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Search of human proteins with 4758528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
(777 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 1559 0.0
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens] 96 1e-19
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens] 91 5e-18
gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens] 87 6e-17
gi|209180457 target of myb1 isoform 2 [Homo sapiens] 86 2e-16
gi|4885637 target of myb1 isoform 1 [Homo sapiens] 86 2e-16
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 80 9e-15
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 75 2e-13
gi|209180448 target of myb1 isoform 3 [Homo sapiens] 75 2e-13
gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens] 75 2e-13
gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens] 75 2e-13
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 72 2e-12
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 72 2e-12
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 72 2e-12
gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo... 71 3e-12
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b... 69 2e-11
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ... 69 2e-11
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 67 6e-11
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 67 6e-11
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 65 2e-10
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 65 2e-10
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 65 3e-10
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 65 3e-10
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 65 3e-10
gi|209180450 target of myb1 isoform 4 [Homo sapiens] 65 3e-10
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 65 3e-10
gi|56549694 enabled homolog isoform a [Homo sapiens] 64 4e-10
gi|39930375 enabled homolog isoform b [Homo sapiens] 64 4e-10
gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens] 64 7e-10
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 62 2e-09
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 1559 bits (4036), Expect = 0.0
Identities = 777/777 (100%), Positives = 777/777 (100%)
Query: 1 MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHV 60
MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHV
Sbjct: 1 MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHV 60
Query: 61 ALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFR 120
ALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFR
Sbjct: 61 ALYALEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFR 120
Query: 121 NEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKH 180
NEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKH
Sbjct: 121 NEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVMTRKH 180
Query: 181 HCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTS 240
HCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTS
Sbjct: 181 HCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKATSTTELPPEYLTS 240
Query: 241 PLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASS 300
PLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASS
Sbjct: 241 PLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASS 300
Query: 301 APPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQ 360
APPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQ
Sbjct: 301 APPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQ 360
Query: 361 PGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFV 420
PGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFV
Sbjct: 361 PGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEPQFHNGESEESHEQFLKALQNAVTTFV 420
Query: 421 NRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDA 480
NRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDA
Sbjct: 421 NRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDA 480
Query: 481 RGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQE 540
RGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQE
Sbjct: 481 RGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQE 540
Query: 541 KERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVE 600
KERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVE
Sbjct: 541 KERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVE 600
Query: 601 GSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAY 660
GSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAY
Sbjct: 601 GSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAAPQAQAGPTASPAY 660
Query: 661 SSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPS 720
SSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPS
Sbjct: 661 SSYQPTPTAGYQNVASQAPQSLPAISQPPQSSTMGYMGSQSVSMGYQPYNMQNLMTTLPS 720
Query: 721 QDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD 777
QDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD
Sbjct: 721 QDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQPPVAQQPQAQGPPAQGSEAQLISFD 777
>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
Length = 525
Score = 95.9 bits (237), Expect = 1e-19
Identities = 47/136 (34%), Positives = 78/136 (57%)
Query: 8 FERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEV 67
FE+ ++KAT++ DW I+ ICD + AK + +I K+VN K PHVAL AL +
Sbjct: 9 FEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQALTL 68
Query: 68 MESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKV 127
+ + V NCG+ H EV ++ E++ ++K + V K+ L+ W+ F+ +P++ +
Sbjct: 69 LGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEFQKDPQFSL 128
Query: 128 VQDTYQIMKVEGHVFP 143
+ T + MK EG FP
Sbjct: 129 ISATIKSMKEEGITFP 144
>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
Length = 540
Score = 90.5 bits (223), Expect = 5e-18
Identities = 46/136 (33%), Positives = 78/136 (57%), Gaps = 1/136 (0%)
Query: 8 FERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEV 67
F++ ++KATS++ DW IL ICD + Q T K + SI ++VN K+PHVA+ AL +
Sbjct: 9 FDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTL 68
Query: 68 MESVVKNCGQTVHDEVANKQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKV 127
+ + V NCG+ H EV ++ E+ ++L + V K+ L+ W F+N+P+ +
Sbjct: 69 LGACVSNCGKIFHLEVCSRDFASEVSNVLNKG-HPKVCEKLKALMVEWTDEFKNDPQLSL 127
Query: 128 VQDTYQIMKVEGHVFP 143
+ + +K +G FP
Sbjct: 128 ISAMIKNLKEQGVTFP 143
Score = 31.6 bits (70), Expect = 2.9
Identities = 44/151 (29%), Positives = 60/151 (39%), Gaps = 30/151 (19%)
Query: 635 YMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAISQ---PPQS 691
YM +G +G+Q AGP S AY + Q+ S P+ L ++SQ PP +
Sbjct: 393 YMQSSGVSGSQV----YAGPPPSGAYLVAGNAQMSHLQSY-SLPPEQLSSLSQAVVPPSA 447
Query: 692 STMGYMGSQSVSMGYQPYNMQNLM-TTLPSQDA--SLPPQQPYIAGQQP--MYQQMAP-- 744
+ + SQ Y + ++ T PSQ S PP A +YQ P
Sbjct: 448 NPA--LPSQQTQAAYPNTMVSSVQGNTYPSQAPVYSPPPAATAAAATADVTLYQNAGPNM 505
Query: 745 ---------SGGPPQ----QQPPVAQQPQAQ 762
S PQ QQPP QQP +Q
Sbjct: 506 PQVPNYNLTSSTLPQPGGSQQPPQPQQPYSQ 536
>gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]
Length = 507
Score = 87.0 bits (214), Expect = 6e-17
Identities = 50/136 (36%), Positives = 78/136 (57%), Gaps = 4/136 (2%)
Query: 12 LDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVN-DKNPHVALYALEVMES 70
L+KAT L DW ++ICD+I + + K A+ ++KK++N ++N + AL V+E+
Sbjct: 17 LEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYREVMLALTVLET 76
