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Search of human proteins with 5453808
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453808 neurotrophin 5 preproprotein [Homo sapiens]
(210 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453808 neurotrophin 5 preproprotein [Homo sapiens] 431 e-121
gi|156630995 neurotrophin 3 isoform 1 preproprotein [Homo sapiens] 167 6e-42
gi|4505469 neurotrophin 3 isoform 2 preproprotein [Homo sapiens] 167 6e-42
gi|219842314 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842312 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842309 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842306 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842303 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842300 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842298 brain-derived neurotrophic factor isoform e [Homo s... 158 4e-39
gi|219842296 brain-derived neurotrophic factor isoform d preprop... 158 4e-39
gi|219842294 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842292 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842290 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|219842288 brain-derived neurotrophic factor isoform a preprop... 158 4e-39
gi|25306264 brain-derived neurotrophic factor isoform a prepropr... 158 4e-39
gi|25306261 brain-derived neurotrophic factor isoform c prepropr... 158 4e-39
gi|25306267 brain-derived neurotrophic factor isoform a prepropr... 158 4e-39
gi|25306257 brain-derived neurotrophic factor isoform a prepropr... 158 4e-39
gi|25306253 brain-derived neurotrophic factor isoform a prepropr... 158 4e-39
gi|25306235 brain-derived neurotrophic factor isoform b prepropr... 158 4e-39
gi|70995319 nerve growth factor, beta polypeptide precursor [Hom... 129 2e-30
gi|119220598 apolipoprotein B48 receptor [Homo sapiens] 35 0.046
gi|221139926 NHS-like 1 [Homo sapiens] 34 0.079
gi|210032580 SET domain containing 1B [Homo sapiens] 33 0.18
gi|31077092 neurogenin 2 [Homo sapiens] 33 0.23
gi|239754969 PREDICTED: hypothetical protein [Homo sapiens] 32 0.39
gi|239749517 PREDICTED: hypothetical protein [Homo sapiens] 32 0.39
gi|239743656 PREDICTED: hypothetical protein XP_002342923 [Homo ... 32 0.39
gi|122692281 hypothetical protein LOC645369 [Homo sapiens] 32 0.39
>gi|5453808 neurotrophin 5 preproprotein [Homo sapiens]
Length = 210
Score = 431 bits (1109), Expect = e-121
Identities = 210/210 (100%), Positives = 210/210 (100%)
Query: 1 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF 60
MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF
Sbjct: 1 MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLF 60
Query: 61 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV 120
LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV
Sbjct: 61 LLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEV 120
Query: 121 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL 180
LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL
Sbjct: 121 LGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRAL 180
Query: 181 TADAQGRVGWRWIRIDTACVCTLLSRTGRA 210
TADAQGRVGWRWIRIDTACVCTLLSRTGRA
Sbjct: 181 TADAQGRVGWRWIRIDTACVCTLLSRTGRA 210
>gi|156630995 neurotrophin 3 isoform 1 preproprotein [Homo sapiens]
Length = 270
Score = 167 bits (423), Expect = 6e-42
Identities = 91/201 (45%), Positives = 120/201 (59%), Gaps = 22/201 (10%)
Query: 18 PSVPIESQPPPSTLPPFLAPEWDLL-------SPRVVLSRGAPAGPPLLFLLEAGAFRES 70
P P P S P +A + +LL SPRV+LS P PP L+L+E +
Sbjct: 82 PREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLME-----DY 136
Query: 71 AGAP--ANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAG 128
G+P ANR+ R S RGE +VCD+ S WVTD+ +A+D+RG +V VLGE+ G
Sbjct: 137 VGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKT-G 195
Query: 129 GSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRV 188
SP++QYF+ETRCK + G CRG+D +HW S+CK Q+YVRALT++ V
Sbjct: 196 NSPVKQYFYETRCKEARPVKNG-------CRGIDDKHWNSQCKTSQTYVRALTSENNKLV 248
Query: 189 GWRWIRIDTACVCTLLSRTGR 209
GWRWIRIDT+CVC L + GR
Sbjct: 249 GWRWIRIDTSCVCALSRKIGR 269
>gi|4505469 neurotrophin 3 isoform 2 preproprotein [Homo sapiens]
Length = 257
Score = 167 bits (423), Expect = 6e-42
Identities = 91/201 (45%), Positives = 120/201 (59%), Gaps = 22/201 (10%)
Query: 18 PSVPIESQPPPSTLPPFLAPEWDLL-------SPRVVLSRGAPAGPPLLFLLEAGAFRES 70
P P P S P +A + +LL SPRV+LS P PP L+L+E +
Sbjct: 69 PREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLME-----DY 123
