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Search of human proteins with 5453992
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453992 protein tyrosine phosphatase, non-receptor type 13
isoform 2 [Homo sapiens]
(2466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 4903 0.0
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 4892 0.0
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 4886 0.0
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 2820 0.0
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 367 e-101
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 367 e-101
gi|109138573 protein tyrosine phosphatase, non-receptor type 20A... 239 3e-62
gi|109138561 protein tyrosine phosphatase, non-receptor type 20A... 239 3e-62
gi|109138557 protein tyrosine phosphatase, non-receptor type 20A... 239 3e-62
gi|108802617 protein tyrosine phosphatase, non-receptor type 20 ... 239 3e-62
gi|108802607 protein tyrosine phosphatase, non-receptor type 20 ... 239 3e-62
gi|108802604 protein tyrosine phosphatase, non-receptor type 20 ... 239 3e-62
gi|108802611 protein tyrosine phosphatase, non-receptor type 20 ... 214 6e-55
gi|109138565 protein tyrosine phosphatase, non-receptor type 20A... 214 6e-55
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 194 1e-48
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 194 1e-48
gi|223941891 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941888 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941885 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941882 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941879 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|223941876 protein tyrosine phosphatase, non-receptor type 3 i... 190 2e-47
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [... 189 3e-47
gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Ho... 186 2e-46
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 183 2e-45
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 183 2e-45
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 182 4e-45
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is... 182 4e-45
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is... 182 4e-45
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is... 182 4e-45
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
2 [Homo sapiens]
Length = 2466
Score = 4903 bits (12719), Expect = 0.0
Identities = 2466/2466 (100%), Positives = 2466/2466 (100%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
Query: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
Query: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKD 1080
LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKD
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKD 1080
Query: 1081 AKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHA 1140
AKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHA
Sbjct: 1081 AKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHA 1140
Query: 1141 AIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHH 1200
AIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHH
Sbjct: 1141 AIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHH 1200
Query: 1201 WSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQH 1260
WSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQH
Sbjct: 1201 WSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQH 1260
Query: 1261 GSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQ 1320
GSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQ
Sbjct: 1261 GSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQ 1320
Query: 1321 ESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKA 1380
ESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKA
Sbjct: 1321 ESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKA 1380
Query: 1381 VIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKE 1440
VIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKE
Sbjct: 1381 VIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKE 1440
Query: 1441 HVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSRED 1500
HVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSRED
Sbjct: 1441 HVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSRED 1500
Query: 1501 NLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAP 1560
NLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAP
Sbjct: 1501 NLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAP 1560
Query: 1561 EVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKS 1620
EVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKS
Sbjct: 1561 EVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKS 1620
Query: 1621 KKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKS 1680
KKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKS
Sbjct: 1621 KKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPKS 1680
Query: 1681 QEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHIS 1740
QEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHIS
Sbjct: 1681 QEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHIS 1740
Query: 1741 EPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQ 1800
EPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQ
Sbjct: 1741 EPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQ 1800
Query: 1801 DPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPH 1860
DPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPH
Sbjct: 1801 DPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELPRIPMLPH 1860
Query: 1861 LLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVST 1920
LLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVST
Sbjct: 1861 LLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDVIHYVNGVST 1920
Query: 1921 QGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPA 1980
QGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPA
Sbjct: 1921 QGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNGSYSVGSCSQPA 1980
Query: 1981 LTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQ 2040
LTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQ
Sbjct: 1981 LTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQEDDIYDDSQEAEVIQ 2040
Query: 2041 SLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKM 2100
SLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKM
Sbjct: 2041 SLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTEDTDCDGSPLPEYFTEATKM 2100
Query: 2101 NGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELA 2160
NGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELA
Sbjct: 2101 NGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTNHEDSDKDHSFLTNDELA 2160
Query: 2161 VLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRR 2220
VLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRR
Sbjct: 2161 VLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRR 2220
Query: 2221 KNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWE 2280
KNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWE
Sbjct: 2221 KNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWE 2280
Query: 2281 QKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLED 2340
QKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLED
Sbjct: 2281 QKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLED 2340
Query: 2341 IQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLI 2400
IQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLI
Sbjct: 2341 IQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLI 2400
Query: 2401 CIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQ 2460
CIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQ
Sbjct: 2401 CIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRLQAEEEQKQ 2460
Query: 2461 QPQLLK 2466
QPQLLK
Sbjct: 2461 QPQLLK 2466
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 4892 bits (12689), Expect = 0.0
Identities = 2466/2485 (99%), Positives = 2466/2485 (99%), Gaps = 19/2485 (0%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
Query: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
Query: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL-------------------DVLHKR 1061
LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL DVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
Query: 1062 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1121
WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
Query: 1122 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1181
GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
Query: 1182 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1241
KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
Query: 1242 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1301
VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
Query: 1302 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1361
SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
Query: 1362 SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN 1421
SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN
Sbjct: 1381 SVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRN 1440
Query: 1422 TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF 1481
TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF
Sbjct: 1441 TGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTF 1500
Query: 1482 EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA 1541
EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA
Sbjct: 1501 EVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGA 1560
Query: 1542 SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ 1601
SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ
Sbjct: 1561 SLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQ 1620
Query: 1602 PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH 1661
PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH
Sbjct: 1621 PSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALH 1680
Query: 1662 QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP 1721
QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP
Sbjct: 1681 QTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQP 1740
Query: 1722 QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG 1781
QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG
Sbjct: 1741 QSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLG 1800
Query: 1782 FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT 1841
FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT
Sbjct: 1801 FTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKT 1860
Query: 1842 VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA 1901
VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA
Sbjct: 1861 VRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAA 1920
