BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13377002 crystallin, gamma D [Homo sapiens] (174 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13377002 crystallin, gamma D [Homo sapiens] 375 e-104 gi|148491074 crystallin, gamma B [Homo sapiens] 283 5e-77 gi|148491057 crystallin, gamma A [Homo sapiens] 278 2e-75 gi|10518338 crystallin, gamma C [Homo sapiens] 273 5e-74 gi|8922120 crystallin, gamma S [Homo sapiens] 199 1e-51 gi|89886227 absent in melanoma 1-like [Homo sapiens] 110 5e-25 gi|4758074 crystallin, beta B3 [Homo sapiens] 106 1e-23 gi|12056461 crystallin, beta A3 [Homo sapiens] 104 3e-23 gi|4503061 crystallin, beta B1 [Homo sapiens] 103 8e-23 gi|4503063 crystallin, beta B2 [Homo sapiens] 103 1e-22 gi|4503059 crystallin, beta A4 [Homo sapiens] 95 3e-20 gi|21389517 gammaN-crystallin [Homo sapiens] 92 2e-19 gi|16936542 crystallin, beta A2 [Homo sapiens] 89 2e-18 gi|16936540 crystallin, beta A2 [Homo sapiens] 89 2e-18 gi|7019357 crystallin, beta A2 [Homo sapiens] 89 2e-18 gi|62988361 absent in melanoma 1 [Homo sapiens] 89 2e-18 gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi... 82 2e-16 gi|164420681 methionyl aminopeptidase 1 [Homo sapiens] 29 2.3 gi|42734438 hypothetical protein LOC51571 [Homo sapiens] 28 5.2 >gi|13377002 crystallin, gamma D [Homo sapiens] Length = 174 Score = 375 bits (963), Expect = e-104 Identities = 174/174 (100%), Positives = 174/174 (100%) Query: 1 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR Sbjct: 1 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 Query: 61 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE Sbjct: 61 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120 Query: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS 174 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS Sbjct: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS 174 >gi|148491074 crystallin, gamma B [Homo sapiens] Length = 175 Score = 283 bits (724), Expect = 5e-77 Identities = 126/173 (72%), Positives = 150/173 (86%), Gaps = 1/173 (0%) Query: 1 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 MGKIT YEDR FQGR YEC++D PNLQPY SRCNS RV+SGCWM+YE+PNY G QYFLRR Sbjct: 1 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR 60 Query: 61 GDYADHQQWMGLSDSVRSCRLI-PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFN 119 G+Y D+QQWMGLSDS+RSC LI PHSG++R+++Y+R++ RGQM E T+DC +QDRF Sbjct: 61 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLT 120 Query: 120 EIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172 EIHSLNVLEGSW+LYE+ NYRGRQYLL PG+YRR+ DWGA NA+VGSLRRV+D Sbjct: 121 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMD 173 >gi|148491057 crystallin, gamma A [Homo sapiens] Length = 174 Score = 278 bits (711), Expect = 2e-75 Identities = 125/172 (72%), Positives = 143/172 (83%) Query: 1 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 MGKIT YEDR FQGR Y C SD PNL+ Y SRCNS RVDSGCWMLYE+PNY G QYFLRR Sbjct: 1 MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR 60 Query: 61 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120 G Y D+Q WMGLSDSV+SCR+IPH+ SH++RLYER+DYRG M E T+DC+C+ + FR E Sbjct: 61 GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120 Query: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172 I+SL+VLEG WVLYE+ NYRGRQYLL PGDYRRY DWG +A+VGSLRRV D