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Search of human proteins with 54020718
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1
[Homo sapiens]
(494 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho... 994 0.0
gi|40316915 arginyl aminopeptidase [Homo sapiens] 456 e-128
gi|4505029 leukotriene A4 hydrolase [Homo sapiens] 244 2e-64
gi|94818891 type 1 tumor necrosis factor receptor shedding amino... 81 2e-15
gi|94818901 type 1 tumor necrosis factor receptor shedding amino... 81 2e-15
gi|157266300 membrane alanine aminopeptidase precursor [Homo sap... 76 6e-14
gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 72 9e-13
gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 72 9e-13
gi|194239713 laeverin [Homo sapiens] 70 4e-12
gi|24432058 aminopeptidase O [Homo sapiens] 69 7e-12
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens] 69 1e-11
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens] 69 1e-11
gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo ... 67 5e-11
gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens] 59 1e-08
gi|132814467 glutamyl aminopeptidase [Homo sapiens] 58 2e-08
gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens] 34 0.35
gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens] 34 0.35
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 31 3.0
gi|34304360 nephrocystin 3 [Homo sapiens] 30 3.9
gi|4504725 interferon regulatory factor 3 [Homo sapiens] 30 6.6
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti... 30 6.6
gi|239749706 PREDICTED: hypothetical protein XP_002347125 [Homo ... 29 8.6
gi|4507347 TBP-associated factor 2 [Homo sapiens] 29 8.6
gi|46409646 hypothetical protein LOC401563 [Homo sapiens] 29 8.6
>gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Homo
sapiens]
Length = 494
Score = 994 bits (2569), Expect = 0.0
Identities = 494/494 (100%), Positives = 494/494 (100%)
Query: 1 MSATRSAYMEEEGVFHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKL 60
MSATRSAYMEEEGVFHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKL
Sbjct: 1 MSATRSAYMEEEGVFHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKL 60
Query: 61 SGAVEQWLSAAERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDV 120
SGAVEQWLSAAERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDV
Sbjct: 61 SGAVEQWLSAAERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDV 120
Query: 121 IHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQM 180
IHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQM
Sbjct: 121 IHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQM 180
Query: 181 KLLGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVE 240
KLLGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVE
Sbjct: 181 KLLGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVE 240
Query: 241 KYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTR 300
KYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTR
Sbjct: 241 KYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTR 300
Query: 301 PVEALFQLWTAEPLDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYS 360
PVEALFQLWTAEPLDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYS
Sbjct: 301 PVEALFQLWTAEPLDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYS 360
Query: 361 SLLDSMNAEIRIRWLQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCTGALKSFAL 420
SLLDSMNAEIRIRWLQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCTGALKSFAL
Sbjct: 361 SLLDSMNAEIRIRWLQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCTGALKSFAL 420
Query: 421 EVFYQTQGRLHPNLRRAIQQILSQGLGSSTEPASEPSTELGKAEADTDSDAQALLLGDEA 480
