Guide to the Human Genome
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Search of human proteins with 4885069

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885069 ras homolog gene family, member E [Homo sapiens]
         (244 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885069 ras homolog gene family, member E [Homo sapiens]           493   e-140
gi|4885581 Rho family GTPase 2 [Homo sapiens]                         308   4e-84
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                    301   4e-82
gi|10835049 ras homolog gene family, member A [Homo sapiens]          198   3e-51
gi|111494251 ras homolog gene family, member C precursor [Homo s...   197   7e-51
gi|111494248 ras homolog gene family, member C precursor [Homo s...   197   7e-51
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   197   7e-51
gi|4757764 ras homolog gene family, member B [Homo sapiens]           192   2e-49
gi|7656900 ras homolog D [Homo sapiens]                               171   4e-43
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   170   9e-43
gi|38016957 ras homolog gene family, member F [Homo sapiens]          169   2e-42
gi|46249393 ras homolog gene family, member G [Homo sapiens]          166   1e-41
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   164   5e-41
gi|50263042 ras-like protein TC10 [Homo sapiens]                      164   7e-41
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   162   3e-40
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   159   3e-39
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           154   7e-38
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           152   3e-37
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            152   3e-37
gi|16903164 ras homolog gene family, member J [Homo sapiens]          148   5e-36
gi|11034843 ras homolog gene family, member U [Homo sapiens]          147   1e-35
gi|229577148 ras homolog gene family, member V [Homo sapiens]         130   8e-31
gi|4757770 ras homolog gene family, member H [Homo sapiens]           128   4e-30
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]         87   1e-17
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...    85   7e-17
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...    84   9e-17
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...    84   9e-17
gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]          79   4e-15
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap...    79   5e-15
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]           78   8e-15

>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score =  493 bits (1269), Expect = e-140
 Identities = 244/244 (100%), Positives = 244/244 (100%)

Query: 1   MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY 60
           MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY
Sbjct: 1   MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY 60

Query: 61  TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120
           TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE
Sbjct: 61  TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120

Query: 121 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 180
           IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL
Sbjct: 121 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 180

Query: 181 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS 240
           QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS
Sbjct: 181 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS 240

Query: 241 CTVM 244
           CTVM
Sbjct: 241 CTVM 244


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score =  308 bits (788), Expect = 4e-84
 Identities = 144/225 (64%), Positives = 185/225 (82%), Gaps = 1/225 (0%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q+ +CKIVVVGD++CGKTALL VFAKD +P +YVPTVFENYTASFEID +RIEL++WDTS
Sbjct: 4   QSGRCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTS 63

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           GS YYDNVRPL+YPDSDAVLICFDISRPETLDSVLKKW+GE QEFCPN K++LVGCK D+
Sbjct: 64  GSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDM 123

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVN 199
           RTD++TL ELS  R  PV+++QG  +AKQ+GA +Y+ECS+  SE SVRD+FHVAT+A + 
Sbjct: 124 RTDLATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLG 183

Query: 200 KTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKSCTVM 244
           + ++ ++R  S+R  +R + +  RP+      ++ KD+AKSC +M
Sbjct: 184 RGHRQLRRTDSRRGMQRSAQLSGRPDRGNEG-EIHKDRAKSCNLM 227


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score =  301 bits (770), Expect = 4e-82
 Identities = 142/244 (58%), Positives = 189/244 (77%), Gaps = 12/244 (4%)

Query: 1   MKERRASQKLSSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY 60
           MKERRA Q + ++          CK+V+VGD QCGKTA+L V AKDC+PE YVPTVFENY
Sbjct: 1   MKERRAPQPVVAR----------CKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENY 50

Query: 61  TASFEIDTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120
           TA  E + QR+ELSLWDTSGSPYYDNVRPL Y DSDAVL+CFDISRPET+DS LKKW+ E
Sbjct: 51  TACLETEEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTE 110

Query: 121 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 180
           I ++CP+T++LL+GCK+DLRTD+STL+ELS+ +Q P+SY+QG  +AKQ+GA  Y+E SA 
Sbjct: 111 ILDYCPSTRVLLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAF 170

