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Search of human proteins with 52426748
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens] 961 0.0
gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|54792105 cholinergic receptor, muscarinic 2 [Homo sapiens] 523 e-148
gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens] 414 e-115
gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens] 400 e-111
gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens] 291 9e-79
gi|194018562 histamine receptor H3 [Homo sapiens] 193 3e-49
gi|149158709 histamine receptor H1 [Homo sapiens] 185 7e-47
gi|149158706 histamine receptor H1 [Homo sapiens] 185 7e-47
gi|149158704 histamine receptor H1 [Homo sapiens] 185 7e-47
gi|4504491 histamine receptor H1 [Homo sapiens] 185 7e-47
gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo sa... 171 2e-42
gi|17986270 dopamine receptor D2 isoform short [Homo sapiens] 164 1e-40
gi|4503385 dopamine receptor D2 isoform long [Homo sapiens] 159 4e-39
gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens] 149 7e-36
gi|32483397 dopamine receptor D4 [Homo sapiens] 144 2e-34
gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens] 141 1e-33
gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens] 139 6e-33
gi|89191861 dopamine receptor D3 isoform a [Homo sapiens] 137 3e-32
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 130 3e-30
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 128 1e-29
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 128 1e-29
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 127 2e-29
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 127 2e-29
>gi|52426748 cholinergic receptor, muscarinic 4 [Homo sapiens]
Length = 479
Score = 961 bits (2485), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN 60
MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN
Sbjct: 1 MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVN 60
Query: 61 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV 120
RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV
Sbjct: 61 RQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASV 120
Query: 121 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV 180
MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV
Sbjct: 121 MNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTV 180
Query: 181 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK 240
PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK
Sbjct: 181 PDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAK 240
Query: 241 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS 300
TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS
Sbjct: 241 TLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGS 300
Query: 301 ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV 360
ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV
Sbjct: 301 ATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIV 360
Query: 361 PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV 420
PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
Sbjct: 361 PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV 420
Query: 421 LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
Sbjct: 421 LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
>gi|4502817 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792117 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792115 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792113 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792111 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792109 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792107 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|54792105 cholinergic receptor, muscarinic 2 [Homo sapiens]
Length = 466
Score = 523 bits (1347), Expect = e-148
Identities = 277/474 (58%), Positives = 343/474 (72%), Gaps = 26/474 (5%)
Query: 20 TSSSHNR------YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFS 73
T+SS+N Y+T E+VFI V GSLSLVT++GNILVM+SIKVNR LQTVNNYFLFS
Sbjct: 5 TNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFS 64
Query: 74 LACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFC 133
LACADLIIG FSMNLYT+Y + GYWPLG VVCDLWLALDYVVSNASVMNLLIISFDRYFC
Sbjct: 65 LACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFC 124
Query: 134 VTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNP 193
VTKPLTYP +RTTKMAG+MIAAAWVLSF+LWAPAILFWQF+VG RTV D +C+IQF SN
Sbjct: 125 VTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNA 184
Query: 194 AVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
AVTFGTAIAAFYLPV+IMTVLY HIS AS+SR+ K + E + + + ++ ++K +
Sbjct: 185 AVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPN 244
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV--ADKDTSNESSSGSA-TQNTKERPA 310
P + + L + K++ P P V +K++SN+S+S SA N ++
Sbjct: 245 NNNMPSSD---DGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEI 301
Query: 311 TELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECV----TAIEIVPATPAG 366
T+ T +T+ + + S+ + I+I TK ++ T +E+V ++
