjct: 935  SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS--DSNSSDSSDSSNSSDSSDSSDSS 992

Query: 246  HLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANG 305
                 S S  +  +  ++D  D  +   S N                  N  D  + ++ 
Sbjct: 993  DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN-------------SSDSSNSSDSSDSSDS 1039

Query: 306  ITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQ 365
                    +  SS   N S+  D+S         S+  + ++ S  S+ +SE+   S + 
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSS--------DSSDSSDSSDSSDSSDSSESSDSSDSS 1091

Query: 366  TFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTK 425
              +       +++      +SD +   D   S D  +S+  S S D ++  +     ++ 
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151

Query: 426  LYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCD 485
              + + ++S   D+S      S +S  S +S N  D+    ++S   +S      S S D
Sbjct: 1152 DSSDSSDSSDSSDSS-----DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1206

Query: 486  NALFVIDTTPGMSADKNFYLEEED--KASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFS 543
            ++     +    S+D +   +  D  ++S+ +   +  +  +     DSSD  ++  + +
Sbjct: 1207 SSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSN 1266

Query: 544  DEED 547
            DE D
Sbjct: 1267 DESD 1270



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 71/332 (21%), Positives = 134/332 (40%), Gaps = 31/332 (9%)

Query: 235 NSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQ 294
           +S DSD+  +S+    S S  +  +  N+  D D S   S       + ++ +S   +  
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSS------DSSDSDSSDSSNS 601

Query: 295 NCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNL 354
           +      D++  +D     + KS   K+ S+  D+  +   S  +S+  + N+ S  S+ 
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661

Query: 355 NSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNS 414
           +S +   S +           +++  S   +S+ +   D   S +  ES+  S S D +S
Sbjct: 662 SSNSSDSSDSSD---------SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712

Query: 415 EGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRES 474
             + D        + + N+S   D+S     +S +S  S +S N  D+    ++S   +S
Sbjct: 713 SDSSDSSNSNSSDSDSSNSSDSSDSS-----NSSDSSDSSDSSNSSDSSDSSDSSNSSDS 767

Query: 475 LSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSD 534
                 S S D++          S+D N      D +S+ +   +     D     DSSD
Sbjct: 768 SDSSDSSDSSDSS---------NSSDSNDSSNSSD-SSDSSNSSDSSNSSDSSDSSDSSD 817

Query: 535 HD-ENEDEFSDEEDFLNSTKAKLLKLTSSSID 565
            D  N  + S+  D  +S+ +     +S S D
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 89/539 (16%), Positives = 196/539 (36%), Gaps = 26/539 (4%)

Query: 6    SARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKAR 65
            S  + +S  + S++SS     + +   +  +SS  SD+  +++S  +   S    +  + 
Sbjct: 789  SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSS 848

Query: 66   KRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKK 125
                  + +    +  S   ++S++ ++   S+  D+              +  S+    
Sbjct: 849  DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS--------------NESSNSSDS 894

Query: 126  PKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISD 185
               + + +S + +  + ++S  S  S     +  ++    S   S +  S +S   + S 
Sbjct: 895  SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSS 954

Query: 186  AETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTS 245
              ++SSD S S  ++    S        ++  DS     ++        NS DS     S
Sbjct: 955  DSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS--DSSDSSDSSDSSNSSDSSDSSDS 1012

Query: 246  HLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANG 305
               + S    N  +  N+    D S  S  +  +    ++  S      +  D  + ++ 
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072

Query: 306  ITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQ 365
                    + +SS   + S   D+S         S+  + ++ S  S+ +S++   S + 
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSS-----DSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127

Query: 366  TFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTK 425
              +       ++N      +S+ +   D   S D  +S+  S S D +   N     D+ 
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187

Query: 426  LYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCD 485
              + + ++S   D+S      S +S  S +S +  D+    ++S   +S      S S D
Sbjct: 1188 DSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 1242

Query: 486  NALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSD 544
            ++     +    S+D +    + +  S+   +          S+ DS   D N     D
Sbjct: 1243 SSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 87/421 (20%), Positives = 168/421 (39%), Gaps = 48/421 (11%)

Query: 164 RRSKAKSLTDPS--QESHTEAISDAETSSSDISFSGI----ATRRTRSMQRKLKAQTEKK 217
           + S +K   DP   ++ H E   D +TS S+ + +GI     ++R    Q+    ++++ 
Sbjct: 297 QNSDSKEYYDPEGKEDPHNEVDGD-KTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRV 355

Query: 218 DSKIVPGNEKQIVGTPVNSEDS--DTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSE 275
           +++I   +E   VG    S+D   + +  S        E+ K N    D           
Sbjct: 356 ENRITKESETHAVG---KSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKG 412

Query: 276 NILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLV 335
           N+ T  E  N+E   +  +    +     G        ++ +S   +  +  D S+Q   
Sbjct: 413 NVKTQGEVVNIEGPGQKSEPGNKVGHSNTG--------SDSNSDGYDSYDFDDKSMQG-- 462

Query: 336 SQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG 395
                 P + +  + + + NSE+   S ++  A+      ++  K     SD       G
Sbjct: 463 ----DDPNSSDESNGNDDANSESDNNSSSRGDASYN----SDESKDNGNGSDSK-----G 509

Query: 396 GSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSEN 455
             DD+ +ST  + + D N  GN   + + K  +    +     +S     SSD S  S++
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDS 569

Query: 456 SENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVA 515
             ++ ++    ++S    S S D+ S    N+    D++   S+D +   +  D  S+ +
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD--SSDSSDSSDSSDSKSDSS 627

Query: 516 IEEEKEEEEDEKSEE------DSSDHDENED-----EFSDEEDFLNSTKAKLLKLTSSSI 564
             E    + D KS+       DSSD+ ++ D       SD  D  +S+ +     +S+S 
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 565 D 565
           D
Sbjct: 688 D 688



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 113/589 (19%), Positives = 216/589 (36%), Gaps = 83/589 (14%)

Query: 7   ARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKARK 66
           A  + +I+  + ++   +++  +GI    E+ T +  +        G+ S+I        
Sbjct: 100 ANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQ--------GQVSIIDNA--GAT 149

Query: 67  RKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKP 126
            +S T G+  K T+   +G+  +A  N  V+        V +     +A S  S+  +  
Sbjct: 150 NRSNTNGNTDKNTQ---NGDVGDAGHNEDVA--------VVQEDGPQVAGSNNSTDNEDE 198

Query: 127 KVTPT--KESYTEEIVSEAESHVSGI--SRIVLPTEKTTGARRSKAKSLTDPSQESHTEA 182
            +  +   E  T EI  +  S  +G   + +   T +  G   S      + + E   E 
Sbjct: 199 IIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEG 258

Query: 183 ISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTR 242
             D E   +       ++  ++  + +   + +  DS I   ++ +    P   ED    
Sbjct: 259 SGDDEDEEAGNGKD--SSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDP--- 313

Query: 243 QTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKET-KQNCKDLDE 301
                              +N+ D D + +S EN   + E    + +++T K N ++   
Sbjct: 314 -------------------HNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKR 354

Query: 302 DANGITDEGKEINEKSSQLKNLSELQDTSL--QQLVSQRHSTPQNKNAVSVHSNLNSEAV 359
             N IT E +      SQ K + E++  S   + +  +     + K     H  +  +  
Sbjct: 355 VENRITKESETHAVGKSQDKGI-EIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGN 413

Query: 360 MKSLTQTFATV----------EVGRWNNNKKSPIKASDLTKFGDCG-GSDDEEESTVISV 408
           +K+  +               +VG  N    S     D   F D     DD   S   + 
Sbjct: 414 VKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNG 473

Query: 409 SEDMNSE--------GNVDFECDTKLYTSAPNTSQGKDN----SVLLVLSSDESQQSENS 456
           ++D NSE        G+  +  D        + S+G ++    S     +SD +    N 
Sbjct: 474 NDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNG 533

Query: 457 ENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAI 516
            ++ D      +SG+ +S S D+ S    N+    D++   S+D N    + D +   + 
Sbjct: 534 NDDNDK----SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN-SSSDSDSSDSDSS 588

Query: 517 EEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTSSSID 565
           +    +  D  +  DSSD  ++ D  SD  D  +S K+   K  S S D
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDS-SDSSDSSDS-KSDSSKSESDSSD 635



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 50/235 (21%), Positives = 86/235 (36%), Gaps = 40/235 (17%)

Query: 345 KNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEEST 404
           ++ VSV   LN+   +K         + GR  N +       + +K+ + GG      ST
Sbjct: 39  RSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVGGKSFSTYST 98

Query: 405 VISVSEDMNSEGNVD-FECDT-KLYTSAPNTSQGK----------------DNSVLLVLS 446
           +       N EGN++ +  DT K  T   +   GK                DN+     S
Sbjct: 99  L------ANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGATNRS 152

Query: 447 SDESQQSENSEN--------EEDTLCFVENSGQRESLSGDTGS------LSCDNALFVID 492
           +      +N++N         ED     E+  Q    +  T +       SC N     +
Sbjct: 153 NTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSE 212

Query: 493 TTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
            TP +++ +N   E E   +    E+   +  D     + +D DE+E    DE++
Sbjct: 213 ITPQINSKRNGTKEAE--VTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDE 265


>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
          Length = 1462

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 114/571 (19%), Positives = 222/571 (38%), Gaps = 69/571 (12%)