Query: 181 QSENSVRDIFHVATLACVNKTNKNVKRNKSQRATKRISHMPSRPELSAVATDLRKDKAKS 240
            SE S+  IF  A++ C+NK +   +++  +  +KR+ H+PSR EL  +++  +K+KAKS
Sbjct: 171 TSEKSIHSIFRTASMLCLNKPSPLPQKSPVRSLSKRLLHLPSRSEL--ISSTFKKEKAKS 228

Query: 241 CTVM 244
           C++M
Sbjct: 229 CSIM 232


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  198 bits (504), Expect = 3e-51
 Identities = 91/177 (51%), Positives = 131/177 (74%), Gaps = 1/177 (0%)

Query: 22  VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGS 81
           ++ K+V+VGD  CGKT LL VF+KD FPE YVPTVFENY A  E+D +++EL+LWDT+G 
Sbjct: 4   IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQ 63

Query: 82  PYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRT 141
             YD +RPLSYPD+D +L+CF I  P++L+++ +KW  E++ FCPN  ++LVG K DLR 
Sbjct: 64  EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRN 123

Query: 142 DVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV 198
           D  T  EL+  +Q PV  ++G +MA +IGA  Y+ECSA ++++ VR++F +AT A +
Sbjct: 124 DEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSA-KTKDGVREVFEMATRAAL 179


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  197 bits (501), Expect = 7e-51
 Identities = 93/191 (48%), Positives = 135/191 (70%), Gaps = 6/191 (3%)

Query: 22  VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGS 81
           ++ K+V+VGD  CGKT LL VF+KD FPE YVPTVFENY A  E+D +++EL+LWDT+G 
Sbjct: 4   IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQ 63

Query: 82  PYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRT 141
             YD +RPLSYPD+D +L+CF I  P++L+++ +KW  E++ FCPN  ++LVG K DLR 
Sbjct: 64  EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQ 123

Query: 142 DVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKT 201
           D  T  EL+  +Q PV  ++G +MA +I A  Y+ECSA +++  VR++F +AT     + 
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSA-KTKEGVREVFEMAT-----RA 177

Query: 202 NKNVKRNKSQR 212
              V++NK +R
Sbjct: 178 GLQVRKNKRRR 188


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  197 bits (501), Expect = 7e-51
 Identities = 93/191 (48%), Positives = 135/191 (70%), Gaps = 6/191 (3%)

Query: 22  VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGS 81
           ++ K+V+VGD  CGKT LL VF+KD FPE YVPTVFENY A  E+D +++EL+LWDT+G 
Sbjct: 4   IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQ 63

Query: 82  PYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRT 141
             YD +RPLSYPD+D +L+CF I  P++L+++ +KW  E++ FCPN  ++LVG K DLR 
Sbjct: 64  EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQ 123

Query: 142 DVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKT 201
           D  T  EL+  +Q PV  ++G +MA +I A  Y+ECSA +++  VR++F +AT     + 
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSA-KTKEGVREVFEMAT-----RA 177

Query: 202 NKNVKRNKSQR 212
              V++NK +R
Sbjct: 178 GLQVRKNKRRR 188


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  197 bits (501), Expect = 7e-51
 Identities = 93/191 (48%), Positives = 135/191 (70%), Gaps = 6/191 (3%)

Query: 22  VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGS 81
           ++ K+V+VGD  CGKT LL VF+KD FPE YVPTVFENY A  E+D +++EL+LWDT+G 
Sbjct: 4   IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQ 63

Query: 82  PYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRT 141
             YD +RPLSYPD+D +L+CF I  P++L+++ +KW  E++ FCPN  ++LVG K DLR 
Sbjct: 64  EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQ 123

Query: 142 DVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKT 201
           D  T  EL+  +Q PV  ++G +MA +I A  Y+ECSA +++  VR++F +AT     + 
Sbjct: 124 DEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSA-KTKEGVREVFEMAT-----RA 177

