Guide to the Human Genome
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Search of human proteins with 4758138

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo
sapiens]
         (614 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]   1256   0.0  
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         807   0.0  
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          802   0.0  
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            362   e-100
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            362   e-100
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   360   3e-99
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   343   3e-94
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...   330   3e-90
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   328   7e-90
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   328   7e-90
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   327   2e-89
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   291   9e-79
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...   291   9e-79
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...   291   9e-79
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   285   7e-77
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  271   1e-72
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   239   4e-63
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   214   2e-55
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   203   3e-52
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   197   2e-50
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      197   2e-50
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   196   7e-50
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   195   1e-49
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   193   3e-49
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   191   2e-48
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   185   9e-47
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   185   9e-47
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   180   4e-45
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi...   176   6e-44
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ...   175   1e-43

>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score = 1256 bits (3251), Expect = 0.0
 Identities = 614/614 (100%), Positives = 614/614 (100%)

Query: 1   MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 60
           MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ
Sbjct: 1   MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQ 60

Query: 61  EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 120
           EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI
Sbjct: 61  EHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAI 120

Query: 121 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 180
           QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA
Sbjct: 121 QAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELA 180

Query: 181 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 240
           QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR
Sbjct: 181 QQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLR 240

Query: 241 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 300
           RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI
Sbjct: 241 RTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHI 300

Query: 301 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 360
           NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK
Sbjct: 301 NIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK 360

Query: 361 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 420
           MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN
Sbjct: 361 MRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPN 420

Query: 421 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 480
           SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS
Sbjct: 421 SSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGS 480

Query: 481 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 540
           GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY
Sbjct: 481 GRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANY 540

Query: 541 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 600
           TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA
Sbjct: 541 TNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAA 600

Query: 601 APMIGYPMPTGYSQ 614
           APMIGYPMPTGYSQ
Sbjct: 601 APMIGYPMPTGYSQ 614


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  807 bits (2085), Expect = 0.0
 Identities = 435/645 (67%), Positives = 482/645 (74%), Gaps = 45/645 (6%)

Query: 3   GYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEH 62
           G   DRDR RDRG     FG    G L  KKFGNPGE+L KKKW+L ELPKFEKNFY EH
Sbjct: 83  GGFGDRDRDRDRG----GFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEH 138

Query: 63  PDLARRTAQEVETYRRSKEITVRGHN-CPKPVLNFYEANFPANVMDVIARQNFTEPTAIQ 121
           P++AR T  EV+  RR KEITVRG + CPKPV  F+ ANFP  VMDV+  Q+FTEPT IQ
Sbjct: 139 PEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQ 198

Query: 122 AQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQ 181
            QG+P+ALSG DMVG+AQTGSGKTL+YLLPAIVHINHQP+LERGDGPICLVLAPTRELAQ
Sbjct: 199 CQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQ 258

Query: 182 QVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRR 241
           QVQQVA +Y +  RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE GKTNLRR
Sbjct: 259 QVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRR 318

Query: 242 TTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHIN 301
            TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFL+DY  IN
Sbjct: 319 CTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQIN 378

Query: 302 IGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM 361
           +G LELSANHNILQIVDVC + EKD KLI+LMEEIM+EKENKTI+FVETKRRCD+LTR+M
Sbjct: 379 VGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRM 438

Query: 362 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 421
           RRDGWPAM IHGDKSQ ERDWVLNEF+ GKAPILIATDVASRGLDVEDVKFVINYDYPNS
Sbjct: 439 RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS 498

Query: 422 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSG 481
           SEDY+HRIGRTARST  GTAYTFFTP N+KQ  +LI VL EANQAINPKL+QLV+ RG G
Sbjct: 499 SEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGG 558

Query: 482 RSRGRGG---------------MKDDRRDRYSAGKRGGFN----TFRDRENYDR------ 516
              G+GG               M  D  DR   G + G      ++RDR   DR      
Sbjct: 559 GGGGKGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANG 618

Query: 517 -GYSSLLKRDFGAKT-----QNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNG 570
            GY S     FGA+        G Y AA Y   S+ +    AG   ++   + T T ++ 
Sbjct: 619 SGYGS-PNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG---TYGASSTTSTGRSS 674

Query: 571 YDSTQQY---GSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGY 612
             S+QQ+   G +       M+QQ +A P   A  MIGY   T Y
Sbjct: 675 QSSSQQFSGIGRSGQQPQPLMSQQ-FAQP-PGATNMIGYMGQTAY 717


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  802 bits (2072), Expect = 0.0
 Identities = 436/643 (67%), Positives = 482/643 (74%), Gaps = 43/643 (6%)

Query: 3   GYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEH 62
           G   DRDR RDRG     FG    G L  KKFGNPGE+L KKKW+L ELPKFEKNFY EH
Sbjct: 83  GGFGDRDRDRDRG----GFGARGGGGLPPKKFGNPGERLRKKKWDLSELPKFEKNFYVEH 138

Query: 63  PDLARRTAQEVETYRRSKEITVRGHN-CPKPVLNFYEANFPANVMDVIARQNFTEPTAIQ 121
           P++AR T  EV+  RR KEITVRG + CPKPV  F+ ANFP  VMDV+  Q+FTEPT IQ
Sbjct: 139 PEVARLTPYEVDELRRKKEITVRGGDVCPKPVFAFHHANFPQYVMDVLMDQHFTEPTPIQ 198