Query: 21   SGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKA-RKRKSRTTGSLPKGT 79
            S  +S++    ++   S + S +R+ ++S+++ K     R  K+ RK  S+ + + P  T
Sbjct: 523  SHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKT 582

Query: 80   EP--STDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKESYTE 137
            EP  +T  +         V+E+   I          ++ SP  S R KP   P K SY  
Sbjct: 583  EPLRATMAQNENVVVQPVVAENIPVIP---------LSDSPPPS-RWKPGQKPWKPSY-- 630

Query: 138  EIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSSSDISFSG 197
            E + E ++  + +    LP + T      K    +    +    + SD  T S     S 
Sbjct: 631  ERIQEMKAKTTHL----LPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSS 686

Query: 198  IATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINK 257
             ++ R+RS   + ++ +            + +  +   S    +R  S  +    S+ ++
Sbjct: 687  ESSPRSRSRSSRSRSYSRSYT------RSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSR 740

Query: 258  PNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEG---KEIN 314
             + Y +   DD   R+   + +  ++ +V   K +  + K L        D     ++ +
Sbjct: 741  SSSYTSISSDD-GRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYS 799

Query: 315  EKSSQLKNLSELQDTSLQQLVS----------QRHSTPQNKNAVSVHSNLNSE---AVMK 361
            E  S L   S+ + +S+Q   S          +R    Q KN     S    E   +  +
Sbjct: 800  ESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKR 859

Query: 362  SLTQTFA------------TVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVS 409
            +L +  +                 +W++   S    +  +K  D   S D+EE    S S
Sbjct: 860  TLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSK-NDSHPSSDKEEGEATSDS 918

Query: 410  EDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENS 469
            E   SE ++  +  TK   S+ NTS   DN           Q++  S++E        N 
Sbjct: 919  ESEVSEIHIKVKPTTK---SSTNTSLPDDNGAW----KSSKQRTSTSDSEGSCSNSENNR 971

Query: 470  GQ-RESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAI-----EEEKEEE 523
            G+ ++   G   +L  ++   V +   G   DK     +  +A          EEE+EE 
Sbjct: 972  GKPQKHKHGSKENLKREHTKKVKEKLKGKK-DKKHKAPKRKQAFHWQPPLEFGEEEEEEI 1030

Query: 524  EDEKSEEDSSDHDENEDEFSDEEDFLNSTKA 554
            +D++  ++S +   +E+  + +++ L + K+
Sbjct: 1031 DDKQVTQESKEKKVSENNETIKDNILKTEKS 1061



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 81/410 (19%), Positives = 158/410 (38%), Gaps = 57/410 (13%)

Query: 35  PESSTGSDARTTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTDGETSEAESNY 94
           P  S GSD+ + + S +           ++R+RK +    + +  +   +  +SE   N 
Sbjct: 192 PTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNK 251

Query: 95  SV------SEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKESYTEE---------- 138
                   SE  DT      +R +       S+ R+KP V P +     E          
Sbjct: 252 HAMNPKGHSERSDT----NEKRSV-----DSSAKREKPVVRPEEIPPVPENRFLLRRDMP 302

Query: 139 -IVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSSSDISFSG 197
            + +E E  +  ++ IV  +++     +S  K     +   HT   S + + S D   S 
Sbjct: 303 VVTAEPEPKIPDVAPIV--SDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDDSSE 360

Query: 198 IATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINK 257
                   MQR L+A          P  EK   G  ++   S     S    RSLS+ ++
Sbjct: 361 TPPHWKEEMQR-LRAYRP-------PSGEKWSKGDKLSDPCS-----SRWDERSLSQRSR 407

Query: 258 PNFYNNDFDDDFSHRSSENILTVHEQANVESLKETK--QNC---KDLDEDANGITDEGKE 312
              YN  + D  + R S +     ++  V+  K+ K  ++C   K   +    I  + + 
Sbjct: 408 SWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIES 467

Query: 313 INEKSSQLKNLSELQDTSLQQLVSQRHSTPQ--NKNAVSVHSNLNSEA----VMKSLTQT 366
               + ++K+  + + +S    +S  HS+ +  +K+   V S+L   +      KS +Q+
Sbjct: 468 SKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQS 527

Query: 367 FA-----TVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSED 411
           ++     +    + +++ +S  K+   +K G    +      T   +SE+
Sbjct: 528 YSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSEN 577


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 92/503 (18%), Positives = 179/503 (35%), Gaps = 33/503 (6%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T      GS+    ST  S +   ++ G+
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTT-ASTAGSETTTASTAGSETTTASTSGS 1221

Query: 418  -VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLS 476
              +  C T   TS P+++  + N+  ++ S      + + E    +L   E +    + S
Sbjct: 1222 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1281

Query: 477  GDT-GSLSCDNALFVIDTTPGMS 498
            G T  S +  +  FV+     +S
Sbjct: 1282 GATAASTTVSSTTFVLTKATDVS 1304



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 42/193 (21%), Positives = 72/193 (37%), Gaps = 8/193 (4%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDART--TAESQTTGKQSLIPRTPKARKRKSRTTG 73
            +SA  S   + +  G +    S+ GS+  T  TA S+TT   +    T  A    S T  
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1225

Query: 74   SLPKGTEPSTDGETSEAESNYSVSEHHDTI-----LRVTRRRQILIACSPVSSVRKKPKV 128
            +   G+E ST        +   +     TI     L  T         + VS        
Sbjct: 1226 ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATA 1285

Query: 129  TPTKESYTEEIVSEA-ESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAE 187
              T  S T  ++++A +  +  I+   +   +TTG R + + S+T       T + +   
Sbjct: 1286 ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHT 1345

Query: 188  TSSSDISFSGIAT 200
                 ++ SG+ T
Sbjct: 1346 VPGIVLNTSGLGT 1358


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 94/502 (18%), Positives = 176/502 (35%), Gaps = 41/502 (8%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T     G      E+T  S S    SE N
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-----SETTTASTS---GSETN 1214

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
                C T   TS P+++  + N+  ++ S      + + E    +L   E +    + SG
Sbjct: 1215 T--ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASG 1272

Query: 478  DT-GSLSCDNALFVIDTTPGMS 498
             T  S +  +  FV+     +S
Sbjct: 1273 ATAASTTVSSTTFVLTKATDVS 1294



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 94/502 (18%), Positives = 176/502 (35%), Gaps = 41/502 (8%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T     G      E+T  S S    SE N
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-----SETTTASTS---GSETN 1214

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
                C T   TS P+++  + N+  ++ S      + + E    +L   E +    + SG
Sbjct: 1215 T--ACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASG 1272

Query: 478  DT-GSLSCDNALFVIDTTPGMS 498
             T  S +  +  FV+     +S
Sbjct: 1273 ATAASTTVSSTTFVLTKATDVS 1294



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 578  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 637

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 638  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 692

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 693  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 752

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 753  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 805

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 806  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 865

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 866  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 925

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 926  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 985

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 986  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1045

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1046 ITSTEGS 1052



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 94/502 (18%), Positives = 176/502 (35%), Gaps = 41/502 (8%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 836  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 895

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 896  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 954

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 955  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 1014

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 1015 TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1073

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1074 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1133

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1134 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1183

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T     G      E+T  S S    SE N
Sbjct: 1184 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-----SETTTASTS---GSETN 1235

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
                C T   TS P+++  + N+  ++ S      + + E    +L   E +    + SG
Sbjct: 1236 T--ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASG 1293

Query: 478  DT-GSLSCDNALFVIDTTPGMS 498
             T  S +  +  FV+     +S
Sbjct: 1294 ATAASTTVSSTTFVLTKATDVS 1315



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 103/592 (17%), Positives = 203/592 (34%), Gaps = 43/592 (7%)

Query: 1   MVVTRSARAKASIQAASAESSGQKS--FAANGIQAHPESSTGSDAR--TTAESQTTGKQS 56
           M  + S  + A  +  +   +G ++   +A G +    S+T S+    +TA S+TT   +
Sbjct: 111 MAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVST 170

Query: 57  LIPRTPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIA- 115
           +   T  A    S TT +   G+E +T           S +    T +         ++ 
Sbjct: 171 VGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST 230

Query: 116 ----CSPVSSVRKKPKVTPTKESYTEEIV---SEAESHVSGISRIVLPTE--KTTGARRS 166
                +  S+   +     T  S T ++    SE     +G       TE  +T  A   
Sbjct: 231 TGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTE 290

Query: 167 KAKSLTDPSQESHTEAISDAETSSSDISFSGIATRRTRSM-QRKLKAQTEKKDSKIVPGN 225
            +K+ T  +    T A S   +  +  S  G  T    ++     K  T   +   V   
Sbjct: 291 DSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAA 350

Query: 226 EKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQAN 285
             + +       ++ T  T+  +  + S +      ++    + +  S+E   T    A+
Sbjct: 351 GSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETT--TAS 408

Query: 286 VESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNK 345
            E  + T  +    +     ITD     +E ++     SE+  T++   V +  +     
Sbjct: 409 TEGSEATTVSTTGSETTTVSITD-----SETTTTCTEGSEM--TAVSTTVFETTTASTEG 461

Query: 346 NAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTV 405
           + +++ S  +SE    S   +  T      +  K +    S+ T   + G     E +TV
Sbjct: 462 SEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTG----LETTTV 517

