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Search of human proteins with 53729344
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
(726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens] 1462 0.0
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens] 1450 0.0
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ... 1259 0.0
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens] 362 e-100
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens] 341 1e-93
gi|53829376 plakophilin 4 isoform b [Homo sapiens] 273 5e-73
gi|53829374 plakophilin 4 isoform a [Homo sapiens] 273 5e-73
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur... 263 3e-70
gi|6005830 plakophilin 3 [Homo sapiens] 259 6e-69
gi|4502247 armadillo repeat protein [Homo sapiens] 247 3e-65
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens] 230 3e-60
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens] 230 3e-60
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens] 230 3e-60
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens] 230 3e-60
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens] 230 3e-60
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens] 230 3e-60
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens] 230 3e-60
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens] 230 3e-60
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens] 230 3e-60
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens] 230 3e-60
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens] 228 2e-59
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens] 228 2e-59
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens] 228 2e-59
gi|4504811 junction plakoglobin [Homo sapiens] 46 1e-04
gi|12056468 junction plakoglobin [Homo sapiens] 46 1e-04
gi|189011568 adenomatous polyposis coli [Homo sapiens] 42 0.003
gi|189011566 adenomatous polyposis coli [Homo sapiens] 42 0.003
gi|53759122 adenomatous polyposis coli [Homo sapiens] 42 0.003
gi|189409124 armadillo repeat containing 3 [Homo sapiens] 42 0.003
gi|148227672 catenin (cadherin-associated protein), beta 1, 88kD... 41 0.004
>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
Length = 726
Score = 1462 bits (3786), Expect = 0.0
Identities = 726/726 (100%), Positives = 726/726 (100%)
Query: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS
Sbjct: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
Query: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY
Sbjct: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
Query: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT
Sbjct: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
Query: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI
Sbjct: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
Query: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN
Sbjct: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
Query: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST
Sbjct: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
Query: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADAGR 420
DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADAGR
Sbjct: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADAGR 420
Query: 421 QTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNA 480
QTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNA
Sbjct: 421 QTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNA 480
Query: 481 RNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK 540
RNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK
Sbjct: 481 RNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK 540
Query: 541 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSN 600
DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSN
Sbjct: 541 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSN 600
Query: 601 MSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS 660
MSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS
Sbjct: 601 MSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS 660
Query: 661 SSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLR 720
SSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLR
Sbjct: 661 SSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGANSLR 720
Query: 721 NFTSRF 726
NFTSRF
Sbjct: 721 NFTSRF 726
>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
Length = 747
Score = 1450 bits (3754), Expect = 0.0
Identities = 726/747 (97%), Positives = 726/747 (97%), Gaps = 21/747 (2%)
Query: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS
Sbjct: 1 MNHSPLKTALAYECFQDQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVKRQKSKSSQSS 60
Query: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY
Sbjct: 61 TLSHSNRGSMYDGLADNYNYGTTSRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRRFSSY 120
Query: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT
Sbjct: 121 SQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYCDPRGTLRKGTLGSKGQKTT 180
Query: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI
Sbjct: 181 QNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCNKDLSFGHSRASSKICSEDI 240
Query: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN
Sbjct: 241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPN 300
Query: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST
Sbjct: 301 QNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST 360
Query: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLR--------- 411
DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLR
Sbjct: 361 DELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELL 420
