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Search of human proteins with 53729346
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
(747 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens] 1500 0.0
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens] 1450 0.0
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ... 1246 0.0
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens] 350 3e-96
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens] 329 7e-90
gi|53829376 plakophilin 4 isoform b [Homo sapiens] 260 3e-69
gi|53829374 plakophilin 4 isoform a [Homo sapiens] 260 3e-69
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 251 2e-66
gi|6005830 plakophilin 3 [Homo sapiens] 247 3e-65
gi|4502247 armadillo repeat protein [Homo sapiens] 234 2e-61
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] 218 2e-56
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] 218 2e-56
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] 218 2e-56
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] 218 2e-56
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens] 218 2e-56
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens] 218 2e-56
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens] 218 2e-56
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens] 218 2e-56
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens] 218 2e-56
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens] 218 2e-56
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens] 216 8e-56
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens] 216 8e-56
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens] 216 8e-56
gi|189409124 armadillo repeat containing 3 [Homo sapiens] 42 0.003
gi|189011568 adenomatous polyposis coli [Homo sapiens] 41 0.005
gi|189011566 adenomatous polyposis coli [Homo sapiens] 41 0.005
gi|53759122 adenomatous polyposis coli [Homo sapiens] 41 0.005
gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2 [... 39 0.018
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD... 38 0.039
gi|148233338 catenin (cadherin-associated protein), beta 1, 88kD... 38 0.039
>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
Length = 747
Score = 1500 bits (3884), Expect = 0.0
Identities = 747/747 (100%), Positives = 747/747 (100%)
Query: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS
Sbjct: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
Query: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY
Sbjct: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
Query: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT
Sbjct: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
Query: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI
Sbjct: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
Query: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN
Sbjct: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
Query: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST
Sbjct: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
Query: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELL 420
DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELL
Sbjct: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELL 420
Query: 421 ALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH 480
ALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH
Sbjct: 421 ALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH 480
Query: 481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS 540
NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS
Sbjct: 481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS 540
Query: 541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI 600
GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI
Sbjct: 541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI 600
Query: 601 ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS 660
ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS
Sbjct: 601 ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS 660
Query: 661 ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV 720
ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV
Sbjct: 661 ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV 720
Query: 721 LRQQGFDRNMLGTLAGANSLRNFTSRF 747
LRQQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 721 LRQQGFDRNMLGTLAGANSLRNFTSRF 747
>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
Length = 726
Score = 1450 bits (3754), Expect = 0.0
Identities = 726/747 (97%), Positives = 726/747 (97%), Gaps = 21/747 (2%)
Query: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS
Sbjct: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
Query: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY
Sbjct: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
Query: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT
Sbjct: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
Query: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI
Sbjct: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
Query: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN
Sbjct: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
Query: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST
Sbjct: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
Query: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELL 420
DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLR
Sbjct: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLR--------- 411
Query: 421 ALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH 480
NLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH
Sbjct: 412 ------------NLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH 459
Query: 481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS 540
NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS
Sbjct: 460 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS 519
Query: 541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI 600
GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI
Sbjct: 520 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI 579
Query: 601 ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS 660
ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS
Sbjct: 580 ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS 639
Query: 661 ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV 720
ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV
Sbjct: 640 ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV 699
Query: 721 LRQQGFDRNMLGTLAGANSLRNFTSRF 747
LRQQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 700 LRQQGFDRNMLGTLAGANSLRNFTSRF 726
>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
sapiens]
Length = 625
Score = 1246 bits (3225), Expect = 0.0
Identities = 625/646 (96%), Positives = 625/646 (96%), Gaps = 21/646 (3%)
Query: 102 PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 161
PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC
Sbjct: 1 PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 60
Query: 162 DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 221
DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN
Sbjct: 61 DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 120
Query: 222 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 281
KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ
Sbjct: 121 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 180
Query: 282 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 341
QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT
Sbjct: 181 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 240
Query: 342 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 401
GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE
Sbjct: 241 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
Query: 402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNC 461
VFFNATGCLR NLSSADAGRQTMRNYSGLIDSLMAYVQNC
Sbjct: 301 VFFNATGCLR---------------------NLSSADAGRQTMRNYSGLIDSLMAYVQNC 339
Query: 462 VAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKM 521
VAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKM
Sbjct: 340 VAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKM 399
Query: 522 MNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGL 581
MNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGL
Sbjct: 400 MNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGL 459
Query: 582 MSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVT 641
MSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVT
Sbjct: 460 MSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVT 519
Query: 642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA 701
RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA
Sbjct: 520 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA 579
Query: 702 EAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF 747
EAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 580 EAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLRNFTSRF 625
>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
Length = 837
Score = 350 bits (898), Expect = 3e-96
Identities = 198/503 (39%), Positives = 300/503 (59%), Gaps = 31/503 (6%)
Query: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290
S++ + D+E +T+ +AV L + I A +IQH CFQ A+++V QL GI
Sbjct: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
Query: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350
KL+ LL+ N++VQ+A GALRNLVF NKLE NG+ + +L++T + E +KQ+
Sbjct: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
Query: 351 TGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCL 410
TGLLWNLSS D+LK +I +AL L + +IIPFSGW +G+ + ++D ++F+N TGCL
Sbjct: 459 TGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCL 518
Query: 411 RKRLGMRELLALVPQRATSSRVNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDD 469
R N+SSA A GR+ MR GLIDSL+ YV+ +A + DD
Sbjct: 519 R---------------------NMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDD 557
Query: 470 KSVENCMCVLHNLSYRLDAEVPTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYD 527
K+ ENC+C+LHNLSY+L+AE+P +Y Q Y RN T+ + S GCF ++S K+ D
Sbjct: 558 KATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQD 617
Query: 528 CPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMS 587
P+PEE++NPKG WL+HS IR YL+L+ KS ++ T EA GALQNLTA G M + ++
Sbjct: 618 VPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVA 677
Query: 588 QLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSH 647
Q + KE GL ++L G+ V ++ SLL N+SR+ L + + P++ ++
Sbjct: 678 QTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDT 737
Query: 648 TGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAAR 705
+T + +SACYT+ N++ + Q A+ ++ + I+ + AS KA++AA
Sbjct: 738 VPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAAS 797