Query: 202 NKNVKRNKSQR 212
              V++NK +R
Sbjct: 178 GLQVRKNKRRR 188


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  192 bits (489), Expect = 2e-49
 Identities = 90/179 (50%), Positives = 126/179 (70%), Gaps = 1/179 (0%)

Query: 22  VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGS 81
           ++ K+VVVGD  CGKT LL VF+KD FPE YVPTVFENY A  E+D +++EL+LWDT+G 
Sbjct: 4   IRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQ 63

Query: 82  PYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRT 141
             YD +RPLSYPD+D +L+CF +  P++L+++ +KW  E++ FCPN  ++LV  K DLR+
Sbjct: 64  EDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRS 123

Query: 142 DVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNK 200
           D     EL+  +Q PV  D G  MA +I A  Y+ECSA +++  VR++F  AT A + K
Sbjct: 124 DEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSA-KTKEGVREVFETATRAALQK 181


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  171 bits (434), Expect = 4e-43
 Identities = 77/187 (41%), Positives = 117/187 (62%), Gaps = 1/187 (0%)

Query: 25  KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYY 84
           K+V+VGD  CGKT+LL VFA   FPE+Y PTVFE Y  + ++  + + L +WDT+G   Y
Sbjct: 19  KVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDY 78

Query: 85  DNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVS 144
           D +RPL YPD+  +L+CFD++ P + D++  +W  E+  FC    +++VGCK+DLR D S
Sbjct: 79  DRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLRKDKS 138

Query: 145 TLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKN 204
            + +L  +   PV+Y +G  MA+ +GA  Y+ECSA   +N V  +F  A    ++   +N
Sbjct: 139 LVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDN-VHAVFQEAAEVALSSRGRN 197

Query: 205 VKRNKSQ 211
             R  +Q
Sbjct: 198 FWRRITQ 204


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  170 bits (431), Expect = 9e-43
 Identities = 82/177 (46%), Positives = 115/177 (64%), Gaps = 3/177 (1%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q +KC  VVVGD   GKT LL  +  + FP  Y+PTVF+NY+A+  +D + + L LWDT+
Sbjct: 2   QAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTA 59

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   YD +RPLSYP +D  LICF +  P + ++V  KW  E++  CPNT ++LVG K DL
Sbjct: 60  GQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDL 119

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLA 196
           R D  T+ +L   + TP++Y QG  MAK+IGA  Y+ECSAL ++  ++ +F  A  A
Sbjct: 120 RDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL-TQRGLKTVFDEAIRA 175


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score =  169 bits (429), Expect = 2e-42
 Identities = 85/188 (45%), Positives = 122/188 (64%), Gaps = 2/188 (1%)

Query: 25  KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYY 84
           KIV+VGD  CGKT+LL V+++  FPE+Y P+VFE YTAS  + ++ + L+L+DT+G   Y
Sbjct: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80

Query: 85  DNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVS 144
           D +RPLSY ++  VLIC+D+  P + D+VL KW  E+  FC    M+L+GCK+DLR D  
Sbjct: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140

Query: 145 TLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKN 204
            L +L   +  P++Y QG +  +QI AA Y+ECSA   EN V D+F  A    ++   K 
Sbjct: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN-VEDVFREAAKVALSAL-KK 198

Query: 205 VKRNKSQR 212
            +R K +R
Sbjct: 199 AQRQKKRR 206


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  166 bits (421), Expect = 1e-41
 Identities = 84/191 (43%), Positives = 120/191 (62%), Gaps = 5/191 (2%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q++KC  VVVGD   GKT LL  +  + FP+ Y+PTVF+NY+A   +D + + L+LWDT+
Sbjct: 2   QSIKC--VVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTA 59

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   YD +R LSYP ++  +ICF I+ P + ++V  KW  E+   CP+  +LLVG K DL
Sbjct: 60  GQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDL 119

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVN 199
           R    TL  L    Q P++  QG  +AKQI A  Y+ECSALQ ++ V+++F  A  A +N
Sbjct: 120 RAQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQ-QDGVKEVFAEAVRAVLN 178

