Guide to the Human Genome
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Search of human proteins with 51036603

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51036603 G-protein gamma-12 subunit [Homo sapiens]
         (72 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51036603 G-protein gamma-12 subunit [Homo sapiens]                 141   1e-34
gi|32698769 guanine nucleotide binding protein (G protein), gamm...   114   2e-26
gi|54114974 guanine nucleotide binding protein (G protein), gamm...    90   4e-19
gi|148922937 guanine nucleotide binding protein (G protein), gam...    87   4e-18
gi|148922892 guanine nucleotide binding protein (G protein), gam...    87   4e-18
gi|4758450 guanine nucleotide binding protein (G protein), gamma...    87   4e-18
gi|6912394 guanine nucleotide binding protein (G protein), gamma...    85   1e-17
gi|15147246 guanine nucleotide binding protein (G protein), gamm...    80   3e-16
gi|4885287 guanine nucleotide binding protein (G protein), gamma...    72   7e-14
gi|63055067 guanine nucleotide binding protein (G protein), gamm...    70   4e-13
gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens]           69   6e-13
gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens]           69   6e-13
gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens]           69   6e-13
gi|239750840 PREDICTED: hypothetical protein XP_002347578 [Homo ...    60   3e-10
gi|239745202 PREDICTED: hypothetical protein XP_002343408 [Homo ...    60   3e-10
gi|4758448 guanine nucleotide binding protein gamma 11 precursor...    60   5e-10
gi|14589849 guanine nucleotide binding protein-gamma transducing...    54   3e-08
gi|21361097 DNAJC25-GNG10 protein [Homo sapiens]                       53   4e-08
gi|11386179 guanine nucleotide binding protein (G protein), gamm...    51   2e-07
gi|7706567 guanine nucleotide binding protein (G protein), gamma...    35   0.010
gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]         32   0.082
gi|28916698 transposon-derived Buster3 transposase-like [Homo sa...    28   1.2  
gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]         28   1.5  
gi|54792146 tripartite motif-containing 47 [Homo sapiens]              27   3.4  
gi|238231453 dual specificity phosphatase 7 [Homo sapiens]             26   7.7  
gi|116008447 CAP-GLY domain containing linker protein 2 isoform ...    26   7.7  
gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2...    26   7.7  
gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo...    26   7.7  
gi|4506507 regulator of G-protein signalling 11 isoform 2 [Homo ...    26   7.7  

>gi|51036603 G-protein gamma-12 subunit [Homo sapiens]
          Length = 72

 Score =  141 bits (356), Expect = 1e-34
 Identities = 72/72 (100%), Positives = 72/72 (100%)

Query: 1  MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSE 60
          MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSE
Sbjct: 1  MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSE 60

Query: 61 NPFKDKKTCIIL 72
          NPFKDKKTCIIL
Sbjct: 61 NPFKDKKTCIIL 72


>gi|32698769 guanine nucleotide binding protein (G protein), gamma
          7 [Homo sapiens]
          Length = 68

 Score =  114 bits (284), Expect = 2e-26
 Identities = 52/67 (77%), Positives = 63/67 (94%)

Query: 6  ASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKD 65
          ++TNNIAQAR+ V+QLR+EA IERIKVSKA++DLMSYCE+HAR+DPLL+G+P SENPFKD
Sbjct: 2  SATNNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFKD 61

Query: 66 KKTCIIL 72
          KK CIIL
Sbjct: 62 KKPCIIL 68


>gi|54114974 guanine nucleotide binding protein (G protein), gamma
          2 [Homo sapiens]
          Length = 71

 Score = 89.7 bits (221), Expect = 4e-19
 Identities = 43/67 (64%), Positives = 57/67 (85%), Gaps = 1/67 (1%)

Query: 7  STNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDK 66
          +T +IAQAR+ V+QL++EA+I+RIKVSKA+ADLM+YCE HA+ DPLL  +P SENPF++K
Sbjct: 5  NTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREK 64

Query: 67 K-TCIIL 72
          K  C IL
Sbjct: 65 KFFCAIL 71


>gi|148922937 guanine nucleotide binding protein (G protein),
          gamma 4 [Homo sapiens]
          Length = 75

 Score = 86.7 bits (213), Expect = 4e-18
 Identities = 39/67 (58%), Positives = 56/67 (83%), Gaps = 1/67 (1%)