Sbjct: 302 TQDENTVSTSLG--------HSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQN 353
Query: 367 MRPAAN-VARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTF 425
N VARK + + Q KK+ +RE+KVTRTI AILLAFI+TW PYNVMVL+NTF
Sbjct: 354 GDEKQNIVARKIVKMTK-QPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTF 412
Query: 426 CQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
C CIP+TVW+IGYWLCY+NSTINPACYALCNATFKKTF+HLL+C Y+NIG R
Sbjct: 413 CAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR 466
>gi|7108336 cholinergic receptor, muscarinic 5 [Homo sapiens]
Length = 532
Score = 414 bits (1063), Expect = e-115
Identities = 233/519 (44%), Positives = 308/519 (59%), Gaps = 59/519 (11%)
Query: 3 NFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQ 62
N T VNG+ N R+ E++ IA VT +SL+T+VGN+LVM+S KVN Q
Sbjct: 8 NATTVNGTPVNHQPL-------ERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ 60
Query: 63 LQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMN 122
L+TVNNY+L SLACADLIIG FSMNLYT YI+ G W LG++ CDLWLALDYV SNASVMN
Sbjct: 61 LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN 120
Query: 123 LLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPD 182
LL+ISFDRYF +T+PLTY A+RT K AG+MI AW++SF+LWAPAIL WQ++VGKRTVP
Sbjct: 121 LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL 180
Query: 183 NQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLY--IHISLASRSRVHKHRPEGPKEKKAK 240
++C IQFLS P +TFGTAIAAFY+PV +MT+LY I+ R++ KA+
Sbjct: 181 DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE 240
Query: 241 TLAFLKSPLMKQSVKKPPPGEAAREELR------------NGKLEEAPPPAL-------- 280
L + ++ P P A RE + GK +A P+
Sbjct: 241 KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL 300
Query: 281 -------------PPPPRPVAD-------KDTSNESSSGSATQNTKERPATELSTTEATT 320
P PV K++ E S T+ T + TE S +
Sbjct: 301 TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN 360
Query: 321 PAM-PAPPLQPRALNPASRWSKIQIVTKQTGNECVT----AIEIVPAT-PAGMRPAANVA 374
+ PA +P++ + K ++V K GN+ ++I+P P P+
Sbjct: 361 YLLSPAAAHRPKSQKCVA--YKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGL 418
Query: 375 RKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTV 434
S ++KR + +ERK +T+ AILLAFI+TWTPYN+MVLV+TFC C+P T+
Sbjct: 419 NPNPS--HQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTL 476
Query: 435 WSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR 473
W +GYWLCYVNST+NP CYALCN TF+KTF+ LLLC+++
Sbjct: 477 WHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWK 515
>gi|37622910 cholinergic receptor, muscarinic 1 [Homo sapiens]
Length = 460
Score = 400 bits (1027), Expect = e-111
Identities = 216/448 (48%), Positives = 283/448 (63%), Gaps = 40/448 (8%)
Query: 31 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 90
++ FI TG LSL TV GN+LV++S KVN +L+TVNNYFL SLACADLIIG FSMNLYT
Sbjct: 24 QVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYT 83
Query: 91 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 150
Y++ G+W LG + CDLWLALDYV SNASVMNLL+ISFDRYF VT+PL+Y A+RT + A
Sbjct: 84 TYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAA 143
Query: 151 LMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVI 210
LMI AW++SFVLWAPAILFWQ++VG+RTV QC+IQFLS P +TFGTA+AAFYLPV +
Sbjct: 144 LMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTV 203
Query: 211 MTVLYIHISLASRSRVHK----HRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREE 266
M LY I + +R + E P + + + +S + + PPG R
Sbjct: 204 MCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCR-C 262
Query: 267 LRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATE-LSTTEATTPAMPA 325
R +L +A +++ +E S S T + E P +E + P A
Sbjct: 263 CRAPRLLQA---------YSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQA 313
Query: 326 PPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQV 385
P QP P S + ++ TK+ + G +P + Q+
Sbjct: 314 PTKQP----PRSSPNTVKRPTKKGRDR----------AGKGQKPR----------GKEQL 349
Query: 386 RKKRQMA-ARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYV 444
K++ + +E+K RT+ AILLAFILTWTPYN+MVLV+TFC+ C+P+T+W +GYWLCYV
Sbjct: 350 AKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYV 409
Query: 445 NSTINPACYALCNATFKKTFRHLLLCQY 472
NSTINP CYALCN F+ TFR LLLC++
Sbjct: 410 NSTINPMCYALCNKAFRDTFRLLLLCRW 437
>gi|4502819 cholinergic receptor, muscarinic 3 [Homo sapiens]
Length = 590
Score = 291 bits (745), Expect = 9e-79
Identities = 144/217 (66%), Positives = 173/217 (79%), Gaps = 13/217 (5%)
Query: 31 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 90
++VFIA +TG L+LVT++GNILV++S KVN+QL+TVNNYFL SLACADLIIG SMNL+T
Sbjct: 67 QVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFT 126
Query: 91 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 150
YII W LG + CDLWLA+DYV SNASVMNLL+ISFDRYF +T+PLTY A+RTTK AG
Sbjct: 127 TYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAG 186
Query: 151 LMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVI 210
+MI AWV+SFVLWAPAILFWQ+ VGKRTVP +CFIQFLS P +TFGTAIAAFY+PV I
Sbjct: 187 VMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTI 246
Query: 211 MTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKS 247