Query: 71 VVKNCGQTVHDEVANKQTMEELKDLL---KRQVEVNVRNKILYLIQAWAHAFRNEPKYKV 127
VKNCG H VAN+ ++ + + K V++K+L LIQAWA AFR+ P
Sbjct: 77 CVKNCGHRFHILVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWADAFRSSPDLTG 136
Query: 128 VQDTYQIMKVEGHVFP 143
V Y+ +K +G FP
Sbjct: 137 VVHIYEELKRKGVEFP 152
>gi|209180457 target of myb1 isoform 2 [Homo sapiens]
Length = 493
Score = 85.5 bits (210), Expect = 2e-16
Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 4/136 (2%)
Query: 12 LDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKK-VNDKNPHVALYALEVMES 70
++KAT L DW ++ICD+I + + K A+ ++KK+ V +KN H + AL V+E+
Sbjct: 17 IEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLET 76
Query: 71 VVKNCGQTVHDEVANKQTMEEL---KDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKV 127
VKNCG H VA++ +E + L K V +K+L LIQ+WA AFR+ P
Sbjct: 77 CVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTG 136
Query: 128 VQDTYQIMKVEGHVFP 143
V Y+ ++ +G FP
Sbjct: 137 VVTIYEDLRRKGLEFP 152
>gi|4885637 target of myb1 isoform 1 [Homo sapiens]
Length = 492
Score = 85.5 bits (210), Expect = 2e-16
Identities = 50/136 (36%), Positives = 77/136 (56%), Gaps = 4/136 (2%)
Query: 12 LDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKK-VNDKNPHVALYALEVMES 70
++KAT L DW ++ICD+I + + K A+ ++KK+ V +KN H + AL V+E+
Sbjct: 17 IEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLET 76
Query: 71 VVKNCGQTVHDEVANKQTMEEL---KDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKV 127
VKNCG H VA++ +E + L K V +K+L LIQ+WA AFR+ P
Sbjct: 77 CVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTG 136
Query: 128 VQDTYQIMKVEGHVFP 143
V Y+ ++ +G FP
Sbjct: 137 VVTIYEDLRRKGLEFP 152
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 79.7 bits (195), Expect = 9e-15
Identities = 32/64 (50%), Positives = 41/64 (64%)
Query: 156 RAPDWVDAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPC 215
+ P W D C+ C +FGV TRKHHCR CG++ C KCS+K I KF + K VRVC C
Sbjct: 1101 KEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKPVRVCNIC 1160
Query: 216 YEQL 219
++ L
Sbjct: 1161 FDVL 1164
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 75.5 bits (184), Expect = 2e-13
Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 10/120 (8%)
Query: 107 KILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAA-------ERAPD 159
K L+ + A ++ K + V T + +E + S + AA E P+
Sbjct: 754 KTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSELAAKTRDGDFEDPPE 813
Query: 160 WVDAEECH---RCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCY 216
WV E C C+ F V+ RKHHCR+CG+IFC +CSS + +P++G K VRVC CY
Sbjct: 814 WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
>gi|209180448 target of myb1 isoform 3 [Homo sapiens]
Length = 460
Score = 75.5 bits (184), Expect = 2e-13
Identities = 44/119 (36%), Positives = 69/119 (57%), Gaps = 4/119 (3%)
Query: 29 LQICDLIRQGDTQAKYAVNSIKKK-VNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQ 87
++ICD+I + + K A+ ++KK+ V +KN H + AL V+E+ VKNCG H VA++
Sbjct: 1 MEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQD 60
Query: 88 TMEEL---KDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
+E + L K V +K+L LIQ+WA AFR+ P V Y+ ++ +G FP
Sbjct: 61 FVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGLEFP 119
>gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]
Length = 400
Score = 75.5 bits (184), Expect = 2e-13
Identities = 32/76 (42%), Positives = 45/76 (59%), Gaps = 11/76 (14%)
Query: 155 ERAPDWVDAEECHRCRVQF-----------GVMTRKHHCRACGQIFCGKCSSKYSTIPKF 203
+ P+W+D++ C +C F + R+HHCR CG+ CGKCSSK S+IP
Sbjct: 276 QETPEWLDSDSCQKCDQPFFWNFKQMWDSKKIGLRQHHCRKCGKAVCGKCSSKRSSIPLM 335
Query: 204 GIEKEVRVCEPCYEQL 219