Query: 200 KTNKNVKRNKS 210
            T   +KR +S
Sbjct: 179 PT--PIKRGRS 187


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  164 bits (416), Expect = 5e-41
 Identities = 79/177 (44%), Positives = 114/177 (64%), Gaps = 3/177 (1%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q +KC  VVVGD   GKT LL  +  + FP  Y+PTVF+NY+A+  +D + + L LWDT+
Sbjct: 2   QAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTA 59

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   YD +RPLSYP +D  LICF +  P + ++V  KW  E++  CP+T +LLVG K DL
Sbjct: 60  GQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDL 119

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLA 196
           R D  T+  L + +  P++Y QG  MA++IG+  Y+ECSAL ++  ++ +F  A  A
Sbjct: 120 RDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSAL-TQRGLKTVFDEAIRA 175


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  164 bits (415), Expect = 7e-41
 Identities = 79/188 (42%), Positives = 116/188 (61%), Gaps = 1/188 (0%)

Query: 25  KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYY 84
           K VVVGD   GKT LL  +A D FPE YVPTVF++Y  S  +  ++  L L+DT+G   Y
Sbjct: 11  KCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDY 70

Query: 85  DNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVS 144
           D +RPLSYP +D  LICF +  P +  +V ++W  E++E+ PN   LL+G + DLR D  
Sbjct: 71  DRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPK 130

Query: 145 TLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKN 204
           TL  L++ ++ P+  +QG  +AK+IGA  Y+ECSAL ++  ++ +F  A +A +      
Sbjct: 131 TLARLNDMKEKPICVEQGQKLAKEIGACCYVECSAL-TQKGLKTVFDEAIIAILTPKKHT 189

Query: 205 VKRNKSQR 212
           VK+    R
Sbjct: 190 VKKRIGSR 197


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  162 bits (409), Expect = 3e-40
 Identities = 77/177 (43%), Positives = 114/177 (64%), Gaps = 3/177 (1%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q +KC  VVVGD   GKT LL  +  + FP  Y+PTVF+NY+A+  +D++ + L LWDT+
Sbjct: 2   QAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTA 59

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   YD +RPLSYP +D  LICF +  P + ++V  KW  E++  CP+T ++LVG K DL
Sbjct: 60  GQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDL 119

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLA 196
           R D  T+ +L   +  P++Y QG  +AK+I +  Y+ECSAL ++  ++ +F  A  A
Sbjct: 120 RDDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSAL-TQRGLKTVFDEAIRA 175


>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  159 bits (401), Expect = 3e-39
 Identities = 82/196 (41%), Positives = 115/196 (58%), Gaps = 22/196 (11%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q +KC  VVVGD   GKT LL  +  + FP  Y+PTVF+NY+A+  +D + + L LWDT+
Sbjct: 2   QAIKC--VVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTA 59

Query: 80  GSPYYDNVRPLSYPDS-------------------DAVLICFDISRPETLDSVLKKWKGE 120
           G   YD +RPLSYP +                   D  LICF +  P + ++V  KW  E
Sbjct: 60  GQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPE 119

Query: 121 IQEFCPNTKMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSAL 180
           ++  CPNT ++LVG K DLR D  T+ +L   + TP++Y QG  MAK+IGA  Y+ECSAL
Sbjct: 120 VRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSAL 179

Query: 181 QSENSVRDIFHVATLA 196
            ++  ++ +F  A  A
Sbjct: 180 -TQRGLKTVFDEAIRA 194


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  154 bits (389), Expect = 7e-38
 Identities = 77/188 (40%), Positives = 113/188 (60%), Gaps = 3/188 (1%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q +KC  VVVGD   GKT LL  +  + FP  YVPTVF+NY  +  I  +   L L+DT+
Sbjct: 2   QTIKC--VVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTA 59

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   YD +RPLSYP +D  L+CF +  P + ++V +KW  EI   CP T  LLVG + DL
Sbjct: 60  GQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDL 119

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVN 199
           R D ST+ +L+ ++Q P++ +    +A+ + A  Y+ECSAL ++  ++++F  A LA + 
Sbjct: 120 RDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSAL-TQRGLKNVFDEAILAALE 178

