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Search of human proteins with 5174593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5174593 melatonin receptor 1A [Homo sapiens]
(350 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5174593 melatonin receptor 1A [Homo sapiens] 703 0.0
gi|5174595 melatonin receptor 1B [Homo sapiens] 421 e-118
gi|150170722 G protein-coupled receptor 50 [Homo sapiens] 347 1e-95
gi|167000885 galanin receptor 1 [Homo sapiens] 125 6e-29
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 120 2e-27
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 120 2e-27
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 120 2e-27
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 120 2e-27
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 118 9e-27
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 118 9e-27
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 118 9e-27
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 118 9e-27
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 118 9e-27
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 118 9e-27
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 118 9e-27
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 118 9e-27
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens] 118 9e-27
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens] 118 9e-27
gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 116 3e-26
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 115 6e-26
gi|4557859 somatostatin receptor 2 [Homo sapiens] 115 6e-26
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 115 6e-26
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 115 6e-26
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 114 2e-25
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 114 2e-25
gi|149944554 somatostatin receptor 4 [Homo sapiens] 110 1e-24
gi|4503905 galanin receptor 2 [Homo sapiens] 110 2e-24
gi|63477962 opioid receptor, delta 1 [Homo sapiens] 109 3e-24
gi|4557865 somatostatin receptor 5 [Homo sapiens] 107 1e-23
gi|157426873 tachykinin receptor 2 [Homo sapiens] 106 4e-23
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 703 bits (1815), Expect = 0.0
Identities = 350/350 (100%), Positives = 350/350 (100%)
Query: 1 MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN 60
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
Sbjct: 1 MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN 60
Query: 61 AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG 120
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
Sbjct: 61 AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG 120
Query: 121 IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA 180
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
Sbjct: 121 IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA 180
Query: 181 QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM 240
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
Sbjct: 181 QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM 240
Query: 241 FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ 300
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
Sbjct: 241 FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ 300
Query: 301 NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV 350
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Sbjct: 301 NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV 350
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 421 bits (1083), Expect = e-118
Identities = 205/335 (61%), Positives = 257/335 (76%), Gaps = 8/335 (2%)
Query: 3 GNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAG 62
G GSA P+ + RP W+A AL+ VLI T VD++GNLLVILSV RN+KLRNAG
Sbjct: 24 GAGSARPSRTP--------RPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAG 75
Query: 63 NIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIA 122
N+F+VSLA+ADLVVA YPYPL+L++IF +GW LG HC+ S F+MGLSVIGS+FNIT IA
Sbjct: 76 NLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIA 135
Query: 123 INRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQS 182
INRYCYICHS+ Y ++Y ++ ++ LIWLLT+ A+LPN G+L+YDPRIYSCTF Q+
