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Search of human proteins with 4758138
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo
sapiens]
(614 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 1256 0.0
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 807 0.0
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 802 0.0
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 362 e-100
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 362 e-100
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 360 3e-99
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 343 3e-94
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi... 330 3e-90
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 328 7e-90
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 328 7e-90
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 327 2e-89
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 291 9e-79
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 291 9e-79
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 291 9e-79
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 285 7e-77
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 271 1e-72
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 239 4e-63
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 214 2e-55
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 203 3e-52
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 197 2e-50
gi|13129006 nucleolar protein GU2 [Homo sapiens] 197 2e-50
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 196 7e-50
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 195 1e-49
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 193 3e-49
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 191 2e-48
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 185 9e-47
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 185 9e-47
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 180 4e-45
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 176 6e-44
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ... 175 1e-43
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 1256 bits (3251), Expect = 0.0
Identities = 614/614 (100%), Positives = 614/614 (100%)
Query: 1 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 60
MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ
Sbjct: 1 MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 60
Query: 61 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 120
EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI
Sbjct: 61 EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 120
Query: 121 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 180
QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA
Sbjct: 121 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 180
Query: 181 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 240
QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR
Sbjct: 181 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 240
Query: 241 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 300
RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI
Sbjct: 241 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 300
Query: 301 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 360
NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK
Sbjct: 301 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 360
Query: 361 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 420
MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN
Sbjct: 361 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 420
Query: 421 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 480
SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS
Sbjct: 421 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 480
Query: 481 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 540
GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY
Sbjct: 481 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 540
Query: 541 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 600
TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA
Sbjct: 541 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 600
Query: 601 APMIGYPMPTGYSQ 614
APMIGYPMPTGYSQ
Sbjct: 601 APMIGYPMPTGYSQ 614
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 807 bits (2085), Expect = 0.0
Identities = 435/645 (67%), Positives = 482/645 (74%), Gaps = 45/645 (6%)
Query: 3 GYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEH 62
G DRDR RDRG FG G L KKFGNPGE+L KKKW+L ELPKFEKNFY EH
Sbjct: 83 GGFGDRDRDRDRG----GFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEH 138
Query: 63 PDLARRTAQEVETYRRSKEITVRGHN-CPKPVLNFYEANFPANVMDVIARQNFTEPTAIQ 121
P++AR T EV+ RR KEITVRG + CPKPV F+ ANFP VMDV+ Q+FTEPT IQ
Sbjct: 139 PEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQ 198
Query: 122 AQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQ 181
QG+P+ALSG DMVG+AQTGSGKTL+YLLPAIVHINHQP+LERGDGPICLVLAPTRELAQ
Sbjct: 199 CQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQ 258
Query: 182 QVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRR 241
QVQQVA +Y + RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE GKTNLRR
Sbjct: 259 QVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRR 318
Query: 242 TTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHIN 301
TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFL+DY IN
Sbjct: 319 CTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQIN 378
Query: 302 IGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM 361
+G LELSANHNILQIVDVC + EKD KLI+LMEEIM+EKENKTI+FVETKRRCD+LTR+M
Sbjct: 379 VGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRM 438
Query: 362 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 421
RRDGWPAM IHGDKSQ ERDWVLNEF+ GKAPILIATDVASRGLDVEDVKFVINYDYPNS
Sbjct: 439 RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS 498
Query: 422 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSG 481
SEDY+HRIGRTARST GTAYTFFTP N+KQ +LI VL EANQAINPKL+QLV+ RG G
Sbjct: 499 SEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGG 558
Query: 482 RSRGRGG---------------MKDDRRDRYSAGKRGGFN----TFRDRENYDR------ 516
G+GG M D DR G + G ++RDR DR
Sbjct: 559 GGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANG 618
Query: 517 -GYSSLLKRDFGAKT-----QNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNG 570
GY S FGA+ G Y AA Y S+ + AG ++ + T T ++
Sbjct: 619 SGYGS-PNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG---TYGASSTTSTGRSS 674