Query: 412 ------------NLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH 459
NLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH
Sbjct: 421 ALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH 480
Query: 460 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS 519
NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS
Sbjct: 481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGS 540
Query: 520 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI 579
GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI
Sbjct: 541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQI 600
Query: 580 ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS 639
ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS
Sbjct: 601 ARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSS 660
Query: 640 ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV 699
ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV
Sbjct: 661 ACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGV 720
Query: 700 LRQQGFDRNMLGTLAGANSLRNFTSRF 726
LRQQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 721 LRQQGFDRNMLGTLAGANSLRNFTSRF 747
>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
sapiens]
Length = 625
Score = 1259 bits (3257), Expect = 0.0
Identities = 625/625 (100%), Positives = 625/625 (100%)
Query: 102 PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 161
PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC
Sbjct: 1 PIYNGTLKREPDNRRFSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKIKASRSEPDLYC 60
Query: 162 DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 221
DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN
Sbjct: 61 DPRGTLRKGTLGSKGQKTTQNRYSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIPPISCN 120
Query: 222 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 281
KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ
Sbjct: 121 KDLSFGHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ 180
Query: 282 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 341
QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT
Sbjct: 181 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT 240
Query: 342 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 401
GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE
Sbjct: 241 GNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE 300
Query: 402 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 461
VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL
Sbjct: 301 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 360
Query: 462 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW 521
SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW
Sbjct: 361 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW 420
Query: 522 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 581
LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR
Sbjct: 421 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 480
Query: 582 LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC 641
LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC
Sbjct: 481 LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSAC 540
Query: 642 YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR 701
YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR
Sbjct: 541 YTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQGVLR 600
Query: 702 QQGFDRNMLGTLAGANSLRNFTSRF 726
QQGFDRNMLGTLAGANSLRNFTSRF
Sbjct: 601 QQGFDRNMLGTLAGANSLRNFTSRF 625
>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
Length = 837
Score = 362 bits (930), Expect = e-100
Identities = 198/482 (41%), Positives = 300/482 (62%), Gaps = 10/482 (2%)
Query: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290
S++ + D+E +T+ +AV L + I A +IQH CFQ A+++V QL GI
Sbjct: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
Query: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350
KL+ LL+ N++VQ+A GALRNLVF NKLE NG+ + +L++T + E +KQ+
Sbjct: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
Query: 351 TGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCL 410
TGLLWNLSS D+LK +I +AL L + +IIPFSGW +G+ + ++D ++F+N TGCL
Sbjct: 459 TGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCL 518
Query: 411 RNLSSADA-GRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEV 469
RN+SSA A GR+ MR GLIDSL+ YV+ +A + DDK+ ENC+C+LHNLSY+L+AE+
Sbjct: 519 RNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAEL 578
Query: 470 PTRYRQLEY-NARNAYTEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDA 527
P +Y Q Y RN T+ + S GCF ++S K+ D P+PEE++NPKG WL+HS
Sbjct: 579 PEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIV 638
Query: 528 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN 587
IR YL+L+ KS ++ T EA GALQNLTA G M + ++Q + KE GL ++L G+
Sbjct: 639 IRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGD 698
Query: 588 SDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNL 647
V ++ SLL N+SR+ L + + P++ ++ +T + +SACYT+ N+
Sbjct: 699 PSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNI 758
Query: 648 MASQPQLAKQYFSSSMLNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGF 705
+ + Q A+ ++ + I+ + AS KA++AA +LL +W+ EL ++ F
Sbjct: 759 IQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQF 818
Query: 706 DR 707
+
Sbjct: 819 KK 820
Score = 39.7 bits (91), Expect = 0.010
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)
Query: 6 LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57
++T L + D+S+LALPS+ K+K G+SGR R+QEQV T+ R+ S
Sbjct: 13 IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
Query: 58 QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108