Sbjct: 136 INRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQT 195
Query: 183 VSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFV 242
S+ YT AVVV HFL+P+ +V FCYLRIW+LVLQ R++ KP+ + LKP D R+F+TMFV
Sbjct: 196 ASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFV 255
Query: 243 VFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNF 302
VFV+FAICWAPLN IGLAVA +P M P+IPE LFV SY +AYFNSCLNAI+YGLLNQNF
Sbjct: 256 VFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNF 315
Query: 303 RKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSP 337
R+EY+RI+++L R D+S P+P
Sbjct: 316 RREYKRILLALWNPRHCIQDASKGSHAEGLQSPAP 350
>gi|150170722 G protein-coupled receptor 50 [Homo sapiens]
Length = 617
Score = 347 bits (889), Expect = 1e-95
Identities = 157/307 (51%), Positives = 227/307 (73%), Gaps = 2/307 (0%)
Query: 23 PSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYP 82
P L + C ++ TIVVD++GN +VIL+V +NKKLRN+GNIFVVSL+VAD++VAIYPYP
Sbjct: 24 PPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYP 83
Query: 83 LVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSK 142
L+L ++ GW+L L CQ+ GF+ GLSV+GSIFNI IAINRYCYICHSL+Y++++S +
Sbjct: 84 LMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVR 143
Query: 143 NSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMII 202
N+ Y+++ W++T+ AVLPN+ GT++YDPR Y+C F + +T+ +V HF++P++I
Sbjct: 144 NTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLI 203
Query: 203 VIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVA 262
V FCY+RIW VL R + P + + RNF+TMFV+F+LFA+CW P+N + + VA
Sbjct: 204 VGFCYVRIWTKVLAARD--PAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVA 261
Query: 263 SDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVD 322
P M +IP WL++A+Y++AYFNSCLNA+IYGLLN+NFR+EY I ++ +FF
Sbjct: 262 VSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSG 321
Query: 323 SSNDVAD 329
+D+ +
Sbjct: 322 LISDIRE 328
>gi|167000885 galanin receptor 1 [Homo sapiens]
Length = 349
Score = 125 bits (314), Expect = 6e-29
Identities = 87/285 (30%), Positives = 144/285 (50%), Gaps = 18/285 (6%)
Query: 34 LIFTIVVDILGNLLVILSVYRNK--KLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNN 91
LIF + +LGN LVI + R+K K R+ N+F+++L++ADL ++ P
Sbjct: 42 LIFAL--GVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALP 99
Query: 92 GWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLI 151
W LG C+ + +S++ SIF + ++++RY I HS + L S+N+L V I
Sbjct: 100 TWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCI 159
Query: 152 WLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSV------SSAYTIAVVVFHFLVPMIIVIF 205
W L++A P L + PR + TF AY + VF +L+P++++ F
Sbjct: 160 WALSIAMASPVAYHQGL-FHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICF 218
Query: 206 CYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDP 265
CY + VL + + K + + T+ VV V+F I W P + I L
Sbjct: 219 CYAK----VLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGV 274
Query: 266 ASMVPRIPEWLF-VASYYMAYFNSCLNAIIYGLLNQNFRKEYRRI 309
+ P +LF + ++ +AY NS +N IIY L++NFRK Y+++
Sbjct: 275 FPLTP--ASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQV 317
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 120 bits (301), Expect = 2e-27
Identities = 81/294 (27%), Positives = 153/294 (52%), Gaps = 19/294 (6%)
Query: 33 VLIFTIVV--DILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFN 90
VL++++VV ++GN L++L + R ++L N N + +LA++D+++ PL L F
Sbjct: 64 VLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFE 123
Query: 91 -NGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVL 149
GW G C + FL ++V S+F +T IA++RY + H L+ + S + S VL
Sbjct: 124 PRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLR--RRISLRLSAYAVL 181
Query: 150 LIWLLTLAAVLP----NLRAGTLQYDPRIYSCTFA--QSVSSAYTIAVVVFHFLVPMIIV 203
IW L+ LP +D R+ + + Y +++ +L+P++++
Sbjct: 182 AIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVI 241
Query: 204 IFCYLRIWILVLQVRQRVKPDRKPKL-----KPQDFRNFVTMFVVFVLFAICWAPLNFIG 258
+ Y+R+ + ++R RV P + + + R F + VV V+FA+CW PL+
Sbjct: 242 LLSYVRVSV---KLRNRVVPGCVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFN 298
Query: 259 LAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVS 312