Query: 571 YDSTQQY---GSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGY 612
S+QQ+ G + M+QQ +A P A MIGY T Y
Sbjct: 675 QSSSQQFSGIGRSGQQPQPLMSQQ-FAQP-PGATNMIGYMGQTAY 717
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 802 bits (2072), Expect = 0.0
Identities = 436/643 (67%), Positives = 482/643 (74%), Gaps = 43/643 (6%)
Query: 3 GYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEH 62
G DRDR RDRG FG G L KKFGNPGE+L KKKW+L ELPKFEKNFY EH
Sbjct: 83 GGFGDRDRDRDRG----GFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEH 138
Query: 63 PDLARRTAQEVETYRRSKEITVRGHN-CPKPVLNFYEANFPANVMDVIARQNFTEPTAIQ 121
P++AR T EV+ RR KEITVRG + CPKPV F+ ANFP VMDV+ Q+FTEPT IQ
Sbjct: 139 PEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQ 198
Query: 122 AQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQ 181
QG+P+ALSG DMVG+AQTGSGKTL+YLLPAIVHINHQP+LERGDGPICLVLAPTRELAQ
Sbjct: 199 CQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQ 258
Query: 182 QVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRR 241
QVQQVA +Y + RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE GKTNLRR
Sbjct: 259 QVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRR 318
Query: 242 TTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHIN 301
TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFL+DY IN
Sbjct: 319 CTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQIN 378
Query: 302 IGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM 361
+G LELSANHNILQIVDVC + EKD KLI+LMEEIM+EKENKTI+FVETKRRCD+LTR+M
Sbjct: 379 VGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRM 438
Query: 362 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 421
RRDGWPAM IHGDKSQ ERDWVLNEF+ GKAPILIATDVASRGLDVEDVKFVINYDYPNS
Sbjct: 439 RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS 498
Query: 422 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDR--- 478
SEDY+HRIGRTARST GTAYTFFTP N+KQ +LI VL EANQAINPKL+QLV+ R
Sbjct: 499 SEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGG 558
Query: 479 --GSGRSRGR--------GGMKDDRRDRYSAGKRGGFN----TFRDRENYDR-------G 517
G GRSR R M D DR G + G ++RDR DR G
Sbjct: 559 GGGGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSG 618
Query: 518 YSSLLKRDFGAKT-----QNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYD 572
Y S FGA+ G Y AA Y S+ + AG ++ + T T ++
Sbjct: 619 YGS-PNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG---TYGASSTTSTGRSSQS 674
Query: 573 STQQY---GSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGY 612
S+QQ+ G + M+QQ +A P A MIGY T Y
Sbjct: 675 SSQQFSGIGRSGQQPQPLMSQQ-FAQP-PGATNMIGYMGQTAY 715
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 362 bits (929), Expect = e-100
Identities = 213/552 (38%), Positives = 311/552 (56%), Gaps = 37/552 (6%)
Query: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109
+ P FEKNFY EH ++ T Q++ R + V G P+P +F F +M I
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQI 268
Query: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169
+ +T+PT IQ QG PVALSG DM+G+A+TGSGKT +++ P ++HI Q LE GDGPI
Sbjct: 269 RKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPI 328
Query: 170 CLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLI 229
+++ PTREL QQ+ + +A L+S +YGG Q + L+ G EI + TPGRLI
Sbjct: 329 AVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLI 388
Query: 230 DFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289
D ++ TNL+R +YLV DEADRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +L
Sbjct: 389 DHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKL 448
Query: 290 AEDFLKDYIHINIGALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFV 348
A D L D I + G + AN ++ QIV++ H K L R + E S ++FV
Sbjct: 449 ARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFV 505
Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
K +EL ++++G +HGD Q ER+ V+++FK P+L+ATDVA+RGLD+
Sbjct: 506 TKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIP 565
Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAIN 468
+K VINYD + + HRIGRT R+ + G AYT TP + DL+ L ANQ ++
Sbjct: 566 SIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVS 625
Query: 469 PKLLQL-VEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLL 522
+LL L +++ +SR +GG + + + G GG +R+R EN DRG ++++
Sbjct: 626 KELLDLAMQNAWFRKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVM 679
Query: 523 KRDFGAKTQNGV-------------------YSAANYTNGSFGSNFVSAGIQTSFRTGN- 562
K G + AA+ +N GS+ A TS + N
Sbjct: 680 SNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNS 739
Query: 563 -PTGTYQNGYDS 573
PT + Q G++S
Sbjct: 740 VPTNSAQQGHNS 751
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 362 bits (929), Expect = e-100
Identities = 213/552 (38%), Positives = 311/552 (56%), Gaps = 37/552 (6%)
Query: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109
+ P FEKNFY EH ++ T Q++ R + V G P+P +F F +M I
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQI 268
Query: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169
+ +T+PT IQ QG PVALSG DM+G+A+TGSGKT +++ P ++HI Q LE GDGPI
Sbjct: 269 RKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPI 328
Query: 170 CLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLI 229
+++ PTREL QQ+ + +A L+S +YGG Q + L+ G EI + TPGRLI
Sbjct: 329 AVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLI 388
Query: 230 DFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289
D ++ TNL+R +YLV DEADRM DMGFE Q+R I +RPDRQTL++SAT+ K++ +L
Sbjct: 389 DHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKL 448
Query: 290 AEDFLKDYIHINIGALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFV 348
A D L D I + G + AN ++ QIV++ H K L R + E S ++FV
Sbjct: 449 ARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFV 505
Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
K +EL ++++G +HGD Q ER+ V+++FK P+L+ATDVA+RGLD+
Sbjct: 506 TKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIP 565
Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAIN 468
+K VINYD + + HRIGRT R+ + G AYT TP + DL+ L ANQ ++
Sbjct: 566 SIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVS 625
Query: 469 PKLLQL-VEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLL 522
+LL L +++ +SR +GG + + + G GG +R+R EN DRG ++++
Sbjct: 626 KELLDLAMQNAWFRKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVM 679
Query: 523 KRDFGAKTQNGV-------------------YSAANYTNGSFGSNFVSAGIQTSFRTGN- 562
K G + AA+ +N GS+ A TS + N
Sbjct: 680 SNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNS 739
Query: 563 -PTGTYQNGYDS 573
PT + Q G++S
Sbjct: 740 VPTNSAQQGHNS 751