+ L ++ Y + +++ G + Y +AG G WG GT
Sbjct: 73 GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
Query: 109 KREPDNRRFSSYSQMENWSRHYP 131
++SS +E S +P
Sbjct: 128 ------AQYSSQKSVEERSLRHP 144
>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
Length = 881
Score = 341 bits (875), Expect = 1e-93
Identities = 198/526 (37%), Positives = 300/526 (57%), Gaps = 54/526 (10%)
Query: 233 SKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAY--YIQHTCFQDESAKQQVYQLGGIC 290
S++ + D+E +T+ +AV L + I A +IQH CFQ A+++V QL GI
Sbjct: 342 SQLGNADME---MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGIL 398
Query: 291 KLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL 350
KL+ LL+ N++VQ+A GALRNLVF NKLE NG+ + +L++T + E +KQ+
Sbjct: 399 KLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQI 458
Query: 351 T--------------------------------------------GLLWNLSSTDELKEE 366
T GLLWNLSS D+LK
Sbjct: 459 TDHTVNLRSRNGWPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNL 518
Query: 367 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRNLSSADA-GRQTMRN 425
+I +AL L + +IIPFSGW +G+ + ++D ++F+N TGCLRN+SSA A GR+ MR
Sbjct: 519 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRR 578
Query: 426 YSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEY-NARNAY 484
GLIDSL+ YV+ +A + DDK+ ENC+C+LHNLSY+L+AE+P +Y Q Y RN
Sbjct: 579 CDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNIYIQNRNIQ 638
Query: 485 TEKS-STGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT 543
T+ + S GCF ++S K+ D P+PEE++NPKG WL+HS IR YL+L+ KS ++ T
Sbjct: 639 TDNNKSIGCFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRNYT 698
Query: 544 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 603
EA GALQNLTA G M + ++Q + KE GL ++L G+ V ++ SLL N+SR
Sbjct: 699 QEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNLSR 758
Query: 604 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM 663
+ L + + P++ ++ +T + +SACYT+ N++ + Q A+ ++
Sbjct: 759 NLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNTGG 818
Query: 664 LNNIINLCRSS--ASPKAAEAARLLLSDMWSSKELQGVLRQQGFDR 707
+ I+ + AS KA++AA +LL +W+ EL ++ F +
Sbjct: 819 IQKIMAISAGDAYASNKASKAASVLLYSLWAHTELHHAYKKAQFKK 864
Score = 39.7 bits (91), Expect = 0.010
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 28/143 (19%)
Query: 6 LKTALAYECFQDQDNSTLALPSDQKMK-TGTSGR-------QRVQEQVMMTVKRQKSKSS 57
++T L + D+S+LALPS+ K+K G+SGR R+QEQV T+ R+ S
Sbjct: 13 IRTVLGQQILGQLDSSSLALPSEAKLKLAGSSGRGGQTVKSLRIQEQVQQTLARKGRSSV 72
Query: 58 QSSTLSHSNRGSMY----DGLADNYNYGTTSRSSYYSKFQAG-----NGSWGYPIYNGTL 108
+ L ++ Y + +++ G + Y +AG G WG GT
Sbjct: 73 GNGNLHRTSSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKAGTTATYEGRWG----RGT- 127
Query: 109 KREPDNRRFSSYSQMENWSRHYP 131
++SS +E S +P
Sbjct: 128 ------AQYSSQKSVEERSLRHP 144
>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
Length = 1149
Score = 273 bits (697), Expect = 5e-73
Identities = 168/482 (34%), Positives = 262/482 (54%), Gaps = 22/482 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L Q QA A Y+QH CF D K +V +LGGI LVDLL VQ+
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
Query: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
A GALRNLVF +T NK+ + GI + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 590 ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
Query: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRNLSSA-DAGRQ 421
+I DAL L + VI+P SGW + + + ++ V N TGCLRNLSSA + R+
Sbjct: 650 MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARK 709
Query: 422 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYN-- 479
MR+ GL+DSL+ + CV S D K+VENC+C L NLSYRL+ EVP + R L N
Sbjct: 710 QMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVP-QARLLGLNEL 768
Query: 480 ----ARNAYTEKSSTGCFSNKSDKMMNNNYD------CPLPEEETNPKGSGWLYHSDAIR 529
+ + ++ S C+ K K + P+P +PKG L+H ++
Sbjct: 769 DDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828
Query: 530 TYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD 589
YL L+ +S ATLE AG+LQNL+A ++ + + KEKGLP + LL+ N
Sbjct: 829 PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV-RKEKGLPILVELLRMDNDR 887
Query: 590 VVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA 649
VV S A+ L NM+ ++G ++ L G + S++ +++ C + + +
Sbjct: 888 VVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTS 947
Query: 650 SQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARLLLSDMWSSKELQGVLRQQGFD 706
+ AK S + ++N+ + +S K +AA +L+ +W ++L+ + ++ G++
Sbjct: 948 KNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWN 1007
Query: 707 RN 708
+N
Sbjct: 1008 QN 1009
>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
Length = 1192
Score = 273 bits (697), Expect = 5e-73
Identities = 168/482 (34%), Positives = 262/482 (54%), Gaps = 22/482 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L Q QA A Y+QH CF D K +V +LGGI LVDLL VQ+
Sbjct: 530 LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
Query: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
A GALRNLVF +T NK+ + GI + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 590 ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
Query: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRNLSSA-DAGRQ 421
+I DAL L + VI+P SGW + + + ++ V N TGCLRNLSSA + R+
Sbjct: 650 MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARK 709
Query: 422 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYN-- 479
MR+ GL+DSL+ + CV S D K+VENC+C L NLSYRL+ EVP + R L N
Sbjct: 710 QMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVP-QARLLGLNEL 768
Query: 480 ----ARNAYTEKSSTGCFSNKSDKMMNNNYD------CPLPEEETNPKGSGWLYHSDAIR 529
+ + ++ S C+ K K + P+P +PKG L+H ++