MT+LY R++K EK+ K LA L++
Sbjct: 247 MTILY--------WRIYKE-----TEKRTKELAGLQA 270
Score = 150 bits (380), Expect = 2e-36
Identities = 64/102 (62%), Positives = 85/102 (83%), Gaps = 1/102 (0%)
Query: 371 ANVARKFASIARNQVRKKRQMA-ARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSC 429
A +A++FA R+Q+ K+++M+ +E+K +T+ AILLAFI+TWTPYN+MVLVNTFC SC
Sbjct: 461 ATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSC 520
Query: 430 IPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQ 471
IP T W++GYWLCY+NST+NP CYALCN TF+ TF+ LLLCQ
Sbjct: 521 IPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQ 562
>gi|194018562 histamine receptor H3 [Homo sapiens]
Length = 445
Score = 193 bits (490), Expect = 3e-49
Identities = 124/470 (26%), Positives = 227/470 (48%), Gaps = 52/470 (11%)
Query: 6 PVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQT 65
P+N +SG + + + +A + L + TV+GN LVML+ + L+T
Sbjct: 9 PLN-ASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRT 67
Query: 66 VNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLI 125
NN+FL +LA +D ++GAF + LY Y++ G W G +C LWL +DY++ +S N+++
Sbjct: 68 QNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVL 127
Query: 126 ISFDRYFCVTKPLTYPARR-TTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQ 184
IS+DR+ VT+ ++Y A++ T+ A + WVL+F+L+ PAIL W+++ G ++P+
Sbjct: 128 ISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGH 187
Query: 185 CFIQFLSNPAVTFGTAIAAFYLPVVIMTV--LYIHISLASRSRVHKHRPEGPKEKKAKTL 242
C+ +F N + F+ P + +T L I++++ R+R+ R +G +E
Sbjct: 188 CYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRL---RLDGARE-----A 239
Query: 243 AFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSAT 302
A + P Q PPPG + +G EA P + + G
Sbjct: 240 AGPEPPPEAQPSPPPPPGCWGCWQKGHG---EAMPLHRYGVGEAAVGAEAGEATLGGGGG 296
Query: 303 QNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPA 362
+ P + ++ T +PR+L S+ S
Sbjct: 297 GGSVASPTSSSGSSSRGTE-------RPRSLKRGSKPS---------------------- 327
Query: 363 TPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLV 422
+A++ ++ ++++ ++ R +R+RKV +++ I+ F L W PY +++++
Sbjct: 328 -----ASSASLEKRMKMVSQSFTQRFR--LSRDRKVAKSLAVIVSIFGLCWAPYTLLMII 380
Query: 423 NTFCQS-CIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQ 471
C C+PD + +WL + NS +NP Y LC+ +F++ F LL Q
Sbjct: 381 RAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQ 430
>gi|149158709 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (470), Expect = 7e-47
Identities = 140/470 (29%), Positives = 215/470 (45%), Gaps = 44/470 (9%)
Query: 31 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 90
+++ + V ++ LVTV N+LV+ +++ R+L TV N ++ SL+ ADLI+GA M +
Sbjct: 26 QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNI 85
Query: 91 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 150
+Y++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL Y RT A
Sbjct: 86 LYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRAS 145
Query: 151 LMIAAAWVLSFVLWAPAILFWQFVVGKRTV-PDNQCFIQFLSNPAVTFGTAIAAFYLPVV 209
I AW LSF LW IL W + + +V +++C F TAI FYLP +
Sbjct: 146 ATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTL 204
Query: 210 IMTVLY----------------IHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
+M Y I+ SL S S + K RPE PK K ++K+
Sbjct: 205 LMLWFYAKIYKAVRQHCQHRELINRSLPSFSEI-KLRPENPKGDAKKPGKESPWEVLKRK 263
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV-------ADKDTSNESSSGSATQNTK 306
K G + + K ++P R V D ++ GS+
Sbjct: 264 PKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVA 323
Query: 307 -ERPATELSTTEATTPAMPAPPL-QPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATP 364
R +L T E A + + + L + +S+ + T E P
Sbjct: 324 VNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR---------TDSDTTTETAPG-K 373
Query: 365 AGMRPAANVARKFASIARNQVRK-KRQMAA-----RERKVTRTIFAILLAFILTWTPYNV 418
+R +N + ++R RQ + RERK + + I+ AFIL W PY +
Sbjct: 374 GKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFI 433
Query: 419 MVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLL 468
+V FC++C + + WL Y+NST+NP Y LCN FKKTF+ +L
Sbjct: 434 FFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|149158706 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (470), Expect = 7e-47
Identities = 140/470 (29%), Positives = 215/470 (45%), Gaps = 44/470 (9%)
Query: 31 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 90
+++ + V ++ LVTV N+LV+ +++ R+L TV N ++ SL+ ADLI+GA M +
Sbjct: 26 QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNI 85
Query: 91 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 150
+Y++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL Y RT A
Sbjct: 86 LYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRAS 145
Query: 151 LMIAAAWVLSFVLWAPAILFWQFVVGKRTV-PDNQCFIQFLSNPAVTFGTAIAAFYLPVV 209
I AW LSF LW IL W + + +V +++C F TAI FYLP +
Sbjct: 146 ATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTL 204
Query: 210 IMTVLY----------------IHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
+M Y I+ SL S S + K RPE PK K ++K+
Sbjct: 205 LMLWFYAKIYKAVRQHCQHRELINRSLPSFSEI-KLRPENPKGDAKKPGKESPWEVLKRK 263