Query: 71 AGAP--ANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAG 128
G+P ANR+ R S RGE +VCD+ S WVTD+ +A+D+RG +V VLGE+ G
Sbjct: 124 VGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKT-G 182
Query: 129 GSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRV 188
SP++QYF+ETRCK + G CRG+D +HW S+CK Q+YVRALT++ V
Sbjct: 183 NSPVKQYFYETRCKEARPVKNG-------CRGIDDKHWNSQCKTSQTYVRALTSENNKLV 235
Query: 189 GWRWIRIDTACVCTLLSRTGR 209
GWRWIRIDT+CVC L + GR
Sbjct: 236 GWRWIRIDTSCVCALSRKIGR 256
>gi|219842314 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842312 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842309 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842306 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842303 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842300 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842298 brain-derived neurotrophic factor isoform e [Homo
sapiens]
Length = 329
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 170 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 225
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 226 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 277
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 278 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 329
>gi|219842296 brain-derived neurotrophic factor isoform d
preproprotein [Homo sapiens]
Length = 276
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 117 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 172
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 173 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 224
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 225 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 276
>gi|219842294 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842292 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842290 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|219842288 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|25306264 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|25306261 brain-derived neurotrophic factor isoform c
preproprotein [Homo sapiens]
Length = 262
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 103 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 158
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 159 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 210
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 211 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 262
>gi|25306267 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|25306257 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|25306253 brain-derived neurotrophic factor isoform a
preproprotein [Homo sapiens]
Length = 247
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 88 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 143
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 144 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 195
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 196 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247
>gi|25306235 brain-derived neurotrophic factor isoform b
preproprotein [Homo sapiens]
Length = 255
Score = 158 bits (399), Expect = 4e-39
Identities = 89/172 (51%), Positives = 115/172 (66%), Gaps = 14/172 (8%)
Query: 40 DLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDA 99
DL + RV+LS P PPLLFLLE ++ A AN S R + PA RRGEL+VCD+
Sbjct: 96 DLYTSRVMLSSQVPLEPPLLFLLEE--YKNYLDA-ANMSMRVRRHSDPA-RRGELSVCDS 151
Query: 100 VSGWVT--DRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGG 157
+S WVT D++TAVD+ G V VL +VP + G L+QYF+ET+C G G
Sbjct: 152 ISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQ-LKQYFYETKCNP-------MGYTKEG 203
Query: 158 CRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGR 209
CRG+D+RHW S+C+ QSYVRALT D++ R+GWR+IRIDT+CVCTL + GR
Sbjct: 204 CRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 255
>gi|70995319 nerve growth factor, beta polypeptide precursor [Homo
sapiens]
Length = 241
Score = 129 bits (324), Expect = 2e-30
Identities = 77/181 (42%), Positives = 102/181 (56%), Gaps = 13/181 (7%)
Query: 30 TLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGV-SETAPA 88
T+ P L + L SPRV+ S P L+ F AP NR+ R S + P
Sbjct: 71 TVDPRLFKKRRLRSPRVLFSTQPPREAADTQDLD---FEVGGAAPFNRTHRSKRSSSHPI 127
Query: 89 SRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEE 148
RGE +VCD+VS WV D+ TA D++G+EV VLGEV S +QYFFET+C+ N +
