Search of human proteins with 5453796

Search of human proteins with 5453796

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453796 neuropeptide Y receptor Y5 [Homo sapiens]
         (445 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453796 neuropeptide Y receptor Y5 [Homo sapiens]                  902   0.0  
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]                  142   5e-34
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]                  132   6e-31
gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]         130   2e-30
gi|4502607 cholecystokinin A receptor [Homo sapiens]                  127   2e-29
gi|28875799 cholecystokinin B receptor [Homo sapiens]                 122   5e-28
gi|4758474 G protein-coupled receptor 10 [Homo sapiens]               116   5e-26
gi|222080109 orexin receptor 2 [Homo sapiens]                         115   8e-26
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]                 112   7e-25
gi|223633971 G protein-coupled receptor 83 [Homo sapiens]             112   9e-25
gi|222080095 orexin receptor 1 [Homo sapiens]                         110   3e-24
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]       109   6e-24
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]      109   6e-24
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]      109   6e-24
gi|21426829 prokineticin receptor 2 [Homo sapiens]                     99   1e-20
gi|20373179 G protein-coupled receptor 73 [Homo sapiens]               99   1e-20
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]           97   4e-20
gi|157738685 G protein-coupled receptor 103 [Homo sapiens]             96   5e-20
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec...    96   9e-20
gi|167000885 galanin receptor 1 [Homo sapiens]                         95   1e-19
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa...    92   1e-18
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]          90   5e-18
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]            89   6e-18
gi|62865887 G protein-coupled receptor 54 [Homo sapiens]               88   1e-17
gi|221139879 G protein-coupled receptor 63 [Homo sapiens]              87   4e-17
gi|13540557 G protein-coupled receptor 63 [Homo sapiens]               87   4e-17
gi|157426873 tachykinin receptor 2 [Homo sapiens]                      84   2e-16
gi|4505513 opiate receptor-like 1 [Homo sapiens]                       84   2e-16
gi|33286424 opiate receptor-like 1 [Homo sapiens]                      84   2e-16
gi|161484640 neuromedin B receptor [Homo sapiens]                      84   2e-16

>gi|5453796 neuropeptide Y receptor Y5 [Homo sapiens]
          Length = 445

 Score =  902 bits (2330), Expect = 0.0
 Identities = 445/445 (100%), Positives = 445/445 (100%)

Query: 1   MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL 60
           MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
Sbjct: 1   MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL 60

Query: 61  LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL 120
           LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
Sbjct: 61  LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL 120

Query: 121 QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL 180
           QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
Sbjct: 121 QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL 180

Query: 181 VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC 240
           VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
Sbjct: 181 VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC 240

Query: 241 GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP 300
           GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
Sbjct: 241 GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP 300

Query: 301 ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK 360
           ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
Sbjct: 301 ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK 360

Query: 361 KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL 420
           KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
Sbjct: 361 KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL 420

Query: 421 NPILYGFLNNGIKADLVSLIHCLHM 445
           NPILYGFLNNGIKADLVSLIHCLHM
Sbjct: 421 NPILYGFLNNGIKADLVSLIHCLHM 445


>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
          Length = 384

 Score =  142 bits (359), Expect = 5e-34
 Identities = 76/221 (34%), Positives = 124/221 (56%), Gaps = 11/221 (4%)

Query: 48  YTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQW 107
           Y  V +LG  GNL +++ ++K++  +   N LI NL+FSD+LV + C PFT    L+D W
Sbjct: 47  YGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHW 106

Query: 108 MFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLG 167
           +FG+ MC + PF+QCVS+ VS   L+ IA+ R+ +I +P        H Y  IA +W L 
Sbjct: 107 VFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVL- 165

Query: 168 FAICSPLPVFHSLVELQETFGSALLSS---RYLCVESWPSDSYRIAFTISLLLVQYILPL 224
            A+ S LP     V   E F +  L +   +Y+C + +PSDS+R+++T  LL++QY  PL
Sbjct: 166 -AVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPL 224

Query: 225 VCLTVSHTSVC------RSISCGLSNKENRLEENEMINLTL 259
             + + +  +        ++   + + + R  E + IN+ L
Sbjct: 225 CFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIML 265



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 29/67 (43%), Positives = 45/67 (67%)

Query: 370 LTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLN 429
           L  +++ FAV W+PL +F+ V D+N  +I+  +  L++ +CHL  M+S C+NPI YGFLN
Sbjct: 265 LLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLN 324

Query: 430 NGIKADL 436
              + DL
Sbjct: 325 KNFQRDL 331


>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
          Length = 381

 Score =  132 bits (332), Expect = 6e-31
 Identities = 68/201 (33%), Positives = 115/201 (57%), Gaps = 11/201 (5%)

Query: 39  DLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFT 98
           ++Q  LI  Y  + LLG +GN L++  ++K ++ +T  NF I NLA +D+LV   C PFT
Sbjct: 48  EVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFT 107

Query: 99  LTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYF 158
           LT  L+ +W  G V+CH++P+ Q ++V VST+ L  IA+ R+  I + + + ++    + 
Sbjct: 108 LTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFL 167

Query: 159 LIATVWTLGFAICSPLPVF--HSLVELQETFGSALLSSRYLCVESWPSDS---YRIAFTI 213
           +I   W +   + SPL +F  +SL+E+   F          C E WP +    Y   +++
Sbjct: 168 IIGLAWGISALLASPLAIFREYSLIEIIPDF------EIVACTEKWPGEEKSIYGTVYSL 221

Query: 214 SLLLVQYILPLVCLTVSHTSV 234
           S LL+ Y+LPL  ++ S+T +
Sbjct: 222 SSLLILYVLPLGIISFSYTRI 242



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 26/82 (31%), Positives = 49/82 (59%)

Query: 361 KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL 420
           +R +     L  +++VFAVSW+PLH F +  D +  ++  + +KL++ + H++ M S   
Sbjct: 261 QRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFA 320

Query: 421 NPILYGFLNNGIKADLVSLIHC 442
           NP+LYG++N+  +   +S   C
Sbjct: 321 NPLLYGWMNSNYRKAFLSAFRC 342


>gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]
          Length = 375

 Score =  130 bits (327), Expect = 2e-30
 Identities = 61/203 (30%), Positives = 109/203 (53%), Gaps = 3/203 (1%)