G E EVRVC+ C+E +
Sbjct: 336 GFEFEVRVCDSCHEAI 351
>gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]
Length = 410
Score = 75.5 bits (184), Expect = 2e-13
Identities = 32/76 (42%), Positives = 44/76 (57%), Gaps = 11/76 (14%)
Query: 155 ERAPDWVDAEECHRCRVQF-----------GVMTRKHHCRACGQIFCGKCSSKYSTIPKF 203
E AP W++++ C +C F + R+HHCR CGQ CGKCSSK S+ P
Sbjct: 276 EEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVM 335
Query: 204 GIEKEVRVCEPCYEQL 219
G E +VRVC+ CY+ +
Sbjct: 336 GFEFQVRVCDSCYDSI 351
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 72.4 bits (176), Expect = 2e-12
Identities = 79/305 (25%), Positives = 124/305 (40%), Gaps = 33/305 (10%)
Query: 484 LSALREEHREKLRRAAEEAERQR---QIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQ--- 537
L+A+ E + L E + ++ +++ ++LE + +++E LE QRQ + Q
Sbjct: 876 LAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFH 935
Query: 538 -EQEKERQMRLEQQ--KQTVQMRAQMP------AFPLPYAQLQAMPAAGGVLYQPSGPAS 588
EQ K +MR QQ +Q Q + Q P + P+P PA G+ P+
Sbjct: 936 MEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAPASVVP 995
Query: 589 FPS-TFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAADPSMVSAYMYPAGATGAQAA 647
P+ + +P GS+ S G Q AGP P+ A P V + P G G
Sbjct: 996 APAGSGAPPGSLGPSEQIG----QAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPF 1051
Query: 648 PQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLP---AISQPPQSSTMGYMGSQSVSM 704
P Q P+ P P +G+ VA AP LP PP + ++ GS + S+
Sbjct: 1052 PNQQTPPSMMPG-----AVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPSIIPFGSLADSI 1106
Query: 705 GYQ---PYNMQNLMTTLPSQDASLPPQQPYIAGQQPMYQQMAPSGGPPQQQP--PVAQQP 759
P N+ LP +LPP ++ P++ + + P P P
Sbjct: 1107 SINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSA 1166
Query: 760 QAQGP 764
AQ P
Sbjct: 1167 AAQSP 1171
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 72.0 bits (175), Expect = 2e-12
Identities = 42/126 (33%), Positives = 60/126 (47%), Gaps = 21/126 (16%)
Query: 143 PEFKESDAMFAAERAPDWV---DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYST 199
PE + + ++ P WV +A C C+V+F R+HHCRACG++FCG C ++
Sbjct: 727 PENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCK 786
Query: 200 IPKFGIEKEVRVCEPCYEQL---------------NRKAEGKATSTTELPP-EYLTSPLS 243
+ +EKE RVC CYE + N K+ TT PP E TS +
Sbjct: 787 LQY--LEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIP 844
Query: 244 QQSQLP 249
+ LP
Sbjct: 845 SPATLP 850
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 72.0 bits (175), Expect = 2e-12
Identities = 42/126 (33%), Positives = 60/126 (47%), Gaps = 21/126 (16%)
Query: 143 PEFKESDAMFAAERAPDWV---DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYST 199
PE + + ++ P WV +A C C+V+F R+HHCRACG++FCG C ++
Sbjct: 727 PENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCK 786
Query: 200 IPKFGIEKEVRVCEPCYEQL---------------NRKAEGKATSTTELPP-EYLTSPLS 243
+ +EKE RVC CYE + N K+ TT PP E TS +
Sbjct: 787 LQY--LEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIP 844
Query: 244 QQSQLP 249
+ LP
Sbjct: 845 SPATLP 850
>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
[Homo sapiens]
Length = 723
Score = 71.2 bits (173), Expect = 3e-12
Identities = 44/140 (31%), Positives = 71/140 (50%), Gaps = 8/140 (5%)
Query: 7 TFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALE 66
+ E L+KAT+ + DWE I+ CD I + + AV + K+ AL AL
Sbjct: 8 SLESWLNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQALT 67
Query: 67 VMESVVKNCGQTVHDEVANKQTMEEL-----KDLLKRQVEVNVRNKILYLIQAWAHAFRN 121
V+E+ +KNCG+ H+EV + + EL L +V V+ K++ L+ +W A
Sbjct: 68 VLEACMKNCGRRFHNEVGKFRFLNELIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALPE 127
