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Search of human proteins with 50659098
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50659098 regeneration associated muscle protease isoform a
[Homo sapiens]
(737 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50659098 regeneration associated muscle protease isoform a [H... 1553 0.0
gi|50659100 regeneration associated muscle protease isoform b [H... 1513 0.0
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 108 2e-23
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 107 4e-23
gi|4503137 chymotrypsin-like [Homo sapiens] 98 3e-20
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 96 2e-19
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 96 2e-19
gi|223942069 enterokinase precursor [Homo sapiens] 93 1e-18
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 92 2e-18
gi|66347875 complement component 1, r subcomponent [Homo sapiens] 91 4e-18
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 91 5e-18
gi|4506115 protein C [Homo sapiens] 90 9e-18
gi|6912724 tolloid-like 2 [Homo sapiens] 90 9e-18
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 89 1e-17
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 89 1e-17
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 89 1e-17
gi|118498350 chymotrypsin B2 [Homo sapiens] 87 4e-17
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 87 4e-17
gi|118498341 chymotrypsin B1 [Homo sapiens] 87 6e-17
gi|22547221 tolloid-like 1 [Homo sapiens] 85 3e-16
gi|7706083 complement component 1, r subcomponent-like precursor... 84 5e-16
gi|148806900 epidermis-specific serine protease-like protein [Ho... 83 1e-15
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 82 2e-15
gi|11415040 matriptase [Homo sapiens] 81 3e-15
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 81 4e-15
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 81 4e-15
gi|29244926 corin [Homo sapiens] 81 4e-15
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 81 4e-15
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 80 5e-15
gi|4503627 coagulation factor XI precursor [Homo sapiens] 80 7e-15
>gi|50659098 regeneration associated muscle protease isoform a [Homo
sapiens]
Length = 737
Score = 1553 bits (4022), Expect = 0.0
Identities = 737/737 (100%), Positives = 737/737 (100%)
Query: 1 MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKRE 60
MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKRE
Sbjct: 1 MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKRE 60
Query: 61 VVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGW 120
VVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGW
Sbjct: 61 VVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGW 120
Query: 121 YGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
YGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD
Sbjct: 121 YGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
Query: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACS 240
YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACS
Sbjct: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACS 240
Query: 241 SSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDP 300
SSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDP
Sbjct: 241 SSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDP 300
Query: 301 GGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI 360
GGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI
Sbjct: 301 GGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI 360
Query: 361 KACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGY 420
KACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGY
Sbjct: 361 KACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGY 420
Query: 421 QHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWP 480
QHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWP
Sbjct: 421 QHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWP 480
Query: 481 WQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVV 540
WQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVV
Sbjct: 481 WQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVV 540
Query: 541 LGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAA 600
LGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAA
Sbjct: 541 LGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAA 600
Query: 601 SRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSV 660
SRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSV
Sbjct: 601 SRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSV 660
Query: 661 TDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLST 720
TDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLST
Sbjct: 661 TDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLST 720
Query: 721 AFTKVLPFKDWIERNMK 737
AFTKVLPFKDWIERNMK
Sbjct: 721 AFTKVLPFKDWIERNMK 737
>gi|50659100 regeneration associated muscle protease isoform b [Homo
sapiens]
Length = 720
Score = 1513 bits (3917), Expect = 0.0
Identities = 720/737 (97%), Positives = 720/737 (97%), Gaps = 17/737 (2%)
Query: 1 MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKRE 60
MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKRE
Sbjct: 1 MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKRE 60
Query: 61 VVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGW 120
VVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGW
Sbjct: 61 VVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGW 120
Query: 121 YGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
YGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD
Sbjct: 121 YGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
Query: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACS 240
YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACS
Sbjct: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACS 240
Query: 241 SSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDP 300
SSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLE ERNCSDP
Sbjct: 241 SSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLE-----------------ERNCSDP 283
Query: 301 GGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI 360
GGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI
Sbjct: 284 GGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI 343
Query: 361 KACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGY 420
KACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGY
Sbjct: 344 KACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGY 403
Query: 421 QHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWP 480
QHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWP
Sbjct: 404 QHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWP 463
Query: 481 WQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVV 540
WQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVV
Sbjct: 464 WQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVV 523
Query: 541 LGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAA 600
LGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAA
Sbjct: 524 LGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAA 583
Query: 601 SRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSV 660
SRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSV
Sbjct: 584 SRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSV 643
Query: 661 TDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLST 720
TDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLST
Sbjct: 644 TDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLST 703
Query: 721 AFTKVLPFKDWIERNMK 737
AFTKVLPFKDWIERNMK
Sbjct: 704 AFTKVLPFKDWIERNMK 720
>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
precursor [Homo sapiens]
Length = 699
Score = 108 bits (269), Expect = 2e-23
Identities = 91/335 (27%), Positives = 148/335 (44%), Gaps = 57/335 (17%)
Query: 425 TQLQYECISPFYRRLGSSRR--TCLRTGKWSGRA-----PSCIPICG----------KIE 467
++++Y C P+Y+ L ++ TC G W + P+C+P+CG +I
Sbjct: 391 SEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPVCGLPKFSRKLMARIF 450
Query: 468 NITAPKTQGLRWPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTD-- 525
N P +G PW A + S G F C G+L+ +V AAHC+
Sbjct: 451 N-GRPAQKGTT-PWIAML----------SHLNGQPF--CGGSLLGSSWIVTAAHCLHQSL 496
Query: 526 ------LGKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIA 579
L ++ +D K++LGK +R R ++ Q L + LHP YDP + D+A
Sbjct: 497 DPEDPTLRDSDLLSPSDFKIILGKHWRL--RSDENEQHLGVKHTTLHPQYDPNTFENDVA 554
Query: 580 ILKLLDKARISTRVQPICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVV 639
+++LL+ ++ V PICL + + + V+GW R P +TL +
Sbjct: 555 LVELLESPVLNAFVMPICLPE----GPQQEGAMVIVSGWGKQFLQRFP----ETLMEIEI 606
Query: 640 SVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPR 699
+VD C++ + + VT +M CA E D C ++GG R +
