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Search of human proteins with 4758356
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758356 flap structure-specific endonuclease 1 [Homo
sapiens]
(380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758356 flap structure-specific endonuclease 1 [Homo sapiens] 752 0.0
gi|194018535 Gen homolog 1, endonuclease [Homo sapiens] 103 2e-22
gi|194018531 Gen homolog 1, endonuclease [Homo sapiens] 103 2e-22
gi|39995071 exonuclease 1 isoform b [Homo sapiens] 102 7e-22
gi|39995069 exonuclease 1 isoform a [Homo sapiens] 102 7e-22
gi|18491016 exonuclease 1 isoform b [Homo sapiens] 102 7e-22
gi|51988900 XPG-complementing protein [Homo sapiens] 74 2e-13
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 32 0.73
gi|122937396 coiled-coil domain containing 150 [Homo sapiens] 32 0.95
gi|21450705 leucine rich repeat containing 45 [Homo sapiens] 32 0.95
gi|19923981 IQ motif containing D [Homo sapiens] 32 0.95
gi|73623035 sperm associated antigen 5 [Homo sapiens] 31 1.6
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] 31 1.6
gi|62460633 RNA-binding motif protein 16 [Homo sapiens] 31 2.1
gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens] 30 2.8
gi|239743387 PREDICTED: actin-related Arp11 [Homo sapiens] 30 3.6
gi|239509084 PREDICTED: actin-related Arp11 [Homo sapiens] 30 3.6
gi|104526627 triadin [Homo sapiens] 30 3.6
gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens] 30 4.7
gi|13376725 coiled-coil domain containing 92 [Homo sapiens] 30 4.7
gi|5453978 protein kinase, cGMP-dependent, type II [Homo sapiens] 29 6.1
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso... 29 6.1
gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso... 29 6.1
gi|239756399 PREDICTED: similar to hCG32587 [Homo sapiens] 29 6.1
gi|239754791 PREDICTED: actin-related Arp11 [Homo sapiens] 29 6.1
gi|169209349 PREDICTED: similar to golgi autoantigen, golgin sub... 29 6.1
gi|169208321 PREDICTED: similar to golgi autoantigen, golgin sub... 29 6.1
gi|213512168 hypothetical protein LOC259308 [Homo sapiens] 29 6.1
gi|187761324 shootin1 isoform a [Homo sapiens] 29 6.1
gi|50511340 shootin1 isoform b [Homo sapiens] 29 6.1
>gi|4758356 flap structure-specific endonuclease 1 [Homo sapiens]
Length = 380
Score = 752 bits (1941), Expect = 0.0
Identities = 380/380 (100%), Positives = 380/380 (100%)
Query: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET
Sbjct: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
Query: 61 TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAE 120
TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAE
Sbjct: 61 TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAE 120
Query: 121 QEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM 180
QEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM
Sbjct: 121 QEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM 180
Query: 181 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRG 240
DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRG
Sbjct: 181 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRG 240
Query: 241 IGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSE 300
IGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSE
Sbjct: 241 IGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSE 300
Query: 301 PNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEP 360
PNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEP
Sbjct: 301 PNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEP 360
Query: 361 KGSTKKKAKTGAAGKFKRGK 380
KGSTKKKAKTGAAGKFKRGK
Sbjct: 361 KGSTKKKAKTGAAGKFKRGK 380
>gi|194018535 Gen homolog 1, endonuclease [Homo sapiens]
Length = 908
Score = 103 bits (258), Expect = 2e-22
Identities = 71/253 (28%), Positives = 127/253 (50%), Gaps = 28/253 (11%)
Query: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
MG+ L +++ V + +++ G+ +A+D S+ + + + G V++
Sbjct: 1 MGVNDLWQILEPVK----QHIPLRNLGGKTIAVDLSLWVCEAQTVKKMMGSVMK------ 50
Query: 61 TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERR-AEAEKQLQQAQAAGA 119
HL +F+R + + +K V+V +G+PP+LK+ ++KR++ R + K Q
Sbjct: 51 -PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSH 109
Query: 120 EQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATED 179
+ V + EC H+L +GIP++ A EAEA CA L G V T D
Sbjct: 110 FKSVLR--------------ECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTND 155
Query: 180 MDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYC-ESI 238
D +G+ + R+ T + K + + +S I +LGL+++ V L ILLG DY + +
Sbjct: 156 GDTFLYGAQTVYRNFTMN-TKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGV 214
Query: 239 RGIGPKRAVDLIQ 251
G+G ++A+ LIQ
Sbjct: 215 PGVGKEQALKLIQ 227
>gi|194018531 Gen homolog 1, endonuclease [Homo sapiens]
Length = 908
Score = 103 bits (258), Expect = 2e-22
Identities = 71/253 (28%), Positives = 127/253 (50%), Gaps = 28/253 (11%)
Query: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
MG+ L +++ V + +++ G+ +A+D S+ + + + G V++
Sbjct: 1 MGVNDLWQILEPVK----QHIPLRNLGGKTIAVDLSLWVCEAQTVKKMMGSVMK------ 50
Query: 61 TSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERR-AEAEKQLQQAQAAGA 119
HL +F+R + + +K V+V +G+PP+LK+ ++KR++ R + K Q
Sbjct: 51 -PHLRNLFFRISYLTQMDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWSQKTGRSH 109
Query: 120 EQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATED 179
+ V + EC H+L +GIP++ A EAEA CA L G V T D
Sbjct: 110 FKSVLR--------------ECLHMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTND 155
Query: 180 MDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYC-ESI 238
D +G+ + R+ T + K + + +S I +LGL+++ V L ILLG DY + +
Sbjct: 156 GDTFLYGAQTVYRNFTMN-TKDPHVDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGV 214
Query: 239 RGIGPKRAVDLIQ 251
G+G ++A+ LIQ
Sbjct: 215 PGVGKEQALKLIQ 227
>gi|39995071 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 102 bits (253), Expect = 7e-22
Identities = 88/301 (29%), Positives = 145/301 (48%), Gaps = 21/301 (6%)
Query: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
MGIQGL + I + + ++ Y G+ VA+D +++ IA + + +GE
Sbjct: 1 MGIQGLLQFIKEASEPI----HVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP 51
Query: 61 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG 118
T +G + + M+ +GIKP+ VFDG P K E ++R R+A K Q +
Sbjct: 52 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK 111
Query: 119 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE 178
+ E FT R + +T + G+ L AP EA+A A L KAG V A TE
Sbjct: 112 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE 170
Query: 179 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES 237
D D L FG V+++ ++ + R L ++ +E+F +CIL G DY S
Sbjct: 171 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS 229
Query: 238 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD 290
+RGIG +A +++ + I ++++++ VPE++++ A+ FL V D
Sbjct: 230 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD 289
Query: 291 P 291
P
Sbjct: 290 P 290