Query: 706 LLLSDMWSSKELQGVLRQQGFDR 728
+LL +W+ EL ++ F +
Sbjct: 798 VLLYSLWAHTELHHAYKKAQFKK 820
Score = 39.7 bits (91), Expect = 0.010
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)
Query: 6 LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57
++T L + D+S+LALPS+ K+K G+SGR R+QEQV T+ R+ S
Sbjct: 13 IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
Query: 58 QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108
+ L ++ Y + +++ G + Y +AG G WG GT
Sbjct: 73 GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
Query: 109 KREPDNRRFSSYSQMENWSRHYP 131
++SS +E S +P
Sbjct: 128 ------AQYSSQKSVEERSLRHP 144
>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
Length = 881
Score = 329 bits (843), Expect = 7e-90
Identities = 198/547 (36%), Positives = 300/547 (54%), Gaps = 75/547 (13%)
Query: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290
S++ + D+E +T+ +AV L + I A +IQH CFQ A+++V QL GI
Sbjct: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
Query: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350
KL+ LL+ N++VQ+A GALRNLVF NKLE NG+ + +L++T + E +KQ+
Sbjct: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
Query: 351 T--------------------------------------------GLLWNLSSTDELKEE 366
T GLLWNLSS D+LK
Sbjct: 459 TDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNL 518
Query: 367 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQR 426
+I +AL L + +IIPFSGW +G+ + ++D ++F+N TGCLR
Sbjct: 519 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLR--------------- 563
Query: 427 ATSSRVNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYR 485
N+SSA A GR+ MR GLIDSL+ YV+ +A + DDK+ ENC+C+LHNLSY+
Sbjct: 564 ------NMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQ 617
Query: 486 LDAEVPTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWL 543
L+AE+P +Y Q Y RN T+ + S GCF ++S K+ D P+PEE++NPKG WL
Sbjct: 618 LEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWL 677
Query: 544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL 603
+HS IR YL+L+ KS ++ T EA GALQNLTA G M + ++Q + KE GL ++
Sbjct: 678 WHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKM 737
Query: 604 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACY 663
L G+ V ++ SLL N+SR+ L + + P++ ++ +T + +SACY
Sbjct: 738 LHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACY 797
Query: 664 TVRNLMASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVL 721
T+ N++ + Q A+ ++ + I+ + AS KA++AA +LL +W+ EL
Sbjct: 798 TLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAY 857
Query: 722 RQQGFDR 728
++ F +
Sbjct: 858 KKAQFKK 864
Score = 39.7 bits (91), Expect = 0.010
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)
Query: 6 LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57
++T L + D+S+LALPS+ K+K G+SGR R+QEQV T+ R+ S
Sbjct: 13 IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
Query: 58 QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108
+ L ++ Y + +++ G + Y +AG G WG GT
Sbjct: 73 GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
Query: 109 KREPDNRRFSSYSQMENWSRHYP 131
++SS +E S +P
Sbjct: 128 ------AQYSSQKSVEERSLRHP 144
>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
Length = 1149
Score = 260 bits (665), Expect = 3e-69
Identities = 168/503 (33%), Positives = 262/503 (52%), Gaps = 43/503 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L Q QA A Y+QH CF D K +V +LGGI LVDLL VQ+
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
Query: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
A GALRNLVF +T NK+ + GI + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 590 ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
Query: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRKRLGMRELLAL 422
+I DAL L + VI+P SGW + + + ++ V N TGCLR
Sbjct: 650 MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLR----------- 698
Query: 423 VPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN 481
NLSSA + R+ MR+ GL+DSL+ + CV S D K+VENC+C L N
Sbjct: 699 ----------NLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRN 748
Query: 482 LSYRLDAEVPTRYRQLEYN------ARNAYTEKSSTGCFSNKSDKMMNNNYD------CP 529
LSYRL+ EVP + R L N + + ++ S C+ K K + P
Sbjct: 749 LSYRLELEVP-QARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGP 807
Query: 530 LPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQL 589
+P +PKG L+H ++ YL L+ +S ATLE AG+LQNL+A ++ +
Sbjct: 808 IPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAA 867
Query: 590 IGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTG 649
+ KEKGLP + LL+ N VV S A+ L NM+ ++G ++ L G
Sbjct: 868 V-RKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNG 926
Query: 650 NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARL 706
+ S++ +++ C + + + + AK S + ++N+ + +S K +AA
Sbjct: 927 PSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQ 986
Query: 707 LLSDMWSSKELQGVLRQQGFDRN 729
+L+ +W ++L+ + ++ G+++N
Sbjct: 987 VLNTLWQYRDLRSIYKKDGWNQN 1009
>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
Length = 1192
Score = 260 bits (665), Expect = 3e-69
Identities = 168/503 (33%), Positives = 262/503 (52%), Gaps = 43/503 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L Q QA A Y+QH CF D K +V +LGGI LVDLL VQ+
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
Query: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
A GALRNLVF +T NK+ + GI + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 590 ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
