Search of human proteins with 4758576

Search of human proteins with 4758576

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758576 HUS1 checkpoint protein [Homo sapiens]
         (280 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758576 HUS1 checkpoint protein [Homo sapiens]                     559   e-160
gi|31077215 HUS1 checkpoint protein B [Homo sapiens]                  277   6e-75
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    33   0.36 
gi|221316754 exophilin 5 isoform c [Homo sapiens]                      31   1.4  
gi|221316751 exophilin 5 isoform b [Homo sapiens]                      31   1.4  
gi|221316747 exophilin 5 isoform a [Homo sapiens]                      31   1.4  
gi|5032281 dystrophin Dp427c isoform [Homo sapiens]                    30   3.1  
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]                   30   3.1  
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]                   30   3.1  
gi|5032285 dystrophin Dp427l isoform [Homo sapiens]                    30   3.1  
gi|5032283 dystrophin Dp427m isoform [Homo sapiens]                    30   3.1  
gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]     30   3.1  
gi|14591919 SEC22 vesicle trafficking protein homolog A [Homo sa...    29   5.2  
gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo s...    28   8.9  
gi|113413200 PREDICTED: similar to protein expressed in prostate...    28   8.9  
gi|88953571 PREDICTED: similar to protein expressed in prostate,...    28   8.9  
gi|35493853 otoferlin isoform c [Homo sapiens]                         28   8.9  
gi|35493868 otoferlin isoform b [Homo sapiens]                         28   8.9  
gi|35493860 otoferlin isoform d [Homo sapiens]                         28   8.9  
gi|34740331 otoferlin isoform a [Homo sapiens]                         28   8.9  
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]             28   8.9  
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]         28   8.9  
gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Ho...    28   8.9  

>gi|4758576 HUS1 checkpoint protein [Homo sapiens]
          Length = 280

 Score =  559 bits (1441), Expect = e-160
 Identities = 280/280 (100%), Positives = 280/280 (100%)

Query: 1   MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQ 60
           MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQ
Sbjct: 1   MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQ 60

Query: 61  ENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVELL 120
           ENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVELL
Sbjct: 61  ENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVELL 120

Query: 121 SMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHL 180
           SMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHL
Sbjct: 121 SMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNHL 180

Query: 181 VIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQF 240
           VIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQF
Sbjct: 181 VIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKLLQF 240

Query: 241 LAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPALS 280
           LAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPALS
Sbjct: 241 LAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPALS 280


>gi|31077215 HUS1 checkpoint protein B [Homo sapiens]
          Length = 278

 Score =  277 bits (709), Expect = 6e-75
 Identities = 139/282 (49%), Positives = 200/282 (70%), Gaps = 7/282 (2%)

Query: 1   MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVS---MWCE 57
           MKFRAKI    CL  F  +S  +A+LAK C LR+ PD L F       +GG+    +WCE
Sbjct: 1   MKFRAKITGKGCLELFIHVSGTVARLAKVCVLRVRPDSLCF---GPAGSGGLHEARLWCE 57

Query: 58  LEQENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSV 117
           + Q   F +F+MEGVS + +EI+LELT+E+LSRA ++A  A +LK++LT+K  P LTV+V
Sbjct: 58  VRQ-GAFQQFRMEGVSEDLDEIHLELTAEHLSRAARSAAGASSLKLQLTHKRRPSLTVAV 116

Query: 118 ELLSMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNIS 177
           EL+S    +R V HD+P++V+PR++W+D   P +   D SI LP  +T++S+VE+M N+ 
Sbjct: 117 ELVSSLGRARSVVHDLPVRVLPRRVWRDCLPPSLRASDASIRLPRWRTLRSIVERMANVG 176

Query: 178 NHLVIEANLDGELNLKIETELVCVTTHFKDLGNPPLASESTHEDRNVEHMAEVHIDIRKL 237
           +H+++EANL G + L IETE+V + ++FK+LGNPP ++    E+R++E M +V +D RKL
Sbjct: 177 SHVLVEANLSGRMTLSIETEVVSIQSYFKNLGNPPQSAVGVPENRDLESMVQVRVDNRKL 236