>gi|39995069 exonuclease 1 isoform a [Homo sapiens]
Length = 803
Score = 102 bits (253), Expect = 7e-22
Identities = 88/301 (29%), Positives = 145/301 (48%), Gaps = 21/301 (6%)
Query: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
MGIQGL + I + + ++ Y G+ VA+D +++ IA + + +GE
Sbjct: 1 MGIQGLLQFIKEASEPI----HVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP 51
Query: 61 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG 118
T +G + + M+ +GIKP+ VFDG P K E ++R R+A K Q +
Sbjct: 52 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK 111
Query: 119 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE 178
+ E FT R + +T + G+ L AP EA+A A L KAG V A TE
Sbjct: 112 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE 170
Query: 179 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES 237
D D L FG V+++ ++ + R L ++ +E+F +CIL G DY S
Sbjct: 171 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS 229
Query: 238 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD 290
+RGIG +A +++ + I ++++++ VPE++++ A+ FL V D
Sbjct: 230 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD 289
Query: 291 P 291
P
Sbjct: 290 P 290
>gi|18491016 exonuclease 1 isoform b [Homo sapiens]
Length = 846
Score = 102 bits (253), Expect = 7e-22
Identities = 88/301 (29%), Positives = 145/301 (48%), Gaps = 21/301 (6%)
Query: 1 MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGET 60
MGIQGL + I + + ++ Y G+ VA+D +++ IA + + +GE
Sbjct: 1 MGIQGLLQFIKEASEPI----HVRKYKGQVVAVDTYCWLHKGAIACAE-----KLAKGEP 51
Query: 61 TSHLMGMFYRTIRMM-ENGIKPVYVFDGKP-PQLKSGELAKRSERRAEAEKQLQQAQAAG 118
T +G + + M+ +GIKP+ VFDG P K E ++R R+A K Q +
Sbjct: 52 TDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLKGKQLLREGK 111
Query: 119 AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATE 178
+ E FT R + +T + G+ L AP EA+A A L KAG V A TE
Sbjct: 112 VSEARECFT-RSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNKAGIVQAIITE 170
Query: 179 DMDCLTFG-SPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCES 237
D D L FG V+++ ++ + R L ++ +E+F +CIL G DY S
Sbjct: 171 DSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDV-FTEEKFRYMCILSGCDYLSS 229
Query: 238 IRGIGPKRAVDLIQ--KHKSIEEIVRRLD---PNKYPVPENWLHK--EAHQLFLEPEVLD 290
+RGIG +A +++ + I ++++++ VPE++++ A+ FL V D
Sbjct: 230 LRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFIRANNTFLYQLVFD 289
Query: 291 P 291
P
Sbjct: 290 P 290
>gi|51988900 XPG-complementing protein [Homo sapiens]
Length = 1186
Score = 74.3 bits (181), Expect = 2e-13
Identities = 70/269 (26%), Positives = 119/269 (44%), Gaps = 37/269 (13%)
Query: 106 EAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAA 165
E+ QQ +Q+ E+ VT Q E + LL L GIPY+ AP EAEA CA
Sbjct: 740 ESNLLAQQNSLKAQKQQQERIA---ATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAI 796
Query: 166 LVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFH-LSRILQELGLNQEQFV 224
L + T+D D FG+ RH+ + K E++ +LGL++ + +
Sbjct: 797 LDLTDQTSGTITDDSDIWLFGA----RHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLI 852
Query: 225 DLCILLGSDYCESIRGIGPKRAVDLIQKH--KSIEEIVR--------RLDPNKYPVP-EN 273
+L LLGSDY E I +G A++++ + +E +++ + +P P P +
Sbjct: 853 NLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDT 912
Query: 274 WLHKEAHQLFLEP-------------EVLDPESVELKWSEPNEEELIKFMCGEKQFSEER 320
+ K+ L L P V+D W +P+ +++ +F ++ F R
Sbjct: 913 KVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFC--QRYFGWNR 970
Query: 321 IRSGVKRLSKSRQ---GSTQGRLDDFFKV 346