Query: 7  STNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDK 66
          ST +I+QAR+ V+QL++EA ++R+KVS+A+ADL++YCE H R DPL+I +P SENPF++K
Sbjct: 9  STTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68

Query: 67 K-TCIIL 72
          K  C IL
Sbjct: 69 KFFCTIL 75


>gi|148922892 guanine nucleotide binding protein (G protein),
          gamma 4 [Homo sapiens]
          Length = 75

 Score = 86.7 bits (213), Expect = 4e-18
 Identities = 39/67 (58%), Positives = 56/67 (83%), Gaps = 1/67 (1%)

Query: 7  STNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDK 66
          ST +I+QAR+ V+QL++EA ++R+KVS+A+ADL++YCE H R DPL+I +P SENPF++K
Sbjct: 9  STTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68

Query: 67 K-TCIIL 72
          K  C IL
Sbjct: 69 KFFCTIL 75


>gi|4758450 guanine nucleotide binding protein (G protein), gamma
          4 [Homo sapiens]
          Length = 75

 Score = 86.7 bits (213), Expect = 4e-18
 Identities = 39/67 (58%), Positives = 56/67 (83%), Gaps = 1/67 (1%)

Query: 7  STNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDK 66
          ST +I+QAR+ V+QL++EA ++R+KVS+A+ADL++YCE H R DPL+I +P SENPF++K
Sbjct: 9  STTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68

Query: 67 K-TCIIL 72
          K  C IL
Sbjct: 69 KFFCTIL 75


>gi|6912394 guanine nucleotide binding protein (G protein), gamma
          3 [Homo sapiens]
          Length = 75

 Score = 84.7 bits (208), Expect = 1e-17
 Identities = 39/61 (63%), Positives = 52/61 (85%)

Query: 7  STNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDK 66
          ST +I QAR+ V+QL++EAS+ RIKVSKA+ADLM+YC+ HA  DPL+  +PTSENPF++K
Sbjct: 9  STMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPTSENPFREK 68

Query: 67 K 67
          K
Sbjct: 69 K 69


>gi|15147246 guanine nucleotide binding protein (G protein), gamma
          8 [Homo sapiens]
          Length = 70

 Score = 80.5 bits (197), Expect = 3e-16
 Identities = 34/63 (53%), Positives = 55/63 (87%), Gaps = 1/63 (1%)

Query: 11 IAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKT-C 69
          IA+AR+TV+QL+LE +I+R+KVS+A+A+L+++CE HA+ DPL+  +P +ENPF+DK+  C
Sbjct: 8  IAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPFRDKRLFC 67

Query: 70 IIL 72
          ++L
Sbjct: 68 VLL 70


>gi|4885287 guanine nucleotide binding protein (G protein), gamma
          5 [Homo sapiens]
          Length = 68

 Score = 72.4 bits (176), Expect = 7e-14
 Identities = 31/67 (46%), Positives = 50/67 (74%)

Query: 6  ASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKD 65
          + ++++A  ++ VQQLRLEA + R+KVS+A+ADL  +C ++A+ DPLL G+ +S NPF+ 
Sbjct: 2  SGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRP 61

Query: 66 KKTCIIL 72
          +K C  L
Sbjct: 62 QKVCSFL 68


>gi|63055067 guanine nucleotide binding protein (G protein), gamma
          10 [Homo sapiens]
          Length = 68

 Score = 70.1 bits (170), Expect = 4e-13
 Identities = 29/58 (50%), Positives = 45/58 (77%)

Query: 15 RRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCIIL 72
          +R V+QL+LEA +ERIKVS+A+A+L  YC ++A  D LL+G+P   NPF++ ++C +L
Sbjct: 11 QRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCALL 68


>gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 34/72 (47%), Positives = 51/72 (70%), Gaps = 3/72 (4%)

Query: 1  MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSE 60
          MSSK A  ++I QA   V+QL++EA I+++K++   ADL+ +C E A++DP L+GIP + 
Sbjct: 1  MSSKVAINSDIGQALWAVEQLQMEAGIDQVKMA---ADLLKFCTEQAKNDPFLVGIPAAT 57

Query: 61 NPFKDKKTCIIL 72
          N FK+KK   IL
Sbjct: 58 NSFKEKKPYAIL 69


>gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 34/72 (47%), Positives = 51/72 (70%), Gaps = 3/72 (4%)