Query: 406 ISVSEDMNSEGNVDFECDTKLYTSAPNT---SQGKDNSVLLVLSSDESQQS--------- 453
            ++  D  +      E      T +  T   ++G +N+ +    S+ +  S         
Sbjct: 518 FTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTT 577

Query: 454 --ENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKA 511
             E SE    +    E +      SG T + +  +    + T    +   +    E   A
Sbjct: 578 STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 637

Query: 512 SEVAIEEEKEEEEDEKSEEDSSDHDENED-EFSDEEDFLNSTKAKLLKLTSS 562
           S    E         ++   S++  E      +D E  + ST      +TS+
Sbjct: 638 STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITST 689


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 94/502 (18%), Positives = 176/502 (35%), Gaps = 41/502 (8%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T     G      E+T  S S    SE N
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-----SETTTASTS---GSETN 1214

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
                C T   TS P+++  + N+  ++ S      + + E    +L   E +    + SG
Sbjct: 1215 T--ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASG 1272

Query: 478  DT-GSLSCDNALFVIDTTPGMS 498
             T  S +  +  FV+     +S
Sbjct: 1273 ATAASTTVSSTTFVLTKATDVS 1294



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 94/502 (18%), Positives = 176/502 (35%), Gaps = 41/502 (8%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T     G      E+T  S S    SE N
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-----SETTTASTS---GSETN 1214

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
                C T   TS P+++  + N+  ++ S      + + E    +L   E +    + SG
Sbjct: 1215 T--ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASG 1272

Query: 478  DT-GSLSCDNALFVIDTTPGMS 498
             T  S +  +  FV+     +S
Sbjct: 1273 ATAASTTVSSTTFVLTKATDVS 1294



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 92/503 (18%), Positives = 179/503 (35%), Gaps = 33/503 (6%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T      GS+    ST  S +   ++ G+
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTT-ASTAGSETTTASTAGSETTTASTSGS 1221

Query: 418  -VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLS 476
              +  C T   TS P+++  + N+  ++ S      + + E    +L   E +    + S
Sbjct: 1222 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1281

Query: 477  GDT-GSLSCDNALFVIDTTPGMS 498
            G T  S +  +  FV+     +S
Sbjct: 1282 GATAASTTVSSTTFVLTKATDVS 1304



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 42/193 (21%), Positives = 72/193 (37%), Gaps = 8/193 (4%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDART--TAESQTTGKQSLIPRTPKARKRKSRTTG 73
            +SA  S   + +  G +    S+ GS+  T  TA S+TT   +    T  A    S T  
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1225

Query: 74   SLPKGTEPSTDGETSEAESNYSVSEHHDTI-----LRVTRRRQILIACSPVSSVRKKPKV 128
            +   G+E ST        +   +     TI     L  T         + VS        
Sbjct: 1226 ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATA 1285

Query: 129  TPTKESYTEEIVSEA-ESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAE 187
              T  S T  ++++A +  +  I+   +   +TTG R + + S+T       T + +   
Sbjct: 1286 ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHT 1345

Query: 188  TSSSDISFSGIAT 200
                 ++ SG+ T
Sbjct: 1346 VPGIVLNTSGLGT 1358


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 92/503 (18%), Positives = 179/503 (35%), Gaps = 33/503 (6%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T      GS+    ST  S +   ++ G+
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTT-ASTAGSETTTASTAGSETTTASTSGS 1221

Query: 418  -VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLS 476
              +  C T   TS P+++  + N+  ++ S      + + E    +L   E +    + S
Sbjct: 1222 ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1281

Query: 477  GDT-GSLSCDNALFVIDTTPGMS 498
            G T  S +  +  FV+     +S
Sbjct: 1282 GATAASTTVSSTTFVLTKATDVS 1304



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 42/193 (21%), Positives = 72/193 (37%), Gaps = 8/193 (4%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDART--TAESQTTGKQSLIPRTPKARKRKSRTTG 73
            +SA  S   + +  G +    S+ GS+  T  TA S+TT   +    T  A    S T  
Sbjct: 1166 SSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNT 1225

Query: 74   SLPKGTEPSTDGETSEAESNYSVSEHHDTI-----LRVTRRRQILIACSPVSSVRKKPKV 128
            +   G+E ST        +   +     TI     L  T         + VS        
Sbjct: 1226 ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATA 1285

Query: 129  TPTKESYTEEIVSEA-ESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAE 187
              T  S T  ++++A +  +  I+   +   +TTG R + + S+T       T + +   
Sbjct: 1286 ASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHT 1345

Query: 188  TSSSDISFSGIAT 200
                 ++ SG+ T
Sbjct: 1346 VPGIVLNTSGLGT 1358


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 91/487 (18%), Positives = 178/487 (36%), Gaps = 46/487 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEI-VSEAESHV----SGISRIVLPTEKTTGARRSKAKSLTDPSQESH--TEAISDAE 187
             T  +  + +E+ V    SG + + +   +TT    + +++ T  ++ S   T +I+ +E
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSE 731

Query: 188  TSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHL 247
            T+++    S   T  T   +    + T  + +     + +  + + + SE +       +
Sbjct: 732  TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETT-------M 784

Query: 248  QARSLSEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETKQ 294
             +   SE  K +  ++     F+  S   I   T  E   V +             ET  
Sbjct: 785  ASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTT 844

Query: 295  NCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAVS 349
                   +    + EG E    S++    +       + T+     S+  +T    +  +
Sbjct: 845  TTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETT 904

Query: 350  VHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEES 403
              S   SE    S T +  T      +    +  + S+LT     G       ++  E +
Sbjct: 905  TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964

Query: 404  TVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEEDT 462
            TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E T
Sbjct: 965  TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024

Query: 463  LCFVENS 469
            +   E S
Sbjct: 1025 ITSTEGS 1031



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 94/502 (18%), Positives = 176/502 (35%), Gaps = 41/502 (8%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T     G      E+T  S S    SE N
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-----SETTTASTS---GSETN 1214

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
                C T   TS P+++  + N+  ++ S      + + E    +L   E +    + SG
Sbjct: 1215 T--ACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASG 1272

Query: 478  DT-GSLSCDNALFVIDTTPGMS 498
             T  S +  +  FV+     +S
Sbjct: 1273 ATAASTTVSSTTFVLTKATDVS 1294



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 83/392 (21%), Positives = 158/392 (40%), Gaps = 27/392 (6%)

Query: 160 TTGARRSKAKSLTDPSQESHTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDS 219
           T   RR   K+  DP++  HT + S + +SSS  S S  ++  + S      + +    S
Sbjct: 128 TEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 187

Query: 220 KIVPGNEK--QIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENI 277
                  K  +++         D+R+         S   +P+  +N    + S +  EN 
Sbjct: 188 SSSTSFSKPHKLMKEHKEKPSKDSREHK-------SAFKEPSRDHNKSSKESSKKPKENK 240

Query: 278 LTVHEQANVE-SLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVS 336
               E+   + + KE K   K+   D+N +T    +  +  S+   +S+ ++ S ++   
Sbjct: 241 PLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKR-K 299

Query: 337 QRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWN-NNKKSPIKASDLTKFGD-C 394
           +  S    K+  S    + + +  K   +  + V++G+    ++ S  K S L  F D  
Sbjct: 300 KSSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIV 359

Query: 395 GGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSD----ES 450
             +D + E  + S S+             +  +T +    QG   S++  L SD    ES
Sbjct: 360 DPNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEES 419

Query: 451 QQSENSENEEDTLCFVENSGQRE---SLS--GDTGSLSCDNALFVIDTTPGMSADKNFYL 505
            + E+++N+ +    V   G R    SLS   D+ S S  + L      P +  + N  L
Sbjct: 420 DEVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQIL 479

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDE 537
           E +       I++ K +++ +  E D +  DE
Sbjct: 480 EVKS-----PIKQSKSDKQIKNGECDKAYLDE 506


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 91/422 (21%), Positives = 150/422 (35%), Gaps = 64/422 (15%)

Query: 131 TKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSS 190
           T +   EE   E E  + G    +   E   G RRS + S ++ +  S     S+  ++S
Sbjct: 350 TTDYQVEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTS 409

Query: 191 SDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNS-EDSDTRQTSHLQA 249
                  +  + T +     +   EKK  K   G E +   +  N+ E S  ++      
Sbjct: 410 K------MNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCP 463

Query: 250 RSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDE 309
              SE   P      F+   S + SE    V         KE+K+     D + NG+  E
Sbjct: 464 EKESEEGCPK---RGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKE 520

Query: 310 GKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFAT 369
            ++   K S+     E+  T       +       K +    S   SE            
Sbjct: 521 SEDDLNKESE----EEVGPTK------ESEEDDSEKESDEDCSEKQSE------------ 558

Query: 370 VEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTS 429
                  +  +   + + L K  D  GS+ E    V+    + N   N +FE D      
Sbjct: 559 -------DGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVL 611

Query: 430 APNTSQGKDNSVLLVLSSDESQQSENSENEEDTL--CFVENSGQRES--LSGDTGSLSCD 485
               S+            +  + S+  E EEDT    F + S ++E    + + G  + D
Sbjct: 612 DEEGSE-----------REFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660

Query: 486 NALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDE 545
                 D      AD+  + E +DK  E A  +E E+ +++  E+D    D NE  F +E
Sbjct: 661 KKAEEGD------ADEKLFEESDDKEDEDADGKEVEDADEKLFEDD----DSNEKLFDEE 710