Query: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRKRLGMRELLAL 422
+I DAL L + VI+P SGW + + + ++ V N TGCLR
Sbjct: 650 MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLR----------- 698
Query: 423 VPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN 481
NLSSA + R+ MR+ GL+DSL+ + CV S D K+VENC+C L N
Sbjct: 699 ----------NLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRN 748
Query: 482 LSYRLDAEVPTRYRQLEYN------ARNAYTEKSSTGCFSNKSDKMMNNNYD------CP 529
LSYRL+ EVP + R L N + + ++ S C+ K K + P
Sbjct: 749 LSYRLELEVP-QARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGP 807
Query: 530 LPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQL 589
+P +PKG L+H ++ YL L+ +S ATLE AG+LQNL+A ++ +
Sbjct: 808 IPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAA 867
Query: 590 IGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTG 649
+ KEKGLP + LL+ N VV S A+ L NM+ ++G ++ L G
Sbjct: 868 V-RKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNG 926
Query: 650 NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARL 706
+ S++ +++ C + + + + AK S + ++N+ + +S K +AA
Sbjct: 927 PSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQ 986
Query: 707 LLSDMWSSKELQGVLRQQGFDRN 729
+L+ +W ++L+ + ++ G+++N
Sbjct: 987 VLNTLWQYRDLRSIYKKDGWNQN 1009
>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
plakophilin-related arm-repeat protein) [Homo sapiens]
Length = 1225
Score = 251 bits (641), Expect = 2e-66
Identities = 170/508 (33%), Positives = 261/508 (51%), Gaps = 52/508 (10%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ +Q L Q Q+ A Y+QH CF D K ++ + GGI LVDLL V ++
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611
Query: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
A GALRNLV+ NK+ + GI V LLR+T + EI++ +TG+LWNLSS D LK
Sbjct: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671
Query: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREVV--DPEVFFNATGCLRKRLGMRELLAL 422
+I DAL VL + VIIP SGW + R++ +V NATGCLR
Sbjct: 672 MPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLR----------- 720
Query: 423 VPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN 481
N+SSA + R+ MR GL D+L+ +Q+ + +S D K+VENC+C+L N
Sbjct: 721 ----------NVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRN 770
Query: 482 LSYRLDAEVPTRYRQ----------LEYNARNAYTEKSSTGCFSNKSDKMMN-NNYD--C 528
LSYRL AE E N ++A S+GC+ K K + + +D
Sbjct: 771 LSYRLAAETSQGQHMGTDELDGLLCGEANGKDA----ESSGCWGKKKKKKKSQDQWDGVG 826
Query: 529 PLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQ 588
PLP+ PKG L+H ++ YL L+ + TLE AGALQNL A S +
Sbjct: 827 PLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRA 886
Query: 589 LIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLL---- 644
+ KEKGLP + LL+ N VV + A+ L NM+ ++G ++ L
Sbjct: 887 AV-RKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGN 945
Query: 645 -TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA---SPKA 700
+++T + + S+D +++ C T+ ++ + AK + + ++ + +S SPK
Sbjct: 946 NSNNTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKV 1005
Query: 701 AEAARLLLSDMWSSKELQGVLRQQGFDR 728
+AA +L+ MW ++L+ + ++ G+ +
Sbjct: 1006 VKAASQVLNSMWQYRDLRSLYKKDGWSQ 1033
>gi|6005830 plakophilin 3 [Homo sapiens]
Length = 797
Score = 247 bits (630), Expect = 3e-65
Identities = 172/520 (33%), Positives = 265/520 (50%), Gaps = 50/520 (9%)
Query: 225 SFGHSRASSKICS--EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQ 282
S+G R ++ S +DI+ +P AV+YL + D Q +GA YIQH C+ D +AK+Q
Sbjct: 302 SYGSHRTLQRLSSGFDDID-----LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQ 356
Query: 283 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 342
L + +LV L NQ VQ+ A GA+RNL++ + NKL +NGI E + LR
Sbjct: 357 ARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQD 416
Query: 343 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 402
+ E++K +TG+LWNLSS+D LK+ L D L L D V+ P SG G + + + E+
Sbjct: 417 D-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSG-AGGPPLIQQNASEAEI 474
Query: 403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQNC 461
F+NATG LR NLSSA A RQ MR GL+D+L+ + +
Sbjct: 475 FYNATGFLR---------------------NLSSASQATRQKMRECHGLVDALVTSINHA 513
Query: 462 VAASRCDDKSVENCMCVLHNLSYRL-DAEVPTRYRQLEYNARN---AYTEKSSTGCFSNK 517
+ A +C+DKSVEN +CVL NLSYRL D P+ ++LE R GCF+ +
Sbjct: 514 LDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQ 573
Query: 518 SDKMMNNNYDCPL-------PEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA-TLEACA 569
S ++ + PL E +PKG WL+ + Y L+ + + + T EA A
Sbjct: 574 SRRLR----ELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAA 629
Query: 570 GALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLH 629
GALQN+TA + +S+L +E+ L + +++ + +RS L+ N+SR+
Sbjct: 630 GALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNK 689
Query: 630 RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNII 689
M +V + L G S ++L + + NL+ + P A+ L +I
Sbjct: 690 DEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLI 749
Query: 690 NLCRSSASP---KAAEAARLLLSDMWSSKELQGVLRQQGF 726
+ + SP K++ AA LL+++W +L R +G+
Sbjct: 750 FIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFRAKGY 789
>gi|4502247 armadillo repeat protein [Homo sapiens]
Length = 962
Score = 234 bits (598), Expect = 2e-61
Identities = 167/510 (32%), Positives = 255/510 (50%), Gaps = 51/510 (10%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + +A A Y+QH CF++E K++V QL G+ LV LL P V++