Query: 122 AQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQ 181
            QG+P+ALSG DMVG+AQTGSGKTL+YLLPAIVHINHQP+LERGDGPICLVLAPTRELAQ
Sbjct: 199 CQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPTRELAQ 258

Query: 182 QVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRR 241
           QVQQVA +Y +  RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE GKTNLRR
Sbjct: 259 QVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLESGKTNLRR 318

Query: 242 TTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHIN 301
            TYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFL+DY  IN
Sbjct: 319 CTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQIN 378

Query: 302 IGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKM 361
           +G LELSANHNILQIVDVC + EKD KLI+LMEEIM+EKENKTI+FVETKRRCD+LTR+M
Sbjct: 379 VGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRM 438

Query: 362 RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNS 421
           RRDGWPAM IHGDKSQ ERDWVLNEF+ GKAPILIATDVASRGLDVEDVKFVINYDYPNS
Sbjct: 439 RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRGLDVEDVKFVINYDYPNS 498

Query: 422 SEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDR--- 478
           SEDY+HRIGRTARST  GTAYTFFTP N+KQ  +LI VL EANQAINPKL+QLV+ R   
Sbjct: 499 SEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIKVLEEANQAINPKLMQLVDHRGGG 558

Query: 479 --GSGRSRGR--------GGMKDDRRDRYSAGKRGGFN----TFRDRENYDR-------G 517
             G GRSR R          M  D  DR   G + G      ++RDR   DR       G
Sbjct: 559 GGGGGRSRYRTTSSANNPNLMYQDECDRRLRGVKDGGRRDSASYRDRSETDRAGYANGSG 618

Query: 518 YSSLLKRDFGAKT-----QNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYD 572
           Y S     FGA+        G Y AA Y   S+ +    AG   ++   + T T ++   
Sbjct: 619 YGS-PNSAFGAQAGQYTYGQGTYGAAAYGTSSYTAQEYGAG---TYGASSTTSTGRSSQS 674

Query: 573 STQQY---GSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGY 612
           S+QQ+   G +       M+QQ +A P   A  MIGY   T Y
Sbjct: 675 SSQQFSGIGRSGQQPQPLMSQQ-FAQP-PGATNMIGYMGQTAY 715


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  362 bits (929), Expect = e-100
 Identities = 213/552 (38%), Positives = 311/552 (56%), Gaps = 37/552 (6%)

Query: 50  ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109
           + P FEKNFY EH ++   T Q++   R    + V G   P+P  +F    F   +M  I
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQI 268

Query: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169
            +  +T+PT IQ QG PVALSG DM+G+A+TGSGKT +++ P ++HI  Q  LE GDGPI
Sbjct: 269 RKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPI 328

Query: 170 CLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLI 229
            +++ PTREL QQ+      + +A  L+S  +YGG     Q + L+ G EI + TPGRLI
Sbjct: 329 AVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLI 388

Query: 230 DFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289
           D ++   TNL+R +YLV DEADRM DMGFE Q+R I   +RPDRQTL++SAT+ K++ +L
Sbjct: 389 DHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKL 448

Query: 290 AEDFLKDYIHINIGALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFV 348
           A D L D I +  G +   AN ++ QIV++ H    K   L R + E  S      ++FV
Sbjct: 449 ARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFV 505

Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
             K   +EL   ++++G     +HGD  Q ER+ V+++FK    P+L+ATDVA+RGLD+ 
Sbjct: 506 TKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIP 565

Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAIN 468
            +K VINYD     + + HRIGRT R+ + G AYT  TP +     DL+  L  ANQ ++
Sbjct: 566 SIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVS 625

Query: 469 PKLLQL-VEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLL 522
            +LL L +++    +SR +GG    +  + + G  GG   +R+R     EN DRG ++++
Sbjct: 626 KELLDLAMQNAWFRKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVM 679

Query: 523 KRDFGAKTQNGV-------------------YSAANYTNGSFGSNFVSAGIQTSFRTGN- 562
                 K   G                    + AA+ +N   GS+   A   TS  + N 
Sbjct: 680 SNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNS 739

Query: 563 -PTGTYQNGYDS 573
            PT + Q G++S
Sbjct: 740 VPTNSAQQGHNS 751


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  362 bits (929), Expect = e-100
 Identities = 213/552 (38%), Positives = 311/552 (56%), Gaps = 37/552 (6%)

Query: 50  ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109
           + P FEKNFY EH ++   T Q++   R    + V G   P+P  +F    F   +M  I
Sbjct: 209 DYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQI 268

Query: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169
            +  +T+PT IQ QG PVALSG DM+G+A+TGSGKT +++ P ++HI  Q  LE GDGPI
Sbjct: 269 RKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPI 328

Query: 170 CLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLI 229
            +++ PTREL QQ+      + +A  L+S  +YGG     Q + L+ G EI + TPGRLI
Sbjct: 329 AVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLI 388