Query: 1902 IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA 1961
IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA
Sbjct: 1921 IEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSA 1980
Query: 1962 PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE 2021
PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE
Sbjct: 1981 PKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKE 2040
Query: 2022 SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE 2081
SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE
Sbjct: 2041 SYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTE 2100
Query: 2082 DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER 2141
DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER
Sbjct: 2101 DTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIER 2160
Query: 2142 TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL 2201
TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL
Sbjct: 2161 TNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL 2220
Query: 2202 QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI 2261
QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI
Sbjct: 2221 QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYI 2280
Query: 2262 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2321
ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA
Sbjct: 2281 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2340
Query: 2322 LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR 2381
LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR
Sbjct: 2341 LVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR 2400
Query: 2382 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2441
SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC
Sbjct: 2401 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2460
Query: 2442 YQVILYVLTRLQAEEEQKQQPQLLK 2466
YQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2461 YQVILYVLTRLQAEEEQKQQPQLLK 2485
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 4886 bits (12673), Expect = 0.0
Identities = 2466/2490 (99%), Positives = 2466/2490 (99%), Gaps = 24/2490 (0%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQAESVRG 900
Query: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE
Sbjct: 901 FNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWE 960
Query: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK
Sbjct: 961 EKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAGVTK 1020
Query: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL-------------------DVLHKR 1061
LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVL DVLHKR
Sbjct: 1021 LNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVPLKENDVLHKR 1080
Query: 1062 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1121
WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP
Sbjct: 1081 WSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKP 1140
Query: 1122 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1181
GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM
Sbjct: 1141 GDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYM 1200
Query: 1182 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1241
KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ
Sbjct: 1201 KKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTESASLSQSQ 1260
Query: 1242 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1301
VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD
Sbjct: 1261 VNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGD 1320
Query: 1302 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1361
SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI
Sbjct: 1321 SDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGI 1380
Query: 1362 SVT-----GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1416
SVT GGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV
Sbjct: 1381 SVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAV 1440
Query: 1417 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1476
ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT
Sbjct: 1441 ETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSFVT 1500
Query: 1477 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1536
EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL
Sbjct: 1501 EENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVIL 1560
Query: 1537 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1596
KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS
Sbjct: 1561 KVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSS 1620
Query: 1597 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1656
KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW
Sbjct: 1621 KDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTW 1680
Query: 1657 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1716
SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG
Sbjct: 1681 SSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPG 1740
Query: 1717 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1776
QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE
Sbjct: 1741 QSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSE 1800
Query: 1777 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1836
KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR
Sbjct: 1801 KGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
Query: 1837 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1896
AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP
Sbjct: 1861 AASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINP 1920
Query: 1897 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1956
RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR
Sbjct: 1921 RSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKR 1980
Query: 1957 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2016
SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL
Sbjct: 1981 SAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNL 2040
Query: 2017 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2076
TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS
Sbjct: 2041 TLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLS 2100
Query: 2077 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2136
EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE
Sbjct: 2101 EERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDE 2160
Query: 2137 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2196
LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK
Sbjct: 2161 LPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK 2220
Query: 2197 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2256
ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE
Sbjct: 2221 ELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKE 2280
Query: 2257 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2316
EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN
Sbjct: 2281 EFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSN 2340
Query: 2317 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2376
RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM
Sbjct: 2341 RLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYM 2400
Query: 2377 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2436
RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED
Sbjct: 2401 RHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTED 2460
Query: 2437 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2466
QYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2461 QYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2490
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 2820 bits (7311), Expect = 0.0
Identities = 1411/1412 (99%), Positives = 1412/1412 (100%)
Query: 1055 LDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPAD 1114
+DVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPAD
Sbjct: 883 IDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPAD 942
Query: 1115 LDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLT 1174
LDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLT
Sbjct: 943 LDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLT 1002
Query: 1175 NEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTES 1234
NEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTES
Sbjct: 1003 NEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFGPSGGLREGSLSSQDSRTES 1062
Query: 1235 ASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVT 1294
ASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVT
Sbjct: 1063 ASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVT 1122
Query: 1295 DYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAK 1354
DYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAK
Sbjct: 1123 DYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAK 1182
Query: 1355 NDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQ 1414
NDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQ
Sbjct: 1183 NDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQ 1242
Query: 1415 AVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSF 1474
AVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSF
Sbjct: 1243 AVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKDYSF 1302
Query: 1475 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1534
VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV
Sbjct: 1303 VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDV 1362
Query: 1535 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1594
ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN
Sbjct: 1363 ILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPN 1422
Query: 1595 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNS 1654
SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNS
Sbjct: 1423 SSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVTAPANISNS 1482
Query: 1655 TWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMA 1714
TWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMA
Sbjct: 1483 TWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMA 1542
Query: 1715 PGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIK 1774
PGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIK
Sbjct: 1543 PGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIK 1602
Query: 1775 SEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNL 1834
SEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNL
Sbjct: 1603 SEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNL 1662
Query: 1835 LRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDI 1894
LRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDI
Sbjct: 1663 LRAASKTVRLVIGRVLELPRIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDI 1722
Query: 1895 NPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSS 1954
NPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSS
Sbjct: 1723 NPRSVAAIEGNLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSS 1782
Query: 1955 KRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSP 2014
KRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSP
Sbjct: 1783 KRSAVSAPKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSP 1842
Query: 2015 NLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGK 2074
NLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGK
Sbjct: 1843 NLTLPKESYIQEDDIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGK 1902
Query: 2075 LSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGN 2134
LSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGN
Sbjct: 1903 LSEERTEDTDCDGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGN 1962
Query: 2135 DELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIP 2194
DELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIP
Sbjct: 1963 DELPIERTNHEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIP 2022
Query: 2195 SKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVG 2254
SKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVG
Sbjct: 2023 SKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVG 2082
Query: 2255 KEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMV 2314
KEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMV
Sbjct: 2083 KEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMV 2142
Query: 2315 SNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFIS 2374
SNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFIS
Sbjct: 2143 SNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFIS 2202
Query: 2375 YMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQT 2434
YMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQT
Sbjct: 2203 YMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQT 2262
Query: 2435 EDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2466
EDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK
Sbjct: 2263 EDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK 2294
Score = 1796 bits (4653), Expect = 0.0
Identities = 967/1278 (75%), Positives = 1029/1278 (80%), Gaps = 112/1278 (8%)
Query: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP
Sbjct: 1 MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLP 60
Query: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ
Sbjct: 61 SGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQ 120
Query: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL
Sbjct: 121 PIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNCAPSFSYVKHLVKLVLGNL 180
Query: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS
Sbjct: 181 SGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTGRSSTSDVLDIQKPPLSHQTFLNKGLSKS 240
Query: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA
Sbjct: 241 MGFLSIKDTQDENYFKDILSDNSGREDSENTFSPYQFKTSGPEKKPIPGIDVLSKKKIWA 300
Query: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD
Sbjct: 301 SSMDLLCTADRDFSSGETATYRRCHPEAVTVRTSTTPRKKEARYSDGSIALDIFGPQKMD 360
Query: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS
Sbjct: 361 PIYHTRELPTSSAISSALDRIRERQKKLQVLREAMNVEEPVRRYKTYHGDVFSTSSESPS 420
Query: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML
Sbjct: 421 IISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSRQYETPFEGNLINQEIML 480
Query: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG
Sbjct: 481 KRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPLREIALETAMTQRKLRNFFG 540
Query: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM
Sbjct: 541 PEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDVFDM 600
Query: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI
Sbjct: 601 VVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLFFRI 660
Query: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG
Sbjct: 661 KFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPEVHG 720
Query: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF
Sbjct: 721 VSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHF 780
Query: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD
Sbjct: 781 HRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITLQNTSD 840
Query: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIE------------RASF 888
GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI+
Sbjct: 841 GIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIDVLHKRWSIVSSPEREI 900
Query: 889 RSLNLQAES--------VRGFNMGRAISTGSLASS--------------------TLNKL 920
+NL+ ++ + G MGR + G SS ++N +
Sbjct: 901 TLVNLKKDAKYGLGFQIIGGEKMGR-LDLGIFISSVAPGGPADLDGCLKPGDRLISVNSV 959
Query: 921 AVRPLSVQAEILKRLSCSE---LSLYQPLQNSSKE-------KNDKASWEEKPREMSKSY 970
++ +S A I + E L + QP + SK N+ ++ +K M S
Sbjct: 960 SLEGVSHHAAIEILQNAPEDVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSA 1019
Query: 971 HDLSQASLYPHR---KNVIVNMEPPPQTVAELVGKPSHQMSRSDAESLAG---------- 1017
D S + R +++ N P + E G S Q SR+++ SL+
Sbjct: 1020 IDSSSKDHHWSRGTLRHISENSFGPSGGLRE--GSLSSQDSRTESASLSQSQVNGFFASH 1077
Query: 1018 ------------------VTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLH 1059
++K ++ N+S ++ SD + D G + + + +
Sbjct: 1078 LGDQTWQESQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATY 1137
Query: 1060 KRWSIVSSPERE-------------------------ITLVNLKKDAKYGLGFQIIGGEK 1094
+P++E I V L K+ LG + GG
Sbjct: 1138 SSSQDHQTPKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDN-SLGISVTGGVN 1196
Query: 1095 MGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTL 1154
GI++ +V P G A+ DG + GDR+++VN VSLEG +H A+E L+N + V L
Sbjct: 1197 TSVRHGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHL 1256
Query: 1155 VISQPKEKISK--VPSTP 1170
++ + + SK VP TP
Sbjct: 1257 LLEKGQSPTSKEHVPVTP 1274
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 367 bits (943), Expect = e-101
Identities = 229/626 (36%), Positives = 348/626 (55%), Gaps = 75/626 (11%)
Query: 538 FFGPEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDV 597
F PEF+ + E ++L LP S++TKKGK+ R + ++LLNGQ LE+ CD ++ V
Sbjct: 286 FSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAV 345
Query: 598 FDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLF 657
F+ V + L E F LA +K E+FF+D + +L K+APEGW+E+P+K + T FTLF
Sbjct: 346 FNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNT--FTLF 403
Query: 658 FRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPE 717
RIKFF+ L+QH+LT HQ+YLQLRKDILEER++C++E L L LALQAE+G+Y E
Sbjct: 404 LRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKE 463
Query: 718 -VHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEY 776
V YF +E Y+PA ++E++ ++ E+ ++H ++ EL+FL+V Q+L EY
Sbjct: 464 QVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEY 523
Query: 777 GVHFHRVHPEK-KSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITL 835
GV H+V EK + + + LG+C+KGV+V+EV N R +LRF WRET KIS +KK T+
Sbjct: 524 GVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTI 583
Query: 836 QNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQA 895
++ G KH F TD++K +YLL LCS QH F QM + Q +
Sbjct: 584 TSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQPSHVL--------------- 628
Query: 896 ESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLY-QPLQNSSKEKN 954
F+ + + +L S ++ +PL ++RLSCSE L+ LQ ++
Sbjct: 629 -----FDHDKFVQMANL--SPAHQARSKPLI----WIQRLSCSENELFVSRLQGAAGGL- 676
Query: 955 DKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAES 1014
+S S + N++ + AE +G+ + E
Sbjct: 677 -----------LSTSMDNF--------------NVDGSKEAGAEGIGR----SPCTGREQ 707
Query: 1015 LAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITL 1074
L + + SL+ P + H + ++R S ++ P REI
Sbjct: 708 LKSACVIQKPMTWDSLSGPPVQSMHAGSKN--------------NRRKSFIAEPGREIVR 753
Query: 1075 VNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLE 1134
V LK+D G GF I GE G+ D GIFISS+ PGGPA+ +KPG +++++N +SLE
Sbjct: 754 VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 813
Query: 1135 GVSHHAAIEILQNAPEDVTLVISQPK 1160
G + + A+ ++QN+P+++ L+ISQ K
Sbjct: 814 GFTFNMAVRMIQNSPDNIELIISQSK 839
Score = 220 bits (561), Expect = 1e-56
Identities = 144/381 (37%), Positives = 205/381 (53%), Gaps = 48/381 (12%)
Query: 1279 DSNQSKTKKPGIS--DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKT 1336
D ++ T G+S D+ + +G +++ QD T + + + + ++ +
Sbjct: 847 DEEKNSTANSGVSSTDILSFGYQGSL----LSHTQDQDRNTEELDMAGVQSLVPRLRHQL 902
Query: 1337 F--------SSSPPKP-----GDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIP 1383
SS PP P G+I+ VEL K D +LG SVTGG+NTSV +GGIYVK+++P
Sbjct: 903 SFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVP 962
Query: 1384 QGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVP 1443
G A +G+I +GDR+L V+GV L G THKQAV+ L GQV L+LE+ VP
Sbjct: 963 GGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLER--------RVP 1014
Query: 1444 VTPQCTLSDQNAQGQGPEKVKKTTQV----KDYSFVTEENTFEVKLFKNSSGLGFSFSRE 1499
+ Q S ++ G V T + VT+ FEVKL KN++GLGFSF +
Sbjct: 1015 RSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQM 1074
Query: 1500 DNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTA 1559
+ + + +VR+K+LFPGQPA E+G I GD+IL VNG S +GL QEV+ LRG
Sbjct: 1075 EKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAP 1134
Query: 1560 PEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDK 1619
EV LLLCRPPPG LPE++ TP S + K+ ++ +C + TS ++
Sbjct: 1135 QEVTLLLCRPPPGALPELEQEWQTPELS-------ADKEFTRATCTDSCTSPILDQ---- 1183
Query: 1620 SKKQCKSPSRRDSYSDSSGSG 1640
S RDS S +G G
Sbjct: 1184 ------EDSWRDSASPDAGEG 1198
Score = 108 bits (271), Expect = 5e-23
Identities = 76/208 (36%), Positives = 115/208 (55%), Gaps = 33/208 (15%)
Query: 3 VSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLPSG 62
V+LA AL+VRG L EEEIW++L +AE L E R S +++ PWS LL +G
Sbjct: 15 VTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSS------DYVVCPWSALLSAAG 68
Query: 63 SVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQPI 122
S+SF +S+ + F APE+LQ QS D + SQP+
Sbjct: 69 SLSFQGR-VSHIEAAPFKAPELLQGQS----------------------EDEQPDASQPL 105
Query: 123 KLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNC--APSFSYVKHLVKLVLGNL 180
+L + L+SILL MCED + R ++++VL+AC H + + AP+ +++ LV LVLG +
Sbjct: 106 QLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTI 165
Query: 181 SGTDQ--LSCNSEQKPDRSQAIRDRLRG 206
S ++ + +S + +RS +R RLRG
Sbjct: 166 SEVEKRVVEESSSVQQNRSYLLRKRLRG 193
Score = 74.3 bits (181), Expect = 1e-12
Identities = 75/294 (25%), Positives = 127/294 (43%), Gaps = 56/294 (19%)
Query: 1325 SVNTSNKMNF-KTFSSSPPKPGDIFEVELAKNDN-SLGISVTGGVNTSVRHGGIYVKAVI 1382
S++ +K N K+F + P + +I V L ++ + G + G + GI++ ++I
Sbjct: 730 SMHAGSKNNRRKSFIAEPGR--EIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSII 787
Query: 1383 PQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK-----GQSP- 1436
P G AE I G ++LA+N +SLEG T AV ++N+ + L++ + G +P