L DP ++ P + + +++A ++C N IY L+ +FR+E R+++V+
Sbjct: 299 LLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVA 352
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 120 bits (300), Expect = 2e-27
Identities = 79/301 (26%), Positives = 150/301 (49%), Gaps = 29/301 (9%)
Query: 42 ILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQ 101
++GN +V V RNK + N+F+++LA++DL+V I+ P+ L+ GW G C+
Sbjct: 60 MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCK 119
Query: 102 VSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLP 161
+SG + G+SV S+F + IA++R+ + + K KL + K + +++IW+L + + P
Sbjct: 120 ISGLVQGISVAASVFTLVAIAVDRFQCVVYPFK-PKL-TIKTAFVIIMIIWVLAITIMSP 177
Query: 162 N-------------LRAGTLQYDPRIYSCTF---AQSVSSAYTIAVVVFHFLVPMIIVIF 205
+ +R + +Y C Q + YT + +L P+ +++
Sbjct: 178 SAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVI 237
Query: 206 CYLRIWILVLQV----RQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAV 261
Y RI I + + R ++ + + + + +V +LF + W PL L +
Sbjct: 238 MYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPL--WTLMM 295
Query: 262 ASDPASMVPR----IPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRII-VSLCTA 316
SD A + P I +++ ++++A+ NS +N IIYG N+NFR+ ++ + LC
Sbjct: 296 LSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQK 355
Query: 317 R 317
R
Sbjct: 356 R 356
>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
Length = 522
Score = 120 bits (300), Expect = 2e-27
Identities = 79/301 (26%), Positives = 150/301 (49%), Gaps = 29/301 (9%)
Query: 42 ILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQ 101
++GN +V V RNK + N+F+++LA++DL+V I+ P+ L+ GW G C+
Sbjct: 162 MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCK 221
Query: 102 VSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLP 161
+SG + G+SV S+F + IA++R+ + + K KL + K + +++IW+L + + P
Sbjct: 222 ISGLVQGISVAASVFTLVAIAVDRFQCVVYPFK-PKL-TIKTAFVIIMIIWVLAITIMSP 279
Query: 162 N-------------LRAGTLQYDPRIYSCTF---AQSVSSAYTIAVVVFHFLVPMIIVIF 205
+ +R + +Y C Q + YT + +L P+ +++
Sbjct: 280 SAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVI 339
Query: 206 CYLRIWILVLQV----RQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAV 261
Y RI I + + R ++ + + + + +V +LF + W PL L +
Sbjct: 340 MYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPL--WTLMM 397
Query: 262 ASDPASMVPR----IPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRII-VSLCTA 316
SD A + P I +++ ++++A+ NS +N IIYG N+NFR+ ++ + LC
Sbjct: 398 LSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQK 457
Query: 317 R 317
R
Sbjct: 458 R 458
>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
Length = 423
Score = 120 bits (300), Expect = 2e-27
Identities = 79/301 (26%), Positives = 150/301 (49%), Gaps = 29/301 (9%)
Query: 42 ILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQ 101
++GN +V V RNK + N+F+++LA++DL+V I+ P+ L+ GW G C+
Sbjct: 63 MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCK 122
Query: 102 VSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLP 161
+SG + G+SV S+F + IA++R+ + + K KL + K + +++IW+L + + P
Sbjct: 123 ISGLVQGISVAASVFTLVAIAVDRFQCVVYPFK-PKL-TIKTAFVIIMIIWVLAITIMSP 180
Query: 162 N-------------LRAGTLQYDPRIYSCTF---AQSVSSAYTIAVVVFHFLVPMIIVIF 205
+ +R + +Y C Q + YT + +L P+ +++
Sbjct: 181 SAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVI 240
Query: 206 CYLRIWILVLQV----RQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAV 261
Y RI I + + R ++ + + + + +V +LF + W PL L +
Sbjct: 241 MYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPL--WTLMM 298
Query: 262 ASDPASMVPR----IPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRII-VSLCTA 316
SD A + P I +++ ++++A+ NS +N IIYG N+NFR+ ++ + LC
Sbjct: 299 LSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQK 358
Query: 317 R 317
R
Sbjct: 359 R 359
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 160 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 218
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 219 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 278
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 279 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 338