Query: 230 DFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQL 289
           D ++   TNL+R +YLV DEADRM DMGFE Q+R I   +RPDRQTL++SAT+ K++ +L
Sbjct: 389 DHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKL 448

Query: 290 AEDFLKDYIHINIGALELSANHNILQIVDVCHD-VEKDEKLIRLMEEIMSEKENKTIVFV 348
           A D L D I +  G +   AN ++ QIV++ H    K   L R + E  S      ++FV
Sbjct: 449 ARDILIDPIRVVQGDIG-EANEDVTQIVEILHSGPSKWNWLTRRLVEFTS--SGSVLLFV 505

Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
             K   +EL   ++++G     +HGD  Q ER+ V+++FK    P+L+ATDVA+RGLD+ 
Sbjct: 506 TKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIP 565

Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAIN 468
            +K VINYD     + + HRIGRT R+ + G AYT  TP +     DL+  L  ANQ ++
Sbjct: 566 SIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVS 625

Query: 469 PKLLQL-VEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDR-----ENYDRGYSSLL 522
            +LL L +++    +SR +GG    +  + + G  GG   +R+R     EN DRG ++++
Sbjct: 626 KELLDLAMQNAWFRKSRFKGG----KGKKLNIG--GGGLGYRERPGLGSENMDRGNNNVM 679

Query: 523 KRDFGAKTQNGV-------------------YSAANYTNGSFGSNFVSAGIQTSFRTGN- 562
                 K   G                    + AA+ +N   GS+   A   TS  + N 
Sbjct: 680 SNYEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGSSAAGASGWTSAGSLNS 739

Query: 563 -PTGTYQNGYDS 573
            PT + Q G++S
Sbjct: 740 VPTNSAQQGHNS 751


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  360 bits (923), Expect = 3e-99
 Identities = 179/433 (41%), Positives = 270/433 (62%), Gaps = 9/433 (2%)

Query: 50  ELPKFEKNFYQEHPDLARRTAQEVETYRRSKE-ITVRGHNCPKPVLNFYEANFPANVMDV 108
           E   F KNFY E P+LA+ + +EV  +R   E ITV+G  CPKP+ ++ +      +++ 
Sbjct: 327 EYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNS 386

Query: 109 IARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGP 168
           + +  + +PT IQ Q  P  +SG D++G+A+TGSGKT+++LLP   HI  Q  LE G+GP
Sbjct: 387 LKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGP 446

Query: 169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
           I +++ PTRELA Q+ +   ++ +   L+  C+YGG     QI +L+RG EI + TPGR+
Sbjct: 447 IAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRM 506

Query: 229 IDFLECGK---TNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKE 285
           ID L       TNLRR TY+VLDEADRM DMGFEPQ+ +IVD +RPDRQT+M+SAT+P+ 
Sbjct: 507 IDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRA 566

Query: 286 VRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKEN-KT 344
           +  LA   L   I + +G   +  +    Q++     +E+++K ++L+E +   +E+   
Sbjct: 567 MEALARRILSKPIEVQVGGRSVVCSDVEQQVI----VIEEEKKFLKLLELLGHYQESGSV 622

Query: 345 IVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404
           I+FV+ +   D L + + R  +P M +HG   Q +RD ++N+FK+G   +L+AT VA+RG
Sbjct: 623 IIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARG 682

Query: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464
           LDV+ +  V+NY  PN  EDY+HR GRT R+   G AYTF T +  +   D+I  L  + 
Sbjct: 683 LDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSG 742

Query: 465 QAINPKLLQLVED 477
            A+ P L +L  D
Sbjct: 743 TAVPPDLEKLWSD 755


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  343 bits (880), Expect = 3e-94
 Identities = 195/449 (43%), Positives = 277/449 (61%), Gaps = 16/449 (3%)

Query: 38  GEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSK-EITV------RGHNCP 90
           G K  K KW   +LP  +KNFY+E    +  +  E +++R+    IT            P
Sbjct: 180 GLKWQKTKWA--DLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIP 237

Query: 91  KPVLNFYEAN--FPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSY 148
            P   F +A   +P  VM+ I +  F +PT IQ+Q WP+ L G+D++GVAQTG+GKTL Y
Sbjct: 238 NPTCTFDDAFQCYP-EVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCY 296

Query: 149 LLPAIVHINHQPFLE-RGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPK 207
           L+P  +H+  QP L+ + + P  LVL PTRELA QV+    +Y     L+S C+YGG  +
Sbjct: 297 LMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYK-GLRSVCVYGGGNR 355

Query: 208 GPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVD 267
             QI +L++GV+I IATPGRL D       NL+  TYLVLDEAD+MLDMGFEPQI KI+ 
Sbjct: 356 DEQIEELKKGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILL 415

Query: 268 QIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDE 327
            +RPDRQT+M SATWP  V +LA+ +LK+ + + +G L+L A  ++ Q + V  + EK  
Sbjct: 416 DVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWS 475

Query: 328 KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEF 387
            +   ++ + S   +K IVFV  K   D L+  +         +HGD+ Q++R+  L  F
Sbjct: 476 HMQTFLQSMSS--TDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENF 533

Query: 388 KHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTP 447
           K GK  ILIATD+ASRGLDV DV  V N+D+P + E+Y+HRIGRT R+ +TG + T  T 
Sbjct: 534 KTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTR 593

