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Search of human proteins with 4758260
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758260 eukaryotic translation initiation factor 4E binding
protein 2 [Homo sapiens]
(120 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758260 eukaryotic translation initiation factor 4E binding p... 250 2e-67
gi|4758258 eukaryotic translation initiation factor 4E binding p... 126 3e-30
gi|4503537 eukaryotic translation initiation factor 4E binding p... 113 4e-26
gi|222080070 pleckstrin homology domain-containing family G memb... 29 0.72
gi|222080068 pleckstrin homology domain-containing family G memb... 29 0.72
gi|222080066 pleckstrin homology domain-containing family G memb... 29 0.72
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 29 0.94
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens] 27 3.6
gi|10863935 reticulon 1 isoform A [Homo sapiens] 27 3.6
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 27 4.6
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 27 4.6
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 27 4.6
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 27 4.6
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 27 4.6
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens] 26 6.1
gi|50345831 forkhead box J3 [Homo sapiens] 26 6.1
gi|126032348 hect domain and RLD 2 [Homo sapiens] 26 7.9
gi|239753928 PREDICTED: hypothetical protein [Homo sapiens] 26 7.9
gi|239753012 PREDICTED: similar to hCG2024922 [Homo sapiens] 26 7.9
gi|239747532 PREDICTED: hypothetical protein XP_002347654 [Homo ... 26 7.9
gi|239741408 PREDICTED: hypothetical protein XP_002342164 [Homo ... 26 7.9
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H... 26 7.9
>gi|4758260 eukaryotic translation initiation factor 4E binding
protein 2 [Homo sapiens]
Length = 120
Score = 250 bits (639), Expect = 2e-67
Identities = 120/120 (100%), Positives = 120/120 (100%)
Query: 1 MSSSAGSGHQPSQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLL 60
MSSSAGSGHQPSQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLL
Sbjct: 1 MSSSAGSGHQPSQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLL 60
Query: 61 DRRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI 120
DRRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI
Sbjct: 61 DRRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI 120
>gi|4758258 eukaryotic translation initiation factor 4E binding
protein 1 [Homo sapiens]
Length = 118
Score = 126 bits (317), Expect = 3e-30
Identities = 68/119 (57%), Positives = 85/119 (71%), Gaps = 4/119 (3%)
Query: 4 SAGSGHQPSQSRAIP-TRTVAISDAAQLPH-DYCTTPGGTLFSTTPGGTRIIYDRKFLLD 61
S GS + SRAIP TR V + D QLP DY TTPGGTLFSTTPGGTRIIYDRKFL++
Sbjct: 2 SGGSSCSQTPSRAIPATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLME 61
Query: 62 RRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI 120
RNSP+ +TPP LP IPGVTSP + ++ +E + + N+ + K A G+++QFEMDI
Sbjct: 62 CRNSPVTKTPPRDLPTIPGVTSPSS--DEPPMEASQSHLRNSPEDKRAGGEESQFEMDI 118
>gi|4503537 eukaryotic translation initiation factor 4E binding
protein 3 [Homo sapiens]
Length = 100
Score = 113 bits (282), Expect = 4e-26
Identities = 55/92 (59%), Positives = 67/92 (72%), Gaps = 6/92 (6%)
Query: 29 QLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPMAQTPPCHLPNIPGVTSPGTLI 88
QLP Y TTPGGTL++TTPGGTRIIYDRKFLL+ +NSP+A+TPPC LP IPGVT+P T
Sbjct: 15 QLPDCYSTTPGGTLYATTPGGTRIIYDRKFLLECKNSPIARTPPCCLPQIPGVTTPPT-- 72
Query: 89 EDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI 120
++ L L + + + DDAQFEMDI
Sbjct: 73 ----APLSKLEELKEQETEEEIPDDAQFEMDI 100
>gi|222080070 pleckstrin homology domain-containing family G member
6 isoform b [Homo sapiens]
Length = 758
Score = 29.3 bits (64), Expect = 0.72
Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 3/81 (3%)
Query: 2 SSSAGSGHQPSQSRAIPTRTVAIS---DAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKF 58
S S+ G P S IP V DA +P D + GTL TP G+R R