EVFYQTQGRLHPNLRRAIQQILSQGLGSSTEPASEPSTELGKAEADTDSDAQALLLGDEA
Sbjct: 421 EVFYQTQGRLHPNLRRAIQQILSQGLGSSTEPASEPSTELGKAEADTDSDAQALLLGDEA 480
Query: 481 PSSAISLRDVNVSA 494
PSSAISLRDVNVSA
Sbjct: 481 PSSAISLRDVNVSA 494
>gi|40316915 arginyl aminopeptidase [Homo sapiens]
Length = 650
Score = 456 bits (1172), Expect = e-128
Identities = 217/431 (50%), Positives = 293/431 (67%), Gaps = 4/431 (0%)
Query: 15 FHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERL 74
F F M P+P+YL+AL GDL A++GPRSRVWAEPCL+ A + +G +E++L+ E+L
Sbjct: 218 FFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKL 277
Query: 75 YGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWFGNAVT 134
+GPY+WGRYD++F+PPSFP MENPCLTF+ +L D L +IHE++HSWFGN VT
Sbjct: 278 FGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVT 337
Query: 135 NATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGEDSPVSKLQV 194
NA W E WL+EG YAQRRI+T +GAA+TCLE A L + M + GE++P++KL+V
Sbjct: 338 NANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRV 397
Query: 195 KLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLLD 254
K+EPGV+P N YEKG+CFV YL+ L GD +FD FL+AYV ++KF S++A D LD
Sbjct: 398 KIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLD 457
Query: 255 SFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEPL 314
+L +FPELK++ VD G EF+RWLN G P PDLS G SL +P E L QLW AE L
Sbjct: 458 FYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEEL 517
Query: 315 DQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRIRW 374
D A A A IS W+T+Q FLD++L SPLP V L Y S+ ++ NAE+R+RW
Sbjct: 518 DMKAIEAVA--ISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRW 575
Query: 375 LQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCTGA--LKSFALEVFYQTQGRLHP 432
QIV++ND+ D +V+ FL +Q + YT+PLY + G+ ++ A E F T +LH
Sbjct: 576 GQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHS 635
Query: 433 NLRRAIQQILS 443
N+ +QQI++
Sbjct: 636 NVVNYVQQIVA 646
>gi|4505029 leukotriene A4 hydrolase [Homo sapiens]
Length = 611
Score = 244 bits (622), Expect = 2e-64
Identities = 142/420 (33%), Positives = 217/420 (51%), Gaps = 11/420 (2%)
Query: 14 VFHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAER 73
++ F + P+P YL+ALV G L+ IGPR+ VW+E + + + S E L AE
Sbjct: 189 IYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFS-ETESMLKIAED 247
Query: 74 LYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWFGNAV 133
L GPY+WG+YD++ LPPSFP MENPCLTF+ ++L D+ L + HE++HSW GN V
Sbjct: 248 LGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLV 307
Query: 134 TNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGEDSPVSKLQ 193
TN TW+ WL+EG Y +R I +G F L +K GE P +KL
Sbjct: 308 TNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLV 367
Query: 194 VKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLL 253
V L ++P + YEKG+ ++YL QL G P+ F FL+AYVEK+ + S+ D
Sbjct: 368 VDL-TDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWK 426
Query: 254 DSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEP 313
D S+F + VD +++ WL + G P +P+ +LT AL Q W
Sbjct: 427 DFLYSYF----KDKVDVLNQVDWNAWLYSPGLPPIKPNYDM--TLTNACIALSQRWITAK 480
Query: 314 LDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRIR 373
D S +A D+ + Q FL + L +PLP + + + Y+ + N+EIR R
Sbjct: 481 EDD-LNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAIN-NSEIRFR 538
Query: 374 WLQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLCT-GALKSFALEVFYQTQGRLHP 432
WL++ +++ + + + Q +T PL++DL A+ + + + +HP
Sbjct: 539 WLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHP 598