Query: 448 NNIKQVSDLISVLREANQAINPKLLQLVE 476
           N+ +  S+LI++L  ANQ+I  +L+ + E
Sbjct: 594 NDWRVASELINILERANQSIPEELVSMAE 622


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score =  330 bits (845), Expect = 3e-90
 Identities = 191/444 (43%), Positives = 265/444 (59%), Gaps = 16/444 (3%)

Query: 43  KKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSK-EITV------RGHNCPKPVLN 95
           K+KW   +LP  +KNFY E    +  +  +V  +R+    IT            PKP   
Sbjct: 165 KRKWA--DLPPVKKNFYIESKATSCMSEMQVINWRKENFNITCDDLKSGEKRLIPKPTCR 222

Query: 96  FYEA--NFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI 153
           F +A   +P +++  I R    +PT IQ+Q WP+ L G+D++ VAQTG+GKTLSYL+P  
Sbjct: 223 FKDAFQQYP-DLLKSIIRVGIVKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGF 281

Query: 154 VHINHQPFL-ERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIR 212
           +H++ QP   E+ +GP  LVL PTRELA  V+   ++Y     LKS CIYGG  +  QI 
Sbjct: 282 IHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYSYK-GLKSICIYGGRNRNGQIE 340

Query: 213 DLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPD 272
           D+ +GV+I IATPGRL D       NLR  TYLV+DEAD+MLDM FEPQIRKI+  +RPD
Sbjct: 341 DISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPD 400

Query: 273 RQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRL 332
           RQT+M SATWP  VRQLA  +LKD + + +G L L A + + Q + V  + EK   L + 
Sbjct: 401 RQTVMTSATWPDTVRQLALSYLKDPMIVYVGNLNLVAVNTVKQNIIVTTEKEK-RALTQE 459

Query: 333 MEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKA 392
             E MS  + K I+FV  K   D+L+      G  A  +HG+  Q +++  + +FK G  
Sbjct: 460 FVENMSPND-KVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNI 518

Query: 393 PILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQ 452
            ILI TD+ SRGLD+ DV  V NYD+P + + Y+HR+G   R+ KTGT+ T  T  + K 
Sbjct: 519 KILITTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKM 578

Query: 453 VSDLISVLREANQAINPKLLQLVE 476
             +LI +L  ANQ++   L+ + E
Sbjct: 579 AGELIKILDRANQSVPEDLVVMAE 602


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  328 bits (842), Expect = 7e-90
 Identities = 223/589 (37%), Positives = 313/589 (53%), Gaps = 52/589 (8%)

Query: 3   GYSSDR---DRGR--DRGFGAPRFGGSRAGPLSGKKFGNPG-----EKLVKKKWNLDELP 52
           GY S+R    RGR  DRG       G+R  P  G+ F   G     +K V+  W+   LP
Sbjct: 82  GYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGR-FERSGHSRWCDKSVEDDWS-KPLP 139

Query: 53  KFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQ 112
             E+   ++       T    E Y     +   G NCP  + NF + +    +M  I   
Sbjct: 140 PSER--LEQELFSGGNTGINFEKYD-DIPVEATGSNCPPHIENFSDIDMGEIIMGNIELT 196

Query: 113 NFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI-------------NHQ 159
            +T PT +Q    P+     D++  AQTGSGKT ++LLP +  I              + 
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256

Query: 160 PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVE 219
            +  R   PI LVLAPTRELA Q+ + A ++    R++   +YGGA  G QIRDLERG  
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCH 316

Query: 220 ICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----RPDRQT 275
           + +ATPGRL+D +E GK  L    YLVLDEADRMLDMGFEPQIR+IV+Q     +  R T
Sbjct: 317 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHT 376

Query: 276 LMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEE 335
           +M+SAT+PKE++ LA DFL +YI + +G +  S + NI Q V    D++K   L+ ++  
Sbjct: 377 MMFSATFPKEIQMLARDFLDEYIFLAVGRVG-STSENITQKVVWVEDLDKRSFLLDILGA 435

Query: 336 IMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPIL 395
             S+  + T+VFVETK+  D L   +  +G+    IHGD+SQ++R+  L++F+ GK+PIL
Sbjct: 436 TGSD--SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPIL 493

Query: 396 IATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSD 455
           +AT VA+RGLD+ +V+ VIN+D P+  E+Y+HRIGRT R    G A +FF   N+    D
Sbjct: 494 VATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKD 553

Query: 456 LISVLREANQAINPKLLQLV-EDRGSGRSRGRG---------GMKDDRRDRYSAGKRGGF 505
           L+ +L EA Q +   L  +  E    G SRGR          G +D R+   S     GF
Sbjct: 554 LLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQS--SGSSSSGF 611

Query: 506 NTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGI 554
              R   +   G      R FG     G Y++  Y     G N+ S G+
Sbjct: 612 GASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGY-----GGNYNSQGV 655


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  328 bits (842), Expect = 7e-90
 Identities = 223/589 (37%), Positives = 313/589 (53%), Gaps = 52/589 (8%)