Sbjct: 788 PGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVGGNNPD 847
Query: 1437 -----TSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD--------------YSF--- 1474
T+ V T + Q + + + T+ D SF
Sbjct: 848 EEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPL 907
Query: 1475 -------------VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASI----VRVKKL 1517
++ + V+L K LGFS + IN S+ + VK +
Sbjct: 908 KGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFS-------VTGGINTSVPYGGIYVKSI 960
Query: 1518 FPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP 1571
PG PAA+ G+I GD +L+V+G L GL+ ++ + L G L+L R P
Sbjct: 961 VPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1014
Score = 60.8 bits (146), Expect = 2e-08
Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 50/277 (18%)
Query: 1767 ELLITLIKSEKGSLGFTVTKG-NQRI---GCYVHDVIQD-PAKSDGRLKPGDRLIKVNDT 1821
E+ + E G+LGF+VT G N + G YV ++ PA +G++ GDRL++V+
Sbjct: 925 EIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 984
Query: 1822 DVTNMTHTDAVNLLRAASKTVRLVIGR-------------------------VLELPRIP 1856
+ +TH AV L + RLV+ R V LP P
Sbjct: 985 ILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRP 1044
Query: 1857 MLPHLLPD-----ITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEG 1904
+ D + L N LGFS C S +V I + P A G
Sbjct: 1045 SSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENG 1102
Query: 1905 NLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVS 1960
+ D+I VNG ST+G+ +EV L + + L R +P ++ +S
Sbjct: 1103 AIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS 1162
Query: 1961 APKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINE 1997
A K + + SC+ P L DS+ A + E
Sbjct: 1163 ADK--EFTRATCTDSCTSPILDQEDSWRDSASPDAGE 1197
Score = 57.0 bits (136), Expect = 2e-07
Identities = 42/132 (31%), Positives = 69/132 (52%), Gaps = 6/132 (4%)
Query: 1032 RSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIG 1091
RS ++ +DS E + V + + S VS + V LKK+A GLGF +
Sbjct: 1015 RSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNAN-GLGFSFVQ 1073
Query: 1092 GEKMG----RLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQN 1147
EK + DL + I + PG PA+ +G + GD +++VN S EG+ + +L+
Sbjct: 1074 MEKESCSHLKSDL-VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRG 1132
Query: 1148 APEDVTLVISQP 1159
AP++VTL++ +P
Sbjct: 1133 APQEVTLLLCRP 1144
Score = 55.1 bits (131), Expect = 9e-07
Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 10/142 (7%)
Query: 1026 SVASLNRSPERRKHESDSSSIED--PGQAYVLDVLHKRWSIVSSPER-------EITLVN 1076
S+ S + +R E D + ++ P + L L + + S P EI V
Sbjct: 871 SLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPLKGAGSSCPPSPPEISAGEIYFVE 930
Query: 1077 LKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGV 1136
L K+ LGF + GG GI++ S+ PGGPA +G + GDRL+ V+ V L G+
Sbjct: 931 LVKEDGT-LGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGVILCGL 989
Query: 1137 SHHAAIEILQNAPEDVTLVISQ 1158
+H A++ L + LV+ +
Sbjct: 990 THKQAVQCLTGPGQVARLVLER 1011
Score = 32.7 bits (73), Expect = 4.5
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 1770 ITLIKSEKGSLGFTVTKGNQR----IGCYVHDVIQD-PAKSDGRLKPGDRLIKVNDTDVT 1824
+TL + GF + +G G ++ +I PA+ +KPG +++ +N +
Sbjct: 754 VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 813
Query: 1825 NMTHTDAVNLLRAASKTVRLVIGR 1848
T AV +++ + + L+I +
Sbjct: 814 GFTFNMAVRMIQNSPDNIELIISQ 837
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 367 bits (943), Expect = e-101
Identities = 229/626 (36%), Positives = 348/626 (55%), Gaps = 75/626 (11%)
Query: 538 FFGPEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLLNGQRLELTCDTKTICKDV 597
F PEF+ + E ++L LP S++TKKGK+ R + ++LLNGQ LE+ CD ++ V
Sbjct: 308 FSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAV 367
Query: 598 FDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPKKKTKATVNFTLF 657
F+ V + L E F LA +K E+FF+D + +L K+APEGW+E+P+K + T FTLF
Sbjct: 368 FNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNT--FTLF 425
Query: 658 FRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGDYQPE 717
RIKFF+ L+QH+LT HQ+YLQLRKDILEER++C++E L L LALQAE+G+Y E
Sbjct: 426 LRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKE 485
Query: 718 -VHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRLTEY 776
V YF +E Y+PA ++E++ ++ E+ ++H ++ EL+FL+V Q+L EY
Sbjct: 486 QVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEY 545
Query: 777 GVHFHRVHPEK-KSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKITL 835
GV H+V EK + + + LG+C+KGV+V+EV N R +LRF WRET KIS +KK T+
Sbjct: 546 GVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTI 605
Query: 836 QNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDIERASFRSLNLQA 895
++ G KH F TD++K +YLL LCS QH F QM + Q +
Sbjct: 606 TSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQPSHVL--------------- 650
Query: 896 ESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSELSLY-QPLQNSSKEKN 954
F+ + + +L S ++ +PL ++RLSCSE L+ LQ ++
Sbjct: 651 -----FDHDKFVQMANL--SPAHQARSKPLI----WIQRLSCSENELFVSRLQGAAGGL- 698
Query: 955 DKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQMSRSDAES 1014
+S S + N++ + AE +G+ + E
Sbjct: 699 -----------LSTSMDNF--------------NVDGSKEAGAEGIGR----SPCTGREQ 729
Query: 1015 LAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITL 1074
L + + SL+ P + H + ++R S ++ P REI
Sbjct: 730 LKSACVIQKPMTWDSLSGPPVQSMHAGSKN--------------NRRKSFIAEPGREIVR 775
Query: 1075 VNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLE 1134
V LK+D G GF I GE G+ D GIFISS+ PGGPA+ +KPG +++++N +SLE
Sbjct: 776 VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 835
Query: 1135 GVSHHAAIEILQNAPEDVTLVISQPK 1160
G + + A+ ++QN+P+++ L+ISQ K
Sbjct: 836 GFTFNMAVRMIQNSPDNIELIISQSK 861
Score = 220 bits (561), Expect = 1e-56
Identities = 144/381 (37%), Positives = 205/381 (53%), Gaps = 48/381 (12%)
Query: 1279 DSNQSKTKKPGIS--DVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNKMNFKT 1336
D ++ T G+S D+ + +G +++ QD T + + + + ++ +
Sbjct: 869 DEEKNSTANSGVSSTDILSFGYQGSL----LSHTQDQDRNTEELDMAGVQSLVPRLRHQL 924
Query: 1337 F--------SSSPPKP-----GDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIP 1383
SS PP P G+I+ VEL K D +LG SVTGG+NTSV +GGIYVK+++P
Sbjct: 925 SFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVP 984
Query: 1384 QGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVP 1443
G A +G+I +GDR+L V+GV L G THKQAV+ L GQV L+LE+ VP
Sbjct: 985 GGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLER--------RVP 1036
Query: 1444 VTPQCTLSDQNAQGQGPEKVKKTTQV----KDYSFVTEENTFEVKLFKNSSGLGFSFSRE 1499
+ Q S ++ G V T + VT+ FEVKL KN++GLGFSF +
Sbjct: 1037 RSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQM 1096
Query: 1500 DNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTA 1559
+ + + +VR+K+LFPGQPA E+G I GD+IL VNG S +GL QEV+ LRG
Sbjct: 1097 EKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAP 1156
Query: 1560 PEVFLLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDK 1619
EV LLLCRPPPG LPE++ TP S + K+ ++ +C + TS ++
Sbjct: 1157 QEVTLLLCRPPPGALPELEQEWQTPELS-------ADKEFTRATCTDSCTSPILDQ---- 1205
Query: 1620 SKKQCKSPSRRDSYSDSSGSG 1640
S RDS S +G G
Sbjct: 1206 ------EDSWRDSASPDAGEG 1220
Score = 150 bits (379), Expect = 1e-35
Identities = 88/208 (42%), Positives = 130/208 (62%), Gaps = 11/208 (5%)
Query: 3 VSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADPAALGFIISPWSLLLLPSG 62
V+LA AL+VRG L EEEIW++L +AE L E R S +++ PWS LL +G
Sbjct: 15 VTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSS------DYVVCPWSALLSAAG 68
Query: 63 SVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIYSLGMTLYWGADYEVPQSQPI 122
S+SF +S+ + F APE+LQ QS D ++H+YSLGMTLYW A + VP QP+
Sbjct: 69 SLSFQGR-VSHIEAAPFKAPELLQGQSEDEQPDASQMHVYSLGMTLYWSAGFHVPPHQPL 127
Query: 123 KLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNSNC--APSFSYVKHLVKLVLGNL 180
+L + L+SILL MCED + R ++++VL+AC H + + AP+ +++ LV LVLG +
Sbjct: 128 QLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTI 187
Query: 181 SGTDQ--LSCNSEQKPDRSQAIRDRLRG 206
S ++ + +S + +RS +R RLRG
Sbjct: 188 SEVEKRVVEESSSVQQNRSYLLRKRLRG 215
Score = 74.3 bits (181), Expect = 1e-12
Identities = 75/294 (25%), Positives = 127/294 (43%), Gaps = 56/294 (19%)
Query: 1325 SVNTSNKMNF-KTFSSSPPKPGDIFEVELAKNDN-SLGISVTGGVNTSVRHGGIYVKAVI 1382
S++ +K N K+F + P + +I V L ++ + G + G + GI++ ++I
Sbjct: 752 SMHAGSKNNRRKSFIAEPGR--EIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSII 809
Query: 1383 PQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK-----GQSP- 1436
P G AE I G ++LA+N +SLEG T AV ++N+ + L++ + G +P
Sbjct: 810 PGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVGGNNPD 869
Query: 1437 -----TSKEHVPVTPQCTLSDQNAQGQGPEKVKKTTQVKD--------------YSF--- 1474
T+ V T + Q + + + T+ D SF
Sbjct: 870 EEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPL 929
Query: 1475 -------------VTEENTFEVKLFKNSSGLGFSFSREDNLIPEQINASI----VRVKKL 1517
++ + V+L K LGFS + IN S+ + VK +
Sbjct: 930 KGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFS-------VTGGINTSVPYGGIYVKSI 982
Query: 1518 FPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVFLLLCRPPP 1571
PG PAA+ G+I GD +L+V+G L GL+ ++ + L G L+L R P
Sbjct: 983 VPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVP 1036
Score = 60.8 bits (146), Expect = 2e-08
Identities = 73/277 (26%), Positives = 110/277 (39%), Gaps = 50/277 (18%)
Query: 1767 ELLITLIKSEKGSLGFTVTKG-NQRI---GCYVHDVIQD-PAKSDGRLKPGDRLIKVNDT 1821
E+ + E G+LGF+VT G N + G YV ++ PA +G++ GDRL++V+
Sbjct: 947 EIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 1006
Query: 1822 DVTNMTHTDAVNLLRAASKTVRLVIGR-------------------------VLELPRIP 1856
+ +TH AV L + RLV+ R V LP P
Sbjct: 1007 ILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCPSANDSMGDERTAVSLVTALPGRP 1066
Query: 1857 MLPHLLPD-----ITLTCNKEELGFSL-------CGGHDSLYQVVYISDINPRSVAAIEG 1904
+ D + L N LGFS C S +V I + P A G
Sbjct: 1067 SSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKS--DLVRIKRLFPGQPAEENG 1124
Query: 1905 NLQLLDVIHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRS----AVS 1960
+ D+I VNG ST+G+ +EV L + + L R +P ++ +S
Sbjct: 1125 AIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELS 1184
Query: 1961 APKSTKGNGSYSVGSCSQPALTPNDSFSTVAGEEINE 1997
A K + + SC+ P L DS+ A + E
Sbjct: 1185 ADK--EFTRATCTDSCTSPILDQEDSWRDSASPDAGE 1219
Score = 57.0 bits (136), Expect = 2e-07
Identities = 42/132 (31%), Positives = 69/132 (52%), Gaps = 6/132 (4%)
Query: 1032 RSPERRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIG 1091
RS ++ +DS E + V + + S VS + V LKK+A GLGF +
Sbjct: 1037 RSTQQCPSANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNAN-GLGFSFVQ 1095
Query: 1092 GEKMG----RLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQN 1147
EK + DL + I + PG PA+ +G + GD +++VN S EG+ + +L+