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 360 bits (923), Expect = 3e-99
Identities = 179/433 (41%), Positives = 270/433 (62%), Gaps = 9/433 (2%)
Query: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKE-ITVRGHNCPKPVLNFYEANFPANVMDV 108
E F KNFY E P+LA+ + +EV +R E ITV+G CPKP+ ++ + +++
Sbjct: 327 EYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNS 386
Query: 109 IARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGP 168
+ + + +PT IQ Q P +SG D++G+A+TGSGKT+++LLP HI Q LE G+GP
Sbjct: 387 LKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGP 446
Query: 169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
I +++ PTRELA Q+ + ++ + L+ C+YGG QI +L+RG EI + TPGR+
Sbjct: 447 IAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRM 506
Query: 229 IDFLECGK---TNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKE 285
ID L TNLRR TY+VLDEADRM DMGFEPQ+ +IVD +RPDRQT+M+SAT+P+
Sbjct: 507 IDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRA 566
Query: 286 VRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKEN-KT 344
+ LA L I + +G + + Q++ +E+++K ++L+E + +E+
Sbjct: 567 MEALARRILSKPIEVQVGGRSVVCSDVEQQVI----VIEEEKKFLKLLELLGHYQESGSV 622
Query: 345 IVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404
I+FV+ + D L + + R +P M +HG Q +RD ++N+FK+G +L+AT VA+RG
Sbjct: 623 IIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARG 682
Query: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464
LDV+ + V+NY PN EDY+HR GRT R+ G AYTF T + + D+I L +
Sbjct: 683 LDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG 742
Query: 465 QAINPKLLQLVED 477
A+ P L +L D
Sbjct: 743 TAVPPDLEKLWSD 755
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 343 bits (880), Expect = 3e-94
Identities = 195/449 (43%), Positives = 277/449 (61%), Gaps = 16/449 (3%)
Query: 38 GEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSK-EITV------RGHNCP 90
G K K KW +LP +KNFY+E + + E +++R+ IT P
Sbjct: 180 GLKWQKTKWA--DLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIP 237
Query: 91 KPVLNFYEAN--FPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSY 148
P F +A +P VM+ I + F +PT IQ+Q WP+ L G+D++GVAQTG+GKTL Y
Sbjct: 238 NPTCTFDDAFQCYP-EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296
Query: 149 LLPAIVHINHQPFLE-RGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPK 207
L+P +H+ QP L+ + + P LVL PTRELA QV+ +Y L+S C+YGG +
Sbjct: 297 LMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNR 355
Query: 208 GPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVD 267
QI +L++GV+I IATPGRL D NL+ TYLVLDEAD+MLDMGFEPQI KI+
Sbjct: 356 DEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILL 415
Query: 268 QIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDE 327
+RPDRQT+M SATWP V +LA+ +LK+ + + +G L+L A ++ Q + V + EK
Sbjct: 416 DVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475
Query: 328 KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEF 387
+ ++ + S +K IVFV K D L+ + +HGD+ Q++R+ L F
Sbjct: 476 HMQTFLQSMSS--TDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENF 533
Query: 388 KHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTP 447
K GK ILIATD+ASRGLDV DV V N+D+P + E+Y+HRIGRT R+ +TG + T T
Sbjct: 534 KTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTR 593
Query: 448 NNIKQVSDLISVLREANQAINPKLLQLVE 476
N+ + S+LI++L ANQ+I +L+ + E
Sbjct: 594 NDWRVASELINILERANQSIPEELVSMAE 622
>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
sapiens]
Length = 631
Score = 330 bits (845), Expect = 3e-90
Identities = 191/444 (43%), Positives = 265/444 (59%), Gaps = 16/444 (3%)
Query: 43 KKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSK-EITV------RGHNCPKPVLN 95
K+KW +LP +KNFY E + + +V +R+ IT PKP
Sbjct: 165 KRKWA--DLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCR 222
Query: 96 FYEA--NFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI 153
F +A +P +++ I R +PT IQ+Q WP+ L G+D++ VAQTG+GKTLSYL+P
Sbjct: 223 FKDAFQQYP-DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF 281
Query: 154 VHINHQPFL-ERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIR 212
+H++ QP E+ +GP LVL PTRELA V+ ++Y LKS CIYGG + QI
Sbjct: 282 IHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIE 340
Query: 213 DLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPD 272
D+ +GV+I IATPGRL D NLR TYLV+DEAD+MLDM FEPQIRKI+ +RPD
Sbjct: 341 DISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPD 400
Query: 273 RQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRL 332
RQT+M SATWP VRQLA +LKD + + +G L L A + + Q + V + EK L +
Sbjct: 401 RQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQE 459
Query: 333 MEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKA 392
E MS + K I+FV K D+L+ G A +HG+ Q +++ + +FK G
Sbjct: 460 FVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518
Query: 393 PILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQ 452
ILI TD+ SRGLD+ DV V NYD+P + + Y+HR+G R+ KTGT+ T T + K
Sbjct: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578
Query: 453 VSDLISVLREANQAINPKLLQLVE 476
+LI +L ANQ++ L+ + E
Sbjct: 579 AGELIKILDRANQSVPEDLVVMAE 602
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 328 bits (842), Expect = 7e-90
Identities = 223/589 (37%), Positives = 313/589 (53%), Gaps = 52/589 (8%)
Query: 3 GYSSDR---DRGR--DRGFGAPRFGGSRAGPLSGKKFGNPG-----EKLVKKKWNLDELP 52
GY S+R RGR DRG G+R P G+ F G +K V+ W+ LP
Sbjct: 82 GYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGR-FERSGHSRWCDKSVEDDWS-KPLP 139
Query: 53 KFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQ 112
E+ ++ T E Y + G NCP + NF + + +M I
Sbjct: 140 PSER--LEQELFSGGNTGINFEKYD-DIPVEATGSNCPPHIENFSDIDMGEIIMGNIELT 196
Query: 113 NFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI-------------NHQ 159
+T PT +Q P+ D++ AQTGSGKT ++LLP + I +
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
Query: 160 PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVE 219
+ R PI LVLAPTRELA Q+ + A ++ R++ +YGGA G QIRDLERG
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCH 316
Query: 220 ICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----RPDRQT 275
+ +ATPGRL+D +E GK L YLVLDEADRMLDMGFEPQIR+IV+Q + R T
Sbjct: 317 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHT 376
Query: 276 LMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEE 335
+M+SAT+PKE++ LA DFL +YI + +G + S + NI Q V D++K L+ ++
Sbjct: 377 MMFSATFPKEIQMLARDFLDEYIFLAVGRVG-STSENITQKVVWVEDLDKRSFLLDILGA 435
Query: 336 IMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPIL 395