Sbjct: 607 PIVDHSTCQKAYAP--LKKKVTRDMICAG-EKEGGKDACAGDSGGPMVTLNRERG----Q 659
Query: 700 WHLMGLVSWSYDKTCSHRLSTAFTKVLPFKDWIER 734
W+L+G VSW D R ++ + KDWI+R
Sbjct: 660 WYLVGTVSWGDDCGKKDRYG-VYSYIHHNKDWIQR 693
Score = 63.5 bits (153), Expect = 7e-10
Identities = 46/140 (32%), Positives = 64/140 (45%), Gaps = 20/140 (14%)
Query: 142 ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGN 201
+SYP ++ W I GF I+L F+ +LE Y+C+YDYV+V D Q++ CG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED----QVLATFCGR 93
Query: 202 E----RPAPIQSI----GSSLHVLFHSDGS--KNFDGFHAIY-----EEITACSSSPCFH 246
E P Q + GS + + F SD S + F GF A Y +E
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSC 153
Query: 247 DGTCVLDKAGSYKCACLAGY 266
D C + G Y C+C GY
Sbjct: 154 DHYC-HNYIGGYYCSCRFGY 172
Score = 62.0 bits (149), Expect = 2e-09
Identities = 69/302 (22%), Positives = 119/302 (39%), Gaps = 44/302 (14%)
Query: 107 YVKGFYCAECRAGWY----GGDC-MRCGQVLRAPKGQILLES-----YPLNAHCEWTIHA 156
Y+ G+YC+ CR G+ C + C L + ++ YP ++ C +TI
Sbjct: 160 YIGGYYCS-CRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIEL 218
Query: 157 KPGFVIQLRFVMLSLEFDYM---CQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSS 213
+ GF++ L+F + D+ C YDY++++ G +++ CG + P PI + S
Sbjct: 219 EEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHS 274
Query: 214 LHVLFHSDGSKNFDGFHAIYEEI-TACSS-SPCFHDGTCVLDKAGSYK----CACLAGYT 267
+ +LFHSD S G+ Y C P H +K +C GY
Sbjct: 275 VLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGY- 333
Query: 268 GQRCENLLEAGKSKIKASED-----SLSVLEERNCSDPGGPVNGYQKITGGPGLINGRHA 322
+ ++ +E +I+ +D + + +C PG +G + L +
Sbjct: 334 -KVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYK-- 390
Query: 323 KIGTVVSFFCNNSYVLSGNEKR---TCQQNGEWSGK-----QPICIKACREPKISDLVRR 374
+ + + C Y N TC G W K P C+ C PK S +
Sbjct: 391 ---SEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPVCGLPKFSRKLMA 447
Query: 375 RV 376
R+
Sbjct: 448 RI 449
>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
precursor [Homo sapiens]
Length = 728
Score = 107 bits (267), Expect = 4e-23
Identities = 94/341 (27%), Positives = 157/341 (46%), Gaps = 45/341 (13%)
Query: 425 TQLQYECISPFYRRLGSSRR--TCLRTGKWSGRA-----PSCIPICGK--------IENI 469
++++Y C P+Y+ L ++ TC G W + P+C+P CG+ ++ I
Sbjct: 391 SEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRI 450
Query: 470 TAPKTQ--GLRWPWQAAIYRRTSGVHDGS-LHKGAWFLVCSGALVNERTVVVAAHCVTDL 526
+ GL +PWQA I V D S + WF SGAL++ ++ AAH +
Sbjct: 451 IGGRNAEPGL-FPWQALIV-----VEDTSRVPNDKWF--GSGALLSASWILTAAHVLRSQ 502
Query: 527 GKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDK 586
+ T + + V D RD+ + + ++LHP+++ + DIA+++L +
Sbjct: 503 RRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEP 562
Query: 587 ARISTRVQPICLAASRDLSTSFQESHI--TVAGWNV------LADVRSPGFK--NDTLRS 636
+ V P+CL L H+ VAGW + + ++ S G + +D L+
Sbjct: 563 VPLGPHVMPVCLPR---LEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQY 619
Query: 637 GVVSVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASP 696
+ VV C+ +E SVT+NMFCA + D C ++GG A V F +
Sbjct: 620 VKLPVVPHAECKTSYESRSGNYSVTENMFCAGYY-EGGKDTCLGDSGG-AFVIFDDLSQ- 676
Query: 697 EPRWHLMGLVSWSYDKTC-SHRLSTAFTKVLPFKDWIERNM 736
RW + GLVSW + C S ++ +TKV + DW+ M
Sbjct: 677 --RWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQM 715
Score = 63.5 bits (153), Expect = 7e-10
Identities = 46/140 (32%), Positives = 64/140 (45%), Gaps = 20/140 (14%)
Query: 142 ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGN 201
+SYP ++ W I GF I+L F+ +LE Y+C+YDYV+V D Q++ CG
Sbjct: 38 DSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED----QVLATFCGR 93
Query: 202 E----RPAPIQSI----GSSLHVLFHSDGS--KNFDGFHAIY-----EEITACSSSPCFH 246
E P Q + GS + + F SD S + F GF A Y +E
Sbjct: 94 ETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSC 153
Query: 247 DGTCVLDKAGSYKCACLAGY 266
D C + G Y C+C GY
Sbjct: 154 DHYC-HNYIGGYYCSCRFGY 172
Score = 60.1 bits (144), Expect = 7e-09
Identities = 69/302 (22%), Positives = 120/302 (39%), Gaps = 46/302 (15%)
Query: 107 YVKGFYCAECRAGWY----GGDC-MRCGQVLRAPKGQILLES-----YPLNAHCEWTIHA 156
Y+ G+YC+ CR G+ C + C L + ++ YP ++ C +TI
Sbjct: 160 YIGGYYCS-CRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIEL 218
Query: 157 KPGFVIQLRFVMLSLEFDYM---CQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSS 213
+ GF++ L+F + D+ C YDY++++ G +++ CG + P PI + S
Sbjct: 219 EEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGP----KVLGPFCGEKAPEPISTQSHS 274
Query: 214 LHVLFHSDGSKNFDGFHAIYEEI-TACSS-SPCFHDGTCVLDKAGSYK----CACLAGYT 267
+ +LFHSD S G+ Y C P H +K +C GY
Sbjct: 275 VLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGY- 333
Query: 268 GQRCENLLEAGKSKIKASED-----SLSVLEERNCSDPGGPVNGYQKITGGPGLINGRHA 322
+ ++ +E +I+ +D + + +C PG +G + L +
Sbjct: 334 -KVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYK-- 390
Query: 323 KIGTVVSFFCNNSYVLSGNEKR---TCQQNGEWSGK-----QPICIKACREP--KISDLV 372
+ + + C Y N TC G W K P C+ C +P + LV
Sbjct: 391 ---SEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQPSRSLPSLV 447
Query: 373 RR 374
+R
Sbjct: 448 KR 449
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 97.8 bits (242), Expect = 3e-20
Identities = 73/256 (28%), Positives = 119/256 (46%), Gaps = 41/256 (16%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQ ++ + +SG H C G+L+++ VV AAHC G+
Sbjct: 45 WPWQVSL-QDSSGFH-----------FCGGSLISQSWVVTAAHCNVSPGRHF-------- 84
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
VVLG++ R + + +Q L +S I HP+++ ++ D+ +LKL A+ +TR+ P+CL
Sbjct: 85 VVLGEYDRSSNAEP--LQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTTRISPVCL 142
Query: 599 AASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPV 658
A+S + T + GW L+ V + L+ + +V C +
Sbjct: 143 ASSNEALT--EGLTCVTTGWGRLSGVGN--VTPAHLQQVALPLVTVNQCRQYWGS----- 193
Query: 659 SVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRL 718
S+TD+M CA A + C ++GG P W L+G+VSW K C+ R
Sbjct: 194 SITDSMICAG---GAGASSCQGDSGG------PLVCQKGNTWVLIGIVSWG-TKNCNVRA 243
Query: 719 STAFTKVLPFKDWIER 734
+T+V F WI +
Sbjct: 244 PAVYTRVSKFSTWINQ 259
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 95.5 bits (236), Expect = 2e-19
Identities = 81/258 (31%), Positives = 115/258 (44%), Gaps = 49/258 (18%)
Query: 480 PWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKV 539
P+QAA+Y TSG L+C G L++ V+ AAHC K +L+V
Sbjct: 34 PYQAALY--TSG-----------HLLCGGVLIHPLWVLTAAHC----------KKPNLQV 70
Query: 540 VLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLA 599
LGK + R+ QS + A+I HP+YD D DI +L+L A++S +QP+ L
Sbjct: 71 FLGK-HNLRQRESSQEQSSVVRAVI-HPDYDAASHDQDIMLLRLARPAKLSELIQPLPL- 127
Query: 600 ASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVS 659
RD S + HI GW AD P DT++ + +V CE H P
Sbjct: 128 -ERDCSANTTSCHI--LGWGKTADGDFP----DTIQCAYIHLVSREECE-----HAYPGQ 175
Query: 660 VTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLS 719
+T NM CA E D C ++GG HL GLVSW S
Sbjct: 176 ITQNMLCAGDEKYG-KDSCQGDSGGPLVCGD----------HLRGLVSWGNIPCGSKEKP 224
Query: 720 TAFTKVLPFKDWIERNMK 737
+T V + +WI++ ++
Sbjct: 225 GVYTNVCRYTNWIQKTIQ 242
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 95.5 bits (236), Expect = 2e-19
Identities = 81/258 (31%), Positives = 115/258 (44%), Gaps = 49/258 (18%)
Query: 480 PWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKV 539
P+QAA+Y TSG L+C G L++ V+ AAHC K +L+V
Sbjct: 34 PYQAALY--TSG-----------HLLCGGVLIHPLWVLTAAHC----------KKPNLQV 70
Query: 540 VLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLA 599
LGK + R+ QS + A+I HP+YD D DI +L+L A++S +QP+ L
Sbjct: 71 FLGK-HNLRQRESSQEQSSVVRAVI-HPDYDAASHDQDIMLLRLARPAKLSELIQPLPL- 127
Query: 600 ASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVS 659
RD S + HI GW AD P DT++ + +V CE H P
Sbjct: 128 -ERDCSANTTSCHI--LGWGKTADGDFP----DTIQCAYIHLVSREECE-----HAYPGQ 175
Query: 660 VTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLS 719
+T NM CA E D C ++GG HL GLVSW S
Sbjct: 176 ITQNMLCAGDEKYG-KDSCQGDSGGPLVCGD----------HLRGLVSWGNIPCGSKEKP 224
Query: 720 TAFTKVLPFKDWIERNMK 737
+T V + +WI++ ++
Sbjct: 225 GVYTNVCRYTNWIQKTIQ 242
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 92.8 bits (229), Expect = 1e-18
Identities = 131/591 (22%), Positives = 221/591 (37%), Gaps = 120/591 (20%)
Query: 143 SYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE 202
SYP A C W ++A+ G IQL F EFD D VE+RDG+ D ++ G
Sbjct: 545 SYPNLAFCVWILNAQKGKNIQLHFQ----EFDLENINDVVEIRDGEEADSLLLAVYTGPG 600
Query: 203 RPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGSYKCAC 262
+ S + + VL ++ GF A + + +H G KA ++C
Sbjct: 601 PVKDVFSTTNRMTVLLITNDVLARGGFKANF--------TTGYHLGIPEPCKADHFQCK- 651
Query: 263 LAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDPGGPVNGYQKITGGPGLINGRHA 322
C L+ + + S +E +C V + T GL+ R
Sbjct: 652 -----NGECVPLVNLCDGHLHCEDGS----DEADC------VRFFNGTTNNNGLVRFRIQ 696