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 339 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 394
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 395 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 447
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
Length = 418
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
Length = 446
Score = 118 bits (295), Expect = 9e-27
Identities = 78/296 (26%), Positives = 152/296 (51%), Gaps = 18/296 (6%)
Query: 26 LASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPL 83
+ +A+ + +++IV V + GN LV+ + R K++ A NI++ +LA+AD +A P
Sbjct: 67 MITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALAD-ALATSTLPF 125
Query: 84 VLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKN 143
++ W G + C++ + ++ SIF + ++++RY +CH +K + +N
Sbjct: 126 QSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRN 185
Query: 144 SLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAY-----TIAVVVFHFLV 198
+ + W+L+ A LP + T +Y CT S + Y I V +F F++
Sbjct: 186 AKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIM 245
Query: 199 PMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF- 256
P++I+ CY +++L+++ V+ K K ++ R M VV +F +CW P++
Sbjct: 246 PVLIITVCY---GLMILRLKS-VRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIY 301
Query: 257 -IGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIV 311
I A+ + P + + W F + + Y NSCLN ++Y L++NF++ +R +
Sbjct: 302 VIIKALVTIPETTFQTV-SWHFCIA--LGYTNSCLNPVLYAFLDENFKRCFREFCI 354
>gi|223633971 G protein-coupled receptor 83 [Homo sapiens]
Length = 423
Score = 116 bits (291), Expect = 3e-26
Identities = 81/291 (27%), Positives = 144/291 (49%), Gaps = 19/291 (6%)
Query: 36 FTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNL 95
F IV + GN+LV +++N+++ +A ++F+V+LAVAD+++ + P L+ N+ W
Sbjct: 80 FIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIF 139
Query: 96 GYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLT 155
G C VS F S+ S +T IA++R+ I H LK S + Y+ +IW +
Sbjct: 140 GKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLK--PRISITKGVIYIAVIWTMA 197
Query: 156 LAAVLPNL---RAGTLQYDPRIYSCTF-------AQSVSSAYTIAVVVFHFLVPMIIVIF 205
LP+ + T +Y I A +A + +++P++I+
Sbjct: 198 TFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYILPLLIISV 257
Query: 206 CYLRI--WILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVAS 263
Y R+ + + + V ++ L+ + + + +V VLFA+CW PLN L +
Sbjct: 258 AYARVAKKLWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLLL-- 315
Query: 264 DPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLC 314
+S V R L+ A ++ A ++C N IY LN+NFR E + ++ S+C
Sbjct: 316 --SSKVIRTNNALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKALL-SMC 363
>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
Length = 384
Score = 115 bits (288), Expect = 6e-26
Identities = 75/298 (25%), Positives = 145/298 (48%), Gaps = 18/298 (6%)
Query: 23 PSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYP 82
P + LA I++ + GNL +I+ + + K++RN NI +V+L+ +DL+VAI P
Sbjct: 36 PLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLP 95
Query: 83 LVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSK 142
+ + W G C+++ F+ +S+ SIF++ IA+ R+ I + + +++
Sbjct: 96 FTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRP--NNR 153
Query: 143 NSLCYVLLIWLLTLAAVLPNLRAGTLQYDP----------RIYSCTFAQSVSS----AYT 188
++ + +IW+L +A+ LP L + +P Y C F Q S +YT
Sbjct: 154 HAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVC-FDQFPSDSHRLSYT 212
Query: 189 IAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNF-VTMFVVFVLF 247
++V + P+ + CY +I+I + + + R K + + + + + + V F
Sbjct: 213 TLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAF 272
Query: 248 AICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKE 305
A+CW PL + + LF+ + A ++C+N I YG LN+NF+++
Sbjct: 273 AVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRD 330
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 115 bits (288), Expect = 6e-26
Identities = 80/301 (26%), Positives = 142/301 (47%), Gaps = 14/301 (4%)
Query: 28 SALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMS 87
+ L + ++ + GN LVI + R K++ NI++++LA+AD + + P + M
