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Search of human proteins with 52487191
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52487191 thioredoxin domain containing 4 (endoplasmic
reticulum) [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 832 0.0
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 103 2e-22
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 87 4e-17
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 84 2e-16
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 70 3e-12
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 68 2e-11
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 68 2e-11
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 61 2e-09
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 59 1e-08
gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens] 58 2e-08
gi|227430327 calsequestrin 1 [Homo sapiens] 55 1e-07
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 54 3e-07
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 53 6e-07
gi|28372543 protein disulfide isomerase-like, testis expressed [... 52 1e-06
gi|38505222 thioredoxin domain containing 10 [Homo sapiens] 52 1e-06
gi|94421469 disulfide isomerase [Homo sapiens] 51 2e-06
gi|151101292 thioredoxin domain containing 1 [Homo sapiens] 46 7e-05
gi|50592994 thioredoxin [Homo sapiens] 42 0.001
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa... 39 0.011
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi... 39 0.011
gi|54633317 thioredoxin domain containing 11 [Homo sapiens] 37 0.042
gi|95113651 glutaredoxin 3 [Homo sapiens] 36 0.055
gi|237648961 thioredoxin domain containing 16 isoform 2 [Homo sa... 35 0.093
gi|237648959 thioredoxin domain containing 16 isoform 1 [Homo sa... 35 0.093
gi|210031154 zinc finger protein 541 [Homo sapiens] 35 0.16
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap... 34 0.27
gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap... 34 0.27
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 33 0.35
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 33 0.35
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 33 0.35
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 832 bits (2150), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRF 60
MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRF
Sbjct: 1 MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRF 60
Query: 61 SQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMK 120
SQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMK
Sbjct: 61 SQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMK 120
Query: 121 REYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFER 180
REYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFER
Sbjct: 121 REYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFER 180
Query: 181 VANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDK 240
VANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDK
Sbjct: 181 VANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDK 240
Query: 241 CVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHAD 300
CVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHAD
Sbjct: 241 CVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHAD 300
Query: 301 CDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREF 360
CDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREF
Sbjct: 301 CDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREF 360
Query: 361 HHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL 406
HHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL
Sbjct: 361 HHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL 406
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 103 bits (258), Expect = 2e-22
Identities = 62/194 (31%), Positives = 100/194 (51%), Gaps = 8/194 (4%)