Sbjct: 769 DDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828
Query: 530 TYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD 589
YL L+ +S ATLE AG+LQNL+A ++ + + KEKGLP + LL+ N
Sbjct: 829 PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV-RKEKGLPILVELLRMDNDR 887
Query: 590 VVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA 649
VV S A+ L NM+ ++G ++ L G + S++ +++ C + + +
Sbjct: 888 VVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTS 947
Query: 650 SQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARLLLSDMWSSKELQGVLRQQGFD 706
+ AK S + ++N+ + +S K +AA +L+ +W ++L+ + ++ G++
Sbjct: 948 KNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWN 1007
Query: 707 RN 708
+N
Sbjct: 1008 QN 1009
>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
plakophilin-related arm-repeat protein) [Homo sapiens]
Length = 1225
Score = 263 bits (673), Expect = 3e-70
Identities = 170/487 (34%), Positives = 261/487 (53%), Gaps = 31/487 (6%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ +Q L Q Q+ A Y+QH CF D K ++ + GGI LVDLL V ++
Sbjct: 552 LPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRS 611
Query: 307 AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
A GALRNLV+ NK+ + GI V LLR+T + EI++ +TG+LWNLSS D LK
Sbjct: 612 ACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALK 671
Query: 365 EELIADALPVLADRVIIPFSGWCDGNSNMSREVV--DPEVFFNATGCLRNLSSA-DAGRQ 421
+I DAL VL + VIIP SGW + R++ +V NATGCLRN+SSA + R+
Sbjct: 672 MPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARR 731
Query: 422 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQ------ 475
MR GL D+L+ +Q+ + +S D K+VENC+C+L NLSYRL AE
Sbjct: 732 RMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELD 791
Query: 476 ----LEYNARNAYTEKSSTGCFSNKSDKMMN-NNYD--CPLPEEETNPKGSGWLYHSDAI 528
E N ++A S+GC+ K K + + +D PLP+ PKG L+H +
Sbjct: 792 GLLCGEANGKDA----ESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIV 847
Query: 529 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS 588
+ YL L+ + TLE AGALQNL A S + + KEKGLP + LL+ N
Sbjct: 848 KPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAV-RKEKGLPILVELLRIDND 906
Query: 589 DVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLL-----TSHTGNTSNSEDILSSACYT 643
VV + A+ L NM+ ++G ++ L +++T + + S+D +++ C T
Sbjct: 907 RVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNTASKAMSDDTVTAVCCT 966
Query: 644 VRNLMASQPQLAKQYFSSSMLNNIINLCRSSA---SPKAAEAARLLLSDMWSSKELQGVL 700
+ ++ + AK + + ++ + +S SPK +AA +L+ MW ++L+ +
Sbjct: 967 LHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLY 1026
Query: 701 RQQGFDR 707
++ G+ +
Sbjct: 1027 KKDGWSQ 1033
>gi|6005830 plakophilin 3 [Homo sapiens]
Length = 797
Score = 259 bits (662), Expect = 6e-69
Identities = 172/499 (34%), Positives = 265/499 (53%), Gaps = 29/499 (5%)
Query: 225 SFGHSRASSKICS--EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQ 282
S+G R ++ S +DI+ +P AV+YL + D Q +GA YIQH C+ D +AK+Q
Sbjct: 302 SYGSHRTLQRLSSGFDDID-----LPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQ 356
Query: 283 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 342
L + +LV L NQ VQ+ A GA+RNL++ + NKL +NGI E + LR
Sbjct: 357 ARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQD 416
Query: 343 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 402
+ E++K +TG+LWNLSS+D LK+ L D L L D V+ P SG G + + + E+
Sbjct: 417 D-ELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSG-AGGPPLIQQNASEAEI 474
Query: 403 FFNATGCLRNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 461
F+NATG LRNLSSA A RQ MR GL+D+L+ + + + A +C+DKSVEN +CVL NL
Sbjct: 475 FYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNL 534
Query: 462 SYRL-DAEVPTRYRQLEYNARN---AYTEKSSTGCFSNKSDKMMNNNYDCPL-------P 510
SYRL D P+ ++LE R GCF+ +S ++ + PL
Sbjct: 535 SYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLR----ELPLAADALTFA 590
Query: 511 EEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA-TLEACAGALQNLTASKGLMSSGMSQLI 569
E +PKG WL+ + Y L+ + + + T EA AGALQN+TA + +S+L
Sbjct: 591 EVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLA 650
Query: 570 GLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGN 629
+E+ L + +++ + +RS L+ N+SR+ M +V + L G
Sbjct: 651 LEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGE 710
Query: 630 TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP---KAAEAARLL 686
S ++L + + NL+ + P A+ L +I + + SP K++ AA L
Sbjct: 711 KSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSL 770
Query: 687 LSDMWSSKELQGVLRQQGF 705
L+++W +L R +G+
Sbjct: 771 LANLWQYNKLHRDFRAKGY 789
>gi|4502247 armadillo repeat protein [Homo sapiens]
Length = 962
Score = 247 bits (630), Expect = 3e-65
Identities = 167/489 (34%), Positives = 255/489 (52%), Gaps = 30/489 (6%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + +A A Y+QH CF++E K++V QL G+ LV LL P V++
Sbjct: 360 LPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQLRGLPLLVALLDHPRAEVRRR 419
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GALRNL + R T NK R G+ V LLR + E+++ +TG LWNLSS + LK
Sbjct: 420 ACGALRNLSYGRDTDNKAAIRDCGGVPALVRLLRAARDNEVRELVTGTLWNLSSYEPLKM 479
Query: 366 ELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPE---VFFNATGCLRNLSSADA-GRQ 421
+I L L VI+P SGW + N + D E VF N +GCLRN+SS A R+
Sbjct: 480 VIIDHGLQTLTHEVIVPHSGW-EREPNEDSKPRDAEWTTVFKNTSGCLRNVSSDGAEARR 538
Query: 422 TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYN 479
+R GL+D+L+ +Q+ V D+KSVENC+C++ NLSY + EVP RY++ E
Sbjct: 539 RLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRNLSYHVHKEVPGADRYQEAEPG 598
Query: 480 ARNAYT-----EKSSTGCF-----------SNKSDKMMNNNYD-CPLPEEETNPKGSGWL 522
+ + CF K D M+ N+D LP+ KG L
