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Search of human proteins with 49170034
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|49170034 integrin, alpha 8 [Homo sapiens]
(1063 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|49170034 integrin, alpha 8 [Homo sapiens] 2158 0.0
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 970 0.0
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 923 0.0
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 922 0.0
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 899 0.0
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 709 0.0
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 369 e-102
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 366 e-101
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 344 2e-94
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 343 5e-94
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 312 1e-84
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 304 3e-82
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 300 5e-81
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 289 8e-78
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 285 2e-76
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 223 6e-58
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 192 1e-48
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 173 9e-43
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 167 6e-41
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 153 9e-37
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 152 2e-36
gi|62548866 integrin, alpha D precursor [Homo sapiens] 149 1e-35
gi|148728188 integrin, alpha E precursor [Homo sapiens] 142 2e-33
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 141 3e-33
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 141 4e-33
gi|34452173 integrin alpha X precursor [Homo sapiens] 138 3e-32
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 48 6e-05
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 42 0.003
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ... 33 1.9
gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens] 31 7.1
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 2158 bits (5591), Expect = 0.0
Identities = 1063/1063 (100%), Positives = 1063/1063 (100%)
Query: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA 60
MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA
Sbjct: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA 60
Query: 61 VDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIR 120
VDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIR
Sbjct: 61 VDFHIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIR 120
Query: 121 VNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSA 180
VNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSA
Sbjct: 121 VNGTKEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSA 180
Query: 181 YAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANY 240
YAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANY
Sbjct: 181 YAEFSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANY 240
Query: 241 SFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSI 300
SFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSI
Sbjct: 241 SFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSI 300
Query: 301 INSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQI 360
INSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQI
Sbjct: 301 INSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQI 360
Query: 361 YLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVL 420
YLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVL
Sbjct: 361 YLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVL 420
Query: 421 IYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAV 480
IYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAV
Sbjct: 421 IYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAV 480
Query: 481 YRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMA 540
YRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMA
Sbjct: 481 YRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMA 540
Query: 541 EVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPI 600
EVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPI
Sbjct: 541 EVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPI 600
Query: 601 NISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKH 660
NISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKH
Sbjct: 601 NISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKH 660
Query: 661 QVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENV 720
QVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENV
Sbjct: 661 QVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENV 720
Query: 721 TRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQIN 780
TRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQIN
Sbjct: 721 TRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQIN 780
Query: 781 ITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTIL 840
ITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTIL
Sbjct: 781 ITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTIL 840
Query: 841 EVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIP 900
EVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIP
Sbjct: 841 EVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIP 900
Query: 901 HLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQ 960
HLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQ
Sbjct: 901 HLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQ 960
Query: 961 RKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAIL 1020
RKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAIL
Sbjct: 961 RKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAIL 1020
Query: 1021 LGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA 1063
LGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA
Sbjct: 1021 LGLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA 1063
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 970 bits (2507), Expect = 0.0
Identities = 500/1052 (47%), Positives = 691/1052 (65%), Gaps = 31/1052 (2%)
Query: 8 GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67
GPRG PL+ G+LL P C+AFNLDV+ YSGP+GSYFG+AVDF +P
Sbjct: 12 GPRG--LPLLLS--------GLLL--PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPS 59
Query: 68 ARTAS-VLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKE 126
A + +LVGAPKANT+QP IVEGG V C W + + +C+ I FD T NR + +
Sbjct: 60 ASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSS--TRRCQPIEFDATGNRDYAKD---D 114
Query: 127 PIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSP 186
P+EFKS+QWFGA+V++ + K++ACAPLYHWRT + E++PVGTC+ +Q+ + E++P
Sbjct: 115 PLEFKSHQWFGASVRSKQDKILACAPLYHWRT-EMKQEREPVGTCF--LQDGTKTVEYAP 171
Query: 187 CRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDIL 246
CR+ + D +GQG+CQ GFS+DF K +++GGPGSFYWQGQ+I+ VA+I++ Y
Sbjct: 172 CRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYS 231
Query: 247 RKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDM 306
K + T A A +DDSYLGYSVA G+F GD + V+G+PR A+ G V I + +M
Sbjct: 232 IKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNM 291
Query: 307 TFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQV 366
+ + NFTGEQMA+YFG++V +D+N D DV +GAPLFM+R + +EVGQ+ + LQ
Sbjct: 292 SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 351
Query: 367 SSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK 426
+S F+ + L G E F RFGSA+A LGDL+QDG+NDIAI P+ G+D++G V I+NG
Sbjct: 352 ASGDFQTTK-LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 410
Query: 427 DGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPV 486
GLN PSQ+L+G WA+ ++P FG++++G +DIDKN YPDLIVGAFG + +YRARPV
Sbjct: 411 TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 470
Query: 487 VTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA-NTIVLMAEVQLD 545
+TV+A L ++P I+N +NKTC +P + +CF++R C G+ + + E+ LD
Sbjct: 471 ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 530
Query: 546 SLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLN 605
LKQKGAI+R LFL + + I R QC++ I YLRDE+EFRDKL+PI I +
Sbjct: 531 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 590
Query: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIG 665
Y LD T + ++PILN + +S QAHIL+DCGEDN+C P L++S D+ ++ IG
Sbjct: 591 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 650
Query: 666 DENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVV 725
D+N L LI+ A+N+GEGAYEAEL V IP +AD++G+ RNN+ LSC +K EN TR VV
Sbjct: 651 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVV 710
Query: 726 CDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVA 785
CDLGNPM +GT GLRF+V + + + S+ FDLQI+SSN + S VS ++++ +A
Sbjct: 711 CDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 770
Query: 786 QVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWP 845
VEIRGVS P I LPI NWE +E P EE+VGP+V+HIYEL N GPS+ S +L + WP
Sbjct: 771 AVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWP 830
Query: 846 FSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRK 905
+ + LLYI H GP+ C + INP IK +S + T + HL+ K
Sbjct: 831 YKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIK-ISSLQTTEKNDTVAGQGERDHLITK 889
Query: 906 RDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKND- 964
RD+ + E L C +CL+I C VGRL+ G+SA+L V+S LW TF+ ++N
Sbjct: 890 RDLALSE----GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 945
Query: 965 -PYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGL 1023
Y+L S SF V + PY + P + S + T+V W +P+WVIILA+L GL
Sbjct: 946 HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 1005
Query: 1024 LVLAILTLALWKCGFFDRARPPQEDMTDREQL 1055
L+LA+L +++ GFF R RPPQE+ +REQL
Sbjct: 1006 LLLAVLVFVMYRMGFFKRVRPPQEEQ-EREQL 1036
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 923 bits (2385), Expect = 0.0
Identities = 482/1062 (45%), Positives = 678/1062 (63%), Gaps = 36/1062 (3%)
Query: 8 GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67
GPR + P + PL L +L P FNLD E V SGP GS+FG++V+F+ P
Sbjct: 18 GPR--RRPPLLPLL-----LLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPG 70
Query: 68 ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGT--- 124
SVLVGAPKANTSQP +++GGAVY CPW A + QC I FD+ +R + + +
Sbjct: 71 TDGVSVLVGAPKANTSQPGVLQGGAVYLCPWGASPT-QCTPIEFDSKGSRLLESSLSSSE 129
Query: 125 -KEPIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAE 183
+EP+E+KS QWFGATV+AH ++ACAPLY WRT K P DPVGTCY++ NF+ E
Sbjct: 130 GEEPVEYKSLQWFGATVRAHGSSILACAPLYSWRTEKE-PLSDPVGTCYLSTDNFTRILE 188
Query: 184 FSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFK 243
++PCR+ + GQGYCQ GFS +F K G +++GGPGS++WQGQ+++A+ I +Y +
Sbjct: 189 YAPCRSDFSWAAGQGYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPE 248
Query: 244 DILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINS 303
++ + G+ QT A + YDDSYLGYSVA GEF+GD ++ VAG+P+G +GYV+I+N
Sbjct: 249 YLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNG 308
Query: 304 TDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLY 363
+D+ + NF+GEQMASYFGY V +DVN DGLDD+LVGAPL M+R + P+EVG++Y+Y
Sbjct: 309 SDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVY 368
Query: 364 LQVSSLLFRDPQI-LTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIY 422
LQ + + P + LTG + FGRFGS++ LGDL+QDGYND+AIG PF G+ Q+G V ++
Sbjct: 369 LQHPAGIEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVF 428
Query: 423 NGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYR 482
G GL +KPSQVLQ +WA+ P FG LRG D+D N YPDLIVG+FG K VYR
Sbjct: 429 PGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYR 488
Query: 483 ARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEV 542
RP+V+ A L + P + N E ++C + + AC +L C + +G+ +A++I E+
Sbjct: 489 GRPIVSASASLTIFPAMFNPEERSCSLEGN--PVACINLSFCLNASGKHVADSIGFTVEL 546
Query: 543 QLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINI 602
QLD KQKG ++R LFL + QA L+I+ C++ +YLR+E+EFRDKLSPI+I
Sbjct: 547 QLDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHI 606
Query: 603 SLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQV 662
+LN+SLD + ++P L+Y ++ + ++A IL+DCGEDN+CVPDL+L +++ V
Sbjct: 607 ALNFSLDPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEVFGEQNHV 666
Query: 663 IIGDENHLMLIINARNEGE-GAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVT 721
+GD+N L L +A+N GE GAYEAEL V P EA+Y G+ R+ F LSC+Y N +
Sbjct: 667 YLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQS 726