Sbjct: 1096 MEKESCSHLKSDL-VRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRG 1154
Query: 1148 APEDVTLVISQP 1159
AP++VTL++ +P
Sbjct: 1155 APQEVTLLLCRP 1166
Score = 55.1 bits (131), Expect = 9e-07
Identities = 42/142 (29%), Positives = 67/142 (47%), Gaps = 10/142 (7%)
Query: 1026 SVASLNRSPERRKHESDSSSIED--PGQAYVLDVLHKRWSIVSSPER-------EITLVN 1076
S+ S + +R E D + ++ P + L L + + S P EI V
Sbjct: 893 SLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPLKGAGSSCPPSPPEISAGEIYFVE 952
Query: 1077 LKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGV 1136
L K+ LGF + GG GI++ S+ PGGPA +G + GDRL+ V+ V L G+
Sbjct: 953 LVKEDGT-LGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGVILCGL 1011
Query: 1137 SHHAAIEILQNAPEDVTLVISQ 1158
+H A++ L + LV+ +
Sbjct: 1012 THKQAVQCLTGPGQVARLVLER 1033
Score = 32.7 bits (73), Expect = 4.5
Identities = 18/84 (21%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 1770 ITLIKSEKGSLGFTVTKGNQR----IGCYVHDVIQD-PAKSDGRLKPGDRLIKVNDTDVT 1824
+TL + GF + +G G ++ +I PA+ +KPG +++ +N +
Sbjct: 776 VTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLE 835
Query: 1825 NMTHTDAVNLLRAASKTVRLVIGR 1848
T AV +++ + + L+I +
Sbjct: 836 GFTFNMAVRMIQNSPDNIELIISQ 859
>gi|109138573 protein tyrosine phosphatase, non-receptor type 20A
isoform 8 [Homo sapiens]
Length = 339
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 97 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 156
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 157 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 215
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2392
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 216 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 275
Query: 2393 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 276 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 335
>gi|109138561 protein tyrosine phosphatase, non-receptor type 20A
isoform 3 [Homo sapiens]
Length = 411
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 169 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 228
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 229 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 287
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2392
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 288 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 347
Query: 2393 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 348 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 407
>gi|109138557 protein tyrosine phosphatase, non-receptor type 20A
isoform 1 [Homo sapiens]
Length = 420
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 178 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 237
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 238 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 296
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2392
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 297 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 356
Query: 2393 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 357 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 416
>gi|108802617 protein tyrosine phosphatase, non-receptor type 20
isoform 8 [Homo sapiens]
Length = 339
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 97 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 156
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 157 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 215
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2392
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 216 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 275
Query: 2393 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 276 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 335
>gi|108802607 protein tyrosine phosphatase, non-receptor type 20
isoform 3 [Homo sapiens]
Length = 411
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 169 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 228
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 229 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 287
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2392
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 288 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 347
Query: 2393 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 348 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 407
>gi|108802604 protein tyrosine phosphatase, non-receptor type 20
isoform 1 [Homo sapiens]
Length = 420
Score = 239 bits (609), Expect = 3e-62
Identities = 117/240 (48%), Positives = 156/240 (65%), Gaps = 1/240 (0%)
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
G NR KNRY++ILPYD+TRVPLG YINAS+I+I EE+ YIA QGPL +T+
Sbjct: 178 GNQPSNREKNRYRDILPYDSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTID 237
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFWQM+ E S VIAM+T+E+EG IKC YWP L K + + R+ L Q L+ F+
Sbjct: 238 DFWQMVLENNSNVIAMITREIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFI 296
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAG 2392
+R + + T + L FT WPDH TP+ D + +I Y R H +GP++ HCSAG
Sbjct: 297 IRMFQVVEKSTGTSHSVKQLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAG 356
Query: 2393 IGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
IGR+G +C+DVV I ++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 357 IGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 416
>gi|108802611 protein tyrosine phosphatase, non-receptor type 20
isoform 5 [Homo sapiens]
Length = 228
Score = 214 bits (546), Expect = 6e-55
Identities = 106/222 (47%), Positives = 143/222 (64%), Gaps = 1/222 (0%)
Query: 2231 DATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT 2290
D+TRVPLG YINAS+I+I EE+ YIA QGPL +T+ DFWQM+ E S VIAM+T
Sbjct: 4 DSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMIT 63
Query: 2291 QEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHIS 2350
+E+EG IKC YWP L K + + R+ L Q L+ F++R + + T +
Sbjct: 64 REIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVK 122
Query: 2351 HLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLIS 2410
L FT WPDH TP+ D + +I Y R H +GP++ HCSAGIGR+G +C+DVV I
Sbjct: 123 QLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIV 182
Query: 2411 QDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 183 KNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 224
>gi|109138565 protein tyrosine phosphatase, non-receptor type 20A
isoform 5 [Homo sapiens]
Length = 228
Score = 214 bits (546), Expect = 6e-55
Identities = 106/222 (47%), Positives = 143/222 (64%), Gaps = 1/222 (0%)
Query: 2231 DATRVPLGDEGGYINASFIKIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMT 2290
D+TRVPLG YINAS+I+I EE+ YIA QGPL +T+ DFWQM+ E S VIAM+T
Sbjct: 4 DSTRVPLGKSKDYINASYIRIVNCGEEYFYIATQGPLLSTIDDFWQMVLENNSNVIAMIT 63
Query: 2291 QEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHIS 2350
+E+EG IKC YWP L K + + R+ L Q L+ F++R + + T +
Sbjct: 64 REIEGGIIKCYHYWPISLKKPLELKH-FRVFLENYQILQYFIIRMFQVVEKSTGTSHSVK 122
Query: 2351 HLNFTAWPDHDTPSQPDDLLTFISYMRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLIS 2410
L FT WPDH TP+ D + +I Y R H +GP++ HCSAGIGR+G +C+DVV I
Sbjct: 123 QLQFTKWPDHGTPASADSFIKYIRYARKSHLTGPMVVHCSAGIGRTGVFLCVDVVFCAIV 182
Query: 2411 QDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLTRL 2452
++ F+I D+V MR QR GMVQT++QY FCY ++L VL +L
Sbjct: 183 KNCSFNIMDIVAQMREQRSGMVQTKEQYHFCYDIVLEVLRKL 224
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform 2
precursor [Homo sapiens]
Length = 937
Score = 194 bits (492), Expect = 1e-48
Identities = 107/261 (40%), Positives = 150/261 (57%), Gaps = 13/261 (4%)
Query: 2211 LIGQTKENRRKNRYKNILPYDATRVPLG---DEGG--YINASFIKIPVGKEEFVYIACQG 2265
++ EN KNRY+N+LPYD +RVPL +E G YINASF+ +EF IA QG
Sbjct: 659 MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEF--IATQG 716
Query: 2266 PLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRM 2325
PLP TVGDFW+++WEQ+S + M+T +E ++KC+ YWP L LR+ LV
Sbjct: 717 PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP--LDSQPCTHGHLRVTLVGE 774
Query: 2326 QQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHR 2381
+ ++ + VR + L ++ ++ + ++ AWPDH PS PD LL F +R
Sbjct: 775 EVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTME 834
Query: 2382 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2441
GP I HCSAG+GR+GTLI +DV+L + + VR MR R MVQTE QY+F
Sbjct: 835 GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFL 894
Query: 2442 YQVILYVLTRLQAEEEQKQQP 2462
+Q IL L + +K+ P
Sbjct: 895 HQCILRFLQQSAQAPAEKEVP 915
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 194 bits (492), Expect = 1e-48
Identities = 107/261 (40%), Positives = 150/261 (57%), Gaps = 13/261 (4%)
Query: 2211 LIGQTKENRRKNRYKNILPYDATRVPLG---DEGG--YINASFIKIPVGKEEFVYIACQG 2265
++ EN KNRY+N+LPYD +RVPL +E G YINASF+ +EF IA QG
Sbjct: 837 MVASASENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEF--IATQG 894
Query: 2266 PLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRM 2325
PLP TVGDFW+++WEQ+S + M+T +E ++KC+ YWP L LR+ LV
Sbjct: 895 PLPQTVGDFWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWP--LDSQPCTHGHLRVTLVGE 952
Query: 2326 QQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHR 2381
+ ++ + VR + L ++ ++ + ++ AWPDH PS PD LL F +R
Sbjct: 953 EVMENWTVRELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTME 1012
Query: 2382 SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFC 2441
GP I HCSAG+GR+GTLI +DV+L + + VR MR R MVQTE QY+F
Sbjct: 1013 GGPPIVHCSAGVGRTGTLIALDVLLRQLQSEGLLGPFSFVRKMRESRPLMVQTEAQYVFL 1072
Query: 2442 YQVILYVLTRLQAEEEQKQQP 2462
+Q IL L + +K+ P
Sbjct: 1073 HQCILRFLQQSAQAPAEKEVP 1093
>gi|223941891 protein tyrosine phosphatase, non-receptor type 3
isoform 6 [Homo sapiens]
Length = 581
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2153 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2212
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 273 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 332
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2270
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 333 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 392
Query: 2271 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2330
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 393 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 450
Query: 2331 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2389
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 451 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 510
Query: 2390 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 511 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 569
Score = 39.7 bits (91), Expect = 0.037
Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)