Query: 546 ED 547
           ED
Sbjct: 711 ED 712



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 7/152 (4%)

Query: 398 DDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSE 457
           + EEE      SE+ +SE   D +C  K   S   + +  + + L     +E  + E  E
Sbjct: 528 ESEEEVGPTKESEEDDSEKESDEDCSEK--QSEDGSEREFEENGLEKDLDEEGSEKELHE 585

Query: 458 NEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIE 517
           N  D    +E +    S   D GS   +  L    +      D +   EEED   +V  +
Sbjct: 586 NVLDKE--LEENDSENSEFEDDGS---EKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDD 640

Query: 518 EEKEEEEDEKSEEDSSDHDENEDEFSDEEDFL 549
           E  E+E++E ++E   +  + + E  D ++ L
Sbjct: 641 ESDEKEDEEYADEKGLEAADKKAEEGDADEKL 672


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 91/422 (21%), Positives = 150/422 (35%), Gaps = 64/422 (15%)

Query: 131 TKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSS 190
           T +   EE   E E  + G    +   E   G RRS + S ++ +  S     S+  ++S
Sbjct: 350 TTDYQVEETSREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTS 409

Query: 191 SDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNS-EDSDTRQTSHLQA 249
                  +  + T +     +   EKK  K   G E +   +  N+ E S  ++      
Sbjct: 410 K------MNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCP 463

Query: 250 RSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDE 309
              SE   P      F+   S + SE    V         KE+K+     D + NG+  E
Sbjct: 464 EKESEEGCPK---RGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKE 520

Query: 310 GKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFAT 369
            ++   K S+     E+  T       +       K +    S   SE            
Sbjct: 521 SEDDLNKESE----EEVGPTK------ESEEDDSEKESDEDCSEKQSE------------ 558

Query: 370 VEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTS 429
                  +  +   + + L K  D  GS+ E    V+    + N   N +FE D      
Sbjct: 559 -------DGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVL 611

Query: 430 APNTSQGKDNSVLLVLSSDESQQSENSENEEDTL--CFVENSGQRES--LSGDTGSLSCD 485
               S+            +  + S+  E EEDT    F + S ++E    + + G  + D
Sbjct: 612 DEEGSE-----------REFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660

Query: 486 NALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDE 545
                 D      AD+  + E +DK  E A  +E E+ +++  E+D    D NE  F +E
Sbjct: 661 KKAEEGD------ADEKLFEESDDKEDEDADGKEVEDADEKLFEDD----DSNEKLFDEE 710

Query: 546 ED 547
           ED
Sbjct: 711 ED 712



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 37/152 (24%), Positives = 64/152 (42%), Gaps = 7/152 (4%)

Query: 398 DDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSE 457
           + EEE      SE+ +SE   D +C  K   S   + +  + + L     +E  + E  E
Sbjct: 528 ESEEEVGPTKESEEDDSEKESDEDCSEK--QSEDGSEREFEENGLEKDLDEEGSEKELHE 585

Query: 458 NEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIE 517
           N  D    +E +    S   D GS   +  L    +      D +   EEED   +V  +
Sbjct: 586 NVLDKE--LEENDSENSEFEDDGS---EKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDD 640

Query: 518 EEKEEEEDEKSEEDSSDHDENEDEFSDEEDFL 549
           E  E+E++E ++E   +  + + E  D ++ L
Sbjct: 641 ESDEKEDEEYADEKGLEAADKKAEEGDADEKL 672


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 58/277 (20%), Positives = 106/277 (38%), Gaps = 46/277 (16%)

Query: 286 VESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNK 345
           VE   E ++  +D ++D++G   E   I +K  +    +  +   +        +TP  K
Sbjct: 24  VEEDSEDEEMSEDEEDDSSG---EEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKK 80

Query: 346 NAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNN----------KKS---PIKASDLTKFG 392
            AV+      +    K++T   A    G+              KK    P K +   K  
Sbjct: 81  AAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNA 140

Query: 393 DCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQ 452
               SD+EE+       ED   E   + E +     +A      +D         D+   
Sbjct: 141 KKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDED-----DEDDEDD 195

Query: 453 SENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTP--GMSADKNFYLEEEDK 510
            ++ ++EED                       D+    ++TTP  G  A K   ++ ++ 
Sbjct: 196 EDDDDDEED-----------------------DSEEEAMETTPAKGKKAAKVVPVKAKNV 232

Query: 511 ASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           A +   EE+ E+E+D+  E+D  D DE+++E  +EE+
Sbjct: 233 AEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEE 269



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 12/46 (26%), Positives = 27/46 (58%)

Query: 520 KEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTSSSID 565
           K+E+ DE+ ++DS + +E++++  ++ED +     K      +S D
Sbjct: 141 KKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASED 186



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 15/57 (26%), Positives = 31/57 (54%), Gaps = 2/57 (3%)

Query: 510 KASEVAIEEEKEEEEDEKSEEDSSD--HDENEDEFSDEEDFLNSTKAKLLKLTSSSI 564
           KA+  A   E E++ED++ +ED  D   D++E+E  +         AK++ + + ++
Sbjct: 176 KAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNV 232


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 133/685 (19%), Positives = 247/685 (36%), Gaps = 119/685 (17%)

Query: 5    RSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKA 64
            + +R   S   +S E + Q    +      PE+S  SD +T  E   +G+     +    
Sbjct: 394  KPSRVLYSSTESSDEEALQNKKISTSCSVIPETSN-SDMQTKKEYVVSGEHK--QKGKVK 450

Query: 65   RKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVS---- 120
            RK K++      +  +   +G+ +   +N +V+   D   +         + SP      
Sbjct: 451  RKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSL 510

Query: 121  -----SVRKKPK---------VTPTKESYTEEIVSEAESHVSGISRIV---------LPT 157
                 S  K PK          TP K+ +T+  +S   S +S    +V         LP 
Sbjct: 511  HLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPE 570

Query: 158  EKTTGARRSKAKSLTDPS-----QESHTEAISDAETS----SSDISFSGIATRRTRSMQR 208
              +  + + K KS           E     I D + S    +SD +   +        + 
Sbjct: 571  SSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKH 630

Query: 209  KLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDD 268
            KLK +  +K+      ++K+I G     +  D+ +          E  K NF+ +D  +D
Sbjct: 631  KLKHKEREKEK-----HKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETED 685

Query: 269  FSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSE--L 326
                    +   HE   +E   + ++N KD          + +   E+  ++K  SE   
Sbjct: 686  LF------LNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSF 739

Query: 327  QDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEV-----------GRW 375
            ++  ++ L  +R + P +K+  S  ++L   A+ +S+       E+            + 
Sbjct: 740  REEKIKDLKEERENIPTDKD--SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKE 797

Query: 376  NNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDF-ECDTKLYTSAPNTS 434
               K+S IK  D+ K         E+E  +    E  + +  +D  EC  K+        
Sbjct: 798  KPEKRSQIKEKDIEKM---ERKTFEKEKKI--KHEHKSEKDKLDLSECVDKI-------- 844

Query: 435  QGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTT 494
            + KD      L S  +++      +      ++ +  RE                     
Sbjct: 845  KEKDK-----LYSHHTEKCHKEGEKSKNTAAIKKTDDREK-------------------- 879

Query: 495  PGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKA 554
                 D+    E+ +K   +A  +EK   E +  + D+S++ ++E   + E+D     K 
Sbjct: 880  SREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKE 939

Query: 555  KLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNELLQKAVITPDFE 614
            K     S +I     I++     I  + +K Q  K     +KEK K+E L+    TPD +
Sbjct: 940  KSRDKESINITNSKHIQEEKKSSI-VDGNKAQHEKP--LSLKEKTKDEPLK----TPDGK 992

Query: 615  KNHCVPPYSESKYQLQKKRRKERQK 639
            +        + K      R KER K
Sbjct: 993  E--------KDKKDKDIDRYKERDK 1009



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 28/189 (14%)

Query: 180  TEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDS 239
            ++++SDAE+ S  +S S +A +    +Q+K               N  QI+ + +++++ 
Sbjct: 1473 SQSLSDAESISKHMSLSYVANQEPGILQQK---------------NAVQIISSALDTDNE 1517

Query: 240  DTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKE-------T 292
             T+ T +     L ++ K + +   + D     +S N    +    + S K+       T
Sbjct: 1518 STKDTENTFV--LGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDAST 1575

Query: 293  KQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLV----SQRHSTPQNKNAV 348
            + N           +  G E+   ++  + +S  ++  L+ LV    S+  S     NA 
Sbjct: 1576 QLNTHYAFSKLTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHLSRCDSDLCEMNAG 1635

Query: 349  SVHSNLNSE 357
                NLN +
Sbjct: 1636 MPKGNLNEQ 1644


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 133/685 (19%), Positives = 247/685 (36%), Gaps = 119/685 (17%)

Query: 5    RSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKA 64
            + +R   S   +S E + Q    +      PE+S  SD +T  E   +G+     +    
Sbjct: 417  KPSRVLYSSTESSDEEALQNKKISTSCSVIPETSN-SDMQTKKEYVVSGEHK--QKGKVK 473

Query: 65   RKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVS---- 120
            RK K++      +  +   +G+ +   +N +V+   D   +         + SP      
Sbjct: 474  RKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSL 533