Query: 722 RMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINI 781
R++VCDLGNPM +G + GLRF VP L T +I FD QI S N +N S+ VS ++++
Sbjct: 727 RLLVCDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSV 786
Query: 782 TAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILE 841
A AQV + GVS P ++ P+ +W P ++P KEE++GP V H+YEL N GPS+IS +LE
Sbjct: 787 EAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELINQGPSSISQGVLE 846
Query: 842 VGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPH 901
+ P + + LLY+ + L C N INP+ + E PE S H
Sbjct: 847 LSCPQALEGQQLLYVTRVT---GLNCTTNHPINPKGL------ELDPEGSL--------H 889
Query: 902 LVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQR 961
+KR+ P +IL C EC ++ C +G L ES L++ R+WA TFLQR
Sbjct: 890 HQQKREAPSRSSASSGP-QILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQR 948
Query: 962 KNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILL 1021
++ P++L ++ KMPY P +LP+ + T+V W S+ +PLW+IILAIL
Sbjct: 949 EHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILF 1008
Query: 1022 GLLVLAILTLALWKCGFFDRARPPQEDMTDREQLTNDKTPEA 1063
GLL+L +L L+K GFF R+ P M ++ QL T +A
Sbjct: 1009 GLLLLGLLIYILYKLGFFKRSLPYGTAM-EKAQLKPPATSDA 1049
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 922 bits (2383), Expect = 0.0
Identities = 468/986 (47%), Positives = 651/986 (66%), Gaps = 18/986 (1%)
Query: 73 VLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKS 132
+LVGAPKANT+QP IVEGG V C W + + +C+ I FD T NR + +P+EFKS
Sbjct: 20 LLVGAPKANTTQPGIVEGGQVLKCDWSS--TRRCQPIEFDATGNRDYAKD---DPLEFKS 74
Query: 133 NQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSPCRNSNA 192
+QWFGA+V++ + K++ACAPLYHWRT + E++PVGTC+ +Q+ + E++PCR+ +
Sbjct: 75 HQWFGASVRSKQDKILACAPLYHWRT-EMKQEREPVGTCF--LQDGTKTVEYAPCRSQDI 131
Query: 193 DPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGE 252
D +GQG+CQ GFS+DF K +++GGPGSFYWQGQ+I+ VA+I++ Y K +
Sbjct: 132 DADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ 191
Query: 253 KQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQNF 312
T A A +DDSYLGYSVA G+F GD + V+G+PR A+ G V I + +M+ + NF
Sbjct: 192 LATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNF 251
Query: 313 TGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSSLLFR 372
TGEQMA+YFG++V +D+N D DV +GAPLFM+R + +EVGQ+ + LQ +S F+
Sbjct: 252 TGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQ 311
Query: 373 DPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTK 432
+ L G E F RFGSA+A LGDL+QDG+NDIAI P+ G+D++G V I+NG GLN
Sbjct: 312 TTK-LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAV 370
Query: 433 PSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQ 492
PSQ+L+G WA+ ++P FG++++G +DIDKN YPDLIVGAFG + +YRARPV+TV+A
Sbjct: 371 PSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAG 430
Query: 493 LLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA-NTIVLMAEVQLDSLKQKG 551
L ++P I+N +NKTC +P + +CF++R C G+ + + E+ LD LKQKG
Sbjct: 431 LEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKG 490
Query: 552 AIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDES 611
AI+R LFL + + I R QC++ I YLRDE+EFRDKL+PI I + Y LD
Sbjct: 491 AIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYR 550
Query: 612 TFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIGDENHLM 671
T + ++PILN + +S QAHIL+DCGEDN+C P L++S D+ ++ IGD+N L
Sbjct: 551 TAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLT 610
Query: 672 LIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNP 731
LI+ A+N+GEGAYEAEL V IP +AD++G+ RNN+ LSC +K EN TR VVCDLGNP
Sbjct: 611 LIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP 670
Query: 732 MVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRG 791
M +GT GLRF+V + + + S+ FDLQI+SSN + S VS ++++ +A VEIRG
Sbjct: 671 MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRG 730
Query: 792 VSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDE 851
VS P I LPI NWE +E P EE+VGP+V+HIYEL N GPS+ S +L + WP+ +
Sbjct: 731 VSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN 790
Query: 852 FLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVV 911
LLYI H GP+ C + INP IK +S + T + HL+ KRD+ +
Sbjct: 791 TLLYILHYDIDGPMNCTSDMEINPLRIK-ISSLQTTEKNDTVAGQGERDHLITKRDLALS 849
Query: 912 EFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKND--PYALA 969
E L C +CL+I C VGRL+ G+SA+L V+S LW TF+ ++N Y+L
Sbjct: 850 E----GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLK 905
Query: 970 SLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAIL 1029
S SF V + PY + P + S + T+V W +P+WVIILA+L GLL+LA+L
Sbjct: 906 SSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVL 965
Query: 1030 TLALWKCGFFDRARPPQEDMTDREQL 1055
+++ GFF R RPPQE+ +REQL
Sbjct: 966 VFVMYRMGFFKRVRPPQEEQ-EREQL 990
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 899 bits (2322), Expect = 0.0
Identities = 478/1052 (45%), Positives = 662/1052 (62%), Gaps = 67/1052 (6%)
Query: 8 GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67
GPRG PL+ G+LL P C+AFNLDV+ YSGP+GSYFG+AVDF +P
Sbjct: 12 GPRG--LPLLLS--------GLLL--PLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPS 59
Query: 68 ARTAS-VLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKE 126
A + +LVGAPKANT+QP IVEGG V C W + + +C+ I FD T NR + +
Sbjct: 60 ASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSS--TRRCQPIEFDATGNRDYAKD---D 114
Query: 127 PIEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFSP 186
P+EFKS+QWFGA+V++ + K++ACAPLYHWRT + E++PVGTC+ +Q+ + E++P
Sbjct: 115 PLEFKSHQWFGASVRSKQDKILACAPLYHWRT-EMKQEREPVGTCF--LQDGTKTVEYAP 171
Query: 187 CRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDIL 246
CR+ Q+I+ VA+I++ Y
Sbjct: 172 CRSR------------------------------------QLISDQVAEIVSKYDPNVYS 195
Query: 247 RKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDM 306
K + T A A +DDSYLGYSVA G+F GD + V+G+PR A+ G V I + +M
Sbjct: 196 IKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNM 255
Query: 307 TFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQV 366
+ + NFTGEQMA+YFG++V +D+N D DV +GAPLFM+R + +EVGQ+ + LQ
Sbjct: 256 SSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQR 315
Query: 367 SSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK 426
+S F+ + L G E F RFGSA+A LGDL+QDG+NDIAI P+ G+D++G V I+NG
Sbjct: 316 ASGDFQTTK-LNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRS 374
Query: 427 DGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPV 486
GLN PSQ+L+G WA+ ++P FG++++G +DIDKN YPDLIVGAFG + +YRARPV
Sbjct: 375 TGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPV 434
Query: 487 VTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA-NTIVLMAEVQLD 545
+TV+A L ++P I+N +NKTC +P + +CF++R C G+ + + E+ LD
Sbjct: 435 ITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD 494
Query: 546 SLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLN 605
LKQKGAI+R LFL + + I R QC++ I YLRDE+EFRDKL+PI I +
Sbjct: 495 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFME 554
Query: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVIIG 665
Y LD T + ++PILN + +S QAHIL+DCGEDN+C P L++S D+ ++ IG
Sbjct: 555 YRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIG 614
Query: 666 DENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVV 725
D+N L LI+ A+N+GEGAYEAEL V IP +AD++G+ RNN+ LSC +K EN TR VV
Sbjct: 615 DDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVV 674
Query: 726 CDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVA 785
CDLGNPM +GT GLRF+V + + + S+ FDLQI+SSN + S VS ++++ +A
Sbjct: 675 CDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 734
Query: 786 QVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWP 845
VEIRGVS P I LPI NWE +E P EE+VGP+V+HIYEL N GPS+ S +L + WP
Sbjct: 735 AVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWP 794
Query: 846 FSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRK 905
+ + LLYI H GP+ C + INP IK +S + T + HL+ K
Sbjct: 795 YKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIK-ISSLQTTEKNDTVAGQGERDHLITK 853
Query: 906 RDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKND- 964
RD+ + E L C +CL+I C VGRL+ G+SA+L V+S LW TF+ ++N
Sbjct: 854 RDLALSE----GDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQN 909
Query: 965 -PYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGL 1023
Y+L S SF V + PY + P + S + T+V W +P+WVIILA+L GL
Sbjct: 910 HSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGL 969
Query: 1024 LVLAILTLALWKCGFFDRARPPQEDMTDREQL 1055
L+LA+L +++ GFF R RPPQE+ +REQL
Sbjct: 970 LLLAVLVFVMYRMGFFKRVRPPQEEQ-EREQL 1000
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 709 bits (1830), Expect = 0.0
Identities = 421/1061 (39%), Positives = 599/1061 (56%), Gaps = 57/1061 (5%)
Query: 17 IAPLCCAAAALGMLLW---------SPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67
+A C AL +L W +P A NLD +LT Y+GP GS FG+++DFH
Sbjct: 1 MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDS 60
Query: 68 ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEP 127
+++VGAP+ T P E G V+ CPW AEG QC + FD + + R G++
Sbjct: 61 HGRVAIVVGAPR--TLGPSQEETGGVFLCPWRAEGG-QCPSLLFDLRD--ETRNVGSQTL 115
Query: 128 IEFKSNQWFGATVKAHKGKVVACAPLYHWRTLKPTPE--KDPVGTCYVAIQNFSAYAEFS 185
FK+ Q GA+V + +VACAP HW L+ T E K PVG+C++A AE+S
Sbjct: 116 QTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYS 175
Query: 186 PCRNS--------NADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADII 237
PCR + N + YC+AGFS + G+L++G PG +Y+ G + A VADI
Sbjct: 176 PCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIF 235
Query: 238 ANYSFKDILRKLAGEKQT-EVAPASYDDSYLGYSVAAGEFTGD-SQQELVAGIPRGAQNF 295
++Y +L ++ + + + + Y D Y GYSVA GEF GD + E V G P +
Sbjct: 236 SSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTL 295
Query: 296 GYVSIINSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPR 355
G V I++S + GEQMASYFG++V V+DVN DG D+LVGAPL+ME +
Sbjct: 296 GAVEILDSYYQR-LHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLA 354
Query: 356 EVGQIYLYLQVSS--LLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGK 413
EVG++YL+LQ L +LTGT+ +GRFGSA+A LGDL++DGYNDIA+ P+ G
Sbjct: 355 EVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGP 414
Query: 414 DQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAF 473
RG+VL++ G +GL ++PSQVL + + S FGF+LRG DID N YPDLIVGA+
Sbjct: 415 SGRGQVLVFLGQSEGLRSRPSQVLDSPFPTG---SAFGFSLRGAVDIDDNGYPDLIVGAY 471
Query: 474 GTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIA 533
G +VAVYRA+PVV QLL+ + N K+C +P + T +CF++++C TG +I
Sbjct: 472 GANQVAVYRAQPVVKASVQLLVQDSL-NPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIP 530
Query: 534 NTIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEF 593
+ L AE+QLD K + +R L L + QA L + + S C + +LRDE +F
Sbjct: 531 QKLSLNAELQLDRQKPRQG-RRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADF 589
Query: 594 RDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKL 653
RDKLSPI +SLN SL + + P + + + V EQ I++DCGED++CVP L+L
Sbjct: 590 RDKLSPIVLSLNVSLPPTE----AGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQL 645
Query: 654 SARPDKHQVIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSC 713
+A +++G +N L L ++A NEGEGAYEAEL V +P+ A Y+ N +GF L C
Sbjct: 646 TASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLIC 705
Query: 714 EYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN 773
K EN TR+V+C+LGNPM + + +V LE+ S++F LQIRS N NP+S
Sbjct: 706 NQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSK 765
Query: 774 FVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPS 833
V L + + A AQVE+RG S P +V+ E E E + + GP VEH YELHN GP
Sbjct: 766 IVLLDVPVRAEAQVELRGNSFPASLVVAAE--EGEREQNSLDSWGPKVEHTYELHNNGPG 823
Query: 834 TISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIK---PAASPEDTPEL 890
T++ L + P ++ LLYI IQ G LQC P P +NP + P SP
Sbjct: 824 TVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPI--- 880
Query: 891 SAFLRNSTIPHLVRKRDVHVVEFHRQSPAK---ILNCTNIECLQISCAVGRLEGGESAVL 947
H +R + + E + S + +++C + C + C + + G+ A++
Sbjct: 881 ------HPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMV 934
Query: 948 KVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVS 1007
V + LW + QR D + L S F V +PY P LP G + T ++ A
Sbjct: 935 TVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALE--E 992
Query: 1008 FSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQED 1048
+IP+W +++ +L GLL+L IL LA+WK GFF R RPP E+
Sbjct: 993 RAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEE 1033
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 369 bits (948), Expect = e-102