>gi|94818891 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform b [Homo sapiens]
Length = 941
Score = 80.9 bits (198), Expect = 2e-15
Identities = 75/272 (27%), Positives = 113/272 (41%), Gaps = 45/272 (16%)
Query: 16 HFHMEHPVPAYLVALVAGDL----KPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAA 71
HF + + YLVA + D K G + V+A P + A L AV
Sbjct: 235 HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYE 294
Query: 72 ERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEF---------LVIDVIH 122
+ PY + D+ +P F AMEN LT S L D + + V H
Sbjct: 295 DYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAH 353
Query: 123 EVAHSWFGNAVTNATWEEMWLSEGLA----------TYAQRRITTETYGAAFTCLETAFR 172
E+AH WFGN VT W ++WL+EG A T+ + ++ +G F +E
Sbjct: 354 ELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAME---- 409
Query: 173 LDALHRQMKLLGEDSPVSKLQVKLEPGVNPSHLMNLF---TYEKGYCFVYYLSQLCGDPQ 229
+DAL+ PVS P NP+ + +F +Y+KG C + L +
Sbjct: 410 VDALN-------SSHPVS------TPVENPAQIREMFDDVSYDKGACILNMLREYL-SAD 455
Query: 230 RFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFP 261
F + Y++K+ + + +DL DS S P
Sbjct: 456 AFKSGIVQYLQKHSYKNTKNEDLWDSMASICP 487
>gi|94818901 type 1 tumor necrosis factor receptor shedding
aminopeptidase regulator isoform a [Homo sapiens]
Length = 948
Score = 80.9 bits (198), Expect = 2e-15
Identities = 75/272 (27%), Positives = 113/272 (41%), Gaps = 45/272 (16%)
Query: 16 HFHMEHPVPAYLVALVAGDL----KPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAA 71
HF + + YLVA + D K G + V+A P + A L AV
Sbjct: 235 HFDVTVKMSTYLVAFIISDFESVSKITKSGVKVSVYAVPDKINQADYALDAAVTLLEFYE 294
Query: 72 ERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEF---------LVIDVIH 122
+ PY + D+ +P F AMEN LT S L D + + V H
Sbjct: 295 DYFSIPYPLPKQDLAAIP-DFQSGAMENWGLTTYRESALLFDAEKSSASSKLGITMTVAH 353
Query: 123 EVAHSWFGNAVTNATWEEMWLSEGLA----------TYAQRRITTETYGAAFTCLETAFR 172
E+AH WFGN VT W ++WL+EG A T+ + ++ +G F +E
Sbjct: 354 ELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVSVTHPELKVGDYFFGKCFDAME---- 409
Query: 173 LDALHRQMKLLGEDSPVSKLQVKLEPGVNPSHLMNLF---TYEKGYCFVYYLSQLCGDPQ 229
+DAL+ PVS P NP+ + +F +Y+KG C + L +
Sbjct: 410 VDALN-------SSHPVS------TPVENPAQIREMFDDVSYDKGACILNMLREYL-SAD 455
Query: 230 RFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFP 261
F + Y++K+ + + +DL DS S P
Sbjct: 456 AFKSGIVQYLQKHSYKNTKNEDLWDSMASICP 487
>gi|157266300 membrane alanine aminopeptidase precursor [Homo
sapiens]
Length = 967
Score = 76.3 bits (186), Expect = 6e-14
Identities = 80/323 (24%), Positives = 128/323 (39%), Gaps = 42/323 (13%)
Query: 14 VFHFHMEHPVPAYLVALVAGDL----KPADIGPRSRVWAEPCLLPTATS----KLSGAVE 65
V FH + YL+A + + K A G R+WA P + ++G +
Sbjct: 266 VTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPIL 325
Query: 66 QWLSAAERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFI---------ISSILESDEFL 116
+ A PY + D + LP F AMEN L +SS + E +
Sbjct: 326 NFF--AGHYDTPYPLPKSDQIGLP-DFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERV 382
Query: 117 VIDVIHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDAL 176
V + HE+AH WFGN VT W ++WL+EG A+Y + Y L+ L+ +
Sbjct: 383 VTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVE--YLGADYAEPTWNLKDLMVLNDV 440
Query: 177 HRQMKL--LGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDF 234
+R M + L P+S ++ S L + +Y KG + LS + F
Sbjct: 441 YRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSE-DVFKQG 499
Query: 235 LRAYVEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLE--FERWLNATGPPLAEPDL 292
L +Y+ + + + + +L D + +S+ + RW G P+ D
Sbjct: 500 LASYLHTFAYQNTIYLNLWDHLQE---AVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDT 556