Query: 200 KTNKNVKR 207
                 KR
Sbjct: 179 PPETQPKR 186


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  152 bits (384), Expect = 3e-37
 Identities = 75/179 (41%), Positives = 111/179 (62%), Gaps = 3/179 (1%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q +KC  VVVGD   GKT LL  +  + FP  YVPTVF+NY  +  I  +   L L+DT+
Sbjct: 2   QTIKC--VVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTA 59

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   YD +RPLSYP +D  L+CF +  P + ++V +KW  EI   CP T  LLVG + DL
Sbjct: 60  GQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDL 119

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV 198
           R D ST+ +L+ ++Q P++ +    +A+ + A  Y+ECSAL ++  ++++F  A LA +
Sbjct: 120 RDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSAL-TQKGLKNVFDEAILAAL 177


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  152 bits (384), Expect = 3e-37
 Identities = 75/179 (41%), Positives = 111/179 (62%), Gaps = 3/179 (1%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           Q +KC  VVVGD   GKT LL  +  + FP  YVPTVF+NY  +  I  +   L L+DT+
Sbjct: 2   QTIKC--VVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTA 59

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   YD +RPLSYP +D  L+CF +  P + ++V +KW  EI   CP T  LLVG + DL
Sbjct: 60  GQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDL 119

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV 198
           R D ST+ +L+ ++Q P++ +    +A+ + A  Y+ECSAL ++  ++++F  A LA +
Sbjct: 120 RDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSAL-TQKGLKNVFDEAILAAL 177


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  148 bits (373), Expect = 5e-36
 Identities = 74/187 (39%), Positives = 114/187 (60%), Gaps = 3/187 (1%)

Query: 17  DPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLW 76
           D  + +KC  VVVGD   GKT LL  +A D FPE YVPTVF++Y  +  +  ++  L L+
Sbjct: 17  DEKKMLKC--VVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLY 74

Query: 77  DTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCK 136
           DT+G   Y+ +RPLSYP++D  LICF +  P +  +V ++W  E+++  P+   +L+G +
Sbjct: 75  DTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQ 134

Query: 137 SDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLA 196
            DLR D  TL  L   ++ P++Y+ G  +AK IGA  Y+ECSAL ++  ++ +F  A L 
Sbjct: 135 IDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSAL-TQKGLKAVFDEAILT 193

Query: 197 CVNKTNK 203
             +   K
Sbjct: 194 IFHPKKK 200


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  147 bits (370), Expect = 1e-35
 Identities = 75/198 (37%), Positives = 122/198 (61%), Gaps = 5/198 (2%)

Query: 20  QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTS 79
           + VKC  V+VGD   GKT+L+  +  + +P  Y+PT F+N++A   +D + + L L DT+
Sbjct: 48  RGVKC--VLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTA 105

Query: 80  GSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDL 139
           G   +D +RPL Y ++D  L+CF +  P +  +V +KW  EI+  CP   ++LVG +SDL
Sbjct: 106 GQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDL 165

Query: 140 RTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV- 198
           R DV  L+EL   ++ PV  +     A++I AA+YIECSAL  +N ++++F  A +A + 
Sbjct: 166 REDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKN-LKEVFDAAIVAGIQ 224

Query: 199 -NKTNKNVKRNKSQRATK 215
            + T +  K++KS+   K
Sbjct: 225 YSDTQQQPKKSKSRTPDK 242


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  130 bits (328), Expect = 8e-31
 Identities = 64/182 (35%), Positives = 107/182 (58%), Gaps = 4/182 (2%)

Query: 18  PNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWD 77
           P   +KC  V+VGD   GK++L+  +  + +P  Y PT  + ++    +D   + + LWD
Sbjct: 28  PELGIKC--VLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWD 85

Query: 78  TSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKS 137
           T+G   +D +R L YPD+D  L CF + +P +  ++ +KW  EI+   P   +LLVG ++
Sbjct: 86  TAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQA 145

Query: 138 DLRTDVSTLVEL-SNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLA 196
           DLR DV+ L++L    R+ PV   Q   +A++I A  Y+ECSAL  +N ++++F  A L+
Sbjct: 146 DLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKN-LKEVFDSAILS 204