S+ + T+VFVETK+ D L + +G+ IHGD+SQ++R+ L++F+ GK+PIL
Sbjct: 436 TGSD--SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPIL 493
Query: 396 IATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSD 455
+AT VA+RGLD+ +V+ VIN+D P+ E+Y+HRIGRT R G A +FF N+ D
Sbjct: 494 VATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKD 553
Query: 456 LISVLREANQAINPKLLQLV-EDRGSGRSRGRG---------GMKDDRRDRYSAGKRGGF 505
L+ +L EA Q + L + E G SRGR G +D R+ S GF
Sbjct: 554 LLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQS--SGSSSSGF 611
Query: 506 NTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGI 554
R + G R FG G Y++ Y G N+ S G+
Sbjct: 612 GASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGY-----GGNYNSQGV 655
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 328 bits (842), Expect = 7e-90
Identities = 223/589 (37%), Positives = 313/589 (53%), Gaps = 52/589 (8%)
Query: 3 GYSSDR---DRGR--DRGFGAPRFGGSRAGPLSGKKFGNPG-----EKLVKKKWNLDELP 52
GY S+R RGR DRG G+R P G+ F G +K V+ W+ LP
Sbjct: 82 GYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGR-FERSGHSRWCDKSVEDDWS-KPLP 139
Query: 53 KFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQ 112
E+ ++ T E Y + G NCP + NF + + +M I
Sbjct: 140 PSER--LEQELFSGGNTGINFEKYD-DIPVEATGSNCPPHIENFSDIDMGEIIMGNIELT 196
Query: 113 NFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI-------------NHQ 159
+T PT +Q P+ D++ AQTGSGKT ++LLP + I +
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256
Query: 160 PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVE 219
+ R PI LVLAPTRELA Q+ + A ++ R++ +YGGA G QIRDLERG
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCH 316
Query: 220 ICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----RPDRQT 275
+ +ATPGRL+D +E GK L YLVLDEADRMLDMGFEPQIR+IV+Q + R T
Sbjct: 317 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHT 376
Query: 276 LMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEE 335
+M+SAT+PKE++ LA DFL +YI + +G + S + NI Q V D++K L+ ++
Sbjct: 377 MMFSATFPKEIQMLARDFLDEYIFLAVGRVG-STSENITQKVVWVEDLDKRSFLLDILGA 435
Query: 336 IMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPIL 395
S+ + T+VFVETK+ D L + +G+ IHGD+SQ++R+ L++F+ GK+PIL
Sbjct: 436 TGSD--SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPIL 493
Query: 396 IATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSD 455
+AT VA+RGLD+ +V+ VIN+D P+ E+Y+HRIGRT R G A +FF N+ D
Sbjct: 494 VATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKD 553
Query: 456 LISVLREANQAINPKLLQLV-EDRGSGRSRGRG---------GMKDDRRDRYSAGKRGGF 505
L+ +L EA Q + L + E G SRGR G +D R+ S GF
Sbjct: 554 LLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQS--SGSSSSGF 611
Query: 506 NTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGI 554
R + G R FG G Y++ Y G N+ S G+
Sbjct: 612 GASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGY-----GGNYNSQGV 655
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 327 bits (839), Expect = 2e-89
Identities = 198/500 (39%), Positives = 280/500 (56%), Gaps = 37/500 (7%)
Query: 82 ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
+ G+NCP + +F + +M I +T PT +Q P+ D++ AQTG
Sbjct: 168 VEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 227
Query: 142 SGKTLSYLLPAIVHI-------------NHQPFLERGDGPICLVLAPTRELAQQVQQVAA 188
SGKT ++LLP + I + + R PI LVLAPTRELA Q+ + A
Sbjct: 228 SGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEAR 287
Query: 189 EYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLD 248
++ R++ +YGGA G QIRDLERG + +ATPGRL+D +E GK L YLVLD
Sbjct: 288 KFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 347
Query: 249 EADRMLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGA 304
EADRMLDMGFEPQIR+IV+Q + R T+M+SAT+PKE++ LA DFL +YI + +G
Sbjct: 348 EADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 407
Query: 305 LELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRD 364
+ S + NI Q V + +K L+ L+ + K++ T+VFVETK+ D L + +
Sbjct: 408 VG-STSENITQKVVWVEESDKRSFLLDLLNA--TGKDSLTLVFVETKKGADSLEDFLYHE 464
Query: 365 GWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSED 424
G+ IHGD+SQ++R+ L++F+ GK+PIL+AT VA+RGLD+ +VK VIN+D P+ E+
Sbjct: 465 GYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEE 524
Query: 425 YIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLV-EDRGSGRS 483
Y+HRIGRT R G A +FF NI DL+ +L EA Q + L + E G S
Sbjct: 525 YVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS 584
Query: 484 RGRG---------GMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGV 534
RGR G +D R+ S F++ R + G R FG G
Sbjct: 585 RGRSKSSRFSGGFGARDYRQS--SGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGF 642
Query: 535 YSAANYTNGSFGSNFVSAGI 554
Y++ Y G N+ S G+
Sbjct: 643 YNSDGY-----GGNYNSQGV 657
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 291 bits (746), Expect = 9e-79
Identities = 171/455 (37%), Positives = 267/455 (58%), Gaps = 27/455 (5%)
Query: 82 ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
+ V GH+ P +L F EAN + + IA+ +T+ T +Q P+ L+G D++ AQTG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
Query: 142 SGKTLSYLLPAIVHINHQPF----LERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLK 197
SGKT ++LLP + H+ H + P C+++APTREL Q+ A ++ ++
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVR 395
Query: 198 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257
+ IYGG G IR + +G I ATPGRL+D + K L++ YLVLDEADRMLDMG
Sbjct: 396 AVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMG 455
Query: 258 FEPQIRKIVD----QIRPDRQTLMWSATWPKEVRQLAEDFLK-DYIHINIGALELSANHN 312
F P+++K++ + RQTLM+SAT+P+E+++LA +FLK +Y+ + +G + A +
Sbjct: 456 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRD 514
Query: 313 ILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIH 372
+ Q V K EKL+ ++ I E+ T+VFVETK++ D + + ++ IH
Sbjct: 515 VQQTVLQVGQFSKREKLVEILRNIGDER---TMVFVETKKKADFIATFLCQEKISTTSIH 571
Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
GD+ Q+ER+ L +F+ GK P+L+AT VA+RGLD+E+V+ VIN+D P++ ++Y+HRIGRT
Sbjct: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631
Query: 433 ARSTKTGTAYTFF---TPNNIKQVSDLISVLREANQAINPKLLQLVEDR----GSGRSRG 485
R TG A +FF + N++ Q L+ VL +A Q + L ++ SG +RG
Sbjct: 632 GRCGNTGRAISFFDLESDNHLAQ--PLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRG 689
Query: 486 RGGMKDDRRDRYSAGKRGGFNTFR-----DRENYD 515
D R S GF++ + D E++D
Sbjct: 690 NVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD 724
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 291 bits (746), Expect = 9e-79
Identities = 171/455 (37%), Positives = 267/455 (58%), Gaps = 27/455 (5%)