Query: 24 FTPVTTEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNEN 83
+TP L EN DE++N+AD+ LV FYA WC + L P +E+A+ + + P
Sbjct: 172 WTPPPEVTLVLTKENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSP--- 228
Query: 84 QVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDP 143
+ A+VD +D+A+R+ +S YPTLK+FR G +Y G R + DY+ +Q P
Sbjct: 229 PIPLAKVDATAETDLAKRFDVSGYPTLKIFRKG--RPYDYNGPREKYGIVDYMIEQSGPP 286
Query: 144 IQEIRDLAEITTL--DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFG-DVSK 200
+EI L ++ D IIG F+ + Y+ ++ AN L +D F F +++K
Sbjct: 287 SKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKFHHTFSTEIAK 346
Query: 201 PERYSGDNIIYKPP 214
+ S ++ P
Sbjct: 347 FLKVSQGQLVVMQP 360
Score = 63.2 bits (152), Expect = 4e-10
Identities = 29/105 (27%), Positives = 58/105 (55%), Gaps = 5/105 (4%)
Query: 34 LDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93
L+ N D + + D L+ FYA WC + P +E+ ++++K++ P + A++D
Sbjct: 67 LNDANFDNFVADKDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDP---PIPVAKIDAT 123
Query: 94 QHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
S +A R+ +S YPT+K+ + G + +Y G R+ + + +R+
Sbjct: 124 SASVLASRFDVSGYPTIKILKKGQAV--DYEGSRTQEEIVAKVRE 166
Score = 40.4 bits (93), Expect = 0.003
Identities = 20/91 (21%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 50 LVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPT 109
L+ FYA WC + L P++ + +++ + +V A++D + + RY++ +PT
Sbjct: 547 LIEFYAPWCGHCKQLEPVYNS----LAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPT 602
Query: 110 LKLFRNGMMMK--REYRGQRSVKALADYIRQ 138
+ +G + G R ++ L+ +I +
Sbjct: 603 IYFAPSGDKKNPVKFEGGDRDLEHLSKFIEE 633
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 86.7 bits (213), Expect = 4e-17
Identities = 85/367 (23%), Positives = 160/367 (43%), Gaps = 19/367 (5%)
Query: 34 LDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93
L N E L LV FYA WC + L P + +A+ +K E +++ A+VD
Sbjct: 29 LRKSNFAEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAE---GSEIRLAKVDAT 85
Query: 94 QHSDIAQRYRISKYPTLKLFRNG-MMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
+ SD+AQ+Y + YPT+K FRNG +EY R + ++++++ + D A
Sbjct: 86 EESDLAQQYGVRGYPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAA 145
Query: 153 ITTL-DRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNII- 210
+L + S+ +IG+F+ +SD+ + F + A + D +++ DV + D ++
Sbjct: 146 AESLVESSEVAVIGFFKDVESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKDGVVL 205
Query: 211 YKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMK 270
+K + + G +T ++ ++I+ +PLV E T + ++ + IL +
Sbjct: 206 FKKFDEGRNN--FEGEVTKENL-LDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLP 262
Query: 271 EDTESLEIFQNEVARQLISEKGTINFLHADCDKF--RHPLLHIQKTPADCPVIAIDSF-R 327
+ + + S KG I F+ D D + L +CP + + +
Sbjct: 263 KSVSDYDGKLSNFKTAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEE 322
Query: 328 HMYVFGDFKDVLIPGKLKQFVFDLHSGKL--HREFHHGPDPTDTAP-----GEQAQDVAS 380
M + + L ++ +F GK+ H P+ D P G+ +DVA
Sbjct: 323 EMTKYKPESEELTAERITEFCHRFLEGKIKPHLMSQELPEDWDKQPVKVLVGKNFEDVAF 382
Query: 381 SPPESSF 387
++ F
Sbjct: 383 DEKKNVF 389
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 51 VNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTL 110
V FYA WC + L PI+ D + E + + +V A++D + + ++ +PTL
Sbjct: 390 VEFYAPWCGHCKQLAPIW----DKLGETYKDHENIVIAKMDSTANE--VEAVKVHSFPTL 443
Query: 111 KLF-RNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEI 153
K F + +Y G+R++ ++ D + DL ++
Sbjct: 444 KFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDL 487
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 84.0 bits (206), Expect = 2e-16
Identities = 87/370 (23%), Positives = 162/370 (43%), Gaps = 33/370 (8%)
Query: 18 LLVTWVFTPVTTEITSLDTENIDEILNN---ADVALVNFYADWCRFSQMLHPIFEEASDV 74
LL+ +++ L +N + +++ A + LV F+A WC + L P +E A+