Query: 122 EPKYKVVQDTYQIMKVEGHV 141
E K ++D Y ++K +G V
Sbjct: 128 EAK---IKDAYHMLKRQGIV 144
>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 1 [Homo sapiens]
Length = 639
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 8/148 (5%)
Query: 7 TFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALE 66
T E +++AT+ L E DW SI C+ + + A + K+ A+ AL
Sbjct: 9 TLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALT 68
Query: 67 VMESVVKNCGQTVHDEVANKQTMEEL-----KDLLKRQVEVNVRNKILYLIQAWAHAFRN 121
V+E+ +K+CG+ HDEV + + EL L + V+NKIL L+ +W
Sbjct: 69 VLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPE 128
Query: 122 EPKYKVVQDTYQIMKVEGHVFPEFKESD 149
E K + + YQ++K +G V + K D
Sbjct: 129 EVK---IAEAYQMLKKQGIVKSDPKLPD 153
>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
binding protein 1 isoform 2 [Homo sapiens]
Length = 552
Score = 68.6 bits (166), Expect = 2e-11
Identities = 44/148 (29%), Positives = 71/148 (47%), Gaps = 8/148 (5%)
Query: 7 TFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALE 66
T E +++AT+ L E DW SI C+ + + A + K+ A+ AL
Sbjct: 9 TLEARINRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQALT 68
Query: 67 VMESVVKNCGQTVHDEVANKQTMEEL-----KDLLKRQVEVNVRNKILYLIQAWAHAFRN 121
V+E+ +K+CG+ HDEV + + EL L + V+NKIL L+ +W
Sbjct: 69 VLETCMKSCGKRFHDEVGKFRFLNELIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPE 128
Query: 122 EPKYKVVQDTYQIMKVEGHVFPEFKESD 149
E K + + YQ++K +G V + K D
Sbjct: 129 EVK---IAEAYQMLKKQGIVKSDPKLPD 153
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 67.0 bits (162), Expect = 6e-11
Identities = 31/69 (44%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 157 APDWVDAE---ECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCE 213
A WV E C C V+F + R+HHCR CGQ+FC KCS S I + I VRVC+
Sbjct: 203 ADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQ 262
Query: 214 PCYEQLNRK 222
CY L +
Sbjct: 263 NCYYNLQHE 271
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 67.0 bits (162), Expect = 6e-11
Identities = 31/69 (44%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 157 APDWVDAE---ECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCE 213
A WV E C C V+F + R+HHCR CGQ+FC KCS S I + I VRVC+
Sbjct: 3448 ADHWVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQ 3507
Query: 214 PCYEQLNRK 222
CY L +
Sbjct: 3508 NCYYNLQHE 3516
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 65.1 bits (157), Expect = 2e-10
Identities = 30/65 (46%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 154 AERAPDWVDAEE---CHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVR 210
A R WV E CH CR +F + KHHCRACGQ FC +CS +P G + VR
Sbjct: 291 AARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVR 350
Query: 211 VCEPC 215
VC C
Sbjct: 351 VCFNC 355
Score = 59.7 bits (143), Expect = 1e-08
Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 166 CHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGI-EKEVRVCEPCYEQLN 220
C++C F KHHCRACG+ FC CSSK +P+ G VRVC+ CYE N
Sbjct: 189 CNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARN 244
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 65.1 bits (157), Expect = 2e-10
Identities = 30/65 (46%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 154 AERAPDWVDAEE---CHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVR 210
A R WV E CH CR +F + KHHCRACGQ FC +CS +P G + VR
Sbjct: 706 AARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPVR 765
Query: 211 VCEPC 215
VC C
Sbjct: 766 VCFNC 770
Score = 59.7 bits (143), Expect = 1e-08
Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 166 CHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGI-EKEVRVCEPCYEQLN 220
C++C F KHHCRACG+ FC CSSK +P+ G VRVC+ CYE N