Query: 39  DLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFT 98
           D+  F++  Y+  +++G +GNL ++   ++++ +    N LI NLAFSD L+ L C P T
Sbjct: 39  DVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLT 98

Query: 99  LTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYF 158
               ++D W+FG+ +C +  F+QC+SV VS L L+ +A+ R+ +I +P     + +  Y 
Sbjct: 99  AVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYL 158

Query: 159 LIATVWTLGFAICSPL---PVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISL 215
            I  +W +   +  P     +  ++     +     L+ + +C ESWP   +R  +T  L
Sbjct: 159 GIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFL 218

Query: 216 LLVQYILPLVCLTVSHTSVCRSI 238
           LL QY LPL  + V +  + R +
Sbjct: 219 LLFQYCLPLGFILVCYARIYRRL 241



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 29/71 (40%), Positives = 48/71 (67%)

Query: 370 LTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLN 429
           L ++++ FAV W+PLH+F+ + D++   I   H  L++ +CHLL M S C+NP +YGFLN
Sbjct: 267 LVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLN 326

Query: 430 NGIKADLVSLI 440
              K ++ +L+
Sbjct: 327 TNFKKEIKALV 337


>gi|4502607 cholecystokinin A receptor [Homo sapiens]
          Length = 428

 Score =  127 bits (319), Expect = 2e-29
 Identities = 94/398 (23%), Positives = 172/398 (43%), Gaps = 59/398 (14%)

Query: 47  LYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQ 106
           LY+ + LL  +GN L++  L++ +  +T  N  + +LA SD+++ LFC PF L   LL  
Sbjct: 47  LYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKD 106

Query: 107 WMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNL--TANHGYFLIATVW 164
           ++FG  +C    +    SV VST  L++I++ RY  I  P+ + +  T +H   +IA  W
Sbjct: 107 FIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATW 166

Query: 165 TLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPL 224
            L F I +P P++ +LV   +         R+L     P+D  + ++   LLL+ +++P 
Sbjct: 167 CLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLL----PNDVMQQSWHTFLLLILFLIPG 222

Query: 225 VCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKK 284
           + + V++  +   +  G+  + ++ +           +K+  P    SG           
Sbjct: 223 IVMMVAYGLISLELYQGIKFEASQKKS----------AKERKPSTTSSG----------- 261

Query: 285 HRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEEN 344
              +Y     C L    RP ++   R L     S  +++ S                  N
Sbjct: 262 ---KYEDSDGCYL-QKTRPPRKLELRQLSTGSSSRANRIRS------------------N 299

Query: 345 SDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFK 404
           S    L  K+ V R+          L +++++F + WMP+   +    ++      R   
Sbjct: 300 SSAANLMAKKRVIRM----------LIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSG 349

Query: 405 LVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHC 442
                  LL   S C+NPI+Y F+N   +   ++   C
Sbjct: 350 TPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPC 387


>gi|28875799 cholecystokinin B receptor [Homo sapiens]
          Length = 447

 Score =  122 bits (307), Expect = 5e-28
 Identities = 96/394 (24%), Positives = 168/394 (42%), Gaps = 66/394 (16%)

Query: 45  IGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLL 104
           I LY  + L+   GN+LI++ L   R  +T  N  + +LA SD+L+ + C PFTL   L+
Sbjct: 58  ITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLM 117

Query: 105 DQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNL--TANHGYFLIAT 162
             ++FG V+C  + +L  VSV VSTL L++IA+ RY  I  P+   +  T +H   +I  
Sbjct: 118 GTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVA 177

Query: 163 VWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYIL 222
            W L   +  P PV+     + +  G  +L     CV  WPS   R  +++ LLL+ + +
Sbjct: 178 TWLLSGLLMVPYPVY----TVVQPVGPRVLQ----CVHRWPSARVRQTWSVLLLLLLFFI 229

Query: 223 PLVCLTVSHTSVCRSISCGL-------SNKENRLEENEMINLTLHPSKKSGPQVKLSGSH 275
           P V + V++  + R +  GL       S+ ++R+     +   +H + +  P+    G  
Sbjct: 230 PGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGED 289

Query: 276 KWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPT 335
                      R   + TA   P P   S+   +++L                       
Sbjct: 290 SDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLL----------------------- 326

Query: 336 CFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFND 395
                            K+ V R+          L +++++F + W+P++  +    F+ 
Sbjct: 327 ----------------AKKRVVRM----------LLVIVVLFFLCWLPVYSANTWRAFDG 360

Query: 396 NLISNRHFKLVYCICHLLGMMSCCLNPILYGFLN 429
                          HLL   S C+NP++Y F++
Sbjct: 361 PGAHRALSGAPISFIHLLSYASACVNPLVYCFMH 394


>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
          Length = 370

 Score =  116 bits (290), Expect = 5e-26
 Identities = 71/229 (31%), Positives = 116/229 (50%), Gaps = 11/229 (4%)

Query: 10  NKTLATENNTAATRNSDFPVWDDYKSS--VDDLQYFLIGLYTFVSLLGFMGNLLILMALM 67
           N++        +   +D P    ++S   V  L+  ++ LY+ V ++G +GN L+++ + 
Sbjct: 27  NQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIA 86

Query: 68  KKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQ-WMFGKVMCHIMPFLQCVSVL 126
           + R      NFLIGNLA SD+L+   C P TL      + W+FG  +CH++ FLQ V+V 
Sbjct: 87  RVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVY 146

Query: 127 VSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQET 186
           VS   L +IA+ RY ++ HP+   ++     + +  +W L   +  P  V    VEL+  
Sbjct: 147 VSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKP- 205

Query: 187 FGSALLSSRYLCVESWPS-DSYRIAFTISLLLVQYILPLVCLTVSHTSV 234
                     LC E W S +  R  +   LLLV Y+LPL+ + +S+  V
Sbjct: 206 ------HDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRV 248



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 30/81 (37%), Positives = 50/81 (61%)

Query: 360 KKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCC 419
           + R R  F  L ++++VFAV W+PLH+F+++ D + + I    F LV  +CH L M S C
Sbjct: 270 RARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSAC 329