Query: 238 LQFLAGQQVNPTKALCNIVNNKMVHFDLLHEDVSLQYFIPAL 279
           LQFL GQQ++PT ALCNI +N ++   L+ EDVSLQYFIPAL
Sbjct: 237 LQFLEGQQIHPTTALCNIWDNTLLQLVLVQEDVSLQYFIPAL 278


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 32.7 bits (73), Expect = 0.36
 Identities = 27/141 (19%), Positives = 63/141 (44%), Gaps = 12/141 (8%)

Query: 59   EQENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVE 118
            E     NE +   V  +  +  L+ T + L    K AQ    + +++ +       ++ +
Sbjct: 1116 EHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQK 1175

Query: 119  LLSMSSSSRIVTHDIPIKVIPRKLWKDLQEPVVP---------DPDVSIYLPVLKTMKSV 169
            L + ++    +  +I I+   ++  + LQE +           + +  I   ++KT K +
Sbjct: 1176 LTNKNNKIEDLEQEIKIQ---KQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKEL 1232

Query: 170  VEKMKNISNHLVIEANLDGEL 190
             +  +  ++HL+++A+L GEL
Sbjct: 1233 ADSKQAETDHLILQASLKGEL 1253


>gi|221316754 exophilin 5 isoform c [Homo sapiens]
          Length = 1801

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 1/86 (1%)

Query: 72  VSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKH-FPCLTVSVELLSMSSSSRIVT 130
           ++  N +I   +T+ + S AL   QNA+  K KLT  H   C ++ +   ++  SS    
Sbjct: 645 LTVNNEDISRIITNNHWSSALTDTQNAQYSKCKLTPGHKTSCDSLDLSSAALPDSSPSKN 704

Query: 131 HDIPIKVIPRKLWKDLQEPVVPDPDV 156
             +   V+P       + P   DP +
Sbjct: 705 SSLDAPVVPSTTVFSRRSPSDKDPSL 730


>gi|221316751 exophilin 5 isoform b [Homo sapiens]
          Length = 1913

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 1/86 (1%)

Query: 72  VSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKH-FPCLTVSVELLSMSSSSRIVT 130
           ++  N +I   +T+ + S AL   QNA+  K KLT  H   C ++ +   ++  SS    
Sbjct: 757 LTVNNEDISRIITNNHWSSALTDTQNAQYSKCKLTPGHKTSCDSLDLSSAALPDSSPSKN 816

Query: 131 HDIPIKVIPRKLWKDLQEPVVPDPDV 156
             +   V+P       + P   DP +
Sbjct: 817 SSLDAPVVPSTTVFSRRSPSDKDPSL 842


>gi|221316747 exophilin 5 isoform a [Homo sapiens]
          Length = 1989

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 22/86 (25%), Positives = 38/86 (44%), Gaps = 1/86 (1%)

Query: 72  VSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKH-FPCLTVSVELLSMSSSSRIVT 130
           ++  N +I   +T+ + S AL   QNA+  K KLT  H   C ++ +   ++  SS    
Sbjct: 833 LTVNNEDISRIITNNHWSSALTDTQNAQYSKCKLTPGHKTSCDSLDLSSAALPDSSPSKN 892

Query: 131 HDIPIKVIPRKLWKDLQEPVVPDPDV 156
             +   V+P       + P   DP +
Sbjct: 893 SSLDAPVVPSTTVFSRRSPSDKDPSL 918


>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
          Length = 3677

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 46/204 (22%)

Query: 42   ILCDKLANGGV-------------SMWCELEQENFFNEFQMEGV--SAENNEIYLELTSE 86
            IL   L +GGV             S W EL +E    +  +E    SA+  E  L L  E
Sbjct: 1317 ILAQTLTDGGVMDELINEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQE 1376

Query: 87   NLS--------------RALKTAQNARALKIKLTN---------KHFPCLTVSVELLSMS 123
            +L+               A +  Q A+ ++  LT+         KH      +  +LS  
Sbjct: 1377 SLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQI 1436