Sbjct: 604 CNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARN 659
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 64.7 bits (156), Expect = 3e-10
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 162 DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNR 221
+A C +C +F + RKHHCR CG IFC CSS +P + K VRVC+ C+ L +
Sbjct: 536 EATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY--PKPVRVCDSCHTLLLQ 593
Query: 222 KAEGKAT 228
+ A+
Sbjct: 594 RCSSTAS 600
Score = 32.0 bits (71), Expect = 2.3
Identities = 37/160 (23%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 396 FHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLE 455
FH ++ ES L+ A+T+F K+N + + + ++ G + +
Sbjct: 359 FHKAQNAESS---LQQKNEAITSFEG--KTNQVMSSMKQMEERLQHSERARQGAEERSHK 413
Query: 456 LLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLE 515
L +L R LQ +L+Q+ + +L +E EK +R A + E Q + +
Sbjct: 414 LQQELGGR---IGALQLQLSQLHEQCSSLE--KELKSEKEQRQALQRELQHEKDTSS--- 465
Query: 516 IMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQ 555
++R + Q+ ++++L + LQ+++ E Q E+Q+Q +Q
Sbjct: 466 LLRMELQQVEGLKKEL--RELQDEKAELQKICEEQEQALQ 503
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 64.7 bits (156), Expect = 3e-10
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 162 DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNR 221
+A C +C +F + RKHHCR CG IFC CSS +P + K VRVC+ C+ L +
Sbjct: 536 EATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY--PKPVRVCDSCHTLLLQ 593
Query: 222 KAEGKAT 228
+ A+
Sbjct: 594 RCSSTAS 600
Score = 32.0 bits (71), Expect = 2.3
Identities = 37/160 (23%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 396 FHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLE 455
FH ++ ES L+ A+T+F K+N + + + ++ G + +
Sbjct: 359 FHKAQNAESS---LQQKNEAITSFEG--KTNQVMSSMKQMEERLQHSERARQGAEERSHK 413
Query: 456 LLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLE 515
L +L R LQ +L+Q+ + +L +E EK +R A + E Q + +
Sbjct: 414 LQQELGGR---IGALQLQLSQLHEQCSSLE--KELKSEKEQRQALQRELQHEKDTSS--- 465
Query: 516 IMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQ 555
++R + Q+ ++++L + LQ+++ E Q E+Q+Q +Q
Sbjct: 466 LLRMELQQVEGLKKEL--RELQDEKAELQKICEEQEQALQ 503
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 64.7 bits (156), Expect = 3e-10
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 162 DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNR 221
+A C +C +F + RKHHCR CG IFC CSS +P + K VRVC+ C+ L +
Sbjct: 644 EATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSY--PKPVRVCDSCHTLLLQ 701
Query: 222 KAEGKAT 228
+ A+
Sbjct: 702 RCSSTAS 708
Score = 32.0 bits (71), Expect = 2.3
Identities = 37/160 (23%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 396 FHNGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLE 455
FH ++ ES L+ A+T+F K+N + + + ++ G + +
Sbjct: 467 FHKAQNAESS---LQQKNEAITSFEG--KTNQVMSSMKQMEERLQHSERARQGAEERSHK 521
Query: 456 LLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLE 515
L +L R LQ +L+Q+ + +L +E EK +R A + E Q + +
Sbjct: 522 LQQELGGR---IGALQLQLSQLHEQCSSLE--KELKSEKEQRQALQRELQHEKDTSS--- 573
Query: 516 IMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQ 555
++R + Q+ ++++L + LQ+++ E Q E+Q+Q +Q
Sbjct: 574 LLRMELQQVEGLKKEL--RELQDEKAELQKICEEQEQALQ 611
>gi|209180450 target of myb1 isoform 4 [Homo sapiens]
Length = 447
Score = 64.7 bits (156), Expect = 3e-10
Identities = 39/106 (36%), Positives = 60/106 (56%), Gaps = 4/106 (3%)
Query: 12 LDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKK-VNDKNPHVALYALEVMES 70
++KAT L DW ++ICD+I + + K A+ ++KK+ V +KN H + AL V+E+
Sbjct: 17 IEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLET 76