Sbjct: 599 PLGSAVGSQRRRRDDASCFGGKKAKEEWFHQGKKDGEMDRNFDTLDLPKRTEAAKGFELL 658
Query: 523 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL 582
Y + +R YL+L+ +S+ TLEA AGALQNL+A + ++ + + KE+GLP + L
Sbjct: 659 YQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWMWATYIRATV-RKERGLPVLVEL 717
Query: 583 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTG----NTSNSEDILS 638
LQS VVR+ A L N+S ++G+ E+ R + + ED +
Sbjct: 718 LQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVRNVRNAQAPPRPGACLEEDTVV 777
Query: 639 SACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG 698
+ T+ +++ A+ + + ++ L SS S + A+AA +L +WS KEL+G
Sbjct: 778 AVLNTIHEIVSDSLDNARSLLQARGVPALVALVASSQSVREAKAASHVLQTVWSYKELRG 837
Query: 699 VLRQQGFDR 707
L++ G+ +
Sbjct: 838 TLQKDGWTK 846
>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740
>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740
>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
Length = 832
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740
>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
Length = 840
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740
>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
Length = 861
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 507 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 562
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 563 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 621
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 622 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 681
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 682 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 740
>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841
>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841
>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
Length = 933
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841
>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
Length = 941
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841
>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
Length = 962
Score = 230 bits (587), Expect = 3e-60
Identities = 156/479 (32%), Positives = 252/479 (52%), Gaps = 22/479 (4%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607
Query: 481 RNAYTEKSSTGCFSNKSDK-------MMNNNYDCPLPEEETNP-KGSGWLYHSDAIRTYL 532
N T + CF K K N+ D P + T+P +G L+ + +R Y+
Sbjct: 608 AN-NTGPHAASCFGAKKGKGKKPIEDPANDTVDFP---KRTSPARGYELLFQPEVVRIYI 663
Query: 533 NLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVR 592
+L+ +SK A LEA AGA+QNL A + + + +EK L IA LL + + VV+
Sbjct: 664 SLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNEHERVVK 722
Query: 593 SGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTVRNLMAS 650
+ + L N++ ++G P + + L N+S SED + S T+ ++A
Sbjct: 723 AASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTINEVIAE 782
Query: 651 QPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN 708
+ AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++G+ ++
Sbjct: 783 NLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKS 841
>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
Length = 838
Score = 228 bits (581), Expect = 2e-59
Identities = 156/485 (32%), Positives = 252/485 (51%), Gaps = 28/485 (5%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506
Query: 481 RNAYTEKSSTGCFSNKSDK-------------MMNNNYDCPLPEEETNP-KGSGWLYHSD 526
N T + CF K K N+ D P + T+P +G L+ +
Sbjct: 507 AN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFP---KRTSPARGYELLFQPE 562
Query: 527 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG 586
+R Y++L+ +SK A LEA AGA+QNL A + + + +EK L IA LL +
Sbjct: 563 VVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNE 621
Query: 587 NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTV 644
+ VV++ + L N++ ++G P + + L N+S SED + S T+
Sbjct: 622 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 681
Query: 645 RNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQ 703
++A + AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++
Sbjct: 682 NEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKE 741
Query: 704 GFDRN 708
G+ ++
Sbjct: 742 GWKKS 746
>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
Length = 867
Score = 228 bits (581), Expect = 2e-59
Identities = 156/485 (32%), Positives = 252/485 (51%), Gaps = 28/485 (5%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 267 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 326
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 327 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 386
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 387 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 446
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 447 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 506
Query: 481 RNAYTEKSSTGCFSNKSDK-------------MMNNNYDCPLPEEETNP-KGSGWLYHSD 526
N T + CF K K N+ D P + T+P +G L+ +
Sbjct: 507 AN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFP---KRTSPARGYELLFQPE 562
Query: 527 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG 586
+R Y++L+ +SK A LEA AGA+QNL A + + + +EK L IA LL +
Sbjct: 563 VVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNE 621
Query: 587 NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTV 644
+ VV++ + L N++ ++G P + + L N+S SED + S T+
Sbjct: 622 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 681
Query: 645 RNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQ 703
++A + AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++
Sbjct: 682 NEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKE 741