Query: 1  MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSE 60
          MSSK A  ++I QA   V+QL++EA I+++K++   ADL+ +C E A++DP L+GIP + 
Sbjct: 1  MSSKVAINSDIGQALWAVEQLQMEAGIDQVKMA---ADLLKFCTEQAKNDPFLVGIPAAT 57

Query: 61 NPFKDKKTCIIL 72
          N FK+KK   IL
Sbjct: 58 NSFKEKKPYAIL 69


>gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 34/72 (47%), Positives = 51/72 (70%), Gaps = 3/72 (4%)

Query: 1  MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSE 60
          MSSK A  ++I QA   V+QL++EA I+++K++   ADL+ +C E A++DP L+GIP + 
Sbjct: 1  MSSKVAINSDIGQALWAVEQLQMEAGIDQVKMA---ADLLKFCTEQAKNDPFLVGIPAAT 57

Query: 61 NPFKDKKTCIIL 72
          N FK+KK   IL
Sbjct: 58 NSFKEKKPYAIL 69


>gi|239750840 PREDICTED: hypothetical protein XP_002347578 [Homo
          sapiens]
          Length = 68

 Score = 60.5 bits (145), Expect = 3e-10
 Identities = 26/55 (47%), Positives = 40/55 (72%)

Query: 18 VQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCIIL 72
          V+QL+LEA +ERI VS+A+A+L  YC ++A  D LL+G+    NPF + ++C +L
Sbjct: 14 VEQLKLEAGVERINVSQAAAELQQYCMQNACKDALLVGVLAGSNPFWEPRSCALL 68


>gi|239745202 PREDICTED: hypothetical protein XP_002343408 [Homo
          sapiens]
          Length = 68

 Score = 60.5 bits (145), Expect = 3e-10
 Identities = 26/55 (47%), Positives = 40/55 (72%)

Query: 18 VQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCIIL 72
          V+QL+LEA +ERI VS+A+A+L  YC ++A  D LL+G+    NPF + ++C +L
Sbjct: 14 VEQLKLEAGVERINVSQAAAELQQYCMQNACKDALLVGVLAGSNPFWEPRSCALL 68


>gi|4758448 guanine nucleotide binding protein gamma 11 precursor
          [Homo sapiens]
          Length = 73

 Score = 59.7 bits (143), Expect = 5e-10
 Identities = 26/54 (48%), Positives = 39/54 (72%)

Query: 18 VQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCII 71
          V+QLR E  ++R +VSK S ++ +Y EE +  DPL+ GIP  +NPFK+K +C+I
Sbjct: 19 VEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPEDKNPFKEKGSCVI 72


>gi|14589849 guanine nucleotide binding protein-gamma transducing
          activity polypeptide 2 [Homo sapiens]
          Length = 69

 Score = 53.9 bits (128), Expect = 3e-08
 Identities = 25/54 (46%), Positives = 34/54 (62%)

Query: 18 VQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCII 71
          V+QL+ E    RI +SKA  ++  Y E  A +DP L GIP  +NPFK+K  C+I
Sbjct: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEKGGCLI 68


>gi|21361097 DNAJC25-GNG10 protein [Homo sapiens]
          Length = 153

 Score = 53.1 bits (126), Expect = 4e-08
 Identities = 21/52 (40%), Positives = 36/52 (69%)

Query: 21  LRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCIIL 72
           L +  + E +KVS+A+A+L  YC ++A  D LL+G+P   NPF++ ++C +L
Sbjct: 102 LLVATAYETLKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCALL 153


>gi|11386179 guanine nucleotide binding protein (G protein), gamma
          transducing activity polypeptide 1 [Homo sapiens]
          Length = 74

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 1/55 (1%)

Query: 18 VQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKD-KKTCII 71
          V QL+ E ++ER+ VSK   ++  Y EE +  DPL+ GIP  +NPFK+ K  C+I
Sbjct: 19 VDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPEDKNPFKELKGGCVI 73


>gi|7706567 guanine nucleotide binding protein (G protein), gamma
          13 [Homo sapiens]
          Length = 67

 Score = 35.4 bits (80), Expect = 0.010
 Identities = 17/63 (26%), Positives = 32/63 (50%)