Sbjct: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GALRNL + R T NK R G+ V LLR + E+++ +TG LWNLSS + LK
Sbjct: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
Query: 366 ELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE---VFFNATGCLRKRLGMRELLAL 422
+I L L VI+P SGW + N + D E VF N +GCLR
Sbjct: 480 VIIDHGLQTLTHEVIVPHSGW-EREPNEDSKPRDAEWTTVFKNTSGCLR----------- 527
Query: 423 VPQRATSSRVNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN 481
N+SS A R+ +R GL+D+L+ +Q+ V D+KSVENC+C++ N
Sbjct: 528 ----------NVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577
Query: 482 LSYRLDAEVP--TRYRQLEYNARNAYT-----EKSSTGCF-----------SNKSDKMMN 523
LSY + EVP RY++ E + + CF K D M+
Sbjct: 578 LSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMD 637
Query: 524 NNYD-CPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLM 582
N+D LP+ KG LY + +R YL+L+ +S+ TLEA AGALQNL+A +
Sbjct: 638 RNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMW 697
Query: 583 SSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTR 642
++ + + KE+GLP + LLQS VVR+ A L N+S ++G+ E+ R
Sbjct: 698 ATYIRATV-RKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVR 756
Query: 643 LLTSHTG----NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP 698
+ + ED + + T+ +++ A+ + + ++ L SS S
Sbjct: 757 NVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSV 816
Query: 699 KAAEAARLLLSDMWSSKELQGVLRQQGFDR 728
+ A+AA +L +WS KEL+G L++ G+ +
Sbjct: 817 REAKAASHVLQTVWSYKELRGTLQKDGWTK 846
>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 434
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 435 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 485
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 486 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 541
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 542 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 600
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 601 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 660
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 661 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 720
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 721 TIWGYKELRKPLEKEGWKKS 740
>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 434
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 435 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 485
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 486 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 541
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 542 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 600
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 601 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 660
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 661 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 720
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 721 TIWGYKELRKPLEKEGWKKS 740
>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 434
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 435 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 485
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 486 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 541
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 542 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 600
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 601 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 660
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 661 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 720
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 721 TIWGYKELRKPLEKEGWKKS 740
>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
Length = 840
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 434
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 435 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 485
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 486 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 541
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 542 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 600
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 601 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 660
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 661 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 720
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 721 TIWGYKELRKPLEKEGWKKS 740
>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
Length = 861
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 434
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 435 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 485
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 486 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 541
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 542 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 600
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 601 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 660
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 661 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 720
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 721 TIWGYKELRKPLEKEGWKKS 740
>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 535