Query: 121  -----SVRKKPK---------VTPTKESYTEEIVSEAESHVSGISRIV---------LPT 157
                 S  K PK          TP K+ +T+  +S   S +S    +V         LP 
Sbjct: 534  HLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPE 593

Query: 158  EKTTGARRSKAKSLTDPS-----QESHTEAISDAETS----SSDISFSGIATRRTRSMQR 208
              +  + + K KS           E     I D + S    +SD +   +        + 
Sbjct: 594  SSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKH 653

Query: 209  KLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDD 268
            KLK +  +K+      ++K+I G     +  D+ +          E  K NF+ +D  +D
Sbjct: 654  KLKHKEREKEK-----HKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETED 708

Query: 269  FSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSE--L 326
                    +   HE   +E   + ++N KD          + +   E+  ++K  SE   
Sbjct: 709  LF------LNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSF 762

Query: 327  QDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEV-----------GRW 375
            ++  ++ L  +R + P +K+  S  ++L   A+ +S+       E+            + 
Sbjct: 763  REEKIKDLKEERENIPTDKD--SEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKE 820

Query: 376  NNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDF-ECDTKLYTSAPNTS 434
               K+S IK  D+ K         E+E  +    E  + +  +D  EC  K+        
Sbjct: 821  KPEKRSQIKEKDIEKM---ERKTFEKEKKI--KHEHKSEKDKLDLSECVDKI-------- 867

Query: 435  QGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTT 494
            + KD      L S  +++      +      ++ +  RE                     
Sbjct: 868  KEKDK-----LYSHHTEKCHKEGEKSKNTAAIKKTDDREK-------------------- 902

Query: 495  PGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKA 554
                 D+    E+ +K   +A  +EK   E +  + D+S++ ++E   + E+D     K 
Sbjct: 903  SREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKE 962

Query: 555  KLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNELLQKAVITPDFE 614
            K     S +I     I++     I  + +K Q  K     +KEK K+E L+    TPD +
Sbjct: 963  KSRDKESINITNSKHIQEEKKSSI-VDGNKAQHEKP--LSLKEKTKDEPLK----TPDGK 1015

Query: 615  KNHCVPPYSESKYQLQKKRRKERQK 639
            +        + K      R KER K
Sbjct: 1016 E--------KDKKDKDIDRYKERDK 1032



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 37/189 (19%), Positives = 77/189 (40%), Gaps = 28/189 (14%)

Query: 180  TEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDS 239
            ++++SDAE+ S  +S S +A +    +Q+K               N  QI+ + +++++ 
Sbjct: 1496 SQSLSDAESISKHMSLSYVANQEPGILQQK---------------NAVQIISSALDTDNE 1540

Query: 240  DTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKE-------T 292
             T+ T +     L ++ K + +   + D     +S N    +    + S K+       T
Sbjct: 1541 STKDTENTFV--LGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDAST 1598

Query: 293  KQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLV----SQRHSTPQNKNAV 348
            + N           +  G E+   ++  + +S  ++  L+ LV    S+  S     NA 
Sbjct: 1599 QLNTHYAFSKLTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHLSRCDSDLCEMNAG 1658

Query: 349  SVHSNLNSE 357
                NLN +
Sbjct: 1659 MPKGNLNEQ 1667


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 48/210 (22%), Positives = 91/210 (43%), Gaps = 19/210 (9%)

Query: 497  MSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKL 556
            ++ ++   LE   ++SE   EEE EEEE+E+ EE+  + +E E+E  +EE+ + S+  +L
Sbjct: 1054 VTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRL 1113

Query: 557  LKLTSSSID---PGLSIKQLGGLYINFNADKLQSNKRTLTQI---------KEKKKNELL 604
             K  S +I    P +  K+ G      N+          T++         +E+   +L 
Sbjct: 1114 TKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLE 1173

Query: 605  QKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKNDLKAL 664
                I  + E++   P   ++      K+R+  ++   D      A    N + +D   L
Sbjct: 1174 PTCEI--EVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNL 1231

Query: 665  KMRASMDP-----KRFYKKNDRDGFPKYFQ 689
            K  +  +P     K+ + K  + G  K+ Q
Sbjct: 1232 KEGSKDNPEPLKCKQVWPKGTKRGLSKWRQ 1261



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 50/207 (24%), Positives = 78/207 (37%), Gaps = 18/207 (8%)

Query: 430  APNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALF 489
            +PNTS G+     L+   +E ++ E  E EE+     E  G+ E   G+      D A  
Sbjct: 1334 SPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEE-----EEEGEEEEGGGNVEK-DPDGAKS 1387

Query: 490  VIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFL 549
                 P +S +K      ED A     EEE+EE+E+    ED    DE++      E   
Sbjct: 1388 QEKEEPEISTEK------EDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEK 1441

Query: 550  NSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNELLQKAVI 609
                 +  K    + +  L +    G   + N + L      LT     +  EL      
Sbjct: 1442 EELPRESFKEVLENQETFLDLNVQPG---HSNPEVLMDCGVDLTASCNSEPKELAGDPEA 1498

Query: 610  TPDFEKNHCVPPYSESKYQLQKKRRKE 636
             P+ ++    PP  E   +  +K  KE
Sbjct: 1499 VPESDEE---PPPGEQAQKQDQKNSKE 1522



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 24/104 (23%), Positives = 42/104 (40%), Gaps = 5/104 (4%)

Query: 444  VLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNF 503
            +L S+ +   E  E E++    +E +   E    +  S   ++       +P     KN 
Sbjct: 990  ILISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSR-----QSPAKVQSKNK 1044

Query: 504  YLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
            YL   +         +  E   E SEE+  + DE E+E  +EE+
Sbjct: 1045 YLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEE 1088


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 94/488 (19%), Positives = 170/488 (34%), Gaps = 48/488 (9%)

Query: 17   SAESSGQKSFAANGIQAHPESSTGSD--ARTTAESQTTGKQSLIPRTPKARKRKSRTTGS 74
            S E S   + +  G +   +S+ GS   A +TA S+TT   +       A    S TT +
Sbjct: 557  STEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSA 616

Query: 75   LPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKES 134
               G+E +T   TS   +  S      T +  T     +     VS+   +  +T T+ S
Sbjct: 617  STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTM-----VSTTGSERTITSTEGS 671

Query: 135  YTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
             T  + +               T   TG+  +K  +    +  + TE    +E +++ I+
Sbjct: 672  ETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG---SEITTASIT 728

Query: 195  FSGIATRRTRSMQRKLKAQTEKKD--SKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSL 252
             S   T  T   +    A TE  +  S    G+E     T  ++  S+T   S + + + 
Sbjct: 729  GSETTTASTEGSE-TTTASTEGSETTSASTTGSET----TTASTTSSETTMASIMGSETT 783

Query: 253  ------SEINKPNFYNNDFDDDFSHRSSENI--LTVHEQANVESL-----------KETK 293
                  SE  K +  ++     F+  S   I   T  E   V +             ET 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETT 843

Query: 294  QNCKDLDEDANGITDEGKEINEKSSQLKNLSEL-----QDTSLQQLVSQRHSTPQNKNAV 348
                    +    + EG E    S++    +       + T+     S+  +T    +  
Sbjct: 844  TTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSET 903

Query: 349  SVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCG------GSDDEEE 402
            +  S   SE    S T +  T      +    +  + S+LT     G       ++  E 
Sbjct: 904  TTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSET 963

Query: 403  STVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSE-NSENEED 461
            +TV ++  +  +      E  T     +  T+   + S    +SS  S+ +  ++   E 
Sbjct: 964  TTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTET 1023

Query: 462  TLCFVENS 469
            T+   E S
Sbjct: 1024 TITSTEGS 1031



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 94/502 (18%), Positives = 176/502 (35%), Gaps = 41/502 (8%)

Query: 16   ASAESSGQKSFAANGIQAHPESSTGSDARTTAE-------------SQTTGKQSLIPRTP 62
            AS  +S   + +  G +  P S+ GS+  TT               S+TT   +    T 
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETT 874

Query: 63   KARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSV 122
             A    S TT +  +G+E +T   T  +E+  + +E  +     T   +   A +  S  
Sbjct: 875  TATTIGSETTTASTEGSETTTT-STEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 123  ----RKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQES 178
                 +  ++T    + +E I   AE   +     +     T     S+  +++    E+
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 179  HTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSED 238
             T +I  +ET++   + S   T  T   +  +   TE  ++  V     +         +
Sbjct: 994  TTASIEGSETTTVSSTGSETTTVSTTGTETTI-TSTEGSETTTVTTAGSETTAVYTTGSE 1052

Query: 239  SDTRQTSHLQARSLSEINKPNFYNNDFD-DDFSHRSSENILTVHEQANVESLKETKQNCK 297
            + T  T   +  ++S         +  D +  +  +S +  T    A  E+        K
Sbjct: 1053 TTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSK 1112

Query: 298  DLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSE 357
                   G   E   ++  SS        + T+     S+  +     +  +  S + SE
Sbjct: 1113 TTTASTEG--SEATTVSTTSS--------ETTTASTTGSEMTTVFTTVSETTTVSTIGSE 1162

Query: 358  AVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGN 417
            A   S   + AT      +    +    S+ T     G      E+T  S S    SE N
Sbjct: 1163 ATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAG-----SETTTASTS---GSETN 1214