Query: 10 NIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTC 69
          ++ Q ++ V+ L+ + + +R   SK   +L+ + E+    DP L       NP+ +K  C
Sbjct: 5  DVPQMKKEVESLKYQLAFQREMASKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVEKGKC 64

Query: 70 IIL 72
           IL
Sbjct: 65 TIL 67


>gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]
          Length = 487

 Score = 32.3 bits (72), Expect = 0.082
 Identities = 15/56 (26%), Positives = 31/56 (55%), Gaps = 1/56 (1%)

Query: 13  QARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKT 68
           + ++ ++  +++    R+K+SK +  L+SY E++   DP L+  P   NP+    T
Sbjct: 257 ELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLP-PDPSNPWLSDDT 311


>gi|28916698 transposon-derived Buster3 transposase-like [Homo
           sapiens]
          Length = 594

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/52 (25%), Positives = 27/52 (51%)

Query: 14  ARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKD 65
           A++ +QQ+ L   +   ++ + S D++    E  ++ PL +GI  +E    D
Sbjct: 132 AQKKLQQVPLSDDVIHSRIDEMSQDILQQVLEDIKASPLKVGIQLAETTDMD 183


>gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]
          Length = 472

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 13/33 (39%), Positives = 22/33 (66%), Gaps = 2/33 (6%)

Query: 23  LEASIER--IKVSKASADLMSYCEEHARSDPLL 53
           L A I+R  +K+SK +  L++Y E++   DPL+
Sbjct: 268 LNAQIDRHCLKMSKVAESLIAYTEQYVEYDPLI 300


>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
          Length = 638

 Score = 26.9 bits (58), Expect = 3.4
 Identities = 14/28 (50%), Positives = 19/28 (67%)

Query: 11  IAQARRTVQQLRLEASIERIKVSKASAD 38
           IAQ+RRTV  ++  A  ER +VS+  AD
Sbjct: 246 IAQSRRTVALIKSAAVAERERVSRLFAD 273


>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
          Length = 419

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 11/25 (44%), Positives = 14/25 (56%)

Query: 39  LMSYCEEHARSDPLLIGIPTSENPF 63
           L S C+ HA S+ L    PT+ N F
Sbjct: 387 LSSPCDNHASSEQLYFSTPTNHNLF 411


>gi|116008447 CAP-GLY domain containing linker protein 2 isoform 1
           [Homo sapiens]
          Length = 1046

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/47 (27%), Positives = 27/47 (57%)

Query: 1   MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHA 47
           +S  TA    + + ++ ++QL  E  +ER +V+KA++ +    +E A
Sbjct: 351 ISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIA 397


>gi|14702162 CAP-GLY domain containing linker protein 2 isoform 2
           [Homo sapiens]
          Length = 1011

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/47 (27%), Positives = 27/47 (57%)

Query: 1   MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHA 47
           +S  TA    + + ++ ++QL  E  +ER +V+KA++ +    +E A
Sbjct: 351 ISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIA 397


>gi|34452688 regulator of G-protein signalling 11 isoform 1 [Homo
           sapiens]
          Length = 467

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 16/62 (25%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 2   SSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSEN 61
           +S+   T +    +R ++  R      R+K S      +S+C +    DPL+ G   S N
Sbjct: 214 ASRVLMTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPS-N 272

Query: 62  PF 63
           P+
Sbjct: 273 PW 274


>gi|4506507 regulator of G-protein signalling 11 isoform 2 [Homo
           sapiens]
          Length = 446

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 16/62 (25%), Positives = 28/62 (45%), Gaps = 1/62 (1%)

Query: 2   SSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSEN 61
           +S+   T +    +R ++  R      R+K S      +S+C +    DPL+ G   S N
Sbjct: 193 ASRVLMTKSADFHKREIEYFRKALGRTRVKSSVCLEAYLSFCGQRGPHDPLVSGCLPS-N 251

Query: 62  PF 63
           P+
Sbjct: 252 PW 253


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.125    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,050,924
Number of Sequences: 37866
Number of extensions: 53272
Number of successful extensions: 199
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 169
Number of HSP's gapped (non-prelim): 29
length of query: 72
length of database: 18,247,518
effective HSP length: 45
effective length of query: 27
effective length of database: 16,543,548
effective search space: 446675796
effective search space used: 446675796
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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