Guide to the Human Genome
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Search of human proteins with 4758450

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758450 guanine nucleotide binding protein (G protein),
gamma 4 [Homo sapiens]
         (75 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148922937 guanine nucleotide binding protein (G protein), gam...   151   1e-37
gi|148922892 guanine nucleotide binding protein (G protein), gam...   151   1e-37
gi|4758450 guanine nucleotide binding protein (G protein), gamma...   151   1e-37
gi|54114974 guanine nucleotide binding protein (G protein), gamm...   117   2e-27
gi|6912394 guanine nucleotide binding protein (G protein), gamma...   105   6e-24
gi|15147246 guanine nucleotide binding protein (G protein), gamm...    98   1e-21
gi|32698769 guanine nucleotide binding protein (G protein), gamm...    87   2e-18
gi|51036603 G-protein gamma-12 subunit [Homo sapiens]                  87   4e-18
gi|63055067 guanine nucleotide binding protein (G protein), gamm...    64   2e-11
gi|4885287 guanine nucleotide binding protein (G protein), gamma...    64   3e-11
gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens]           58   2e-09
gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens]           58   2e-09
gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens]           58   2e-09
gi|239750840 PREDICTED: hypothetical protein XP_002347578 [Homo ...    54   4e-08
gi|239745202 PREDICTED: hypothetical protein XP_002343408 [Homo ...    54   4e-08
gi|11386179 guanine nucleotide binding protein (G protein), gamm...    48   2e-06
gi|21361097 DNAJC25-GNG10 protein [Homo sapiens]                       45   1e-05
gi|14589849 guanine nucleotide binding protein-gamma transducing...    45   2e-05
gi|4758448 guanine nucleotide binding protein gamma 11 precursor...    44   2e-05
gi|7706567 guanine nucleotide binding protein (G protein), gamma...    38   0.002
gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]         34   0.029
gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]         32   0.14 
gi|20357547 ATPase, H+ transporting, lysosomal 14kD, V1 subunit ...    26   6.1  

>gi|148922937 guanine nucleotide binding protein (G protein),
          gamma 4 [Homo sapiens]
          Length = 75

 Score =  151 bits (381), Expect = 1e-37
 Identities = 75/75 (100%), Positives = 75/75 (100%)

Query: 1  MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 60
          MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA
Sbjct: 1  MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 60

Query: 61 SENPFREKKFFCTIL 75
          SENPFREKKFFCTIL
Sbjct: 61 SENPFREKKFFCTIL 75


>gi|148922892 guanine nucleotide binding protein (G protein),
          gamma 4 [Homo sapiens]
          Length = 75

 Score =  151 bits (381), Expect = 1e-37
 Identities = 75/75 (100%), Positives = 75/75 (100%)

Query: 1  MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 60
          MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA
Sbjct: 1  MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 60

Query: 61 SENPFREKKFFCTIL 75
          SENPFREKKFFCTIL
Sbjct: 61 SENPFREKKFFCTIL 75


>gi|4758450 guanine nucleotide binding protein (G protein), gamma
          4 [Homo sapiens]
          Length = 75

 Score =  151 bits (381), Expect = 1e-37
 Identities = 75/75 (100%), Positives = 75/75 (100%)

Query: 1  MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 60
          MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA
Sbjct: 1  MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 60

Query: 61 SENPFREKKFFCTIL 75
          SENPFREKKFFCTIL
Sbjct: 61 SENPFREKKFFCTIL 75


>gi|54114974 guanine nucleotide binding protein (G protein), gamma
          2 [Homo sapiens]
          Length = 71

 Score =  117 bits (294), Expect = 2e-27
 Identities = 55/71 (77%), Positives = 65/71 (91%)

Query: 5  MSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENP 64
          M++N+T SI+QARK VEQLKMEA +DR+KVS+AAADL+AYCEAH +EDPL+ PVPASENP
Sbjct: 1  MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP 60

Query: 65 FREKKFFCTIL 75
          FREKKFFC IL
Sbjct: 61 FREKKFFCAIL 71


>gi|6912394 guanine nucleotide binding protein (G protein), gamma
          3 [Homo sapiens]
          Length = 75

 Score =  105 bits (263), Expect = 6e-24
 Identities = 52/75 (69%), Positives = 59/75 (78%)

Query: 1  MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPA 60
          MK     NST SI QARK VEQLK+EA + R+KVS+AAADL+ YC+AH  EDPLI PVP 
Sbjct: 1  MKGETPVNSTMSIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT 60

Query: 61 SENPFREKKFFCTIL 75
          SENPFREKKFFC +L
Sbjct: 61 SENPFREKKFFCALL 75


>gi|15147246 guanine nucleotide binding protein (G protein), gamma
          8 [Homo sapiens]
          Length = 70

 Score = 98.2 bits (243), Expect = 1e-21
 Identities = 45/71 (63%), Positives = 59/71 (83%), Gaps = 1/71 (1%)