Query: 323 KIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKACREPKISDLVRRRVLPMQVQ 382
I C +N +C ++L +
Sbjct: 697 SIWHTA-----------------CAENWTTQISNDVC---------------QLLGLGSG 724
Query: 383 SRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGYQHLHTQLQYECISPFYRRLGSS 442
+ P+ F K L +AP HL +C+ RL +
Sbjct: 725 NSSKPIFSTDGGPFVK--LNTAPDG--------------HLILTPSQQCLQDSLIRLQCN 768
Query: 443 RRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWPWQAAIYRRTSGVHDGSLHKGAW 502
++C G+ + I KI + K WPW +Y + G L
Sbjct: 769 HKSC-------GKKLAAQDITPKIVGGSNAKEGA--WPWVVGLY------YGGRL----- 808
Query: 503 FLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISA 562
+C +LV+ +V AAHCV ++ + +LG + + +T+ L I
Sbjct: 809 --LCGASLVSSDWLVSAAHCVYGRN----LEPSKWTAILGLHMKSNLTSPQTVPRL-IDE 861
Query: 563 IILHPNYDPILLDADIAILKLLDKARISTRVQPICLAASRDLSTSFQESHITVAGWNVLA 622
I+++P+Y+ D DIA++ L K + +QPICL + + + ++AGW
Sbjct: 862 IVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGR--NCSIAGWGT-- 917
Query: 623 DVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICTAET 682
V G + L+ V ++ + C++Q ++ ++T+NM CA +E D C ++
Sbjct: 918 -VVYQGTTANILQEADVPLLSNERCQQQMPEY----NITENMICAGYE-EGGIDSCQGDS 971
Query: 683 GGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLSTAFTKVLPFKDWIE 733
GG P RW L G+ S+ Y +R + +V F +WI+
Sbjct: 972 GG------PLMCQENNRWFLAGVTSFGYKCALPNR-PGVYARVSRFTEWIQ 1015
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 91.7 bits (226), Expect = 2e-18
Identities = 146/661 (22%), Positives = 226/661 (34%), Gaps = 173/661 (26%)
Query: 107 YVKGFYCAECRAGWY------GGDCMRCGQVLRAPKGQILLESYPLN----AHCEWTIHA 156
++ GFYC+ CRAG+ + GQV G++ YP + C ++I
Sbjct: 159 HLGGFYCS-CRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPEYPRPYPKLSSCTYSISL 217
Query: 157 KPGFVIQLRFVM---LSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSS 213
+ GF + L FV + + +C YD+++++ G CG P I++ ++
Sbjct: 218 EEGFSVILDFVESFDVETHPETLCPYDFLKIQTDREEHGPF----CGKTLPHRIETKSNT 273
Query: 214 LHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQRCEN 273
+ + T V D++G + TG +
Sbjct: 274 VTI--------------------------------TFVTDESGDH--------TGWKIHY 293
Query: 274 LLEAGKSKIKASEDSLSVLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCN 333
A + C P P NG+ ++ S FC
Sbjct: 294 TSTA-----------------QPCPYPMAPPNGHVSPVQAKYILKDSF-------SIFCE 329
Query: 334 NSYVLSGNE------KRTCQQNGEWSGKQPIC-IKACREPKISDLVRRRVLPMQVQSRET 386
Y L CQ++G W P C I C P DL RV
Sbjct: 330 TGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPP--DDLPSGRV---------- 377
Query: 387 PLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGYQHLHTQLQYECISPFYR-RLGSSRRT 445
+ + P G +QY C FY ++ +
Sbjct: 378 -------------EYITGP-------------GVTTYKAVIQYSCEETFYTMKVNDGKYV 411
Query: 446 CLRTGKWSGRA-----PSCIPICGKIENITAPKTQGLR------WPWQAAIYRRTSGVHD 494
C G W+ P C P+CG T + G + +PWQ I T+
Sbjct: 412 CEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQKAKPGDFPWQVLILGGTTA--- 468
Query: 495 GSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRDEKT 554
+GAL+ + V+ AAH V + + L + +G R +
Sbjct: 469 ------------AGALLYDNWVLTAAHAVYEQKH----DASALDIRMGTLKRLSPHYTQA 512
Query: 555 IQSLQISAIILHPNYDPIL-LDADIAILKLLDKARISTRVQPICLAASRDLSTSFQESHI 613
A+ +H Y D DIA++KL +K I++ + PICL S +
Sbjct: 513 WSE----AVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIG 568
Query: 614 TVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIP-VSVTDNMFCASWEPT 672
T +GW + GF L + +VD C +E P SVT NM CA E +
Sbjct: 569 TASGWG----LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAGLE-S 623
Query: 673 APSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLSTAFTKVLPFKDWI 732
D C ++GG A+ F S RW + G+VSW +TKV+ + WI
Sbjct: 624 GGKDSCRGDSGG--ALVF--LDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWI 679
Query: 733 E 733
E
Sbjct: 680 E 680
Score = 70.5 bits (171), Expect = 5e-12
Identities = 47/136 (34%), Positives = 68/136 (50%), Gaps = 24/136 (17%)
Query: 152 WTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE----RPAP- 206
WT+ A PG+ ++L F LE ++C+YD+V++ G +++ +CG E AP
Sbjct: 47 WTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSG----AKVLATLCGQESTDTERAPG 102
Query: 207 ---IQSIGSSLHVLFHSDGS--KNFDGFHAIY--EEITACSSSP-----CFHDGTCVLDK 254
S+GSSL + F SD S K F GF A Y E+I C +P C H +
Sbjct: 103 KDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAPTCDHH---CHNH 159
Query: 255 AGSYKCACLAGYTGQR 270
G + C+C AGY R
Sbjct: 160 LGGFYCSCRAGYVLHR 175
>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
Length = 705
Score = 90.9 bits (224), Expect = 4e-18
Identities = 109/442 (24%), Positives = 165/442 (37%), Gaps = 113/442 (25%)
Query: 332 CNNSY-VLSGNE-----KRTCQQNGEWSGKQPIC-IKACREPKISDLVRRRVLPMQVQSR 384
C Y ++ GN+ CQ +G W P C IK C +P+
Sbjct: 338 CKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPR----------------- 380
Query: 385 ETPLHQLYSAAFSKQKLQSAPTKKPALPFGDL----PMGYQHLHTQLQYECISPFYR--- 437
LP GD MG ++QY C P+Y+
Sbjct: 381 -------------------------NLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQT 415
Query: 438 RLGSSRR-----TCLRTGKWSG-----RAPSCIPICGKIEN--------ITAPKTQGLRW 479
R GS TC G W + P C+P+CGK N I K + +
Sbjct: 416 RAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNF 475
Query: 480 PWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKV 539
PWQ + +H GAL+ +R ++ AAH + A L V
Sbjct: 476 PWQVF-----TNIHGRG----------GGALLGDRWILTAAHTLYPKEHEAQ-SNASLDV 519
Query: 540 VLGKFYRDDDRDEKTIQSLQISAIILHPNY---DPILLDADIAILKLLDKARISTRVQPI 596
LG + + + + I + +HP+Y + + DIA+L+L + + + PI
Sbjct: 520 FLG---HTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPI 576
Query: 597 CLAASRDLSTSFQESHIT-VAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHG 655
CL D T + + V+G+ V+ + + LR + V + CE
Sbjct: 577 CLP---DNDTFYDLGLMGYVSGFGVMEEKIA-----HDLRFVRLPVANPQACENWLRGKN 628
Query: 656 IPVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCS 715
+ NMFCA P+ D C ++GG+ AV P RW G+VSW CS
Sbjct: 629 RMDVFSQNMFCAG-HPSLKQDACQGDSGGVFAVRDPNT----DRWVATGIVSWGIG--CS 681
Query: 716 HRLSTAFTKVLPFKDWIERNMK 737
+TKVL + DWI++ M+
Sbjct: 682 RGYGF-YTKVLNYVDWIKKEME 702
Score = 55.5 bits (132), Expect = 2e-07
Identities = 66/308 (21%), Positives = 122/308 (39%), Gaps = 47/308 (15%)
Query: 107 YVKGFYCAECRAGW------YGGDCMRCGQVLRAPKGQILL----ESYPLNAHCEWTIHA 156
YV G++C+ CR G+ + ++ G I SYP + C ++I
Sbjct: 168 YVGGYFCS-CRPGYELQEDRHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRV 226
Query: 157 KPGFVIQLRFVMLSLEFDYM---CQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSS 213
+ G + L+F+ D+ C YD +++ +G+ I CG +RP + + ++
Sbjct: 227 ERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIY----ANGKNIGEFCGKQRPPDLDTSSNA 282
Query: 214 LHVLFHSDGSKNFDGFHAIY-EEITACSSSPCFHDGTCVLDKAGSYK------CACLAGY 266
+ +LF +D S + G+ Y EI C + T + + Y+ C GY
Sbjct: 283 VDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGY 342
Query: 267 ---TGQRCENLLEAGKSKIKASEDSLSVLEERNCSDPGGPVNGYQKITGGPGLINGRHAK 323
G + + A ++ + ++C P NG + T G +N A+
Sbjct: 343 QLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMG-VNTYKAR 401
Query: 324 IGTVVSFFCNNSY----VLSGNEKR-----TCQQNGEWSGKQ-----PICIKACREPKIS 369
I ++C+ Y +G+ + TC G W +Q P C+ C +P
Sbjct: 402 I----QYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNP 457
Query: 370 DLVRRRVL 377
R+R++
Sbjct: 458 VEQRQRII 465
Score = 39.7 bits (91), Expect = 0.010
Identities = 41/162 (25%), Positives = 65/162 (40%), Gaps = 36/162 (22%)
Query: 144 YPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNER 203
YP N I G+ ++L F LE C YDYV++ + D + + R CG +
Sbjct: 38 YPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKI----SADKKSLGRFCG-QL 92
Query: 204 PAPI---------QSIGSSLHVLFHSDGSKN-------FDGFHAIYE--EITACSS---- 241
+P+ S G+ + + FH+D S + GF A Y+ ++ C+S
Sbjct: 93 GSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKL 152
Query: 242 ------SPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEA 277
C H + G Y C+C GY Q + +A
Sbjct: 153 GEEDPQPQCQH---LCHNYVGGYFCSCRPGYELQEDRHSCQA 191
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 90.5 bits (223), Expect = 5e-18
Identities = 74/261 (28%), Positives = 116/261 (44%), Gaps = 27/261 (10%)
Query: 480 PWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKV 539
PWQ ++R K L+C +L+++R V+ AAHC+ DL V
Sbjct: 376 PWQVMLFR-----------KSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLV 424
Query: 540 VLGKFYRDDDRDEKTIQSL-QISAIILHPNYD-PILLDADIAILKLLDKARISTRVQPIC 597
+GK R R E+ I+ + + I +HP Y+ LD DIA++KL S + P+C
Sbjct: 425 RIGKHSR--TRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 482
Query: 598 LAASRDLSTSFQESHI-TVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGI 656
L ++ Q + V GW L + + + V+ VV+ + E
Sbjct: 483 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKG--QPSVLQVVNLPIVERPVCKDST 540
Query: 657 PVSVTDNMFCASWEPT--APSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTC 714