Sbjct: 14 LLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATR 73
Query: 75 IKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALAD 134
+K P A+VDC +++ +Y +S YPTLK+FR+G Y G R+ +
Sbjct: 74 LKGIVP------LAKVDCTANTNTCNKYGVSGYPTLKIFRDG-EEAGAYDGPRTADGIVS 126
Query: 135 YIRQQKSDPIQEIRDLAEITTLDRSK-RNIIGYFEQKDSDNYRVFERVANILHDDCAFLS 193
++++Q +R E K +I+G+F+ S+ + F + A+ L D+ F
Sbjct: 127 HLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAH 186
Query: 194 AFGDVSKPERY--SGDNIIYKPPGH-----SAPDMVYLGAMTNFDVTYNWIQDKCVPLVR 246
+ S Y +G+ II P H + Y +IQ+ +
Sbjct: 187 TNVE-SLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICP 245
Query: 247 EITFENGEELTEEGLPFLILFH---MKEDTESLEIFQNE---VARQLISEKGTINFLHAD 300
+T +N + + +G LI ++ +++ + ++N VA++ + +NF A
Sbjct: 246 HMTEDNKDLI--QGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVAS 303
Query: 301 CDKFRHPL--LHIQKTPADCPVIAIDSFR-HMYVFGDFKDVLIPGK-LKQFVFDLHSGKL 356
F H L ++ T + PV+AI + + +V + + GK L++F+ D G L
Sbjct: 304 RKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQE--EFSRDGKALERFLQDYFDGNL 361
Query: 357 HREFHHGPDP 366
R P P
Sbjct: 362 KRYLKSEPIP 371
Score = 55.5 bits (132), Expect = 9e-08
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 9/114 (7%)
Query: 37 ENIDEILNNADV-ALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQH 95
EN DEI+NN + L+ FYA WC + L P ++E + + ++ PN +V A++D
Sbjct: 384 ENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKD-PN---IVIAKMDATA- 438
Query: 96 SDIAQRYRISKYPTLKLF-RNGMMMKREYRGQRSVKALADYIRQQKSDP--IQE 146
+D+ Y + +PT+ N + ++Y G R + Y++++ ++P IQE
Sbjct: 439 NDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQE 492
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 70.1 bits (170), Expect = 3e-12
Identities = 45/159 (28%), Positives = 73/159 (45%), Gaps = 5/159 (3%)
Query: 26 PVTTEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQV 85
P I L + L LV FYA WC Q L P + +A+ V+ E V
Sbjct: 39 PKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAE---SMVV 95
Query: 86 VFARVDCDQHSDIAQRYRISKYPTLKLFRNG-MMMKREYRGQRSVKALADYIRQQKSDPI 144
A+VD ++A+ + +++YPTLK FRNG EY G R + +A+++R++
Sbjct: 96 TLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSA 155
Query: 145 QEIRDLAEITTLDRSK-RNIIGYFEQKDSDNYRVFERVA 182
+ D A L + +IG+F+ ++ F +A
Sbjct: 156 MRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALA 194
Score = 39.3 bits (90), Expect = 0.006
Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 12/127 (9%)
Query: 22 WVFTPVTTEI-TSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFP 80
W PV T + + + DE N V FYA WC + + P +E + E++
Sbjct: 385 WDQRPVKTLVGKNFEQVAFDETKN----VFVKFYAPWCTHCKEMAPAWE----ALAEKYQ 436
Query: 81 NENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMK-REYRGQRSVKALADYIRQQ 139
+ ++ A +D + + + +PTLK F G K EY+ R ++ + ++
Sbjct: 437 DHEDIIIAELDATANE--LDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNG 494
Query: 140 KSDPIQE 146
P +E
Sbjct: 495 GVLPTEE 501
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 5/114 (4%)
Query: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
+ +L N D+ + + + FYA WC + L P +EE S K+EFP V A V
Sbjct: 324 VLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELS---KKEFPGLAGVKIAEV 379
Query: 91 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPI 144
DC +I +Y + YPTL LFR G + E+ G R + +L ++ Q D +
Sbjct: 380 DCTAERNICSKYSVRGYPTLLLFRGGKKVS-EHSGGRDLDSLHRFVLSQAKDEL 432
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/88 (35%), Positives = 46/88 (52%), Gaps = 3/88 (3%)
Query: 51 VNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTL 110
V F+A WC Q L P + + D K + +V A+VDC HSD+ + YPTL
Sbjct: 82 VMFFAPWCGHCQRLQPTWNDLGD--KYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTL 139
Query: 111 KLFRNGMMMKREYRGQRSVKALADYIRQ 138
KLF+ G + Y+G R + L +++ Q
Sbjct: 140 KLFKPGQEAVK-YQGPRDFQTLENWMLQ 166
Score = 55.1 bits (131), Expect = 1e-07
Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
Query: 51 VNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTL 110
+ F+A WC + L P +E+ + ++ + V +VDC QH ++ ++ YPTL
Sbjct: 210 IKFFAPWCGHCKALAPTWEQLALGLE----HSETVKIGKVDCTQHYELCSGNQVRGYPTL 265
Query: 111 KLFRNGMMMKREYRGQRSVKALADYIRQQ 139
FR+G + +Y+G+R +++L +Y+ Q
Sbjct: 266 LWFRDGKKVD-QYKGKRDLESLREYVESQ 293
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 67.8 bits (164), Expect = 2e-11
Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 5/114 (4%)
Query: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
+ +L N D+ + + + FYA WC + L P +EE S K+EFP V A V
Sbjct: 216 VLALTENNFDDTIAEG-ITFIKFYAPWCGHCKTLAPTWEELS---KKEFPGLAGVKIAEV 271
Query: 91 DCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPI 144
DC +I +Y + YPTL LFR G + E+ G R + +L ++ Q D +
Sbjct: 272 DCTAERNICSKYSVRGYPTLLLFRGGKKVS-EHSGGRDLDSLHRFVLSQAKDEL 324
Score = 55.1 bits (131), Expect = 1e-07
Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
Query: 51 VNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTL 110
+ F+A WC + L P +E+ + ++ + V +VDC QH ++ ++ YPTL
Sbjct: 102 IKFFAPWCGHCKALAPTWEQLALGLE----HSETVKIGKVDCTQHYELCSGNQVRGYPTL 157
Query: 111 KLFRNGMMMKREYRGQRSVKALADYIRQQ 139
FR+G + +Y+G+R +++L +Y+ Q
Sbjct: 158 LWFRDGKKVD-QYKGKRDLESLREYVESQ 185
Score = 43.1 bits (100), Expect = 4e-04
Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 84 QVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQ 138
+V A+VDC HSD+ + YPTLKLF+ G + Y+G R + L +++ Q
Sbjct: 5 KVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVK-YQGPRDFQTLENWMLQ 58
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 61.2 bits (147), Expect = 2e-09
Identities = 33/122 (27%), Positives = 64/122 (52%), Gaps = 8/122 (6%)
Query: 14 CSLLLLVTWVFTPVTTEITSLDTENID-EILNNADVALVNFYADWCRFSQMLHPIFEEAS 72
C+ L V +++ + ++ L N + E++ + + LV FYA WC Q L P +++A+
Sbjct: 11 CTFFLAVNGLYSS-SDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAA 69
Query: 73 DVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKAL 132
+K+ V VD D+H + +Y + +PT+K+F + +Y+G R+ +A+
Sbjct: 70 TALKDV------VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAI 123
Query: 133 AD 134
D
Sbjct: 124 VD 125
Score = 56.2 bits (134), Expect = 5e-08
Identities = 29/88 (32%), Positives = 51/88 (57%), Gaps = 3/88 (3%)
Query: 30 EITSLDTENIDE-ILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
++ L ++ D+ +L++ DV +V FYA WC + L P + A+ +KE+ + +V A
Sbjct: 161 DVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQ--TKGKVKLA 218
Query: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNG 116
VD + +A RY I +PT+K+F+ G
Sbjct: 219 AVDATVNQVLASRYGIRGFPTIKIFQKG 246
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
Query: 34 LDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93
L E+ D+ + LV F+A WC + + P FE+A++ + E + V A VD
Sbjct: 281 LTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSG--VLAAVDAT 338
Query: 94 QHSDIAQRYRISKYPTLKLFRNG 116
+ +A+R+ IS++PTLK F+NG
Sbjct: 339 VNKALAERFHISEFPTLKYFKNG 361
Score = 53.5 bits (127), Expect = 3e-07
Identities = 32/111 (28%), Positives = 51/111 (45%), Gaps = 7/111 (6%)
Query: 29 TEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFA 88
T + L +N E L LV FYA WC + + P F +D K+ + ++ A
Sbjct: 397 TSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKD----DRKIACA 452
Query: 89 RVDC--DQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIR 137
VDC D++ D+ Q+ + YPT + G ++ Y R+ +YIR
Sbjct: 453 AVDCVKDKNQDLCQQEAVKGYPTFHYYHYGKFAEK-YDSDRTELGFTNYIR 502
Score = 37.0 bits (84), Expect = 0.032
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 6/100 (6%)
Query: 22 WVFTPVTTEITSLDTE-NIDEILNNADVAL-VNFYADWCRFSQMLHPIFEEASDVIKEEF 79
W P ++ LD+E + +L + L + FYA WC + + P F++A+ ++
Sbjct: 144 WEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHA 203