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 536 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 586
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 587 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 642
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 643 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 701
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 702 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 761
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 762 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 821
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 822 TIWGYKELRKPLEKEGWKKS 841
>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 535
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 536 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 586
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 587 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 642
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 643 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 701
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 702 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 761
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 762 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 821
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 822 TIWGYKELRKPLEKEGWKKS 841
>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 535
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 536 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 586
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 587 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 642
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 643 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 701
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 702 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 761
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 762 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 821
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 822 TIWGYKELRKPLEKEGWKKS 841
>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
Length = 941
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 535
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 536 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 586
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 587 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 642
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 643 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 701
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 702 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 761
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 762 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 821
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 822 TIWGYKELRKPLEKEGWKKS 841
>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
Length = 962
Score = 218 bits (555), Expect = 2e-56
Identities = 156/500 (31%), Positives = 252/500 (50%), Gaps = 43/500 (8%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 535
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 536 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 586
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEE 533
SY++ E+P RY++ N N T + CF K K N+ D P +
Sbjct: 587 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---K 642
Query: 534 ETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGL 592
T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + + +
Sbjct: 643 RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-R 701
Query: 593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS 652
+EK L IA LL + + VV++ + L N++ ++G P + + L N+S
Sbjct: 702 QEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSS 761
Query: 653 --NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLS 709
SED + S T+ ++A + AK+ + + ++ + +S + S K AA L+L
Sbjct: 762 WNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQ 821
Query: 710 DMWSSKELQGVLRQQGFDRN 729
+W KEL+ L ++G+ ++
Sbjct: 822 TIWGYKELRKPLEKEGWKKS 841
>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
Length = 838
Score = 216 bits (549), Expect = 8e-56
Identities = 156/506 (30%), Positives = 252/506 (49%), Gaps = 49/506 (9%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 434
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 435 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 485
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------------MMNNNYD 527
SY++ E+P RY++ N N T + CF K K N+ D
Sbjct: 486 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 544
Query: 528 CPLPEEETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGM 586
P + T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + +
Sbjct: 545 FP---KRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYI 601
Query: 587 SQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTS 646
+ +EK L IA LL + + VV++ + L N++ ++G P + + L
Sbjct: 602 RSAL-RQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 660
Query: 647 HTGNTS--NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEA 703
N+S SED + S T+ ++A + AK+ + + ++ + +S + S K A
Sbjct: 661 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRA 720
Query: 704 ARLLLSDMWSSKELQGVLRQQGFDRN 729
A L+L +W KEL+ L ++G+ ++
Sbjct: 721 AALVLQTIWGYKELRKPLEKEGWKKS 746
