Guide to the Human Genome
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Name: MDH1 Sequence: fasta or formatted (334aa) NCBI GI: 5174539
Description:

cytosolic malate dehydrogenase

Referenced in:

TCA Cycle

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.0         30           2
 C cysteine            1.2          4           1
 D aspartate           6.9         23           2
 E glutamate           5.4         18           2
 F phenylalanine       3.6         12           1
 G glycine             6.9         23           1
 H histidine           1.2          4           1
 I isoleucine          6.0         20           2
 K lysine              9.3         31           2
 L leucine             9.6         32           2
 M methionine          2.7          9           2
 N asparagine          4.2         14           1
 P proline             3.9         13           1
 Q glutamine           2.7          9           2
 R arginine            3.0         10           2
 S serine              7.5         25           2
 T threonine           4.2         14           2
 V valine              9.6         32           2
 W tryptophan          1.2          4           1
 Y tyrosine            2.1          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytosolic malate dehydrogenase 
MDH1B                 0.176   malate dehydrogenase 1B, NAD (soluble) 
LDHB                  0.047   L-lactate dehydrogenase B 
LDHAL6A               0.036   lactate dehydrogenase A-like 6A 
LDHAL6A               0.036   lactate dehydrogenase A-like 6A 
LDHA                  0.035   L-lactate dehydrogenase A isoform 1 
LDHC                  0.033   L-lactate dehydrogenase C 
LDHC                  0.033   L-lactate dehydrogenase C 
LDHAL6B               0.027   lactate dehydrogenase A-like 6B 
BZRAP1                0.008   peripheral benzodiazepine receptor-associated prote...
BZRAP1                0.008   peripheral benzodiazepine receptor-associated prote...
SH3RF1                0.008   SH3 domain containing ring finger 1 
SMCR7                 0.005   Smith-Magenis syndrome chromosome region, candidate...
SMCR7                 0.005   Smith-Magenis syndrome chromosome region, candidate ...
NKIRAS1               0.005   kappa B-ras 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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