Query: 80 PNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMM 119
V++ + +I + Y + +PT+ F G +
Sbjct: 204 VLAGMNVYS----SEFENIKEEYSVRGFPTICYFEKGRFL 239
>gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
Length = 399
Score = 57.8 bits (138), Expect = 2e-08
Identities = 73/363 (20%), Positives = 150/363 (41%), Gaps = 21/363 (5%)
Query: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIK--EEFPNENQVVFA 88
+ SL +N ++L D+ L +Y + ++ F+ V++ + + F
Sbjct: 34 VVSLSEKNFKQVLKKYDL-LCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVLEHKAIGFV 92
Query: 89 RVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIR 148
VD + + +A++ + +L + + + E+ G+ + L +++ DP++ I
Sbjct: 93 MVDAKKEAKLAKKLGFDEEGSLYILKGDRTI--EFDGEFAADVLVEFLLDLIEDPVEIIS 150
Query: 149 DLAEITTLDRSKRNI--IGYFEQKDSDNYRVFERVANILHDDCAFLSAFG-DVSKPERYS 205
E+ +R + I IG+F+ +DS+ Y+ FE A F + F V+K
Sbjct: 151 SKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATFDKGVAKKLSLK 210
Query: 206 GDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLP--F 263
+ + + P P + T ++ ++++ P +R + E E E+ L
Sbjct: 211 MNEVDFYEPFMDEPIAIPNKPYTEEELV-EFVKEHQRPTLRRLRPEEMFETWEDDLNGIH 269
Query: 264 LILFHMKEDTESLEIFQ--NEVARQLISEKGTINFLHADCDKFRHPLLHIQKT------- 314
++ F K D + E + +VAR ++ ++ L D D F + + +KT
Sbjct: 270 IVAFAEKSDPDGYEFLEILKQVARD-NTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFR 328
Query: 315 PADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQ 374
P V D+ D D+ +L+ ++ D+ SGK++ E D D E+
Sbjct: 329 PQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEE 388
Query: 375 AQD 377
D
Sbjct: 389 DND 391
>gi|227430327 calsequestrin 1 [Homo sapiens]
Length = 396
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/136 (25%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 62 QMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKR 121
+M I E A+ V++++ V F VD ++ + +A++ +++ ++ +F+ ++
Sbjct: 86 EMEELILELAAQVLEDK-----GVGFGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVI-- 138
Query: 122 EYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNI--IGYFEQKDSDNYRVFE 179
EY G+ S + +++ DP++ I E+ + + I IGYF+ KDS++Y+ FE
Sbjct: 139 EYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFE 198
Query: 180 RVANILHDDCAFLSAF 195
A H F + F
Sbjct: 199 DAAEEFHPYIPFFATF 214
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 53.5 bits (127), Expect = 3e-07
Identities = 36/99 (36%), Positives = 53/99 (53%), Gaps = 14/99 (14%)
Query: 25 TPVTTEITSLDTENI-------DEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKE 77
T TT I SL T NI D ++N+ +V+F+A WC ++L P E+ V K+
Sbjct: 51 TIYTTRI-SLTTFNIQDGPDFQDRVVNSETPVVVDFHAQWCGPCKILGPRLEKM--VAKQ 107
Query: 78 EFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG 116
+VV A+VD D H+D+A Y +S PT+ +NG
Sbjct: 108 H----GKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMKNG 142
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 52.8 bits (125), Expect = 6e-07
Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 10/110 (9%)
Query: 27 VTTEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVV 86
V + +T+L +N N+ + LV+F+A WC + L P AS+++ Q+
Sbjct: 451 VNSHVTTLGPQNFPA--NDKEPWLVDFFAPWCPPCRALLPELRRASNLLY------GQLK 502
Query: 87 FARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYI 136
F +DC H + Y I YPT +F + EY G S + + ++I
Sbjct: 503 FGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNI--HEYEGHHSAEQILEFI 550
Score = 48.1 bits (113), Expect = 1e-05
Identities = 28/118 (23%), Positives = 55/118 (46%), Gaps = 7/118 (5%)
Query: 30 EITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFAR 89
EI +L+ D +N+ ++ VNFY+ C L P + + + + + +
Sbjct: 130 EIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEV------DGLLRIGA 183
Query: 90 VDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEI 147
V+C + + ++ YP+L +FR+GM + Y G RS ++L + Q + E+