Sbjct: 128 FHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGEV-NINNSVFKQYFFETKCRDPNPVD 186
Query: 149 GGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTG 208
GCRG+D +HW S C ++V+ALT D + + WR+IRIDTACVC L +
Sbjct: 187 -------SGCRGIDSKHWNSYCTTTHTFVKALTMDGK-QAAWRFIRIDTACVCVLSRKAV 238
Query: 209 R 209
R
Sbjct: 239 R 239
>gi|119220598 apolipoprotein B48 receptor [Homo sapiens]
Length = 1088
Score = 35.0 bits (79), Expect = 0.046
Identities = 40/153 (26%), Positives = 56/153 (36%), Gaps = 22/153 (14%)
Query: 50 RGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSE--TAPASRRGELAVCDAVSGWVTDR 107
R AGP ++ A GA NR+R+ + T + GE + +G T
Sbjct: 591 RSLEAGPRHAGSVKPEASEAFPGAWENRTRKDMERGNTQEDAADGEQREEEETAGGQT-- 648
Query: 108 RTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAE---------EGGPGAGGGGC 158
A + G L EVP AGG L + C + E +G GA G C
Sbjct: 649 -LAAEAEGDRESELSEVPEAGGEGLTTQ--DAGCGTEEGEASVSENQELDGSTGADAGPC 705
Query: 159 RGVDRRHWVSECKAKQSYVRALTADAQGRVGWR 191
+ E A+++ AD R GWR
Sbjct: 706 PS------LGEAYARETEDEEAEADRTSRRGWR 732
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 34.3 bits (77), Expect = 0.079
Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 1/41 (2%)
Query: 17 LPSVPIESQPPPSTLPPFLA-PEWDLLSPRVVLSRGAPAGP 56
LP P+ PPP L PF + P+W L PR LS P P
Sbjct: 965 LPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSP 1005
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 33.1 bits (74), Expect = 0.18
Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 2 LPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAP-AGPPLLF 60
LPLP LP+ L LP+V P+ LPP L P + G P PP +
Sbjct: 1431 LPLP---LPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSML 1487
Query: 61 LLEAGAFRESAGAPANR 77
L+ R AGA R
Sbjct: 1488 SLDGPLVRPPAGAALGR 1504
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 32.7 bits (73), Expect = 0.23
Identities = 22/63 (34%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 123 EVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTA 182
E P A G RQ E A GG AG GCR V +CK + S RA++
Sbjct: 43 EEPGASGGARRQRGAE----AGQGARGGVAAGAEGCRPARLLGLVHDCKRRPSRARAVSR 98
Query: 183 DAQ 185
A+
Sbjct: 99 GAK 101
>gi|239754969 PREDICTED: hypothetical protein [Homo sapiens]
Length = 184
Score = 32.0 bits (71), Expect = 0.39
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%)
Query: 18 PSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANR 77
P++P + Q PP L PF P + L P PLLFL G+ + G+P +
Sbjct: 5 PAIPAQGQKPPQLLLPFPGSR-----PLLSLQPSTPPA-PLLFLGATGSSWNTPGSPRHT 58
Query: 78 SRRGVSETAP 87
+ AP
Sbjct: 59 PHPDMQTRAP 68
>gi|239749517 PREDICTED: hypothetical protein [Homo sapiens]
Length = 184
Score = 32.0 bits (71), Expect = 0.39
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%)
Query: 18 PSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANR 77
P++P + Q PP L PF P + L P PLLFL G+ + G+P +
Sbjct: 5 PAIPAQGQKPPQLLLPFPGSR-----PLLSLQPSTPPA-PLLFLGATGSSWNTPGSPRHT 58
Query: 78 SRRGVSETAP 87
+ AP
Sbjct: 59 PHPDMQTRAP 68
>gi|239743656 PREDICTED: hypothetical protein XP_002342923 [Homo
sapiens]
Length = 184
Score = 32.0 bits (71), Expect = 0.39
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 6/70 (8%)
Query: 18 PSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANR 77
P++P + Q PP L PF P + L P PLLFL G+ + G+P +
Sbjct: 5 PAIPAQGQKPPQLLLPFPGSR-----PLLSLQPSTPPA-PLLFLGATGSSWNTPGSPRHT 58
Query: 78 SRRGVSETAP 87
+ AP
Sbjct: 59 PHPDMQTRAP 68
>gi|122692281 hypothetical protein LOC645369 [Homo sapiens]
Length = 621
Score = 32.0 bits (71), Expect = 0.39
Identities = 29/112 (25%), Positives = 39/112 (34%), Gaps = 12/112 (10%)
Query: 18 PSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANR 77
P+ P +P + PP LA SPR P PP L +RE +G +R
Sbjct: 288 PAAPSGGRPRGAASPPDLAS-----SPR------CPREPPSLAEAVYSVYRERSGVAGSR 336
Query: 78 SRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGG 129
+ A AS A C W + TA + +P GG
Sbjct: 337 RAAAATAAAAASSCSSPAPCSPPESW-GRQSTASSFVDSSLSAFALLPLQGG 387
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,209,455
Number of Sequences: 37866
Number of extensions: 582830
Number of successful extensions: 3380
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 3170
Number of HSP's gapped (non-prelim): 184
length of query: 210
length of database: 18,247,518
effective HSP length: 98
effective length of query: 112
effective length of database: 14,536,650
effective search space: 1628104800
effective search space used: 1628104800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.