Query: 418  VDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSG 477
                C T   TS P+++  + N+  ++ S      + + E    +L   E +    + SG
Sbjct: 1215 T--ACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASG 1272

Query: 478  DT-GSLSCDNALFVIDTTPGMS 498
             T  S +  +  FV+     +S
Sbjct: 1273 ATAASTTVSSTTFVLTKATDVS 1294



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 99/564 (17%), Positives = 192/564 (34%), Gaps = 41/564 (7%)

Query: 27  AANGIQAHPESSTGSDAR--TTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTD 84
           +A G +    S+T S+    +TA S+TT   ++   T  A    S TT +   G+E +T 
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177

Query: 85  GETSEAESNYSVSEHHDTILRVTRRRQILIA-----CSPVSSVRKKPKVTPTKESYTEEI 139
                     S +    T +         ++      +  S+   +     T  S T ++
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237

Query: 140 V---SEAESHVSGISRIVLPTE--KTTGARRSKAKSLTDPSQESHTEAISDAETSSSDIS 194
               SE     +G       TE  +T  A    +K+ T  +    T A S   +  +  S
Sbjct: 238 STAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAS 297

Query: 195 FSGIATRRTRSM-QRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLS 253
             G  T    ++     K  T   +   V     + +       ++ T  T+  +  + S
Sbjct: 298 TMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTAS 357

Query: 254 EINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEI 313
            +      ++    + +  S+E   T    A+ E  + T  +    +     ITD     
Sbjct: 358 IMGSETSTDSTTGSETTTASTEGSETT--TASTEGSEATTVSTTGSETTTVSITD----- 410

Query: 314 NEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVG 373
           +E ++     SE+  T++   V +  +     + +++ S  +SE    S   +  T    
Sbjct: 411 SETTTTCTEGSEM--TAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468

Query: 374 RWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNT 433
             +  K +    S+ T   + G     E +TV ++  D  +      E      T +  T
Sbjct: 469 AGSETKTAYTTGSETTTASNTG----LETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 524

Query: 434 ---SQGKDNSVLLVLSSDESQQS-----------ENSENEEDTLCFVENSGQRESLSGDT 479
              ++G +N+ +    S+ +  S           E SE    +    E +      SG T
Sbjct: 525 TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 584

Query: 480 GSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENE 539
            + +  +    + T    +   +    E   AS    E         ++   S++  E  
Sbjct: 585 AASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETT 644

Query: 540 D-EFSDEEDFLNSTKAKLLKLTSS 562
               +D E  + ST      +TS+
Sbjct: 645 TVSTTDSETTMVSTTGSERTITST 668


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 36/157 (22%), Positives = 73/157 (46%), Gaps = 15/157 (9%)

Query: 392  GDCGGSDDEEESTVISVSEDMNSEGNVDFECDTK-LYTSAPNTSQGKDNSVLLVLSSDES 450
            GD    + E +S VI+   ++ S   +  E + + L         G  NS ++V  S E 
Sbjct: 2316 GDIMDGEAETDSVVIAGQPEVLSSQEMQVENELEDLIDELLERDGGSGNSTIIVSRSGED 2375

Query: 451  QQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDK 510
            +  E+   +E       N  Q  +L  +      ++++ ++D       D+  + +EED 
Sbjct: 2376 ESQEDVLMDEAP----SNLSQASTLQANR-----EDSMNILDPE-----DEEEHTQEEDS 2421

Query: 511  ASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
            +     E++ ++EE+E+ E++  D +++E E  DE+D
Sbjct: 2422 SGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDD 2458


>gi|167466187 integrin-binding sialoprotein precursor [Homo sapiens]
          Length = 317

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 30/109 (27%), Positives = 54/109 (49%), Gaps = 5/109 (4%)

Query: 446 SSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYL 505
           SS+E ++ E + NE +     E S + E    +  +LS     +  D TPG        +
Sbjct: 74  SSEEEEEEEETSNEGENN---EESNEDEDSEAENTTLSATTLGYGEDATPGTGYTGLAAI 130

Query: 506 EEEDKASEVAIEEEKEEEED--EKSEEDSSDHDENEDEFSDEEDFLNST 552
           +   KA ++  +  KE+E D  E+ EE+ ++++E+E E  + E  +N T
Sbjct: 131 QLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGT 179



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 29/104 (27%), Positives = 50/104 (48%), Gaps = 10/104 (9%)

Query: 501 KNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED--FLNSTKAKLLK 558
           K F ++    +SE   ++  EEEE+E   E++S+  EN +E +++ED    N+T +    
Sbjct: 56  KRFPVQGSSDSSEENGDDSSEEEEEE---EETSNEGENNEESNEDEDSEAENTTLSATTL 112

Query: 559 LTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNE 602
                  PG     L  + +   A  + +NK T    KEK+ +E
Sbjct: 113 GYGEDATPGTGYTGLAAIQLPKKAGDI-TNKAT----KEKESDE 151


>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
           sapiens]
          Length = 1907

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 74/387 (19%), Positives = 145/387 (37%), Gaps = 51/387 (13%)

Query: 195 FSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDT---RQTSHLQARS 251
           ++  AT   +++++ L  Q  +K+ ++    E +      NSE+SD+     T  LQ + 
Sbjct: 147 YNSAATDSEKAVEKTL--QDMEKNPELSKEREPEPEPVEANSEESDSVFSENTEDLQEQF 204

Query: 252 LSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGK 311
            ++ +             SH +S+      EQA+ ES +E  Q+   + E  N  T    
Sbjct: 205 TTQKHH------------SHANSQANHAQGEQASFESFEEMLQDKLKVPESENNKTSNSS 252

Query: 312 EINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTF---- 367
           +++ +  ++     L+      L ++  ST     A ++ S+  +  ++ SL   F    
Sbjct: 253 QVSNEQDKIDAYKLLKKEMTLDLKTKFGST-----ADALVSDDETTRLVTSLEDDFDEEL 307

Query: 368 --ATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTK 425
                 VG+ +   +       L  F D        +S V     D     N     + K
Sbjct: 308 DTEYYAVGKEDEENQEDFDELPLLTFTDGEDMKTPAKSGVEKYPTDKEQNSNE----EDK 363

Query: 426 LYTSAPNTSQGKDNSVLL------------------VLSSDESQQSENSENEEDTLCFVE 467
           +  + P   +  D ++L                    +  + S   E  E+++D L    
Sbjct: 364 VQLTVPPGIKNDDKNILTTWGDTIFSIVTGGEETRDTMDLESSSSEEEKEDDDDALVPDS 423

Query: 468 NSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEK 527
             G+ +S +  +   + D+ LF++D  P  + DK    E   K     ++E K     +K
Sbjct: 424 KQGKPQSATDYSDPDNVDDGLFIVD-IPKTNNDKEVNAEHHIKGKGRGVQESKRGLVQDK 482

Query: 528 SEEDSSDHDENEDEFSDEEDFLNSTKA 554
           +E +  + +      S   + LNS  A
Sbjct: 483 TELEDENQEGMTVHSSVHSNNLNSMPA 509



 Score = 30.8 bits (68), Expect = 4.9
 Identities = 88/399 (22%), Positives = 142/399 (35%), Gaps = 36/399 (9%)

Query: 275  ENILTVHEQANVES-LKETKQNCKDLDEDANGITDEGKEINEKSSQL-KNLSELQDTSLQ 332
            EN   V + +N E  +KE+K++ ++  +    ++DE  +  +K   L KN   L DT+  
Sbjct: 1226 ENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEKNQEILDDTAKN 1285

Query: 333  QLVSQRHSTPQN-KNAVSVHSNLNSEAVMKSL----TQTFATVEVGRWNNNKKSPIKASD 387
              V       QN KN   +  N  S   +K +       F+ V++   N  K S  K   
Sbjct: 1286 LRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIA-LNEAKLSEEKVK- 1343

Query: 388  LTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQG-----KDNSVL 442
                 +C     EE + +    E +  E     E  +KL+       +      KD  V 
Sbjct: 1344 ----SEC-HRVQEENARLKKKKEQLQQE----IEDWSKLHAELSEQIKSFEKSQKDLEVA 1394

Query: 443  LVLSSDESQQSENSENEEDTL-CFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADK 501
            L    D      N   + + L C  E+ GQ +   G   S    N     D    M    
Sbjct: 1395 LTHKDDNINALTNCITQLNLLECESESEGQNK---GGNDSDELANGEVGGDRNEKMKNQI 1451

Query: 502  NFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTS 561
               ++     + +++ EE  +    K     S     ED+    ED  NS +A    L  
Sbjct: 1452 KQMMDVSRTQTAISVVEEDLKLLQLKLRASVSTKCNLEDQVKKLEDDRNSLQAAKAGLED 1511

Query: 562  SSIDPGLSIKQLGGLY--INFNADKLQSNKRTLTQIKEKKKNELLQKAVITPDFEKNHCV 619
                    ++ L  LY        K  S +    Q +E + +   +KAV   +  K +  
Sbjct: 1512 ECKTLRQKVEILNELYQQKEMALQKKLSQEEYERQEREHRLSAADEKAVSAAEEVKTY-K 1570

Query: 620  PPYSESKYQLQKKRRK------ERQKTAGDGWFGMKAPE 652
                E + +LQK  R         +K A + W   +A E
Sbjct: 1571 RRIEEMEDELQKTERSFKNQIATHEKKAHENWLKARAAE 1609