Query: 420 LNPILYGFLNNGIKADLVSLI 440
            NP +Y +L++  + +L  L+
Sbjct: 330 YNPFIYAWLHDSFREELRKLL 350


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score =  115 bits (288), Expect = 8e-26
 Identities = 65/214 (30%), Positives = 113/214 (52%), Gaps = 6/214 (2%)

Query: 29  VWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDI 88
           +W +Y     + ++ LI  Y  V ++  +GN+L+ +A+ K  + +T  N+ I NL+ +D+
Sbjct: 43  LWREYLHP-KEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADV 101

Query: 89  LVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPIS 148
           LV + C P TL   + + W FG+ +C ++P+LQ VSV VS L L  IA+ R++ I HP+ 
Sbjct: 102 LVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLM 161

Query: 149 NNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETF-GSALLSSRY-LCVESWPSDS 206
              TA      I  +W +   I  P  +   ++E    F G A  ++ + +C E W  + 
Sbjct: 162 FKSTAKRARNSIVIIWIVSCIIMIPQAI---VMECSTVFPGLANKTTLFTVCDERWGGEI 218

Query: 207 YRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC 240
           Y   + I   LV Y+ PL  + +++  + R + C
Sbjct: 219 YPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWC 252



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 26/115 (22%), Positives = 50/115 (43%), Gaps = 14/115 (12%)

Query: 331 PGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVV 390
           PG PT   +     +++ ++R +R   R+          L I++LVFA+ ++P+ + +V+
Sbjct: 278 PGQPTKSRMSAVA-AEIKQIRARRKTARM----------LMIVLLVFAICYLPISILNVL 326

Query: 391 TDFNDNLISNRHFKLVYC---ICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHC 442
                        + VY      H L   +   NPI+Y FL+   + +  +   C
Sbjct: 327 KRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSC 381


>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
          Length = 430

 Score =  112 bits (280), Expect = 7e-25
 Identities = 68/227 (29%), Positives = 104/227 (45%), Gaps = 10/227 (4%)

Query: 18  NTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVN 77
           NT AT  ++      Y+ +      F++  Y  + LL  +GN L+   ++K R+  T  N
Sbjct: 21  NTEATPATNLTFSSYYQHTSPVAAMFIVA-YALIFLLCMVGNTLVCFIVLKNRHMHTVTN 79

Query: 78  FLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAI 137
             I NLA SD+LV +FC P TL   L+  W F    C +   +Q +SV  S   L++IA+
Sbjct: 80  MFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAV 139

Query: 138 VRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSR-- 195
            R+  I HP    LT       IA +W L   I  P  V  ++   +  F   ++ +R  
Sbjct: 140 ERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHF---MVDARNR 196

Query: 196 ----YLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSI 238
               Y C E+WP    R  +T  L    Y+ PL  + V +  + R +
Sbjct: 197 SYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKL 243



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 22/78 (28%), Positives = 35/78 (44%), Gaps = 2/78 (2%)

Query: 358 RIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYC--ICHLLGM 415
           R  +R   V + L ++ L F +SW+PL    ++ D+        H   VY     H L  
Sbjct: 260 RASRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAF 319

Query: 416 MSCCLNPILYGFLNNGIK 433
            +   NPI+YG+ N   +
Sbjct: 320 FNSSANPIIYGYFNENFR 337


>gi|223633971 G protein-coupled receptor 83 [Homo sapiens]
          Length = 423

 Score =  112 bits (279), Expect = 9e-25
 Identities = 64/225 (28%), Positives = 114/225 (50%), Gaps = 14/225 (6%)

Query: 24  NSDFPVWDDY--------KSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTT 75
           N  F  W ++        +S    ++  LI  Y+F+ +    GN+L+   + K +   + 
Sbjct: 46  NYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSA 105

Query: 76  VNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISI 135
            +  I NLA +DI++ L  +PFTL   +   W+FGK MCH+  F Q  S+ VS L L +I
Sbjct: 106 TSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAI 165

Query: 136 AIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSR 195
           A+ R+ +I HP+   ++   G   IA +WT+      P    H++ +   TF  +    R
Sbjct: 166 AVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLP----HAICQKLFTFKYSEDIVR 221

Query: 196 YLCVESW--PSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSI 238
            LC+  +  P+D +     ++  ++ YILPL+ ++V++  V + +
Sbjct: 222 SLCLPDFPEPADLFWKYLDLATFILLYILPLLIISVAYARVAKKL 266



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 19/82 (23%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 359 IKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSC 418
           ++++ +     L +++++FA+ W PL+ + ++        +N     +Y   H   M S 
Sbjct: 283 LRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLLSSKVIRTNNA----LYFAFHWFAMSST 338

Query: 419 CLNPILYGFLNNGIKADLVSLI 440
           C NP +Y +LN   + +L +L+
Sbjct: 339 CYNPFIYCWLNENFRIELKALL 360


>gi|222080095 orexin receptor 1 [Homo sapiens]
          Length = 425

 Score =  110 bits (274), Expect = 3e-24
 Identities = 63/211 (29%), Positives = 104/211 (49%), Gaps = 4/211 (1%)

Query: 29  VWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDI 88
           +W DY       ++ LI  Y  V ++  +GN L+ +A+ +  + +T  N+ I NL+ +D+
Sbjct: 35  LWRDYLYP-KQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADV 93

Query: 89  LVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPIS 148
           LV   C P +L   + + W+FG  +C ++P+LQ VSV V+ L L  IA+ R++ I HP+ 
Sbjct: 94  LVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLL 153

Query: 149 NNLTANHGYFLIATVWTLGFAICSP-LPVFHSLVELQETFGSALLSSRYLCVESWPSDSY 207
              TA      I  +W +  AI  P   V      L E      L S  +C E W  D Y
Sbjct: 154 FKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANRTRLFS--VCDERWADDLY 211

Query: 208 RIAFTISLLLVQYILPLVCLTVSHTSVCRSI 238
              +     +V Y+ PL  + +++  + R +
Sbjct: 212 PKIYHSCFFIVTYLAPLGLMAMAYFQIFRKL 242



 Score = 32.3 bits (72), Expect = 0.89
 Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 13/101 (12%)

Query: 345 SDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFK 404
           ++V ++R +R   ++          L +++LVFA+ ++P+ + +V+             +
Sbjct: 285 AEVKQMRARRKTAKM----------LMVVLLVFALCYLPISVLNVLKRVFGMFRQASDRE 334