Query: 704 GFDRN 708
G+ ++
Sbjct: 742 GWKKS 746
>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
Length = 968
Score = 228 bits (581), Expect = 2e-59
Identities = 156/485 (32%), Positives = 252/485 (51%), Gaps = 28/485 (5%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
+P+ + L + + ++ A Y+QH C++++ K V +L GI LV LL P + V
Sbjct: 368 LPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLG 427
Query: 307 AAGALRNLVF-RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE 365
A GAL+N+ F R NK+ + +G+ V LLR+ + ++ + +TG LWNLSS D +K
Sbjct: 428 ACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKM 487
Query: 366 ELIADALPVLADRVIIPFSGW-CDGNSNMS-REVVDPEVFFNATGCLRNLSS-ADAGRQT 422
E++ AL L D VIIP SGW + N + R + V N GCLRN+SS R+
Sbjct: 488 EIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRK 547
Query: 423 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVP--TRYRQLEYNA 480
+R GL+D+L+ VQ + D K VENC+C+L NLSY++ E+P RY++ N
Sbjct: 548 LRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNV 607
Query: 481 RNAYTEKSSTGCFSNKSDK-------------MMNNNYDCPLPEEETNP-KGSGWLYHSD 526
N T + CF K K N+ D P + T+P +G L+ +
Sbjct: 608 AN-NTGPHAASCFGAKKGKDEWFSRGKKPIEDPANDTVDFP---KRTSPARGYELLFQPE 663
Query: 527 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG 586
+R Y++L+ +SK A LEA AGA+QNL A + + + +EK L IA LL +
Sbjct: 664 VVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSAL-RQEKALSAIADLLTNE 722
Query: 587 NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTS--NSEDILSSACYTV 644
+ VV++ + L N++ ++G P + + L N+S SED + S T+
Sbjct: 723 HERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSWNFSEDTVISILNTI 782
Query: 645 RNLMASQPQLAKQYFSSSMLNNIINLCRS-SASPKAAEAARLLLSDMWSSKELQGVLRQQ 703
++A + AK+ + + ++ + +S + S K AA L+L +W KEL+ L ++
Sbjct: 783 NEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKE 842
Query: 704 GFDRN 708
G+ ++
Sbjct: 843 GWKKS 847
>gi|4504811 junction plakoglobin [Homo sapiens]
Length = 745
Score = 45.8 bits (107), Expect = 1e-04
Identities = 97/471 (20%), Positives = 176/471 (37%), Gaps = 62/471 (13%)
Query: 269 IQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ 328
I H +++ GGI LV +L SP ++V A L NL+ K+ R
Sbjct: 208 ILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLA 267
Query: 329 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCD 388
+G+++ V LL + N + T L L+ ++ ++II +G
Sbjct: 268 DGLQKMVPLLNK-NNPKFLAITTDCLQLLAYGNQ-------------ESKLIILANGGPQ 313
Query: 389 GNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDD 448
+ R ++ + + L+ LS + + + G + A ++ + S
Sbjct: 314 ALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGG----MQALGKHLTSNS---P 366
Query: 449 KSVENCMCVLHNLS------YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN 502
+ V+NC+ L NLS L++ + QL + N T +TG SN + N
Sbjct: 367 RLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLT--CATGTLSNLT---CN 421
Query: 503 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMS 562
N+ + L T G L H+ ++ KD E AL++LT+
Sbjct: 422 NSKNKTL---VTQNSGVEALIHA--------ILRAGDKDDITEPAVCALRHLTSRH--PE 468
Query: 563 SGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASLLSNMSRHPLLHRVMGN-QVFPEVT 620
+ M+Q G+P I +LL N +V++ L+ N++ P H + V P +
Sbjct: 469 AEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLV 528
Query: 621 RLL--------------TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNN 666
+LL T + + C +++A P + F + +
Sbjct: 529 QLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPL 588
Query: 667 IINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGAN 717
+ L SS A +L ++ KE + +G ++ L N
Sbjct: 589 FVQLLYSSVE-NIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRN 638
Score = 40.4 bits (93), Expect = 0.006
Identities = 86/415 (20%), Positives = 148/415 (35%), Gaps = 87/415 (20%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
IP V+ LSS E + + E AK V G+ K+V LL N
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287
Query: 307 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT------------------------- 341
L+ L + + +KL G + V ++R
Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347
Query: 342 -----GNAEIQKQLTG--------LLWNLSSTDEL--KEELIADALPVLADRVIIPFSGW 386
G + K LT LW L + ++ K+E + L +L +++
Sbjct: 348 IVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQL------- 400
Query: 387 CDGNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRC 446
V D V ATG L NL+ ++ +T+ + +++L+ + + +
Sbjct: 401 ---------SVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI----HAILRAGD 447
Query: 447 DDKSVENCMCVLHNLSYR-LDAEVPTRYRQLEY---------NARNAY-TEKSSTGCFSN 495
D E +C L +L+ R +AE+ +L Y N N + K++ G N
Sbjct: 448 KDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRN 507
Query: 496 KSDKMMNNNYDCPLPEEETNPKGSGWLY--HSDAIR-----TYLNLMGKSKKDATLEACA 548
+ N+ PL E P+ L H DA R T + + +E C
Sbjct: 508 LALCPANH---APLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCT 564
Query: 549 GALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 603
GAL L M+++ + +P +LL S ++ R A +L +++
Sbjct: 565 GALHILARDP------MNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQ 613
>gi|12056468 junction plakoglobin [Homo sapiens]
Length = 745
Score = 45.8 bits (107), Expect = 1e-04
Identities = 97/471 (20%), Positives = 176/471 (37%), Gaps = 62/471 (13%)
Query: 269 IQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ 328
I H +++ GGI LV +L SP ++V A L NL+ K+ R
Sbjct: 208 ILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLA 267
Query: 329 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCD 388
+G+++ V LL + N + T L L+ ++ ++II +G
Sbjct: 268 DGLQKMVPLLNK-NNPKFLAITTDCLQLLAYGNQ-------------ESKLIILANGGPQ 313