Sbjct: 184 VNCGDDRMLCRMKGVNSYPSLFIFRSGMAPVK-YHGDRSKESLVSFAMQHVRSTVTEL 240
Score = 45.4 bits (106), Expect = 9e-05
Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 40 DEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIA 99
+++L + +++FYA WC Q P FE + +IK +V +VDC ++
Sbjct: 682 EKVLQGKNHWVIDFYAPWCGPCQNFAPEFELLARMIK------GKVKAGKVDCQAYAQTC 735
Query: 100 QRYRISKYPTLKLF---RNGMMMKREYRGQRSVKALADYIRQQ 139
Q+ I YPT+K + R + E R KA+A I ++
Sbjct: 736 QKAGIRAYPTVKFYFYERAKRNFQEEQINTRDAKAIAALISEK 778
Score = 36.2 bits (82), Expect = 0.055
Identities = 18/86 (20%), Positives = 39/86 (45%), Gaps = 9/86 (10%)
Query: 31 ITSLDTENIDEILNNA---DVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVF 87
+ SL +E++ +V +V+FY+ WC Q+L P ++ + + +
Sbjct: 558 VVSLTPTTFNELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMARTL------TGLINV 611
Query: 88 ARVDCDQHSDIAQRYRISKYPTLKLF 113
+DC Q+ + + +YP ++ F
Sbjct: 612 GSIDCQQYHSFCAQENVQRYPEIRFF 637
>gi|28372543 protein disulfide isomerase-like, testis expressed
[Homo sapiens]
Length = 584
Score = 52.0 bits (123), Expect = 1e-06
Identities = 27/103 (26%), Positives = 54/103 (52%), Gaps = 6/103 (5%)
Query: 51 VNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTL 110
V FYA W + +ML P+ EE + ++ N + ++ A++D + DI Y + +YP
Sbjct: 410 VMFYAPWSKKCKMLFPLLEE----LGRKYQNHSTIIIAKIDVTAN-DIQLMY-LDRYPFF 463
Query: 111 KLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEI 153
+LF +G Y+G+ ++K +D++ I++ +L +
Sbjct: 464 RLFPSGSQQAVLYKGEHTLKGFSDFLESHIKTKIEDEDELLSV 506
Score = 42.7 bits (99), Expect = 6e-04
Identities = 59/294 (20%), Positives = 114/294 (38%), Gaps = 7/294 (2%)
Query: 34 LDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93
L + ++LN +V F+ + S+ L EE ++ +N + F +VD
Sbjct: 48 LTPAGLTQMLNQTRFLMVLFHNPSSKQSRNLA---EELGKAVEIMGKGKNGIGFGKVDIT 104
Query: 94 QHSDIAQRYRISKYPTLKLFRNGMMMKR-EYRGQRSVKALADYIRQQKSDPIQEIRDLAE 152
++ Q + I+K P LKLF G + +G AL ++R+Q S +
Sbjct: 105 IEKELQQEFGITKAPELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQ 164
Query: 153 ITTLDRSK-RNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIY 211
+ S+ I+G+F+ + + +F V + + G+V + D+++
Sbjct: 165 VAEFVISRPLVIVGFFQDLEEEVAELFYDVIKDFPELTFGVITIGNVIGRFHVTLDSVLV 224
Query: 212 KPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKE 271
G + TN I+ V E EN + ++E + +L + +
Sbjct: 225 FKKGKIVNRQKLINDSTNKQELNRVIKQHLTDFVIEYNTENKDLISELHIMSHMLLFVSK 284
Query: 272 DTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLL--HIQKTPADCPVIAI 323
+ES I + I F+ D D+ R+ + + + T D P + I
Sbjct: 285 SSESYGIIIQHYKLASKEFQNKILFILVDADEPRNGRVFKYFRVTEVDIPSVQI 338
>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
Length = 454
Score = 51.6 bits (122), Expect = 1e-06
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 8/102 (7%)
Query: 37 ENIDEILN---NADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93
E++DE N D+ LV+FYA WC + L PI+ E +K + V ++D
Sbjct: 29 EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKS---IGSPVKVGKMDAT 85
Query: 94 QHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADY 135
+S IA + + YPT+KL + + YRG R+ + ++
Sbjct: 86 SYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEF 125
>gi|94421469 disulfide isomerase [Homo sapiens]
Length = 360
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/96 (32%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 44 NNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYR 103
N +D LV FY WCRFS L P F + FP + F +D QHS ++ R+
Sbjct: 206 NGSDCTLVLFYTPWCRFSASLAPHFNS----LPRAFP---ALHFLALDASQHSSLSTRFG 258
Query: 104 ISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQ 139
P + LF+ M R R+++ L +I Q
Sbjct: 259 TVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQ 294
>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
Length = 280
Score = 45.8 bits (107), Expect = 7e-05
Identities = 39/151 (25%), Positives = 74/151 (49%), Gaps = 17/151 (11%)