Query: 405 LVYC---ICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHC 442
            VY      H L   +   NPI+Y FL+   +    +   C
Sbjct: 335 AVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAFSC 375


>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
          Length = 420

 Score =  109 bits (272), Expect = 6e-24
 Identities = 60/190 (31%), Positives = 92/190 (48%), Gaps = 8/190 (4%)

Query: 48  YTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQW 107
           Y  +  L  MGN ++   +M+ ++  T  N  I NLA SD+LV +FC P TL   ++  W
Sbjct: 52  YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGW 111

Query: 108 MFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLG 167
            FG  MC I   +Q +SV  S   L++IA+ R+  + +P    LT    + +I  +W L 
Sbjct: 112 PFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLA 171

Query: 168 FAICSPLPVFHSLVELQETFGSALLSSR------YLCVESWPSDSYRIAFTISLLLVQYI 221
             I SP  V   + E  E +    L+S+      Y C E WP+   R  +T  L    Y+
Sbjct: 172 ITIMSPSAVMLHVQE--EKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYL 229

Query: 222 LPLVCLTVSH 231
            PL  + + +
Sbjct: 230 APLSLIVIMY 239



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 6/79 (7%)

Query: 359 IKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKL----VYCICHLLG 414
           + ++ + +   L I+ L+F +SW+PL    +++D+ D  +S    ++    +Y   H L 
Sbjct: 265 VSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYAD--LSPNELQIINIYIYPFAHWLA 322

Query: 415 MMSCCLNPILYGFLNNGIK 433
             +  +NPI+YGF N   +
Sbjct: 323 FGNSSVNPIIYGFFNENFR 341


>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
          Length = 522

 Score =  109 bits (272), Expect = 6e-24
 Identities = 60/190 (31%), Positives = 92/190 (48%), Gaps = 8/190 (4%)

Query: 48  YTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQW 107
           Y  +  L  MGN ++   +M+ ++  T  N  I NLA SD+LV +FC P TL   ++  W
Sbjct: 154 YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGW 213

Query: 108 MFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLG 167
            FG  MC I   +Q +SV  S   L++IA+ R+  + +P    LT    + +I  +W L 
Sbjct: 214 PFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLA 273

Query: 168 FAICSPLPVFHSLVELQETFGSALLSSR------YLCVESWPSDSYRIAFTISLLLVQYI 221
             I SP  V   + E  E +    L+S+      Y C E WP+   R  +T  L    Y+
Sbjct: 274 ITIMSPSAVMLHVQE--EKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYL 331

Query: 222 LPLVCLTVSH 231
            PL  + + +
Sbjct: 332 APLSLIVIMY 341



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 6/79 (7%)

Query: 359 IKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKL----VYCICHLLG 414
           + ++ + +   L I+ L+F +SW+PL    +++D+ D  +S    ++    +Y   H L 
Sbjct: 367 VSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYAD--LSPNELQIINIYIYPFAHWLA 424

Query: 415 MMSCCLNPILYGFLNNGIK 433
             +  +NPI+YGF N   +
Sbjct: 425 FGNSSVNPIIYGFFNENFR 443


>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
          Length = 423

 Score =  109 bits (272), Expect = 6e-24
 Identities = 60/190 (31%), Positives = 92/190 (48%), Gaps = 8/190 (4%)

Query: 48  YTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQW 107
           Y  +  L  MGN ++   +M+ ++  T  N  I NLA SD+LV +FC P TL   ++  W
Sbjct: 55  YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGW 114

Query: 108 MFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLG 167
            FG  MC I   +Q +SV  S   L++IA+ R+  + +P    LT    + +I  +W L 
Sbjct: 115 PFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLA 174

Query: 168 FAICSPLPVFHSLVELQETFGSALLSSR------YLCVESWPSDSYRIAFTISLLLVQYI 221
             I SP  V   + E  E +    L+S+      Y C E WP+   R  +T  L    Y+
Sbjct: 175 ITIMSPSAVMLHVQE--EKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYL 232

Query: 222 LPLVCLTVSH 231
            PL  + + +
Sbjct: 233 APLSLIVIMY 242



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 6/79 (7%)

Query: 359 IKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKL----VYCICHLLG 414
           + ++ + +   L I+ L+F +SW+PL    +++D+ D  +S    ++    +Y   H L 
Sbjct: 268 VSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYAD--LSPNELQIINIYIYPFAHWLA 325

Query: 415 MMSCCLNPILYGFLNNGIK 433
             +  +NPI+YGF N   +
Sbjct: 326 FGNSSVNPIIYGFFNENFR 344


>gi|21426829 prokineticin receptor 2 [Homo sapiens]
          Length = 384

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 66/227 (29%), Positives = 110/227 (48%), Gaps = 24/227 (10%)

Query: 26  DFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFM-----GNLLILMALMKKRNQKTTVNFLI 80
           D P+ D+ +       +F   +   ++L G M     GN + + AL + +  +   N LI
Sbjct: 34  DLPM-DEDEDMTKTRTFFAAKIVIGIALAGIMLVCGIGNFVFIAALTRYKKLRNLTNLLI 92

Query: 81  GNLAFSDILVVLFCSPFTLTSVLLDQ--WMFGKVMCHIMPFLQCVSVLVSTLILISIAIV 138
            NLA SD LV + C PF +   ++ Q  W  G V+C  + +L+ VS+ VST  L++IAI 
Sbjct: 93  ANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAID 152

Query: 139 RYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHS-----LVELQETFGSALLS 193
           RY  I HP+   +      FLIA VW +   I  P   F +     +V+ QE        
Sbjct: 153 RYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIPSAYFATETVLFIVKSQE-------- 204

Query: 194 SRYLCVESWPSDS--YRIAFTISLLLVQYILPLVCLTVSHTSVCRSI 238
            +  C + WP D   Y  ++ + +  V+++ P+V +T+ +  + R +
Sbjct: 205 -KIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTMTLCYARISREL 250



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 8/79 (10%)

Query: 358 RIKKRSRSVFYRLTILILV-----FAVSWMPLHLFHVVTDFNDNL-ISNRHFKLVYCICH 411
           +I+KR R    R T+L+L+     + + W P + F +V DF   + +  +H+   + +  
Sbjct: 262 QIRKRLRC--RRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYVVE 319