Query: 293 SQG------------SSLTRPVE 303
S G S++TRP E
Sbjct: 557 STGTLSQEHFLLDPDSNVTRPSE 579
>gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 72.4 bits (176), Expect = 9e-13
Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 27/257 (10%)
Query: 16 HFHMEHPVPAYLVALVAGDLKP----ADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAA 71
HF + YLVA + D G + ++A P L +++ L
Sbjct: 252 HFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKL-LDFY 310
Query: 72 ERLYGPYM-WGRYDIVFLPPSFPIVAMEN-PCLTFIISSIL-------ESDEFLVIDVI- 121
E+ + Y + D++ +P P AMEN +T+ +S+L SD+ V VI
Sbjct: 311 EKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIA 369
Query: 122 HEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMK 181
HE+AH WFGN VT W ++WL EG A Y + TY E F L+ +
Sbjct: 370 HELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYP------ELQFDDYFLNVCFE 423
Query: 182 LLGEDSPVSKLQVKLEPGVNPSHLMNLF---TYEKGYCFVYYLSQLCGDPQRFDDFLRAY 238
++ +DS S + +P P+ + +F +Y KG C + L G+ ++F + Y
Sbjct: 424 VITKDSLNSSRPIS-KPAETPTQIQEMFDEVSYNKGACILNMLKDFLGE-EKFQKGIIQY 481
Query: 239 VEKYKFTSVVAQDLLDS 255
++K+ + + DL S
Sbjct: 482 LKKFSYRNAKNDDLWSS 498
>gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens]
Length = 960
Score = 72.4 bits (176), Expect = 9e-13
Identities = 69/257 (26%), Positives = 113/257 (43%), Gaps = 27/257 (10%)
Query: 16 HFHMEHPVPAYLVALVAGDLKP----ADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAA 71
HF + YLVA + D G + ++A P L +++ L
Sbjct: 252 HFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKL-LDFY 310
Query: 72 ERLYGPYM-WGRYDIVFLPPSFPIVAMEN-PCLTFIISSIL-------ESDEFLVIDVI- 121
E+ + Y + D++ +P P AMEN +T+ +S+L SD+ V VI
Sbjct: 311 EKYFDIYYPLSKLDLIAIPDFAP-GAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIA 369
Query: 122 HEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMK 181
HE+AH WFGN VT W ++WL EG A Y + TY E F L+ +
Sbjct: 370 HELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYP------ELQFDDYFLNVCFE 423
Query: 182 LLGEDSPVSKLQVKLEPGVNPSHLMNLF---TYEKGYCFVYYLSQLCGDPQRFDDFLRAY 238
++ +DS S + +P P+ + +F +Y KG C + L G+ ++F + Y
Sbjct: 424 VITKDSLNSSRPIS-KPAETPTQIQEMFDEVSYNKGACILNMLKDFLGE-EKFQKGIIQY 481
Query: 239 VEKYKFTSVVAQDLLDS 255
++K+ + + DL S
Sbjct: 482 LKKFSYRNAKNDDLWSS 498
>gi|194239713 laeverin [Homo sapiens]
Length = 990
Score = 70.1 bits (170), Expect = 4e-12
Identities = 74/300 (24%), Positives = 120/300 (40%), Gaps = 31/300 (10%)
Query: 23 VPAYLVALVAGD---LKPADIGPRSRVWAEPCLLPTATS----KLSGAVEQWLSAAERLY 75
+P YLVA V D + + G R+WA + ++ ++G + +L E L+
Sbjct: 303 MPTYLVAFVICDYDHVNRTERGKEIRIWARKDAIANGSADFALNITGPIFSFL---EDLF 359
Query: 76 G-PYMWGRYDIVFLPPSFPIVAMENPCLTFIISS---------ILESDEFLVIDVIHEVA 125
Y + DI+ LP SF AMEN L S + E + V HE+
Sbjct: 360 NISYSLPKTDIIALP-SFDNHAMENWGLMIFDESGLLLEPKDQLTEKKTLISYVVSHEIG 418
Query: 126 HSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGE 185
H WFGN VT W +WL+EG A+Y + + Y F + LH +L E
Sbjct: 419 HQWFGNLVTMNWWNNIWLNEGFASYFEFEVI--NYFNPKLPRNEIFFSNILH---NILRE 473
Query: 186 DSPVSKLQVKLE----PGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEK 241
D + V ++ L ++FTY KG LS + F L++Y++
Sbjct: 474 DHALVTRAVAMKVENFKTSEIQELFDIFTYSKGASMARMLSCFLNE-HLFVSALKSYLKT 532
Query: 242 YKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQGSSLTRP 301
+ +++ DL F + + + W + +G P+ ++S G P
Sbjct: 533 FSYSNAEQDDLWRHFQMAIDDQSTVILPATIKNIMDSWTHQSGFPVITLNVSTGVMKQEP 592
>gi|24432058 aminopeptidase O [Homo sapiens]
Length = 720
Score = 69.3 bits (168), Expect = 7e-12
Identities = 64/257 (24%), Positives = 110/257 (42%), Gaps = 19/257 (7%)