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 24/111 (21%)

Query: 437 KDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPG 496
           +D +V+ + SSDE ++ E  E EE+     E   + E    +                  
Sbjct: 876 EDLTVININSSDEEEEEEEEEEEEEE----EEEEEEEDFEEE------------------ 913

Query: 497 MSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
              D+  Y EEE++  E   EEE EEEE E  EE+  + +E E+E  + ED
Sbjct: 914 -EEDEEEYFEEEEEEEE-EFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 21/44 (47%), Positives = 30/44 (68%), Gaps = 1/44 (2%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDEN-EDEFSDEEDF 548
           EEE++  E   EEE+EEEE+E  EE+  D +E  E+E  +EE+F
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 3/77 (3%)

Query: 473 ESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEE---EKEEEEDEKSE 529
           E   G  G  + +  L VI+       ++    EEE++  E   EE   E+EE+E+E  E
Sbjct: 863 EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE 922

Query: 530 EDSSDHDENEDEFSDEE 546
           E+  + +E E+EF +EE
Sbjct: 923 EEEEEEEEFEEEFEEEE 939



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 17/43 (39%), Positives = 27/43 (62%)

Query: 505 LEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           LEE+     +   +E+EEEE+E+ EE+  + +E ED   +EED
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEED 916


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 78/390 (20%), Positives = 149/390 (38%), Gaps = 66/390 (16%)

Query: 198  IATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSE-DSDTRQTSHLQARSLSEIN 256
            +A +R +  ++K + + +KK  +     E++     + ++ + +TR+   L+A  L +  
Sbjct: 812  LAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA--LQKSQ 869

Query: 257  KPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEK 316
            K      + +    ++  E IL + ++  +E L+  K               E +E++  
Sbjct: 870  KEAELTRELEKQKENKQVEEILRLEKE--IEDLQRMK---------------EQQELSLT 912

Query: 317  SSQLKNLSELQDTSLQQLVSQRHSTPQN-----------------KNAVSVHSNLNSEAV 359
             + L+ L E +D  L++L  +     Q                  + ++SV S  +SE  
Sbjct: 913  EASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELA 972

Query: 360  MKS--------LTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSED 411
              +         +Q +   EV           K  D     + G SD  + ++ I  S+D
Sbjct: 973  ESACEEKPNFNFSQPYPEEEVDEGFEADDDAFK--DSPNPSEHGHSD--QRTSGIRTSDD 1028

Query: 412  MNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQ 471
             + E       D  +  +   TS   D++VLL  S  +S    NS + E T C  +N+G 
Sbjct: 1029 SSEE-------DPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAGD 1081

Query: 472  RESLSGD---------TGSLSCDNAL-FVIDTTPGMSADKNFYLEEEDKASEVAIEEEKE 521
              S  GD          G+++  +++ F        S D    +   + +       E  
Sbjct: 1082 LPSPDGDYDYDQDDYEDGAITSGSSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEGA 1141

Query: 522  EEEDEKSEEDSSDHDENEDEFSDEEDFLNS 551
            +   E SEED     + +DE S   D + S
Sbjct: 1142 QSSFEDSEEDFDSRFDTDDELSYRRDSVYS 1171


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 106/516 (20%), Positives = 197/516 (38%), Gaps = 84/516 (16%)

Query: 60  RTPKARKRKSRTTGSLPKGTEPSTDG-----ETSEAESNYSVSEHHDTILRVTRRRQILI 114
           + PK  K K++ +     G+E   D      E S   S+    +  D  L+ +R+ Q   
Sbjct: 145 KLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQ-SRKGQ--- 200

Query: 115 ACSPVSSVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDP 174
                    +K K  P  ES  E+   +A   +  +++     +K     R + K   + 
Sbjct: 201 ------KKNQKNKPGPNIESGNED--DDASFKIKTVAQ-----KKAEKKERERKKRDEEK 247

Query: 175 SQESHTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKK----DSKIVPGNEKQIV 230
           ++    +   + ET   D S       + +  QRK + +T K     D+ ++P +E++  
Sbjct: 248 AKLRKLKEKEELETGKKDQS-------KQKESQRKFEEETVKSKVTVDTGVIPASEEK-A 299

Query: 231 GTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLK 290
            TP  +ED +         +   +  K      + + +     S+  +   ++A +  LK
Sbjct: 300 ETPTAAEDDNEGD------KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA-LAKLK 352

Query: 291 ETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSV 350
           E ++  K  +E+        +E+  K  + + L + +    +Q   +R    + +  +  
Sbjct: 353 EEEERQKREEEER---IKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLT 409

Query: 351 HSN----LNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVI 406
            S       +EA +K L Q        + +  KK PI       + D       ++    
Sbjct: 410 KSQREARARAEATLK-LLQAQGVEVPSKDSLPKKRPI-------YEDKKRKKIPQQLESK 461

Query: 407 SVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFV 466
            VSE M            +L  +     QG       V   +E+      E EEDT    
Sbjct: 462 EVSESM------------ELCAAVEVMEQG-------VPEKEETPPPVEPEEEEDT---- 498

Query: 467 ENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDE 526
           E++G       D  +++ D     ++        K    EEE++  E   +EE EEEE+E
Sbjct: 499 EDAGL-----DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEE 553

Query: 527 KSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTSS 562
           + E + S+ DE +++ SDE+D   +   K  K  SS
Sbjct: 554 EGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS 589



 Score = 36.6 bits (83), Expect = 0.089
 Identities = 58/288 (20%), Positives = 107/288 (37%), Gaps = 28/288 (9%)

Query: 263 NDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKN 322
           +D D D      E      EQ   +S  + K+  K  D D + I    KE+ E S + + 
Sbjct: 15  DDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDIL---KELEELSLEAQG 71

Query: 323 LSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSP 382
           +   ++T   +        P   N     S    +   K   Q+F   +     + K S 
Sbjct: 72  IKADRETVAVK--------PTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED-KDSK 122

Query: 383 IKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVL 442
            K +   K     GSDD+++   +       ++         K       + + +DNS  
Sbjct: 123 SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQ---------KSNKKWDGSEEDEDNSKK 173

Query: 443 LVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTG-----SLSCDNALFVIDTTPGM 497
           +   S  +   E+ +  ++ L      GQ+++     G         D+A F I T    
Sbjct: 174 IKERSRINSSGESGDESDEFL--QSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231

Query: 498 SADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDE 545
            A+K     ++    +  + + KE+EE E  ++D S   E++ +F +E
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEE 279



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 76/395 (19%), Positives = 148/395 (37%), Gaps = 57/395 (14%)

Query: 264 DFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNL 323
           DFD+D   +  E +    E   +++ +ET    K  + +    T + K+   +  + ++ 
Sbjct: 52  DFDEDDILKELEELSL--EAQGIKADRETVA-VKPTENNEEEFTSKDKKKKGQKGKKQSF 108

Query: 324 SELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPI 383
            +     L+   S+   T + K  V ++S  + +     L               KK+  
Sbjct: 109 DDNDSEELEDKDSKSKKTAKPK--VEMYSGSDDDDDFNKLP--------------KKAKG 152

Query: 384 KASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTS-----------APN 432
           KA    K  D G  +DE+ S  I     +NS G    E D  L +             PN
Sbjct: 153 KAQKSNKKWD-GSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPN 211

Query: 433 TSQG-KDNSVLLVLSSDESQQSENSENE----EDTLCFVENSGQRESLSGDTGSLSCDNA 487
              G +D+     + +   +++E  E E    ++    +    ++E L  +TG       
Sbjct: 212 IESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEEL--ETGKK----- 264

Query: 488 LFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
               D +    + + F  EEE   S+V ++       +EK+E  ++  D+NE +   ++ 
Sbjct: 265 ----DQSKQKESQRKF--EEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDK 318

Query: 548 FLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNELLQKA 607
                + +  +          ++K +         ++ +  +    +IK  ++ E  +K 
Sbjct: 319 KKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378

Query: 608 VITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAG 642
               + EK        E K Q ++K RKER K  G
Sbjct: 379 EERLEQEKR-------ERKKQ-KEKERKERLKKEG 405


>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
           sapiens]
          Length = 707

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 26/200 (13%)

Query: 431 PNTSQGKDNSVLLVLSSDESQQSENSENEEDT----LCFVEN--SGQRESLSGDTGSLSC 484
           P++SQ  +  +  V+  ++ QQ    E E       +  VE    GQ +S     G L  
Sbjct: 23  PSSSQVDEEQMNRVVEEEQQQQLRQQEEEHTARNGEVVGVEPRPGGQNDS---QQGQLEE 79

Query: 485 DNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEF-S 543
           +N  F+      +  D +   EE+++  E A E+++E+EE+E+ +++S D D+++D    
Sbjct: 80  NNNRFI-----SVDEDSSGNQEEQEEDEEHAGEQDEEDEEEEEMDQESDDFDQSDDSSRE 134

Query: 544 DEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNEL 603
           DE    NS       +T+SS    L + QL   +      K    KR L    E +   L
Sbjct: 135 DEHTHTNS-------VTNSSSIVDLPVHQLSSPFYT----KTTKMKRKLDHGSEVRSFSL 183