Query: 1606 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1659
E++ S M ++ K+ +SP R S D+L +T ++ + S
Sbjct: 30 EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 88
Query: 1660 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1719
Q + VSQ +S H+ S+ + Y QK S+ S P APG
Sbjct: 89 APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 136
Query: 1720 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1779
+ +D +H +++ E+ + D ++ + + + LI + E G
Sbjct: 137 --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 188
Query: 1780 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1836
GF + G + V I + +D +L GD+++ +N D++ TH V ++
Sbjct: 189 FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 248
Query: 1837 AA----SKTVRLVIGR 1848
A+ S+ + LVI R
Sbjct: 249 ASRESHSRELALVIRR 264
>gi|223941888 protein tyrosine phosphatase, non-receptor type 3
isoform 5 [Homo sapiens]
Length = 626
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2153 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2212
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 318 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 377
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2270
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 378 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 437
Query: 2271 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2330
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 438 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 495
Query: 2331 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2389
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 496 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 555
Query: 2390 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 556 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 614
Score = 38.9 bits (89), Expect = 0.063
Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)
Query: 1587 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1646
+PA S + S +S N S + + + + P R S +D+ + E +T
Sbjct: 64 NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 120
Query: 1647 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1706
++ + S Q + VSQ +S H+ S+ + Y QK S+
Sbjct: 121 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 169
Query: 1707 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1766
S P APG + +D +H +++ E+ + D ++ + + +
Sbjct: 170 SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 222
Query: 1767 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1823
LI + E G GF + G + V I + +D +L GD+++ +N D+
Sbjct: 223 --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 280
Query: 1824 TNMTHTDAVNLLRAA----SKTVRLVIGR 1848
+ TH V ++A+ S+ + LVI R
Sbjct: 281 SEHTHDQVVMFIKASRESHSRELALVIRR 309
>gi|223941885 protein tyrosine phosphatase, non-receptor type 3
isoform 4 [Homo sapiens]
Length = 737
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2153 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2212
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 429 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 488
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2270
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 489 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 548
Query: 2271 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2330
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 549 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 606
Query: 2331 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2389
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 607 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 666
Query: 2390 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 667 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 725
Score = 75.9 bits (185), Expect = 5e-13
Identities = 50/187 (26%), Positives = 85/187 (45%), Gaps = 17/187 (9%)
Query: 686 DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745
DI E R+ C ++++LAS A+Q+ +GDY +H Y H++P + + L
Sbjct: 2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
Query: 746 ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805
++ LH + G + E E ++ + + L YGV H +++G+ S GV V+
Sbjct: 56 KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
Query: 806 EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860
+ +PW KISF +KK + Q ++ +H F N + C+ L
Sbjct: 114 RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
Query: 861 CSYQHKF 867
C H F
Sbjct: 170 CVEHHTF 176
Score = 39.7 bits (91), Expect = 0.037
Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)
Query: 1606 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1659
E++ S M ++ K+ +SP R S D+L +T ++ + S
Sbjct: 186 EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 244
Query: 1660 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1719
Q + VSQ +S H+ S+ + Y QK S+ S P APG
Sbjct: 245 APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 292
Query: 1720 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1779
+ +D +H +++ E+ + D ++ + + + LI + E G
Sbjct: 293 --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 344
Query: 1780 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1836
GF + G + V I + +D +L GD+++ +N D++ TH V ++
Sbjct: 345 FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 404
Query: 1837 AA----SKTVRLVIGR 1848
A+ S+ + LVI R
Sbjct: 405 ASRESHSRELALVIRR 420
>gi|223941882 protein tyrosine phosphatase, non-receptor type 3
isoform 3 [Homo sapiens]
Length = 782
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2153 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2212
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 474 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 533
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2270
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 534 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 593
Query: 2271 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2330
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 594 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 651
Query: 2331 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2389
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 652 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 711
Query: 2390 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 712 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 770
Score = 79.3 bits (194), Expect = 4e-14
Identities = 98/484 (20%), Positives = 195/484 (40%), Gaps = 51/484 (10%)
Query: 686 DILEERMHCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKE 745
DI E R+ C ++++LAS A+Q+ +GDY +H Y H++P + + L
Sbjct: 2 DICEGRLTCPLNSAVVLASYAVQSHFGDYNSSIHHPGYLSDSHFIPDQNEDFL------T 55
Query: 746 ELPKLHNTYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVF 805
++ LH + G + E E ++ + + L YGV H +++G+ S GV V+
Sbjct: 56 KVESLHEQHSGLKQSEAESCYINIARTLDFYGVELH--SGRDLHNLDLMIGIASAGVAVY 113
Query: 806 EVHNGVRTLVLRFPWRETKKISFSKKKITL---QNTSDGIKH--GFQTDNSKICQYLLHL 860
+ +PW KISF +KK + Q ++ +H F N + C+ L
Sbjct: 114 RKY----ICTSFYPWVNILKISFKRKKFFIHQRQKQAESREHIVAFNMLNYRSCKNLWKS 169
Query: 861 CSYQHKFQLQMRARQSNQDAQDI--------ERASFRSLNLQ-AESVRGFNMGRAISTGS 911
C H F +A++ +++ R + +S+N Q + V G + S
Sbjct: 170 CVEHHTF---FQAKKLLPQEKNVLSQYWTMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRS 226
Query: 912 LASSTLNKLAVRPLSVQAEILKRLSCSELSLYQPLQNSSKEKNDKASWEEKPREMSKSYH 971
L+ L ++ S R + +P +S+ ++ ++ + ++ +Y
Sbjct: 227 LSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTY- 285
Query: 972 DLSQASLYPHRKNVIVNMEPPPQTVAELVGKPSHQ-MSRSDAESLAGVTKLNNSKSVASL 1030
+ SL P + V+ P + P+ +++ + S++ + S S +
Sbjct: 286 ---KGSLAPQDSDSEVSQNRSPHQESLSENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGV 342
Query: 1031 NRSPERRKHE-SDSSSIEDPGQAYVLDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQI 1089
++ H + S ED Q Y + + + L+ + D GF +
Sbjct: 343 DQQLLDDFHRVTKGGSTEDASQYYC--------DKNDNGDSYLVLIRITPDEDGKFGFNL 394
Query: 1090 IGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVNSVSLEGVSHHAAIEILQ 1146
GG + + +S + P PAD C L GD+++ +N + +H + ++
Sbjct: 395 KGGVDQ---KMPLVVSRINPESPADT--CIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 449
Query: 1147 NAPE 1150
+ E
Sbjct: 450 ASRE 453
Score = 38.9 bits (89), Expect = 0.063
Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)
Query: 1587 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1646
+PA S + S +S N S + + + + P R S +D+ + E +T
Sbjct: 220 NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 276
Query: 1647 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1706
++ + S Q + VSQ +S H+ S+ + Y QK S+
Sbjct: 277 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 325
Query: 1707 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1766
S P APG + +D +H +++ E+ + D ++ + + +
Sbjct: 326 SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 378
Query: 1767 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1823
LI + E G GF + G + V I + +D +L GD+++ +N D+
Sbjct: 379 --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 436
Query: 1824 TNMTHTDAVNLLRAA----SKTVRLVIGR 1848
+ TH V ++A+ S+ + LVI R
Sbjct: 437 SEHTHDQVVMFIKASRESHSRELALVIRR 465
>gi|223941879 protein tyrosine phosphatase, non-receptor type 3
isoform 2 [Homo sapiens]
Length = 868
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2153 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2212
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 560 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 619
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2270
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 620 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 679
Query: 2271 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2330
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 680 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 737
Query: 2331 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2389
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 738 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 797
Query: 2390 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 798 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 856
Score = 112 bits (281), Expect = 3e-24
Identities = 79/279 (28%), Positives = 126/279 (45%), Gaps = 33/279 (11%)
Query: 597 VFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPK---KKTKATVN 653
+ DMV H+G+ E F L D+ V W E K K+ K
Sbjct: 54 LLDMVHNHLGVTEKEYFGLQHDDDS-------------VDSPRWLEASKAIRKQLKGGFP 100
Query: 654 FTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGD 713
TL FR++FF+ D + +Q T H Y+LQL+ DI E R+ C ++++LAS A+Q+ +GD
Sbjct: 101 CTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGD 160
Query: 714 YQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRL 773
Y +H Y H++P + + L ++ LH + G + E E ++ + + L