++ +Q TQ R+D FF++
Sbjct: 971 TKTDESLFPVLKQLDAQQTQLRIDSFFRL 999
Score = 56.6 bits (135), Expect = 4e-08
Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 23/134 (17%)
Query: 1 MGIQGLAKLIA----DVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVR-QGGDVLQN 55
MG+QGL KL+ V+P A+ G+ +A+D S+ + Q L VR + G+ ++N
Sbjct: 1 MGVQGLWKLLECSGRQVSPEALE--------GKILAVDISIWLNQALKGVRDRHGNSIEN 52
Query: 56 EEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQ 115
HL+ +F+R +++ I+P++VFDG P LK L KR +R+ A ++
Sbjct: 53 P------HLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKT- 105
Query: 116 AAGAEQEVEKFTKR 129
E+ ++ F KR
Sbjct: 106 ---TEKLLKTFLKR 116
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 32.3 bits (72), Expect = 0.73
Identities = 26/77 (33%), Positives = 35/77 (45%), Gaps = 5/77 (6%)
Query: 296 LKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKR 355
LK + +E+E K G ++ SE RI L S S D + G + AK+
Sbjct: 182 LKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDAS-----DASGEEGGRVPKAKK 236
Query: 356 KEPEPKGSTKKKAKTGA 372
K P KG KKK K G+
Sbjct: 237 KAPLAKGGRKKKKKKGS 253
>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
Length = 1101
Score = 32.0 bits (71), Expect = 0.95
Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 96 ELAKRSERRA--EAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGI 150
EL +R A + E+ L Q + E EV+++ R++ + QHN E + L +G+
Sbjct: 707 ELGRRDSEIAGLKKERDLNQQRVQKLEAEVDQWQARMLVMEDQHNSEIESLQKALGV 763
>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
Length = 670
Score = 32.0 bits (71), Expect = 0.95
Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 15/146 (10%)
Query: 190 LMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCE-SIRGIGPKRAVD 248
L+R L+A+ K L +Q + + ++ QEQ + S E +R I + +D
Sbjct: 358 LLRDLSAANEKNLLLQN-QVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLD 416
Query: 249 LIQKH-------------KSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVE 295
+ ++ K +E + R L+ ++ + E EA +L LE E+ ++
Sbjct: 417 MEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAA 476
Query: 296 LKWSEPNEEELIKFMCGEKQFSEERI 321
L EEELIK + ++R+
Sbjct: 477 LSERGQAEEELIKAKSQARLEEQQRL 502
>gi|19923981 IQ motif containing D [Homo sapiens]
Length = 347
Score = 32.0 bits (71), Expect = 0.95
Identities = 37/163 (22%), Positives = 66/163 (40%), Gaps = 18/163 (11%)
Query: 194 LTASEAKKL------PIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAV 247
LT EAK++ I + L +L + N+E D+ +LG D ++R V
Sbjct: 44 LTTIEAKRIMSILDEAIYKVELVTLLSYVASNRE---DMEGMLGEDVMRAVREHEDLCQV 100
Query: 248 DLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELI 307
L++ + ++E R+L K E WL + L+ L P ++K S N L+
Sbjct: 101 -LLENVRCLKEKERQLQEQKEAEEEGWLRDRLLSIELQKSSLSPLMQQIKDSTKNVLRLL 159
Query: 308 KFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL 350
S + ++ ++ R Q +D ++ G L
Sbjct: 160 --------LSNPQAARLLQMQTQGRSAEAQNFIDSLIELRGFL 194
>gi|73623035 sperm associated antigen 5 [Homo sapiens]
Length = 1193
Score = 31.2 bits (69), Expect = 1.6
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 257 EEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQF 316
E + +LD N P+ NW+ + +++L EV + L+ E+ +IKF +
Sbjct: 1091 EALAGQLDSNCQPMATNWIQE---KVWLSQEVDKLRVMFLEMKNEKEKLMIKFQ-SHRNI 1146
Query: 317 SEERIRSGVKRLSK 330
EE +R K L K
Sbjct: 1147 LEENLRRSDKELEK 1160
>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
Length = 439
Score = 31.2 bits (69), Expect = 1.6
Identities = 36/131 (27%), Positives = 61/131 (46%), Gaps = 14/131 (10%)