Query: 197 CV 198
            +
Sbjct: 205 AI 206


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score =  128 bits (322), Expect = 4e-30
 Identities = 70/187 (37%), Positives = 109/187 (58%), Gaps = 10/187 (5%)

Query: 21  NVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSG 80
           ++KC  V+VGDS  GKT+LL  F  + FPE Y PTV+EN      +D  +I L LWDT+G
Sbjct: 4   SIKC--VLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAG 61

Query: 81  SPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLR 140
           +  + ++RPLSY  +D VL+C+ ++   +  ++  KW GEI+   P T +L+V  ++D R
Sbjct: 62  NDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTDQR 121

Query: 141 TDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNK 200
                  E+  HR + V+  +G  +A+ + A  Y+ECSAL S   V+ +F  A    VN+
Sbjct: 122 -------EMGPHRASCVNAMEGKKLAQDVRAKGYLECSAL-SNRGVQQVFECAVRTAVNQ 173

Query: 201 TNKNVKR 207
             +  +R
Sbjct: 174 ARRRNRR 180


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 69/232 (29%), Positives = 111/232 (47%), Gaps = 31/232 (13%)

Query: 18  PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY------VPTVF--ENYTASFEI-- 66
           PN + +KC  VVVGD+  GKT L+   A +     Y      VPTV+  + Y    E+  
Sbjct: 10  PNVETIKC--VVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLE 67

Query: 67  ------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120
                 D   + L LWDT G  + D  R  +Y  SD V++CF I+ P +L+ V   W  E
Sbjct: 68  RSRDVVDEVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPE 125

Query: 121 IQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVSY------DQGANMAKQIGAAT 173
           I+ FCP T ++LVGC+ DLR  D+  +         P+        ++G  +AK++G   
Sbjct: 126 IKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LP 184

Query: 174 YIECSALQSENSVRDIF-HVATLACVNKTNKNVKRNKSQRATKRISHMPSRP 224
           Y E S    +  ++D+F +    A +++ +    ++  ++  K +   P  P
Sbjct: 185 YYETSVF-DQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLP 235


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score = 84.7 bits (208), Expect = 7e-17
 Identities = 73/225 (32%), Positives = 108/225 (48%), Gaps = 40/225 (17%)

Query: 8   QKLSSKS---IMD-------PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY---- 52
           QK SS S   +MD       PN + +KC  VVVGD+  GKT L+   A +     Y    
Sbjct: 12  QKTSSDSMSRLMDSDMDYERPNVETIKC--VVVGDNAVGKTRLICARACNATLTQYQLLA 69

Query: 53  --VPTVF--ENYTASFEI--------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLI 100
             VPTV+  + Y    E+        D   + L LWDT G  + D  R  +Y  SD V++
Sbjct: 70  THVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVL 127

Query: 101 CFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVS- 158
           CF I+ P +L  V   W  EI+ FCP   ++LVGC+ DLR  D+  +         P+  
Sbjct: 128 CFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKP 187

Query: 159 -----YDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV 198
                 ++G  +AK++G   Y E S + ++  ++D+F  A  A +
Sbjct: 188 NEILPPEKGREVAKELG-IPYYETSVV-AQFGIKDVFDNAIRAAL 230


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score = 84.3 bits (207), Expect = 9e-17
 Identities = 66/205 (32%), Positives = 100/205 (48%), Gaps = 30/205 (14%)

Query: 18  PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY------VPTVF--ENYTASFEI-- 66
           PN + +KC  VVVGD+  GKT L+   A +     Y      VPTV+  + Y    E+  
Sbjct: 10  PNVETIKC--VVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE 67

Query: 67  ------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120
                 D   + L LWDT G  + D  R  +Y  SD V++CF I+ P +L  V   W  E
Sbjct: 68  RSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPE 125

Query: 121 IQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVS------YDQGANMAKQIGAAT 173
           I+ FCP   ++LVGC+ DLR  D+  +         P+        ++G  +AK++G   
Sbjct: 126 IKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IP 184