Query: 412 LLGMMSCCLNPILYGFLNN 430
            + M +  +N + +  + N
Sbjct: 320 CIAMSNSMINTVCFVTVKN 338


>gi|20373179 G protein-coupled receptor 73 [Homo sapiens]
          Length = 393

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 65/227 (28%), Positives = 113/227 (49%), Gaps = 24/227 (10%)

Query: 26  DFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFM-----GNLLILMALMKKRNQKTTVNFLI 80
           D P+ D+ +   +   +F   +   ++L+G M     GN + + AL++ +  +   N LI
Sbjct: 43  DMPL-DEDEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALVRYKKLRNLTNLLI 101

Query: 81  GNLAFSDILVVLFCSPFTLTSVLLDQ--WMFGKVMCHIMPFLQCVSVLVSTLILISIAIV 138
            NLA SD LV + C PF +   ++ Q  W  G V+C  + +L+ VS+ VST  L++IAI 
Sbjct: 102 ANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCTSVNYLRTVSLYVSTNALLAIAID 161

Query: 139 RYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHS-----LVELQETFGSALLS 193
           RY  I HP+   +       LIA VWT+   I  P   F +     +V+ QE        
Sbjct: 162 RYLAIVHPLRPRMKCQTATGLIALVWTVSILIAIPSAYFTTETVLVIVKSQE-------- 213

Query: 194 SRYLCVESWPSDS--YRIAFTISLLLVQYILPLVCLTVSHTSVCRSI 238
            +  C + WP D   Y  ++ + +  ++++ P+V +T+ +  + R +
Sbjct: 214 -KIFCGQIWPVDQQLYYKSYFLFIFGIEFVGPVVTMTLCYARISREL 259



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 8/79 (10%)

Query: 358 RIKKRSRSVFYRLTILILV-----FAVSWMPLHLFHVVTDFNDNL-ISNRHFKLVYCICH 411
           +I+KR R    R T+L+L+     + + W P + F +V DF   + +  +H+   + I  
Sbjct: 271 QIRKRLRC--RRKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPTVFVKEKHYLTAFYIVE 328

Query: 412 LLGMMSCCLNPILYGFLNN 430
            + M +  +N + +  + N
Sbjct: 329 CIAMSNSMINTLCFVTVKN 347


>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
          Length = 384

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 58/244 (23%), Positives = 124/244 (50%), Gaps = 21/244 (8%)

Query: 1   MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL 60
           ++LE+D + +  +++ +       +D PV DD+  S   + Y +  +Y  + L+G +GN+
Sbjct: 9   LNLEVDHFMHCNISSHS-------ADLPVNDDW--SHPGILYVIPAVYGVIILIGLIGNI 59

Query: 61  LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL 120
            ++      ++ +   N  I +LA  D+L+++ C+P   +  L D+W+FG++ C ++PF+
Sbjct: 60  TLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFI 119

Query: 121 QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLI----ATVWTLGFAICSPLPV 176
           Q  SV VS   L +++  RY  I  P+  ++ A+H    I    A +W +   +  P  V
Sbjct: 120 QLTSVGVSVFTLTALSADRYKAIVRPM--DIQASHALMKICLKAAFIWIISMLLAIPEAV 177

Query: 177 FHSLVELQETFGSALLSSRYLCVESWP--SDSYRIAFTISLLLVQYILPLVCLTVSHTSV 234
           F  L      F     +  ++    +P  ++ +    +++  LV Y++PL  ++V +  +
Sbjct: 178 FSDL----HPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFI 233

Query: 235 CRSI 238
            +++
Sbjct: 234 AKNL 237



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 19/94 (20%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 350 LRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCI 409
           + VK+ +   K+ +++V     + + +FA  W+P H+ ++   ++ + +       V  I
Sbjct: 250 IHVKKQIESRKRLAKTVL----VFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSI 305

Query: 410 C-HLLGMMSCCLNPILYGFLNNGIKADLVSLIHC 442
           C  LL   + C+NP     L+   +    + + C
Sbjct: 306 CARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLC 339


>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
          Length = 431

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 50/197 (25%), Positives = 98/197 (49%), Gaps = 7/197 (3%)

Query: 40  LQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTL 99
           L   L G+  F   L   GN L+   + + +  +T  N  I +LA SD+L+  FC P T+
Sbjct: 46  LALVLTGVLIFA--LALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTM 103

Query: 100 TSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISN--NLTANHGY 157
              + D W+ G  +C ++PF+Q  +V+   L +  IA+ R+  + HP       T    +
Sbjct: 104 LQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAF 163

Query: 158 FLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLL 217
            ++  VW +   + SP+  +H + +L+  +          C+E W S  ++  +T  +L+
Sbjct: 164 TMLGVVWLVAVIVGSPM--WH-VQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILV 220

Query: 218 VQYILPLVCLTVSHTSV 234
           + ++LPL+ + + ++ +
Sbjct: 221 ILFLLPLMVMLILYSKI 237



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 24/87 (27%), Positives = 52/87 (59%), Gaps = 4/87 (4%)

Query: 360 KKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFN--DNLISNRHFKLVYCICHLLGMMS 417
           +K+ R+V   +T++ L FAV W P H+ H++ +++  +    +   K+++ I  ++G  +
Sbjct: 266 RKKKRAVIMMVTVVAL-FAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSN 324

Query: 418 CCLNPILYGFLNNGIKADLVSLI-HCL 443
              NPI+Y F+N   K +++S + +C+
Sbjct: 325 SICNPIVYAFMNENFKKNVLSAVCYCI 351


>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
           receptor [Homo sapiens]
          Length = 368

 Score = 95.5 bits (236), Expect = 9e-20
 Identities = 55/224 (24%), Positives = 115/224 (51%), Gaps = 14/224 (6%)

Query: 21  ATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLI 80
           ++ ++D PV DD+  S   + Y +  +Y  + L+G +GN+ ++      ++ +   N  I
Sbjct: 6   SSHSADLPVNDDW--SHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFI 63

Query: 81  GNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRY 140
            +LA  D+L+++ C+P   +  L D+W+FG++ C ++PF+Q  SV VS   L +++  RY
Sbjct: 64  SSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRY 123