Query: 3   GYSSDR---DRGR--DRGFGAPRFGGSRAGPLSGKKFGNPG-----EKLVKKKWNLDELP 52
           GY S+R    RGR  DRG       G+R  P  G+ F   G     +K V+  W+   LP
Sbjct: 82  GYFSERGSGSRGRFDDRGRSDYDGIGNRERPGFGR-FERSGHSRWCDKSVEDDWS-KPLP 139

Query: 53  KFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQ 112
             E+   ++       T    E Y     +   G NCP  + NF + +    +M  I   
Sbjct: 140 PSER--LEQELFSGGNTGINFEKYD-DIPVEATGSNCPPHIENFSDIDMGEIIMGNIELT 196

Query: 113 NFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI-------------NHQ 159
            +T PT +Q    P+     D++  AQTGSGKT ++LLP +  I              + 
Sbjct: 197 RYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENG 256

Query: 160 PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVE 219
            +  R   PI LVLAPTRELA Q+ + A ++    R++   +YGGA  G QIRDLERG  
Sbjct: 257 RYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCH 316

Query: 220 ICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----RPDRQT 275
           + +ATPGRL+D +E GK  L    YLVLDEADRMLDMGFEPQIR+IV+Q     +  R T
Sbjct: 317 LLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHT 376

Query: 276 LMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEE 335
           +M+SAT+PKE++ LA DFL +YI + +G +  S + NI Q V    D++K   L+ ++  
Sbjct: 377 MMFSATFPKEIQMLARDFLDEYIFLAVGRVG-STSENITQKVVWVEDLDKRSFLLDILGA 435

Query: 336 IMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPIL 395
             S+  + T+VFVETK+  D L   +  +G+    IHGD+SQ++R+  L++F+ GK+PIL
Sbjct: 436 TGSD--SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPIL 493

Query: 396 IATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSD 455
           +AT VA+RGLD+ +V+ VIN+D P+  E+Y+HRIGRT R    G A +FF   N+    D
Sbjct: 494 VATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKD 553

Query: 456 LISVLREANQAINPKLLQLV-EDRGSGRSRGRG---------GMKDDRRDRYSAGKRGGF 505
           L+ +L EA Q +   L  +  E    G SRGR          G +D R+   S     GF
Sbjct: 554 LLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKSNRFSGGFGARDYRQS--SGSSSSGF 611

Query: 506 NTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGI 554
              R   +   G      R FG     G Y++  Y     G N+ S G+
Sbjct: 612 GASRGSSSRSGGGGYGNSRGFGGGGYGGFYNSDGY-----GGNYNSQGV 655


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  327 bits (839), Expect = 2e-89
 Identities = 198/500 (39%), Positives = 280/500 (56%), Gaps = 37/500 (7%)

Query: 82  ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
           +   G+NCP  + +F +      +M  I    +T PT +Q    P+     D++  AQTG
Sbjct: 168 VEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTG 227

Query: 142 SGKTLSYLLPAIVHI-------------NHQPFLERGDGPICLVLAPTRELAQQVQQVAA 188
           SGKT ++LLP +  I              +  +  R   PI LVLAPTRELA Q+ + A 
Sbjct: 228 SGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEAR 287

Query: 189 EYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLD 248
           ++    R++   +YGGA  G QIRDLERG  + +ATPGRL+D +E GK  L    YLVLD
Sbjct: 288 KFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLD 347

Query: 249 EADRMLDMGFEPQIRKIVDQI----RPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGA 304
           EADRMLDMGFEPQIR+IV+Q     +  R T+M+SAT+PKE++ LA DFL +YI + +G 
Sbjct: 348 EADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGR 407

Query: 305 LELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRD 364
           +  S + NI Q V    + +K   L+ L+    + K++ T+VFVETK+  D L   +  +
Sbjct: 408 VG-STSENITQKVVWVEESDKRSFLLDLLNA--TGKDSLTLVFVETKKGADSLEDFLYHE 464

Query: 365 GWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSED 424
           G+    IHGD+SQ++R+  L++F+ GK+PIL+AT VA+RGLD+ +VK VIN+D P+  E+
Sbjct: 465 GYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEE 524

Query: 425 YIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLV-EDRGSGRS 483
           Y+HRIGRT R    G A +FF   NI    DL+ +L EA Q +   L  +  E    G S
Sbjct: 525 YVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSS 584

Query: 484 RGRG---------GMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGV 534
           RGR          G +D R+   S      F++ R   +   G      R FG     G 
Sbjct: 585 RGRSKSSRFSGGFGARDYRQS--SGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGF 642

Query: 535 YSAANYTNGSFGSNFVSAGI 554
           Y++  Y     G N+ S G+
Sbjct: 643 YNSDGY-----GGNYNSQGV 657


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  291 bits (746), Expect = 9e-79
 Identities = 171/455 (37%), Positives = 267/455 (58%), Gaps = 27/455 (5%)

Query: 82  ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
           + V GH+ P  +L F EAN    + + IA+  +T+ T +Q    P+ L+G D++  AQTG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335

Query: 142 SGKTLSYLLPAIVHINHQPF----LERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLK 197
           SGKT ++LLP + H+ H        +    P C+++APTREL  Q+   A ++     ++
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVR 395