Query: 75 MENGIKPVYVFDGKPPQLKSGELAKRSERRAEA--EKQLQQAQAAGAEQEVEKFTKRLV- 131
ME +KPV++ + + ER AEA +K+L+Q +A +E K+T ++V
Sbjct: 195 MEPRLKPVFI--------RKKDRVTVQEREAEALKQKELEQ-EAKRMAEERRKYTLKIVE 245
Query: 132 KVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVL- 190
+ TK+ +E K L+ + D ++ E A V+ K ED + L +
Sbjct: 246 EETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIE 305
Query: 191 -MRHLTASEAK 200
MR+LT E +
Sbjct: 306 RMRNLTEEERR 316
>gi|62460633 RNA-binding motif protein 16 [Homo sapiens]
Length = 1271
Score = 30.8 bits (68), Expect = 2.1
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 18/116 (15%)
Query: 279 AHQLFLEPEVLDPESVELKWSEPN--------EEEL-------IKFMCGEKQFSEERIRS 323
+ Q FLEPEV +S++++ + + EEE+ + + S R RS
Sbjct: 351 SQQHFLEPEVNLDDSIDIQQQDMDIDEGQDGVEEEVFEQEAKKVAVRSRSRTHSRSRSRS 410
Query: 324 GVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGSTKKKAKTGAAGKFKRG 379
KR S+SR GS R K + S S ++++ S++++A+ + K+G
Sbjct: 411 PRKRRSRSRSGS---RKRKHRKRSRSRSRERKRKSSRSYSSERRAREREKERQKKG 463
>gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens]
Length = 1834
Score = 30.4 bits (67), Expect = 2.8
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 13/116 (11%)
Query: 86 DGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLL 145
+GKP + K E E RAE ++L ++ A E+E E K +K H ++ +++
Sbjct: 796 EGKPWEEKEAE---NCESRAENFQELLRSMWADEEEEAETLLK-----SKDHEEDQENVN 847
Query: 146 SLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKK 201
++ E A+ L++ + A A ED D L GSPV + L + +K
Sbjct: 848 EAE----MEEIYEFAATQRKLLQEERA-AGAGEDADWLEGGSPVSGQLLAGVQVQK 898
>gi|239743387 PREDICTED: actin-related Arp11 [Homo sapiens]
Length = 210
Score = 30.0 bits (66), Expect = 3.6
Identities = 26/123 (21%), Positives = 53/123 (43%), Gaps = 8/123 (6%)
Query: 181 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQEL------GLNQEQFVDLCILLGSDY 234
D +T PV ++ S K +PI ++ +Q+L G+ EQ ++ + Y
Sbjct: 43 DGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKY 102
Query: 235 CESIRGIGPKRAVDLIQKHKSIEEI--VRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPE 292
C I + A + K I++ + ++ K+ + + ++F PE +P+
Sbjct: 103 CYICPDIVKEFAKYDVDPQKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPD 162
Query: 293 SVE 295
S+E
Sbjct: 163 SME 165
>gi|239509084 PREDICTED: actin-related Arp11 [Homo sapiens]
Length = 210
Score = 30.0 bits (66), Expect = 3.6
Identities = 26/123 (21%), Positives = 53/123 (43%), Gaps = 8/123 (6%)
Query: 181 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQEL------GLNQEQFVDLCILLGSDY 234
D +T PV ++ S K +PI ++ +Q+L G+ EQ ++ + Y
Sbjct: 43 DGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKY 102
Query: 235 CESIRGIGPKRAVDLIQKHKSIEEI--VRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPE 292
C I + A + K I++ + ++ K+ + + ++F PE +P+
Sbjct: 103 CYICPDIVKEFAKYDVDPQKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPD 162
Query: 293 SVE 295
S+E
Sbjct: 163 SME 165
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 30.0 bits (66), Expect = 3.6
Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 27/132 (20%)
Query: 252 KHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEE----ELI 307
K K E+ + ++P K P E+ V + V+ K EE +
Sbjct: 393 KGKKQEKKEKHVEPAKSPKKEH-------------SVPSDKQVKAKTERAKEEIGAVSIK 439
Query: 308 KFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSL----SSAKRKEPEPKGS 363
K + G+K+ E+ ++ + + K + G T L D + G +S K KEPE