Query: 82 ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
+ V GH+ P +L F EAN + + IA+ +T+ T +Q P+ L+G D++ AQTG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335
Query: 142 SGKTLSYLLPAIVHINHQPF----LERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLK 197
SGKT ++LLP + H+ H + P C+++APTREL Q+ A ++ ++
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVR 395
Query: 198 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257
+ IYGG G IR + +G I ATPGRL+D + K L++ YLVLDEADRMLDMG
Sbjct: 396 AVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMG 455
Query: 258 FEPQIRKIVD----QIRPDRQTLMWSATWPKEVRQLAEDFLK-DYIHINIGALELSANHN 312
F P+++K++ + RQTLM+SAT+P+E+++LA +FLK +Y+ + +G + A +
Sbjct: 456 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRD 514
Query: 313 ILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIH 372
+ Q V K EKL+ ++ I E+ T+VFVETK++ D + + ++ IH
Sbjct: 515 VQQTVLQVGQFSKREKLVEILRNIGDER---TMVFVETKKKADFIATFLCQEKISTTSIH 571
Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
GD+ Q+ER+ L +F+ GK P+L+AT VA+RGLD+E+V+ VIN+D P++ ++Y+HRIGRT
Sbjct: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631
Query: 433 ARSTKTGTAYTFF---TPNNIKQVSDLISVLREANQAINPKLLQLVEDR----GSGRSRG 485
R TG A +FF + N++ Q L+ VL +A Q + L ++ SG +RG
Sbjct: 632 GRCGNTGRAISFFDLESDNHLAQ--PLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRG 689
Query: 486 RGGMKDDRRDRYSAGKRGGFNTFR-----DRENYD 515
D R S GF++ + D E++D
Sbjct: 690 NVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD 724
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 291 bits (746), Expect = 9e-79
Identities = 171/455 (37%), Positives = 267/455 (58%), Gaps = 27/455 (5%)
Query: 82 ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
+ V GH+ P +L F EAN + + IA+ +T+ T +Q P+ L+G D++ AQTG
Sbjct: 242 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 301
Query: 142 SGKTLSYLLPAIVHINHQPF----LERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLK 197
SGKT ++LLP + H+ H + P C+++APTREL Q+ A ++ ++
Sbjct: 302 SGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVR 361
Query: 198 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257
+ IYGG G IR + +G I ATPGRL+D + K L++ YLVLDEADRMLDMG
Sbjct: 362 AVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMG 421
Query: 258 FEPQIRKIVD----QIRPDRQTLMWSATWPKEVRQLAEDFLK-DYIHINIGALELSANHN 312
F P+++K++ + RQTLM+SAT+P+E+++LA +FLK +Y+ + +G + A +
Sbjct: 422 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRD 480
Query: 313 ILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIH 372
+ Q V K EKL+ ++ I E+ T+VFVETK++ D + + ++ IH
Sbjct: 481 VQQTVLQVGQFSKREKLVEILRNIGDER---TMVFVETKKKADFIATFLCQEKISTTSIH 537
Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
GD+ Q+ER+ L +F+ GK P+L+AT VA+RGLD+E+V+ VIN+D P++ ++Y+HRIGRT
Sbjct: 538 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 597
Query: 433 ARSTKTGTAYTFF---TPNNIKQVSDLISVLREANQAINPKLLQLVEDR----GSGRSRG 485
R TG A +FF + N++ Q L+ VL +A Q + L ++ SG +RG
Sbjct: 598 GRCGNTGRAISFFDLESDNHLAQ--PLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRG 655
Query: 486 RGGMKDDRRDRYSAGKRGGFNTFR-----DRENYD 515
D R S GF++ + D E++D
Sbjct: 656 NVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD 690
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 285 bits (730), Expect = 7e-77
Identities = 163/455 (35%), Positives = 261/455 (57%), Gaps = 43/455 (9%)
Query: 39 EKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYE 98
+K K++W+ ++++ Q+ D T ++ +R IT +G P P+ ++ +
Sbjct: 345 KKEAKQRWD-------DRHWSQKKLD--EMTDRDWRIFREDYSITTKGGKIPNPIRSWKD 395
Query: 99 ANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINH 158
++ P ++++VI + + EPT IQ Q P+ L D++GVA+TGSGKT ++L+P +V I
Sbjct: 396 SSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITT 455
Query: 159 QPFLER----GDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDL 214
P ++R GP ++LAPTRELAQQ+++ ++ + +++ + GG + Q L
Sbjct: 456 LPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRL 515
Query: 215 ERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----- 269
G EI IATPGRLID LE L R TY+VLDEADRM+DMGFEP ++KI++ +
Sbjct: 516 RMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQ 575
Query: 270 RPD---------------------RQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELS 308
+PD RQT+M++AT P V +LA +L+ + IG+
Sbjct: 576 KPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAG-K 634
Query: 309 ANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPA 368
+ + Q V + + EK +KL+ ++E+ + I+FV K+ CD L + + + G+ A
Sbjct: 635 PHERVEQKVFLMSESEKRKKLLAILEQGF---DPPIIIFVNQKKGCDVLAKSLEKMGYNA 691
Query: 369 MGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHR 428
+HG K Q++R++ L+ K G IL+ATDVA RG+D++DV V+NYD + EDYIHR
Sbjct: 692 CTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHR 751
Query: 429 IGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463
IGRT R+ K+G A TF T + +L + E+
Sbjct: 752 IGRTGRAGKSGVAITFLTKEDSAVFYELKQAILES 786
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 271 bits (694), Expect = 1e-72
Identities = 159/409 (38%), Positives = 228/409 (55%), Gaps = 17/409 (4%)
Query: 74 ETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLD 133
E R+ I V G P P+ +F E FPA ++ + ++ PT IQ QG P LSG D
Sbjct: 161 ERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRD 220
Query: 134 MVGVAQTGSGKTLSYLLPAIVHINHQ----PFLERGDGPICLVLAPTRELAQQVQQVAAE 189
M+G+A TGSGKTL + LP I+ Q PF +R +GP L++ P+RELA+Q +
Sbjct: 221 MIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKR-EGPYGLIICPSRELARQTHGILEY 279
Query: 190 YCRACR------LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTT 243
YCR + L+ GG Q+ + GV + +ATPGRL+D L+ +L
Sbjct: 280 YCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICR 339
Query: 244 YLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIG 303
YL LDEADRM+DMGFE IR I + RQTL++SAT PK+++ A+ L + IN+G
Sbjct: 340 YLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 399
Query: 304 ALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRR 363
++ L ++ V+++ K++ L+E + + ++F E K D + +
Sbjct: 400 RAGAAS----LDVIQEVEYVKEEAKMVYLLE-CLQKTPPPVLIFAEKKADVDAIHEYLLL 454
Query: 364 DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSE 423
G A+ IHG K Q+ER + F+ GK +L+ATDVAS+GLD ++ VINYD P E
Sbjct: 455 KGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIE 514
Query: 424 DYIHRIGRTARSTKTGTAYTFFTPNNIKQV-SDLISVLREANQAINPKL 471
+Y+HRIGRT RS TG A TF + V DL ++L EA Q + P L
Sbjct: 515 NYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVL 563