Query: 5  MSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENP 64
          MSNN    I++ARK VEQLK+E  +DR+KVSQAAA+LLA+CE H ++DPL+ PVPA+ENP
Sbjct: 1  MSNNMA-KIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENP 59

Query: 65 FREKKFFCTIL 75
          FR+K+ FC +L
Sbjct: 60 FRDKRLFCVLL 70


>gi|32698769 guanine nucleotide binding protein (G protein), gamma
          7 [Homo sapiens]
          Length = 68

 Score = 87.4 bits (215), Expect = 2e-18
 Identities = 38/62 (61%), Positives = 55/62 (88%)

Query: 8  NSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFRE 67
          ++T +I+QARK VEQL++EA ++R+KVS+AA+DL++YCE H R DPL++ VPASENPF++
Sbjct: 2  SATNNIAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFKD 61

Query: 68 KK 69
          KK
Sbjct: 62 KK 63


>gi|51036603 G-protein gamma-12 subunit [Homo sapiens]
          Length = 72

 Score = 86.7 bits (213), Expect = 4e-18
 Identities = 39/67 (58%), Positives = 56/67 (83%), Gaps = 1/67 (1%)

Query: 9  STTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68
          ST +I+QAR+ V+QL++EA ++R+KVS+A+ADL++YCE H R DPL+I +P SENPF++K
Sbjct: 7  STNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDK 66

Query: 69 KFFCTIL 75
          K  C IL
Sbjct: 67 K-TCIIL 72


>gi|63055067 guanine nucleotide binding protein (G protein), gamma
          10 [Homo sapiens]
          Length = 68

 Score = 64.3 bits (155), Expect = 2e-11
 Identities = 33/68 (48%), Positives = 47/68 (69%), Gaps = 1/68 (1%)

Query: 8  NSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFRE 67
          +S  S S  ++ VEQLK+EA ++R+KVSQAAA+L  YC  +  +D L++ VPA  NPFRE
Sbjct: 2  SSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFRE 61

Query: 68 KKFFCTIL 75
           +  C +L
Sbjct: 62 PR-SCALL 68


>gi|4885287 guanine nucleotide binding protein (G protein), gamma
          5 [Homo sapiens]
          Length = 68

 Score = 63.5 bits (153), Expect = 3e-11
 Identities = 31/68 (45%), Positives = 49/68 (72%), Gaps = 1/68 (1%)

Query: 8  NSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFRE 67
          + ++S++  +K V+QL++EA ++RVKVSQAAADL  +C  + + DPL+  V +S NPFR 
Sbjct: 2  SGSSSVAAMKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRP 61

Query: 68 KKFFCTIL 75
          +K  C+ L
Sbjct: 62 QK-VCSFL 68


>gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 57.8 bits (138), Expect = 2e-09
 Identities = 29/59 (49%), Positives = 41/59 (69%), Gaps = 3/59 (5%)

Query: 11 TSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKK 69
          + I QA  AVEQL+MEA +D+VK+   AADLL +C    + DP ++ +PA+ N F+EKK
Sbjct: 9  SDIGQALWAVEQLQMEAGIDQVKM---AADLLKFCTEQAKNDPFLVGIPAATNSFKEKK 64


>gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 57.8 bits (138), Expect = 2e-09
 Identities = 29/59 (49%), Positives = 41/59 (69%), Gaps = 3/59 (5%)

Query: 11 TSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKK 69
          + I QA  AVEQL+MEA +D+VK+   AADLL +C    + DP ++ +PA+ N F+EKK
Sbjct: 9  SDIGQALWAVEQLQMEAGIDQVKM---AADLLKFCTEQAKNDPFLVGIPAATNSFKEKK 64


>gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 57.8 bits (138), Expect = 2e-09
 Identities = 29/59 (49%), Positives = 41/59 (69%), Gaps = 3/59 (5%)

Query: 11 TSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKK 69
          + I QA  AVEQL+MEA +D+VK+   AADLL +C    + DP ++ +PA+ N F+EKK
Sbjct: 9  SDIGQALWAVEQLQMEAGIDQVKM---AADLLKFCTEQAKNDPFLVGIPAATNSFKEKK 64


>gi|239750840 PREDICTED: hypothetical protein XP_002347578 [Homo
          sapiens]
          Length = 68

 Score = 53.5 bits (127), Expect = 4e-08
 Identities = 30/68 (44%), Positives = 43/68 (63%), Gaps = 1/68 (1%)

Query: 8  NSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFRE 67
          +S  S S  +  VEQLK+EA ++R+ VSQAAA+L  YC  +  +D L++ V A  NPF E
Sbjct: 2  SSGASASALQCLVEQLKLEAGVERINVSQAAAELQQYCMQNACKDALLVGVLAGSNPFWE 61