Query: 389 GNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDD 448
+ R ++ + + L+ LS + + + G + A ++ + S
Sbjct: 314 ALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGG----MQALGKHLTSNS---P 366
Query: 449 KSVENCMCVLHNLS------YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN 502
+ V+NC+ L NLS L++ + QL + N T +TG SN + N
Sbjct: 367 RLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLT--CATGTLSNLT---CN 421
Query: 503 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMS 562
N+ + L T G L H+ ++ KD E AL++LT+
Sbjct: 422 NSKNKTL---VTQNSGVEALIHA--------ILRAGDKDDITEPAVCALRHLTSRH--PE 468
Query: 563 SGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASLLSNMSRHPLLHRVMGN-QVFPEVT 620
+ M+Q G+P I +LL N +V++ L+ N++ P H + V P +
Sbjct: 469 AEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLV 528
Query: 621 RLL--------------TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNN 666
+LL T + + C +++A P + F + +
Sbjct: 529 QLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPL 588
Query: 667 IINLCRSSASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGAN 717
+ L SS A +L ++ KE + +G ++ L N
Sbjct: 589 FVQLLYSSVE-NIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRN 638
Score = 40.4 bits (93), Expect = 0.006
Identities = 86/415 (20%), Positives = 148/415 (35%), Gaps = 87/415 (20%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
IP V+ LSS E + + E AK V G+ K+V LL N
Sbjct: 228 IPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAI 287
Query: 307 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRT------------------------- 341
L+ L + + +KL G + V ++R
Sbjct: 288 TTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPA 347
Query: 342 -----GNAEIQKQLTG--------LLWNLSSTDEL--KEELIADALPVLADRVIIPFSGW 386
G + K LT LW L + ++ K+E + L +L +++
Sbjct: 348 IVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQL------- 400
Query: 387 CDGNSNMSREVVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRC 446
V D V ATG L NL+ ++ +T+ + +++L+ + + +
Sbjct: 401 ---------SVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALI----HAILRAGD 447
Query: 447 DDKSVENCMCVLHNLSYR-LDAEVPTRYRQLEY---------NARNAY-TEKSSTGCFSN 495
D E +C L +L+ R +AE+ +L Y N N + K++ G N
Sbjct: 448 KDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRN 507
Query: 496 KSDKMMNNNYDCPLPEEETNPKGSGWLY--HSDAIR-----TYLNLMGKSKKDATLEACA 548
+ N+ PL E P+ L H DA R T + + +E C
Sbjct: 508 LALCPANH---APLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCT 564
Query: 549 GALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR 603
GAL L M+++ + +P +LL S ++ R A +L +++
Sbjct: 565 GALHILARDP------MNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQ 613
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/243 (24%), Positives = 98/243 (40%), Gaps = 27/243 (11%)
Query: 227 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 286
G +A +++ D E GLT + S +Y + + + F D + K + +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522
Query: 287 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 344
G + LV L+S ++++QQ A LRNL +R+ N +T R+ G ++ +
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582
Query: 345 EIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE 401
K + LWNLS+ E K ++ A AL L G +
Sbjct: 583 STLKSVLSALWNLSAHCTENKADICAVDGALAFLV------------GTLTYRSQTNTLA 630
Query: 402 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 461
+ + G LRN+SS A + R + L +Q+ + S V N L NL
Sbjct: 631 IIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSL---TIVSNACGTLWNL 687
Query: 462 SYR 464
S R
Sbjct: 688 SAR 690
Score = 38.9 bits (89), Expect = 0.017
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 539 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 598
KK++TL++ AL NL+A + + + G + + Q+ ++ SG +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639
Query: 599 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 658
N+S + Q+ E L T S+S I+S+AC T+ NL A P+ +
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698
Query: 659 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 689
+ + SML N+I+ + +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/243 (24%), Positives = 98/243 (40%), Gaps = 27/243 (11%)
Query: 227 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 286
G +A +++ D E GLT + S +Y + + + F D + K + +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522
Query: 287 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 344
G + LV L+S ++++QQ A LRNL +R+ N +T R+ G ++ +
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582
Query: 345 EIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE 401
K + LWNLS+ E K ++ A AL L G +
Sbjct: 583 STLKSVLSALWNLSAHCTENKADICAVDGALAFLV------------GTLTYRSQTNTLA 630
Query: 402 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 461
+ + G LRN+SS A + R + L +Q+ + S V N L NL
Sbjct: 631 IIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSL---TIVSNACGTLWNL 687
Query: 462 SYR 464
S R
Sbjct: 688 SAR 690
Score = 38.9 bits (89), Expect = 0.017
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 539 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 598
KK++TL++ AL NL+A + + + G + + Q+ ++ SG +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639
Query: 599 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 658
N+S + Q+ E L T S+S I+S+AC T+ NL A P+ +
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698
Query: 659 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 689
+ + SML N+I+ + +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 41.6 bits (96), Expect = 0.003
Identities = 60/243 (24%), Positives = 98/243 (40%), Gaps = 27/243 (11%)
Query: 227 GHSRASSKICSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL 286