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 239 bits (611), Expect = 4e-63
Identities = 146/428 (34%), Positives = 231/428 (53%), Gaps = 15/428 (3%)
Query: 50 ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109
E P Y+EHP + ++E ++ I V+G +P+++F + P + +
Sbjct: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNL 218
Query: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169
+ + PT IQ Q PV L G D++ A TGSGKT ++LLP I+ L P
Sbjct: 219 KKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTPS 273
Query: 170 CLVLAPTRELAQQVQQVAAEYCRAC-RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
L+L PTRELA Q+++ A E R+K+ + GG P PQ+ L++ V++ IATPGRL
Sbjct: 274 ALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRL 333
Query: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288
+D ++ L +V+DEAD ML MGF+ Q+ I++ I D QT++ SAT P + Q
Sbjct: 334 LDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQ 393
Query: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEK---ENKTI 345
LA L + + I G L N+ QI+ D K +KL EI+++K + +
Sbjct: 394 LASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLF----EILNDKKLFKPPVL 448
Query: 346 VFVETKRRCDELTRKMRR-DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404
VFV+ K D L+ +++ G ++ IH +KSQ ER +L G ++++T V RG
Sbjct: 449 VFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRG 508
Query: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464
LD+ V+ V+N+D P+S ++Y+H+IGR R + GTA TF N+ + D+ ++
Sbjct: 509 LDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTG 568
Query: 465 QAINPKLL 472
+ P+LL
Sbjct: 569 SILPPQLL 576
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 214 bits (544), Expect = 2e-55
Identities = 133/339 (39%), Positives = 192/339 (56%), Gaps = 10/339 (2%)
Query: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
+T+PT IQ + P+AL G D++G+A+TGSGKT ++ LP + LE LVL
Sbjct: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
Query: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
PTRELA Q+ + + ++S I GG Q L + I IATPGRLID LE
Sbjct: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
Query: 234 CGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 292
K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
Query: 293 FLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352
LK+ + + + + + Q KD L+ ++ E+ N ++F T
Sbjct: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274
Query: 353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412
+R G+ A+ +HG SQ +R LN+FK IL+ATDVASRGLD+ V
Sbjct: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334
Query: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK 451
V+N+D P S+DYIHR+GRTAR+ ++G A TF T +++
Sbjct: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 373
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 203 bits (517), Expect = 3e-52
Identities = 138/433 (31%), Positives = 227/433 (52%), Gaps = 29/433 (6%)
Query: 30 SGKKFGNPGEKLVKKKWNL-----DELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITV 84
S ++ P K +KK+ + ++ PK + F PD A E+ ++
Sbjct: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ--- 177
Query: 85 RGHNCPKPVLNFYEANFPAN--VMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGS 142
P +NFP + + ++ + T IQA+ + SG D++ A+TG+
Sbjct: 178 ---EIPVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGT 234
Query: 143 GKTLSYLLPAIVHINHQ-PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCI 201
GKT S+ +P I ++ + +RG P LVLAPTRELA QV + ++ + +L C
Sbjct: 235 GKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACF 292
Query: 202 YGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQ 261
YGG P G Q + G++I + TPGR+ D ++ GK +L + ++VLDE D+MLDMGF Q
Sbjct: 293 YGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQ 352
Query: 262 IRKIVD-----QIRPDRQTLMWSATWPKEVRQLAEDFLKD-YIHIN-IGALELSANHNIL 314
+ +I+ + QTL++SAT P V +A+ ++K Y ++ IG +
Sbjct: 353 VEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVE 412
Query: 315 QIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK--MRRDGWPAMGIH 372
+ CH ++ +I + + S + +TI+F ETK+ EL++ +++D A +H
Sbjct: 413 HLAIKCHWTQR-AAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQD---AQSLH 468
Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
GD Q++R+ L F++G +L+AT+VA+RGLD+ +V VI P E YIHR GRT
Sbjct: 469 GDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRT 528
Query: 433 ARSTKTGTAYTFF 445
R+ +TG F+
Sbjct: 529 GRAGRTGVCICFY 541
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 197 bits (502), Expect = 2e-50
Identities = 125/371 (33%), Positives = 195/371 (52%), Gaps = 8/371 (2%)
Query: 94 LNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI 153
L+F + N ++ I F +PT IQ PV L G D+ A TG+GKT ++ LP +
Sbjct: 218 LSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVL 277
Query: 154 VHINHQPFLERGDGPIC--LVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQI 211
+ ++P P+ LVL PTREL QV V + + C + + GG Q
Sbjct: 278 ERLIYKP----RQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQE 333
Query: 212 RDLERGVEICIATPGRLIDFLE-CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIR 270
L +I IATPGRLID L C +L L+LDEADRMLD FE Q+++I+
Sbjct: 334 AALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCS 393
Query: 271 PDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLI 330
RQT+++SAT EV+ LA LK+ + I + + A + + + + E D + I
Sbjct: 394 HHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAI 453
Query: 331 RLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHG 390
+ + + ++F +TK++ + + G +HG+ SQ +R L FK
Sbjct: 454 -VAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDE 512
Query: 391 KAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNI 450
+ IL+ATDVA+RGLD+E VK VIN+ PN+ + Y+HR+GRTAR+ + G + + +
Sbjct: 513 QIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDER 572
Query: 451 KQVSDLISVLR 461
K + +++ +
Sbjct: 573 KMLKEIVKAAK 583
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 197 bits (501), Expect = 2e-50
Identities = 120/365 (32%), Positives = 199/365 (54%), Gaps = 14/365 (3%)
Query: 99 ANFPAN--VMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI 156
+NFP + + ++ + T IQ + + G D++ A+TG+GKT S+ +P I +
Sbjct: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199
Query: 157 N-HQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLE 215
+Q +++ P LVLAPTRELA QV + + R +L C YGG QI +
Sbjct: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSYQSQINHIR 257
Query: 216 RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI-----R 270
G++I + TPGR+ D L+ G+ +L + ++VLDE D+MLD+GF Q+ I+ +
Sbjct: 258 NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSE 317