Query: 71 VVKNCGQTVHDEVANKQTMEEL---KDLLKRQVEVNVRNKILYLIQ 113
VKNCG H VA++ +E + L K V +K+L LIQ
Sbjct: 77 CVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQ 122
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 64.7 bits (156), Expect = 3e-10
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 30/219 (13%)
Query: 9 ERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVM 68
+RL +Q+ E + E LQ C + + D S++K+++ K L LE
Sbjct: 436 QRLQQAEKAQMEAEDEDEKYLQEC--LSKSD--------SLQKQISQKEKQ--LVQLETD 483
Query: 69 ESVVKNCGQTVHDEVAN-KQTMEELKDLLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKV 127
+ K QT+ +++ K + L++ + Q ++++ + L L N+ K+
Sbjct: 484 LKIEKEWRQTLQEDLQKEKDALSHLRN--ETQQIISLKKEFLNLQD------ENQQLKKI 535
Query: 128 VQDTYQIMKVEGHVFPEFK-ESDAMFAAERAPD---WV---DAEECHRCRVQFGVMTRKH 180
+ Q ++ G+ E K + + + A +A W+ +A C C +F + RKH
Sbjct: 536 YHEQEQALQELGNKLSESKLKIEDIKEANKALQGLVWLKDKEATHCKLCEKEFSLSKRKH 595
Query: 181 HCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQL 219
HCR CG+IFC CS +P K VRVC+ C+ L
Sbjct: 596 HCRNCGEIFCNACSDNELPLP--SSPKPVRVCDSCHALL 632
Score = 30.4 bits (67), Expect = 6.6
Identities = 32/139 (23%), Positives = 60/139 (43%), Gaps = 15/139 (10%)
Query: 436 DSAVLSLFQSINGMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKL 495
+S V SL ++ + +L+ +L + LQ++ Q+R + ++H E +
Sbjct: 252 NSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLE-V 310
Query: 496 RRAAEEAERQRQIQLAQKLEIM--------RQKKQEYLEVQRQLAIQRLQEQEKERQMRL 547
+ E E Q Q L+ M R + Q +V+ +LA+Q + E E M+L
Sbjct: 311 TKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKL 370
Query: 548 ------EQQKQTVQMRAQM 560
E+Q + +R Q+
Sbjct: 371 LEKDIHEKQDTLIGLRQQL 389
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 64.3 bits (155), Expect = 4e-10
Identities = 79/315 (25%), Positives = 130/315 (41%), Gaps = 32/315 (10%)
Query: 398 NGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELL 457
N S+E F A+ +A+ ++ G ++ ++ L Q NG + LE+
Sbjct: 90 NFGSKEDANVFASAMMHALEVL-----NSQETGPTLPRQNSQLPA-QVQNGPSQEELEIQ 143
Query: 458 N-QLDERRLYYEGLQDKLAQIRDARGALSALREEH---------REKLRRAAEEAERQRQ 507
QL E++ E +++L + R R L R E +E+L R +E ERQ +
Sbjct: 144 RRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQER 203
Query: 508 IQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPY 567
++ ++LE +QE LE Q +L +R + QE+ER RLE+++Q + + Q+ L +
Sbjct: 204 LERQERLE-----RQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEW 258
Query: 568 AQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAA 627
+ + + +A + PAS +P SV G Q A PS
Sbjct: 259 ERERRISSA-------AAPASVE---TPLNSVLGDSSASEPGLQAASQPAETPSQQGIVL 308
Query: 628 DP-SMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAIS 686
P + P G A A GP P S P P + +Q P P
Sbjct: 309 GPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368
Query: 687 QPPQSSTMGYMGSQS 701
PP ++ ++ S S
Sbjct: 369 APPLPASGFFLASMS 383
Score = 33.1 bits (74), Expect = 1.0
Identities = 43/157 (27%), Positives = 62/157 (39%), Gaps = 19/157 (12%)
Query: 242 LSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSA 301
L +Q +L +R E +E +E Q L + E E +ER RQ+ + E SSA
Sbjct: 210 LERQERL--ERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSA 267
Query: 302 PPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPV----PLTEP 357
+S+ +P+NS + +P L Q ++ + TPS PL P
Sbjct: 268 AAPASV-ETPLNSVLGDSSASEPGL------------QAASQPAETPSQQGIVLGPLAPP 314
Query: 358 AAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEP 394
P A +V P P P PS GP P
Sbjct: 315 PPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPP 351
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 64.3 bits (155), Expect = 4e-10