>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
Length = 867
Score = 216 bits (549), Expect = 8e-56
Identities = 156/506 (30%), Positives = 252/506 (49%), Gaps = 49/506 (9%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 434
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 435 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 485
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------------MMNNNYD 527
SY++ E+P RY++ N N T + CF K K N+ D
Sbjct: 486 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 544
Query: 528 CPLPEEETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGM 586
P + T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + +
Sbjct: 545 FP---KRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYI 601
Query: 587 SQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTS 646
+ +EK L IA LL + + VV++ + L N++ ++G P + + L
Sbjct: 602 RSAL-RQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 660
Query: 647 HTGNTS--NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEA 703
N+S SED + S T+ ++A + AK+ + + ++ + +S + S K A
Sbjct: 661 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRA 720
Query: 704 ARLLLSDMWSSKELQGVLRQQGFDRN 729
A L+L +W KEL+ L ++G+ ++
Sbjct: 721 AALVLQTIWGYKELRKPLEKEGWKKS 746
>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
Length = 968
Score = 216 bits (549), Expect = 8e-56
Identities = 156/506 (30%), Positives = 252/506 (49%), Gaps = 49/506 (9%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALV 423
E++ AL L D VIIP SGW + N + R + V N GCLR
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLR------------ 535
Query: 424 PQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 482
N+SS R+ +R GL+D+L+ VQ + D K VENC+C+L NL
Sbjct: 536 ---------NVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNL 586
Query: 483 SYRLDAEVP--TRYRQLEYNARNAYTEKSSTGCFSNKSDK-------------MMNNNYD 527
SY++ E+P RY++ N N T + CF K K N+ D
Sbjct: 587 SYQVHREIPQAERYQEAAPNVAN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVD 645
Query: 528 CPLPEEETNP-KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGM 586
P + T+P +G L+ + +R Y++L+ +SK A LEA AGA+QNL A + +
Sbjct: 646 FP---KRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYI 702
Query: 587 SQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTS 646
+ +EK L IA LL + + VV++ + L N++ ++G P + + L
Sbjct: 703 RSAL-RQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPG 761
Query: 647 HTGNTS--NSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEA 703
N+S SED + S T+ ++A + AK+ + + ++ + +S + S K A
Sbjct: 762 GQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRA 821
Query: 704 ARLLLSDMWSSKELQGVLRQQGFDRN 729
A L+L +W KEL+ L ++G+ ++
Sbjct: 822 AALVLQTIWGYKELRKPLEKEGWKKS 847
>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
Length = 872
Score = 41.6 bits (96), Expect = 0.003
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 251 VQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGA 310
V L S+++ + + I C + S + + GI +L+ LL+S N+ V++AAA A
Sbjct: 322 VALLGSENDGTKIAASQAISAMC--ENSGSKDFFNNQGIPQLIQLLKSDNEEVREAAALA 379
Query: 311 LRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
L NL + N +GI ++LL + I T +L N++ + L+
Sbjct: 380 LANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAAT-VLTNMAMQEPLR 432
Score = 37.0 bits (84), Expect = 0.067
Identities = 42/182 (23%), Positives = 79/182 (43%), Gaps = 21/182 (11%)
Query: 543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 602
L+H + L + S+ D T A + A+ + + G +Q G+PQ+ +
Sbjct: 311 LFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQ-------GIPQLIQ 363
Query: 603 LLQSGNSDVVRSGASLLSNMSR-HPLLHRVM--GNQVFPEVTRLLTSHTGNTSNSEDILS 659
LL+S N +V + A L+N++ +P + + P + L + G +N+ +L+
Sbjct: 364 LLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLT 423
Query: 660 SACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS---ASPKAAEAARLLLSDMWSSKE 716
+ MA Q L + +++ II+ RS+ KAA A D+ + E
Sbjct: 424 N--------MAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTE 475
Query: 717 LQ 718
L+
Sbjct: 476 LR 477
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 9/135 (6%)
Query: 227 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 286
G +A +++ D E GLT + S +Y + + + F D + K + +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522
Query: 287 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 344
G + LV L+S ++++QQ A LRNL +R+ N +T R+ G ++ +
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582
Query: 345 EIQKQLTGLLWNLSS 359
K + LWNLS+
Sbjct: 583 STLKSVLSALWNLSA 597
Score = 38.9 bits (89), Expect = 0.018
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 619
KK++TL++ AL NL+A + + + G + + Q+ ++ SG +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639
Query: 620 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 679
N+S + Q+ E L T S+S I+S+AC T+ NL A P+ +
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698
Query: 680 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 710
+ + SML N+I+ + +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 9/135 (6%)
Query: 227 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 286
G +A +++ D E GLT + S +Y + + + F D + K + +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522
Query: 287 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 344
G + LV L+S ++++QQ A LRNL +R+ N +T R+ G ++ +
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582
Query: 345 EIQKQLTGLLWNLSS 359