Query: 124  SSSRIVTHDIPIKVI----PRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNH 179
              ++    D+ +K      P    + LQE  +   +V ++LP L+T     E +++  NH
Sbjct: 1437 DVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNH 1496

Query: 180  LVIEANLDGELN-LKIETELVCVT 202
             V   NL   L+ +K E E+V  T
Sbjct: 1497 CV---NLYKSLSEVKSEVEMVIKT 1517


>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
          Length = 3562

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 46/204 (22%)

Query: 42   ILCDKLANGGV-------------SMWCELEQENFFNEFQMEGV--SAENNEIYLELTSE 86
            IL   L +GGV             S W EL +E    +  +E    SA+  E  L L  E
Sbjct: 1202 ILAQTLTDGGVMDELINEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQE 1261

Query: 87   NLS--------------RALKTAQNARALKIKLTN---------KHFPCLTVSVELLSMS 123
            +L+               A +  Q A+ ++  LT+         KH      +  +LS  
Sbjct: 1262 SLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQI 1321

Query: 124  SSSRIVTHDIPIKVI----PRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNH 179
              ++    D+ +K      P    + LQE  +   +V ++LP L+T     E +++  NH
Sbjct: 1322 DVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNH 1381

Query: 180  LVIEANLDGELN-LKIETELVCVT 202
             V   NL   L+ +K E E+V  T
Sbjct: 1382 CV---NLYKSLSEVKSEVEMVIKT 1402


>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
          Length = 3681

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 46/204 (22%)

Query: 42   ILCDKLANGGV-------------SMWCELEQENFFNEFQMEGV--SAENNEIYLELTSE 86
            IL   L +GGV             S W EL +E    +  +E    SA+  E  L L  E
Sbjct: 1321 ILAQTLTDGGVMDELINEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQE 1380

Query: 87   NLS--------------RALKTAQNARALKIKLTN---------KHFPCLTVSVELLSMS 123
            +L+               A +  Q A+ ++  LT+         KH      +  +LS  
Sbjct: 1381 SLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQI 1440

Query: 124  SSSRIVTHDIPIKVI----PRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNH 179
              ++    D+ +K      P    + LQE  +   +V ++LP L+T     E +++  NH
Sbjct: 1441 DVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNH 1500

Query: 180  LVIEANLDGELN-LKIETELVCVT 202
             V   NL   L+ +K E E+V  T
Sbjct: 1501 CV---NLYKSLSEVKSEVEMVIKT 1521


>gi|5032285 dystrophin Dp427l isoform [Homo sapiens]
          Length = 3562

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 46/204 (22%)

Query: 42   ILCDKLANGGV-------------SMWCELEQENFFNEFQMEGV--SAENNEIYLELTSE 86
            IL   L +GGV             S W EL +E    +  +E    SA+  E  L L  E
Sbjct: 1202 ILAQTLTDGGVMDELINEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQE 1261

Query: 87   NLS--------------RALKTAQNARALKIKLTN---------KHFPCLTVSVELLSMS 123
            +L+               A +  Q A+ ++  LT+         KH      +  +LS  
Sbjct: 1262 SLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQI 1321

Query: 124  SSSRIVTHDIPIKVI----PRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNH 179
              ++    D+ +K      P    + LQE  +   +V ++LP L+T     E +++  NH
Sbjct: 1322 DVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNH 1381

Query: 180  LVIEANLDGELN-LKIETELVCVT 202
             V   NL   L+ +K E E+V  T
Sbjct: 1382 CV---NLYKSLSEVKSEVEMVIKT 1402


>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
          Length = 3685

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 51/204 (25%), Positives = 81/204 (39%), Gaps = 46/204 (22%)

Query: 42   ILCDKLANGGV-------------SMWCELEQENFFNEFQMEGV--SAENNEIYLELTSE 86
            IL   L +GGV             S W EL +E    +  +E    SA+  E  L L  E
Sbjct: 1325 ILAQTLTDGGVMDELINEELETFNSRWRELHEEAVRRQKLLEQSIQSAQETEKSLHLIQE 1384