Sbjct: 161 YNSSIHHPGYLSDSHFIPDQNEDFL------TKVESLHEQHSGLKQSEAESCYINIARTL 214
Query: 774 TEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKI 833
YGV H +++G+ S GV V+ + +PW KISF +KK
Sbjct: 215 DFYGVELH--SGRDLHNLDLMIGIASAGVAVYRKY----ICTSFYPWVNILKISFKRKKF 268
Query: 834 TL---QNTSDGIKH--GFQTDNSKICQYLLHLCSYQHKF 867
+ Q ++ +H F N + C+ L C H F
Sbjct: 269 FIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTF 307
Score = 39.7 bits (91), Expect = 0.037
Identities = 56/256 (21%), Positives = 103/256 (40%), Gaps = 34/256 (13%)
Query: 1606 EQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDL------VTAPANISNSTWSSA 1659
E++ S M ++ K+ +SP R S D+L +T ++ + S
Sbjct: 317 EKNVLSQYWTMGSRNTKK-RSPRLRHEIRKPRHSSADNLANEMTYITETEDVFYTYKGSL 375
Query: 1660 LHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSY 1719
Q + VSQ +S H+ S+ + Y QK S+ S P APG
Sbjct: 376 APQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSSSVSPSSNAPGSC- 423
Query: 1720 QPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS 1779
+ +D +H +++ E+ + D ++ + + + LI + E G
Sbjct: 424 --SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV----LIRITPDEDGK 475
Query: 1780 LGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1836
GF + G + V I + +D +L GD+++ +N D++ TH V ++
Sbjct: 476 FGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDISEHTHDQVVMFIK 535
Query: 1837 AA----SKTVRLVIGR 1848
A+ S+ + LVI R
Sbjct: 536 ASRESHSRELALVIRR 551
>gi|223941876 protein tyrosine phosphatase, non-receptor type 3
isoform 1 [Homo sapiens]
Length = 913
Score = 190 bits (482), Expect = 2e-47
Identities = 110/299 (36%), Positives = 156/299 (52%), Gaps = 5/299 (1%)
Query: 2153 FLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENLQELKPLDQCLI 2212
F + DEL L + P G L+ + L+ L+ G + E L KP
Sbjct: 605 FKSEDELNQLFPEAIFPMCPEGGDTLEGSMAQLKKGLESGTVLIQFEQLYRKKPGLAITF 664
Query: 2213 GQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV--YIACQGPLPTT 2270
+ +N KNRYK++LPYD TRV L YINAS++ + + V YIA QGPLP T
Sbjct: 665 AKLPQNLDKNRYKDVLPYDTTRVLLQGNEDYINASYVNMEIPAANLVNKYIATQGPLPHT 724
Query: 2271 VGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKG 2330
FWQ++W+QK ++I M+T E + KC +YWP+ M +
Sbjct: 725 CAQFWQVVWDQKLSLIVMLTTLTERGRTKCHQYWPD--PPDVMNHGGFHIQCQSEDCTIA 782
Query: 2331 FVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-RSGPIITHC 2389
+V R M + + QT E ++HL + AWPDH P D L F++Y+R + S P++ HC
Sbjct: 783 YVSREMLVTNTQTGEEHTVTHLQYVAWPDHGVPDDSSDFLEFVNYVRSLRVDSEPVLVHC 842
Query: 2390 SAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
SAGIGR+G L+ ++ + L ++L D+VR MR QR MVQT QY F + IL V
Sbjct: 843 SAGIGRTGVLVTMETAMCLTERNLPIYPLDIVRKMRDQRAMMVQTSSQYKFVCEAILRV 901
Score = 116 bits (290), Expect = 3e-25
Identities = 127/576 (22%), Positives = 236/576 (40%), Gaps = 67/576 (11%)
Query: 597 VFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAPEGWKEEPK---KKTKATVN 653
+ DMV H+G+ E F L D+ V W E K K+ K
Sbjct: 54 LLDMVHNHLGVTEKEYFGLQHDDDS-------------VDSPRWLEASKAIRKQLKGGFP 100
Query: 654 FTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCDDETSLLLASLALQAEYGD 713
TL FR++FF+ D + +Q T H Y+LQL+ DI E R+ C ++++LAS A+Q+ +GD
Sbjct: 101 CTLHFRVRFFIPDPNTLQQEQTRHLYFLQLKMDICEGRLTCPLNSAVVLASYAVQSHFGD 160
Query: 714 YQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNTYVGASEKETELEFLKVCQRL 773
Y +H Y H++P + + L ++ LH + G + E E ++ + + L
Sbjct: 161 YNSSIHHPGYLSDSHFIPDQNEDFL------TKVESLHEQHSGLKQSEAESCYINIARTL 214
Query: 774 TEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVRTLVLRFPWRETKKISFSKKKI 833
YGV H +++G+ S GV V+ + +PW KISF +KK
Sbjct: 215 DFYGVELH--SGRDLHNLDLMIGIASAGVAVYRKY----ICTSFYPWVNILKISFKRKKF 268
Query: 834 TL---QNTSDGIKH--GFQTDNSKICQYLLHLCSYQHKFQLQMRARQSNQDAQDI----- 883
+ Q ++ +H F N + C+ L C H F +A++ +++
Sbjct: 269 FIHQRQKQAESREHIVAFNMLNYRSCKNLWKSCVEHHTF---FQAKKLLPQEKNVLSQYW 325
Query: 884 ---ERASFRSLNLQ-AESVRGFNMGRAISTGSLASSTLNKLAVRPLSVQAEILKRLSCSE 939
R + +S+N Q + V G + SL+ L ++ S R
Sbjct: 326 TMGSRNTKKSVNNQYCKKVIGGMVWNPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLR 385
Query: 940 LSLYQPLQNSSKEKNDKASWEEKPREMSKSYHDLSQASLYPHRKNVIVNMEPPPQTVAEL 999
+ +P +S+ ++ ++ + ++ +Y + SL P + V+ P +
Sbjct: 386 HEIRKPRHSSADNLANEMTYITETEDVFYTY----KGSLAPQDSDSEVSQNRSPHQESLS 441
Query: 1000 VGKPSHQ-MSRSDAESLAGVTKLNNSKSVASLNRSPERRKHE-SDSSSIEDPGQAYVLDV 1057
P+ +++ + S++ + S S +++ H + S ED Q Y
Sbjct: 442 ENNPAQSYLTQKSSSSVSPSSNAPGSCSPDGVDQQLLDDFHRVTKGGSTEDASQYYC--- 498
Query: 1058 LHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDG 1117
+ + + L+ + D GF + GG + + +S + P PAD
Sbjct: 499 -----DKNDNGDSYLVLIRITPDEDGKFGFNLKGGVDQ---KMPLVVSRINPESPADT-- 548
Query: 1118 C---LKPGDRLISVNSVSLEGVSHHAAIEILQNAPE 1150
C L GD+++ +N + +H + ++ + E
Sbjct: 549 CIPKLNEGDQIVLINGRDISEHTHDQVVMFIKASRE 584
Score = 38.9 bits (89), Expect = 0.063
Identities = 58/269 (21%), Positives = 108/269 (40%), Gaps = 30/269 (11%)
Query: 1587 SPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT 1646
+PA S + S +S N S + + + + P R S +D+ + E +T
Sbjct: 351 NPAMRRSLSVEHLETKSLPSRSPPITPNWRSPRLRHEIRKP--RHSSADNLAN-EMTYIT 407
Query: 1647 APANISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNP 1706
++ + S Q + VSQ +S H+ S+ + Y QK S+
Sbjct: 408 ETEDVFYTYKGSLAPQDSDSEVSQNRSPHQESLSENNP--AQSYLTQK---------SSS 456
Query: 1707 SPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEV 1766
S P APG + +D +H +++ E+ + D ++ + + +
Sbjct: 457 SVSPSSNAPGSC---SPDGVDQQLLDDFH--RVTKGGSTEDASQYYCDKNDNGDSYLV-- 509
Query: 1767 ELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSDG---RLKPGDRLIKVNDTDV 1823
LI + E G GF + G + V I + +D +L GD+++ +N D+
Sbjct: 510 --LIRITPDEDGKFGFNLKGGVDQKMPLVVSRINPESPADTCIPKLNEGDQIVLINGRDI 567
Query: 1824 TNMTHTDAVNLLRAA----SKTVRLVIGR 1848
+ TH V ++A+ S+ + LVI R
Sbjct: 568 SEHTHDQVVMFIKASRESHSRELALVIRR 596
>gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [Homo
sapiens]
Length = 593
Score = 189 bits (480), Expect = 3e-47
Identities = 125/330 (37%), Positives = 175/330 (53%), Gaps = 31/330 (9%)
Query: 2161 VLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSK-----ELENLQ--ELKPLDQCLIG 2213
VL + + L + + A ++S +R L L + K E E LQ E K L G
Sbjct: 209 VLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEG 268
Query: 2214 QTKENRRKNRYKNILPYDATRVPLGDE------GGYINASFI------KIPVGKEEFVYI 2261
Q +EN+ KNRYKNILP+D TRV L D YINA+ I K K + YI
Sbjct: 269 QRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYI 328
Query: 2262 ACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLA 2321
A QG L TV DFW+M++++ S VI M T+EVE K KC +YWP+ +R+
Sbjct: 329 ATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEY--GVMRVR 386
Query: 2322 LVRMQQLKGFVVRAMTLEDI-QTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRH-- 2378
V+ + +R + L + Q R + +F WPDH PS P +L F+ + H
Sbjct: 387 NVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQ 446
Query: 2379 --IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFDISDLVRCMRLQRHGMVQ 2433
I +GP++ HCSAGIGR+GT I ID+++ +I + D D D+ ++ +R QR GMVQ
Sbjct: 447 ESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQ 506
Query: 2434 TEDQYIFCYQVILYVLTRLQ--AEEEQKQQ 2461
TE QY F Y + + + LQ EEEQK +
Sbjct: 507 TEAQYRFIYMAVQHYIETLQRRIEEEQKSK 536
>gi|4506295 protein tyrosine phosphatase, non-receptor type 4 [Homo
sapiens]
Length = 926
Score = 186 bits (473), Expect = 2e-46
Identities = 104/275 (37%), Positives = 156/275 (56%), Gaps = 9/275 (3%)
Query: 2179 KSVIRVLRGLLDQGIPSKELENLQELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLG 2238
+S+I++ GL+ G + + L KP + +N KNRY++I PYDATRV L
Sbjct: 641 ESMIQLAEGLIT-GTVLTQFDQLYRKKPGMTMSCAKLPQNISKNRYRDISPYDATRVILK 699
Query: 2239 DEGGYINASFIKIPVGKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGE 2296
YINA++I + + + YIACQGPLP T DFWQM WEQ S+++ M+T +VE
Sbjct: 700 GNEDYINANYINMEIPSSSIINQYIACQGPLPHTCTDFWQMTWEQGSSMVVMLTTQVERG 759
Query: 2297 KIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTA 2356
++KC +YWP G ++ ++ + ++ R MTL + + E R ++ + + A
Sbjct: 760 RVKCHQYWPEPTGSSSY--GCYQVTCHSEEGNTAYIFRKMTLFNQEKNESRPLTQIQYIA 817
Query: 2357 WPDHDTPSQPDDLLTFISYMRHIHRSG---PIITHCSAGIGRSGTLICIDVVLGLISQDL 2413
WPDH P D L F+ ++R+ R+G P++ HCSAGIGR+G LI ++ + LI +
Sbjct: 818 WPDHGVPDDSSDFLDFVCHVRN-KRAGKEEPVVVHCSAGIGRTGVLITMETAMCLIECNQ 876
Query: 2414 DFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
D+VR MR QR M+QT QY F + IL V
Sbjct: 877 PVYPLDIVRTMRDQRAMMIQTPSQYRFVCEAILKV 911
Score = 149 bits (377), Expect = 3e-35
Identities = 172/674 (25%), Positives = 287/674 (42%), Gaps = 94/674 (13%)
Query: 575 NIMLLNGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALATLKDN--EYFFVDPDLKL 632
NI+LL+ + + + D+V H+ L E F L D+ ++DP+ +
Sbjct: 32 NILLLDNTVQAFKVNKHDQGQVLLDVVFKHLDLTEQDYFGLQLADDSTDNPRWLDPNKPI 91
Query: 633 TKVAPEGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERM 692
+K+ K ++L FR+KFF+ D + +Q T +QY+LQ+++DIL R+
Sbjct: 92 ------------RKQLKRGSPYSLNFRVKFFVSDPNKLQEEYTRYQYFLQIKQDILTGRL 139
Query: 693 HCDDETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHN 752
C T+ LLAS A+Q+E GDY + Y ++P + + ++E+ KLH
Sbjct: 140 PCPSNTAALLASFAVQSELGDYDQSENLSGYLSDYSFIPNQPQD------FEKEIAKLHQ 193
Query: 753 TYVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGVR 812
++G S E E +L + L YGV FH + +S I++GV S G+L+++ N VR
Sbjct: 194 QHIGLSPAEAEFNYLNTARTLELYGVEFH--YARDQSNNEIMIGVMSGGILIYK--NRVR 249
Query: 813 TLVLRFPWRETKKISFSKKKITLQ-----NTSDGIKHGFQTDNSKICQYLLHLCSYQHKF 867
+ FPW + KISF K+ +Q + S GF N + C+ L C H F
Sbjct: 250 --MNTFPWLKIVKISFKCKQFFIQLRKELHESRETLLGFNMVNYRACKNLWKACVEHHTF 307
Query: 868 QLQMR--ARQSNQDAQDIERAS-FRSL-NLQAESVRGFNMGRAISTGSLASSTLNKLAVR 923
R Q N A S FR + +SV+ + +A A S LA +
Sbjct: 308 FRLDRPLPPQKNFFAHYFTLGSKFRYCGRTEVQSVQ-YGKEKANKDRVFARSPSKPLARK 366
Query: 924 PLSVQAEILKRLSCSELSLYQ---PLQNSSKEKNDKAS--WEEKPREMSKSYHDLSQASL 978
+ E++ R S S+ L P ++ N + S +E R S L +
Sbjct: 367 --LMDWEVVSRNSISDDRLETQSLPSRSPPGTPNHRNSTFTQEGTRLRPSSVGHLVDHMV 424
Query: 979 YPHRKNVIVNMEPPPQTVAE---LVGKPSHQMSRSDAESLAGVTKLNNSKSVASLNRSPE 1035
+ V VN P T A L PS Q + D + A K + S ++ S
Sbjct: 425 HTSPSEVFVNQRSPSSTQANSIVLESSPS-QETPGDGKPPALPPKQSKKNSWNQIHYSHS 483
Query: 1036 RRKHESDSSSIEDPGQAYVLDVLHKRWSIVSSPER----------EITLVNLKKDAKYGL 1085
++ ES +++ + I SSPE+ + L+ +K D
Sbjct: 484 QQDLESH---------------INETFDIPSSPEKPTPNGGIPHDNLVLIRMKPDENGRF 528
Query: 1086 GFQIIGGEKMGRLDLGIFISSVAPGGPADLDGC---LKPGDRLISVNSVSLEGVSHHAAI 1142
GF + GG + + +S VAPG PADL C L GD+++ +N + +H +
Sbjct: 529 GFNVKGGYDQ---KMPVIVSRVAPGTPADL--CVPRLNEGDQVVLINGRDIAEHTHDQVV 583
Query: 1143 EILQNAPE----DVTLVISQPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSA-IDSSSK 1197
++ + E ++ L++ P+ + E Y+ + A +DS +
Sbjct: 584 LFIKASCERHSGELMLLVR---------PNAVYDVVEEKLENEPDFQYIPEKAPLDSVHQ 634
Query: 1198 DHHWSRGTLRHISE 1211
D H R ++ ++E
Sbjct: 635 DDHSLRESMIQLAE 648
Score = 39.7 bits (91), Expect = 0.037