+ +TDNMFCA ++P D C ++GG F ++ RW+ MG+VSW + C
Sbjct: 541 RIRITDNMFCAGYKPDEGKRGDACEGDSGG----PFVMKSPFNNRWYQMGIVSWG--EGC 594
Query: 715 SHRLSTAF-TKVLPFKDWIER 734
F T V K WI++
Sbjct: 595 DRDGKYGFYTHVFRLKKWIQK 615
>gi|4506115 protein C [Homo sapiens]
Length = 461
Score = 89.7 bits (221), Expect = 9e-18
Identities = 73/238 (30%), Positives = 107/238 (44%), Gaps = 27/238 (11%)
Query: 504 LVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISAI 563
L C L++ V+ AAHC+ + K L V LG++ D R EK L I +
Sbjct: 236 LACGAVLIHPSWVLTAAHCMDESKK--------LLVRLGEY--DLRRWEKWELDLDIKEV 285
Query: 564 ILHPNYDPILLDADIAILKLLDKARISTRVQPICL----AASRDLSTSFQESHITVAGWN 619
+HPNY D DIA+L L A +S + PICL A R+L+ + QE+ +T G++
Sbjct: 286 FVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYH 345
Query: 620 VLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICT 679
+ + + L + VV C E + V++NM CA D C
Sbjct: 346 SSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSN-----MVSENMLCAGILGDR-QDACE 399
Query: 680 AETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRLSTAFTKVLPFKDWIERNMK 737
++GG SF G W L+GLVSW H +TKV + DWI +++
Sbjct: 400 GDSGGPMVASFHG------TWFLVGLVSWGEGCGLLHNYG-VYTKVSRYLDWIHGHIR 450
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 193 QIIKRVCGNERPAPI-QSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCV 251
+ I+ +C E I Q++ +L + SK+ DG + + +S C GTC+
Sbjct: 58 ECIEEICDFEEAKEIFQNVDDTL-----AFWSKHVDGDQCLVLPLEHPCASLCCGHGTCI 112
Query: 252 LDKAGSYKCACLAGYTGQRCE 272
D GS+ C C +G+ G+ C+
Sbjct: 113 -DGIGSFSCDCRSGWEGRFCQ 132
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 89.7 bits (221), Expect = 9e-18
Identities = 57/156 (36%), Positives = 76/156 (48%), Gaps = 11/156 (7%)
Query: 119 GWYGGDCMRCGQVLRAPKGQILLESYP----LNAHCEWTIHAKPGFVIQLRFVMLSLEFD 174
G++ CG + GQI +YP + C W I GF + L F +E
Sbjct: 455 GFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERH 514
Query: 175 YMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA-IY 233
C YDY+EVRDG + +I CG E+P ++S + L + F SDGS N GF A +
Sbjct: 515 DSCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFF 574
Query: 234 EEITACS---SSPCFHDGTCVLDKAGSYKCACLAGY 266
+E+ CS C H CV + GSYKCAC GY
Sbjct: 575 KEVDECSWPDHGGCEH--RCV-NTLGSYKCACDPGY 607
Score = 81.6 bits (200), Expect = 2e-15
Identities = 55/157 (35%), Positives = 84/157 (53%), Gaps = 14/157 (8%)
Query: 142 ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGN 201
+ YP N +C W + A + I L+F + LE + +C+YD+VEVR G + D ++ R CG+
Sbjct: 638 KEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGS 697
Query: 202 ERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIY---EEITACSSSPCFHDGTCVLDKAGSY 258
E P I S +++ V F SD + + GF A + ++ A + C H+ CV + GSY
Sbjct: 698 ETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDNGGCQHE--CV-NTFGSY 754
Query: 259 KCACLAGY----TGQRCENLLEAG-KSKIKASEDSLS 290
C C GY G C+ EAG KI + E +L+
Sbjct: 755 LCRCRNGYWLHENGHDCK---EAGCAHKISSVEGTLA 788
Score = 77.8 bits (190), Expect = 3e-14
Identities = 44/114 (38%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 125 CMRCGQVLRAPKGQILL----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
C CG+ L+ G YP +HC W I PG I L F + L +C YD
Sbjct: 348 CPACGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYD 407
Query: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYE 234
YVEVRDG R ++ R CG++ P P+ S S L V F S + GF A YE
Sbjct: 408 YVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE 461
Score = 75.5 bits (184), Expect = 2e-13
Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 10/156 (6%)
Query: 88 FENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWY----GGDCMR--CGQVLRAPKGQILL 141
F + C + G + G Y CR G++ G DC C + + +G +
Sbjct: 730 FSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLAS 789
Query: 142 ----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKR 197
+ YP C W I + G ++L F +E C YD++E+ DG + I+ R
Sbjct: 790 PNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGR 849
Query: 198 VCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIY 233
CG+++P P + GSS+ + F+SD S GF A++
Sbjct: 850 FCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH 885
Score = 68.6 bits (166), Expect = 2e-11
Identities = 34/91 (37%), Positives = 49/91 (53%)
Query: 143 SYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNE 202
+YP A C+W I A+ G+ ++L F +E + C YDY+E DG + + R CG+
Sbjct: 912 NYPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGSG 971
Query: 203 RPAPIQSIGSSLHVLFHSDGSKNFDGFHAIY 233
I S G SL + F +D + N GFHA Y
Sbjct: 972 PLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 89.0 bits (219), Expect = 1e-17
Identities = 60/170 (35%), Positives = 81/170 (47%), Gaps = 15/170 (8%)
Query: 128 CGQVLRAPKGQILLESYPLNAH----CEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG ++ G I +YP + C W I GF + L F +E C YDY+E
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA-IYEEITACSSS 242
VRDG + +I R CG E+P I+S S L + F SDGS N GF ++E+ CS
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 243 PCFHDGTC---VLDKAGSYKCACLAGY----TGQRCENLLEAGKSKIKAS 285
+ G C L+ GSYKC+C GY +RCE +K+ S
Sbjct: 555 ---NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGS 601
Score = 80.5 bits (197), Expect = 5e-15
Identities = 47/116 (40%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 125 CMRCGQVLRAPKGQILLESYP----LNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
C CG+ L+ G YP + HC W I PG I L F L L +C YD
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEI 236
YVEVRDG R + R CG++ P PI S S L V F S + GF A+YE I
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 4/108 (3%)
Query: 128 CGQVLRAPKGQILL----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG L G I + YP N +C W + A + I L+F E + +C+YD+VE
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA 231
VR G D ++ + CG+E+P I S +++ V F SD + + GF A
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA 698
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 89.0 bits (219), Expect = 1e-17
Identities = 60/170 (35%), Positives = 81/170 (47%), Gaps = 15/170 (8%)
Query: 128 CGQVLRAPKGQILLESYPLNAH----CEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG ++ G I +YP + C W I GF + L F +E C YDY+E
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA-IYEEITACSSS 242
VRDG + +I R CG E+P I+S S L + F SDGS N GF ++E+ CS
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 243 PCFHDGTC---VLDKAGSYKCACLAGY----TGQRCENLLEAGKSKIKAS 285
+ G C L+ GSYKC+C GY +RCE +K+ S
Sbjct: 555 ---NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGS 601
Score = 80.5 bits (197), Expect = 5e-15
Identities = 47/116 (40%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 125 CMRCGQVLRAPKGQILLESYP----LNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
C CG+ L+ G YP + HC W I PG I L F L L +C YD
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEI 236
YVEVRDG R + R CG++ P PI S S L V F S + GF A+YE I
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 4/108 (3%)
Query: 128 CGQVLRAPKGQILL----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG L G I + YP N +C W + A + I L+F E + +C+YD+VE
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA 231
VR G D ++ + CG+E+P I S +++ V F SD + + GF A
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA 698
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 89.0 bits (219), Expect = 1e-17
Identities = 60/170 (35%), Positives = 81/170 (47%), Gaps = 15/170 (8%)
Query: 128 CGQVLRAPKGQILLESYPLNAH----CEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG ++ G I +YP + C W I GF + L F +E C YDY+E
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLE 494
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA-IYEEITACSSS 242
VRDG + +I R CG E+P I+S S L + F SDGS N GF ++E+ CS
Sbjct: 495 VRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRP 554
Query: 243 PCFHDGTC---VLDKAGSYKCACLAGY----TGQRCENLLEAGKSKIKAS 285
+ G C L+ GSYKC+C GY +RCE +K+ S
Sbjct: 555 ---NRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGS 601
Score = 80.5 bits (197), Expect = 5e-15
Identities = 47/116 (40%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 125 CMRCGQVLRAPKGQILLESYP----LNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
C CG+ L+ G YP + HC W I PG I L F L L +C YD
Sbjct: 319 CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYD 378
Query: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEI 236
YVEVRDG R + R CG++ P PI S S L V F S + GF A+YE I
Sbjct: 379 YVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAI 434
Score = 78.6 bits (192), Expect = 2e-14
Identities = 45/154 (29%), Positives = 72/154 (46%), Gaps = 10/154 (6%)
Query: 88 FENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWY----GGDCMR--CGQVLRAPKGQILL 141
F + C + G D G Y +CR+G+ DC C + + G I
Sbjct: 701 FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITS 760