Sbjct: 518 SQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLR 577
Query: 59 LLDRRNSPMAQTPPCHLPNIP 79
R P L +IP
Sbjct: 578 QRALRRDPRLTFSTLELRDIP 598
>gi|222080068 pleckstrin homology domain-containing family G member
6 isoform a [Homo sapiens]
Length = 790
Score = 29.3 bits (64), Expect = 0.72
Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 3/81 (3%)
Query: 2 SSSAGSGHQPSQSRAIPTRTVAIS---DAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKF 58
S S+ G P S IP V DA +P D + GTL TP G+R R
Sbjct: 550 SQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLR 609
Query: 59 LLDRRNSPMAQTPPCHLPNIP 79
R P L +IP
Sbjct: 610 QRALRRDPRLTFSTLELRDIP 630
>gi|222080066 pleckstrin homology domain-containing family G member
6 isoform a [Homo sapiens]
Length = 790
Score = 29.3 bits (64), Expect = 0.72
Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 3/81 (3%)
Query: 2 SSSAGSGHQPSQSRAIPTRTVAIS---DAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKF 58
S S+ G P S IP V DA +P D + GTL TP G+R R
Sbjct: 550 SQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLR 609
Query: 59 LLDRRNSPMAQTPPCHLPNIP 79
R P L +IP
Sbjct: 610 QRALRRDPRLTFSTLELRDIP 630
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 28.9 bits (63), Expect = 0.94
Identities = 19/79 (24%), Positives = 30/79 (37%)
Query: 11 PSQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPMAQT 70
PS+ R+ A++ A +P TT TP T ++ + SP
Sbjct: 674 PSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSP 733
Query: 71 PPCHLPNIPGVTSPGTLIE 89
PP + P P P ++E
Sbjct: 734 PPSYHPPPPPTKKPEVVVE 752
>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
Length = 455
Score = 26.9 bits (58), Expect = 3.6
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 11/106 (10%)
Query: 9 HQPSQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNS--P 66
H P S P ++ Q+PH G ++ T GG R Y ++ S P
Sbjct: 212 HPPDISPYYP---LSPGTVGQIPHPL-GWQGQPVYPITTGGFRHPYPTALTVNASMSRFP 267
Query: 67 MAQTPPCHLPNIPGVTSPGTLI-----EDSKVEVNNLNNLNNHDRK 107
PP H + G+ P + E S+ +V +L++ + D K
Sbjct: 268 PHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSK 313
>gi|10863935 reticulon 1 isoform A [Homo sapiens]
Length = 776
Score = 26.9 bits (58), Expect = 3.6
Identities = 11/26 (42%), Positives = 16/26 (61%)
Query: 70 TPPCHLPNIPGVTSPGTLIEDSKVEV 95
TP LP++PG+ S G DS +E+
Sbjct: 145 TPGPSLPDVPGIESRGLFSSDSGIEM 170
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 26.6 bits (57), Expect = 4.6
Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 13/109 (11%)
Query: 9 HQPSQSRAIPTRTVAISDAAQLPHDY---CTTPGGTLFSTTPGGTRIIYDRKFLLDRRNS 65
H P S P ++ Q+PH G ++ T GG R Y ++ S
Sbjct: 235 HPPDISPYYP---LSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMS 291
Query: 66 --PMAQTPPCHLPNIPGVTSPGTLI-----EDSKVEVNNLNNLNNHDRK 107
P PP H + G+ P + E S+ +V +L++ + D K
Sbjct: 292 RFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSK 340
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 26.6 bits (57), Expect = 4.6
Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 13/109 (11%)
Query: 9 HQPSQSRAIPTRTVAISDAAQLPHDY---CTTPGGTLFSTTPGGTRIIYDRKFLLDRRNS 65
H P S P ++ Q+PH G ++ T GG R Y ++ S
Sbjct: 212 HPPDISPYYP---LSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMS 268
Query: 66 --PMAQTPPCHLPNIPGVTSPGTLI-----EDSKVEVNNLNNLNNHDRK 107
P PP H + G+ P + E S+ +V +L++ + D K
Sbjct: 269 RFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSK 317
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 26.6 bits (57), Expect = 4.6
Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 13/109 (11%)
Query: 9 HQPSQSRAIPTRTVAISDAAQLPHDY---CTTPGGTLFSTTPGGTRIIYDRKFLLDRRNS 65
H P S P ++ Q+PH G ++ T GG R Y ++ S
Sbjct: 212 HPPDISPYYP---LSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMS 268
Query: 66 --PMAQTPPCHLPNIPGVTSPGTLI-----EDSKVEVNNLNNLNNHDRK 107
P PP H + G+ P + E S+ +V +L++ + D K
Sbjct: 269 RFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSK 317
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 26.6 bits (57), Expect = 4.6
Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 13/109 (11%)