Query: 141 HMIKHPISNNLTANHGYFLI----ATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRY 196
             I  P+  ++ A+H    I    A +W +   +  P  VF  L      F     +  +
Sbjct: 124 KAIVRPM--DIQASHALMKICLKAAFIWIISMLLAIPEAVFSDL----HPFHEESTNQTF 177

Query: 197 LCVESWP--SDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSI 238
           +    +P  ++ +    +++  LV Y++PL  ++V +  + +++
Sbjct: 178 ISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNL 221



 Score = 36.2 bits (82), Expect = 0.062
 Identities = 19/94 (20%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 350 LRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCI 409
           + VK+ +   K+ +++V     + + +FA  W+P H+ ++   ++ + +       V  I
Sbjct: 234 IHVKKQIESRKRLAKTVL----VFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSI 289

Query: 410 C-HLLGMMSCCLNPILYGFLNNGIKADLVSLIHC 442
           C  LL   + C+NP     L+   +    + + C
Sbjct: 290 CARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLC 323


>gi|167000885 galanin receptor 1 [Homo sapiens]
          Length = 349

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 62/223 (27%), Positives = 106/223 (47%), Gaps = 19/223 (8%)

Query: 43  FLIGLYTFVSL--------LGFMGNLLILMALMKKRNQK--TTVNFLIGNLAFSDILVVL 92
           F IG+  FV+L        LG +GN L++  L + +  K  +T N  I NL+ +D+  +L
Sbjct: 27  FGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLL 86

Query: 93  FCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHP-ISNNL 151
           FC PF  T   L  W+ G  +C  + +   VS+LVS   L ++++ RY  I H   S++L
Sbjct: 87  FCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSL 146

Query: 152 TANHGYFL-IATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIA 210
             +    L +  +W L  A+ SP+     L   +        S++  C E WP   ++ A
Sbjct: 147 RVSRNALLGVGCIWALSIAMASPVAYHQGLFHPR-------ASNQTFCWEQWPDPRHKKA 199

Query: 211 FTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENE 253
           + +   +  Y+LPL+ +   +  V   +   L N   + E ++
Sbjct: 200 YVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASK 242



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 353 KRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHL 412
           K+S    KK +++V     ++++VF +SW+P H+ H+  +F    ++   F L     H 
Sbjct: 236 KKSEASKKKTAQTVL----VVVVVFGISWLPHHIIHLWAEFGVFPLTPASF-LFRITAHC 290

Query: 413 LGMMSCCLNPILYGFLNNGIKADLVSLIHC 442
           L   +  +NPI+Y FL+   +     +  C
Sbjct: 291 LAYSNSSVNPIIYAFLSENFRKAYKQVFKC 320


>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
           sapiens]
          Length = 422

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 100/425 (23%), Positives = 170/425 (40%), Gaps = 51/425 (12%)

Query: 32  DYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVV 91
           D   S   +   L+G   F ++LG   N  ++ A+  +R+ +   N+LIG+LA +D++V 
Sbjct: 30  DVTVSYQVITSLLLGTLIFCAVLG---NACVVAAIALERSLQNVANYLIGSLAVTDLMVS 86

Query: 92  LFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPIS--N 149
           +   P      +L++W  G+V C +   L  +    S L L +IA+ RY  I  PI   N
Sbjct: 87  VLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVN 146

Query: 150 NLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRI 209
             T      LI+  W +GF I  P  +     E +    +  +S  +             
Sbjct: 147 KRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDH------------- 193

Query: 210 AFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQV 269
            +TI      + +PL+ + V +  + R+    +     ++E+               PQ 
Sbjct: 194 GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKT---GADTRHGASPAPQP 250

Query: 270 KL-----SGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILP----ENFGSVR 320
           K      SGS  W        R     K    L A     Q +    L        G+ +
Sbjct: 251 KKSVNGESGSRNW--------RLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSK 302

Query: 321 SQLSSSSKF--IPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFA 378
             L   S+    P  P  FE K E N+   E + K ++ R +K  ++    L I++  F 
Sbjct: 303 EHLPLPSEAGPTPCAPASFERKNERNA---EAKRKMALARERKTVKT----LGIIMGTFI 355

Query: 379 VSWMPLHLFHVVTDFNDNLISNRHF-KLVYCICHLLGMMSCCLNPILYGFLNNGIKADLV 437
           + W+P  +  +V  F +   S+ H   L+  I + LG  +  LNP++Y + N   +    
Sbjct: 356 LCWLPFFIVALVLPFCE---SSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFK 412

Query: 438 SLIHC 442
            +I C
Sbjct: 413 KIIKC 417


>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
          Length = 414

 Score = 89.7 bits (221), Expect = 5e-18
 Identities = 95/422 (22%), Positives = 174/422 (41%), Gaps = 44/422 (10%)

Query: 32  DYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVV 91
           D K+      Y+   L   ++++ F GN+L+ MA+ +++  +TT N+LI +LA +D+LV 
Sbjct: 26  DGKADRPHYNYYATLLTLLIAVIVF-GNVLVCMAVSREKALQTTTNYLIVSLAVADLLVA 84

Query: 92  LFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNL 151
               P+ +   ++ +W F ++ C I   L  +    S L L +I+I RY  +  P+  N 
Sbjct: 85  TLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNT 144

Query: 152 ---TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYR 208
              +      +I+ VW L F I  PL     L  L     +  + +    V      S+ 
Sbjct: 145 RYSSKRRVTVMISIVWVLSFTISCPL-----LFGLNNADQNECIIANPAFVVYSSIVSFY 199

Query: 209 IAFTISLLLVQYILPLVCLTVSHTSVCRS-------ISCGLSNKENRLEENEMINLTLHP 261
           + F ++LL+   I  ++       +  RS       +   L     R +E EM  L    
Sbjct: 200 VPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKEAARRAQELEMEML---- 255

Query: 262 SKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRS 321
           S  S P+       +  YS I     + +      LP P      +H  +        + 
Sbjct: 256 SSTSPPE-------RTRYSPIPPSHHQLT------LPDP------SHHGLHSTPDSPAKP 296

Query: 322 QLSSSSKFIPGVPTCFEIKPEENSDVH-ELRVKRSVTRIKKRSRSVFYRLTILILVFAVS 380
           + +  +K  P +   FEI+   N      L+        +++ +     L I++ VF + 
Sbjct: 297 EKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIIC 356