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV-------ADKDTSNESSSGSATQNTK 306
K G + + K ++P R V D ++ GS+
Sbjct: 264 PKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVA 323
Query: 307 -ERPATELSTTEATTPAMPAPPL-QPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATP 364
R +L T E A + + + L + +S+ + T E P
Sbjct: 324 VNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR---------TDSDTTTETAPG-K 373
Query: 365 AGMRPAANVARKFASIARNQVRK-KRQMAA-----RERKVTRTIFAILLAFILTWTPYNV 418
+R +N + ++R RQ + RERK + + I+ AFIL W PY +
Sbjct: 374 GKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFI 433
Query: 419 MVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLL 468
+V FC++C + + WL Y+NST+NP Y LCN FKKTF+ +L
Sbjct: 434 FFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|149158704 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (470), Expect = 7e-47
Identities = 140/470 (29%), Positives = 215/470 (45%), Gaps = 44/470 (9%)
Query: 31 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 90
+++ + V ++ LVTV N+LV+ +++ R+L TV N ++ SL+ ADLI+GA M +
Sbjct: 26 QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNI 85
Query: 91 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 150
+Y++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL Y RT A
Sbjct: 86 LYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRAS 145
Query: 151 LMIAAAWVLSFVLWAPAILFWQFVVGKRTV-PDNQCFIQFLSNPAVTFGTAIAAFYLPVV 209
I AW LSF LW IL W + + +V +++C F TAI FYLP +
Sbjct: 146 ATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTL 204
Query: 210 IMTVLY----------------IHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
+M Y I+ SL S S + K RPE PK K ++K+
Sbjct: 205 LMLWFYAKIYKAVRQHCQHRELINRSLPSFSEI-KLRPENPKGDAKKPGKESPWEVLKRK 263
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV-------ADKDTSNESSSGSATQNTK 306
K G + + K ++P R V D ++ GS+
Sbjct: 264 PKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVA 323
Query: 307 -ERPATELSTTEATTPAMPAPPL-QPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATP 364
R +L T E A + + + L + +S+ + T E P
Sbjct: 324 VNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR---------TDSDTTTETAPG-K 373
Query: 365 AGMRPAANVARKFASIARNQVRK-KRQMAA-----RERKVTRTIFAILLAFILTWTPYNV 418
+R +N + ++R RQ + RERK + + I+ AFIL W PY +
Sbjct: 374 GKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFI 433
Query: 419 MVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLL 468
+V FC++C + + WL Y+NST+NP Y LCN FKKTF+ +L
Sbjct: 434 FFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|4504491 histamine receptor H1 [Homo sapiens]
Length = 487
Score = 185 bits (470), Expect = 7e-47
Identities = 140/470 (29%), Positives = 215/470 (45%), Gaps = 44/470 (9%)
Query: 31 EMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYT 90
+++ + V ++ LVTV N+LV+ +++ R+L TV N ++ SL+ ADLI+GA M +
Sbjct: 26 QLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNI 85
Query: 91 VYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAG 150
+Y++ W LG +C WL++DYV S AS+ ++ I+ DRY V +PL Y RT A
Sbjct: 86 LYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRAS 145
Query: 151 LMIAAAWVLSFVLWAPAILFWQFVVGKRTV-PDNQCFIQFLSNPAVTFGTAIAAFYLPVV 209
I AW LSF LW IL W + + +V +++C F TAI FYLP +
Sbjct: 146 ATILGAWFLSF-LWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTL 204
Query: 210 IMTVLY----------------IHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQS 253
+M Y I+ SL S S + K RPE PK K ++K+
Sbjct: 205 LMLWFYAKIYKAVRQHCQHRELINRSLPSFSEI-KLRPENPKGDAKKPGKESPWEVLKRK 263
Query: 254 VKKPPPGEAAREELRNGKLEEAPPPALPPPPRPV-------ADKDTSNESSSGSATQNTK 306
K G + + K ++P R V D ++ GS+
Sbjct: 264 PKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVA 323
Query: 307 -ERPATELSTTEATTPAMPAPPL-QPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATP 364
R +L T E A + + + L + +S+ + T E P
Sbjct: 324 VNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR---------TDSDTTTETAPG-K 373
Query: 365 AGMRPAANVARKFASIARNQVRK-KRQMAA-----RERKVTRTIFAILLAFILTWTPYNV 418
+R +N + ++R RQ + RERK + + I+ AFIL W PY +
Sbjct: 374 GKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFI 433
Query: 419 MVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLL 468
+V FC++C + + WL Y+NST+NP Y LCN FKKTF+ +L
Sbjct: 434 FFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRIL 483
>gi|55956923 5-hydroxytryptamine (serotonin) receptor 1A [Homo
sapiens]
Length = 422
Score = 171 bits (432), Expect = 2e-42
Identities = 126/443 (28%), Positives = 204/443 (46%), Gaps = 63/443 (14%)
Query: 33 VFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVY 92
V + + G+L V+GN V+ +I + R LQ V NY + SLA DL++ + + +Y
Sbjct: 37 VITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALY 96
Query: 93 IIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLM 152
+ W LG V CDL++ALD + +S+++L I+ DRY+ +T P+ Y +RT + A +
Sbjct: 97 QVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAAL 156
Query: 153 IAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMT 212
I+ W++ F++ P +L W+ R+ PD C I + T + AFY+P+++M
Sbjct: 157 ISLTWLIGFLISIPPMLGWR-TPEDRSDPD-ACTIS--KDHGYTIYSTFGAFYIPLLLML 212