Query: 1 MHPAVFLSLPDLRCSLLLLVTWVFTPVT----TEITSLDTENIDEILNNADVALVNFYAD 56
M P+ L++P ++L+L+ W P T + + + EN E+L ++ FYA
Sbjct: 1 MAPSGSLAVP---LAVLVLLLWG-APWTHGRRSNVRVITDENWRELLEGD--WMIEFYAP 54
Query: 57 WCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG 116
WC Q L P +E + E+ + +V A+VD + ++ R+ I+ PT+ ++G
Sbjct: 55 WCPACQNLQPEWESFA-----EWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDG 109
Query: 117 MMMKREYRGQRSVKALADYIRQQKSDPIQEI 147
R Y+G R+ K ++I ++ I+ +
Sbjct: 110 EF--RRYQGPRTKKDFINFISDKEWKSIEPV 138
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 8/83 (9%)
Query: 48 VALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKY 107
+ +V+F A WC +M+ P F S E++ N V+F VD D D+A +
Sbjct: 22 LVVVDFSATWCGPCKMIKPFFHSLS----EKYSN---VIFLEVDVDDCQDVASECEVKCM 74
Query: 108 PTLKLFRNGMMMKREYRGQRSVK 130
PT + F+ G + E+ G K
Sbjct: 75 PTFQFFKKGQKV-GEFSGANKEK 96
>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
sapiens]
Length = 258
Score = 38.5 bits (88), Expect = 0.011
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 11/90 (12%)
Query: 50 LVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRIS---- 105
+V F+A+W Q PI+ + S +K N F +VD +++D++ RY++S
Sbjct: 121 IVEFFANWSNDCQSFAPIYADLS--LKYNCTGLN---FGKVDVGRYTDVSTRYKVSTSPL 175
Query: 106 --KYPTLKLFRNGMMMKREYRGQRSVKALA 133
+ PTL LF+ G R + + +A++
Sbjct: 176 TKQLPTLILFQGGKEAMRRPQIDKKGRAVS 205
>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
sapiens]
Length = 296
Score = 38.5 bits (88), Expect = 0.011
Identities = 25/90 (27%), Positives = 46/90 (51%), Gaps = 11/90 (12%)
Query: 50 LVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRIS---- 105
+V F+A+W Q PI+ + S +K N F +VD +++D++ RY++S
Sbjct: 159 IVEFFANWSNDCQSFAPIYADLS--LKYNCTGLN---FGKVDVGRYTDVSTRYKVSTSPL 213
Query: 106 --KYPTLKLFRNGMMMKREYRGQRSVKALA 133
+ PTL LF+ G R + + +A++
Sbjct: 214 TKQLPTLILFQGGKEAMRRPQIDKKGRAVS 243
>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
Length = 958
Score = 36.6 bits (83), Expect = 0.042
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 31 ITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARV 90
IT + T+ E++ L+ +YA WC F L+ IF + + P + V AR+
Sbjct: 665 ITEVTTDTFWEVVLQKQDVLLLYYAPWCGFCPSLNHIFIQ----LARNLPMDTFTV-ARI 719
Query: 91 DCDQHSDIAQRYRISKYPTLKLF 113
D Q +D+ + + + PT+ F
Sbjct: 720 DVSQ-NDLPWEFMVDRLPTVLFF 741
Score = 36.2 bits (82), Expect = 0.055
Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 42 ILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQR 101
+ +++V L+ FYA WC S E+A+ + + QV+F ++C + ++
Sbjct: 121 VRRDSEVVLLFFYAPWCGQSIAARAEIEQAASRLSD------QVLFVAINCWWNQGKCRK 174
Query: 102 YR-ISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITT-LDRS 159
+ +P + L+ EY+G S + ++R+ P+ I +E+ L
Sbjct: 175 QKHFFYFPVIYLYHRS-FGPIEYKGPMSAVYIEKFVRRVMK-PLLYIPSQSELLDFLSNY 232
Query: 160 KRNIIGYFE 168
+ ++GYFE
Sbjct: 233 EPGVLGYFE 241
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 36.2 bits (82), Expect = 0.055
Identities = 19/79 (24%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Query: 43 LNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRY 102
L + +V+F+A W ++ + E + +E P QV F +++ + +++++Y
Sbjct: 28 LKAKSLLVVHFWAPWAPQCAQMNEVMAE----LAKELP---QVSFVKLEAEGVPEVSEKY 80
Query: 103 RISKYPTLKLFRNGMMMKR 121
IS PT F+N + R
Sbjct: 81 EISSVPTFLFFKNSQKIDR 99
>gi|237648961 thioredoxin domain containing 16 isoform 2 [Homo
sapiens]
Length = 820
Score = 35.4 bits (80), Expect = 0.093
Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 30 EITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFAR 89
E+T TE A ++V FYA W Q + F ++ + + + ++ R
Sbjct: 386 ELTVELTEETFNATVMASDSIVLFYAGW----QAVSMAFLQSYIDVAVKLKGTSTMLLTR 441
Query: 90 VDCDQHSDIAQRYRISKYPTLKLFRNG 116
++C SD+ + ++++P +K+++ G
Sbjct: 442 INCADWSDVCTKQNVTEFPIIKMYKKG 468
>gi|237648959 thioredoxin domain containing 16 isoform 1 [Homo