Query: 196 LEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLLDS 255
++ G+NP + Y KGY + +L++ GD F FLR +V + +++QD L
Sbjct: 472 IKHGLNPEKIFMQVHYLKGYFLLRFLAKRLGDETYFS-FLRKFVHTFHGQLILSQDFLQM 530
Query: 256 FLSFFPELKEQSVDCRAGLEFERWLNATGPPLA---EPDLSQGSSLTRPVEALFQLWTA- 311
L PE E+ ++ ++ WL ++G P E L R V A W
Sbjct: 531 LLENIPE--EKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGV 588
Query: 312 --EPLDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAE 369
P + + K Q L L+ LL+ L + SL + Y L +AE
Sbjct: 589 NRRPRKRKRREKEEV-FEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYH--LQDQDAE 645
Query: 370 IRIRWLQIVVRNDYYPDLHRVRRFL-ESQMSRMYTIPLYEDLCT---GALKSFALEVFYQ 425
+R RW +++V++ + V RFL E Q +Y LY +L + A F +
Sbjct: 646 VRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVY---LYGELMVSEDARQQQLARRCFER 702
Query: 426 TQGRLHPNLRRAIQQIL 442
T+ ++ + + + ++L
Sbjct: 703 TKEQMDRSSAQVVAEML 719
Score = 38.9 bits (89), Expect = 0.011
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 18 HMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGP 77
HME+P + ++ P RV+A CL L + LSAA + G
Sbjct: 380 HMEYPCRFQNASATTQEIIP------HRVFAPVCLTGACQETLLRLIPPCLSAAHSVLGA 433
Query: 78 YMWGRYDIVFLPPSFPIVAMENP 100
+ + R D++ +P +FP + M P
Sbjct: 434 HPFSRLDVLIVPANFPSLGMARP 456
>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]
Length = 1025
Score = 68.6 bits (166), Expect = 1e-11
Identities = 76/284 (26%), Positives = 120/284 (42%), Gaps = 44/284 (15%)
Query: 26 YLVALVAGDLK--PADI-GPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGR 82
YLVA + G++K D+ G ++A P + L V+ Y +
Sbjct: 357 YLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKK 416
Query: 83 YDIVFLPPSFPIVAMEN-PCLTFIISSILE-------SDEFLVIDVI-HEVAHSWFGNAV 133
D+V +P F AMEN LTF ++L +D LV +I HE+AH WFGN V
Sbjct: 417 LDLVAIP-DFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLV 475
Query: 134 TNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFR--------LDALHRQMK--LL 183
T W ++WL+EG AT+ + + LE F+ LDA + MK L
Sbjct: 476 TMKWWNDLWLNEGFATFME-----------YFSLEKIFKELSSYEDFLDARFKTMKKDSL 524
Query: 184 GEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYK 243
P+S ++ + + +Y KG + L + F + Y+ +
Sbjct: 525 NSSHPISS---SVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSE-DVFQHAVVLYLHNHS 580
Query: 244 FTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPL 287
+ S+ + DL DS F E+ Q++D + + + W G PL
Sbjct: 581 YASIQSDDLWDS----FNEVTNQTLDVKRMM--KTWTLQKGFPL 618
>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]
Length = 1011
Score = 68.6 bits (166), Expect = 1e-11
Identities = 76/284 (26%), Positives = 120/284 (42%), Gaps = 44/284 (15%)
Query: 26 YLVALVAGDLK--PADI-GPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGR 82
YLVA + G++K D+ G ++A P + L V+ Y +
Sbjct: 343 YLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKK 402
Query: 83 YDIVFLPPSFPIVAMEN-PCLTFIISSILE-------SDEFLVIDVI-HEVAHSWFGNAV 133
D+V +P F AMEN LTF ++L +D LV +I HE+AH WFGN V
Sbjct: 403 LDLVAIP-DFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLV 461
Query: 134 TNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFR--------LDALHRQMK--LL 183
T W ++WL+EG AT+ + + LE F+ LDA + MK L
Sbjct: 462 TMKWWNDLWLNEGFATFME-----------YFSLEKIFKELSSYEDFLDARFKTMKKDSL 510
Query: 184 GEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYK 243
P+S ++ + + +Y KG + L + F + Y+ +
Sbjct: 511 NSSHPISS---SVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSE-DVFQHAVVLYLHNHS 566
Query: 244 FTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPL 287
+ S+ + DL DS F E+ Q++D + + + W G PL