Query: 213 VLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKL 272
VLY I A+R R+ K +VKK E + R+G
Sbjct: 213 VLYGRIFRAARFRIRK------------------------TVKKV---EKTGADTRHG-- 243
Query: 273 EEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELSTTEATTPAMPAPPLQPRA 332
P P K + ES S + + + L A L+
Sbjct: 244 ---------ASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALE--- 291
Query: 333 LNPASRWSKIQIVTKQTGNECVTAIEIVP-ATPAGMRPAANVARKFASIARNQVRKKRQM 391
I + GN + E +P + AG P A + + + RN K++
Sbjct: 292 ----------VIEVHRVGN----SKEHLPLPSEAGPTPCAPASFERKN-ERNAEAKRKMA 336
Query: 392 AARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSC--IPDTVWSIGYWLCYVNSTIN 449
ARERK +T+ I+ FIL W P+ ++ LV FC+S +P + +I WL Y NS +N
Sbjct: 337 LARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLN 396
Query: 450 PACYALCNATFKKTFRHLLLCQY 472
P YA N F+ F+ ++ C++
Sbjct: 397 PVIYAYFNKDFQNAFKKIIKCKF 419
>gi|17986270 dopamine receptor D2 isoform short [Homo sapiens]
Length = 414
Score = 164 bits (416), Expect = 1e-40
Identities = 125/474 (26%), Positives = 199/474 (41%), Gaps = 89/474 (18%)
Query: 6 PVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQT 65
P NGS G +N Y T+ + IA + V GN+LV +++ + LQT
Sbjct: 21 PFNGSDGKAD-----RPHYNYYATLLTLLIAVI--------VFGNVLVCMAVSREKALQT 67
Query: 66 VNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLI 125
NY + SLA ADL++ M + G W + CD+++ LD ++ AS++NL
Sbjct: 68 TTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCA 127
Query: 126 ISFDRYFCVTKPLTYPARRTTK-MAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQ 184
IS DRY V P+ Y R ++K +MI+ WVLSF + P + G N+
Sbjct: 128 ISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLF------GLNNADQNE 181
Query: 185 CFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAF 244
C I +NPA ++I +FY+P ++ ++YI I + R R + K A
Sbjct: 182 CII---ANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRR---RKRVNTKRSSRAFRAH 235
Query: 245 LKSPLMKQSVKKPPPGEAAR--EELRNGKLEEAPPP------ALPPPPRPVADKDTSNES 296
L++PL EAAR +EL L PP +PP + D S+
Sbjct: 236 LRAPLK----------EAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHG 285
Query: 297 SSGSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTA 356
+TP PA P + + +KI + + T+
Sbjct: 286 LH--------------------STPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTS 325
Query: 357 IEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPY 416
++ + +++ +E+K T+ + +L FI+ W P+
Sbjct: 326 LK-------------------------TMSRRKLSQQKEKKATQMLAIVLGVFIICWLPF 360
Query: 417 NVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLC 470
+ ++N C IP ++S WL YVNS +NP Y N F+K F +L C
Sbjct: 361 FITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 414
>gi|4503385 dopamine receptor D2 isoform long [Homo sapiens]
Length = 443
Score = 159 bits (403), Expect = 4e-39
Identities = 126/482 (26%), Positives = 200/482 (41%), Gaps = 76/482 (15%)
Query: 6 PVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQT 65
P NGS G +N Y T+ + IA + V GN+LV +++ + LQT
Sbjct: 21 PFNGSDGKAD-----RPHYNYYATLLTLLIAVI--------VFGNVLVCMAVSREKALQT 67
Query: 66 VNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLI 125
NY + SLA ADL++ M + G W + CD+++ LD ++ AS++NL
Sbjct: 68 TTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCA 127
Query: 126 ISFDRYFCVTKPLTYPARRTTK-MAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQ 184
IS DRY V P+ Y R ++K +MI+ WVLSF + P + G N+
Sbjct: 128 ISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLF------GLNNADQNE 181
Query: 185 CFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAF 244
C I +NPA ++I +FY+P ++ ++YI I + R R + K A
Sbjct: 182 CII---ANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRR---RKRVNTKRSSRAFRAH 235
Query: 245 LKSPL----------------MKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVA 288
L++PL MK + P R +LE + PP R
Sbjct: 236 LRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPER--- 292
Query: 289 DKDTSNESSSGSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQ 348
T S Q T P+ +TP PA P + + +KI +
Sbjct: 293 ---TRYSPIPPSHHQLTLPDPSHH---GLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTM 346
Query: 349 TGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLA 408
+ T+++ + +++ +E+K T+ + +L
Sbjct: 347 PNGKTRTSLK-------------------------TMSRRKLSQQKEKKATQMLAIVLGV 381
Query: 409 FILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLL 468
FI+ W P+ + ++N C IP ++S WL YVNS +NP Y N F+K F +L
Sbjct: 382 FIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKIL 441
Query: 469 LC 470
C
Sbjct: 442 HC 443
>gi|71773208 alpha-2C-adrenergic receptor [Homo sapiens]
Length = 462
Score = 149 bits (375), Expect = 7e-36
Identities = 126/480 (26%), Positives = 207/480 (43%), Gaps = 61/480 (12%)
Query: 9 GSSGNQSVRLVTSSS----HNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQ 64
G G+ V + +S +Y + +A V G L + TVVGN+LV++++ +R L+
Sbjct: 24 GERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALR 83
Query: 65 TVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLL 124
N FL SLA AD+++ M + YW G V C ++LALD + +S+++L
Sbjct: 84 APQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLC 143