Sbjct: 44 AVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFML-GLPFLAMQ 102
Query: 88 IFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCY 147
+ W G C+V + G++ SIF +T ++I+RY + H +K K + +
Sbjct: 103 VALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMI 162
Query: 148 VLLIWLLTLAAVLP-NLRAGTLQYDPRIYSCTF-----AQSVSSAYTIAVVVFHFLVPMI 201
+ +W ++L +LP + AG SCT + + + + I + FLVP+
Sbjct: 163 TMAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLT 222
Query: 202 IVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAV 261
I+ CYL I I V RV ++ K + + R + +V +F CW P ++
Sbjct: 223 IICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTR---MVSIVVAVFIFCWLPFYIFNVSS 279
Query: 262 ASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFV 321
S S P + + +F + Y NSC N I+Y L+ NF+K ++ + LC +V
Sbjct: 280 VSMAISPTPAL-KGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNV---LCLVKVSGT 335
Query: 322 D 322
D
Sbjct: 336 D 336
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 115 bits (288), Expect = 6e-26
Identities = 76/298 (25%), Positives = 146/298 (48%), Gaps = 21/298 (7%)
Query: 26 LASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVL 85
LA L VLIF + + GN LV V R+K +R NIF+ SLA++DL++ + P+ +
Sbjct: 46 LALVLTGVLIFALA--LFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTM 103
Query: 86 MSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSL 145
+ ++ W G C++ F+ +V+ I +T IA+ R+ + H K Y+++ +
Sbjct: 104 LQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAF 163
Query: 146 CYVLLIWLLTLAAVLP--NLRAGTLQYD---PRIYSCTFAQSVS----SAYTIAVVVFHF 196
+ ++WL+ + P +++ ++YD + + C + S YT ++V F
Sbjct: 164 TMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILF 223
Query: 197 LVPMIIVIFCYLRI----WILVL----QVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFA 248
L+P+++++ Y +I WI V + + K+ + R + M V LFA
Sbjct: 224 LLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFA 283
Query: 249 ICWAPLNFIGLAV--ASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRK 304
+CWAP + + + + ++ + +F + + NS N I+Y +N+NF+K
Sbjct: 284 VCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKK 341
>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
Length = 430
Score = 115 bits (288), Expect = 6e-26
Identities = 80/298 (26%), Positives = 145/298 (48%), Gaps = 24/298 (8%)
Query: 30 LACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIF 89
+A LIF + + +GN LV V +N+ + N+F+++LAV+DL+V I+ P L+
Sbjct: 48 VAYALIFLLCM--VGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNL 105
Query: 90 NNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVL 149
GW C++SG + G+SV S+F + IA+ R+ I H + +KL + + +L +
Sbjct: 106 ITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFR-EKL-TLRKALVTIA 163
Query: 150 LIWLLTLAAVLPNLRAGTLQYDPR------------IYSCTFA---QSVSSAYTIAVVVF 194
+IW L L + P+ T+ + +YSC A + + YT +
Sbjct: 164 VIWALALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSH 223
Query: 195 HFLVPMIIVIFCYLRIWILVLQVRQRVKPDRK---PKLKPQDFRNFVTMFVVFVLFAICW 251
+L P+ +++ Y RI + Q + P+ + R + +V + F + W
Sbjct: 224 IYLAPLALIVVMYARIARKLCQAPGPAPGGEEAADPRASRRRARVVHMLVMVALFFTLSW 283
Query: 252 APLNFIGLAV--ASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYR 307
PL + L + A + + + F ++++A+FNS N IIYG N+NFR+ ++
Sbjct: 284 LPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFRRGFQ 341
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 114 bits (284), Expect = 2e-25
Identities = 81/306 (26%), Positives = 146/306 (47%), Gaps = 22/306 (7%)
Query: 19 DGARPSWLASALACVLIFTIVVDIL------GNLLVILSVYRNKKLRNAGNIFVVSLAVA 72
+G S+ + AC + T+V+ +L GN++V L+V N++LRN N F+VSLA+
Sbjct: 4 NGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAIT 63
Query: 73 DLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHS 132
DL++ + P + + W+ G + C + L + SI N+ I+++RYC +
Sbjct: 64 DLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDP 123
Query: 133 LKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAG------TLQYDPRIYSCTFAQSVSSA 186
L+Y L + ++LIW++++ ++ G T + + C V+
Sbjct: 124 LRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKV--QVNEV 181
Query: 187 YTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKP-QDFRNFVTMFVVFV 245