Query: 68 KKFFCTIL 75
           +  C +L
Sbjct: 62 PR-SCALL 68


>gi|239745202 PREDICTED: hypothetical protein XP_002343408 [Homo
          sapiens]
          Length = 68

 Score = 53.5 bits (127), Expect = 4e-08
 Identities = 30/68 (44%), Positives = 43/68 (63%), Gaps = 1/68 (1%)

Query: 8  NSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFRE 67
          +S  S S  +  VEQLK+EA ++R+ VSQAAA+L  YC  +  +D L++ V A  NPF E
Sbjct: 2  SSGASASALQCLVEQLKLEAGVERINVSQAAAELQQYCMQNACKDALLVGVLAGSNPFWE 61

Query: 68 KKFFCTIL 75
           +  C +L
Sbjct: 62 PR-SCALL 68


>gi|11386179 guanine nucleotide binding protein (G protein), gamma
          transducing activity polypeptide 1 [Homo sapiens]
          Length = 74

 Score = 47.8 bits (112), Expect = 2e-06
 Identities = 23/64 (35%), Positives = 36/64 (56%)

Query: 11 TSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKF 70
          T   + +  V+QLK E  ++R+ VS+   ++  Y E    EDPL+  +P  +NPF+E K 
Sbjct: 10 TEKDKLKMEVDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPEDKNPFKELKG 69

Query: 71 FCTI 74
           C I
Sbjct: 70 GCVI 73


>gi|21361097 DNAJC25-GNG10 protein [Homo sapiens]
          Length = 153

 Score = 45.4 bits (106), Expect = 1e-05
 Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 1/53 (1%)

Query: 23  LKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL 75
           L +    + +KVSQAAA+L  YC  +  +D L++ VPA  NPFRE +  C +L
Sbjct: 102 LLVATAYETLKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPR-SCALL 153


>gi|14589849 guanine nucleotide binding protein-gamma transducing
          activity polypeptide 2 [Homo sapiens]
          Length = 69

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 20/49 (40%), Positives = 29/49 (59%)

Query: 20 VEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68
          VEQLK E    R+ +S+A  ++  Y EA    DP +  +P  +NPF+EK
Sbjct: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63


>gi|4758448 guanine nucleotide binding protein gamma 11 precursor
          [Homo sapiens]
          Length = 73

 Score = 44.3 bits (103), Expect = 2e-05
 Identities = 20/49 (40%), Positives = 31/49 (63%)

Query: 20 VEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68
          VEQL+ E  + R +VS+ + ++  Y E    EDPL+  +P  +NPF+EK
Sbjct: 19 VEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPEDKNPFKEK 67


>gi|7706567 guanine nucleotide binding protein (G protein), gamma
          13 [Homo sapiens]
          Length = 67

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 22/63 (34%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 13 ISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFC 72
          + Q +K VE LK +    R   S+   +LL + E  + +DP + P     NP+ EK   C
Sbjct: 6  VPQMKKEVESLKYQLAFQREMASKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVEKG-KC 64

Query: 73 TIL 75
          TIL
Sbjct: 65 TIL 67


>gi|31742476 regulator of G-protein signalling 6 [Homo sapiens]
          Length = 472

 Score = 33.9 bits (76), Expect = 0.029
 Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 11  TSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPF 65
           T+    RK +  L  +     +K+S+ A  L+AY E +V  DPLI P   S NP+
Sbjct: 256 TTKEDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPLITPAEPS-NPW 309


>gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]
          Length = 487

 Score = 31.6 bits (70), Expect = 0.14
 Identities = 14/51 (27%), Positives = 31/51 (60%), Gaps = 1/51 (1%)

Query: 15  QARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPF 65
           + ++ ++  +++    R+K+S+ A  LL+Y E ++  DP ++P P   NP+
Sbjct: 257 ELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLP-PDPSNPW 306


>gi|20357547 ATPase, H+ transporting, lysosomal 14kD, V1 subunit F
           [Homo sapiens]
          Length = 119

 Score = 26.2 bits (56), Expect = 6.1
 Identities = 12/60 (20%), Positives = 31/60 (51%), Gaps = 1/60 (1%)

Query: 11  TSISQARKAVEQLKMEACMDRVKVSQAAADLLAYC-EAHVREDPLIIPVPASENPFREKK 69
           T+I++      Q      +  + ++Q  A+++ +  +AH +  P ++ +P+ E+P+   K
Sbjct: 43  TTINEIEDTFRQFLNRDDIGIILINQYIAEMVRHALDAHQQSIPAVLEIPSKEHPYDAAK 102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.128    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,526,985
Number of Sequences: 37866
Number of extensions: 77828
Number of successful extensions: 271
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 246
Number of HSP's gapped (non-prelim): 23
length of query: 75
length of database: 18,247,518
effective HSP length: 47
effective length of query: 28
effective length of database: 16,467,816
effective search space: 461098848
effective search space used: 461098848
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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