sapiens]
Length = 825
Score = 35.4 bits (80), Expect = 0.093
Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 30 EITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFAR 89
E+T TE A ++V FYA W Q + F ++ + + + ++ R
Sbjct: 391 ELTVELTEETFNATVMASDSIVLFYAGW----QAVSMAFLQSYIDVAVKLKGTSTMLLTR 446
Query: 90 VDCDQHSDIAQRYRISKYPTLKLFRNG 116
++C SD+ + ++++P +K+++ G
Sbjct: 447 INCADWSDVCTKQNVTEFPIIKMYKKG 473
>gi|210031154 zinc finger protein 541 [Homo sapiens]
Length = 1365
Score = 34.7 bits (78), Expect = 0.16
Identities = 37/122 (30%), Positives = 49/122 (40%), Gaps = 23/122 (18%)
Query: 305 RHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVF----------DLHSG 354
+H L H Q+ C + + R ++ G +L K K FV D S
Sbjct: 157 KHYLTHSQERKHVCKICSKAFKRQDHLTGH---MLTHQKTKPFVCIEQGCSKSYCDYRSL 213
Query: 355 KLHREFHHGPDPTDTAPGEQ--------AQDVASSPPESSFQKLAPSEYRY--TLLRDRD 404
+ H E HHG AP E+ A + A PP SS + L P E R +LL RD
Sbjct: 214 RRHYEVHHGLCILKEAPPEEEACGDSPHAHESAGQPPPSSLRSLVPPEARSPGSLLPHRD 273
Query: 405 EL 406
L
Sbjct: 274 LL 275
>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
sapiens]
Length = 604
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 21/117 (17%)
Query: 15 SLLLLVTWV--------------FTPVTTEITSLDTENI-DEILNNADVALVNFYADWCR 59
SLLLL+ W+ ++P + +T L + + +L + V F+A WC
Sbjct: 13 SLLLLLLWLLAVPGANAAPRSALYSP-SDPLTLLQADTVRGAVLGSRSAWAVEFFASWCG 71
Query: 60 FSQMLHPIFEEASDVIKEEFPNENQVVFARVDC--DQHSDIAQRYRISKYPTLKLFR 114
P ++ ++ +K P + A +DC + +S + + + I +PT++ F+
Sbjct: 72 HCIAFAPTWKALAEDVKAWRP---ALYLAALDCAEETNSAVCRDFNIPGFPTVRFFK 125
>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
sapiens]
Length = 747
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 21/117 (17%)
Query: 15 SLLLLVTWV--------------FTPVTTEITSLDTENI-DEILNNADVALVNFYADWCR 59
SLLLL+ W+ ++P + +T L + + +L + V F+A WC
Sbjct: 13 SLLLLLLWLLAVPGANAAPRSALYSP-SDPLTLLQADTVRGAVLGSRSAWAVEFFASWCG 71
Query: 60 FSQMLHPIFEEASDVIKEEFPNENQVVFARVDC--DQHSDIAQRYRISKYPTLKLFR 114
P ++ ++ +K P + A +DC + +S + + + I +PT++ F+
Sbjct: 72 HCIAFAPTWKALAEDVKAWRP---ALYLAALDCAEETNSAVCRDFNIPGFPTVRFFK 125
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 33.5 bits (75), Expect = 0.35
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%)
Query: 34 LDTENIDEILNNADVALV--NFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVD 91
L E+ + L A LV +F A WC + + P F S +K E VVF VD
Sbjct: 387 LSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALS--VKHE-----DVVFLEVD 439
Query: 92 CDQHSDIAQRYRISKYPTLKLFR 114
D ++ + I PT + ++
Sbjct: 440 ADNCEEVVRECAIMCVPTFQFYK 462
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 33.5 bits (75), Expect = 0.35
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%)
Query: 34 LDTENIDEILNNADVALV--NFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVD 91
L E+ + L A LV +F A WC + + P F S +K E VVF VD
Sbjct: 454 LSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALS--VKHE-----DVVFLEVD 506
Query: 92 CDQHSDIAQRYRISKYPTLKLFR 114
D ++ + I PT + ++
Sbjct: 507 ADNCEEVVRECAIMCVPTFQFYK 529
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 33.5 bits (75), Expect = 0.35
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 9/83 (10%)
Query: 34 LDTENIDEILNNADVALV--NFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVD 91
L E+ + L A LV +F A WC + + P F S +K E VVF VD
Sbjct: 387 LSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALS--VKHE-----DVVFLEVD 439
Query: 92 CDQHSDIAQRYRISKYPTLKLFR 114
D ++ + I PT + ++
Sbjct: 440 ADNCEEVVRECAIMCVPTFQFYK 462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,945,232
Number of Sequences: 37866
Number of extensions: 723837
Number of successful extensions: 1804
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1728
Number of HSP's gapped (non-prelim): 62
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.