Identities = 315/1119 (28%), Positives = 519/1119 (46%), Gaps = 133/1119 (11%)
Query: 20 LCCAAAALGMLLWSPACQAFNLDVEKLTVYS--GPKGSYFGYAVDFH--IPDARTASVLV 75
LC + G+L S AFNLD + V G GS FG+++ H + +LV
Sbjct: 7 LCLLYLSAGLL--SRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLV 64
Query: 76 GAPKANTSQPDIVEG-GAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQ 134
GAP+A G +Y C A G C +I FD N E K +Q
Sbjct: 65 GAPRAEALPLQRANRTGGLYSCDITARGP--CTRIEFD---------NDADPTSESKEDQ 113
Query: 135 WFGATVKAHK--GKVVACAPLYHWRTLKPTPE--KDPVGTCYVAIQNFSAY-----AEFS 185
W G TV++ GKVV CA Y R T + +D G CYV QN ++S
Sbjct: 114 WMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWS 173
Query: 186 PCRNSNADPEGQGYCQAGFSLDFYKNGDLIV-GGPGSFYWQGQVITASVADIIANYS-FK 243
C E G CQ G + F K+ IV G PG++ W+G V + + + F+
Sbjct: 174 FCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFE 233
Query: 244 DILRKLAGEKQTEVAPASYD-DSYLGYSVAAGE-FTGDSQQELVAGIPRGAQNFGYVSI- 300
D ++ GE + + + +SYLG+S+ +G+ + V+G PR + V +
Sbjct: 234 DGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLK 293
Query: 301 --INSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVG 358
+ S + F GE +AS FGY V V D+N DG D+++GAP + +R+ E G
Sbjct: 294 RDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVG----G 349
Query: 359 QIYLYLQVSSLLFR-DPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRG 417
+Y+Y+ P L GT+ FG A+ ++GD+NQDGY DIA+G P+ D G
Sbjct: 350 AVYVYMNQQGRWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLG 405
Query: 418 KVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGK 477
KV IY+G+ +G+NTKP+QVL+G+ FG+++ G+ D+D+N YPD+ VG+ +
Sbjct: 406 KVFIYHGSANGINTKPTQVLKGI------SPYFGYSIAGNMDLDRNSYPDVAVGSL-SDS 458
Query: 478 VAVYRARPVVTVDAQLLLHPMIINLENKT-CQVPDSMTSAACFSLRVCASVTGQSIAN-- 534
V ++R+RPV+ + + + P I+L KT C P S C ++ C T
Sbjct: 459 VTIFRSRPVINIQKTITVTPNRIDLRQKTACGAP----SGICLQVKSCFEYTANPAGYNP 514
Query: 535 TIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFP--LVIKRQKSHQCQDFIVYLRDETE 592
+I ++ ++ + ++K + + N + + L +KRQK C + ++L+D
Sbjct: 515 SISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN-- 572
Query: 593 FRDKLSPINISLNYSLDESTFKEGL----EVKPILNYYRENIVSEQAHILVD-CGEDNLC 647
RDKL PI I+ + + E + + + EV PILN H L + CG+DN+C
Sbjct: 573 IRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVC 632
Query: 648 VPDLKLSAR-------PDKH----------QVIIGDENHLMLIINARN----------EG 680
+LKL + DK ++++ D+ + L I N +G
Sbjct: 633 NSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDG 692
Query: 681 EGAYEAELFVMIPEEADYVGIERNNKGF--RPLSCEYKMENVTRMVVCDLGNPMVSGTNY 738
+ A+EA+L P+ Y R + F + LSC C+LGNP +N
Sbjct: 693 DDAHEAKLIATFPDTLTYSAY-RELRAFPEKQLSCVANQNG--SQADCELGNPFKRNSNV 749
Query: 739 SLGLRFAVPRLEKTNMSINFDLQIRS-SNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQ 797
+ L + + ++ +L++ + SN+DN ++ + + + + GV+ P Q
Sbjct: 750 TFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAP--ITAKAKVVIELLLSVSGVAKPSQ 807
Query: 798 IVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGP--STISDTILEVGWPFS-ARDEFLL 854
+ E+ E+EVG L+E+ + + N+G + + L + WP + ++LL
Sbjct: 808 VYFG-GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLL 866
Query: 855 YIFHIQTLG--PLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVE 912
Y+ +++ G + C+P IN ++ + + E++ + D
Sbjct: 867 YLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITE----------KQIDDNRKFS 916
Query: 913 FHRQSPAKILNCT-NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASL 971
+ + LNC+ N+ C+ I C + L+ S +L RSRLW TFL+ + L L
Sbjct: 917 LFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDIL 974
Query: 972 VSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFS-IPLWVIILAILLGLLVLAILT 1030
+ + + +LP ++ +V + +S +P W+I++AIL G+L+LA+L
Sbjct: 975 MRAFIDVTAAAEN-IRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLV 1033
Query: 1031 LALWKCGFFDRARPPQEDMT-----------DREQLTND 1058
LWKCGFF R + D T D+E+LT+D
Sbjct: 1034 FILWKCGFFKRNKKDHYDATYHKAEIHAQPSDKERLTSD 1072
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 366 bits (940), Expect = e-101
Identities = 309/1093 (28%), Positives = 510/1093 (46%), Gaps = 122/1093 (11%)
Query: 20 LCCAAAALGMLLWSPACQAFNLDVEKLTVYS--GPKGSYFGYAVDFH--IPDARTASVLV 75
LC + G+L S AFNLD + V G GS FG+++ H + +LV
Sbjct: 7 LCLLYLSAGLL--SRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLV 64
Query: 76 GAPKANTSQPDIVEG-GAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQ 134
GAP+A G +Y C A G C +I FD N E K +Q
Sbjct: 65 GAPRAEALPLQRANRTGGLYSCDITARGP--CTRIEFD---------NDADPTSESKEDQ 113
Query: 135 WFGATVKAHK--GKVVACAPLYHWRTLKPTPE--KDPVGTCYVAIQNFSAY-----AEFS 185
W G TV++ GKVV CA Y R T + +D G CYV QN ++S
Sbjct: 114 WMGVTVQSQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWS 173
Query: 186 PCRNSNADPEGQGYCQAGFSLDFYKNGDLIV-GGPGSFYWQGQVITASVADIIANYS-FK 243
C E G CQ G + F K+ IV G PG++ W+G V + + + F+
Sbjct: 174 FCDGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFE 233
Query: 244 DILRKLAGEKQTEVAPASYD-DSYLGYSVAAGE-FTGDSQQELVAGIPRGAQNFGYVSI- 300
D ++ GE + + + +SYLG+S+ +G+ + V+G PR + V +
Sbjct: 234 DGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLK 293
Query: 301 --INSTDMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVG 358
+ S + F GE +AS FGY V V D+N DG D+++GAP + +R+ E G
Sbjct: 294 RDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVG----G 349
Query: 359 QIYLYLQVSSLLFR-DPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRG 417
+Y+Y+ P L GT+ FG A+ ++GD+NQDGY DIA+G P+ D G
Sbjct: 350 AVYVYMNQQGRWNNVKPIRLNGTKD-SMFGIAVKNIGDINQDGYPDIAVGAPY---DDLG 405
Query: 418 KVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGK 477
KV IY+G+ +G+NTKP+QVL+G+ FG+++ G+ D+D+N YPD+ VG+ +
Sbjct: 406 KVFIYHGSANGINTKPTQVLKGI------SPYFGYSIAGNMDLDRNSYPDVAVGSL-SDS 458
Query: 478 VAVYRARPVVTVDAQLLLHPMIINLENKT-CQVPDSMTSAACFSLRVCASVTGQSIAN-- 534
V ++R+RPV+ + + + P I+L KT C P S C ++ C T
Sbjct: 459 VTIFRSRPVINIQKTITVTPNRIDLRQKTACGAP----SGICLQVKSCFEYTANPAGYNP 514
Query: 535 TIVLMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFP--LVIKRQKSHQCQDFIVYLRDETE 592
+I ++ ++ + ++K + + N + + L +KRQK C + ++L+D
Sbjct: 515 SISIVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDN-- 572
Query: 593 FRDKLSPINISLNYSLDESTFKEGL----EVKPILNYYRENIVSEQAHILVD-CGEDNLC 647
RDKL PI I+ + + E + + + EV PILN H L + CG+DN+C
Sbjct: 573 IRDKLRPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVC 632
Query: 648 VPDLKLSAR-------PDKH----------QVIIGDENHLMLIINARN----------EG 680
+LKL + DK ++++ D+ + L I N +G
Sbjct: 633 NSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDG 692
Query: 681 EGAYEAELFVMIPEEADYVGIERNNKGF--RPLSCEYKMENVTRMVVCDLGNPMVSGTNY 738
+ A+EA+L P+ Y R + F + LSC C+LGNP +N
Sbjct: 693 DDAHEAKLIATFPDTLTYSAY-RELRAFPEKQLSCVANQNG--SQADCELGNPFKRNSNV 749
Query: 739 SLGLRFAVPRLEKTNMSINFDLQIRS-SNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQ 797
+ L + + ++ +L++ + SN+DN ++ + + + + GV+ P Q
Sbjct: 750 TFYLVLSTTEVTFDTPDLDINLKLETTSNQDNLAP--ITAKAKVVIELLLSVSGVAKPSQ 807
Query: 798 IVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGP--STISDTILEVGWPFS-ARDEFLL 854
+ E+ E+EVG L+E+ + + N+G + + L + WP + ++LL
Sbjct: 808 VYFG-GTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLL 866
Query: 855 YIFHIQTLG--PLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVE 912
Y+ +++ G + C+P IN ++ + + E++ + D
Sbjct: 867 YLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITE----------KQIDDNRKFS 916
Query: 913 FHRQSPAKILNCT-NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASL 971
+ + LNC+ N+ C+ I C + L+ S +L RSRLW TFL+ + L L
Sbjct: 917 LFAERKYQTLNCSVNVNCVNIRCPLRGLDSKASLIL--RSRLWNSTFLEEYSKLNYLDIL 974
Query: 972 VSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFS-IPLWVIILAILLGLLVLAILT 1030
+ + + +LP ++ +V + +S +P W+I++AIL G+L+LA+L
Sbjct: 975 MRAFIDVTAAAEN-IRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLV 1033
Query: 1031 LALWKCGFFDRAR 1043
LWKCGFF R+R
Sbjct: 1034 FILWKCGFFKRSR 1046
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 344 bits (883), Expect = 2e-94
Identities = 340/1167 (29%), Positives = 528/1167 (45%), Gaps = 174/1167 (14%)
Query: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA 60
M+ SR P G+ +C +L + L AFNLDV G GS FG++
Sbjct: 1 MAGARSRDPWGASG-----ICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFS 55
Query: 61 VDFH--IPDARTASVLVGAPKANTSQPDIVEG-GAVYYCPWPAEGSAQCRQIPFDTTNNR 117
V H + + +LVGAP+A G ++ CP E C ++ D
Sbjct: 56 VALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDID----- 109
Query: 118 KIRVNGTKEPIEFKSNQWFGATVKAHK--GKVVACAPLYHWRTL--KPTPEKDPVGTCYV 173
G E K NQW G +V++ GK+V CA Y R + +D +G C+V
Sbjct: 110 ----QGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFV 165
Query: 174 AIQNFSAY-----AEFSPCRNSNADPEGQGYCQAGFSLDFYKNGD-LIVGGPGSFYWQGQ 227
Q+ + E+ C E G+CQ G + F + L+ G PG++ W+G
Sbjct: 166 LSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGT 225
Query: 228 VITASVADIIANYS-FKDILRKLAGEKQTEV----APASYDDSYLGYSVAAGEFTGDSQQ 282
A A+ + D + GEK+ + PA+ SY G+S+ +G+ +++
Sbjct: 226 ARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPAN---SYFGFSIDSGKGLVRAEE 282
Query: 283 -ELVAGIPRGAQNFGYVSIINSTDMTFIQN---FTGEQMASYFGYTVVVSDVNSDGLDDV 338
VAG PR A + G V I+ + + +GE++ S FGY++ V+D+NSDG D+
Sbjct: 283 LSFVAGAPR-ANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDL 341
Query: 339 LVGAPLFMEREFESNPREVGQIYLYL-QVSSLLFRDPQILTGTETFGRFGSAMAHLGDLN 397
+VGAP F ER+ E G +Y+YL Q P L G+ FG ++A LGDLN
Sbjct: 342 IVGAPYFFERQEELG----GAVYVYLNQGGHWAGISPLRLCGSPD-SMFGISLAVLGDLN 396
Query: 398 QDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVP-SGFGFTLRG 456
QDG+ DIA+G PF G GKV IY+G+ G+ KPSQVL+G AV FG++L G
Sbjct: 397 QDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEG----EAVGIKSFGYSLSG 449
Query: 457 DSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSA 516
D+D N YPDL+VG+ V ++RARP++ V ++ + P I+LE C S+
Sbjct: 450 SLDMDGNQYPDLLVGSLADTAV-LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV--- 505
Query: 517 ACFSLRVCAS--VTGQSIANTIVLMAEVQLDSLKQ-KGAIKRTLFLD------NHQAHRV 567
C LRVC S S + T+ L + D+ ++ +G + R FL HQA
Sbjct: 506 -CVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGT 564
Query: 568 FPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFK-----EGL-EVKP 621
+ +K Q C D + L++ +DKL I ++L+YSL + +GL V P
Sbjct: 565 --VWLKHQHDRVCGDAMFQLQENV--KDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAP 620
Query: 622 ILNYYRENIVSEQAHILVD-CGEDNLCVPDLKL-------------------------SA 655
ILN ++ + + H L CGED +C +L+L +
Sbjct: 621 ILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTAL 680
Query: 656 RPDKHQVIIGDENHLMLIIN-------ARNEGEGAYEAELFVMIPEEADYVGIERNNKGF 708
Q +IG E +++ N + +G+ A+EA+L VM+P+ Y G+ +
Sbjct: 681 FALSGQPVIGLE---LMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAE 737
Query: 709 RPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVP--RLEKTNMSINFDLQIRSSN 766
+PL EN + V C+LGNPM G + L + +E T + + L S
Sbjct: 738 KPLC--LSNENASH-VECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 794
Query: 767 KDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYE 826
+ +P VS + + + I G++ P Q+ E E +VG V++
Sbjct: 795 ELHP----VSARARVFIELPLSIAGMAIPQQLFFS-GVVRGERAMQSERDVGSKVKYEVT 849
Query: 827 LHNIGPS--TISDTILEVGWPFS-ARDEFLLYIFHIQT---LGPLQ---CQPNPNI---- 873
+ N G S T+ L + WP A ++LLY ++ GP Q C P PNI
Sbjct: 850 VSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLD 909
Query: 874 ------NPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCT-- 925
++++P E + + +K+++ L+C
Sbjct: 910 VDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI------------TLDCARG 957
Query: 926 NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQP 985
C+ SC + + +AVL V RLW TFL+ + +L +V + + + +
Sbjct: 958 TANCVVFSCPLYSFD--RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKN 1014
Query: 986 AKLPEGSIAIKTSVIWATPN--VSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRAR 1043
L + S I +++ P V+ +P WVI+LA+L GLLVLA+L L LWK GFF RA+
Sbjct: 1015 LMLRDASTVIPV-MVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1073
Query: 1044 PPQEDM----------TDREQLTNDKT 1060
P+ + DR+Q +KT
Sbjct: 1074 HPEATVPQYHAVKIPREDRQQFKEEKT 1100
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 343 bits (880), Expect = 5e-94
Identities = 337/1165 (28%), Positives = 525/1165 (45%), Gaps = 174/1165 (14%)
Query: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA 60
M+ SR P G+ +C +L + L AFNLDV G GS FG++
Sbjct: 1 MAGARSRDPWGASG-----ICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFS 55
Query: 61 VDFH--IPDARTASVLVGAPKANTSQPDIVEG-GAVYYCPWPAEGSAQCRQIPFDTTNNR 117
V H + + +LVGAP+A G ++ CP E C ++ D
Sbjct: 56 VALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDID----- 109