Query: 271 PDRQTLMWSATWPKEVRQLAEDFLKD-YIHIN-IGALELSANHNILQIVDVCHDVEKDEK 328
+ QTL++SAT P+ V ++A+ ++K Y ++ +G + A + + CH ++
Sbjct: 318 DNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAV 377
Query: 329 LIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFK 388
+ +++ + S E + I+F ETK+ E+ A +HGD +Q +R+ L F+
Sbjct: 378 IGDVLQ-VYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLKGFR 435
Query: 389 HGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPN 448
G +L+AT+VA+RGLD+ +V VI P E YIHR GRT R+ +TG F+ P
Sbjct: 436 EGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPR 495
Query: 449 NIKQV 453
Q+
Sbjct: 496 ERGQL 500
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 196 bits (497), Expect = 7e-50
Identities = 118/343 (34%), Positives = 183/343 (53%), Gaps = 8/343 (2%)
Query: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
F +P+AIQ + + G D++ +Q+G+GKT ++ + + ++ Q + L+L
Sbjct: 58 FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQA-----LIL 112
Query: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
APTRELA Q+Q+ ++ GG G IR L+ G + TPGR+ D +
Sbjct: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172
Query: 234 CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 293
R LVLDEAD ML+ GF+ QI + + P Q ++ SAT P E+ ++ F
Sbjct: 173 RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKF 232
Query: 294 LKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRR 353
+ D I I + EL+ V V + K + L L + + + ++F TKR+
Sbjct: 233 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 289
Query: 354 CDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFV 413
D LT KMR + +HGD Q+ER+ ++ EF+ G + +LI+TDV +RGLDV V +
Sbjct: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349
Query: 414 INYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456
INYD PN+ E YIHRIGR+ R + G A F ++I+ + D+
Sbjct: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 195 bits (495), Expect = 1e-49
Identities = 126/371 (33%), Positives = 199/371 (53%), Gaps = 25/371 (6%)
Query: 95 NFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIV 154
NF + N +++ I F +P+AIQ + + G D++ AQ+G+GKT ++ + +
Sbjct: 34 NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 93
Query: 155 HINHQPFLERGDGPICLVLAPTRELAQQVQQVA---AEY----CRACRLKSTCIYGGAPK 207
+ + F E LVLAPTRELAQQ+Q+V +Y C AC GG
Sbjct: 94 QLEIE-FKETQ----ALVLAPTRELAQQIQKVILALGDYMGATCHAC-------IGGTNV 141
Query: 208 GPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIV 266
+++ L+ I + TPGR+ D L + + VLDEAD ML GF+ QI +I
Sbjct: 142 RNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIF 201
Query: 267 DQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKD 326
++ Q ++ SAT P +V ++ + F++D I I + EL+ I +VE++
Sbjct: 202 QKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEG----IKQFYINVERE 257
Query: 327 E-KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLN 385
E KL L + + + ++F+ T+R+ D LT KM + +HGD Q+ERD ++
Sbjct: 258 EWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMR 317
Query: 386 EFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFF 445
EF+ G + +LI TD+ +RG+DV+ V VINYD P + E+YIHRIGR R + G A F
Sbjct: 318 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFV 377
Query: 446 TPNNIKQVSDL 456
T + + + D+
Sbjct: 378 TEEDKRILRDI 388
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 193 bits (491), Expect = 3e-49
Identities = 123/371 (33%), Positives = 196/371 (52%), Gaps = 25/371 (6%)
Query: 95 NFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIV 154
+F + N +++ I F +P+AIQ + + G D++ AQ+G+GKT ++ + +
Sbjct: 33 SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92
Query: 155 HINHQPFLERGDGPICLVLAPTRELAQQVQQVA---AEY----CRACRLKSTCIYGGAPK 207
I + LVLAPTRELAQQ+Q+V +Y C AC GG
Sbjct: 93 QIELDLKATQA-----LVLAPTRELAQQIQKVVMALGDYMGASCHAC-------IGGTNV 140
Query: 208 GPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIV 266
+++ L+ I + TPGR+ D L + + VLDEAD ML GF+ QI I
Sbjct: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200
Query: 267 DQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKD 326
++ + Q ++ SAT P +V ++ + F++D I I + EL+ I +VE++
Sbjct: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEG----IRQFYINVERE 256
Query: 327 E-KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLN 385
E KL L + + + ++F+ T+R+ D LT KM + +HGD Q+ERD ++
Sbjct: 257 EWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316
Query: 386 EFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFF 445
EF+ G + +LI TD+ +RG+DV+ V VINYD P + E+YIHRIGR R + G A
Sbjct: 317 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376
Query: 446 TPNNIKQVSDL 456
T + + + D+
Sbjct: 377 TEEDKRTLRDI 387
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 191 bits (484), Expect = 2e-48
Identities = 125/363 (34%), Positives = 189/363 (52%), Gaps = 11/363 (3%)
Query: 96 FYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVH 155
F E + +++ + +PT +Q P L G D +G A+TGSGKT +++LP +
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
Query: 156 INHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLE 215
++ P+ G CLVL PTRELA Q+ + + LK I GG Q +L
Sbjct: 64 LSEDPY-----GIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELS 118
Query: 216 RGVEICIATPGRLIDFLECGKT-NLRRTTYLVLDEADRMLDMG---FEPQIRKIVDQIRP 271
R + IATPGRL D L T ++++ +LV+DEADR+L+ G F + I+ +
Sbjct: 119 RKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPA 178
Query: 272 DRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIR 331
RQTL++SAT +R+L + + +S + Q + + KD L+
Sbjct: 179 RRQTLLFSATLTDTLREL-QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVH 237
Query: 332 LMEEIMSEKEN-KTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHG 390
L++ E E+ I+F T + C L +R+ +P + +H Q+ER L +FK
Sbjct: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297
Query: 391 KAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNI 450
ILIATDVASRGLD+ V+ VIN++ P + YIHR+GRTAR+ + G A T T +I
Sbjct: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357
Query: 451 KQV 453
V
Sbjct: 358 HLV 360
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 185 bits (470), Expect = 9e-47
Identities = 116/348 (33%), Positives = 182/348 (52%), Gaps = 5/348 (1%)
Query: 109 IARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGP 168
I ++ + PT IQ + PV L G D+V +A+TGSGKT +LLP + G
Sbjct: 111 IMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTH---SAQTGA 167
Query: 169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
L+L+PTRELA Q + E + LK+ I GG Q L +I IATPGRL
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRL 227