Query: 604 LQKAVITPDFEKNHCVPPYS 623
            +K     ++     + P S
Sbjct: 184 GKKPCKVSEYTSTTGLVPCS 203


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 19/42 (45%), Positives = 30/42 (71%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           EEED+  E   EEE+E+EE+E+ EE+  + +E E+E  +EE+
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 19/42 (45%), Positives = 30/42 (71%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           EEE++  E   EEE+EEEE+E+ EE+  + +E E+E  +EE+
Sbjct: 264 EEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 19/42 (45%), Positives = 30/42 (71%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           EEE++  E   EEE+EEEE+E+ EE+  + +E E+E  +EE+
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/42 (42%), Positives = 30/42 (71%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           EEE++  E   E+E+EEEE+E+ EE+  + +E E+E  +EE+
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 18/42 (42%), Positives = 30/42 (71%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           EEE++  E   +EE+EEEE+E+ EE+  + +E E+E  +EE+
Sbjct: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 20/47 (42%), Positives = 30/47 (63%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNST 552
           EEED+  E   EEE+EEEE+E+ EE+  + +E E+E + +  F   T
Sbjct: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 19/50 (38%), Positives = 30/50 (60%)

Query: 498 SADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           S  K     EE+   E   EEE+EE+E+E+ EE+  + +E E+E  +EE+
Sbjct: 249 SKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/42 (42%), Positives = 29/42 (69%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           E+E++  E   EEE EEEE+E+ EE+  + +E E+E  +EE+
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 25/103 (24%), Positives = 52/103 (50%), Gaps = 2/103 (1%)

Query: 445 LSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFY 504
           L  + ++ + + E E+      E++ +   ++ +     C  +L   D     S+ +   
Sbjct: 197 LLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLE--DAASEESSKQKGI 254

Query: 505 LEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           L  E++  E   EEE+EEE++E+ EE+  + +E E+E  +EE+
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 17/42 (40%), Positives = 30/42 (71%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           EE+++  E   EEE++EEE+E+ EE+  + +E E+E  +EE+
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 17/42 (40%), Positives = 30/42 (71%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
           +EE++  E   EE++EEEE+E+ EE+  + +E E+E  +EE+
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 7/136 (5%)

Query: 426 LYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLC--FVENSGQRESLSGDTGSLS 483
           L  +A   +  +    L +   D  +  E +      LC   +E++   ES S   G LS
Sbjct: 198 LQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEES-SKQKGILS 256

Query: 484 CDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFS 543
            +      D       ++    EEE++  E   EEE+EEEE+E+ EE+  + +E   +  
Sbjct: 257 HEEE----DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312

Query: 544 DEEDFLNSTKAKLLKL 559
            +ED  +++  K  +L
Sbjct: 313 FQEDTSHTSAQKAPEL 328



 Score = 37.0 bits (84), Expect = 0.068
 Identities = 18/53 (33%), Positives = 31/53 (58%)

Query: 506 EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLK 558
           EEE++  E   EEE+EEEE+E+ EE+  +    +  F ++    ++ KA  L+
Sbjct: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELR 329


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 26/162 (16%)

Query: 393  DCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQ 452
            D GG +DE+ES    +SE+  S         T+    A    + +D+        D+S  
Sbjct: 1030 DSGGEEDEKES----LSEEQES---------TEEEEEAEEEEEEEDDD------DDDSDD 1070

Query: 453  SENSENEEDTLCFVE-------NSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYL 505
             + SEN+++     E       +S + E++S  T      ++    +++   S+ ++   
Sbjct: 1071 RDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPS 1130

Query: 506  EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEED 547
              ED+   VA EEE+EEEE+E   E+S      ED   D E+
Sbjct: 1131 SSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEE 1172



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 2/65 (3%)

Query: 491  IDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLN 550
            ++   G   D+   L EE +++E   E E+EEEE++  ++DS D DE+E++  DE+  L+
Sbjct: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESEND--DEDTALS 1084

Query: 551  STKAK 555
                K
Sbjct: 1085 EASEK 1089



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 50/244 (20%), Positives = 103/244 (42%), Gaps = 12/244 (4%)

Query: 282  EQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHST 341
            E+   ESL E +++ ++ +E      +E  + ++   + ++ ++ +DT+L +   +    
Sbjct: 1034 EEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGD 1093

Query: 342  PQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEE 401
               +  VS+ ++  +EA   S +   +  E    ++++ SP  + D  +       ++EE
Sbjct: 1094 SDEEETVSIVTS-KAEATSSSESSESSEFE----SSSESSPSSSEDEEEVVAREEEEEEE 1148

Query: 402  ESTVISVSEDMNSEGNVDFECDTKLYTSAPNT----SQGKDNSVLLVLSSDESQQSENSE 457
            E  +++  E M S G  DFE D +    AP      S G +  V +   +   ++  +  
Sbjct: 1149 EEEMVA-EESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSML 1207

Query: 458  NEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIE 517
            +E      VE          + G LS + A+ +    P    +    L  E +A E  +E
Sbjct: 1208 DEPPLPVGVEEPADSREPPEEPG-LSQEGAMLLSPEPPAKEVEARPPLSPE-RAPEHDLE 1265

Query: 518  EEKE 521
             E E
Sbjct: 1266 VEPE 1269



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 19/71 (26%)

Query: 506  EEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDE-------------FSDEEDFLNST 552
            EEE++A     EEE+EEE+D+  + D  D  EN+DE              SDEE+ ++  
Sbjct: 1049 EEEEEA-----EEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIV 1103

Query: 553  KAKLLKLTSSS 563
             +K  + TSSS
Sbjct: 1104 TSK-AEATSSS 1113



 Score = 35.4 bits (80), Expect = 0.20
 Identities = 17/55 (30%), Positives = 32/55 (58%), Gaps = 1/55 (1%)

Query: 507  EEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTS 561
            EED+   ++ E+E  EEE+E +EE+  + D+++D+  D ++  N  +   L   S
Sbjct: 1034 EEDEKESLSEEQESTEEEEE-AEEEEEEEDDDDDDSDDRDESENDDEDTALSEAS 1087


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 74/339 (21%), Positives = 124/339 (36%), Gaps = 59/339 (17%)

Query: 225  NEKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQA 284
            NEK    T   S   D      LQ+  L+++ + +F+              ++ T+H Q 
Sbjct: 4527 NEKAEENTDQASPQEDYAGFERLQSGHLTKLLEDDFW-------------ADVSTLHVQK 4573

Query: 285  NVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNL----SELQDTSLQQLVSQRHS 340
             + ++ E  +  K   ED  G   +    ++  S L  L    S   D  L  L     +
Sbjct: 4574 IISAISELLERLKSYGED--GTAAKHLFFSQSCSLLVRLVPVLSSYSDLVLFFLTMSLAT 4631

Query: 341  TPQNKNAVSVHSNLNSEAVMKS--LTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSD 398
                   +SV + + +E   K   L + F     G               T+F D  G  
Sbjct: 4632 HRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGE------------GATEFHDYEGGG 4679

Query: 399  DEEESTVISVSEDMNSEGNVD--FECDTKLYTSAPNTS---QGKDNSVLLVLSSD-ESQQ 452
              E   +  VS+ + +E  V+  F+   +     P++    +G+DN++ +    D +   
Sbjct: 4680 IGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHD 4739

Query: 453  SENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKAS 512
             E  E EED        G  +   GD      D              D+  + +++    
Sbjct: 4740 GELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKL------------DERLWGDDD---- 4783

Query: 513  EVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNS 551
                EEE EEEED K+EE     DE + E   ++D L+S
Sbjct: 4784 ----EEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDS 4818



 Score = 34.7 bits (78), Expect = 0.34
 Identities = 66/351 (18%), Positives = 129/351 (36%), Gaps = 38/351 (10%)

Query: 217  KDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSEN 276
            KD     GNE+Q+  T    ++ D          S S+I K      +  +DF  +  + 
Sbjct: 4687 KDVSDQIGNEEQVEDTFQKGQEKDKEDPD-----SKSDI-KGEDNAIEMSEDFDGKMHDG 4740

Query: 277  ILTVHEQANVESLKE-----------TKQNCKDLDEDANGITDEGKEINEKSSQLKNLSE 325
             L   E+ + +S  E             +    LDE   G  DE ++  E+ ++ +    
Sbjct: 4741 ELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGP 4800

Query: 326  LQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNN---NKKSP 382
              D    +LV++      + N  S +SN +     K   +  A  + G       N++  
Sbjct: 4801 GMDEEDSELVAK------DDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQID 4854

Query: 383  IKASDLTKFGDCGGSDDE-EESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSV 441
             +  D  +     G+ ++  E   + + +D+N       + + K      +  +G++ + 
Sbjct: 4855 ERDYDENEVDPYHGNQEKVPEPEALDLPDDLN------LDSEDKNGGEDTDNEEGEEENP 4908

Query: 442  LLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADK 501
            L +    E    E  E  E      E+   +E   G +     +    +         D 
Sbjct: 4909 LEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDA 4968

Query: 502  NFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSD-----HDENEDEFSDEED 547
              + EE  +  + ++EE+ +E ++E  E   +D      +E E E SD E+
Sbjct: 4969 AQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE 5019


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.122    0.324 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,211,232
Number of Sequences: 37866
Number of extensions: 1277299
Number of successful extensions: 22289
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 381
Number of HSP's successfully gapped in prelim test: 520
Number of HSP's that attempted gapping in prelim test: 9612
Number of HSP's gapped (non-prelim): 6108
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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