Query: 142 ----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKR 197
+ YP C W I + PG ++L F+ + +E C YD++EV DG + ++ R
Sbjct: 761 PNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGR 820
Query: 198 VCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA 231
CG+++P P+ + GS + + F+SD S GF A
Sbjct: 821 FCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQA 854
Score = 76.3 bits (186), Expect = 1e-13
Identities = 47/144 (32%), Positives = 72/144 (50%), Gaps = 6/144 (4%)
Query: 128 CGQVLRAPKGQILL----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG L G I + YP N +C W + A + I L+F E + +C+YD+VE
Sbjct: 591 CGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVE 650
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA-IYEEITACSSS 242
VR G D ++ + CG+E+P I S +++ V F SD + + GF A + + CS
Sbjct: 651 VRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKD 710
Query: 243 PCFHDGTCVLDKAGSYKCACLAGY 266
CV + GSY+C C +G+
Sbjct: 711 NGGCQQDCV-NTFGSYECQCRSGF 733
Score = 70.5 bits (171), Expect = 5e-12
Identities = 41/125 (32%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 117 RAGWYGGDCMRCGQVLRAP--------KGQILLESYPLNAHCEWTIHAKPGFVIQLRFVM 168
R G+ CG +RA Q +YP CEW I A+ G+ ++L F
Sbjct: 849 RKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQT 908
Query: 169 LSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDG 228
+E + C YDY+E+ DG + + R CG+ P + S G S+ V FHSD + G
Sbjct: 909 FEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKG 968
Query: 229 FHAIY 233
FH Y
Sbjct: 969 FHLRY 973
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 87.4 bits (215), Expect = 4e-17
Identities = 68/257 (26%), Positives = 114/257 (44%), Gaps = 44/257 (17%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQ ++ +T F C G+L++E VV AAHC ++T+D+
Sbjct: 45 WPWQVSLQDKTG------------FHFCGGSLISEDWVVTAAHCG--------VRTSDV- 83
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
VV G+F D DE+ IQ L+I+ + +P + + ++ DI +LKL AR S V +CL
Sbjct: 84 VVAGEF--DQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCL 141
Query: 599 AASRDLSTSFQESHI-TVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIP 657
++ D F + GW + D L+ + ++ + C++
Sbjct: 142 PSADD---DFPAGTLCATTGWG--KTKYNANKTPDKLQQAALPLLSNAECKKSWGRR--- 193
Query: 658 VSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHR 717
+TD M CA + C ++GG P + W L+G+VSW +TCS
Sbjct: 194 --ITDVMICAG---ASGVSSCMGDSGG------PLVCQKDGAWTLVGIVSWG-SRTCSTT 241
Query: 718 LSTAFTKVLPFKDWIER 734
+ +V W+++
Sbjct: 242 TPAVYARVAKLIPWVQK 258
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 87.4 bits (215), Expect = 4e-17
Identities = 75/259 (28%), Positives = 116/259 (44%), Gaps = 41/259 (15%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQA++ R G H +C GAL+ +R V+ AAHC + +M T
Sbjct: 588 WPWQASLQVR--GRH-----------ICGGALIADRWVITAAHCFQE---DSMASTVLWT 631
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
V LGK +++ + S ++S ++LHP ++ D D+A+L+L S V+P+CL
Sbjct: 632 VFLGKVWQNSRWPGEV--SFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCL 689
Query: 599 AASRDLSTSFQES-HITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIP 657
A S F+ H + GW L R G ++ L+ V ++ LC E +
Sbjct: 690 PAR---SHFFEPGLHCWITGWGAL---REGGPISNALQKVDVQLIPQDLCSEVYR----- 738
Query: 658 VSVTDNMFCASWEPTAPSDICTAETGG-IAAVSFPGRASPEPRWHLMGLVSWSYDKTCSH 716
VT M CA + D C ++GG + + G RW L GLVSW C
Sbjct: 739 YQVTPRMLCAGYR-KGKKDACQGDSGGPLVCKALSG------RWFLAGLVSWGLG--CGR 789
Query: 717 -RLSTAFTKVLPFKDWIER 734
+T++ WI++
Sbjct: 790 PNYFGVYTRITGVISWIQQ 808
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 87.0 bits (214), Expect = 6e-17
Identities = 69/257 (26%), Positives = 114/257 (44%), Gaps = 44/257 (17%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQ ++ +T F C G+L++E VV AAHC ++T+D+
Sbjct: 45 WPWQVSLQDKTG------------FHFCGGSLISEDWVVTAAHCG--------VRTSDV- 83
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
VV G+F D DE+ IQ L+I+ + +P + + ++ DI +LKL AR S V +CL
Sbjct: 84 VVAGEF--DQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCL 141
Query: 599 AASRDLSTSFQESHI-TVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIP 657
++ D F + GW + D L+ + ++ + C++
Sbjct: 142 PSADD---DFPAGTLCATTGWG--KTKYNANKTPDKLQQAALPLLSNAECKKSWGRR--- 193
Query: 658 VSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHR 717
+TD M CA + C ++GG P + W L+G+VSW D TCS
Sbjct: 194 --ITDVMICAG---ASGVSSCMGDSGG------PLVCQKDGAWTLVGIVSWGSD-TCSTS 241
Query: 718 LSTAFTKVLPFKDWIER 734
+ +V W+++
Sbjct: 242 SPGVYARVTKLIPWVQK 258
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 84.7 bits (208), Expect = 3e-16
Identities = 50/144 (34%), Positives = 73/144 (50%), Gaps = 5/144 (3%)
Query: 128 CGQVLRAPKGQILLESYPLN----AHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG +R +GQI +YP + C W I + + L F +E C YDY+E
Sbjct: 462 CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLE 521
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHA-IYEEITACSSS 242
VRDG + + +I R CG ++P I+S ++L + F SDG+ N GF A ++E C+
Sbjct: 522 VRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKP 581
Query: 243 PCFHDGTCVLDKAGSYKCACLAGY 266
L+ GSY+CAC GY
Sbjct: 582 DRGGCEQRCLNTLGSYQCACEPGY 605
Score = 83.6 bits (205), Expect = 6e-16
Identities = 67/224 (29%), Positives = 96/224 (42%), Gaps = 21/224 (9%)
Query: 88 FENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWY----GGDCMR--CGQVLRAPKGQILL 141
F + C + G + G Y +CR G+ DC C Q + +P G I
Sbjct: 728 FSDKDECSKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITS 787
Query: 142 ----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKR 197
+ YP C W I A PG I+L F +E C YD++EV DG+ I+ R
Sbjct: 788 PNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGR 847
Query: 198 VCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGS 257
+CGN+ P P+ + G+ + V F SD S GF A + S+ C
Sbjct: 848 LCGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATH-------STECGGRLKAESKPRDL 900
Query: 258 YKCACLA--GYTGQ-RCENLLEAGK-SKIKASEDSLSVLEERNC 297
Y A Y GQ CE LL + + S+++ S + V EE +C
Sbjct: 901 YSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQTFEVEEEADC 944
Score = 76.6 bits (187), Expect = 7e-14
Identities = 40/116 (34%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Query: 125 CMRCGQVLRAPKGQI----LLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD 180
C CG+ L+ G + YP HC W + PG I L F + L +C YD
Sbjct: 346 CPACGETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYD 405
Query: 181 YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEI 236
Y+EVRDG R ++ R CG++ P + S S + + F S + GF A+YE I
Sbjct: 406 YIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI 461
Score = 75.5 bits (184), Expect = 2e-13
Identities = 52/169 (30%), Positives = 81/169 (47%), Gaps = 15/169 (8%)
Query: 110 GFYCAECRAGWYGGDCMR-----CGQVLRAPKGQILL----ESYPLNAHCEWTIHAKPGF 160
G Y C G+ G R CG +L G I + YP N +C W + A +
Sbjct: 595 GSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPKEYPPNKNCVWQVVAPTQY 654
Query: 161 VIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHS 220
I ++F LE + +C+YDYVE+ G + + ++ + CG E P I S +++ + F S
Sbjct: 655 RISVKFEFFELEGNEVCKYDYVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKS 714
Query: 221 DGSKNFDGFHA-IYEEITACS--SSPCFHDGTCVLDKAGSYKCACLAGY 266
D + + GF A + + CS + C H+ CV + GSY C C G+
Sbjct: 715 DNTVSKKGFKAHFFSDKDECSKDNGGCQHE--CV-NTMGSYMCQCRNGF 760
Score = 69.7 bits (169), Expect = 9e-12
Identities = 42/128 (32%), Positives = 61/128 (47%), Gaps = 8/128 (6%)
Query: 117 RAGWYGGDCMRCGQVLRAPK--------GQILLESYPLNAHCEWTIHAKPGFVIQLRFVM 168
R G+ CG L+A Q +YP CEW + ++ G ++L F
Sbjct: 876 RKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRLELSFQT 935
Query: 169 LSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDG 228
+E + C YDYVE+ DG + + R CG+ P I SIG S+ + FH+D + N G
Sbjct: 936 FEVEEEADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKG 995
Query: 229 FHAIYEEI 236
FH Y+ I
Sbjct: 996 FHIRYKSI 1003
>gi|7706083 complement component 1, r subcomponent-like precursor
[Homo sapiens]
Length = 487
Score = 84.0 bits (206), Expect = 5e-16
Identities = 78/324 (24%), Positives = 128/324 (39%), Gaps = 49/324 (15%)
Query: 426 QLQYECISPFYRRLGSSRRTCLRTGKWSGRAPS-----CIPICGKIENITAPKTQGL--- 477
++Q C P+Y+ + TC G W R C+P+CG+ A L
Sbjct: 190 KVQNHCQEPYYQAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSS 249
Query: 478 -----RWPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMI 532
+PWQA S+H GAL+ +R ++ AAH V V++
Sbjct: 250 RAKLGNFPWQAFT----------SIHGRG-----GGALLGDRWILTAAHTVYPKDSVSLR 294
Query: 533 KTADLKVVLGKFYRDDDRDEKTIQSLQISAIILHPNY---DPILLDADIAILKLLDKARI 589
K + V LG D + + + + +++HP+Y + DIA+L+L +
Sbjct: 295 KNQSVNVFLGHTAID---EMLKLGNHPVHRVVVHPDYRQNESHNFSGDIALLELQHSIPL 351
Query: 590 STRVQPICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEE 649