Identities = 33/146 (22%), Positives = 57/146 (39%), Gaps = 11/146 (7%)
Query: 1696 PNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIHHISEPTRQENWTPLKNDL 1755
P++ D P LPP + S+ S S ++ + P+ E TP
Sbjct: 452 PSQETPGDGKPPALPPKQSKKNSWNQIHYSHSQQDLESHINETFDIPSSPEKPTPNGGIP 511
Query: 1756 ENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYVHDVIQDPAKSD---GRLKPG 1812
++L +LI + E G GF V G + + + +D RL G
Sbjct: 512 HDNL--------VLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEG 563
Query: 1813 DRLIKVNDTDVTNMTHTDAVNLLRAA 1838
D+++ +N D+ TH V ++A+
Sbjct: 564 DQVVLINGRDIAEHTHDQVVLFIKAS 589
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 183 bits (464), Expect = 2e-45
Identities = 94/240 (39%), Positives = 140/240 (58%), Gaps = 12/240 (5%)
Query: 2218 NRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
N+ KNRY N++ YD +RV L G YINA++I +++ YIA QGPLP T+G
Sbjct: 1375 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYID--GYRKQNAYIATQGPLPETMG 1432
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFW+M+WEQ++ + MMT+ E ++KC +YWP + T +++ L+ +L +
Sbjct: 1433 DFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP---ARGTETCGLIQVTLLDTVELATYT 1489
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SGPIITHCS 2390
VR L + E R + F AWPDH P P +L F+ ++ + +GP++ HCS
Sbjct: 1490 VRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCS 1549
Query: 2391 AGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT 2450
AG+GR+G I ID +L + + DI V CMR QR+ MVQTEDQY+F ++ +L T
Sbjct: 1550 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT 1609
Score = 150 bits (379), Expect = 1e-35
Identities = 90/241 (37%), Positives = 127/241 (52%), Gaps = 14/241 (5%)
Query: 2218 NRRKNRYKNILPYDATRVPL----GDEGG-YINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
N+ KNR NI+PY+ TRV L G EG YINASF+ +++ YIA QGPL +
Sbjct: 1664 NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD--GYRQQKAYIATQGPLAESTE 1721
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFW+M+WE ST+I M+T+ E + KC +YWP +A M Q ++
Sbjct: 1722 DFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ---YI 1778
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHRSGPIITH 2388
+R + D + + R I FT WP+ P + + FI + + GPI H
Sbjct: 1779 LREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVH 1838
Query: 2389 CSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
CSAG+GR+G I + +VL + + D+ V+ +R QR MVQTEDQY CY+ L
Sbjct: 1839 CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY 1898
Query: 2449 L 2449
L
Sbjct: 1899 L 1899
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 183 bits (464), Expect = 2e-45
Identities = 94/240 (39%), Positives = 140/240 (58%), Gaps = 12/240 (5%)
Query: 2218 NRRKNRYKNILPYDATRVPLGDEGG-----YINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
N+ KNRY N++ YD +RV L G YINA++I +++ YIA QGPLP T+G
Sbjct: 1366 NKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYID--GYRKQNAYIATQGPLPETMG 1423
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFW+M+WEQ++ + MMT+ E ++KC +YWP + T +++ L+ +L +
Sbjct: 1424 DFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWP---ARGTETCGLIQVTLLDTVELATYT 1480
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIHR--SGPIITHCS 2390
VR L + E R + F AWPDH P P +L F+ ++ + +GP++ HCS
Sbjct: 1481 VRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCS 1540
Query: 2391 AGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVLT 2450
AG+GR+G I ID +L + + DI V CMR QR+ MVQTEDQY+F ++ +L T
Sbjct: 1541 AGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAT 1600
Score = 150 bits (379), Expect = 1e-35
Identities = 90/241 (37%), Positives = 127/241 (52%), Gaps = 14/241 (5%)
Query: 2218 NRRKNRYKNILPYDATRVPL----GDEGG-YINASFIKIPVGKEEFVYIACQGPLPTTVG 2272
N+ KNR NI+PY+ TRV L G EG YINASF+ +++ YIA QGPL +
Sbjct: 1655 NKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLD--GYRQQKAYIATQGPLAESTE 1712
Query: 2273 DFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLALVRMQQLKGFV 2332
DFW+M+WE ST+I M+T+ E + KC +YWP +A M Q ++
Sbjct: 1713 DFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQ---YI 1769
Query: 2333 VRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMR----HIHRSGPIITH 2388
+R + D + + R I FT WP+ P + + FI + + GPI H
Sbjct: 1770 LREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVH 1829
Query: 2389 CSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIFCYQVILYV 2448
CSAG+GR+G I + +VL + + D+ V+ +R QR MVQTEDQY CY+ L
Sbjct: 1830 CSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEY 1889
Query: 2449 L 2449
L
Sbjct: 1890 L 1890
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 182 bits (462), Expect = 4e-45
Identities = 100/246 (40%), Positives = 148/246 (60%), Gaps = 15/246 (6%)
Query: 2212 IGQTKENRRKNRYKNILPYDATRV---PLGDE--GGYINASFIKIPVGKEEFV----YIA 2262
+ + +NR KNRY NI+ YD +RV P+ D+ YINA++I I + ++ + YIA
Sbjct: 905 VAKKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIA 964
Query: 2263 CQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNRLRLAL 2322
QGP+ TV DFW+MIW+++S I M+T VE ++KC +YWP+ T V ++
Sbjct: 965 TQGPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWPD----DTEVYGDFKVTC 1020
Query: 2323 VRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISYMRHIH-- 2380
V M+ L +VVR TLE E+R + +FT WPDH P LL+FI ++ +
Sbjct: 1021 VEMEPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPP 1080
Query: 2381 RSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQTEDQYIF 2440
+GPI+ HCSAG GR+G I ID++L + ++ DI + V+ +R +R MVQTE+QYIF
Sbjct: 1081 SAGPIVVHCSAGAGRTGCYIVIDIMLDMAEREGVVDIYNCVKALRSRRINMVQTEEQYIF 1140
Query: 2441 CYQVIL 2446
+ IL
Sbjct: 1141 IHDAIL 1146
Score = 84.7 bits (208), Expect = 1e-15
Identities = 71/274 (25%), Positives = 114/274 (41%), Gaps = 34/274 (12%)
Query: 2197 ELENLQELKP---LDQCLIGQTKENRRKNRYKNILPYDATRVPL----GDEGGYINASFI 2249
E + L + P + C I N KNR+ ++LP D L G+ YINA+ +
Sbjct: 1183 EFQTLNSVTPRLQAEDCSIACLPRNHDKNRFMDMLPPDRCLPFLITIDGESSNYINAALM 1242
Query: 2250 KIPVGKEEFVYIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILG 2309
++ +I Q PLP TV DFW+++++ T I M+ EV+ + C +YWP
Sbjct: 1243 DSY--RQPAAFIVTQYPLPNTVKDFWRLVYDYGCTSIVML-NEVDLSQ-GCPQYWPE--- 1295
Query: 2310 KTTMVSNRLRLALVRMQQLK--------GFVVRAMTLEDIQTREVRHISHLNFTAWPDH- 2360
LR ++++ + + R L Q + + + W H
Sbjct: 1296 -----EGMLRYGPIQVECMSCSMDCDVINRIFRICNLTRPQEGYLM-VQQFQYLGWASHR 1349
Query: 2361 DTPSQPDDLLTFISYMRHIHR-----SGPIITHCSAGIGRSGTLICIDVVLGLISQDLDF 2415
+ P L I + G I HC G GRSG I +V+ ++ +
Sbjct: 1350 EVPGSKRSFLKLILQVEKWQEECEEGEGRTIIHCLNGGGRSGMFCAIGIVVEMVKRQNVV 1409
Query: 2416 DISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL 2449
D+ V+ +R + MV+ +QY FCY V L L
Sbjct: 1410 DVFHAVKTLRNSKPNMVEAPEQYRFCYDVALEYL 1443
>gi|18104993 protein tyrosine phosphatase, non-receptor type 6 isoform
3 [Homo sapiens]
Length = 624
Score = 182 bits (462), Expect = 4e-45
Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)
Query: 2196 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2247
+E E+LQ E+K L Q L GQ EN+ KNRYKNILP+D +RV L YINA+
Sbjct: 246 EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 305
Query: 2248 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2304
+IK + G +E YIA QG L TV DFWQM W++ S VI M T+EVE + KC YW
Sbjct: 306 YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 365
Query: 2305 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2363
P + + + +R + + + + +R I H + +WPDH P
Sbjct: 366 PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 423
Query: 2364 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2416
S+P +L+F+ + + +GPII HCSAGIGR+GT+I ID+++ IS D D D
Sbjct: 424 SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 483
Query: 2417 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2463
I ++ +R QR GMVQTE QY F Y I + T+ + E Q Q+ Q
Sbjct: 484 IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 532
>gi|18104989 protein tyrosine phosphatase, non-receptor type 6 isoform
1 [Homo sapiens]
Length = 595
Score = 182 bits (462), Expect = 4e-45
Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)
Query: 2196 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2247
+E E+LQ E+K L Q L GQ EN+ KNRYKNILP+D +RV L YINA+
Sbjct: 246 EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 305
Query: 2248 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2304
+IK + G +E YIA QG L TV DFWQM W++ S VI M T+EVE + KC YW
Sbjct: 306 YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 365
Query: 2305 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2363
P + + + +R + + + + +R I H + +WPDH P
Sbjct: 366 PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 423
Query: 2364 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2416
S+P +L+F+ + + +GPII HCSAGIGR+GT+I ID+++ IS D D D
Sbjct: 424 SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 483
Query: 2417 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2463
I ++ +R QR GMVQTE QY F Y I + T+ + E Q Q+ Q
Sbjct: 484 IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 532
>gi|18104991 protein tyrosine phosphatase, non-receptor type 6 isoform
2 [Homo sapiens]
Length = 597
Score = 182 bits (462), Expect = 4e-45
Identities = 116/289 (40%), Positives = 160/289 (55%), Gaps = 23/289 (7%)
Query: 2196 KELENLQ--ELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGG------YINAS 2247
+E E+LQ E+K L Q L GQ EN+ KNRYKNILP+D +RV L YINA+
Sbjct: 248 EEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINAN 307
Query: 2248 FIKIPV-GKEEFV--YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYW 2304
+IK + G +E YIA QG L TV DFWQM W++ S VI M T+EVE + KC YW
Sbjct: 308 YIKNQLLGPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYW 367
Query: 2305 PNILGKTTMVSNRLRLALVRMQQLKGFVVRAMTLEDIQTRE-VRHISHLNFTAWPDHDTP 2363
P + + + +R + + + + +R I H + +WPDH P
Sbjct: 368 PEV--GMQRAYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVP 425
Query: 2364 SQPDDLLTFISYMRH----IHRSGPIITHCSAGIGRSGTLICIDVVLGLISQ---DLDFD 2416
S+P +L+F+ + + +GPII HCSAGIGR+GT+I ID+++ IS D D D
Sbjct: 426 SEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDID 485
Query: 2417 ISDLVRCMRLQRHGMVQTEDQYIFCYQVILYVL--TRLQAEEEQKQQPQ 2463
I ++ +R QR GMVQTE QY F Y I + T+ + E Q Q+ Q
Sbjct: 486 IQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQKGQ 534
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,380,743
Number of Sequences: 37866
Number of extensions: 4584468
Number of successful extensions: 15684
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 190
Number of HSP's that attempted gapping in prelim test: 12918
Number of HSP's gapped (non-prelim): 2118
length of query: 2466
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2347
effective length of database: 13,741,464
effective search space: 32251216008
effective search space used: 32251216008
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.