Query: 381 WMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLI 440
           W+P  + H++    D  I      ++Y     LG ++  +NPI+Y   N   +   + ++
Sbjct: 357 WLPFFITHILNIHCDCNIP----PVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKIL 412

Query: 441 HC 442
           HC
Sbjct: 413 HC 414


>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
          Length = 443

 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 94/434 (21%), Positives = 179/434 (41%), Gaps = 39/434 (8%)

Query: 32  DYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVV 91
           D K+      Y+   L   ++++ F GN+L+ MA+ +++  +TT N+LI +LA +D+LV 
Sbjct: 26  DGKADRPHYNYYATLLTLLIAVIVF-GNVLVCMAVSREKALQTTTNYLIVSLAVADLLVA 84

Query: 92  LFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNL 151
               P+ +   ++ +W F ++ C I   L  +    S L L +I+I RY  +  P+  N 
Sbjct: 85  TLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNT 144

Query: 152 ---TANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYR 208
              +      +I+ VW L F I  PL     L  L     +  + +    V      S+ 
Sbjct: 145 RYSSKRRVTVMISIVWVLSFTISCPL-----LFGLNNADQNECIIANPAFVVYSSIVSFY 199

Query: 209 IAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPS--KKSG 266
           + F ++LL+   I  ++       +  RS     ++    L+ N       HP   K   
Sbjct: 200 VPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGN-----CTHPEDMKLCT 254

Query: 267 PQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENF---------- 316
             +K +GS   +   ++  RR    +   +L +   P +  +S I P +           
Sbjct: 255 VIMKSNGSFPVNRRRVEAARRAQELEME-MLSSTSPPERTRYSPIPPSHHQLTLPDPSHH 313

Query: 317 -------GSVRSQLSSSSKFIPGVPTCFEIKPEENSDVH-ELRVKRSVTRIKKRSRSVFY 368
                     + + +  +K  P +   FEI+   N      L+        +++ +    
Sbjct: 314 GLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQ 373

Query: 369 RLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFL 428
            L I++ VF + W+P  + H++    D  I      ++Y     LG ++  +NPI+Y   
Sbjct: 374 MLAIVLGVFIICWLPFFITHILNIHCDCNIP----PVLYSAFTWLGYVNSAVNPIIYTTF 429

Query: 429 NNGIKADLVSLIHC 442
           N   +   + ++HC
Sbjct: 430 NIEFRKAFLKILHC 443


>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
          Length = 398

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 51/193 (26%), Positives = 93/193 (48%), Gaps = 12/193 (6%)

Query: 48  YTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQW 107
           +  + LLG +GN L++  + + +  +T  NF I NLA +D+  +L C PFT     L  W
Sbjct: 49  FAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALLYPLPGW 108

Query: 108 MFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPIS--NNLTANHGYFLIATVWT 165
           + G  MC  + ++Q VSV  +   L ++++ R+++   P+   +  T      +  ++W 
Sbjct: 109 VLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWV 168

Query: 166 LGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLV 225
              A+ +P+   H L              R  C E++PS +   AF +  LL  Y+LPL+
Sbjct: 169 GSAAVSAPVLALHRLSP----------GPRAYCSEAFPSRALERAFALYNLLALYLLPLL 218

Query: 226 CLTVSHTSVCRSI 238
                + ++ R +
Sbjct: 219 ATCACYAAMLRHL 231



 Score = 31.2 bits (69), Expect = 2.0
 Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 3/61 (4%)

Query: 373 LILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCI---CHLLGMMSCCLNPILYGFLN 429
           ++L+FA  W P+ LF V+         +      Y +    H +   +  LNP+LY FL 
Sbjct: 268 VVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWAHCMSYSNSALNPLLYAFLG 327

Query: 430 N 430
           +
Sbjct: 328 S 328


>gi|221139879 G protein-coupled receptor 63 [Homo sapiens]
          Length = 419

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 51/206 (24%), Positives = 100/206 (48%), Gaps = 9/206 (4%)

Query: 33  YKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVL 92
           +KS    LQ  L  +  F+  + F+GNL++ + + +K   ++ +N L+ +LAF+D+L+ +
Sbjct: 73  FKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAV 132

Query: 93  FCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLT 152
              PF L ++L  +W+FGK  C +      + V+    IL+ I+I R+ +I     + L 
Sbjct: 133 LNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQR-QDKLN 191

Query: 153 ANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFT 212
                 LIA  W   F +  PL V +  +++         S    CV  + ++    A+ 
Sbjct: 192 PYRAKVLIAVSWATSFCVAFPLAVGNPDLQIP--------SRAPQCVFGYTTNPGYQAYV 243

Query: 213 ISLLLVQYILPLVCLTVSHTSVCRSI 238
           I + L+ + +P + +  S   +  ++
Sbjct: 244 ILISLISFFIPFLVILYSFMGILNTL 269


>gi|13540557 G protein-coupled receptor 63 [Homo sapiens]
          Length = 419

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 51/206 (24%), Positives = 100/206 (48%), Gaps = 9/206 (4%)

Query: 33  YKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVL 92
           +KS    LQ  L  +  F+  + F+GNL++ + + +K   ++ +N L+ +LAF+D+L+ +
Sbjct: 73  FKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAV 132

Query: 93  FCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLT 152
              PF L ++L  +W+FGK  C +      + V+    IL+ I+I R+ +I     + L 
Sbjct: 133 LNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQR-QDKLN 191

Query: 153 ANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFT 212
                 LIA  W   F +  PL V +  +++         S    CV  + ++    A+ 
Sbjct: 192 PYRAKVLIAVSWATSFCVAFPLAVGNPDLQIP--------SRAPQCVFGYTTNPGYQAYV 243

Query: 213 ISLLLVQYILPLVCLTVSHTSVCRSI 238
           I + L+ + +P + +  S   +  ++
Sbjct: 244 ILISLISFFIPFLVILYSFMGILNTL 269


>gi|157426873 tachykinin receptor 2 [Homo sapiens]
          Length = 398

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 49/190 (25%), Positives = 89/190 (46%), Gaps = 12/190 (6%)