Y + + F +P++I+ Y RI+ + +R+ K ++ + VT+ V
Sbjct: 182 YGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMG 241
Query: 246 LFAICWAP--LNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFR 303
F ICW P F+ + D A I E L ++ Y NS LN I+Y LN++FR
Sbjct: 242 AFIICWFPYFTAFVYRGLRGDDA-----INEVLEAIVLWLGYANSALNPILYAALNRDFR 296
Query: 304 KEYRRI 309
Y+++
Sbjct: 297 TGYQQL 302
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 114 bits (284), Expect = 2e-25
Identities = 81/306 (26%), Positives = 146/306 (47%), Gaps = 22/306 (7%)
Query: 19 DGARPSWLASALACVLIFTIVVDIL------GNLLVILSVYRNKKLRNAGNIFVVSLAVA 72
+G S+ + AC + T+V+ +L GN++V L+V N++LRN N F+VSLA+
Sbjct: 4 NGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAIT 63
Query: 73 DLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHS 132
DL++ + P + + W+ G + C + L + SI N+ I+++RYC +
Sbjct: 64 DLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDP 123
Query: 133 LKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAG------TLQYDPRIYSCTFAQSVSSA 186
L+Y L + ++LIW++++ ++ G T + + C V+
Sbjct: 124 LRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKV--QVNEV 181
Query: 187 YTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKP-QDFRNFVTMFVVFV 245
Y + + F +P++I+ Y RI+ + +R+ K ++ + VT+ V
Sbjct: 182 YGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMG 241
Query: 246 LFAICWAP--LNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFR 303
F ICW P F+ + D A I E L ++ Y NS LN I+Y LN++FR
Sbjct: 242 AFIICWFPYFTAFVYRGLRGDDA-----INEVLEAIVLWLGYANSALNPILYAALNRDFR 296
Query: 304 KEYRRI 309
Y+++
Sbjct: 297 TGYQQL 302
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 110 bits (276), Expect = 1e-24
Identities = 83/316 (26%), Positives = 150/316 (47%), Gaps = 14/316 (4%)
Query: 4 NGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGN 63
N S+ P ++ + G G + A+ C+ +V ++GN LVI + R K++ A N
Sbjct: 24 NASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATN 83
Query: 64 IFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAI 123
I++++LAVAD + + P V S W G + C+ + GL++ S+F +T +++
Sbjct: 84 IYLLNLAVADELFML-SVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSV 142
Query: 124 NRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLP-NLRAGTL-QYDPRIYSCTFA- 180
+RY + H L+ + L +WL +L LP + A T + +C
Sbjct: 143 DRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQW 202
Query: 181 --QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFV 238
+ S+ + + + FL+P++ + CYL I + V R ++ + + + R +
Sbjct: 203 PHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVL 262
Query: 239 TMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLL 298
+ VVFVL CW P + L V + + S ++Y NSC N I+YG L
Sbjct: 263 MVVVVFVL---CWMPFYVVQLL-----NLFVTSLDATVNHVSLILSYANSCANPILYGFL 314
Query: 299 NQNFRKEYRRIIVSLC 314
+ NFR+ ++R++ C
Sbjct: 315 SDNFRRFFQRVLCLRC 330
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 110 bits (274), Expect = 2e-24
Identities = 90/318 (28%), Positives = 147/318 (46%), Gaps = 17/318 (5%)
Query: 4 NGSALPNASQPVLRGDGARPSWLASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNA 61
N S P A G G W A+ L+F ++ V +GN LV+ + R + +
Sbjct: 2 NVSGCPGAGNASQAGGGG--GWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVST 59
Query: 62 GNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGI 121
N+F+++L VADL + P +GW G L C+ FL+ L++ S F + +
Sbjct: 60 TNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAV 119
Query: 122 AINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQ 181
+++RY I + L +L + +N+L + LIW L+L P L + C A
Sbjct: 120 SLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAW 179
Query: 182 SV--SSAYTIAVVVFHFLVPMIIVIFCYLR----IWILVLQVRQRVKPDRKPKLKPQDFR 235
S A I VF +L+P++++ Y R +W V V R+ K K
Sbjct: 180 SAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAG-SGARRAKRKVTRM- 237
Query: 236 NFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIY 295
+ +V LF +CW P + + L V + R L + S+ ++Y NSC+N I+Y
Sbjct: 238 ----ILIVAALFCLCWMPHHALILCVWFGQFPLT-RATYALRILSHLVSYANSCVNPIVY 292
Query: 296 GLLNQNFRKEYRRIIVSL 313
L++++FRK +R I L
Sbjct: 293 ALVSKHFRKGFRTICAGL 310
>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
Length = 372