V P+CL + L S +++ G + G+ L+ + V C
Sbjct: 352 GPNVLPVCLPDNETLYRSGLLGYVSGFGMEM-------GWLTTELKYSRLPVAPREACNA 404
Query: 650 QHEDHGIPVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWS 709
+ P +DNMFC + T +C ++G + V + A W G+VSW
Sbjct: 405 WLQKRQRPEVFSDNMFCVG-DETQRHSVCQGDSGSVYVV-WDNHAH---HWVATGIVSWG 459
Query: 710 YDKTCSHRLSTAFTKVLPFKDWIE 733
C +TKVL + DWI+
Sbjct: 460 IG--CGEGYD-FYTKVLSYVDWIK 480
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 82.8 bits (203), Expect = 1e-15
Identities = 71/262 (27%), Positives = 112/262 (42%), Gaps = 44/262 (16%)
Query: 478 RWPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADL 537
RWPWQ SLH F +C G+LV+ER ++ AAHC+ T
Sbjct: 38 RWPWQV------------SLHFDHNF-ICGGSLVSERLILTAAHCIQPTW-----TTFSY 79
Query: 538 KVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPIC 597
V LG D R +S I++HP Y AD+A+LKL + ++ + PIC
Sbjct: 80 TVWLGSITVGDSRKR---VKYYVSKIVIHPKYQD--TTADVALLKLSSQVTFTSAILPIC 134
Query: 598 L-AASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGI 656
L + ++ L+ V GW + + + + L+ V ++D CE+ + GI
Sbjct: 135 LPSVTKQLAI---PPFCWVTGWGKVKESSDRDY-HSALQEAEVPIIDRQACEQLYNPIGI 190
Query: 657 ------PVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSY 710
PV + ++ CA + D C ++GG + G W G+VSW
Sbjct: 191 FLPALEPV-IKEDKICAG-DTQNMKDSCKGDSGGPLSCHIDG------VWIQTGVVSWGL 242
Query: 711 DKTCSHRLSTAFTKVLPFKDWI 732
+ C L +T V+ ++ WI
Sbjct: 243 E--CGKSLPGVYTNVIYYQKWI 262
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 81.6 bits (200), Expect = 2e-15
Identities = 63/243 (25%), Positives = 98/243 (40%), Gaps = 33/243 (13%)
Query: 127 RCGQVLRAPKGQILLE----SYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYV 182
+CG + +G IL +YP N C W I GF ++F+ S E ++ DY+
Sbjct: 1967 QCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNH----DYI 2022
Query: 183 EVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSS 242
E+R+G +++ R G+E P+ + S V FHSD S+N GF Y+++T
Sbjct: 2023 EIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQI 2082
Query: 243 PCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDPGG 302
F G + + +R + S + + E + C DP
Sbjct: 2083 SSFLRGFDLSEL--------------ERTNSTPPVAASYVWDLDPGCEAYELQECPDPEP 2128
Query: 303 PVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQ--NGEWSGKQPICI 360
N G++ G +G V+F C Y L+G+ TCQ N W P C
Sbjct: 2129 FAN---------GIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE 2179
Query: 361 KAC 363
C
Sbjct: 2180 VPC 2182
Score = 74.3 bits (181), Expect = 4e-13
Identities = 92/360 (25%), Positives = 144/360 (40%), Gaps = 35/360 (9%)
Query: 128 CGQVLRAPKGQILLESYPL----NAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG L +P G IL +P C W I A+PG+ I++ F E +Y D +E
Sbjct: 752 CGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNY----DTLE 807
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSP 243
VRDG +I G + P + S + L++LF +D S + GF YE IT S
Sbjct: 808 VRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETIT-LQSDH 866
Query: 244 CFHDGTCVLDK--------AGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVL--- 292
C G V + +C +GYT E L + + S L
Sbjct: 867 CLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGG 926
Query: 293 ----EERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQ 348
PG P + Y +I H G V F + ++ SG++ +
Sbjct: 927 FIQGSSGTILSPGFP-DFYPNNLNCTWIIETSH---GKGVFFTFHTFHLESGHDYLLITE 982
Query: 349 NGEWSGK-QPICIKACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTK 407
NG ++ + + P + L ++ S + ++ ++ FS+ L+ P +
Sbjct: 983 NGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLE--PCE 1040
Query: 408 KPALPFGDLPMGYQH-LHTQLQYECISPFYRRLGSSRRTCL--RTGKWSGRAPSCIPICG 464
+P +P + G Q + L + C P YR G++R TCL R WS P C+ CG
Sbjct: 1041 EPEVPAYSIRKGLQFGVGDTLTFSCF-PGYRLEGTARITCLGGRRRLWSSPLPRCVAECG 1099
Score = 73.2 bits (178), Expect = 8e-13
Identities = 67/243 (27%), Positives = 91/243 (37%), Gaps = 76/243 (31%)
Query: 128 CGQVLRAPKGQILLESYPL----NAHCEWTIHA-KPGFVIQLRFVMLSLEFDYMCQYDYV 182
C LR P G I ++P+ NAHC W I A P VI+L F EFD YD +
Sbjct: 405 CDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFE----EFDLERGYDTL 460
Query: 183 EVRDG--DNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACS 240
V DG D ++ + G P I S + +LF +DGS + GF A YEEI
Sbjct: 461 TVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEI---- 516
Query: 241 SSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDP 300
G+C DP
Sbjct: 517 -----EQGSC-----------------------------------------------GDP 524
Query: 301 GGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI 360
G P G ++ G G + F C ++ L G + TCQ+N +WS K+P C+
Sbjct: 525 GIPAYGRRE---------GSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCV 575
Query: 361 KAC 363
+C
Sbjct: 576 FSC 578
Score = 71.2 bits (173), Expect = 3e-12
Identities = 52/168 (30%), Positives = 66/168 (39%), Gaps = 52/168 (30%)
Query: 297 CSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQ 356
C+DPG P G Q N + ++G+ V F C Y+L G+ RTC N WSG
Sbjct: 3131 CADPGVPQFGIQN--------NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTP 3182
Query: 357 PICI-KACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGD 415
P C+ CR+P ETP H A D
Sbjct: 3183 PDCVPHHCRQP------------------ETPTHANVGAL-------------------D 3205
Query: 416 LP-MGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPI 462
LP MGY L Y C F + GS RTC G W+G+ P C+ +
Sbjct: 3206 LPSMGY-----TLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEV 3248
Score = 65.9 bits (159), Expect = 1e-10
Identities = 91/396 (22%), Positives = 144/396 (36%), Gaps = 56/396 (14%)
Query: 130 QVLRAPKGQILLESYPLN----AHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVR 185
++L G IL +SYP + C W + +P + I L E QYD E+
Sbjct: 2359 ELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK----QYDEFEIF 2414
Query: 186 DGDNRDGQIIKRVCGN-ERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPC 244
DG + ++K + GN P + S +S+++ + SD + N GF Y
Sbjct: 2415 DGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAP 2474
Query: 245 FHD---GTCVLDKAGSYKCACLAGY--TGQRCENLLEAGKSKIKASEDSLSVLEERNCSD 299
H G GS C AGY G + SE ++ + + +C
Sbjct: 2475 LHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSE-AIPLCQALSCGL 2533
Query: 300 PGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRT--CQQNGEWSGKQ- 356
P P N G++ G+ +GT + C+ Y L + T C G WS +
Sbjct: 2534 PEAPKN---------GMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNV 2584
Query: 357 -PICIK-ACREPKISDLV-----RRRVLPMQVQSRE------------TPLHQLYSAAFS 397
P C+ C P +S + R + Q Q + T + A
Sbjct: 2585 PPQCVPVTC--PDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANG 2642
Query: 398 KQKLQSAPTKKPALPFGDLPM--GYQHLHTQLQYECISPF-----YRRLGSSRRTCLRTG 450
K L + + G+LP+ + T Y + F Y +GS R C+ G
Sbjct: 2643 KWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANG 2702
Query: 451 KWSGRAPSCIP-ICGKIENITAPKTQGLRWPWQAAI 485
WSG C+ CG E I G + ++ ++
Sbjct: 2703 LWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSV 2738
Score = 62.8 bits (151), Expect = 1e-09
Identities = 67/242 (27%), Positives = 95/242 (39%), Gaps = 53/242 (21%)
Query: 128 CGQVLRAPKGQILLESYPL----NAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG LR G I +P NA C WTI A+ G I L F+ LE YD++E
Sbjct: 202 CGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG----YDFLE 257
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSP 243
V + G PAP+ S + L + F SDG+ GF A Y+
Sbjct: 258 VTGTEGSS----LWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQ--------- 304
Query: 244 CFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASE-DSLSVLEERN-CSDPG 301
+ K K R L+ + + K S + V + N C DPG
Sbjct: 305 --------VKKQIELK---------SRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPG 347
Query: 302 GPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGE----WSGKQP 357
P G + G ++G+ V F CN Y L G+++ TC + + WS +P
Sbjct: 348 IPERGKRL---------GSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRP 398
Query: 358 IC 359
+C
Sbjct: 399 VC 400
Score = 60.8 bits (146), Expect = 4e-09
Identities = 47/148 (31%), Positives = 65/148 (43%), Gaps = 13/148 (8%)
Query: 128 CGQVLRAPKGQILL----ESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG L P G IL E YP C+W + P +VI L F + +LE YD++
Sbjct: 1445 CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLE----PGYDFLH 1500
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEE--ITACSS 241
+ DG + +I G++ P I+S +SL + F SD S + GF Y E +C
Sbjct: 1501 IYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
Query: 242 SPCFHDGTCV---LDKAGSYKCACLAGY 266
+GT V L S C GY
Sbjct: 1561 PGSIKNGTRVGSDLKLGSSVTYYCHGGY 1588
Score = 58.2 bits (139), Expect = 3e-08
Identities = 48/170 (28%), Positives = 62/170 (36%), Gaps = 53/170 (31%)
Query: 297 CSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQ 356
C DPG P +G + G GTV+ F C +VL G+ +RTCQ NG WSG Q