Query: 48  YTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQW 107
           Y  + L+   GN +++  ++  R  +T  N+ I NLA +D+ +  F + F       + W
Sbjct: 40  YLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIW 99

Query: 108 MFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLG 167
            FG+  C+        ++ VS   + +IA  RY  I HP    L+A     +IA +W + 
Sbjct: 100 YFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVA 159

Query: 168 FAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDS---YRIAFTISLLLVQYILPL 224
            A+ SP   F+S V + +            CV +WP DS     + + + ++ + Y LPL
Sbjct: 160 LALASP-QCFYSTVTMDQ--------GATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPL 210

Query: 225 VCLTVSHTSV 234
             + V+++ +
Sbjct: 211 AVMFVAYSVI 220



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 20/73 (27%), Positives = 39/73 (53%)

Query: 370 LTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLN 429
           + +++L FA+ W+P HL+ ++  F +++  ++  + VY     L M S   NPI+Y  LN
Sbjct: 252 MVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLN 311

Query: 430 NGIKADLVSLIHC 442
           +  ++       C
Sbjct: 312 HRFRSGFRLAFRC 324


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 56/202 (27%), Positives = 99/202 (49%), Gaps = 12/202 (5%)

Query: 40  LQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTL 99
           L+  ++GLY  V + G +GN L++  +++    KT  N  I NLA +D LV+L   PF  
Sbjct: 50  LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL-TLPFQG 108

Query: 100 TSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPIS--NNLTANHGY 157
           T +LL  W FG  +C  +  +   ++  ST  L ++++ RY  I HPI   +  T++   
Sbjct: 109 TDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQ 168

Query: 158 FLIATVWTLGFAICSPLPVFHSL-VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLL 216
            +   +W L   +  P+ +  S  VE +E           L     P D +   F I + 
Sbjct: 169 AVNVAIWALASVVGVPVAIMGSAQVEDEEI--------ECLVEIPTPQDYWGPVFAICIF 220

Query: 217 LVQYILPLVCLTVSHTSVCRSI 238
           L  +I+P++ ++V ++ + R +
Sbjct: 221 LFSFIVPVLVISVCYSLMIRRL 242



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 347 VHELRVKRSVTRIKKRSRSVFYRLTILILV----FAVSWMPLHLFHVVTDFNDNLISNRH 402
           +  LR  R ++  +++ R++  R+T L+LV    F   W P+ +F +         S   
Sbjct: 239 IRRLRGVRLLSGSREKDRNL-RRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETA 297

Query: 403 FKLVYCICHLLGMMSCCLNPILYGFLNNGIKA 434
             ++   C  LG ++ CLNPILY FL+   KA
Sbjct: 298 VAILR-FCTALGYVNSCLNPILYAFLDENFKA 328


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 56/202 (27%), Positives = 99/202 (49%), Gaps = 12/202 (5%)

Query: 40  LQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTL 99
           L+  ++GLY  V + G +GN L++  +++    KT  N  I NLA +D LV+L   PF  
Sbjct: 50  LKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLL-TLPFQG 108

Query: 100 TSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPIS--NNLTANHGY 157
           T +LL  W FG  +C  +  +   ++  ST  L ++++ RY  I HPI   +  T++   
Sbjct: 109 TDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQ 168

Query: 158 FLIATVWTLGFAICSPLPVFHSL-VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLL 216
            +   +W L   +  P+ +  S  VE +E           L     P D +   F I + 
Sbjct: 169 AVNVAIWALASVVGVPVAIMGSAQVEDEEI--------ECLVEIPTPQDYWGPVFAICIF 220

Query: 217 LVQYILPLVCLTVSHTSVCRSI 238
           L  +I+P++ ++V ++ + R +
Sbjct: 221 LFSFIVPVLVISVCYSLMIRRL 242



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)

Query: 347 VHELRVKRSVTRIKKRSRSVFYRLTILILV----FAVSWMPLHLFHVVTDFNDNLISNRH 402
           +  LR  R ++  +++ R++  R+T L+LV    F   W P+ +F +         S   
Sbjct: 239 IRRLRGVRLLSGSREKDRNL-RRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETA 297

Query: 403 FKLVYCICHLLGMMSCCLNPILYGFLNNGIKA 434
             ++   C  LG ++ CLNPILY FL+   KA
Sbjct: 298 VAILR-FCTALGYVNSCLNPILYAFLDENFKA 328


>gi|161484640 neuromedin B receptor [Homo sapiens]
          Length = 390

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 51/208 (24%), Positives = 99/208 (47%), Gaps = 5/208 (2%)

Query: 47  LYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQ 106
           LY  +  +G +GN++++   +     ++  N  I NLA  D+L++L C P   +    D+
Sbjct: 49  LYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDE 108

Query: 107 WMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTL 166
           WMFGKV C ++P +Q  SV VS   L +++  RY  I +P+    +   G  L   V  +
Sbjct: 109 WMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTS---GALLRTCVKAM 165

Query: 167 GFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWP--SDSYRIAFTISLLLVQYILPL 224
           G  + S L      V  +    S+L +S +     +P   + +    ++ + LV +++PL
Sbjct: 166 GIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPL 225

Query: 225 VCLTVSHTSVCRSISCGLSNKENRLEEN 252
             +++ +  + +++     N      E+
Sbjct: 226 AIISIYYYHIAKTLIKSAHNLPGEYNEH 253



 Score = 32.3 bits (72), Expect = 0.89
 Identities = 21/87 (24%), Positives = 36/87 (41%), Gaps = 5/87 (5%)

Query: 361 KRSRSVFYRLTILILVFA----VSWMPLHLFHVVTDFNDNLIS-NRHFKLVYCICHLLGM 415
           K+      RL  ++LVF       W P H+ ++   FN N I  +    +V  +  +L  
Sbjct: 255 KKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSF 314

Query: 416 MSCCLNPILYGFLNNGIKADLVSLIHC 442
            + C+NP     L+   +    S + C
Sbjct: 315 GNSCVNPFALYLLSESFRRHFNSQLCC 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,078,219
Number of Sequences: 37866
Number of extensions: 688298
Number of successful extensions: 3586
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 469
Number of HSP's successfully gapped in prelim test: 173
Number of HSP's that attempted gapping in prelim test: 2386
Number of HSP's gapped (non-prelim): 1068
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.