Query: 198 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257
           +  IYGG   G  IR + +G  I  ATPGRL+D +   K  L++  YLVLDEADRMLDMG
Sbjct: 396 AVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMG 455

Query: 258 FEPQIRKIVD----QIRPDRQTLMWSATWPKEVRQLAEDFLK-DYIHINIGALELSANHN 312
           F P+++K++       +  RQTLM+SAT+P+E+++LA +FLK +Y+ + +G +   A  +
Sbjct: 456 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRD 514

Query: 313 ILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIH 372
           + Q V       K EKL+ ++  I  E+   T+VFVETK++ D +   + ++      IH
Sbjct: 515 VQQTVLQVGQFSKREKLVEILRNIGDER---TMVFVETKKKADFIATFLCQEKISTTSIH 571

Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
           GD+ Q+ER+  L +F+ GK P+L+AT VA+RGLD+E+V+ VIN+D P++ ++Y+HRIGRT
Sbjct: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631

Query: 433 ARSTKTGTAYTFF---TPNNIKQVSDLISVLREANQAINPKLLQLVEDR----GSGRSRG 485
            R   TG A +FF   + N++ Q   L+ VL +A Q +   L ++         SG +RG
Sbjct: 632 GRCGNTGRAISFFDLESDNHLAQ--PLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRG 689

Query: 486 RGGMKDDRRDRYSAGKRGGFNTFR-----DRENYD 515
                 D R   S     GF++ +     D E++D
Sbjct: 690 NVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD 724


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score =  291 bits (746), Expect = 9e-79
 Identities = 171/455 (37%), Positives = 267/455 (58%), Gaps = 27/455 (5%)

Query: 82  ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
           + V GH+ P  +L F EAN    + + IA+  +T+ T +Q    P+ L+G D++  AQTG
Sbjct: 276 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 335

Query: 142 SGKTLSYLLPAIVHINHQPF----LERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLK 197
           SGKT ++LLP + H+ H        +    P C+++APTREL  Q+   A ++     ++
Sbjct: 336 SGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVR 395

Query: 198 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257
           +  IYGG   G  IR + +G  I  ATPGRL+D +   K  L++  YLVLDEADRMLDMG
Sbjct: 396 AVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMG 455

Query: 258 FEPQIRKIVD----QIRPDRQTLMWSATWPKEVRQLAEDFLK-DYIHINIGALELSANHN 312
           F P+++K++       +  RQTLM+SAT+P+E+++LA +FLK +Y+ + +G +   A  +
Sbjct: 456 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRD 514

Query: 313 ILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIH 372
           + Q V       K EKL+ ++  I  E+   T+VFVETK++ D +   + ++      IH
Sbjct: 515 VQQTVLQVGQFSKREKLVEILRNIGDER---TMVFVETKKKADFIATFLCQEKISTTSIH 571

Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
           GD+ Q+ER+  L +F+ GK P+L+AT VA+RGLD+E+V+ VIN+D P++ ++Y+HRIGRT
Sbjct: 572 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 631

Query: 433 ARSTKTGTAYTFF---TPNNIKQVSDLISVLREANQAINPKLLQLVEDR----GSGRSRG 485
            R   TG A +FF   + N++ Q   L+ VL +A Q +   L ++         SG +RG
Sbjct: 632 GRCGNTGRAISFFDLESDNHLAQ--PLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRG 689

Query: 486 RGGMKDDRRDRYSAGKRGGFNTFR-----DRENYD 515
                 D R   S     GF++ +     D E++D
Sbjct: 690 NVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD 724


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score =  291 bits (746), Expect = 9e-79
 Identities = 171/455 (37%), Positives = 267/455 (58%), Gaps = 27/455 (5%)

Query: 82  ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 141
           + V GH+ P  +L F EAN    + + IA+  +T+ T +Q    P+ L+G D++  AQTG
Sbjct: 242 VEVSGHDAPPAILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTG 301

Query: 142 SGKTLSYLLPAIVHINHQPF----LERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLK 197
           SGKT ++LLP + H+ H        +    P C+++APTREL  Q+   A ++     ++
Sbjct: 302 SGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVR 361

Query: 198 STCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257
           +  IYGG   G  IR + +G  I  ATPGRL+D +   K  L++  YLVLDEADRMLDMG
Sbjct: 362 AVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEKIGLKQIKYLVLDEADRMLDMG 421

Query: 258 FEPQIRKIVD----QIRPDRQTLMWSATWPKEVRQLAEDFLK-DYIHINIGALELSANHN 312
           F P+++K++       +  RQTLM+SAT+P+E+++LA +FLK +Y+ + +G +   A  +
Sbjct: 422 FGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVGQVG-GACRD 480

Query: 313 ILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIH 372
           + Q V       K EKL+ ++  I  E+   T+VFVETK++ D +   + ++      IH
Sbjct: 481 VQQTVLQVGQFSKREKLVEILRNIGDER---TMVFVETKKKADFIATFLCQEKISTTSIH 537

Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
           GD+ Q+ER+  L +F+ GK P+L+AT VA+RGLD+E+V+ VIN+D P++ ++Y+HRIGRT
Sbjct: 538 GDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRT 597