Sbjct: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTD 172 >gi|10518338 crystallin, gamma C [Homo sapiens] Length = 174 Score = 273 bits (698), Expect = 5e-74 Identities = 124/172 (72%), Positives = 144/172 (83%) Query: 1 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 MGKIT YEDR FQGR YE ++D PNLQPY SRCNS RV+SGCWMLYE+PNY G QY LRR Sbjct: 1 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR 60 Query: 61 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120 G+Y D+QQWMGLSDS+RSC LIP + SHR+RLYERED++G M+E +EDC +QDRF +E Sbjct: 61 GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120 Query: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172 I SL+VLEG WVLYEL NYRGRQYLL P +YRR QDWGA +A+ GSLRRV+D Sbjct: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVD 172 >gi|8922120 crystallin, gamma S [Homo sapiens] Length = 178 Score = 199 bits (505), Expect = 1e-51 Identities = 86/172 (50%), Positives = 120/172 (69%), Gaps = 2/172 (1%) Query: 3 KITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRGD 62 KIT YED+ FQGR Y+C D + YLSRCNS +V+ G W +YE+PN++G Y L +G+ Sbjct: 7 KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66 Query: 63 YADHQQWMGLSDSVRSCRLI--PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120 Y ++Q+WMGL+D + SCR + P G ++I+++E+ D+ GQM E TEDC + ++F E Sbjct: 67 YPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126 Query: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172 IHS VLEG W+ YEL NYRGRQYLL +YR+ DWGA + V S RR+++ Sbjct: 127 IHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178 >gi|89886227 absent in melanoma 1-like [Homo sapiens] Length = 616 Score = 110 bits (276), Expect = 5e-25 Identities = 62/177 (35%), Positives = 93/177 (52%), Gaps = 8/177 (4%) Query: 3 KITLYEDRGFQGRHYECSSDHPNLQ-------PYLSRCNSARVDSGCWMLYEQPNYSGLQ 55 + +YE GFQGR +E S D NLQ P+L+ S RV GCW+ YE+ + G Q Sbjct: 124 RAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQ 183 Query: 56 YFLRRGDYADHQQWMGLSDSVRSCRLI-PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114 Y L G+Y D W G + + S R+I G + L+E D+ G +E ++ ++ Sbjct: 184 YLLEEGEYPDWSHWGGYDELLTSLRVIRTDFGDPAVVLFEAMDFEGHGVEVSKALPDVEL 243 Query: 115 RFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVI 171 +++VL G WV Y+ + G QY+L G YR +DWGA N+ + SL+ V+ Sbjct: 244 VQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPVL 300 Score = 82.0 bits (201), Expect = 2e-16 Identities = 55/180 (30%), Positives = 80/180 (44%), Gaps = 14/180 (7%) Query: 3 KITLYEDRGFQGRHYECSSDHPNLQPYLS--RCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 +I+L+ + G +G + + N Q + SA V +G W+LY +P + Y L Sbjct: 29 EISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEP 88 Query: 61 GDYADHQQWMGLSDSVRS-------CRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQ 113 G+Y + W SV S C + G R +YE ++G+ E + D LQ Sbjct: 89 GEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNLQ 148 Query: 114 DRFRFNEIH-----SLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLR 168 H SL VL G WV YE +RG QYLL G+Y + WG + + SLR Sbjct: 149 QPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDELLTSLR 208 Score = 79.3 bits (194), Expect = 2e-15 Identities = 50/176 (28%), Positives = 88/176 (50%), Gaps = 12/176 (6%) Query: 4 ITLYEDRGFQGRHYECSSDHPNLQ--PYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 + L+E F+G E S P+++ + + V SG W+ Y++ +SG QY L +G Sbjct: 219 VVLFEAMDFEGHGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKG 278 Query: 62 DYADHQQWMGLSDSVRSCRLIPHSGSH------RIRLYEREDYRGQMIEFTEDCSCLQDR 115 Y + + W + ++ S + + G H +I+L+ R D+ G F +D + L Sbjct: 279 VYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAALPAS 338 Query: 116 FRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARV-GSLRRV 170 FR S V GSW+L++ +N+ G Q++L G++ G + V GSL++V Sbjct: 339 FR---PQSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLASTVLGSLQKV 391 Score = 74.7 bits (182), Expect = 4e-14 Identities = 52/169 (30%), Positives = 81/169 (47%), Gaps = 4/169 (2%) Query: 1 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 + KI L+ F G H+ D L P R S RV G W+L+++ N+ G Q+ L Sbjct: 310 VSKIQLFSRPDFLGDHFSFEDDQAAL-PASFRPQSCRVHGGSWILFDETNFEGDQHILSE 368 Query: 61 GDYADHQQWMGLSDSVRSC--RLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRF 118 G++ L+ +V ++ H I LY E + G+ IE + + LQ Sbjct: 369 GEFPTLTAMGCLASTVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVRSLQAEGFN 428 Query: 119 NEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSL 167 N + S+ + G WVL E S++RGRQ+L+ + + + T RVGSL Sbjct: 429 NHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCEITNWLTYSGTQ-RVGSL 476 Score = 49.3 bits (116), Expect = 2e-06 Identities = 25/89 (28%), Positives = 44/89 (49%) Query: 80 RLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNY 139 R++ + I L+ E +G+ ++ TE Q + ++ S V G W+LY + Sbjct: 20 RVVWDYSTPEISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLF 79 Query: 140 RGRQYLLMPGDYRRYQDWGATNARVGSLR 168 Y+L PG+Y + WG ++ VGSL+ Sbjct: 80 EDTPYILEPGEYPTSEAWGTSDPSVGSLK 108 >gi|4758074 crystallin, beta B3 [Homo sapiens] Length = 211 Score = 106 bits (264), Expect = 1e-23 Identities = 60/180 (33%), Positives = 93/180 (51%), Gaps = 15/180 (8%) Query: 3 KITLYEDRGFQGRHYECSSDHPNL-QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 K+ LYE FQG+ E S++ P+L L + S +V+SG W+ +E + G Q+ L +G Sbjct: 25 KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84 Query: 62 DYADHQQWMGLSDSVRSCRLIP---HSGSHRIRLYEREDYRGQMIEFTED------CSCL 112 DY W DS L P S H++ L+E + G+ +E +D Sbjct: 85 DYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGF 144 Query: 113 QDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172 QDR + S+ + G+WV YE YRGRQY+ G+YR + +W A+ ++ S+RR+ D Sbjct: 145 QDR-----VASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRD 199 Score = 57.8 bits (138), Expect = 5e-09 Identities = 25/72 (34%), Positives = 43/72 (59%), Gaps = 1/72 (1%) Query: 86 GSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYL 145 GS+++ LYE E+++G+ E + +C L D ++ S+ V G W+ +E +RG Q++ Sbjct: 22 GSYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFRGEQFV 80 Query: 146 LMPGDYRRYQDW 157 L GDY R+ W Sbjct: 81 LEKGDYPRWDAW 92 Score = 50.8 bits (120), Expect = 6e-07 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 3/90 (3%) Query: 3 KITLYEDRGFQGRHYECSSDH-PNL--QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLR 59 K+ L+E+ F GR E D P+L + R S R +G W+ YE P Y G QY Sbjct: 115 KLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFE 174 Query: 60 RGDYADHQQWMGLSDSVRSCRLIPHSGSHR 89 RG+Y +W ++S R I H+ Sbjct: 175 RGEYRHWNEWDASQPQLQSVRRIRDQKWHK 204 >gi|12056461 crystallin, beta A3 [Homo sapiens] Length = 215 Score = 104 bits (260), Expect = 3e-23 Identities = 61/183 (33%), Positives = 103/183 (56%), Gaps = 16/183 (8%) Query: 3 KITLYEDRGFQGRHYECSSDHPNL-QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 KIT+Y+ FQG+ E +S PN+ + S +V+SG W+ YE ++ G Q+ L RG Sbjct: 32 KITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERG 91 Query: 62 DYADHQQWMGLSDSVRSCRLIPH----SGSH---RIRLYEREDYRGQMIEFTEDCSCLQD 114 +Y W G S++ RL+ S +H ++ ++E+E++ G+ E ++D LQ Sbjct: 92 EYPRWDAWSG-SNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYPSLQA 150 Query: 115 RFRF-NEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWG--ATNARVGSL 167 F NE+ S+ + G+WV Y+ YRG QY+L GDY+ +++WG A +++ S+ Sbjct: 151 MGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSI 210 Query: 168 RRV 170 RR+ Sbjct: 211 RRI 213 Score = 65.1 bits (157), Expect = 3e-11 Identities = 27/77 (35%), Positives = 51/77 (66%), Gaps = 1/77 (1%) Query: 86 GSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYL 145 G +I +Y++E+++G+ +EFT C + +R F+ + SL V G+W+ YE +++ G+Q++ Sbjct: 29 GPWKITIYDQENFQGKRMEFTSSCPNVSER-SFDNVRSLKVESGAWIGYEHTSFCGQQFI 87 Query: 146 LMPGDYRRYQDWGATNA 162 L G+Y R+ W +NA Sbjct: 88 LERGEYPRWDAWSGSNA 104 >gi|4503061 crystallin, beta B1 [Homo sapiens] Length = 252 Score = 103 bits (257), Expect = 8e-23 Identities = 62/178 (34%), Positives = 95/178 (53%), Gaps = 11/178 (6%) Query: 3 KITLYEDRGFQGRHYECSSDHPNLQPY-LSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 ++ ++E FQGR E S + NL R S V +G W+ +EQ N+ G + L +G Sbjct: 60 RLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKG 119 Query: 62 DYADHQQWMGLSDSVRSCRLIPH------SGSHRIRLYEREDYRGQMIEFTEDCSCLQDR 115 +Y W S S RS RL+ + H+I L+E +++G IE D + Sbjct: 120 EYPRWNTW---SSSYRSDRLMSFRPIKMDAQEHKISLFEGANFKGNTIEIQGDDAPSLWV 176 Query: 116 FRFNE-IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172 + F++ + S+ V G+WV Y+ YRG QYLL PGD+R + +WGA ++ SLRR+ D Sbjct: 177 YGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRLRD 234 Score = 66.2 bits (160), Expect = 1e-11 Identities = 31/86 (36%), Positives = 55/86 (63%), Gaps = 3/86 (3%) Query: 75 SVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLY 134 S ++ L P G++R+ ++E E+++G+ EF+ +CS L DR F+ + S+ V G WV + Sbjct: 48 SAKAAELPP--GNYRLVVFELENFQGRRAEFSGECSNLADR-GFDRVRSIIVSAGPWVAF 104 Query: 135 ELSNYRGRQYLLMPGDYRRYQDWGAT 160 E SN+RG ++L G+Y R+ W ++ Sbjct: 105 EQSNFRGEMFILEKGEYPRWNTWSSS 130 >gi|4503063 crystallin, beta B2 [Homo sapiens] Length = 205 Score = 103 bits (256), Expect = 1e-22 Identities = 62/175 (35%), Positives = 93/175 (53%), Gaps = 5/175 (2%) Query: 3 KITLYEDRGFQGRHYECSSDHPNLQPY-LSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 KI ++E FQG +E + PNL+ + + S V +G W+ YEQ N G Q+ +G Sbjct: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77 Query: 62 DYADHQQWMGL--SDSVRSCRLIP-HSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRF 118 +Y W +DS+ S R I S H+I LYE ++ G+ +E +D + Sbjct: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGKKMEIIDDDVPSFHAHGY 137 Query: 119 NE-IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172 E + S+ V G+WV Y+ YRG QYLL GDY+ D+GA + +V S+RR+ D Sbjct: 138 QEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRIRD 192 Score = 46.2 bits (108), Expect = 1e-05 Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 2/85 (2%) Query: 83 PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGR 142 P S + +I ++E+E+++G E C L++ + S+ V G WV YE +N +G Sbjct: 12 PQSLNPKIIIFEQENFQGHSHELNGPCPNLKET-GVEKAGSVLVQAGPWVGYEQANCKGE 70 Query: 143 QYLLMPGDYRRYQDWGATNARVGSL 167 Q++ G+Y R+ W ++ R SL Sbjct: 71 QFVFEKGEYPRWDSW-TSSRRTDSL 94 >gi|4503059 crystallin, beta A4 [Homo sapiens] Length = 196 Score = 95.1 bits (235), Expect = 3e-20 Identities = 59/183 (32%), Positives = 98/183 (53%), Gaps = 16/183 (8%) Query: 3 KITLYEDRGFQGRHYECSSDHPN-LQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 K+ ++++ GFQGR +E +++ P+ L+ S +V SG W+ +E + G QY L RG Sbjct: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72 Query: 62 DYADHQQWMGLS-------DSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114 +Y W G + S R H S R+ ++E+E++ G+ E ++D LQ Sbjct: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDS-RLTIFEQENFLGKKGELSDDYPSLQA 131 Query: 115 R-FRFNEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWG--ATNARVGSL 167 + NE+ S +V G+WV + YRG QY+L GDY+ +++WG A +V S+ Sbjct: 132 MGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSI 191 Query: 168 RRV 170 RR+ Sbjct: 192 RRI 194 Score = 56.2 bits (134), Expect = 1e-08 Identities = 24/78 (30%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Query: 85 SGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQY 144 +G ++ +++ + ++G+ EFT +C + + F + SL VL G+WV +E + ++G+QY Sbjct: 9 AGPWKMVVWDEDGFQGRRHEFTAECPSVLE-LGFETVRSLKVLSGAWVGFEHAGFQGQQY 67 Query: 145 LLMPGDYRRYQDWGATNA 162 +L G+Y + WG A Sbjct: 68 ILERGEYPSWDAWGGNTA 85 >gi|21389517 gammaN-crystallin [Homo sapiens] Length = 182 Score = 92.4 bits (228), Expect = 2e-19 Identities = 47/117 (40%), Positives = 67/117 (57%), Gaps = 3/117 (2%) Query: 2 GKITLYEDRGFQGRHYECSSDHPNLQP--YLSRCNSARVDSGCWMLYEQPNYSGLQYFLR 59 GKITLYE + F G+ E D N Q +++R NS V+SG W+ + P++ G Q+ L Sbjct: 6 GKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILE 65 Query: 60 RGDYADHQQWMGLSDSVRSCRLIPHSGSH-RIRLYEREDYRGQMIEFTEDCSCLQDR 115 GDY D +W SD + SCR + G H R+ ++E ++ GQ +EF ED LQ R Sbjct: 66 HGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQSR 122 Score = 66.2 bits (160), Expect = 1e-11 Identities = 31/84 (36%), Positives = 50/84 (59%) Query: 87 SHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLL 146 S +I LYE + + GQ +E DC QDR N ++S++V G+WV + ++RG+Q++L Sbjct: 5 SGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFIL 64 Query: 147 MPGDYRRYQDWGATNARVGSLRRV 170 GDY + W + + +GS R V Sbjct: 65 EHGDYPDFFRWNSHSDHMGSCRPV 88 >gi|16936542 crystallin, beta A2 [Homo sapiens] Length = 197 Score = 88.6 bits (218), Expect = 2e-18 Identities = 56/181 (30%), Positives = 91/181 (50%), Gaps = 16/181 (8%) Query: 4 ITLYEDRGFQGRHYECSSDHPNL--QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 +TL+++ FQGR SD N+ + L R S +V++G W+ +E P++ G Q+ L +G Sbjct: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73 Query: 62 DYADHQQWMGLSD-------SVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114 DY W G S S R H+ S R+ L+E ++++G + +D L Sbjct: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132 Query: 115 R-FRFNEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWGATNARVGSLRR 169 + ++ SL V G+WV Y+ YRG QY+L G++ Y + G T A G L+ Sbjct: 133 MGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELG-TQAHTGQLQS 191 Query: 170 V 170 + Sbjct: 192 I 192 Score = 46.6 bits (109), Expect = 1e-05 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 3/61 (4%) Query: 3 KITLYEDRGFQGRHYECSSDHPNL--QPYLSR-CNSARVDSGCWMLYEQPNYSGLQYFLR 59 ++TL+E FQG ++ D+P+L + S+ S +V SG W+ Y+ P Y G QY L Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166 Query: 60 R 60 R Sbjct: 167 R 167 >gi|16936540 crystallin, beta A2 [Homo sapiens] Length = 197 Score = 88.6 bits (218), Expect = 2e-18 Identities = 56/181 (30%), Positives = 91/181 (50%), Gaps = 16/181 (8%) Query: 4 ITLYEDRGFQGRHYECSSDHPNL--QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 +TL+++ FQGR SD N+ + L R S +V++G W+ +E P++ G Q+ L +G Sbjct: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73 Query: 62 DYADHQQWMGLSD-------SVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114 DY W G S S R H+ S R+ L+E ++++G + +D L Sbjct: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132 Query: 115 R-FRFNEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWGATNARVGSLRR 169 + ++ SL V G+WV Y+ YRG QY+L G++ Y + G T A G L+ Sbjct: 133 MGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELG-TQAHTGQLQS 191 Query: 170 V 170 + Sbjct: 192 I 192 Score = 46.6 bits (109), Expect = 1e-05 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 3/61 (4%) Query: 3 KITLYEDRGFQGRHYECSSDHPNL--QPYLSR-CNSARVDSGCWMLYEQPNYSGLQYFLR 59 ++TL+E FQG ++ D+P+L + S+ S +V SG W+ Y+ P Y G QY L Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166 Query: 60 R 60 R Sbjct: 167 R 167 >gi|7019357 crystallin, beta A2 [Homo sapiens] Length = 197 Score = 88.6 bits (218), Expect = 2e-18 Identities = 56/181 (30%), Positives = 91/181 (50%), Gaps = 16/181 (8%) Query: 4 ITLYEDRGFQGRHYECSSDHPNL--QPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRG 61 +TL+++ FQGR SD N+ + L R S +V++G W+ +E P++ G Q+ L +G Sbjct: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73 Query: 62 DYADHQQWMGLSD-------SVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD 114 DY W G S S R H+ S R+ L+E ++++G + +D L Sbjct: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDS-RVTLFEGDNFQGCKFDLVDDYPSLPS 132 Query: 115 R-FRFNEIHSLNVLEGSWVLYELSNYRGRQYLL----MPGDYRRYQDWGATNARVGSLRR 169 + ++ SL V G+WV Y+ YRG QY+L G++ Y + G T A G L+ Sbjct: 133 MGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRHSGEFCTYGELG-TQAHTGQLQS 191 Query: 170 V 170 + Sbjct: 192 I 192 Score = 46.6 bits (109), Expect = 1e-05 Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 3/61 (4%) Query: 3 KITLYEDRGFQGRHYECSSDHPNL--QPYLSR-CNSARVDSGCWMLYEQPNYSGLQYFLR 59 ++TL+E FQG ++ D+P+L + S+ S +V SG W+ Y+ P Y G QY L Sbjct: 107 RVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLE 166 Query: 60 R 60 R Sbjct: 167 R 167 >gi|62988361 absent in melanoma 1 [Homo sapiens] Length = 1723 Score = 88.6 bits (218), Expect = 2e-18 Identities = 58/190 (30%), Positives = 95/190 (50%), Gaps = 27/190 (14%) Query: 3 KITLYEDRGFQGRHYE-----CS-------------SDHPNLQPYLSRCNSARVDSGCWM 44 K+ +YE F+G+ E CS DH P+ S S +V G W+ Sbjct: 1219 KVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDH---LPFTS-VGSMKVLRGIWV 1274 Query: 45 LYEQPNYSGLQYFLRRGDYADHQQWMGLSDSVRSCRLI--PHSGSHRIRLYEREDY--RG 100 YE+P ++G QY L G+Y D + W G + ++S R I S +H I +Y +++ +G Sbjct: 1275 AYEKPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPILGDFSNAHMI-MYSEKNFGSKG 1333 Query: 101 QMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGAT 160 I+ + L++ + S+NVL G WV YE ++ G QY+L G Y ++DWG Sbjct: 1334 SSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGK 1393 Query: 161 NARVGSLRRV 170 N ++ S++ + Sbjct: 1394 NCKISSVQPI 1403 Score = 85.1 bits (209), Expect = 3e-17 Identities = 50/160 (31%), Positives = 78/160 (48%), Gaps = 20/160 (12%) Query: 35 SARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGLSDSVRSCRLIPHSGSH------ 88 S +V G W++YE+P + G+ + L G+Y D W + + S R + G Sbjct: 1158 SMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYIGSMRPLKMGGRKVEFPTD 1217 Query: 89 -RIRLYEREDYRGQMIEF-TEDCSCLQ-----------DRFRFNEIHSLNVLEGSWVLYE 135 ++ +YE+ + G+ +E T CS + D F + S+ VL G WV YE Sbjct: 1218 PKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVAYE 1277 Query: 136 LSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVI-DFS 174 + G QYLL G+YR ++ WG N + SLR ++ DFS Sbjct: 1278 KPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPILGDFS 1317 Score = 80.9 bits (198), Expect = 5e-16 Identities = 55/169 (32%), Positives = 82/169 (48%), Gaps = 6/169 (3%) Query: 3 KITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRGD 62 +I L+ + FQG + S S RV G W++Y+ N++G QY L G Sbjct: 1416 QIHLFSEPQFQGHSQSFEETTSQIDDSFST-KSCRVSGGSWVVYDGENFTGNQYVLEEGH 1474 Query: 63 YADHQQWMGLSDSV--RSCRLIPHSGSH-RIRLYEREDYRGQMIEFTEDCSCLQDRFRFN 119 Y MG +S R I S I L+ERED++G+ IE + L+ Sbjct: 1475 YPCLSA-MGCPPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIELNAETVNLRSLGFNT 1533 Query: 120 EIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLR 168 +I S+ V+ G WV YE +YRGRQ+LL P + + ++ ++GSLR Sbjct: 1534 QIRSVQVIGGIWVTYEYGSYRGRQFLLSPAEVPNWYEFSGCR-QIGSLR 1581 Score = 62.8 bits (151), Expect = 1e-10 Identities = 49/184 (26%), Positives = 81/184 (44%), Gaps = 19/184 (10%) Query: 2 GKITLYEDRGFQGRHYECSSDHPNLQPY-LSRCNSARVDSGCWMLYEQPNYSGLQYFLRR 60 GK+ +Y + + E SD + + LS +V GCW+LYEQPN+ G L Sbjct: 1022 GKVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGCWILYEQPNFEGHSIPLEE 1081 Query: 61 GDYADHQQWMGLSDSVR--------------SCRLI--PHSGSHRIRLYEREDYRGQMIE 104 G+ W G+ D + S R + + SH I L+ + G + Sbjct: 1082 GELELSGLW-GIEDILERHEEAESDKPVVIGSIRHVVQDYRVSH-IDLFTEPEGLGILSS 1139 Query: 105 FTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARV 164 + +D +Q + S+ V G+W++YE ++G ++L PG+Y W A + Sbjct: 1140 YFDDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYI 1199 Query: 165 GSLR 168 GS+R Sbjct: 1200 GSMR 1203 >gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapiens] Length = 1022 Score = 82.4 bits (202), Expect = 2e-16 Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 8/176 (4%) Query: 3 KITLYEDRGFQGRHYECSSDHPNLQPYLS------RCNSARVDSGCWMLYEQPNYSGLQY 56 K+ +YE F G+ E S ++ +L R S RV G W+ YE+ ++ G Q+ Sbjct: 532 KVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQF 591 Query: 57 FLRRGDYADHQQWMGLSDSVRSCRLIPHSG-SHRIRLYEREDYRGQMIEFT-EDCSCLQD 114 L GD+ D LS + S R + + + L+E + G+ I+ T ++ S L++ Sbjct: 592 LLEEGDFEDSNACGALSSPILSFRYLQANFIESSVTLFESDLESGKFIDITNQEISDLEE 651 Query: 115 RFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRV 170 ++ S++V G WV Y+ + G QY+L G Y+ + DWG +N + S+R + Sbjct: 652 IGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPI 707 Score = 62.8 bits (151), Expect = 1e-10 Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 10/146 (6%) Query: 31 SRCNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGLSDSVRSCRLIP------H 84 S+ S V SG W+ Y+Q + G QY L +G Y W G ++ + S R I + Sbjct: 656 SKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPIQLEPLGIN 715 Query: 85 SGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQY 144 H ++ + + ++G+ I+FTE+ S L S VL G W+LY + Sbjct: 716 EPPHLLKAFSKPGFQGECIDFTEETSDLTSLMPC----SFKVLRGCWLLYYQEDMFVNHC 771 Query: 145 LLMPGDYRRYQDWGATNARVGSLRRV 170 +L G Y G ++V SL+ + Sbjct: 772 VLEEGLYADLTSCGCPASKVKSLKPI 797 Score = 53.1 bits (126), Expect = 1e-07 Identities = 48/161 (29%), Positives = 73/161 (45%), Gaps = 8/161 (4%) Query: 11 GFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWM 70 GFQG + + + +L L C S +V GCW+LY Q + L G YAD Sbjct: 728 GFQGECIDFTEETSDLTS-LMPC-SFKVLRGCWLLYYQEDMFVNHCVLEEGLYADLTSCG 785 Query: 71 GLSDSVRSCRLIPHSGSH-RIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEG 129 + V+S + I + I L+ E G+ + E + + ++ S+ V G Sbjct: 786 CPASKVKSLKPIDYVFEEPSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSVWVKSG 845 Query: 130 SWVLYELSNYRGRQYLLMPGDYRRYQDWGATN--ARVGSLR 168 W+ YE SN+ GRQ LL P + +W A + +GSLR Sbjct: 846 LWIAYEGSNFLGRQILLRPNE---IPNWTAFSRWKTIGSLR 883 Score = 38.1 bits (87), Expect = 0.004 Identities = 19/55 (34%), Positives = 32/55 (58%), Gaps = 7/55 (12%) Query: 124 LNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNAR-------VGSLRRVI 171 + V+ G W+LYE ++RG++ +L G+ +DW N R +GSL+RV+ Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRVL 435 Score = 35.4 bits (80), Expect = 0.025 Identities = 26/120 (21%), Positives = 53/120 (44%), Gaps = 13/120 (10%) Query: 37 RVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWM----------GLSDSVRSCRLIPHSG 86 +V GCW+LYE+P++ G + L G+ ++ W+ + S++ R++ Sbjct: 382 KVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLK--RVLKDCS 439 Query: 87 SHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLL 146 I L+ + D + L++ ++ S V G W+ Y N++G+ +L Sbjct: 440 IPEIELFPQSDPACCPVYIQRAVPNLEE-LNISKSVSFTVKSGVWLAYPDINFKGQATVL 498 >gi|164420681 methionyl aminopeptidase 1 [Homo sapiens] Length = 386 Score = 28.9 bits (63), Expect = 2.3 Identities = 15/47 (31%), Positives = 28/47 (59%), Gaps = 7/47 (14%) Query: 57 FLRRGDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMI 103 +++R DYADH +G+S+S ++ + G+ +I+L ED G + Sbjct: 102 YIQRPDYADHP--LGMSESEQALK-----GTSQIKLLSSEDIEGMRL 141 >gi|42734438 hypothetical protein LOC51571 [Homo sapiens] Length = 324 Score = 27.7 bits (60), Expect = 5.2 Identities = 17/63 (26%), Positives = 34/63 (53%), Gaps = 7/63 (11%) Query: 118 FNEIHSLNVLEGSWVLYELSNYRG-----RQYLLMPGDYRRYQD-WGATNARVGSLRRVI 171 +N+++ + + + +L +L +YRG R+ + P D + + WGA VG L++ Sbjct: 36 YNQVNVV-LKDAEGILEDLQSYRGAGHEIREAIQHPADEKLQEKAWGAVVPLVGKLKKFY 94 Query: 172 DFS 174 +FS Sbjct: 95 EFS 97 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.140 0.456 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,058,133 Number of Sequences: 37866 Number of extensions: 297713 Number of successful extensions: 573 Number of sequences better than 10.0: 19 Number of HSP's better than 10.0 without gapping: 17 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 459 Number of HSP's gapped (non-prelim): 44 length of query: 174 length of database: 18,247,518 effective HSP length: 95 effective length of query: 79 effective length of database: 14,650,248 effective search space: 1157369592 effective search space used: 1157369592 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.