Sbjct: 567 YASIQSDDLWDS----FNEVTNQTLDVKRMM--KTWTLQKGFPL 604
>gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo
sapiens]
Length = 1024
Score = 66.6 bits (161), Expect = 5e-11
Identities = 51/187 (27%), Positives = 85/187 (45%), Gaps = 17/187 (9%)
Query: 77 PYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFL-----VIDV----IHEVAHS 127
PY + D++ +P P AMEN L+ + + D + ++DV +HE+ H
Sbjct: 387 PYSLPKLDLLAVP-KHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQ 445
Query: 128 WFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKL--LGE 185
WFG+ VT WE++WL EG A Y + + T+ + + F D LH M L L
Sbjct: 446 WFGDLVTPVWWEDVWLKEGFAHYFE-FVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLAS 504
Query: 186 DSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFT 245
PVS+ ++ + + + Y+KG + L+ G F L+ Y+ +K+
Sbjct: 505 SHPVSQ---EVLQATDIDRVFDWIAYKKGAALIRMLANFMGH-SVFQRGLQDYLTIHKYG 560
Query: 246 SVVAQDL 252
+ DL
Sbjct: 561 NAARNDL 567
>gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens]
Length = 919
Score = 58.5 bits (140), Expect = 1e-08
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 34/198 (17%)
Query: 77 PYMWGRYDIVFLPPSFPIVAMEN-PCLTFIISSIL--------ESDEFLVIDVIHEVAHS 127
PY + D++ + F AMEN +T+ +++L S +++ + V HE+AH
Sbjct: 299 PYPLPKIDLIAIA-DFAAGAMENWGLVTYRETALLIDPKNSCSSSRQWVALVVGHELAHQ 357
Query: 128 WFGNAVTNATWEEMWLSEGLAT----------YAQRRITTETYGAAFTCLETAFRLDALH 177
WFGN VT W +WL+EG A+ + + I T+ A +T + LD H
Sbjct: 358 WFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQELDALDNSH 417
Query: 178 RQMKLLGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRA 237
+G S V + + + +Y KG + L GD + F +
Sbjct: 418 PIEVSVGHPSEVDE-------------IFDAISYSKGASVIRMLHDYIGD-KDFKKGMNM 463
Query: 238 YVEKYKFTSVVAQDLLDS 255
Y+ K++ + +DL +S
Sbjct: 464 YLTKFQQKNAATEDLWES 481
>gi|132814467 glutamyl aminopeptidase [Homo sapiens]
Length = 957
Score = 57.8 bits (138), Expect = 2e-08
Identities = 45/174 (25%), Positives = 74/174 (42%), Gaps = 19/174 (10%)
Query: 90 PSFPIVAMEN-PCLTFIISSIL--------ESDEFLVIDVIHEVAHSWFGNAVTNATWEE 140
P F AMEN +T+ +++L + + + V HE+ H WFGN VT WE+
Sbjct: 352 PDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWED 411
Query: 141 MWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMKLLGEDSPVSKLQVKLEPGV 200
+WL+EG A++ E G + R L + + ED + +
Sbjct: 412 LWLNEGFASF------FEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVT 465
Query: 201 NPSHLMNLF---TYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQD 251
P + ++F +Y KG + L P+ F + Y+EKY+F + D
Sbjct: 466 TPDEITSVFDGISYSKGSSILRMLEDWI-KPENFQKGCQMYLEKYQFKNAKTSD 518
>gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]
Length = 1726
Score = 33.9 bits (76), Expect = 0.35
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 276 FERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEPLDQAAASASAIDISKWRTFQTA 335
F RWL+ T P E ++S + PVEA+F T + + +A + A + + A
Sbjct: 1289 FSRWLSCTATPQIEEEVSL-TQKNSPVEAVFSYLTGKRISEACSLA-----QQSGDHRLA 1342
Query: 336 LFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRIR 373
L L + + + + + M L + DS + R+R
Sbjct: 1343 LLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR 1380
>gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]
Length = 1800
Score = 33.9 bits (76), Expect = 0.35
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 276 FERWLNATGPPLAEPDLSQGSSLTRPVEALFQLWTAEPLDQAAASASAIDISKWRTFQTA 335
F RWL+ T P E ++S + PVEA+F T + + +A + A + + A
Sbjct: 1289 FSRWLSCTATPQIEEEVSL-TQKNSPVEAVFSYLTGKRISEACSLA-----QQSGDHRLA 1342
Query: 336 LFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAEIRIR 373