Query: 433 ARSTKTGTAYTFF---TPNNIKQVSDLISVLREANQAINPKLLQLVEDR----GSGRSRG 485
            R   TG A +FF   + N++ Q   L+ VL +A Q +   L ++         SG +RG
Sbjct: 598 GRCGNTGRAISFFDLESDNHLAQ--PLVKVLTDAQQDVPAWLEEIAFSTYIPGFSGSTRG 655

Query: 486 RGGMKDDRRDRYSAGKRGGFNTFR-----DRENYD 515
                 D R   S     GF++ +     D E++D
Sbjct: 656 NVFASVDTRKGKSTLNTAGFSSSQAPNPVDDESWD 690


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  285 bits (730), Expect = 7e-77
 Identities = 163/455 (35%), Positives = 261/455 (57%), Gaps = 43/455 (9%)

Query: 39  EKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYE 98
           +K  K++W+       ++++ Q+  D    T ++   +R    IT +G   P P+ ++ +
Sbjct: 345 KKEAKQRWD-------DRHWSQKKLD--EMTDRDWRIFREDYSITTKGGKIPNPIRSWKD 395

Query: 99  ANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINH 158
           ++ P ++++VI +  + EPT IQ Q  P+ L   D++GVA+TGSGKT ++L+P +V I  
Sbjct: 396 SSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITT 455

Query: 159 QPFLER----GDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDL 214
            P ++R      GP  ++LAPTRELAQQ+++   ++ +   +++  + GG  +  Q   L
Sbjct: 456 LPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRL 515

Query: 215 ERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI----- 269
             G EI IATPGRLID LE     L R TY+VLDEADRM+DMGFEP ++KI++ +     
Sbjct: 516 RMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQ 575

Query: 270 RPD---------------------RQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELS 308
           +PD                     RQT+M++AT P  V +LA  +L+    + IG+    
Sbjct: 576 KPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAG-K 634

Query: 309 ANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPA 368
            +  + Q V +  + EK +KL+ ++E+     +   I+FV  K+ CD L + + + G+ A
Sbjct: 635 PHERVEQKVFLMSESEKRKKLLAILEQGF---DPPIIIFVNQKKGCDVLAKSLEKMGYNA 691

Query: 369 MGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHR 428
             +HG K Q++R++ L+  K G   IL+ATDVA RG+D++DV  V+NYD   + EDYIHR
Sbjct: 692 CTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHR 751

Query: 429 IGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREA 463
           IGRT R+ K+G A TF T  +     +L   + E+
Sbjct: 752 IGRTGRAGKSGVAITFLTKEDSAVFYELKQAILES 786


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  271 bits (694), Expect = 1e-72
 Identities = 159/409 (38%), Positives = 228/409 (55%), Gaps = 17/409 (4%)

Query: 74  ETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLD 133
           E  R+   I V G   P P+ +F E  FPA ++  + ++    PT IQ QG P  LSG D
Sbjct: 161 ERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRD 220

Query: 134 MVGVAQTGSGKTLSYLLPAIVHINHQ----PFLERGDGPICLVLAPTRELAQQVQQVAAE 189
           M+G+A TGSGKTL + LP I+    Q    PF +R +GP  L++ P+RELA+Q   +   
Sbjct: 221 MIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKR-EGPYGLIICPSRELARQTHGILEY 279

Query: 190 YCRACR------LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTT 243
           YCR  +      L+     GG     Q+  +  GV + +ATPGRL+D L+    +L    
Sbjct: 280 YCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICR 339

Query: 244 YLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIG 303
           YL LDEADRM+DMGFE  IR I    +  RQTL++SAT PK+++  A+  L   + IN+G
Sbjct: 340 YLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 399

Query: 304 ALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRR 363
               ++    L ++     V+++ K++ L+E  + +     ++F E K   D +   +  
Sbjct: 400 RAGAAS----LDVIQEVEYVKEEAKMVYLLE-CLQKTPPPVLIFAEKKADVDAIHEYLLL 454

Query: 364 DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSE 423
            G  A+ IHG K Q+ER   +  F+ GK  +L+ATDVAS+GLD   ++ VINYD P   E
Sbjct: 455 KGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIE 514

Query: 424 DYIHRIGRTARSTKTGTAYTFFTPNNIKQV-SDLISVLREANQAINPKL 471
           +Y+HRIGRT RS  TG A TF      + V  DL ++L EA Q + P L
Sbjct: 515 NYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLEAKQKVPPVL 563


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  239 bits (611), Expect = 4e-63
 Identities = 146/428 (34%), Positives = 231/428 (53%), Gaps = 15/428 (3%)

Query: 50  ELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVI 109
           E P      Y+EHP +      ++E  ++   I V+G    +P+++F   + P  +   +
Sbjct: 159 ESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFEHCSLPEVLNHNL 218

Query: 110 ARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPI 169
            +  +  PT IQ Q  PV L G D++  A TGSGKT ++LLP I+       L     P 
Sbjct: 219 KKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIMRA-----LFESKTPS 273

Query: 170 CLVLAPTRELAQQVQQVAAEYCRAC-RLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
            L+L PTRELA Q+++ A E      R+K+  + GG P  PQ+  L++ V++ IATPGRL
Sbjct: 274 ALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRL 333