K + LWNLS+
Sbjct: 583 STLKSVLSALWNLSA 597
Score = 38.9 bits (89), Expect = 0.018
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 619
KK++TL++ AL NL+A + + + G + + Q+ ++ SG +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639
Query: 620 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 679
N+S + Q+ E L T S+S I+S+AC T+ NL A P+ +
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698
Query: 680 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 710
+ + SML N+I+ + +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 9/135 (6%)
Query: 227 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 286
G +A +++ D E GLT + S +Y + + + F D + K + +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522
Query: 287 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 344
G + LV L+S ++++QQ A LRNL +R+ N +T R+ G ++ +
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582
Query: 345 EIQKQLTGLLWNLSS 359
K + LWNLS+
Sbjct: 583 STLKSVLSALWNLSA 597
Score = 38.9 bits (89), Expect = 0.018
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 619
KK++TL++ AL NL+A + + + G + + Q+ ++ SG +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639
Query: 620 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 679
N+S + Q+ E L T S+S I+S+AC T+ NL A P+ +
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698
Query: 680 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 710
+ + SML N+I+ + +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732
>gi|155030194 RAP1, GTP-GDP dissociation stimulator 1 isoform 2
[Homo sapiens]
Length = 607
Score = 38.9 bits (89), Expect = 0.018
Identities = 42/153 (27%), Positives = 65/153 (42%), Gaps = 13/153 (8%)
Query: 244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL----RSP 299
G + + ++ S + + Q GA I + D + V G + KL+DLL
Sbjct: 316 GSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDN-GIVEKLMDLLDRHVEDG 374
Query: 300 NQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS 359
N VQ AA ALRNL NK + G+ EAV ++ +Q +L G L L
Sbjct: 375 NVTVQHAALSALRNLAI-PVINKAKMLSA-GVTEAVLKFLKSEMPPVQFKLLGTLRMLID 432
Query: 360 TDELKEELIADALPVLADRVIIPFSGWCDGNSN 392
E E+L + L +R++ WC+ +
Sbjct: 433 AQEAAEQLGKNV--KLVERLV----EWCEAKDH 459
Score = 30.4 bits (67), Expect = 6.3
Identities = 46/199 (23%), Positives = 80/199 (40%), Gaps = 14/199 (7%)
Query: 243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS---- 298
+GL P VQ L+S+D++ + + C+ + V Q GG ++D LRS
Sbjct: 89 AGLISP-LVQLLNSKDQEVLLQTGRALGNICYDSHEGRSAVDQAGGAQIVIDHLRSLCSI 147
Query: 299 ---PNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLR-RTGNAEIQKQLTGLL 354
N+ + G L N + + + + I V LL NA + +
Sbjct: 148 TDPANEKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAF 207
Query: 355 WNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNS-NMSREVVDPEVFFNATGCLRKR 413
NL+ + KE+ A +A+ ++ F + + M EV+ P +A
Sbjct: 208 GNLAELESSKEQF---ASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVE 264
Query: 414 LGMRE-LLALVPQRATSSR 431
G+ E LL +V Q+ S +
Sbjct: 265 AGLVECLLEIVQQKVDSDK 283
>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 37.7 bits (86), Expect = 0.039
Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 24/265 (9%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
IP V+ L S + + + E AK V GG+ K+V LL N
Sbjct: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
Query: 307 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEE 366
L+ L + + +KL G + V+++R ++ + +L LS K
Sbjct: 297 TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPA 356
Query: 367 LI-ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF--NATGCLRKRLGMRELLALV 423
++ A + L + P S+ +V ++ N + K+ GM LL +
Sbjct: 357 IVEAGGMQALGLHLTDP-----------SQRLVQNCLWTLRNLSDAATKQEGMEGLLGTL 405
Query: 424 PQRATSSRVNLSSADAG---RQTMRNYSG-----LIDSLMAYVQNCVAASRCDDKSVENC 475
Q S +N+ + AG T NY + + A V+ + A +D E
Sbjct: 406 VQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDRED-ITEPA 464
Query: 476 MCVLHNLSYR-LDAEVPTRYRQLEY 499
+C L +L+ R +AE+ +L Y
Sbjct: 465 ICALRHLTSRHQEAEMAQNAVRLHY 489
>gi|148233338 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 37.7 bits (86), Expect = 0.039
Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 24/265 (9%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
IP V+ L S + + + E AK V GG+ K+V LL N
Sbjct: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
Query: 307 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEE 366
L+ L + + +KL G + V+++R ++ + +L LS K
Sbjct: 297 TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPA 356
Query: 367 LI-ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF--NATGCLRKRLGMRELLALV 423
++ A + L + P S+ +V ++ N + K+ GM LL +
Sbjct: 357 IVEAGGMQALGLHLTDP-----------SQRLVQNCLWTLRNLSDAATKQEGMEGLLGTL 405
Query: 424 PQRATSSRVNLSSADAG---RQTMRNYSG-----LIDSLMAYVQNCVAASRCDDKSVENC 475
Q S +N+ + AG T NY + + A V+ + A +D E
Sbjct: 406 VQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDRED-ITEPA 464
Query: 476 MCVLHNLSYR-LDAEVPTRYRQLEY 499
+C L +L+ R +AE+ +L Y
Sbjct: 465 ICALRHLTSRHQEAEMAQNAVRLHY 489
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.128 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,721,256
Number of Sequences: 37866
Number of extensions: 1154363
Number of successful extensions: 3139
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2913
Number of HSP's gapped (non-prelim): 143
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.