Query: 125 IISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQ 184
IS DRY+ VT+ + Y +RT + I A W++S V+ P + V PD
Sbjct: 144 AISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPL------VSLYRQPDGA 197
Query: 185 CFIQFLSNPAVTF--GTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTL 242
+ Q N + + I +F+ P +IM ++Y I RV K R EK+A
Sbjct: 198 AYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARI-----YRVAKLRTRTLSEKRAPVG 252
Query: 243 AFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSAT 302
SP + + AA NG APPPA P S +A
Sbjct: 253 PDGASPTTENGL------GAAAGAGENGHC--APPPADVEP------------DESSAAA 292
Query: 303 QNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPA 362
+ + R A A + P + S ++ G
Sbjct: 293 ERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPG------------ 340
Query: 363 TPAG--MRPAANVARKFAS---IARNQVRKKRQMAARERKVTRTIFAILLAFILTWTP-- 415
P G R ++ F S AR+ V +++ ARE++ T + ++ F+L W P
Sbjct: 341 -PGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFF 399
Query: 416 --YNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYR 473
Y++ + CQ +P ++ +W+ Y NS++NP Y + N F+++F+H+L + R
Sbjct: 400 FSYSLYGICREACQ--VPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRR 457
>gi|32483397 dopamine receptor D4 [Homo sapiens]
Length = 419
Score = 144 bits (363), Expect = 2e-34
Identities = 115/444 (25%), Positives = 181/444 (40%), Gaps = 75/444 (16%)
Query: 36 ATVTGSLSLVTVV--GNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYI 93
A + G + L+ V GN LV +S+ R LQT N F+ SLA ADL++ + L+
Sbjct: 36 AALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSE 95
Query: 94 IKG-YWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLM 152
++G W L +CD +A+D ++ AS+ NL IS DR+ V PL Y + ++ L+
Sbjct: 96 VQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLL 155
Query: 153 IAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMT 212
I A W+LS + AP + G V + L + +++ +F+LP +M
Sbjct: 156 IGATWLLSAAVAAPVL------CGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLML 209
Query: 213 VLY-------IHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAARE 265
+LY +A R+++H P P
Sbjct: 210 LLYWATFRGLQRWEVARRAKLHGRAPRRP------------------------------- 238
Query: 266 ELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELSTTEATTPAMPA 325
P P P PP P +D + A + + + P++P
Sbjct: 239 --------SGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCA---PAAPSLPQ 287
Query: 326 PPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQV 385
P P PA + + V A + P TP R
Sbjct: 288 DPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRR---------------- 331
Query: 386 RKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSC-IPDTVWSIGYWLCYV 444
R++ ++ RERK R + ++ AF+L WTP+ V+ + C +C +P + S WL YV
Sbjct: 332 RRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYV 391
Query: 445 NSTINPACYALCNATFKKTFRHLL 468
NS +NP Y + NA F+ FR L
Sbjct: 392 NSALNPVIYTVFNAEFRNVFRKAL 415
>gi|194353970 alpha-2A-adrenergic receptor [Homo sapiens]
Length = 465
Score = 141 bits (356), Expect = 1e-33
Identities = 116/440 (26%), Positives = 191/440 (43%), Gaps = 40/440 (9%)
Query: 35 IATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYII 94
+ + G L L+TV GN+LV++++ +R L+ N FL SLA AD+++ + +
Sbjct: 51 LVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEV 110
Query: 95 KGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIA 154
GYW G C+++LALD + +S+++L IS DRY+ +T+ + Y +RT + +I
Sbjct: 111 MGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIII 170
Query: 155 AAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVL 214
WV+S V+ P ++ + G + + + I +F+ P +IM ++
Sbjct: 171 TVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILV 230
Query: 215 YIHISLAS--RSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKL 272
Y+ I + R+RV R GP A + P + PG A E L +L
Sbjct: 231 YVRIYQIAKRRTRVPPSR-RGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPT-QL 288
Query: 273 EEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELSTTEATTPAMPAPPLQPRA 332
AP P PR D SSS A ERP P P PR
Sbjct: 289 NGAPGEPAPAGPRDTDALDLEESSSSDHA-----ERP-----------PGPRRPERGPRG 332
Query: 333 LNPASRWSKIQ----IVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKK 388
A R S+++ + + G T I A P R A A ++
Sbjct: 333 KGKA-RASQVKPGDSLPRRGPG---ATGIGTPAAGPGEERVGAAKASRW----------- 377
Query: 389 RQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTI 448
R RE++ T + ++ F++ W P+ T +P T++ +W Y NS++
Sbjct: 378 RGRQNREKRFTFVLAVVIGVFVVCWFPF-FFTYTLTAVGCSVPRTLFKFFFWFGYCNSSL 436
Query: 449 NPACYALCNATFKKTFRHLL 468
NP Y + N F++ F+ +L
Sbjct: 437 NPVIYTIFNHDFRRAFKKIL 456
>gi|33598960 alpha-2B-adrenergic receptor [Homo sapiens]
Length = 450
Score = 139 bits (350), Expect = 6e-33
Identities = 116/466 (24%), Positives = 203/466 (43%), Gaps = 55/466 (11%)
Query: 27 YETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSM 86
Y IA L L T+ GN LV+L++ +R L+ N FL SLA AD+++ +
Sbjct: 7 YSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLII 66
Query: 87 NLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTT 146
+ GYW C+++LALD + +S+++L IS DRY+ V++ L Y ++RT