G +A +++ D E GLT + S +Y + + + F D + K + +
Sbjct: 470 GGLQAIAELLQVDCEMYGLTN----DHYSITLRRYAGMA---LTNLTFGDVANKATLCSM 522
Query: 287 GGICK-LVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTGNA 344
G + LV L+S ++++QQ A LRNL +R+ N +T R+ G ++ +
Sbjct: 523 KGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKE 582
Query: 345 EIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE 401
K + LWNLS+ E K ++ A AL L G +
Sbjct: 583 STLKSVLSALWNLSAHCTENKADICAVDGALAFLV------------GTLTYRSQTNTLA 630
Query: 402 VFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL 461
+ + G LRN+SS A + R + L +Q+ + S V N L NL
Sbjct: 631 IIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSL---TIVSNACGTLWNL 687
Query: 462 SYR 464
S R
Sbjct: 688 SAR 690
Score = 38.9 bits (89), Expect = 0.017
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 4/154 (2%)
Query: 539 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL 598
KK++TL++ AL NL+A + + + G + + Q+ ++ SG +L
Sbjct: 580 KKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGIL 639
Query: 599 SNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY 658
N+S + Q+ E L T S+S I+S+AC T+ NL A P+ +
Sbjct: 640 RNVS-SLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEAL 698
Query: 659 F---SSSMLNNIINLCRSSASPKAAEAARLLLSD 689
+ + SML N+I+ + +A A R L+++
Sbjct: 699 WDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMAN 732
>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
Length = 872
Score = 41.6 bits (96), Expect = 0.003
Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Query: 251 VQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGA 310
V L S+++ + + I C + S + + GI +L+ LL+S N+ V++AAA A
Sbjct: 322 VALLGSENDGTKIAASQAISAMC--ENSGSKDFFNNQGIPQLIQLLKSDNEEVREAAALA 379
Query: 311 LRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364
L NL + N +GI ++LL + I T +L N++ + L+
Sbjct: 380 LANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAAT-VLTNMAMQEPLR 432
Score = 37.0 bits (84), Expect = 0.065
Identities = 42/182 (23%), Positives = 79/182 (43%), Gaps = 21/182 (11%)
Query: 522 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR 581
L+H + L + S+ D T A + A+ + + G +Q G+PQ+ +
Sbjct: 311 LFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQ-------GIPQLIQ 363
Query: 582 LLQSGNSDVVRSGASLLSNMSR-HPLLHRVM--GNQVFPEVTRLLTSHTGNTSNSEDILS 638
LL+S N +V + A L+N++ +P + + P + L + G +N+ +L+
Sbjct: 364 LLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLT 423
Query: 639 SACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS---ASPKAAEAARLLLSDMWSSKE 695
+ MA Q L + +++ II+ RS+ KAA A D+ + E
Sbjct: 424 N--------MAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTE 475
Query: 696 LQ 697
L+
Sbjct: 476 LR 477
>gi|148227672 catenin (cadherin-associated protein), beta 1, 88kDa
[Homo sapiens]
Length = 781
Score = 40.8 bits (94), Expect = 0.004
Identities = 77/350 (22%), Positives = 142/350 (40%), Gaps = 49/350 (14%)
Query: 283 VYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG 342
+++ GGI LV +L SP +V A L NL+ K+ R G+++ V+LL +T
Sbjct: 231 IFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT- 289
Query: 343 NAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV 402
N + T L L+ ++ ++II SG N+ R ++
Sbjct: 290 NVKFLAITTDCLQILAYGNQ-------------ESKLIILASGGPQALVNIMRTYTYEKL 336
Query: 403 FFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS 462
+ + L+ LS + + + G+ +L ++ + + V+NC+ L NLS
Sbjct: 337 LWTTSRVLKVLSVCSSNKPAIVEAGGM-QALGLHLTD------PSQRLVQNCLWTLRNLS 389
Query: 463 ------YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKS-DKMMNNNYDCPLPEEETN 515
++ + T + L + N T + G SN + + N C + E
Sbjct: 390 DAATKQEGMEGLLGTLVQLLGSDDINVVT--CAAGILSNLTCNNYKNKMMVCQVGGIEA- 446
Query: 516 PKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKG 575
+RT L ++D T E AL++LT+ + M+Q G
Sbjct: 447 -----------LVRTVLR--AGDREDIT-EPAICALRHLTSRH--QEAEMAQNAVRLHYG 490
Query: 576 LPQIARLLQ-SGNSDVVRSGASLLSNMSRHPLLHRVMGNQ-VFPEVTRLL 623
LP + +LL + ++++ L+ N++ P H + Q P + +LL
Sbjct: 491 LPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLL 540
Score = 35.4 bits (80), Expect = 0.19
Identities = 24/69 (34%), Positives = 34/69 (49%)
Query: 277 ESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVS 336
++A +Q G + LV LL S + NV AAG L NL + NK+ + GI V
Sbjct: 390 DAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVR 449
Query: 337 LLRRTGNAE 345
+ R G+ E
Sbjct: 450 TVLRAGDRE 458
Score = 35.0 bits (79), Expect = 0.25
Identities = 48/219 (21%), Positives = 79/219 (36%), Gaps = 30/219 (13%)
Query: 247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306
IP V+ L S + + + E AK V GG+ K+V LL N
Sbjct: 237 IPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI 296
Query: 307 AAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEE 366
L+ L + + +KL G + V+++R + LLW S ++
Sbjct: 297 TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEK-------LLWTTSRVLKVL-S 348
Query: 367 LIADALPVLADRVIIPFSGWCDGNSNMSREVVDP--EVFFNATGCLRNLSSADAGRQTMR 424
+ + P + + G + + DP + N LRNLS A ++ M
Sbjct: 349 VCSSNKPAIVE---------AGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGME 399
Query: 425 NYSGLIDSLMAYVQNCVAASRCDDKSVENCMC-VLHNLS 462
G + L+ DD +V C +L NL+
Sbjct: 400 GLLGTLVQLLG----------SDDINVVTCAAGILSNLT 428
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.128 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,169,873
Number of Sequences: 37866
Number of extensions: 1134456
Number of successful extensions: 3136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2886
Number of HSP's gapped (non-prelim): 147
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.