Query: 118 KIRVNGTKEPIEFKSNQWFGATVKAHK--GKVVACAPLYHWRTL--KPTPEKDPVGTCYV 173
G E K NQW G +V++ GK+V CA Y R + +D +G C+V
Sbjct: 110 ----QGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFV 165
Query: 174 AIQNFSAY-----AEFSPCRNSNADPEGQGYCQAGFSLDFYKNGD-LIVGGPGSFYWQGQ 227
Q+ + E+ C E G+CQ G + F + L+ G PG++ W+G
Sbjct: 166 LSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGL 225
Query: 228 VITASVADIIAN---YSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQ-E 283
+ ++ + Y D +L G +SYLG+S+ +G+ +++
Sbjct: 226 LFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLAL-----NSYLGFSIDSGKGLVRAEELS 280
Query: 284 LVAGIPRGAQNFGYVSIINSTDMTFIQN---FTGEQMASYFGYTVVVSDVNSDGLDDVLV 340
VAG PR A + G V I+ + + +GE++ S FGY++ V+D+NSDG D++V
Sbjct: 281 FVAGAPR-ANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIV 339
Query: 341 GAPLFMEREFESNPREVGQIYLYL-QVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQD 399
GAP F ER+ E G +Y+YL Q P L G+ FG ++A LGDLNQD
Sbjct: 340 GAPYFFERQEELG----GAVYVYLNQGGHWAGISPLRLCGSPD-SMFGISLAVLGDLNQD 394
Query: 400 GYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVP-SGFGFTLRGDS 458
G+ DIA+G PF G GKV IY+G+ G+ KPSQVL+G AV FG++L G
Sbjct: 395 GFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEG----EAVGIKSFGYSLSGSL 447
Query: 459 DIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAAC 518
D+D N YPDL+VG+ V ++RARP++ V ++ + P I+LE C S+ C
Sbjct: 448 DMDGNQYPDLLVGSLADTAV-LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----C 502
Query: 519 FSLRVCAS--VTGQSIANTIVLMAEVQLDSLKQ-KGAIKRTLFLD------NHQAHRVFP 569
LRVC S S + T+ L + D+ ++ +G + R FL HQA
Sbjct: 503 VDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGT-- 560
Query: 570 LVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFK-----EGL-EVKPIL 623
+ +K Q C D + L++ +DKL I ++L+YSL + +GL V PIL
Sbjct: 561 VWLKHQHDRVCGDAMFQLQENV--KDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL 618
Query: 624 NYYRENIVSEQAHILVD-CGEDNLCVPDLKL-------------------------SARP 657
N ++ + + H L CGED +C +L+L +
Sbjct: 619 NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFA 678
Query: 658 DKHQVIIGDENHLMLIIN-------ARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRP 710
Q +IG E +++ N + +G+ A+EA+L VM+P+ Y G+ + +P
Sbjct: 679 LSGQPVIGLE---LMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKP 735
Query: 711 LSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVP--RLEKTNMSINFDLQIRSSNKD 768
L EN + V C+LGNPM G + L + +E T + + L S +
Sbjct: 736 LC--LSNENASH-VECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQEL 792
Query: 769 NPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELH 828
+P VS + + + I G++ P Q+ E E +VG V++ +
Sbjct: 793 HP----VSARARVFIELPLSIAGMAIPQQLFFS-GVVRGERAMQSERDVGSKVKYEVTVS 847
Query: 829 NIGPS--TISDTILEVGWPFS-ARDEFLLYIFHIQT---LGPLQ---CQPNPNI------ 873
N G S T+ L + WP A ++LLY ++ GP Q C P PNI
Sbjct: 848 NQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVD 907
Query: 874 ----NPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCT--NI 927
++++P E + + +K+++ L+C
Sbjct: 908 SRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI------------TLDCARGTA 955
Query: 928 ECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAK 987
C+ SC + + +AVL V RLW TFL+ + +L +V + + + +
Sbjct: 956 NCVVFSCPLYSFD--RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLM 1012
Query: 988 LPEGSIAIKTSVIWATPN--VSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARPP 1045
L + S I +++ P V+ +P WVI+LA+L GLLVLA+L L LWK GFF RA+ P
Sbjct: 1013 LRDASTVIPV-MVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 1071
Query: 1046 QEDM----------TDREQLTNDKT 1060
+ + DR+Q +KT
Sbjct: 1072 EATVPQYHAVKIPREDRQQFKEEKT 1096
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 312 bits (799), Expect = 1e-84
Identities = 278/1054 (26%), Positives = 470/1054 (44%), Gaps = 111/1054 (10%)
Query: 29 MLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKAN-TSQPDI 87
+ L P + +N+D E +Y GP + FGY+V H A +LVGAP AN + +
Sbjct: 24 LCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRW-LLVGAPTANWLANASV 82
Query: 88 VEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEPIEFKSNQWFGATVK---AHK 144
+ GA+Y C C Q+ + N K +E + NQW G T+
Sbjct: 83 INPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCG----KTCLEERDNQWLGVTLSRQPGEN 138
Query: 145 GKVVACAPLYHWRTLK--PTPEKDPVGTCYVAIQNFSAYAE--FSPCRNSNADPEGQGY- 199
G +V C + W+ + K P G CY + +PC G+ +
Sbjct: 139 GSIVTCG--HRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQDYVKKFGENFA 196
Query: 200 -CQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVA 258
CQAG S FY +++G PGS YW G + + I +K L +KQ +V
Sbjct: 197 SCQAGIS-SFYTKDLIVMGAPGSSYWTGSLFVYN----ITTNKYKAFL-----DKQNQVK 246
Query: 259 PASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQ-NFGYVSIINSTDMTFIQNFTGEQM 317
SY LGYSV AG F E+V G P+ Q Y+ I+ ++ + G+++
Sbjct: 247 FGSY----LGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKL 302
Query: 318 ASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYLQVSS--LLFRDPQ 375
SYFG +V D+N+DG D+LVGAP+ +S RE G++++Y+ S ++
Sbjct: 303 GSYFGASVCAVDLNADGFSDLLVGAPM------QSTIREEGRVFVYINSGSGAVMNAMET 356
Query: 376 ILTGTETF-GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPS 434
L G++ + RFG ++ +LGD++ DG+ D+AIG P D +G + IYNG DG+++ S
Sbjct: 357 NLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAP-QEDDLQGAIYIYNGRADGISSTFS 415
Query: 435 QVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLL 494
Q ++G+ S ++ S FG ++ G D D N Y D+ VGAF + + R RPVV VDA L
Sbjct: 416 QRIEGLQISKSL-SMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDAS-L 473
Query: 495 LHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAIK 554
HP +N C ++ + C L +C S G+ + IVL + LD ++ +
Sbjct: 474 SHPESVNRTKFDC--VENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESPP 531
Query: 555 RTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSL-----D 609
R F N + + + + C+ ++R + RD L+PI I Y L
Sbjct: 532 RFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDV--RDILTPIQIEAAYHLGPHVIS 589
Query: 610 ESTFKEGLEVKPILNYYRE-NIVSEQAHILVDCGEDNLCVPDLKLSAR-------PDKHQ 661
+ + +E ++PIL +E +I+ + + C +N C DL++SA+ +K
Sbjct: 590 KRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN-CSADLQVSAKIGFLKPHENKTY 648
Query: 662 VIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVT 721
+ +G LML ++ N G+ AYE L V +P ++ I + + ++CE +
Sbjct: 649 LAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEE--KQINCEVTDNSGV 706
Query: 722 RMVVCDLGNPMVSG-TNYSLGLRFAVPRLEKTNMSINFDLQIRSSNK---DNPDSNFVSL 777
+ C +G V + + V L + ++ + N+ DN + V++
Sbjct: 707 VQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTV 766
Query: 778 QINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISD 837
I + ++ + G +P V N E E E E++ L H+ N G S +
Sbjct: 767 AIPLKYEVKLTVHGFVNPTSFVYG-SNDENEPETCMVEKMN-LTFHVI---NTGNSMAPN 821
Query: 838 TILEVGWP--FSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLR 895
+E+ P FS + + L I +QT + ++ + + E L+
Sbjct: 822 VSVEIMVPNSFSPQTDKLFNILDVQT-------TTGECHFENYQRVCALEQQKSAMQTLK 874
Query: 896 NSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIE--CLQISCAVGRLEGGESAVLKVRSRL 953
+V F ++ ++L C + CL C G++E G+ A V +L
Sbjct: 875 G-------------IVRFLSKTDKRLLYCIKADPHCLNFLCNFGKMESGKEA--SVHIQL 919
Query: 954 WAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPE------GSIAIKTSVIWATPNVS 1007
+ ++ AL FE++ + + ++ E + + + P
Sbjct: 920 EGRPSILEMDETSAL----KFEIRATGFPEPNPRVIELNKDENVAHVLLEGLHHQRPKRY 975
Query: 1008 FSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
F+I +I ++LLGL+VL +++ +WK GFF R
Sbjct: 976 FTIV--IISSSLLLGLIVLLLISYVMWKAGFFKR 1007
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 304 bits (779), Expect = 3e-82
Identities = 292/996 (29%), Positives = 460/996 (46%), Gaps = 152/996 (15%)
Query: 165 KDPVGTCYVAIQNFSAY-----AEFSPCRNSNADPEGQGYCQAGFSLDFYKNGD-LIVGG 218
+D +G C+V Q+ + E+ C E G+CQ G + F + L+ G
Sbjct: 60 RDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGA 119
Query: 219 PGSFYWQGQVITASVADIIANYS-FKDILRKLAGEKQTEV----APASYDDSYLGYSVAA 273
PG++ W+G A A+ + D + GEK+ + PA+ SY G+S+ +
Sbjct: 120 PGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPAN---SYFGFSIDS 176
Query: 274 GEFTGDSQQ-ELVAGIPRGAQNFGYVSIINSTDMTFIQN---FTGEQMASYFGYTVVVSD 329
G+ +++ VAG PR A + G V I+ + + +GE++ S FGY++ V+D
Sbjct: 177 GKGLVRAEELSFVAGAPR-ANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVAD 235
Query: 330 VNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYL-QVSSLLFRDPQILTGTETFGRFGS 388
+NSDG D++VGAP F ER+ E G +Y+YL Q P L G+ FG
Sbjct: 236 LNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHWAGISPLRLCGSPD-SMFGI 290
Query: 389 AMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVP- 447
++A LGDLNQDG+ DIA+G PF G GKV IY+G+ G+ KPSQVL+G AV
Sbjct: 291 SLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEG----EAVGI 343
Query: 448 SGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTC 507
FG++L G D+D N YPDL+VG+ V ++RARP++ V ++ + P I+LE C
Sbjct: 344 KSFGYSLSGSLDMDGNQYPDLLVGSLADTAV-LFRARPILHVSHEVSIAPRSIDLEQPNC 402
Query: 508 QVPDSMTSAACFSLRVCAS--VTGQSIANTIVLMAEVQLDSLKQ-KGAIKRTLFLD---- 560
S+ C LRVC S S + T+ L + D+ ++ +G + R FL
Sbjct: 403 AGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLE 458
Query: 561 --NHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFK---- 614
HQA + +K Q C D + L++ +DKL I ++L+YSL +
Sbjct: 459 EPKHQASGT--VWLKHQHDRVCGDAMFQLQENV--KDKLRAIVVTLSYSLQTPRLRRQAP 514
Query: 615 -EGL-EVKPILNYYRENIVSEQAHILVD-CGEDNLCVPDLKL------------------ 653
+GL V PILN ++ + + H L CGED +C +L+L
Sbjct: 515 GQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLP 574
Query: 654 -------SARPDKHQVIIGDENHLMLIIN-------ARNEGEGAYEAELFVMIPEEADYV 699
+ Q +IG E +++ N + +G+ A+EA+L VM+P+ Y
Sbjct: 575 MDVDGTTALFALSGQPVIGLE---LMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYS 631
Query: 700 GIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVP--RLEKTNMSIN 757
G+ + +PL EN + V C+LGNPM G + L + +E T + +
Sbjct: 632 GVRALDPAEKPLC--LSNENASH-VECELGNPMKRGAQVTFYLILSTSGISIETTELEVE 688
Query: 758 FDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEV 817
L S + +P VS + + + I G++ P Q+ E E +V
Sbjct: 689 LLLATISEQELHP----VSARARVFIELPLSIAGMAIPQQLFFS-GVVRGERAMQSERDV 743
Query: 818 GPLVEHIYELHNIGPS--TISDTILEVGWPFS-ARDEFLLYIFHIQT---LGPLQ---CQ 868
G V++ + N G S T+ L + WP A ++LLY ++ GP Q C
Sbjct: 744 GSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCS 803
Query: 869 PNPNI----------NPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSP 918
P PNI ++++P E + + +K+++
Sbjct: 804 PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI---------- 853
Query: 919 AKILNCT--NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEV 976
L+C C+ SC + + +AVL V RLW TFL+ + +L +V +
Sbjct: 854 --TLDCARGTANCVVFSCPLYSFD--RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANI 909
Query: 977 KKMPYTDQPAKLPEGSIAIKTSVIWATPN--VSFSIPLWVIILAILLGLLVLAILTLALW 1034
+ + + L + S I +++ P V+ +P WVI+LA+L GLLVLA+L L LW
Sbjct: 910 -TVKSSIKNLMLRDASTVIPV-MVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 967
Query: 1035 KCGFFDRARPPQEDM----------TDREQLTNDKT 1060
K GFF RA+ P+ + DR+Q +KT
Sbjct: 968 KMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKT 1003
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 300 bits (768), Expect = 5e-81
Identities = 300/1093 (27%), Positives = 479/1093 (43%), Gaps = 141/1093 (12%)
Query: 3 PGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVD 62
P A RG +A L+A L A G A+NLD ++ + GP S+FGYAV
Sbjct: 4 PAAPRGAGRLRALLLA-LVVAGIPAG---------AYNLDPQRPVHFQGPADSFFGYAVL 53
Query: 63 FHIPDARTASVLVGAPKANTS-QPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRV 121
H D T VLVGAPKA++ P + GAV+ C +C ++ NR
Sbjct: 54 EHFHD-NTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSC 112
Query: 122 NGTKEPIEFKSNQWFGATVKAHK---GKVVACAPLYHWRTLKPTPEKD-PVGTCYVAIQN 177
T E + ++W G ++ G+V+ACA + W+ + + P G CY+ N
Sbjct: 113 GKTCR--EDRDDEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSN 168
Query: 178 FSAYAE-FSPCRNSNADPEGQ--GYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVA 234
A PC G+ G CQAG + F+ +++G PGSFYW G T V
Sbjct: 169 LQAKGRTLIPCYEEYKKKYGEEHGSCQAGIA-GFFTEELVVMGAPGSFYWAG---TIKVL 224
Query: 235 DIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQN 294
++ N K + + T YLGY+V AG F+ S ++V G P+ +
Sbjct: 225 NLTDNTYLKLNDEVIMNRRYT----------YLGYAVTAGHFSHPSTIDVVGGAPQD-KG 273
Query: 295 FGYVSIINSTDM--TFIQNF--TGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREF 350
G V I + T I+ F +G++M SYFG ++ D+N DGL D+LVGAP+F E