Identities = 79/315 (25%), Positives = 130/315 (41%), Gaps = 32/315 (10%)
Query: 398 NGESEESHEQFLKALQNAVTTFVNRMKSNHMRGRSITNDSAVLSLFQSINGMHPQLLELL 457
N S+E F A+ +A+ ++ G ++ ++ L Q NG + LE+
Sbjct: 90 NFGSKEDANVFASAMMHALEVL-----NSQETGPTLPRQNSQLPA-QVQNGPSQEELEIQ 143
Query: 458 N-QLDERRLYYEGLQDKLAQIRDARGALSALREEH---------REKLRRAAEEAERQRQ 507
QL E++ E +++L + R R L R E +E+L R +E ERQ +
Sbjct: 144 RRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQER 203
Query: 508 IQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPY 567
++ ++LE +QE LE Q +L +R + QE+ER RLE+++Q + + Q+ L +
Sbjct: 204 LERQERLE-----RQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEW 258
Query: 568 AQLQAMPAAGGVLYQPSGPASFPSTFSPAGSVEGSPMHGVYMSQPAPAAGPYPSMPSTAA 627
+ + + +A + PAS +P SV G Q A PS
Sbjct: 259 ERERRISSA-------AAPASVE---TPLNSVLGDSSASEPGLQAASQPAETPSQQGIVL 308
Query: 628 DP-SMVSAYMYPAGATGAQAAPQAQAGPTASPAYSSYQPTPTAGYQNVASQAPQSLPAIS 686
P + P G A A GP P S P P + +Q P P
Sbjct: 309 GPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368
Query: 687 QPPQSSTMGYMGSQS 701
PP ++ ++ S S
Sbjct: 369 APPLPASGFFLASMS 383
Score = 33.1 bits (74), Expect = 1.0
Identities = 43/157 (27%), Positives = 62/157 (39%), Gaps = 19/157 (12%)
Query: 242 LSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTSYPKAEPMPSASSA 301
L +Q +L +R E +E +E Q L + E E +ER RQ+ + E SSA
Sbjct: 210 LERQERL--ERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISSA 267
Query: 302 PPASSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPV----PLTEP 357
+S+ +P+NS + +P L Q ++ + TPS PL P
Sbjct: 268 AAPASV-ETPLNSVLGDSSASEPGL------------QAASQPAETPSQQGIVLGPLAPP 314
Query: 358 AAQPGEGHAAPTNVVENPLPETDSQPIPPSGGPFSEP 394
P A +V P P P PS GP P
Sbjct: 315 PPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPP 351
>gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]
Length = 613
Score = 63.5 bits (153), Expect = 7e-10
Identities = 37/140 (26%), Positives = 68/140 (48%), Gaps = 8/140 (5%)
Query: 5 SGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYA 64
+ + E L+KAT + E DW +I C+ + +A + K+ ALYA
Sbjct: 23 AASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKIQSPQEKEALYA 82
Query: 65 LEVMESVVKNCGQTVHDEVANKQTMEELKDLLKRQ-----VEVNVRNKILYLIQAWAHAF 119
L V+E + +CG+ H EVA + + EL +L + V+ +++ ++ +W F
Sbjct: 83 LTVLEMCMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGSWATGKVKGRVIEILFSWTVWF 142
Query: 120 RNEPKYKVVQDTYQIMKVEG 139
+ K ++D YQ++K +G
Sbjct: 143 PEDIK---IRDAYQMLKKQG 159
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 11/124 (8%)
Query: 169 CRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNRKAEGKAT 228
CR F + R+HHCR CG++ C CS+K + E RVC+ CY N+
Sbjct: 1822 CREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCR-ENPARVCDQCYSYCNK------- 1873
Query: 229 STTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERLRQKSTYTS 288
E P E + S +++ PP + + +E++ L L + EE E +R + Y
Sbjct: 1874 DVPEEPSEKPEALDSSKNESPPYSFVVRVPKADEVEWILDLKE---EENELVRSEFYYEQ 1930
Query: 289 YPKA 292
P A
Sbjct: 1931 APSA 1934
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,593,369
Number of Sequences: 37866
Number of extensions: 1927352
Number of successful extensions: 24817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 376
Number of HSP's successfully gapped in prelim test: 1490
Number of HSP's that attempted gapping in prelim test: 13103
Number of HSP's gapped (non-prelim): 9094
length of query: 777
length of database: 18,247,518
effective HSP length: 110
effective length of query: 667
effective length of database: 14,082,258
effective search space: 9392866086
effective search space used: 9392866086
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.