Query: 9 HQPSQSRAIPTRTVAISDAAQLPHDY---CTTPGGTLFSTTPGGTRIIYDRKFLLDRRNS 65
H P S P ++ Q+PH G ++ T GG R Y ++ S
Sbjct: 212 HPPDISPYYP---LSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMS 268
Query: 66 --PMAQTPPCHLPNIPGVTSPGTLI-----EDSKVEVNNLNNLNNHDRK 107
P PP H + G+ P + E S+ +V +L++ + D K
Sbjct: 269 RFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSK 317
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 26.6 bits (57), Expect = 4.6
Identities = 26/109 (23%), Positives = 42/109 (38%), Gaps = 13/109 (11%)
Query: 9 HQPSQSRAIPTRTVAISDAAQLPHDY---CTTPGGTLFSTTPGGTRIIYDRKFLLDRRNS 65
H P S P ++ Q+PH G ++ T GG R Y ++ S
Sbjct: 259 HPPDISPYYP---LSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMS 315
Query: 66 --PMAQTPPCHLPNIPGVTSPGTLI-----EDSKVEVNNLNNLNNHDRK 107
P PP H + G+ P + E S+ +V +L++ + D K
Sbjct: 316 RFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSK 364
>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
Length = 1597
Score = 26.2 bits (56), Expect = 6.1
Identities = 9/25 (36%), Positives = 16/25 (64%)
Query: 62 RRNSPMAQTPPCHLPNIPGVTSPGT 86
R N P+ TP P++P +++PG+
Sbjct: 808 RYNKPLPPTPDLPQPHLPPISAPGS 832
>gi|50345831 forkhead box J3 [Homo sapiens]
Length = 622
Score = 26.2 bits (56), Expect = 6.1
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 14/108 (12%)
Query: 19 TRTVAISDAAQLPHDYCTTPGGTLFSTTPG---GTRIIYDRKFLLDRRNSPMAQTPPCHL 75
T+T I + + + C G + T P GT +Y + R+N P + PP
Sbjct: 517 TQTGLIHSQSNVQQNVCH---GAMHPTKPSQHIGTGNLY----IDSRQNLPPSVMPPPGY 569
Query: 76 PNIP-GVTSPGTLIEDSKVEVNNLNNLNNHD---RKHAVGDDAQFEMD 119
P+IP +++PGT + +N + + + R+ DD Q + D
Sbjct: 570 PHIPQALSTPGTTMAGHHRAMNQQHMMPSQAFQMRRSLPPDDIQDDFD 617
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 25.8 bits (55), Expect = 7.9
Identities = 15/56 (26%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 12 SQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPM 67
SQS + ++ V + + D T+ GT+ G R+ +DR+ +RR+ P+
Sbjct: 3602 SQSGRLSSQPVVVESSHPYTDD--TSTSGTVKIPGAEGLRVEFDRQCSTERRHDPL 3655
>gi|239753928 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1179
Score = 25.8 bits (55), Expect = 7.9
Identities = 10/23 (43%), Positives = 14/23 (60%)
Query: 62 RRNSPMAQTPPCHLPNIPGVTSP 84
RR++P P HLP++P SP
Sbjct: 1007 RRDTPKDTLPMSHLPHVPYTQSP 1029
>gi|239753012 PREDICTED: similar to hCG2024922 [Homo sapiens]
Length = 117
Score = 25.8 bits (55), Expect = 7.9
Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 58 FLLDRRNSPMAQTP---PCHLPNIPGVTSPG 85
FLL ++ A P PC LP P +T+PG
Sbjct: 64 FLLVLQSPACAHLPGWRPCQLPGQPRITAPG 94
>gi|239747532 PREDICTED: hypothetical protein XP_002347654 [Homo
sapiens]
Length = 117
Score = 25.8 bits (55), Expect = 7.9
Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 58 FLLDRRNSPMAQTP---PCHLPNIPGVTSPG 85
FLL ++ A P PC LP P +T+PG
Sbjct: 64 FLLVLQSPACAHLPGWRPCQLPGQPRITAPG 94
>gi|239741408 PREDICTED: hypothetical protein XP_002342164 [Homo
sapiens]
Length = 117
Score = 25.8 bits (55), Expect = 7.9
Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 58 FLLDRRNSPMAQTP---PCHLPNIPGVTSPG 85
FLL ++ A P PC LP P +T+PG
Sbjct: 64 FLLVLQSPACAHLPGWRPCQLPGQPRITAPG 94
>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
sapiens]
Length = 425
Score = 25.8 bits (55), Expect = 7.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 71 PPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLN 102
PP P P +PGTL +++ +N N LN
Sbjct: 390 PPAPAPPAPSAPAPGTLAKEA--AASNTNTLN 419
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,543,630
Number of Sequences: 37866
Number of extensions: 278357
Number of successful extensions: 539
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 529
Number of HSP's gapped (non-prelim): 23
length of query: 120
length of database: 18,247,518
effective HSP length: 89
effective length of query: 31
effective length of database: 14,877,444
effective search space: 461200764
effective search space used: 461200764
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.