Sbjct: 274 IGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEI-- 331
Query: 351 ESNPREVGQIYLYLQVSSLLFRDPQILTGTETFG-RFGSAMAHLGDLNQDGYNDIAIGVP 409
R+ GQ+ +Y+ + + LTG + FG ++A L DL+ DG+ D+AIG P
Sbjct: 332 ----RDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAP 387
Query: 410 FAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLI 469
D G V IY+G+ G+ + S L G + V FG ++ G D+D N YPD+
Sbjct: 388 -KEDDFAGAVYIYHGDAGGIVPQYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVT 445
Query: 470 VGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTG 529
VGAF + V + RARPV+TVD + L P IN+ C D C ++ C S G
Sbjct: 446 VGAFMSDSVVLLRARPVITVDVSIFL-PGSINITAPQCH--DGQQPVNCLNVTTCFSFHG 502
Query: 530 QSIANTI----VLMAEVQLDSLKQKGAIKRTLF-LDNHQAHRVFPLVIKRQKSHQCQDFI 584
+ + I VLMA+V + K+KG + R F L +V + C+ ++
Sbjct: 503 KHVPGEIGLNYVLMADV---AKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYV 559
Query: 585 VYLRDETEFRDKLSPINISLNYSLDES-TFKEGLEVKPILNYYR----------ENIVSE 633
+++ + D +SPI YSL E T +E E+ P+ R V E
Sbjct: 560 AHVKRRVQ--DVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFE 617
Query: 634 QAHILVDCGEDNLCVPDLKLSARPDKH-QVIIGDENHLMLIINARNEGEGAYEAELFVMI 692
+ DC D L LS+ +K + +G ++ L I+ N G+ AY+A + +
Sbjct: 618 RNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNV 677
Query: 693 PEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNP-MVSGTNYSLGLRFAVPRLEK 751
E ++ + + + +SCE + + C +G P M S + Y + F L
Sbjct: 678 SRELFFINMWQKEE--MGISCELLESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSG 732
Query: 752 TNMSINFDLQIRSSNKDNPDS---NFVSLQINITAVAQVEIRGVSHPPQIV--------- 799
++F + +S N + +S N + L + + I G+ P V
Sbjct: 733 EEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAAN 792
Query: 800 -LPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFH 858
+ + + E +P + +++N GPST+ + + + +P + +FH
Sbjct: 793 FIQLDDLECHFQP---------INITLQVYNTGPSTLPGSSVSISFP-NRLSSGGAEMFH 842
Query: 859 IQTL------GPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVE 912
+Q + G Q NP P P++ I H +
Sbjct: 843 VQEMVVGQEKGNCSFQKNPT-------PCIIPQE---------QENIFHT-------IFA 879
Query: 913 FHRQSPAKILNC--TNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALAS 970
F +S K+L+C I CL C L ES + + L +T + +K+ +
Sbjct: 880 FFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLL--NTEILKKDSSSVIQF 937
Query: 971 LVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVS--FSIPLWVIILAILLGLLVLAI 1028
+ +VK P + ++ G+ T V A N+ + W+I +++L+G+L+ +
Sbjct: 938 MSRAKVKVDPAL-RVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLL 996
Query: 1029 LTLALWKCGFFDR 1041
L + LWK GFF R
Sbjct: 997 LAVLLWKMGFFRR 1009
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 289 bits (740), Expect = 8e-78
Identities = 307/1106 (27%), Positives = 491/1106 (44%), Gaps = 146/1106 (13%)
Query: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVY-SGPKGSYFGY 59
M PG SR PR + L A L AA G ++ AFNLD L V +G GS FGY
Sbjct: 1 MGPGPSRAPRAPRLMLCA-LALMVAAGGCVV-----SAFNLDTRFLVVKEAGNPGSLFGY 54
Query: 60 AVDFHIPDARTAS--VLVGAPKANTSQPDIVEG--GAVYYCPWPAEGSAQCRQIPFDTTN 115
+V H R +L GAP+ + PD GAVY CP A C ++ N
Sbjct: 55 SVALHRQTERQQRYLLLAGAPR-ELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKN 112
Query: 116 NRKIRVNGTKEPIEFKSNQWFGATVKAH--KGKVVACAPLYH---WRTLKPTPEKDPVGT 170
+ + IE + W G TV + G+V+ CA Y W + ++ VG
Sbjct: 113 DPGHHI------IE---DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSED--QRRMVGK 161
Query: 171 CYVAIQNFSAYAE------FSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYW 224
CYV + + + NSN D G CQ G S F +N + G PG++ W
Sbjct: 162 CYVRGNDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQN-TVYFGAPGAYNW 220
Query: 225 QGQ--VITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQ 282
+G +I D+ + YS+KD P + Y+GY++ G F +
Sbjct: 221 KGNSYMIQRKEWDL-SEYSYKD--------------PEDQGNLYIGYTMQVGSFILHPKN 265
Query: 283 -ELVAGIPRGAQNFGYVSIINST---DMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDV 338
+V G PR ++ G V +++ D+ Q G Q+ +YFG + ++D+N+DG D+
Sbjct: 266 ITIVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDL 324
Query: 339 LVGAPLFMEREFESNPREVGQIYLYLQVSSLLF-RDPQILTGTETFGRFGSAMAHLGDLN 397
LVGAP + ER+ E G IY+++ + F P +L + FG ++A +GD+N
Sbjct: 325 LVGAPYYFERKEEVG----GAIYVFMNQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDIN 380
Query: 398 QDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGD 457
QDG+ DIA+G PF G GKV IY+ + GL +P QV+ G + FG++L G
Sbjct: 381 QDGFQDIAVGAPFEGL---GKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ 437
Query: 458 SDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLL-HPMIINLENKTCQVPDSMTSA 516
D+D+N YPDL+VG+ + + + RARPV+ + + L+ P +++ P T+
Sbjct: 438 MDVDENFYPDLLVGSL-SDHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTAT 488
Query: 517 ACFSLRVCASVTGQSIAN-----TIVLMAEVQLDSLKQKGAIKRTLFLDNHQA--HRVFP 569
+C + +C + QS N I L ++ D ++ ++ F + A H F
Sbjct: 489 SCVQVELCFAYN-QSAGNPNYRRNITLAYTLEADRDRRPPRLR---FAGSESAVFHGFFS 544
Query: 570 LVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLD------ESTFKEGLEVKPIL 623
+ R CQ + L D RDKL PI IS+NYSL L+ PIL
Sbjct: 545 MPEMR-----CQKLELLLMDN--LRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPIL 597
Query: 624 NYYRENIVSEQAHILVDCGEDNLCVPDLKLSAR--PDKHQVIIG-----DENHLMLIINA 676
N + + +CG DN C +L++ A ++ Q + D L+L IN
Sbjct: 598 NQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINV 657
Query: 677 RN------EGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGN 730
N GE A+EA L +++P + P +C+ + C+LGN
Sbjct: 658 TNTRTSERSGEDAHEALLTLVVPPALLLSSVRP------PGACQ-----ANETIFCELGN 706
Query: 731 PMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIR-SSNKDNPDSNFVSLQINITAVAQVEI 789
P L + F V + + LQ+ SS++DN ++L ++ T Q +
Sbjct: 707 PFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYTL--QTSL 764
Query: 790 RGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVG--WPFS 847
V+H Q E E+VG +++ +++ +G + L +G WP+
Sbjct: 765 SMVNHRLQSFFG-GTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYE 823
Query: 848 ARD-EFLLYIFHIQTLG--PLQCQPNPN-INPQDIKPAASPEDTPELSAFLRNSTIPHLV 903
+ ++LLY I G C+P + INP ++ + P D P R P
Sbjct: 824 VSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLT-LSDPGDRPSSPQRRRRQLDPGGG 882
Query: 904 R-KRDVHVVEFHRQSPAKILNCTN--IECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQ 960
+ V + + +L C C+ + C + + + V++R+W TF++
Sbjct: 883 QGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIE 940
Query: 961 --RKNDPYALASLVSFEVK-KMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIIL 1017
R D + + ++ +P + K S+ I + ++ P I LW++++
Sbjct: 941 DYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPA---EIELWLVLV 997
Query: 1018 AILLGLLVLAILTLALWKCGFFDRAR 1043
A+ GLL+L ++ L LWKCGFF RAR
Sbjct: 998 AVGAGLLLLGLIILLLWKCGFFKRAR 1023
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 285 bits (729), Expect = 2e-76
Identities = 304/1105 (27%), Positives = 485/1105 (43%), Gaps = 144/1105 (13%)
Query: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVY-SGPKGSYFGY 59
M PG SR PR + L A L AA G ++ AFNLD L V +G GS FGY
Sbjct: 1 MGPGPSRAPRAPRLMLCA-LALMVAAGGCVV-----SAFNLDTRFLVVKEAGNPGSLFGY 54
Query: 60 AVDFHIPDARTAS--VLVGAPKANTSQPDIVEG--GAVYYCPWPAEGSAQCRQIPFDTTN 115
+V H R +L GAP+ + PD GAVY CP A C ++ N
Sbjct: 55 SVALHRQTERQQRYLLLAGAPR-ELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKN 112
Query: 116 NRKIRVNGTKEPIEFKSNQWFGATVKAH--KGKVVACAPLYH---WRTLKPTPEKDPVGT 170
+ + IE + W G TV + G+V+ CA Y W + ++ VG
Sbjct: 113 DPGHHI------IE---DMWLGVTVASQGPAGRVLVCAHRYTQVLWSGSED--QRRMVGK 161
Query: 171 CYVAIQNFSAYAE------FSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYW 224
CYV + + + NSN D G CQ G S F +N + G PG++ W
Sbjct: 162 CYVRGNDLELDSSDDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQN-TVYFGAPGAYNW 220
Query: 225 QGQ--VITASVADIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQ 282
+G +I D+ + YS+KD P + Y+GY++ G F +
Sbjct: 221 KGNSYMIQRKEWDL-SEYSYKD--------------PEDQGNLYIGYTMQVGSFILHPKN 265
Query: 283 -ELVAGIPRGAQNFGYVSIINST---DMTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDV 338
+V G PR ++ G V +++ D+ Q G Q+ +YFG + ++D+N+DG D+
Sbjct: 266 ITIVTGAPRH-RHMGAVFLLSQEAGGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDL 324
Query: 339 LVGAPLFMEREFESNPREVGQIYLYLQVSSLLF-RDPQILTGTETFGRFGSAMAHLGDLN 397
LVGAP + ER+ E G IY+++ + F P +L + FG ++A +GD+N
Sbjct: 325 LVGAPYYFERKEEVG----GAIYVFMNQAGTSFPAHPSLLLHGPSGSAFGLSVASIGDIN 380
Query: 398 QDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGD 457
QDG+ DIA+G PF G GKV IY+ + GL +P QV+ G + FG++L G
Sbjct: 381 QDGFQDIAVGAPFEG---LGKVYIYHSSSKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQ 437
Query: 458 SDIDKNDYPDLIVGAFGTGKVAVYRARPVVT-VDAQLLLHPMIINLENKTCQVPDSMTSA 516
D+D+N YPDL+VG+ + + + RARPV+ V L+ P +++ P T+
Sbjct: 438 MDVDENFYPDLLVGSL-SDHIVLLRARPVINIVHKTLVPRPAVLD--------PALCTAT 488
Query: 517 ACFSLRVC----ASVTGQSIANTIVLMAEVQLDSLKQKGAIKRTLFLDNHQA--HRVFPL 570
+C + +C S + I L ++ D ++ R F + A H F +
Sbjct: 489 SCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRRP---PRLRFAGSESAVFHGFFSM 545
Query: 571 VIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLD------ESTFKEGLEVKPILN 624
R CQ + L D RDKL PI IS+NYSL L+ PILN
Sbjct: 546 PEMR-----CQKLELLLMD--NLRDKLRPIIISMNYSLPLRMPDRPRLGLRSLDAYPILN 598
Query: 625 YYRENIVSEQAHILVDCGEDNLCVPDLKLSAR--PDKHQVI-----IGDENHLMLIINAR 677
+ + +CG DN C +L++ A ++ Q + D L+L IN
Sbjct: 599 QAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVT 658
Query: 678 N------EGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNP 731
N GE A+EA L +++P + P +C+ + C+LGNP
Sbjct: 659 NTRTSERSGEDAHEALLTLVVPPALLLSSVR------PPGACQ-----ANETIFCELGNP 707
Query: 732 MVSGTNYSLGLRFAVPRLEKTNMSINFDLQI-RSSNKDNPDSNFVSLQINITAVAQVEIR 790
L + F V + + LQ+ SS++DN ++L ++ T Q +
Sbjct: 708 FKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNLWPMILTLLVDYT--LQTSLS 765
Query: 791 GVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTI--SDTILEVGWPFS- 847
V+H Q E E+VG +++ +++ +G + +L + WP+
Sbjct: 766 MVNHRLQSFFG-GTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVGLGTLVLGLEWPYEV 824
Query: 848 ARDEFLLYIFHIQT--LGPLQCQPNPN-INPQDIKPAASPEDTPELSAFLRNSTIPHLVR 904
+ ++LLY I G C+P + INP ++ + P D P R P +
Sbjct: 825 SNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNL-TLSDPGDRPSSPQRRRRQLDPGGGQ 883
Query: 905 -KRDVHVVEFHRQSPAKILNCT--NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQ- 960
V + + +L C C+ + C + + + V++R+W TF++
Sbjct: 884 GPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIP--DAPVVTNVTVKARVWNSTFIED 941
Query: 961 -RKNDPYALASLVSFEVK-KMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILA 1018
R D + + ++ +P + K S+ I + ++ P I LW++++A
Sbjct: 942 YRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELP---AEIELWLVLVA 998
Query: 1019 ILLGLLVLAILTLALWKCGFFDRAR 1043
+ GLL+L ++ L LWKC FF R R
Sbjct: 999 VGAGLLLLGLIILLLWKCDFFKRTR 1023
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 223 bits (569), Expect = 6e-58
Identities = 235/886 (26%), Positives = 378/886 (42%), Gaps = 149/886 (16%)
Query: 201 QAGFSLDFYKNGD-LIVGGPGSFYWQGQVI--TASVADIIANYSFKDILRKLAGEKQTEV 257
Q GFS D+ D L++G G+F W G ++ T+ I +F IL+
Sbjct: 380 QVGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQD--------- 430
Query: 258 APASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYV--SIINSTDMTFIQNFTGE 315
SYLGYSVAA TG+S VAG PR V S+ + ++T IQ G+
Sbjct: 431 ---RNHSSYLGYSVAAIS-TGESTH-FVAGAPRANYTGQIVLYSVNENGNITVIQAHRGD 485
Query: 316 QMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDP 374
Q+ SYFG + DV+ D + DVL VGAP++M +E G++YL+ +L +
Sbjct: 486 QIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMS----DLKKEEGRVYLFTIKEGILGQH- 540
Query: 375 QILTGTETFG--RFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTK 432
Q L G E RFGSA+A L D+N DG+ND+ +G P ++ G V IYNG++ + TK
Sbjct: 541 QFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNS-GAVYIYNGHQGTIRTK 599
Query: 433 PSQVL---QGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTV 489
SQ + G + SH FG +L G D++ + D+ +GAF G+V ++ + V
Sbjct: 600 YSQKILGSDGAFRSHL--QYFGRSLDGYGDLNGDSITDVSIGAF--GQVVQLWSQSIADV 655
Query: 490 DAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQ 549
+ P I L NK Q+ CFS + + +A IV + D
Sbjct: 656 AIEASFTPEKITLVNKNAQI----ILKLCFSAKFRPTKQNNQVA--IVYNITLDADGFSS 709
Query: 550 KGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLD 609
+ R LF +N++ +V+ + +S C + I+Y+++ + D ++ +++ ++ SL
Sbjct: 710 R-VTSRGLFKENNERCLQKNMVVNQAQS--CPEHIIYIQEPS---DVVNSLDLRVDISL- 762
Query: 610 ESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSAR----PDKHQVIIG 665