L L + + + + + M L + DS + R+R
Sbjct: 1343 LLLSQFVGSQSVRELLTMQLVDWHQLQADSFIQDERLR 1380
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 30.8 bits (68), Expect = 3.0
Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 4/59 (6%)
Query: 255 SFLSFFPE---LKEQSVDCRAGLEFE-RWLNATGPPLAEPDLSQGSSLTRPVEALFQLW 309
S L FP LKEQ R L++E W+ T EP + +S TR V F LW
Sbjct: 413 SALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFFGLW 471
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 30.4 bits (67), Expect = 3.9
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 18/99 (18%)
Query: 394 LESQMSR-MYTIPLYEDLCTGALKSFALEVFYQTQGRLHPNLRRAIQQ--ILSQGLGSST 450
L SQM + + +PLYE AL+++ + GR+HP + ++ +LS G
Sbjct: 1228 LYSQMKKHVEALPLYER---------ALKIYEDSLGRMHPRVGETLKNLAVLSYEGGD-- 1276
Query: 451 EPASEPSTELGKAEADTDSDAQALLLGDEAPSSAISLRD 489
E + EL K + +A+ LLG +APS S D
Sbjct: 1277 ---FEKAAELYKRAMEI-KEAETSLLGGKAPSRHSSSGD 1311
>gi|4504725 interferon regulatory factor 3 [Homo sapiens]
Length = 427
Score = 29.6 bits (65), Expect = 6.6
Identities = 14/47 (29%), Positives = 25/47 (53%)
Query: 432 PNLRRAIQQILSQGLGSSTEPASEPSTELGKAEADTDSDAQALLLGD 478
P+ I + ++ G+G ++P + P T G + +DT D LLG+
Sbjct: 100 PHDPHKIYEFVNSGVGDFSQPDTSPDTNGGGSTSDTQEDILDELLGN 146
>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
exchange factor 1 [Homo sapiens]
Length = 1859
Score = 29.6 bits (65), Expect = 6.6
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 233 DFLRAYVEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEF-ERWLNATGPPLAEPD 291
D L ++V + F + + L +L F E V R F ERW+N G P A D
Sbjct: 762 DLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSD 821
>gi|239749706 PREDICTED: hypothetical protein XP_002347125 [Homo
sapiens]
Length = 215
Score = 29.3 bits (64), Expect = 8.6
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
Query: 42 PRSRVWA----EPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGRYDIVFLPPSFPIVAM 97
PR RV EP +LP ++L+G++ LS + L P++ + PPS P + +
Sbjct: 95 PRLRVTRPLVPEPAILPVCAARLAGSLATDLSRSHSLLPPWVDLKEP---PPPSAPSLLL 151
Query: 98 ENP 100
E+P
Sbjct: 152 EDP 154
>gi|4507347 TBP-associated factor 2 [Homo sapiens]
Length = 1199
Score = 29.3 bits (64), Expect = 8.6
Identities = 33/157 (21%), Positives = 65/157 (41%), Gaps = 13/157 (8%)
Query: 15 FHFHMEHPVPAYLVALVAGDLKPADIGPRSRV--WAEPCLLPTATSKLSGAVEQWLSAAE 72
FH+ + P A ++L G + V + P LLP S E + E
Sbjct: 234 FHYMLTIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEE 293
Query: 73 RLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVID--------VIHEV 124
L Y + + VF+ ++ VA ++ +++L S ++ID + +
Sbjct: 294 ILTCRYPYSCFKTVFIDEAYVEVAAY-ASMSIFSTNLLHSA--MIIDETPLTRRCLAQSL 350
Query: 125 AHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYG 161
A +FG ++ +W + W+ +G++ Y +T+G
Sbjct: 351 AQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFG 387
>gi|46409646 hypothetical protein LOC401563 [Homo sapiens]
Length = 190
Score = 29.3 bits (64), Expect = 8.6
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
Query: 42 PRSRVWA----EPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGRYDIVFLPPSFPIVAM 97
PR RV EP +LP ++L+G++ LS + L P++ + PPS P + +
Sbjct: 70 PRLRVTRPLVPEPAILPVCAARLAGSLATDLSRSHSLLPPWVDLKEP---PPPSAPSLLL 126
Query: 98 ENP 100
E+P
Sbjct: 127 EDP 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,768,914
Number of Sequences: 37866
Number of extensions: 814064
Number of successful extensions: 2008
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1980
Number of HSP's gapped (non-prelim): 28
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.