Sbjct: 67 PFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTP 126
Query: 147 KMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYL 206
+ +I W+++ V+ P +++ + G + QC + ++I +F+
Sbjct: 127 RRIKCIILTVWLIAAVISLPPLIY-KGDQGPQPRGRPQCKLN--QEAWYILASSIGSFFA 183
Query: 207 PVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREE 266
P +IM ++Y+ I L ++ + GP+ K K P +P G
Sbjct: 184 PCLIMILVYLRIYLIAK----RSNRRGPRAKGGPGQGESKQP-------RPDHG------ 226
Query: 267 LRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELST-TEATTPAMPA 325
G L A PAL A ++ E + S + KE T T T A P+ A
Sbjct: 227 ---GALASAKLPAL-------ASVASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAA 276
Query: 326 PPL----QPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATPAG--------------- 366
P Q + AS + + ++ E + VP +PA
Sbjct: 277 LPNSGQGQKEGVCGASPEDEAEEEEEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVL 336
Query: 367 --MRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNT 424
+R + R +I R++ Q+ RE++ T + ++ F+L W P+ +
Sbjct: 337 ATLRGQVLLGRGVGAIGGQWWRRRAQL-TREKRFTFVLAVVIGVFVLCWFPFFFSYSLGA 395
Query: 425 FC-QSC-IPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLL 468
C + C +P ++ +W+ Y NS++NP Y + N F++ FR +L
Sbjct: 396 ICPKHCKVPHGLFQFFFWIGYCNSSLNPVIYTIFNQDFRRAFRRIL 441
>gi|89191861 dopamine receptor D3 isoform a [Homo sapiens]
Length = 400
Score = 137 bits (344), Expect = 3e-32
Identities = 120/437 (27%), Positives = 188/437 (43%), Gaps = 81/437 (18%)
Query: 41 SLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVY--IIKGYW 98
+L L V GN LV +++ R LQT NY + SLA ADL++ M + VY + G W
Sbjct: 38 ALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMP-WVVYLEVTGGVW 96
Query: 99 PLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTY---PARRTTKMAGLMIAA 155
+ CD+++ LD ++ AS++NL IS DRY V P+ Y + + + LMI A
Sbjct: 97 NFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITA 156
Query: 156 AWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLY 215
WVL+F + P +LF G TV C I SNP +++ +FYLP + ++Y
Sbjct: 157 VWVLAFAVSCP-LLFGFNTTGDPTV----CSI---SNPDFVIYSSVVSFYLPFGVTVLVY 208
Query: 216 IHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEA 275
I + + R K + SV+ PG
Sbjct: 209 ARIYVVLKQRRRKR-------------ILTRQNSQCNSVR---PG--------------F 238
Query: 276 PPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELSTTEATTPAMPAPPLQPRALNP 335
P L P P + K + + + EL E T ++ +P + P
Sbjct: 239 PQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSL-SPTIAP----- 292
Query: 336 ASRWSKIQI-VTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAAR 394
K+ + V K + T++++ P P G+ +R+K
Sbjct: 293 -----KLSLEVRKLSNGRLSTSLKLGPLQPRGV----------------PLREK------ 325
Query: 395 ERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSC-IPDTVWSIGYWLCYVNSTINPACY 453
K T+ + +L AFI+ W P+ + ++NT CQ+C + ++S WL YVNS +NP Y
Sbjct: 326 --KATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIY 383
Query: 454 ALCNATFKKTFRHLLLC 470
N F+K F +L C
Sbjct: 384 TTFNIEFRKAFLKILSC 400
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 130 bits (327), Expect = 3e-30
Identities = 71/222 (31%), Positives = 115/222 (51%), Gaps = 4/222 (1%)
Query: 33 VFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVY 92
V + + ++L T + N V+ ++ R+L T NY + SLA DL++ M + T+Y
Sbjct: 50 VLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMY 109
Query: 93 IIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLM 152
+ G W LG VVCD WL+ D AS+++L +I+ DRY+ +T + Y A+RT K A +M
Sbjct: 110 TVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVM 169
Query: 153 IAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMT 212
IA WV S + P FW+ + V ++C + + T + + AFY P +++
Sbjct: 170 IALVWVFSISISLPP-FFWRQAKAEEEV--SECVVN-TDHILYTVYSTVGAFYFPTLLLI 225
Query: 213 VLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSV 254
LY I + +RSR+ K P ++ + SP SV
Sbjct: 226 ALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSV 267
Score = 73.9 bits (180), Expect = 3e-13
Identities = 46/135 (34%), Positives = 71/135 (52%), Gaps = 4/135 (2%)
Query: 338 RWSKIQIVTKQTGN-ECVTAIEI-VPATPAGMRPAANVARKFASIARNQVRKKRQMAARE 395
R ++ Q++T G+ VT+I VP P+ V + ++ + KK+ MAARE
Sbjct: 250 RLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARE 309
Query: 396 RKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSC--IPDTVWSIGYWLCYVNSTINPACY 453
RK T+T+ IL AFI+ W P+ ++ LV C+ ++ WL Y+NS INP Y
Sbjct: 310 RKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIY 369
Query: 454 ALCNATFKKTFRHLL 468
+ N FK+ F L+
Sbjct: 370 TMSNEDFKQAFHKLI 384
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 128 bits (322), Expect = 1e-29
Identities = 70/222 (31%), Positives = 115/222 (51%), Gaps = 13/222 (5%)
Query: 2 ANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNR 61
ANFT N +S N ++ + + + + V G+ L +VGNILV+LS+ NR
Sbjct: 23 ANFTGPNQTSSNSTLP--------QLDITRAISVGLVLGAFILFAIVGNILVILSVACNR 74
Query: 62 QLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVM 121
L+T NYF+ +LA ADL++ + + GYW LG + CD+W A+D + AS++
Sbjct: 75 HLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASIL 134
Query: 122 NLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVP 181