E P L Y E DCGED LC+ DL L R + I+
Sbjct: 763 -----ENPGTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVS 817
Query: 666 DEN-HLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENVTRMV 724
++N L + +N+ E AY + V E + G ++C+ + V
Sbjct: 818 NQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDG-TEVTCQVAASQ--KSV 874
Query: 725 VCDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRS--------------SNKDNP 770
CD+G P A+ R ++ +INFD +++ S ++N
Sbjct: 875 ACDVGYP-------------ALKREQQVTFTINFDFNLQNLQNQASLSFQALSESQEENK 921
Query: 771 DSNFVSLQINITAVAQV-----------EIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGP 819
N V+L+I + A++ EI + P IV H E+VGP
Sbjct: 922 ADNLVNLKIPLLYDAEIHLTRSTNINFYEISSDGNVPSIV------------HSFEDVGP 969
Query: 820 LVEHIYELH-NIGPSTISDTILEVGWP-FSARDEFLLYIFHIQT--LGPLQCQPNPNINP 875
+ I+ L G +S + + P ++ L+Y+ +QT G + C N +INP
Sbjct: 970 --KFIFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQTDKAGDISC--NADINP 1025
Query: 876 QDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCA 935
I +S S ++ H K LNC C ++C
Sbjct: 1026 LKIGQTSS-------SVSFKSENFRH-----------------TKELNCRTASCSNVTCW 1061
Query: 936 VGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAI 995
+ + + V +R+W TF L + Y + + + ++ I
Sbjct: 1062 LKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINT----YNPEIYVIEDNTVTI 1117
Query: 996 KTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
++ P+ +P VII +I+ G+L+L L LWK GFF R
Sbjct: 1118 PLMIM--KPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKR 1161
Score = 45.4 bits (106), Expect = 3e-04
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 20/181 (11%)
Query: 8 GPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD 67
GP + A + L A + G+L C A+N+ + + ++SGP FGYAV I +
Sbjct: 2 GPERTGAAPLPLLLVLALSQGIL---NCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFI-N 57
Query: 68 ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGTKEP 127
+ +LVG+P + + + G VY CP +A C ++ T+ +
Sbjct: 58 PKGNWLLVGSPWSGFPENRM---GDVYKCPVDL-STATCEKLNLQTSTS-------IPNV 106
Query: 128 IEFKSNQWFGATVKAHKGK--VVACAPLYHWRTLKPTPEKDPVGTCYVAIQNFSAYAEFS 185
E K+N G + + G + C PL+ + + G C +F A FS
Sbjct: 107 TEMKTNMSLGLILTRNMGTGGFLTCGPLW---AQQCGNQYYTTGVCSDISPDFQLSASFS 163
Query: 186 P 186
P
Sbjct: 164 P 164
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 192 bits (489), Expect = 1e-48
Identities = 220/885 (24%), Positives = 375/885 (42%), Gaps = 136/885 (15%)
Query: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260
Q GFS Y +++G G++ W G V+ + II ++ + K+ E
Sbjct: 379 QTGFSAH-YSQDWVMLGAVGAYDWNGTVVMQKASQIIIP---RNTTFNVESTKKNEPLA- 433
Query: 261 SYDDSYLGYSVAAGEFTGDSQQEL-VAGIPRGAQNFGYVSIINSTD--MTFIQNFTGEQM 317
SYLGY+V + T S L +AG PR + G V I D + +Q +GEQ+
Sbjct: 434 ----SYLGYTVNSA--TASSGDVLYIAGQPR-YNHTGQVIIYRMEDGNIKILQTLSGEQI 486
Query: 318 ASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQ----------- 365
SYFG + +D++ D D+L VGAP++M E E E G++Y+Y
Sbjct: 487 GSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKE----EQGKVYVYALNQTRFEYQMSL 542
Query: 366 -------VSSLLFRDPQILTGTETFG-RFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRG 417
SS E G RFG+A+A + DLN DG+NDI IG P D G
Sbjct: 543 EPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLED-DHGG 601
Query: 418 KVLIYNGNKDGLNTKPSQVLQGVWASHAVPSG--------FGFTLRGDSDIDKNDYPDLI 469
V IY+G+ + + +Q +PSG FG ++ G+ D++ + D+
Sbjct: 602 AVYIYHGSGKTIRKEYAQ---------RIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVT 652
Query: 470 VGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTG 529
+G G G A++ +R V V + P +N++ K C + T C + VC V
Sbjct: 653 IG--GLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKET--VCINATVCFDVKL 708
Query: 530 QSIANTIV---LMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVY 586
+S +TI L V LDSL+Q I R+ F + + +++ +C Y
Sbjct: 709 KSKEDTIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS---ECTKHSFY 762
Query: 587 LRDETEFRDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNL 646
+ D+ +F+D + I+L+++L + E P+L+ N V E DCG
Sbjct: 763 MLDKHDFQDS---VRITLDFNLTDP------ENGPVLDDSLPNSVHEYIPFAKDCGNKEK 813
Query: 647 CVPDLKLS-ARPDKHQVIIGDENHLMLI-INARNEGEGAYEAELFVMIPEEADYVGIERN 704
C+ DL L A +K +I+ +N + + +N + AY V + GIE
Sbjct: 814 CISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAI 873
Query: 705 NKGFRPLSCEYKMENVTRMVVCDLGNPMVSG---TNYSLGLRFAVPRLEKTNMSINFDLQ 761
K SCE N+T C +G P + + + +F L + ++ L
Sbjct: 874 QKD----SCESN-HNIT----CKVGYPFLRRGEMVTFKILFQFNTSYLME---NVTIYLS 921
Query: 762 IRSSNKDNPDS---NFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVG 818
S +++ P++ N V++ I + ++ + I + + PE + E++G
Sbjct: 922 ATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVI-NSTEDIG 980
Query: 819 PLVEHIYELHNIGPSTISDTILEVGWPFSARDEF-LLYIFHIQTLGPLQCQPNPNINPQD 877
+ Y + G + + L + +P + + +LY + + C+P+ +P
Sbjct: 981 NEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFS 1040
Query: 878 IKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVG 937
I S ++ HL R IL+C + I+C
Sbjct: 1041 IN-----------SGKKMTTSTDHLKR--------------GTILDCNTCKFATITC--- 1072
Query: 938 RLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKT 997
L + + + V LW TF++ + S ++ ++ ++ + + S +
Sbjct: 1073 NLTSSDISQVNVSLILWKPTFIK------SYFSSLNLTIRGELRSENASLVLSSSNQKRE 1126
Query: 998 SVIWATPN-VSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
I + + + +PLWVI+L+ GLL+L +L LALWK GFF R
Sbjct: 1127 LAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKR 1171
Score = 56.2 bits (134), Expect = 2e-07
Identities = 48/154 (31%), Positives = 63/154 (40%), Gaps = 24/154 (15%)
Query: 9 PRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD- 67
PR P +A CC + + C +FN+DV+ +SGP FGY V + +
Sbjct: 3 PRPRARPGVAVACCWLLTVVLR----CCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEE 58
Query: 68 ---ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGT 124
S LVG PK T G VY CP S C + D N I
Sbjct: 59 GKWVLIGSPLVGQPKNRT--------GDVYKCPVGRGESLPC--VKLDLPVNTSI----- 103
Query: 125 KEPIEFKSNQWFGATVKAH-KGKVVACAPLYHWR 157
E K N FG+T+ + G +AC PLY +R
Sbjct: 104 PNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYR 137
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 173 bits (438), Expect = 9e-43
Identities = 211/883 (23%), Positives = 369/883 (41%), Gaps = 102/883 (11%)
Query: 191 NADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLA 250
N G Q GFS K+G ++ G G++ W G V+ + ++A
Sbjct: 364 NESSFGLEMSQIGFSTHRLKDG-ILFGMVGAYDWGGSVLWLEGGHRL-------FPPRMA 415
Query: 251 GEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTD--MTF 308
E + A ++ +YLGYSV++ G ++ ++G PR ++ D +
Sbjct: 416 LEDEFPPALQNHA-AYLGYSVSSMLLRG-GRRLFLSGAPRFRHRGKVIAFQLKKDGAVRV 473
Query: 309 IQNFTGEQMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQ-V 366
Q+ GEQ+ SYFG + D + DG DVL V AP+F+ + +E G++Y+YL
Sbjct: 474 AQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQ----NKETGRVYVYLVGQ 529
Query: 367 SSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK 426
SLL + RFG AM L DLNQDG+ D+A+G P Q G + +Y+G +
Sbjct: 530 QSLLTLQGTLQPEPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQ-GALYLYHGTQ 588
Query: 427 DGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPV 486
G+ P+Q + HA+ S FG ++ G D+D +D D+ VGA G + +RP+
Sbjct: 589 SGVRPHPAQRIAAASMPHAL-SYFGRSVDGRLDLDGDDLVDVAVGA--QGAAILLSSRPI 645
Query: 487 VTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDS 546
V + L + P I++ + C+ A C + +C VT ++ S
Sbjct: 646 VHLTPSLEVTPQAISVVQRDCRRRGQ--EAVCLTAALCFQVTSRTPGRWDHQFYMRFTAS 703
Query: 547 LKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSH-QCQDFIVYLRDETEFRDKLSPINISLN 605
L + A R F + R+ P ++ + C+ ++ D +++ L P+ +++
Sbjct: 704 LDEWTAGARAAF--DGSGQRLSPRRLRLSVGNVTCEQLHFHVLDTSDY---LRPVALTVT 758
Query: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQ---- 661
++LD +T K G P+LN + + DCG DN CV DL L D
Sbjct: 759 FALDNTT-KPG----PVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKA 813
Query: 662 --VIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMEN 719
V+ G +++ N E AY L ++ + + + C +
Sbjct: 814 PFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAH 873
Query: 720 VTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQ 778
+C +G+P+ +G + L F E + S+ + ++ + + +LQ
Sbjct: 874 AR---LCSVGHPVFQTGAKVTFLLEF-----EFSCSSLLSQVFVKLTASSDSLERNGTLQ 925
Query: 779 INITAVAQVEIRGVSHPPQIVL----PIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPST 834
N + + + P ++ +H +E GP + + N+G
Sbjct: 926 DNTAQTSAY----IQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYV 981
Query: 835 ISDTILEVGWPFSAR-DEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAF 893
+S I+ P A + L + + T N + Q++ P PE
Sbjct: 982 VSGLIISALLPAVAHGGNYFLSLSQVIT-------NNASCIVQNLTEPPGPPVHPE---- 1030
Query: 894 LRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRL-EGGESAVLKVRSR 952
+ H R LN +N +C + C +G+L +G E +V +R
Sbjct: 1031 ----ELQHTNR-----------------LNGSNTQCQVVRCHLGQLAKGTEVSVGLLR-- 1067
Query: 953 LWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPA--KLPEGSIAIKTSVIWATPNVSFSI 1010
H R+ +L + +FE+ T++ + +L E S S++ I
Sbjct: 1068 -LVHNEFFRRAKFKSLTVVSTFELG----TEEGSVLQLTEAS-RWSESLLEVVQTRPILI 1121
Query: 1011 PLWVIILAILLGLLVLAILTLALWKCGFFDRARPPQEDMTDRE 1053
LW++I ++L GLL+LA+L LWK GFF + P+E+ + +
Sbjct: 1122 SLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREEK 1164
Score = 37.7 bits (86), Expect = 0.058
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 27 LGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAPKANTSQPD 86
L ++ + C FNLD ++ GP + FGY+V H+ + +LVGAP P
Sbjct: 11 LPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQ-RWMLVGAP---WDGPS 66
Query: 87 IVEGGAVYYCPWPAEGSAQC 106
G VY CP +A C
Sbjct: 67 GDRRGDVYRCPVGGAHNAPC 86
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 167 bits (422), Expect = 6e-41
Identities = 210/907 (23%), Positives = 372/907 (41%), Gaps = 125/907 (13%)
Query: 189 NSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRK 248
N N G Q GFS ++G +++G G++ W G V+ + A + + L++
Sbjct: 356 NKNETSFGLEMSQTGFSSHVVEDG-VLLGAVGAYDWNGAVLKETSAGKVIPLR-ESYLKE 413
Query: 249 LAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII---NSTD 305
E + A YLGY+V + + + VAG PR + G V + N+
Sbjct: 414 FPEELKNHGA-------YLGYTVTS-VVSSRQGRVYVAGAPR-FNHTGKVILFTMHNNRS 464
Query: 306 MTFIQNFTGEQMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYL 364
+T Q G+Q+ SYFG + D++ DG+ DVL VGAP++ + RE G++Y+Y
Sbjct: 465 LTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYF-----NEGRERGKVYVY- 518
Query: 365 QVSSLLFRDPQILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIY 422
++ LF L + ++ RFGS++A + DLNQD YND+ +G P + G + I+
Sbjct: 519 ELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLE-DNHAGAIYIF 577
Query: 423 NGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYR 482
+G + + P Q + + + FG ++ G D++++ DL VGA G +
Sbjct: 578 HGFRGSILKTPKQRITASELATGL-QYFGCSIHGQLDLNEDGLIDLAVGAL--GNAVILW 634
Query: 483 ARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCAS---VTGQSIANTIVLM 539
+RPVV ++A L P IN+ ++ C+ S A C + +C + + T+ +
Sbjct: 635 SRPVVQINASLHFEPSKINIFHRDCK--RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIR 692
Query: 540 AEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSP 599
+D + LD V+ C+ ++ D ++ + P
Sbjct: 693 YNATMDERR----YTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADY---VKP 745
Query: 600 INISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPD- 658
+ S+ YSL++ + P+L+ + C ED CVPDL L AR D
Sbjct: 746 VTFSVEYSLEDP------DHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDL 799
Query: 659 -------------------------KHQVIIGDENHLMLIINA--RNEGEGAYEAELFVM 691
V I + + + A N GE AY L +
Sbjct: 800 PTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNIS 859
Query: 692 IPEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMV---SGTNYSLGLRFA--- 745
+ + + + C + + + VC++ P + + L F+
Sbjct: 860 QSANLQFASLIQKEDSDGSIECVNEERRLQKQ-VCNVSYPFFRAKAKVAFRLDFEFSKSI 918
Query: 746 -VPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHN 804
+ LE ++ D R S K++ N L+ ++ A V S L +
Sbjct: 919 FLHHLE-IELAAGSDSNERDSTKED---NVAPLRFHLKYEADVLFTRSSS-----LSHYE 969
Query: 805 WEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFHIQTLGP 864
+P + + +GP I+ + N+G I ++++ P + R L ++
Sbjct: 970 VKPNSSLERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRL----LKLRDF 1025
Query: 865 LQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNC 924
L + N + N NST R V E R++P LN
Sbjct: 1026 LTDEANTSCN------------------IWGNST-----EYRPTPVEEDLRRAPQ--LNH 1060