Query: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288
+ L+ Y+V DEADR+ +MGF Q+++I+ ++ QT+++SAT PK + +
Sbjct: 228 VHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVE 287
Query: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFV 348
A L + + I + ++ N + + + K L+ L+ ++ +++T+VFV
Sbjct: 288 FARAGLTEPVLIRLD-VDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV-RPQDQTVVFV 345
Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
TK + LT + I+ R L +F GK LI TD+A+RGLD+
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405
Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456
+ VINY +P + ++HR+GR AR+ ++GTAY+ P+ I + DL
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 185 bits (470), Expect = 9e-47
Identities = 116/348 (33%), Positives = 182/348 (52%), Gaps = 5/348 (1%)
Query: 109 IARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGP 168
I ++ + PT IQ + PV L G D+V +A+TGSGKT +LLP + G
Sbjct: 111 IMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTH---SAQTGA 167
Query: 169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
L+L+PTRELA Q + E + LK+ I GG Q L +I IATPGRL
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRL 227
Query: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288
+ L+ Y+V DEADR+ +MGF Q+++I+ ++ QT+++SAT PK + +
Sbjct: 228 VHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVE 287
Query: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFV 348
A L + + I + ++ N + + + K L+ L+ ++ +++T+VFV
Sbjct: 288 FARAGLTEPVLIRLD-VDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV-RPQDQTVVFV 345
Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
TK + LT + I+ R L +F GK LI TD+A+RGLD+
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405
Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456
+ VINY +P + ++HR+GR AR+ ++GTAY+ P+ I + DL
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 180 bits (456), Expect = 4e-45
Identities = 122/339 (35%), Positives = 174/339 (51%), Gaps = 59/339 (17%)
Query: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
+T+PT IQ + P+AL G D++G+A+TGSGKT ++ LP + LE LVL
Sbjct: 44 WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98
Query: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
PTRELA Q+ + + ++S I GG Q L + I IATPGRLID LE
Sbjct: 99 TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158
Query: 234 CGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 292
K NLR YLV+DEADR+L+M FE ++ KI+ I DR+T ++SAT K+V++L
Sbjct: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218
Query: 293 FLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352
LK+ + + + + EK + +F+ +K
Sbjct: 219 ALKNPVKCAVSSKYQTV-----------------------------EKLQQYYIFIPSKF 249
Query: 353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412
+ L LN+FK IL+ATDVASRGLD+ V
Sbjct: 250 KSKRLGS------------------------LNKFKAKARSILLATDVASRGLDIPHVDV 285
Query: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK 451
V+N+D P S+DYIHR+GRTAR+ ++G A TF T +++
Sbjct: 286 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 324
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 176 bits (446), Expect = 6e-44
Identities = 109/332 (32%), Positives = 179/332 (53%), Gaps = 3/332 (0%)
Query: 104 NVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLE 163
N + I FT T IQ + L G D++ A+TGSGKTL++L+PA+ I F+
Sbjct: 189 NTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMP 248
Query: 164 RGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIA 223
R +G L+L+PTRELA Q V E I GG+ + + + L G+ I +A
Sbjct: 249 R-NGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVA 307
Query: 224 TPGRLIDFLECGKTNLRRTTY-LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATW 282
TPGRL+D ++ + + LV+DEADR+LD+GFE ++++I+ + RQT+++SAT
Sbjct: 308 TPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQ 367
Query: 283 PKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKEN 342
++V LA LK + +G + AN + + +++ + L + ++
Sbjct: 368 TRKVEDLARISLKKE-PLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKK 426
Query: 343 KTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVAS 402
K +VF + + P + IHG + Q +R +F + + L+ TDVA+
Sbjct: 427 KLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAA 486
Query: 403 RGLDVEDVKFVINYDYPNSSEDYIHRIGRTAR 434
RGLD+ +V +++ YD P+ ++YIHR+GRTAR
Sbjct: 487 RGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR 518
>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
[Homo sapiens]
Length = 851
Score = 175 bits (444), Expect = 1e-43
Identities = 125/395 (31%), Positives = 198/395 (50%), Gaps = 58/395 (14%)
Query: 118 TAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHIN-HQPFLERGDGPICLVLAPT 176
T++Q Q PV L G D + +QTGSGKTL+Y +P + + + ++R DGP LVL PT
Sbjct: 255 TSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPT 314
Query: 177 RELAQQVQQVAAEYCRACR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECG 235
RELA Q + + + + GG + + L +G+ I I+TPGRL+D ++
Sbjct: 315 RELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKST 374
Query: 236 KT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPD---RQTLMWSATWPKEVRQLAE 291
K + R +LV DEADR+LD+GFE I I++ + + RQ ++ SAT + V +LA+
Sbjct: 375 KNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLAD 434
Query: 292 DFLKDYIHINIGALELSANHNILQ-----IVDVCHDVEKDE------------------- 327
L D + I++ L +H+ L + +VC D+
Sbjct: 435 ISLHDPVSISV----LDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPS 490
Query: 328 --KLIRL----MEEIMSEKENKTIVFVETKRRCD-----ELTRKMRRDGWPAMG------ 370
+L+ L +++ E++ K +VF + + L + G PA G
Sbjct: 491 KLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSAS 550
Query: 371 -------IHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSE 423
+HG Q+ER V EF H + +L+ TDVA+RGLD+ V +++ Y+ P+S
Sbjct: 551 MRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPA 610
Query: 424 DYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLIS 458
+YIHRIGRTAR G++ P+ + V+ L S
Sbjct: 611 EYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLAS 645
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,996,273
Number of Sequences: 37866
Number of extensions: 1141498
Number of successful extensions: 3421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3135
Number of HSP's gapped (non-prelim): 166
length of query: 614
length of database: 18,247,518
effective HSP length: 108
effective length of query: 506
effective length of database: 14,157,990
effective search space: 7163942940
effective search space used: 7163942940
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.