Query: 174 YIECSALQSENSVRDIFHVATLACV 198
           Y E S + ++  ++D+F  A  A +
Sbjct: 185 YYETSVV-AQFGIKDVFDNAIRAAL 208


>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score = 84.3 bits (207), Expect = 9e-17
 Identities = 66/205 (32%), Positives = 100/205 (48%), Gaps = 30/205 (14%)

Query: 18  PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY------VPTVF--ENYTASFEI-- 66
           PN + +KC  VVVGD+  GKT L+   A +     Y      VPTV+  + Y    E+  
Sbjct: 17  PNVETIKC--VVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE 74

Query: 67  ------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120
                 D   + L LWDT G  + D  R  +Y  SD V++CF I+ P +L  V   W  E
Sbjct: 75  RSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPE 132

Query: 121 IQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVS------YDQGANMAKQIGAAT 173
           I+ FCP   ++LVGC+ DLR  D+  +         P+        ++G  +AK++G   
Sbjct: 133 IKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IP 191

Query: 174 YIECSALQSENSVRDIFHVATLACV 198
           Y E S + ++  ++D+F  A  A +
Sbjct: 192 YYETSVV-AQFGIKDVFDNAIRAAL 215


>gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]
          Length = 217

 Score = 79.0 bits (193), Expect = 4e-15
 Identities = 48/182 (26%), Positives = 93/182 (51%), Gaps = 16/182 (8%)

Query: 11  SSKSIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTA-SFEIDTQ 69
           SS    D N +   KI+++GDS  GKT ++  F    + E    T+  ++T  S +ID +
Sbjct: 5   SSARAADENFDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGK 64

Query: 70  RIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEF-CPNT 128
           ++++ +WDT+G   +  +    Y  + A +I +D++R  T +S+   W  EI+++   N 
Sbjct: 65  KVKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESI-PHWIHEIEKYGAANV 123

Query: 129 KMLLVGCKSDLRTDVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRD 188
            ++L+G K DL              +  V ++    +A++ G    +E SA +S+N + +
Sbjct: 124 VIMLIGNKCDL------------WEKRHVLFEDACTLAEKYGLLAVLETSAKESKN-IEE 170

Query: 189 IF 190
           +F
Sbjct: 171 VF 172


>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
           sapiens]
          Length = 205

 Score = 78.6 bits (192), Expect = 5e-15
 Identities = 46/149 (30%), Positives = 82/149 (55%), Gaps = 7/149 (4%)

Query: 14  SIMDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY-TASFEIDTQRIE 72
           S M+P  +   K++++GDS  GK+ LL  FA D + E+Y+ T+  ++   + E+D + I+
Sbjct: 2   SSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIK 61

Query: 73  LSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFC-PNTKML 131
           L +WDT+G   +  +    Y  +  +++ +D++  E+ ++V K+W  EI  +   N   L
Sbjct: 62  LQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNV-KQWLQEIDRYASENVNKL 120

Query: 132 LVGCKSDLRT----DVSTLVELSNHRQTP 156
           LVG K DL T    D +T  E ++    P
Sbjct: 121 LVGNKCDLTTKKVVDYTTAKEFADSLGIP 149


>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score = 77.8 bits (190), Expect = 8e-15
 Identities = 42/128 (32%), Positives = 74/128 (57%), Gaps = 3/128 (2%)

Query: 16  MDPNQNVKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENY-TASFEIDTQRIELS 74
           M+P  +   K++++GDS  GK+ LL  FA D + E+Y+ T+  ++   + E+D + I+L 
Sbjct: 1   MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ 60

Query: 75  LWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFC-PNTKMLLV 133
           +WDT+G   +  +    Y  +  +++ +D++  E+  +V K+W  EI  +   N   LLV
Sbjct: 61  IWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANV-KQWLQEIDRYASENVNKLLV 119

Query: 134 GCKSDLRT 141
           G KSDL T
Sbjct: 120 GNKSDLTT 127


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.129    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,433,427
Number of Sequences: 37866
Number of extensions: 330371
Number of successful extensions: 1125
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 829
Number of HSP's gapped (non-prelim): 214
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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