Query: 87   NLS--------------RALKTAQNARALKIKLTN---------KHFPCLTVSVELLSMS 123
            +L+               A +  Q A+ ++  LT+         KH      +  +LS  
Sbjct: 1385 SLTFIDKQLAAYIADKVDAAQMPQEAQKIQSDLTSHEISLEEMKKHNQGKEAAQRVLSQI 1444

Query: 124  SSSRIVTHDIPIKVI----PRKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEKMKNISNH 179
              ++    D+ +K      P    + LQE  +   +V ++LP L+T     E +++  NH
Sbjct: 1445 DVAQKKLQDVSMKFRLFQKPANFEQRLQESKMILDEVKMHLPALETKSVEQEVVQSQLNH 1504

Query: 180  LVIEANLDGELN-LKIETELVCVT 202
             V   NL   L+ +K E E+V  T
Sbjct: 1505 CV---NLYKSLSEVKSEVEMVIKT 1525


>gi|22094135 DOT1-like, histone H3 methyltransferase [Homo sapiens]
          Length = 1537

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 57  ELEQENFFNEFQ-MEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTV 115
           +LEQ+N     Q ++ + A   E+ L+  + +L + LK  Q   ALK +++ K   CL +
Sbjct: 584 QLEQDNRALRGQSLQLLKARCEELQLDWATLSLEKLLKEKQ---ALKSQISEKQRHCLEL 640

Query: 116 SVELLSMSSSSR 127
            + ++ +  S R
Sbjct: 641 QISIVELEKSQR 652


>gi|14591919 SEC22 vesicle trafficking protein homolog A [Homo
          sapiens]
          Length = 307

 Score = 28.9 bits (63), Expect = 5.2
 Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 12/72 (16%)

Query: 12 CLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVS--MWCELEQEN-----FF 64
          C  +F  +S  +A+L   CTL+     +NFI     ++ GVS  M C     N     F 
Sbjct: 33 CRKYFKMLSRKLAQLPDRCTLKTGHYNINFI-----SSLGVSYMMLCTENYPNVLAFSFL 87

Query: 65 NEFQMEGVSAEN 76
          +E Q E ++  N
Sbjct: 88 DELQKEFITTYN 99


>gi|239745140 PREDICTED: similar to hect domain and RLD 2 [Homo
           sapiens]
          Length = 1052

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 33/155 (21%), Positives = 66/155 (42%), Gaps = 23/155 (14%)

Query: 59  EQENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVE 118
           ++E F  + +     AE   I+ EL +EN S AL+  Q  + L+ KL       +  +  
Sbjct: 391 QEERFXEQHKRLQQLAEPQSIFKELNNENKS-ALQLEQQVKELQEKLGE-----VKDTEH 444

Query: 119 LLSMSSSSRIVTHDIPIKVIP------RKLWKDLQEPVVPDPDVSIYLPVLKTMKSVVEK 172
           L + S  ++ +T  + +  +P        L  D +E   P P V   L   + M S +++
Sbjct: 445 LEAASQQNQQLTAQLSLMALPGEGHGGEHLDSDGEEAPRPMPSVPEDLESREAMSSFMDQ 504

Query: 173 MKNISNHLVIEANLDGELNLKIETELVCVTTHFKD 207
           ++              +L+  ++ + +C   H++D
Sbjct: 505 LEE-----------KADLSELVKKKELCFIHHWRD 528


>gi|113413200 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 [Homo sapiens]
          Length = 1038

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 4/49 (8%)

Query: 56  CELEQENFFNEFQMEGVSAENN--EIYLELTSENLSRALKTAQNARALK 102
           CEL  +  + E QM   S+EN+  E  L+LTSE  S+ LK ++N +  K
Sbjct: 435 CELVSD--YKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEK 481


>gi|88953571 PREDICTED: similar to protein expressed in prostate,
           ovary, testis, and placenta 2 isoform 2 [Homo sapiens]
          Length = 1075