Score = 109 bits (273), Expect = 3e-24
Identities = 88/319 (27%), Positives = 152/319 (47%), Gaps = 16/319 (5%)
Query: 6 SALPNASQPVLRGDGARP-SWLASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAG 62
SA P+A GAR S LA A+A +++ V V +LGN+LV+ + R K++ A
Sbjct: 25 SACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTAT 84
Query: 63 NIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIA 122
NI++ +LA+AD +A P W G L C+ + ++ SIF +T ++
Sbjct: 85 NIYIFNLALAD-ALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMS 143
Query: 123 INRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQS 182
++RY +CH +K + + + IW+L +P + + C
Sbjct: 144 VDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFP 203
Query: 183 VSSAY-----TIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNF 237
S Y I V +F F+VP++I+ CY +++L++R V+ K K + R
Sbjct: 204 SPSWYWDTVTKICVFLFAFVVPILIITVCY---GLMLLRLRS-VRLLSGSKEKDRSLRRI 259
Query: 238 VTMFVVFV-LFAICWAPLN-FIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIY 295
M +V V F +CWAP++ F+ + D P + L + + Y NS LN ++Y
Sbjct: 260 TRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLC-IALGYANSSLNPVLY 318
Query: 296 GLLNQNFRKEYRRIIVSLC 314
L++NF++ +R++ C
Sbjct: 319 AFLDENFKRCFRQLCRKPC 337
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 107 bits (268), Expect = 1e-23
Identities = 88/324 (27%), Positives = 157/324 (48%), Gaps = 24/324 (7%)
Query: 20 GARPSWLASALACVLIFTIV--VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVA 77
G PS A A+ +++ +V + GN LVI V R K++ NI++++LAVAD V+
Sbjct: 31 GPAPSAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVAD-VLY 89
Query: 78 IYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDK 137
+ P + + W G + C++ L G++ S+F +T ++++RY + H L +
Sbjct: 90 MLGLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSAR 149
Query: 138 LYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSV---SSAYTIAVVVF 194
+ + W+L+L LP L +Q + + ++ + V + + I V
Sbjct: 150 WRRPRVAKLASAAAWVLSLCMSLPLLVFADVQ-EGGTCNASWPEPVGLWGAVFIIYTAVL 208
Query: 195 HFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVL-FAICWAP 253
F P++++ CYL I + V RV R+ + R M +V VL FA CW P
Sbjct: 209 GFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR-----RSERKVTRMVLVVVLVFAGCWLP 263
Query: 254 ---LNFIGLAVA--SDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRR 308
+N + LAVA +PAS L+ ++Y NSC N ++YG L+ NFR+ +++
Sbjct: 264 FFTVNIVNLAVALPQEPAS------AGLYFFVVILSYANSCANPVLYGFLSDNFRQSFQK 317
Query: 309 IIVSLCTARVFFVDSSNDVADRVK 332
++ + D++ DR++
Sbjct: 318 VLCLRKGSGAKDADATEPRPDRIR 341
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 106 bits (264), Expect = 4e-23
Identities = 74/296 (25%), Positives = 134/296 (45%), Gaps = 16/296 (5%)
Query: 23 PSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYP 82
PSW + A + ++V + GN +VI + ++++R N F+V+LA+ADL +A +
Sbjct: 29 PSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAA 88
Query: 83 LVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSK 142
+ +N W G C ++ SI+++T IA +RY I H + S+
Sbjct: 89 FNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVH--PFQPRLSAP 146
Query: 143 NSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSA------YTIAVVVFHF 196
++ + IWL+ LA P T+ D C A S Y + V+ +
Sbjct: 147 STKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIY 206
Query: 197 LVPMIIVIFCYLRIWILVLQVRQRVKPDRKPK----LKPQDFRNFV-TMFVVFVLFAICW 251
+P+ ++ Y ++ L + +R P + Q + FV TM +V + FAICW
Sbjct: 207 FLPLAVMFVAYS---VIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICW 263
Query: 252 APLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYR 307
P + + + + + +++A +++A ++ N IIY LN FR +R
Sbjct: 264 LPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFR 319
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.142 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,034,610
Number of Sequences: 37866
Number of extensions: 467781
Number of successful extensions: 3022
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 532
Number of HSP's successfully gapped in prelim test: 201
Number of HSP's that attempted gapping in prelim test: 1449
Number of HSP's gapped (non-prelim): 903
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.