+L IS DRY V L YP T + A L + + WVLS V+ +L W K P
Sbjct: 135 SLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGW-----KEPAP 189
Query: 182 DNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASR 223
++ P +++ +FY+P+ ++ V+Y + + ++
Sbjct: 190 NDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAK 231
Score = 61.6 bits (148), Expect = 2e-09
Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 1/99 (1%)
Query: 382 RNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV-LVNTFCQSCIPDTVWSIGYW 440
R+ + K +RE+K +T+ ++ FIL W P+ + + L + F PD V+ + +W
Sbjct: 276 RSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFW 335
Query: 441 LCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR 479
L Y NS +NP Y + FK+ F +L CQ R G R
Sbjct: 336 LGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRR 374
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 128 bits (322), Expect = 1e-29
Identities = 68/208 (32%), Positives = 110/208 (52%), Gaps = 6/208 (2%)
Query: 33 VFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVY 92
V + + L+ V GN+LV+LS+ NR LQTV NYF+ +LA ADL++ A +
Sbjct: 97 VGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATM 156
Query: 93 IIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLM 152
+ G+W G CD+W A+D + AS+++L IS DRY V L YPA T + A +
Sbjct: 157 EVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAI 216
Query: 153 IAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMT 212
+A WV++ V+ +L W K VP ++ F +++ +FYLP+ ++
Sbjct: 217 LALLWVVALVVSVGPLLGW-----KEPVPPDERFCGITEEAGYAVFSSVCSFYLPMAVIV 271
Query: 213 VLYIHISLASRSRVHKHRPEGPKEKKAK 240
V+Y + + +RS + G K ++ K
Sbjct: 272 VMYCRVYVVARSTT-RSLEAGVKRERGK 298
Score = 56.6 bits (135), Expect = 5e-08
Identities = 29/82 (35%), Positives = 46/82 (56%), Gaps = 1/82 (1%)
Query: 393 ARERKVTRTIFAILLAFILTWTPYN-VMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPA 451
+RE+K +T+ ++ F+L W P+ V+ L + F Q + V+ + +WL Y NS +NP
Sbjct: 341 SREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPL 400
Query: 452 CYALCNATFKKTFRHLLLCQYR 473
Y + FK+ F LL CQ R
Sbjct: 401 IYPCSSREFKRAFLRLLRCQCR 422
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 127 bits (320), Expect = 2e-29
Identities = 61/191 (31%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Query: 33 VFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVY 92
+ + + G L L V+GNILV+LS+ +R L +V +Y++ +LA ADL++ + + ++
Sbjct: 27 ILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIF 86
Query: 93 IIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLM 152
+ GYW G V C++W A+D + AS+M L IIS DRY V+ PL YP T + +
Sbjct: 87 EVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMA 146
Query: 153 IAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMT 212
+ W LS V+ + W ++ P+++ Q P +A+ +FYLP+ I+
Sbjct: 147 LLCVWALSLVISIGPLFGW-----RQPAPEDETICQINEEPGYVLFSALGSFYLPLAIIL 201
Query: 213 VLYIHISLASR 223
V+Y + + ++
Sbjct: 202 VMYCRVYVVAK 212
Score = 59.7 bits (143), Expect = 6e-09
Identities = 28/80 (35%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Query: 393 ARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIP-DTVWSIGYWLCYVNSTINPA 451
+RE+K +T+ ++ F+L W P+ +++ + +F P +TV+ I +WL Y+NS INP
Sbjct: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPI 324
Query: 452 CYALCNATFKKTFRHLLLCQ 471
Y + FKK F+++L Q
Sbjct: 325 IYPCSSQEFKKAFQNVLRIQ 344
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 127 bits (320), Expect = 2e-29
Identities = 61/191 (31%), Positives = 106/191 (55%), Gaps = 5/191 (2%)
Query: 33 VFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVY 92
+ + + G L L V+GNILV+LS+ +R L +V +Y++ +LA ADL++ + + ++
Sbjct: 27 ILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIF 86
Query: 93 IIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLM 152
+ GYW G V C++W A+D + AS+M L IIS DRY V+ PL YP T + +
Sbjct: 87 EVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMA 146
Query: 153 IAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMT 212
+ W LS V+ + W ++ P+++ Q P +A+ +FYLP+ I+
Sbjct: 147 LLCVWALSLVISIGPLFGW-----RQPAPEDETICQINEEPGYVLFSALGSFYLPLAIIL 201
Query: 213 VLYIHISLASR 223
V+Y + + ++
Sbjct: 202 VMYCRVYVVAK 212
Score = 59.7 bits (143), Expect = 6e-09
Identities = 28/80 (35%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Query: 393 ARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIP-DTVWSIGYWLCYVNSTINPA 451
+RE+K +T+ ++ F+L W P+ +++ + +F P +TV+ I +WL Y+NS INP
Sbjct: 265 SREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPI 324
Query: 452 CYALCNATFKKTFRHLLLCQ 471
Y + FKK F+++L Q
Sbjct: 325 IYPCSSQEFKKAFQNVLRIQ 344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.133 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,822,643
Number of Sequences: 37866
Number of extensions: 932541
Number of successful extensions: 13473
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 674
Number of HSP's successfully gapped in prelim test: 652
Number of HSP's that attempted gapping in prelim test: 9026
Number of HSP's gapped (non-prelim): 3652
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.