Query: 925 TNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQ 984
+N + + I+C + RL + + LW + K ++ +V+ +++ ++
Sbjct: 1061 SNSDVVSINCNI-RLVPNQEINFHLLGNLWLRSLKALKYK--SMKIMVNAALQRQFHSPF 1117
Query: 985 PAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRARP 1044
+ + S I V + + +P+W+I+ + L GLL+LA+L LALWK GFF AR
Sbjct: 1118 IFREEDPSRQI---VFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARR 1174
Query: 1045 PQEDMTD 1051
+E D
Sbjct: 1175 RREPGLD 1181
Score = 36.2 bits (82), Expect = 0.17
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 6/73 (8%)
Query: 26 ALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPDARTASVLVGAP-KANTSQ 84
A + LW FN+D K V G + ++FGY V H + ++VGAP + N Q
Sbjct: 10 AWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQH-DISGNKWLVVGAPLETNGYQ 68
Query: 85 PDIVEGGAVYYCP 97
+ G VY CP
Sbjct: 69 ----KTGDVYKCP 77
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 153 bits (386), Expect = 9e-37
Identities = 204/869 (23%), Positives = 364/869 (41%), Gaps = 112/869 (12%)
Query: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260
Q GFS NG L+ GS+ W G V Y+ K+ K T V +
Sbjct: 352 QEGFSAAITSNGPLL-STVGSYDWAGGVFL---------YTSKE---KSTFINMTRV-DS 397
Query: 261 SYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII--NSTDMTFIQNFTGEQMA 318
+D+YLGY AA + Q LV G PR Q+ G V++ N+ N G Q+
Sbjct: 398 DMNDAYLGY--AAAIILRNRVQSLVLGAPR-YQHIGLVAMFRQNTGMWESNANVKGTQIG 454
Query: 319 SYFGYTVVVSDVNSDGLDD-VLVGAPLFMER----EFESNPREVGQIYLYLQVSSLLFRD 373
+YFG ++ DV+S+G D VL+GAP + E+ + P GQ + Q ++L+ +
Sbjct: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARW-QCDAVLYGE 513
Query: 374 PQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK-DGLNTK 432
+ +GRFG+A+ LGD+N D D+AIG P +D RG V +++G G++
Sbjct: 514 QG-----QPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPS 567
Query: 433 PSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQ 492
SQ + G S + FG +L G D+ + DL VGA G V + R++PV+ V A
Sbjct: 568 HSQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAI 624
Query: 493 LLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGA 552
+ +P + C + +RVC V +T + E Q+ S+
Sbjct: 625 MEFNPREVARNVFECN-DQVVKGKEAGEVRVCLHVQ----KSTRDRLREGQIQSV----- 674
Query: 553 IKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETE---------FRDKLSPINIS 603
+ L LD+ + H + + + S + Q ++ L E D +SPI +
Sbjct: 675 VTYDLALDSGRPHS-RAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLR 733
Query: 604 LNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLS-ARPDKHQV 662
LN+SL + ++P+L + + + +CG DN+C DL ++ + +
Sbjct: 734 LNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCL 793
Query: 663 IIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGI-----ERNNKGFRPLSCE--- 714
++G + + RN+GE +Y ++ P + Y + +R+ + +R L+CE
Sbjct: 794 VVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR-LACESAS 852
Query: 715 -YKMENVTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDS 772
++ + C + +P+ + + + F V + + S N + P +
Sbjct: 853 STEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRT 911
Query: 773 NFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGP 832
N Q+ + V + SH + N+ E + +++H Y++ N+G
Sbjct: 912 NKTEFQLELPVKYAVYMVVTSH--GVSTKYLNFTASENTSR------VMQHQYQVSNLGQ 963
Query: 833 STISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSA 892
++ +++ FL+ + QT+ + +P + + E P S
Sbjct: 964 RSLPISLV-----------FLVPVRLNQTV--IWDRPQVTFSENLSSTCHTKERLPSHSD 1010
Query: 893 FLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSR 952
FL +RK A ++NC+ C +I C + E ++
Sbjct: 1011 FLAE------LRK-------------APVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGN 1051
Query: 953 LWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPL 1012
L +++ ++ + S +T LP +++ PL
Sbjct: 1052 LSFDWYIKTSHNHLLIVSTAEILFNDSVFT----LLPGQGAFVRSQTETKVEPFEVPNPL 1107
Query: 1013 WVIILAILLGLLVLAILTLALWKCGFFDR 1041
+I+ + + GLL+LA++T AL+K GFF R
Sbjct: 1108 PLIVGSSVGGLLLLALITAALYKLGFFKR 1136
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 152 bits (384), Expect = 2e-36
Identities = 204/868 (23%), Positives = 363/868 (41%), Gaps = 111/868 (12%)
Query: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260
Q GFS NG L+ GS+ W G V Y+ K+ K T V +
Sbjct: 352 QEGFSAAITSNGPLL-STVGSYDWAGGVFL---------YTSKE---KSTFINMTRV-DS 397
Query: 261 SYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII--NSTDMTFIQNFTGEQMA 318
+D+YLGY AA + Q LV G PR Q+ G V++ N+ N G Q+
Sbjct: 398 DMNDAYLGY--AAAIILRNRVQSLVLGAPR-YQHIGLVAMFRQNTGMWESNANVKGTQIG 454
Query: 319 SYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFRDPQI 376
+YFG ++ DV+S+G D VL+GAP + E+ GQ+ + L ++ +
Sbjct: 455 AYFGASLCSVDVDSNGSTDLVLIGAPHYYEQT------RGGQVSVCPLPRGRARWQCDAV 508
Query: 377 LTGTE--TFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNK-DGLNTKP 433
L G + +GRFG+A+ LGD+N D D+AIG P +D RG V +++G G++
Sbjct: 509 LYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP-GEEDNRGAVYLFHGTSGSGISPSH 567
Query: 434 SQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQL 493
SQ + G S + FG +L G D+ + DL VGA G V + R++PV+ V A +
Sbjct: 568 SQRIAGSKLSPRL-QYFGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIM 624
Query: 494 LLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQKGAI 553
+P + C + +RVC V +T + E Q+ S+ +
Sbjct: 625 EFNPREVARNVFECN-DQVVKGKEAGEVRVCLHVQ----KSTRDRLREGQIQSV-----V 674
Query: 554 KRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETE---------FRDKLSPINISL 604
L LD+ + H + + + S + Q ++ L E D +SPI + L
Sbjct: 675 TYDLALDSGRPHS-RAVFNETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRL 733
Query: 605 NYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLS-ARPDKHQVI 663
N+SL + ++P+L + + + +CG DN+C DL ++ + ++
Sbjct: 734 NFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLV 793
Query: 664 IGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGI-----ERNNKGFRPLSCE---- 714
+G + + RN+GE +Y ++ P + Y + +R+ + +R L+CE
Sbjct: 794 VGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWR-LACESASS 852
Query: 715 YKMENVTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN 773
++ + C + +P+ + + + F V + + S N + P +N
Sbjct: 853 TEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRTN 911
Query: 774 FVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPS 833
Q+ + V + SH + N+ E + +++H Y++ N+G
Sbjct: 912 KTEFQLELPVKYAVYMVVTSH--GVSTKYLNFTASENTSR------VMQHQYQVSNLGQR 963
Query: 834 TISDTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAF 893
++ +++ FL+ + QT+ + +P + + E P S F
Sbjct: 964 SLPISLV-----------FLVPVRLNQTV--IWDRPQVTFSENLSSTCHTKERLPSHSDF 1010
Query: 894 LRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRL 953
L +RK A ++NC+ C +I C + E ++ L
Sbjct: 1011 LAE------LRK-------------APVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNL 1051
Query: 954 WAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLW 1013
+++ ++ + S +T LP +++ PL
Sbjct: 1052 SFDWYIKTSHNHLLIVSTAEILFNDSVFT----LLPGQGAFVRSQTETKVEPFEVPNPLP 1107
Query: 1014 VIILAILLGLLVLAILTLALWKCGFFDR 1041
+I+ + + GLL+LA++T AL+K GFF R
Sbjct: 1108 LIVGSSVGGLLLLALITAALYKLGFFKR 1135
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 149 bits (376), Expect = 1e-35
Identities = 205/868 (23%), Positives = 364/868 (41%), Gaps = 116/868 (13%)
Query: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVIT--ASVADIIANYSFKDILRKLAGEKQTEVA 258
Q GFS +G L +G GSF W G +++ N S +++ +
Sbjct: 352 QEGFSTALTMDG-LFLGAVGSFSWSGGAFLYPPNMSPTFINMSQENVDMR---------- 400
Query: 259 PASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTDMTFIQN--FTGEQ 316
DSYLGYS + G Q LV G PR Q+ G I + + TG Q
Sbjct: 401 -----DSYLGYSTELALWKG--VQNLVLGAPR-YQHTGKAVIFTQVSRQWRKKAEVTGTQ 452
Query: 317 MASYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFRDP 374
+ SYFG ++ DV+SDG D +L+GAP + E+ GQ+ + L + ++
Sbjct: 453 IGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQT------RGGQVSVCPLPRGRVQWQCD 506
Query: 375 QILTGTE--TFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNG-NKDGLNT 431
+L G + +GRFG+A+ LGD+N+D D+AIG P ++ RG V +++G ++ G++
Sbjct: 507 AVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP-GEQENRGAVYLFHGASESGISP 565
Query: 432 KPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDA 491
SQ + S + FG L G D+ ++ DL VGA G+V + R+ PV+ V
Sbjct: 566 SHSQRIASSQLSPRL-QYFGQALSGGQDLTQDGLMDLAVGA--RGQVLLLRSLPVLKVGV 622
Query: 492 QLLLHPMIINLENKTC--QVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEVQLDSLKQ 549
+ P+ + C + P ++ + VC ++ S+ + + V+ D
Sbjct: 623 AMRFSPVEVAKAVYRCWEEKPSALEAG---DATVCLTIQKSSLDQLGDIQSSVRFDLALD 679
Query: 550 KGAI-KRTLFLDNHQAHRVFPLVIKRQK---SHQCQDFIVYLRDETEFRDKLSPINISLN 605
G + R +F + P + +R+ C+ + L D E D +SPI + LN
Sbjct: 680 PGRLTSRAIFNETKN-----PTLTRRKTLGLGIHCETLKLLLPDCVE--DVVSPIILHLN 732
Query: 606 YSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQVI-I 664
+SL ++P+L +++ + +CG+D LC DL ++ Q + +
Sbjct: 733 FSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTV 792
Query: 665 GDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGI----ERNNKGFRPLSCEY--KME 718
G L +I+ N GE +Y + + P + + ++ ++ L+CE +
Sbjct: 793 GSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTED 852
Query: 719 NVTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDN-PDSNFVS 776
R C + +P+ G+N + + F V K + ++ +S+++N S+ +
Sbjct: 853 EGLRSSRCSVNHPIFHEGSNGTFIVTFDVS--YKATLGDRMLMRASASSENNKASSSKAT 910
Query: 777 LQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTIS 836
Q+ + V +S + + +E+ KE EH Y ++N+
Sbjct: 911 FQLEL-PVKYAVYTMISRQEESTKYFNFATSDEKKMKE------AEHRYRVNNL------ 957
Query: 837 DTILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRN 896
S RD + F + L + D+ A + P +S
Sbjct: 958 ----------SQRDLAISINFWVPVL-------LNGVAVWDVVMEAPSQSLPCVSE---- 996
Query: 897 STIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRL--- 953
RK H + S + +L+C+ +CLQ C V E ++ L
Sbjct: 997 -------RKPPQHSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFG 1049
Query: 954 WAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLW 1013
W LQ+K + S+ Y+ P + E + + ++ V +IP
Sbjct: 1050 WVRETLQKK---VLVVSVAEITFDTSVYSQLPGQ--EAFMRAQMEMVLEEDEVYNAIP-- 1102
Query: 1014 VIILAILLGLLVLAILTLALWKCGFFDR 1041
+I+ + + LL+LA++T L+K GFF R
Sbjct: 1103 IIMGSSVGALLLLALITATLYKLGFFKR 1130
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 142 bits (357), Expect = 2e-33
Identities = 157/634 (24%), Positives = 268/634 (42%), Gaps = 73/634 (11%)
Query: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260
Q GFS +++G G+F W G + R G + A A
Sbjct: 403 QIGFSAQILDERQVLLGAVGAFDWSGGALLYDT-------------RSRRGRFLNQTAAA 449
Query: 261 SYDD-----SYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINS-TDMTFIQNFTG 314
+ D SYLGY+VA T +AG PR + + + +F+ G
Sbjct: 450 AADAEAAQYSYLGYAVAVLHKT--CSLSYIAGAPRYKHHGAVFELQKEGREASFLPVLEG 507
Query: 315 EQMASYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFR 372
EQM SYFG + D++ DG D +LV AP + E G++Y+Y L F
Sbjct: 508 EQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHG------EEGRVYVYRLSEQDGSFS 561
Query: 373 DPQILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAG-----KDQRGKVLIYNGN 425
+IL+G F RFG AMA +GDL+QD D+AIG P G G V IYNG+
Sbjct: 562 LARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGH 621
Query: 426 KDGLNTKPSQVLQGVWASHAVP--SGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRA 483
DGL+ PSQ ++ AS P FG ++ G DI + D+ VG G+ V+R+
Sbjct: 622 WDGLSASPSQRIR---ASTVAPGLQYFGMSMAGGFDISGDGLADITVGTL--GQAVVFRS 676
Query: 484 RPVVTVDAQLLLHPMIINLE-NKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEV 542
RPVV + + P + + N V CF + + +S +L +
Sbjct: 677 RPVVRLKVSMAFTPSALPIGFNGVVNV------RLCFEIS-SVTTASESGLREALLNFTL 729
Query: 543 QLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVY-LRDETEFRDKLSPIN 601
+D KQ+ ++ + R + S C+D ++ E D S +
Sbjct: 730 DVDVGKQRRRLQCSDVRSCLGCLREW-----SSGSQLCEDLLLMPTEGELCEEDCFSNAS 784
Query: 602 ISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQ 661
+ ++Y L ++ + +PIL+ Y E Q C CV +L+L+ + +
Sbjct: 785 VKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVSQQE 843
Query: 662 VIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRP-LSCEYKMENV 720
+++G L L IN N GE +Y + + P + ++R K P + C+
Sbjct: 844 LVVGLTKELTLNINLTNSGEDSYMTSMALNYPRN---LQLKRMQKPPSPNIQCDDPQPVA 900
Query: 721 TRMVV-CDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN------ 773
+ +++ C +G+P++ ++ + + + + N + + + + +SN+ +N
Sbjct: 901 SVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQ 960
Query: 774 ----FVSLQINITAVAQVEIRGVSHPPQIVLPIH 803
FV++ + + +G+SH + + +H
Sbjct: 961 FRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVH 994
Score = 33.5 bits (75), Expect = 1.1
Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Query: 996 KTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
K +V++ S+P +II + GLLVL ++ + L+KCGFF R
Sbjct: 1111 KITVVFLKDEKYHSLP--IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 141 bits (356), Expect = 3e-33
Identities = 158/598 (26%), Positives = 271/598 (45%), Gaps = 75/598 (12%)
Query: 202 AGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPAS 261
+G S D + G +VG G+ W G F D+ L + P +
Sbjct: 269 SGISADLSR-GHAVVGAVGAKDWAG--------------GFLDLKADLQDDTFIGNEPLT 313
Query: 262 YD--DSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTD----MTFIQNFTGE 315
+ YLGY+V + L +G PR Q+ G V + + +Q G
Sbjct: 314 PEVRAGYLGYTVTWLP-SRQKTSLLASGAPR-YQHMGRVLLFQEPQGGGHWSQVQTIHGT 371
Query: 316 QMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDP 374
Q+ SYFG + DV+ DG ++L +GAPLF + G++++Y Q L F +
Sbjct: 372 QIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ------RGGRVFIY-QRRQLGFEEV 424
Query: 375 QILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTK 432
L G + GRFG A+ L D+N DG D+A+G P +++G V I+NG GL+ +
Sbjct: 425 SELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQ 481
Query: 433 PSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQ 492
PSQ ++G + FG ++ G D++ + D+ VGA ++ V +RPVV +
Sbjct: 482 PSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTL 538
Query: 493 LLLHPMIINLENKTC------QVPDSMTSAACFSLR-VCASVTGQSIANTIVLMAEVQLD 545
+ P I + C ++ + + CF ++ + G+ +AN L +QLD
Sbjct: 539 MSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN---LTYTLQLD 595
Query: 546 SLKQKGAIKRTLFL-DNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISL 604
+ + +R LF H+ R + S C DF + +D +SPIN+SL
Sbjct: 596 GHRTR---RRGLFPGGRHELRRNIAVT----TSMSCTDFSFHF--PVCVQDLISPINVSL 646
Query: 605 NYSL--DESTFKE---GLEVKPILNYYRENIVSEQAHILVD--CGEDNLCVPDLKLSARP 657
N+SL +E T ++ G ++ PIL R ++ SE I + CGED C +L++S P
Sbjct: 647 NFSLWEEEGTPRDQRAGKDIPPIL---RPSLHSETWEIPFEKNCGEDKKCEANLRVSFSP 703
Query: 658 DKHQVI-IGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFR-PLSCEY 715
+ + + + L + ++ N E AY +L + P + +E + P+SCE
Sbjct: 704 ARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEE 763
Query: 716 KMEN---VTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDN 769
E ++R + C++ +P+ +G + +L + F S+ + +N+D+
Sbjct: 764 LPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDS 821
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 141 bits (355), Expect = 4e-33
Identities = 158/599 (26%), Positives = 271/599 (45%), Gaps = 76/599 (12%)
Query: 202 AGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPAS 261
+G S D + G +VG G+ W G F D+ L + P +
Sbjct: 352 SGISADLSR-GHAVVGAVGAKDWAG--------------GFLDLKADLQDDTFIGNEPLT 396
Query: 262 YD--DSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINSTD----MTFIQNFTGE 315
+ YLGY+V + L +G PR Q+ G V + + +Q G
Sbjct: 397 PEVRAGYLGYTVTWLP-SRQKTSLLASGAPR-YQHMGRVLLFQEPQGGGHWSQVQTIHGT 454
Query: 316 QMASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQVSSLLFRDP 374
Q+ SYFG + DV+ DG ++L +GAPLF + G++++Y Q L F +
Sbjct: 455 QIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQ------RGGRVFIY-QRRQLGFEEV 507
Query: 375 QILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTK 432
L G + GRFG A+ L D+N DG D+A+G P +++G V I+NG GL+ +
Sbjct: 508 SELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPL---EEQGAVYIFNGRHGGLSPQ 564
Query: 433 PSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQ 492
PSQ ++G + FG ++ G D++ + D+ VGA ++ V +RPVV +
Sbjct: 565 PSQRIEGTQVLSGI-QWFGRSIHGVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTL 621
Query: 493 LLLHPMIINLENKTC------QVPDSMTSAACFSLR-VCASVTGQSIANTIVLMAEVQLD 545
+ P I + C ++ + + CF ++ + G+ +AN L +QLD
Sbjct: 622 MSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVAN---LTYTLQLD 678
Query: 546 SLKQKGAIKRTLFL-DNHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISL 604
+ + +R LF H+ R + S C DF + +D +SPIN+SL
Sbjct: 679 GHRTR---RRGLFPGGRHELRRNIAVT----TSMSCTDFSFHF--PVCVQDLISPINVSL 729
Query: 605 NYSL--DESTFK----EGLEVKPILNYYRENIVSEQAHILVD--CGEDNLCVPDLKLSAR 656
N+SL +E T + +G ++ PIL R ++ SE I + CGED C +L++S
Sbjct: 730 NFSLWEEEGTPRDQRAQGKDIPPIL---RPSLHSETWEIPFEKNCGEDKKCEANLRVSFS 786
Query: 657 PDKHQVI-IGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFR-PLSCE 714
P + + + + L + ++ N E AY +L + P + +E + P+SCE
Sbjct: 787 PARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCE 846
Query: 715 YKMEN---VTRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDN 769
E ++R + C++ +P+ +G + +L + F S+ + +N+D+
Sbjct: 847 ELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDS 905
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 138 bits (347), Expect = 3e-32
Identities = 210/866 (24%), Positives = 351/866 (40%), Gaps = 108/866 (12%)
Query: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVIT--ASVADIIANYSFKDILRKLAGEKQTEVA 258
Q GFS F +G ++G GSF W G +++ N S +++ +
Sbjct: 353 QEGFSAVFTPDGP-VLGAVGSFTWSGGAFLYPPNMSPTFINMSQENVDMR---------- 401
Query: 259 PASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIIN--STDMTFIQNFTGEQ 316
DSYLGYS + G Q LV G PR Q+ G I S TG Q
Sbjct: 402 -----DSYLGYSTELALWKG--VQSLVLGAPR-YQHTGKAVIFTQVSRQWRMKAEVTGTQ 453
Query: 317 MASYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFRDP 374
+ SYFG ++ DV+SDG D VL+GAP + E+ GQ+ + L +
Sbjct: 454 IGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQT------RGGQVSVCPLPRGWRRWWCD 507
Query: 375 QILTGTE--TFGRFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNG-NKDGLNT 431
+L G + +GRFG+A+ LGD+N D D+ IG P ++ RG V +++G ++
Sbjct: 508 AVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAP-GEEENRGAVYLFHGVLGPSISP 566
Query: 432 KPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDA 491
SQ + G S + FG L G D+ ++ DL VGA G+V + R RPV+ V
Sbjct: 567 SHSQRIAGSQLSSRL-QYFGQALSGGQDLTQDGLVDLAVGA--RGQVLLLRTRPVLWVGV 623
Query: 492 QLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTGQS--IANTIVLMAEVQLDSLKQ 549
+ P I C+ ++ +C + +S + + L + V LD
Sbjct: 624 SMQFIPAEIPRSAFECR-EQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALD 682
Query: 550 KGAIK-RTLFLD--NHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNY 606
G + R F + N RV L +K C++F + L E D ++PI + LN+
Sbjct: 683 PGRLSPRATFQETKNRSLSRVRVLGLKA----HCENFNLLLPSCVE--DSVTPITLRLNF 736
Query: 607 SLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLS-ARPDKHQVIIG 665
+L ++P+L + + +CG D++C +L +S + P +++G
Sbjct: 737 TLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVG 796
Query: 666 DENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRPLSCEYKMENV----- 720
L + N+GE +Y + P Y + K + S ++
Sbjct: 797 SNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQ 856
Query: 721 -TRMVVCDLGNPMV-SGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFVSLQ 778
T C + + + G + F V + + S N + P ++ + Q
Sbjct: 857 GTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSEN-NTPRTSKTTFQ 915
Query: 779 INITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDT 838
+ + V VS Q ++ E EE KE V H Y+++N+G + +
Sbjct: 916 LEL-PVKYAVYTVVSSHEQFTKYLNFSESEE---KESHV---AMHRYQVNNLGQRDLPVS 968
Query: 839 ILEVGWPFSARDEFLLYIFHIQTLGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNST 898
I P E + ++ P NP++ +S + P S FL
Sbjct: 969 I-NFWVPVELNQEAVW--MDVEVSHP----QNPSLR------CSSEKIAPPASDFL---- 1011
Query: 899 IPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVGRLEGGESAVLKVRSRL---WA 955
H+ +++P +L+C+ CL+ C V E ++ L W
Sbjct: 1012 ---------AHI----QKNP--VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWV 1056
Query: 956 HTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVI 1015
LQ+K ++ S+ Y+ P + E + +T+ + V PL I
Sbjct: 1057 RQILQKK---VSVVSVAEITFDTSVYSQLPGQ--EAFMRAQTTTVLEKYKVHNPTPL--I 1109
Query: 1016 ILAILLGLLVLAILTLALWKCGFFDR 1041
+ + + GLL+LA++T L+K GFF R
Sbjct: 1110 VGSSIGGLLLLALITAVLYKVGFFKR 1135
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 47.8 bits (112), Expect = 6e-05
Identities = 53/217 (24%), Positives = 86/217 (39%), Gaps = 26/217 (11%)
Query: 261 SYDDSYLGYSVAAGEFTGDSQQELVAGIPR----GAQNFGYVSIINSTDMTFI------- 309
S+ + LG+++ + + D +LV G P G + G V +I D+
Sbjct: 375 SFPYARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLD 434
Query: 310 ----QNFTGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYL- 364
+ G Q + FG + V D N DG+ D+ VGAP + G +Y+Y
Sbjct: 435 KEAHRILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYK----GAVYVYFG 490
Query: 365 QVSSLLFRDPQI-LTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFA--GKDQRGKVLI 421
+ P I ++ + + G + D+N D D+ IG PFA G Q+G V
Sbjct: 491 SKQGGMSSSPNITISCQDIYCNLGWTLL-AADVNGDSEPDLVIGSPFAPGGGKQKGIVAA 549
Query: 422 YNGNKDGLNTKPSQVLQGVWASHAVP--SGFGFTLRG 456
+ + + V W S FG++L G
Sbjct: 550 FYSGPSLSDKEKLNVEAANWTVRGEEDFSWFGYSLHG 586
Score = 42.0 bits (97), Expect = 0.003
Identities = 70/301 (23%), Positives = 110/301 (36%), Gaps = 51/301 (16%)
Query: 199 YCQAGFSL-----DFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEK 253
YC G++L + DL++G P F G VA + S D KL E
Sbjct: 510 YCNLGWTLLAADVNGDSEPDLVIGSP--FAPGGGKQKGIVAAFYSGPSLSD-KEKLNVEA 566
Query: 254 QTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIP--RGAQNFGYVSIINSTDMTFIQN 311
D S+ GYS+ T D++ L+ G P + A G++ I + +
Sbjct: 567 ANWTVRGEEDFSWFGYSLHG--VTVDNRTLLLVGSPTWKNASRLGHLLHIRDEKKSLGRV 624
Query: 312 F-------------TGEQMASYFGYTVVVSDVNSDGL--DDVLVGAPLFMERE----FES 352
+ +G++ G ++ V +G +LVGAP + +
Sbjct: 625 YGYFPPNGQSWFTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLTV 684
Query: 353 NPREVGQIYLYLQVSSLLFRDPQILTGTETFGRFGSAMAHLGDLNQDGYNDIAIGVPFAG 412
+ G +Y S +G F RFG + HL DL+ DG ++I + P
Sbjct: 685 TLHQGGATRMYALTSDAQPLLLSTFSGDRRFSRFGGVL-HLSDLDDDGLDEIIMAAPLRI 743
Query: 413 KD--------QRGKVLIYNGN-----------KDGLNTKPSQVLQGVWASHAVPSGFGFT 453
D + G+V +YNG K + P + Q V S S FG +
Sbjct: 744 ADVTSGLIGGEDGRVYVYNGKETTLGDMTGKCKSWITPCPEEKAQYVLISPEASSRFGSS 803
Query: 454 L 454
L
Sbjct: 804 L 804
Score = 35.4 bits (80), Expect = 0.29
Identities = 35/155 (22%), Positives = 61/155 (39%), Gaps = 10/155 (6%)
Query: 198 GYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEV 257
G+ L+ +GDL+VG PG + G + V I N + ++ +
Sbjct: 382 GWAMTSADLNQDGHGDLVVGAPG-YSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHRI 440
Query: 258 APASYDDSYLGYSVAAGEFTGDSQQELVAGIPR-GAQNFGYVSII------NSTDMTFIQ 310
G ++A +F D +L G P G++ Y + M+
Sbjct: 441 LEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSSP 500
Query: 311 NFTGEQMASY--FGYTVVVSDVNSDGLDDVLVGAP 343
N T Y G+T++ +DVN D D+++G+P
Sbjct: 501 NITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSP 535
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 42.0 bits (97), Expect = 0.003
Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 10/124 (8%)
Query: 921 ILNCTNIECLQISCAVGRLEGGESAVLKVRSRL---WAHTFLQRKNDPYALASLVSFEVK 977
+L+C+ CL+ C V E ++ L W LQ+K ++A ++F+
Sbjct: 318 VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAE-ITFDTS 376
Query: 978 KMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCG 1037
Y+ P + E + +T+ + V PL I+ + + GLL+LA++T L+K G
Sbjct: 377 V--YSQLPGQ--EAFMRAQTTTVLEKYKVHNPTPL--IVGSSIGGLLLLALITAVLYKVG 430
Query: 1038 FFDR 1041
FF R
Sbjct: 431 FFKR 434
>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
sapiens]
Length = 592
Score = 32.7 bits (73), Expect = 1.9
Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 4/64 (6%)
Query: 785 AQVEIRGVSHPPQIVLPIHNWEPEEEPH---KEEEVGPLVEH-IYELHNIGPSTISDTIL 840
A+++ GVS PP+ P E +++PH ++E G L++ ++ + P+ + +L
Sbjct: 45 ARLQEAGVSIPPRRGRPTPTLEKKKKPHLMAEDEPSGALLKPLVFRVDETTPAVVQSVLL 104
Query: 841 EVGW 844
E GW
Sbjct: 105 ERGW 108
>gi|238550202 tubby like protein 3 isoform 2 [Homo sapiens]
Length = 501
Score = 30.8 bits (68), Expect = 7.1
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 862 LGPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKI 921
L P QPNP + KP AS E TP L N PH +V+ PA +
Sbjct: 44 LEPFMVQPNPEARLRRAKPRASDEQTP-----LVNCHTPH------SNVILHGIDGPAAV 92
Query: 922 LNCTNIECLQISCAV 936
L + +S +V
Sbjct: 93 LKPDEVHAPSVSSSV 107
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,727,906
Number of Sequences: 37866
Number of extensions: 2030787
Number of successful extensions: 4591
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4210
Number of HSP's gapped (non-prelim): 67
length of query: 1063
length of database: 18,247,518
effective HSP length: 113
effective length of query: 950
effective length of database: 13,968,660
effective search space: 13270227000
effective search space used: 13270227000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.