Sbjct: 2835 CGDPGIPAHGIRL---------GDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQ 2885
Query: 357 PIC-IKACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGD 415
P C + +C P R FS + S
Sbjct: 2886 PECGVISCGNPGTPSNAR--------------------VVFSDGLVFS------------ 2913
Query: 416 LPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPI-CG 464
+ + YEC +Y G R C G W+G P C+ I CG
Sbjct: 2914 ---------SSIVYECREGYY-ATGLLSRHCSVNGTWTGSDPECLVINCG 2953
Score = 54.3 bits (129), Expect = 4e-07
Identities = 38/111 (34%), Positives = 53/111 (47%), Gaps = 8/111 (7%)
Query: 128 CGQVLRAPKGQI----LLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
C L P G + YP A+C WTI A+ IQL F +LE D+ D +
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDF----DVLS 81
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYE 234
V DG + + R+ G + PA I S ++L + SD + + GFHA YE
Sbjct: 82 VFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYE 132
Score = 52.4 bits (124), Expect = 2e-06
Identities = 49/218 (22%), Positives = 81/218 (37%), Gaps = 74/218 (33%)
Query: 134 APKGQILLESYPLN----AHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDN 189
+P G +L +YP + HC W I A+P I L F + +E Q+D++ ++DG
Sbjct: 584 SPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVE----PQFDFLVIKDGAT 639
Query: 190 RDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGT 249
+ ++ GN+ P+ I S G + F +D S
Sbjct: 640 AEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHS-------------------------- 673
Query: 250 CVLDKAGSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERNCSDPGGPVNGYQK 309
TG+R N+ + + C DPG PVNG +
Sbjct: 674 -----------------TGKRGFNI-------------TFTTFRHNECPDPGVPVNGKR- 702
Query: 310 ITGGPGLINGRHAKIGTVVSFFCNNSYV-LSGNEKRTC 346
G ++G+ +SF C+ ++ G+E TC
Sbjct: 703 --------FGDSLQLGSSISFLCDEGFLGTQGSETITC 732
Score = 51.2 bits (121), Expect = 3e-06
Identities = 50/190 (26%), Positives = 74/190 (38%), Gaps = 31/190 (16%)
Query: 296 NCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGK 355
+C P VNG+ ING + V + CN + L G R CQQ+ WSGK
Sbjct: 2715 HCGTPEPIVNGH---------INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGK 2765
Query: 356 QPICI-KACREP-------------KISDLVRRRVLPMQV----QSRETPLHQLYSAAFS 397
P C+ +C P + +VR + + +R L ++ +
Sbjct: 2766 TPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLP 2825
Query: 398 KQKLQSAPT-KKPALPFGDLPMGYQ-HLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGR 455
S P +P + +G T +++ C + R GSS RTC G WSG
Sbjct: 2826 HCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLR-GSSERTCQANGSWSGS 2884
Query: 456 APSC-IPICG 464
P C + CG
Sbjct: 2885 QPECGVISCG 2894
Score = 47.8 bits (112), Expect = 4e-05
Identities = 44/189 (23%), Positives = 74/189 (39%), Gaps = 29/189 (15%)
Query: 296 NCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGK 355
+C +PG P N ++ GL+ + + + C Y +G R C NG W+G
Sbjct: 2892 SCGNPGTPSNA--RVVFSDGLV------FSSSIVYECREGYYATGLLSRHCSVNGTWTGS 2943
Query: 356 QPICIKA-CREPKI--------SDLVRRRVLPMQ-VQSRETPLHQLYSAAFSKQKLQSA- 404
P C+ C +P I +D + + Q V H++ + +K + +
Sbjct: 2944 DPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGT 3003
Query: 405 -PTKK-------PALPFGDLPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRA 456
P K P +P G + + + Y C+ + L + TC G W+G
Sbjct: 3004 KPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSL-PAVFTCEGNGSWTGEL 3062
Query: 457 PSCIPI-CG 464
P C P+ CG
Sbjct: 3063 PQCFPVFCG 3071
Score = 47.4 bits (111), Expect = 5e-05
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)
Query: 128 CGQVLRAPKGQILLESYP---LNA-HCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG L +G IL +P LN+ +C W I G IQ++ V E ++ D +E
Sbjct: 1796 CGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNW----DSLE 1851
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSP 243
V DG + ++ G PA + S + L++ F+SD S + GFH Y+ + SS P
Sbjct: 1852 VFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTV-GLSSCP 1910
Score = 47.0 bits (110), Expect = 6e-05
Identities = 49/169 (28%), Positives = 67/169 (39%), Gaps = 24/169 (14%)
Query: 315 GLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKA-CREPKISDLVR 373
G + G G+ V++ C Y LS TC+ NG W+G+ P C C +P + R
Sbjct: 3021 GKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR 3080
Query: 374 RRVLPMQVQSRET-PLH-QLYSAAFSKQKLQSAPT----------------KKPALP-FG 414
R +S + H L ++ QS T P +P FG
Sbjct: 3081 REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFG 3140
Query: 415 --DLPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIP 461
+ GYQ T L + C Y GS+ RTCL WSG P C+P
Sbjct: 3141 IQNNSQGYQVGSTVL-FRC-QKGYLLQGSTTRTCLPNLTWSGTPPDCVP 3187
Score = 40.8 bits (94), Expect = 0.005
Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 16/159 (10%)
Query: 128 CGQVLRAPKGQILLESYPLNAH----CEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG + +G +L ++P+N + C ++I +PG IQL+ L + D ++
Sbjct: 1098 CGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELS-----EGDVLK 1152
Query: 184 VRDGDNRDGQIIKRVCGNE-RPAPIQSIGSSLHVLFHSDGSKNFDGF--HAIYEEITACS 240
V DG+N +++ +E + S SSL + F +D GF H E+ C
Sbjct: 1153 VYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCE 1212
Query: 241 SSPCFHDGTCVLDK----AGSYKCACLAGYTGQRCENLL 275
G V D+ S +C GY+ + E LL
Sbjct: 1213 DPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELL 1251
Score = 38.9 bits (89), Expect = 0.017
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 10/83 (12%)
Query: 283 KASEDSLSVLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNE 342
K E S E C DPG P GY+ ++ G+ VSF C+ Y L G+E
Sbjct: 1197 KGFELHFSSFELIKCEDPGTPKFGYK--------VHDEGHFAGSSVSFSCDPGYSLRGSE 1248
Query: 343 KRTC--QQNGEWSGKQPICIKAC 363
+ C + W P C+ C
Sbjct: 1249 ELLCLSGERRTWDRPLPTCVAEC 1271
Score = 37.0 bits (84), Expect = 0.066
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 17/116 (14%)
Query: 256 GSYKCACLAGYTGQRCENLLEAGKSKIKASEDSLSVLEERN----CSDPGGPVNGYQKIT 311
GS+ + L G +L A +S S + N C DPG NG +
Sbjct: 1513 GSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRV-- 1570
Query: 312 GGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGE----WSGKQPICIKAC 363
G K+G+ V+++C+ Y + G +C + W+ +P+C C
Sbjct: 1571 -------GSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPC 1619
Score = 35.8 bits (81), Expect = 0.15
Identities = 26/122 (21%), Positives = 52/122 (42%), Gaps = 10/122 (8%)
Query: 128 CGQVLRAPKGQILLESYPLNAH----CEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVE 183
CG G +L +YP N C + + +V+ +F F + D VE
Sbjct: 1619 CGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFA-----FFHTALNDVVE 1673
Query: 184 VRDGDNRDGQIIKRVCGNERPAPIQ-SIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSS 242
V DG ++ +++ + G+ + + + + + F + G GFH +Y+ + S++
Sbjct: 1674 VHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSAT 1733
Query: 243 PC 244
C
Sbjct: 1734 QC 1735
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 4/77 (5%)
Query: 397 SKQKLQSAPTKKPALP-FGDLPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGR 455
S ++++ P +P +G H L++EC P + +G TC + +WS +
Sbjct: 512 SYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFEC-QPAFELVGQKAITCQKNNQWSAK 570
Query: 456 APSCIPICGKIENITAP 472
P C+ C N T+P
Sbjct: 571 KPGCVFSC--FFNFTSP 585
Score = 35.0 bits (79), Expect = 0.25
Identities = 22/77 (28%), Positives = 32/77 (41%), Gaps = 12/77 (15%)
Query: 290 SVLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTC--- 346
SV +C+DPG P NG + +G + G F C+ Y L G+ + +C
Sbjct: 1378 SVSTATSCNDPGIPQNGSR---------SGDSWEAGDSTVFQCDPGYALQGSAEISCVKI 1428
Query: 347 QQNGEWSGKQPICIKAC 363
+ W P CI C
Sbjct: 1429 ENRFFWQPSPPTCIAPC 1445
Score = 34.3 bits (77), Expect = 0.43
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 9/74 (12%)
Query: 291 VLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNG 350
VL C +PG NG Q+ G +G V + CN + L G+ TC
Sbjct: 133 VLPSHTCGNPGRLPNGIQQ---------GSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGS 183
Query: 351 EWSGKQPICIKACR 364
E S + +CR
Sbjct: 184 ENSATWDFPLPSCR 197
Score = 32.3 bits (72), Expect = 1.6
Identities = 14/49 (28%), Positives = 22/49 (44%), Gaps = 4/49 (8%)
Query: 319 GRHAKIGTVVSFFCNNSYVLSGNEKRTC----QQNGEWSGKQPICIKAC 363
G +G +V F CN+ Y L G+ + C +W+ P C+ C
Sbjct: 1748 GSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPC 1796
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 81.3 bits (199), Expect = 3e-15
Identities = 69/259 (26%), Positives = 107/259 (41%), Gaps = 34/259 (13%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQ +++ G +C +L++ +V AAHC D
Sbjct: 626 WPWQVSLHALGQGH------------ICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWT 673
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
LG + R +Q ++ II HP ++ D DIA+L+L A S+ V+PICL
Sbjct: 674 AFLG-LHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICL 732