Sbjct: 440 KAVPGKKE--EKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPE---- 493
Query: 364 TKKKAKTGAAGK 375
TKK K AGK
Sbjct: 494 TKKDEKMSKAGK 505
>gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]
Length = 436
Score = 29.6 bits (65), Expect = 4.7
Identities = 19/83 (22%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 253 HKSIEEIVRRLDPNKYPVP----ENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIK 308
H+ I +++++ +Y + + W+ + LEP LDP+ + + EE +K
Sbjct: 299 HRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVK 358
Query: 309 FMCGEKQFSEERIRSGVKRLSKS 331
+EE IR+ R ++S
Sbjct: 359 STLEHLGITEEHIRNNQGRDARS 381
>gi|13376725 coiled-coil domain containing 92 [Homo sapiens]
Length = 331
Score = 29.6 bits (65), Expect = 4.7
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 11/121 (9%)
Query: 93 KSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVT-------KQHNDECK--- 142
KS EL KR E EA+ ++++ + A +E+E+ + + K++ +E K
Sbjct: 80 KSSELKKRCEE-LEAQLKVKENENAELLKELEQKNAMITVLENTIKEREKKYLEELKAKS 138
Query: 143 HLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKL 202
H L+L+ S + L A K +++ D GSPVL + A KL
Sbjct: 139 HKLTLLSSELEQRASTIAYLTSQLHAAKKKLMSSSGTSDASPSGSPVLASYKPAPPKDKL 198
Query: 203 P 203
P
Sbjct: 199 P 199
>gi|5453978 protein kinase, cGMP-dependent, type II [Homo sapiens]
Length = 762
Score = 29.3 bits (64), Expect = 6.1
Identities = 25/100 (25%), Positives = 45/100 (45%), Gaps = 15/100 (15%)
Query: 75 MENG-IKPVYVFDGKPPQLKSGELA-----------KRSERRAEAEKQLQQAQAAGAEQE 122
M NG +KP + K P SG L +R RR +AE Q ++ ++
Sbjct: 1 MGNGSVKPKH---SKHPDGHSGNLTTDALRNKVTELERELRRKDAEIQEREYHLKELREQ 57
Query: 123 VEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEAS 162
+ K T + ++T++ ++C L L + ++ S +AS
Sbjct: 58 LSKQTVAIAELTEELQNKCIQLNKLQDVVHMQGGSPLQAS 97
>gi|12083581 phosphoinositide-specific phospholipase C beta 1 isoform
a [Homo sapiens]
Length = 1216
Score = 29.3 bits (64), Expect = 6.1
Identities = 44/218 (20%), Positives = 82/218 (37%), Gaps = 28/218 (12%)
Query: 76 ENGIKPVYVFDGKPPQ--LKSGELAKRSERRAEAEKQLQQAQAAGAEQEVE--------- 124
ENG+ KPP L S + A+ E +Q Q +E
Sbjct: 861 ENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFV 920
Query: 125 ----KFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM 180
K K + + K+H+ + L+ Y + ++ AAL K+ K + +
Sbjct: 921 KLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEP 980
Query: 181 DCLTFGSPVLMRHLTASEAKKL-PIQEFHLSRILQELGLNQEQF----------VDLCIL 229
GS + + L A +A+ + + + Q L L QEQ+ + L I
Sbjct: 981 SSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQ 1040
Query: 230 LGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNK 267
+D E + K+ ++ +K K +E+ +++D +
Sbjct: 1041 KLTDVAEECQNNQLKKLKEICEKEK--KELKKKMDKKR 1076
>gi|33356544 phosphoinositide-specific phospholipase C beta 1 isoform
b [Homo sapiens]
Length = 1173
Score = 29.3 bits (64), Expect = 6.1
Identities = 44/218 (20%), Positives = 82/218 (37%), Gaps = 28/218 (12%)
Query: 76 ENGIKPVYVFDGKPPQ--LKSGELAKRSERRAEAEKQLQQAQAAGAEQEVE--------- 124
ENG+ KPP L S + A+ E +Q Q +E
Sbjct: 861 ENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFV 920
Query: 125 ----KFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDM 180
K K + + K+H+ + L+ Y + ++ AAL K+ K + +
Sbjct: 921 KLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYLRRRAALEKSAKKDSKKKSEP 980
Query: 181 DCLTFGSPVLMRHLTASEAKKL-PIQEFHLSRILQELGLNQEQF----------VDLCIL 229
GS + + L A +A+ + + + Q L L QEQ+ + L I
Sbjct: 981 SSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLRQEQYYSEKYQKREHIKLLIQ 1040