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 4/49 (8%)

Query: 56  CELEQENFFNEFQMEGVSAENN--EIYLELTSENLSRALKTAQNARALK 102
           CEL  +  + E QM   S+EN+  E  L+LTSE  S+ LK ++N +  K
Sbjct: 472 CELVSD--YKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEK 518


>gi|35493853 otoferlin isoform c [Homo sapiens]
          Length = 1307

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 13   LNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQENFFNEFQMEG- 71
            LN F R     AK AK CT+ ++  +++  L        V  W  L   N  +EF++ G 
Sbjct: 1161 LNRFPRG----AKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK 1216

Query: 72   VSAENNEIYLELTSEN 87
            V AE + +  E   +N
Sbjct: 1217 VEAELHLLTAEEAEKN 1232


>gi|35493868 otoferlin isoform b [Homo sapiens]
          Length = 1230

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 13   LNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQENFFNEFQMEG- 71
            LN F R     AK AK CT+ ++  +++  L        V  W  L   N  +EF++ G 
Sbjct: 1084 LNRFPRG----AKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK 1139

Query: 72   VSAENNEIYLELTSEN 87
            V AE + +  E   +N
Sbjct: 1140 VEAELHLLTAEEAEKN 1155


>gi|35493860 otoferlin isoform d [Homo sapiens]
          Length = 1230

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 13   LNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQENFFNEFQMEG- 71
            LN F R     AK AK CT+ ++  +++  L        V  W  L   N  +EF++ G 
Sbjct: 1084 LNRFPRG----AKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK 1139

Query: 72   VSAENNEIYLELTSEN 87
            V AE + +  E   +N
Sbjct: 1140 VEAELHLLTAEEAEKN 1155


>gi|34740331 otoferlin isoform a [Homo sapiens]
          Length = 1997

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 5/76 (6%)

Query: 13   LNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVSMWCELEQENFFNEFQMEG- 71
            LN F R     AK AK CT+ ++  +++  L        V  W  L   N  +EF++ G 
Sbjct: 1851 LNRFPRG----AKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGK 1906

Query: 72   VSAENNEIYLELTSEN 87
            V AE + +  E   +N
Sbjct: 1907 VEAELHLLTAEEAEKN 1922


>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
          Length = 4981

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 5/47 (10%)

Query: 172  KMKNISNHLVIEANLDGELNLKIETELVCVTTHFKDLGNPPLASEST 218
            K+ N +  + + ++L  +LN         +T   KD GNPPL+S++T
Sbjct: 3033 KLDNDTGWISVASSLISDLNQNF-----FITVTAKDKGNPPLSSQAT 3074


>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
          Length = 958

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 7/90 (7%)

Query: 60  QENFFNEFQMEGVSAENNEIYLELTSENLSRALKTA--QNARALKIKLTNKHFPCLTVSV 117
           Q N   E Q  G       + L   + NL +A+ +        L++ L + HF  L VS 
Sbjct: 489 QYNLIREIQ-SGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSG 547

Query: 118 ELLSMSSSSRIVTHDIP----IKVIPRKLW 143
            L  + S  +I  HD P      ++  KLW
Sbjct: 548 VLDQLKSLIQIDLHDNPWDCTCDIVGMKLW 577


>gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Homo
           sapiens]
          Length = 304

 Score = 28.1 bits (61), Expect = 8.9
 Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 5/60 (8%)

Query: 86  ENLSRALKTAQNARALKIKLTNKHFPCLTVSVELLSMSSSSRIVTHDIPIKVIPRKLWKD 145
           E   RA +T      L++K  +K  P L     +L MSS   I TH +P  +IP  +WK+
Sbjct: 76  EKCKRA-QTLDRHAFLELKFPHKEKPDLEF---VLEMSSPQLIKTH-LPSHLIPPSIWKE 130


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,584,811
Number of Sequences: 37866
Number of extensions: 375116
Number of successful extensions: 1048
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1045
Number of HSP's gapped (non-prelim): 23
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.