Query: 599 AASRDLSTSFQESH-ITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIP 657
D S F I V GW + G L+ G + V++ CE +P
Sbjct: 733 P---DASHVFPAGKAIWVTGW---GHTQYGGTGALILQKGEIRVINQTTCENL-----LP 781
Query: 658 VSVTDNMFCASWEPTAPSDICTAETGG-IAAVSFPGRASPEPRWHLMGLVSWSYDKTCSH 716
+T M C + + D C ++GG +++V GR G+VSW D
Sbjct: 782 QQITPRMMCVGF-LSGGVDSCQGDSGGPLSSVEADGRI------FQAGVVSWG-DGCAQR 833
Query: 717 RLSTAFTKVLPFKDWIERN 735
+T++ F+DWI+ N
Sbjct: 834 NKPGVYTRLPLFRDWIKEN 852
Score = 44.7 bits (104), Expect = 3e-04
Identities = 52/207 (25%), Positives = 75/207 (36%), Gaps = 54/207 (26%)
Query: 128 CGQVLRAPKGQILLE----SYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYM------- 176
CG LR +G YP N C W I +++RF +F Y+
Sbjct: 340 CGGRLRKAQGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRF-----KFFYLLEPGVPA 394
Query: 177 --CQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYE 234
C DYVE+ ++ CG + S + + V FHSD S GF A Y
Sbjct: 395 GTCPKDYVEING---------EKYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY- 444
Query: 235 EITACSSSPCFHDGTC-----------------VLDKAGSYKCACLAGY----TGQRCEN 273
++ SS PC TC D + C+C AG+ + C+
Sbjct: 445 -LSYDSSDPCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKFCKP 503
Query: 274 LLEAGKSKIKASEDSLSVLEERNCSDP 300
L S ++S +E+ CS P
Sbjct: 504 LFWVCDSVNDCGDNS----DEQGCSCP 526
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 80.9 bits (198), Expect = 4e-15
Identities = 80/268 (29%), Positives = 124/268 (46%), Gaps = 39/268 (14%)
Query: 480 PWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKV 539
PWQAAI+ + H S G FL C G L++ ++ AAHC + L V
Sbjct: 323 PWQAAIFAK----HRRS--PGERFL-CGGILISSCWILSAAHCFQE-----RFPPHHLTV 370
Query: 540 VLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDK----ARISTRVQP 595
+LG+ YR +E+ Q ++ I+H +D D DIA+L+L A+ S+ V+
Sbjct: 371 ILGRTYRVVPGEEE--QKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRT 428
Query: 596 ICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHG 655
+CL + + E ++ G + + SP F ++ L+ V + S C QH
Sbjct: 429 VCLPPADLQLPDWTECELSGYGKH---EALSP-FYSERLKEAHVRLYPSSRCTSQHL--- 481
Query: 656 IPVSVTDNMFCA----SWEPTAP-SDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSY 710
+ +VTDNM CA S P A D C ++GG GR + L+G++SW
Sbjct: 482 LNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMT------LVGIISWGL 535
Query: 711 DKTCSHR-LSTAFTKVLPFKDWIERNMK 737
C + + +TKV + DWI NM+
Sbjct: 536 G--CGQKDVPGVYTKVTNYLDWIRDNMR 561
Score = 30.8 bits (68), Expect = 4.7
Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 1/38 (2%)
Query: 236 ITACSSSPCFHDGTCVLDKAGS-YKCACLAGYTGQRCE 272
+ +CS CF+ GTC S + C C G+ G+ CE
Sbjct: 83 VKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCE 120
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 80.9 bits (198), Expect = 4e-15
Identities = 80/268 (29%), Positives = 124/268 (46%), Gaps = 39/268 (14%)
Query: 480 PWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKV 539
PWQAAI+ + H S G FL C G L++ ++ AAHC + L V
Sbjct: 277 PWQAAIFAK----HRRS--PGERFL-CGGILISSCWILSAAHCFQE-----RFPPHHLTV 324
Query: 540 VLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDK----ARISTRVQP 595
+LG+ YR +E+ Q ++ I+H +D D DIA+L+L A+ S+ V+
Sbjct: 325 ILGRTYRVVPGEEE--QKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRT 382
Query: 596 ICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHG 655
+CL + + E ++ G + + SP F ++ L+ V + S C QH
Sbjct: 383 VCLPPADLQLPDWTECELSGYGKH---EALSP-FYSERLKEAHVRLYPSSRCTSQHL--- 435
Query: 656 IPVSVTDNMFCA----SWEPTAP-SDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSY 710
+ +VTDNM CA S P A D C ++GG GR + L+G++SW
Sbjct: 436 LNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMT------LVGIISWGL 489
Query: 711 DKTCSHR-LSTAFTKVLPFKDWIERNMK 737
C + + +TKV + DWI NM+
Sbjct: 490 G--CGQKDVPGVYTKVTNYLDWIRDNMR 515
Score = 31.2 bits (69), Expect = 3.6
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 16/76 (21%)
Query: 198 VCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGS 257
+CG +P Q I H F G++++ G CS CF+ GTC S
Sbjct: 14 LCGAVFVSPSQEI----HARFRR-GARSYQG----------CSEPRCFNGGTCQQALYFS 58
Query: 258 -YKCACLAGYTGQRCE 272
+ C C G+ G+ CE
Sbjct: 59 DFVCQCPEGFAGKCCE 74
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 80.9 bits (198), Expect = 4e-15
Identities = 68/261 (26%), Positives = 114/261 (43%), Gaps = 40/261 (15%)
Query: 478 RWPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADL 537
RWPWQ ++ SG +C L+ ++ V+ AHC +
Sbjct: 812 RWPWQCSLQSEPSGH------------ICGCVLIAKKWVLTVAHCFEGRENAAV-----W 854
Query: 538 KVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPIC 597
KVVLG + D +Q+ + IILHP Y ++D DI+I++L + + V+P+C
Sbjct: 855 KVVLG--INNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVC 912
Query: 598 LAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIP 657
L +++ + GW + + + P FK L+ G V ++ C+ +
Sbjct: 913 LPNPEQWLE--PDTYCYITGWGHMGN-KMP-FK---LQEGEVRIISLEHCQSYFD----M 961
Query: 658 VSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHR 717
++T M CA +E + D C ++GG PG RW L GL SW C +
Sbjct: 962 KTITTRMICAGYE-SGTVDSCMGDSGGPLVCEKPG-----GRWTLFGLTSWG--SVCFSK 1013
Query: 718 L--STAFTKVLPFKDWIERNM 736
+ ++ V F +WI+R +
Sbjct: 1014 VLGPGVYSNVSYFVEWIKRQI 1034
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 80.9 bits (198), Expect = 4e-15
Identities = 68/257 (26%), Positives = 114/257 (44%), Gaps = 45/257 (17%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQA++ + G H C +L++ R ++ AAHC + T +
Sbjct: 196 WPWQASM--QWKGRH-----------YCGASLISSRWLLSAAHCFAKKNN-SKDWTVNFG 241
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
+V+ K Y + ++ II H NY L DIA+++L ++ + ++ ICL
Sbjct: 242 IVVNKPY----------MTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICL 291
Query: 599 -AASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIP 657
A LS + ++ V GW L G L+ + ++D+ +C + G
Sbjct: 292 PEAKMKLS---ENDNVVVTGWGTL---YMNGSFPVILQEDFLKIIDNKICNASYAYSGF- 344
Query: 658 VSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPR--WHLMGLVSWSYDKTCS 715
VTD M CA + + +D C ++GG A P+ R WHL+G+VSW D
Sbjct: 345 --VTDTMLCAGF-MSGEADACQNDSGGPLAY-------PDSRNIWHLVGIVSWG-DGCGK 393
Query: 716 HRLSTAFTKVLPFKDWI 732
+T+V +++WI
Sbjct: 394 KNKPGVYTRVTSYRNWI 410
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 80.5 bits (197), Expect = 5e-15
Identities = 66/255 (25%), Positives = 110/255 (43%), Gaps = 36/255 (14%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQ ++ + + +C G+L+ + V+ AAHC L D+
Sbjct: 402 WPWQVSLQVKLTAQRH----------LCGGSLIGHQWVLTAAHCFDGL------PLQDVW 445
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
+ D + T S QI II+H NY + DIA++KL + +PICL
Sbjct: 446 RIYSGILNLSDITKDTPFS-QIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504
Query: 599 AASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPV 658
+ D ST + +T GW + G + L+ + +V + C+++++D+
Sbjct: 505 PSKGDTSTIYTNCWVT--GWGF---SKEKGEIQNILQKVNIPLVTNEECQKRYQDY---- 555
Query: 659 SVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHRL 718
+T M CA ++ D C ++GG G W L+G+ SW + C+ R
Sbjct: 556 KITQRMVCAGYK-EGGKDACKGDSGGPLVCKHNG------MWRLVGITSWG--EGCARRE 606
Query: 719 ST-AFTKVLPFKDWI 732
+TKV + DWI
Sbjct: 607 QPGVYTKVAEYMDWI 621
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 80.1 bits (196), Expect = 7e-15
Identities = 60/255 (23%), Positives = 110/255 (43%), Gaps = 36/255 (14%)
Query: 479 WPWQAAIYRRTSGVHDGSLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLK 538
WPWQ ++ + +C G+++ + ++ AAHC + + L+
Sbjct: 399 WPWQVTLHTTSPTQRH----------LCGGSIIGNQWILTAAHCFYGVESPKI-----LR 443
Query: 539 VVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICL 598
V G + + +++ + +Q II+H Y DIA+LKL + +PICL
Sbjct: 444 VYSGILNQSEIKEDTSFFGVQ--EIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL 501
Query: 599 AASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPV 658
+ D + + + +T G+ L D +TL+ + +V + C++++ H
Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDK-----IQNTLQKAKIPLVTNEECQKRYRGH---- 552
Query: 659 SVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDKTCSHR- 717
+T M CA + D C ++GG P WHL+G+ SW + C+ R
Sbjct: 553 KITHKMICAGYR-EGGKDACKGDSGG------PLSCKHNEVWHLVGITSWG--EGCAQRE 603
Query: 718 LSTAFTKVLPFKDWI 732
+T V+ + DWI
Sbjct: 604 RPGVYTNVVEYVDWI 618
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,185,867
Number of Sequences: 37866
Number of extensions: 1622062
Number of successful extensions: 6131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 205
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 3521
Number of HSP's gapped (non-prelim): 2153
length of query: 737
length of database: 18,247,518
effective HSP length: 110
effective length of query: 627
effective length of database: 14,082,258
effective search space: 8829575766
effective search space used: 8829575766
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.