Query: 230 LGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNK 267
+D E + K+ ++ +K K +E+ +++D +
Sbjct: 1041 KLTDVAEECQNNQLKKLKEICEKEK--KELKKKMDKKR 1076
>gi|239756399 PREDICTED: similar to hCG32587 [Homo sapiens]
Length = 306
Score = 29.3 bits (64), Expect = 6.1
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 7/48 (14%)
Query: 110 QLQQAQAAG------AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIP 151
QLQQ +A G A QE+++ +RL + T Q N + + +SLM +P
Sbjct: 239 QLQQQEAQGKAVAEMAHQELKETQERL-EATSQQNQQLQSQMSLMALP 285
>gi|239754791 PREDICTED: actin-related Arp11 [Homo sapiens]
Length = 210
Score = 29.3 bits (64), Expect = 6.1
Identities = 26/123 (21%), Positives = 53/123 (43%), Gaps = 8/123 (6%)
Query: 181 DCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQEL------GLNQEQFVDLCILLGSDY 234
D +T PV ++ S K +PI ++ +Q+L G+ EQ ++ + Y
Sbjct: 43 DGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKY 102
Query: 235 CESIRGIGPKRAVDLIQKHKSIEEI--VRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPE 292
C I + A + K I++ + ++ K+ + + ++F PE +P+
Sbjct: 103 CYICPDIVKEFAKYDVDPWKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPD 162
Query: 293 SVE 295
S+E
Sbjct: 163 SME 165
>gi|169209349 PREDICTED: similar to golgi autoantigen, golgin
subfamily a, 2, partial [Homo sapiens]
Length = 97
Score = 29.3 bits (64), Expect = 6.1
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 7/48 (14%)
Query: 110 QLQQAQAAG------AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIP 151
QLQQ +A G A QE+++ +RL + T Q N + + +SLM +P
Sbjct: 30 QLQQQEAQGKAVAEMAHQELKETQERL-EATSQQNQQLQSQMSLMALP 76
>gi|169208321 PREDICTED: similar to golgi autoantigen, golgin
subfamily a, 2, partial [Homo sapiens]
Length = 97
Score = 29.3 bits (64), Expect = 6.1
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 7/48 (14%)
Query: 110 QLQQAQAAG------AEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIP 151
QLQQ +A G A QE+++ +RL + T Q N + + +SLM +P
Sbjct: 30 QLQQQEAQGKAVAEMAHQELKETQERL-EATSQQNQQLQSQMSLMALP 76
>gi|213512168 hypothetical protein LOC259308 [Homo sapiens]
Length = 1335
Score = 29.3 bits (64), Expect = 6.1
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 8/71 (11%)
Query: 90 PQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMG 149
PQLK +L R E+EK LQ +Q K T L T N + + G
Sbjct: 1117 PQLKLPQLPPRVPGEKESEKDLQDSQT--------KLTVILEPATIPENAQTVLPQASQG 1168
Query: 150 IPYLDAPSEAE 160
P+L P++A+
Sbjct: 1169 QPFLSQPTQAK 1179
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 29.3 bits (64), Expect = 6.1
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 7/56 (12%)
Query: 250 IQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEE 305
IQ + ++E+ +L+ LHKE H L + E+L+ + EL+ N EE
Sbjct: 281 IQHQQKVKELEEQLE-------NETLHKEIHNLKQQLELLEEDKKELELKYQNSEE 329
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 29.3 bits (64), Expect = 6.1
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 7/56 (12%)
Query: 250 IQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEE 305
IQ + ++E+ +L+ LHKE H L + E+L+ + EL+ N EE
Sbjct: 281 IQHQQKVKELEEQLE-------NETLHKEIHNLKQQLELLEEDKKELELKYQNSEE 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,087,856
Number of Sequences: 37866
Number of extensions: 632056
Number of successful extensions: 2779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2752
Number of HSP's gapped (non-prelim): 38
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.