Query: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288
           +D ++     L     +V+DEAD ML MGF+ Q+  I++ I  D QT++ SAT P  + Q
Sbjct: 334 LDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTILVSATIPTSIEQ 393

Query: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEK---ENKTI 345
           LA   L + + I  G   L    N+ QI+    D  K +KL     EI+++K   +   +
Sbjct: 394 LASQLLHNPVRIITGEKNLPC-ANVRQIILWVEDPAKKKKLF----EILNDKKLFKPPVL 448

Query: 346 VFVETKRRCDELTRKMRR-DGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRG 404
           VFV+ K   D L+  +++  G  ++ IH +KSQ ER  +L     G   ++++T V  RG
Sbjct: 449 VFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVVSTGVLGRG 508

Query: 405 LDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREAN 464
           LD+  V+ V+N+D P+S ++Y+H+IGR  R  + GTA TF   N+ +   D+   ++   
Sbjct: 509 LDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDIAKRVKPTG 568

Query: 465 QAINPKLL 472
             + P+LL
Sbjct: 569 SILPPQLL 576


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  214 bits (544), Expect = 2e-55
 Identities = 133/339 (39%), Positives = 192/339 (56%), Gaps = 10/339 (2%)

Query: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
           +T+PT IQ +  P+AL G D++G+A+TGSGKT ++ LP +        LE       LVL
Sbjct: 44  WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98

Query: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
            PTRELA Q+ +       +  ++S  I GG     Q   L +   I IATPGRLID LE
Sbjct: 99  TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158

Query: 234 CGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 292
             K  NLR   YLV+DEADR+L+M FE ++ KI+  I  DR+T ++SAT  K+V++L   
Sbjct: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218

Query: 293 FLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352
            LK+ +   + + +      + Q         KD  L+ ++ E+     N  ++F  T  
Sbjct: 219 ALKNPVKCAVSS-KYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG---NSFMIFCSTCN 274

Query: 353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412
                   +R  G+ A+ +HG  SQ +R   LN+FK     IL+ATDVASRGLD+  V  
Sbjct: 275 NTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDV 334

Query: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK 451
           V+N+D P  S+DYIHR+GRTAR+ ++G A TF T  +++
Sbjct: 335 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 373


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  203 bits (517), Expect = 3e-52
 Identities = 138/433 (31%), Positives = 227/433 (52%), Gaps = 29/433 (6%)

Query: 30  SGKKFGNPGEKLVKKKWNL-----DELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITV 84
           S ++   P  K +KK+  +     ++ PK +  F    PD     A   E+    ++   
Sbjct: 121 SEEEIDAPKPKKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQ--- 177

Query: 85  RGHNCPKPVLNFYEANFPAN--VMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGS 142
                P        +NFP +   + ++  +  T    IQA+ +    SG D++  A+TG+
Sbjct: 178 ---EIPVEQKEGAFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGT 234

Query: 143 GKTLSYLLPAIVHINHQ-PFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCI 201
           GKT S+ +P I  ++ +    +RG  P  LVLAPTRELA QV +  ++  +  +L   C 
Sbjct: 235 GKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITK--KLSVACF 292

Query: 202 YGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQ 261
           YGG P G Q   +  G++I + TPGR+ D ++ GK +L +  ++VLDE D+MLDMGF  Q
Sbjct: 293 YGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQ 352

Query: 262 IRKIVD-----QIRPDRQTLMWSATWPKEVRQLAEDFLKD-YIHIN-IGALELSANHNIL 314
           + +I+          + QTL++SAT P  V  +A+ ++K  Y  ++ IG         + 
Sbjct: 353 VEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVE 412

Query: 315 QIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRK--MRRDGWPAMGIH 372
            +   CH  ++   +I  +  + S  + +TI+F ETK+   EL++   +++D   A  +H
Sbjct: 413 HLAIKCHWTQR-AAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQD---AQSLH 468

Query: 373 GDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRT 432
           GD  Q++R+  L  F++G   +L+AT+VA+RGLD+ +V  VI    P   E YIHR GRT
Sbjct: 469 GDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRT 528

Query: 433 ARSTKTGTAYTFF 445
            R+ +TG    F+
Sbjct: 529 GRAGRTGVCICFY 541


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  197 bits (502), Expect = 2e-50
 Identities = 125/371 (33%), Positives = 195/371 (52%), Gaps = 8/371 (2%)

Query: 94  LNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI 153
           L+F + N    ++  I    F +PT IQ    PV L G D+   A TG+GKT ++ LP +
Sbjct: 218 LSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVL 277

Query: 154 VHINHQPFLERGDGPIC--LVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQI 211
             + ++P       P+   LVL PTREL  QV  V  +  + C + +    GG     Q 
Sbjct: 278 ERLIYKP----RQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQE 333

Query: 212 RDLERGVEICIATPGRLIDFLE-CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIR 270
             L    +I IATPGRLID L  C   +L     L+LDEADRMLD  FE Q+++I+    
Sbjct: 334 AALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCS 393

Query: 271 PDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLI 330
             RQT+++SAT   EV+ LA   LK+ + I + +    A     + + +  + E D + I
Sbjct: 394 HHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREAI 453

Query: 331 RLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHG 390
            +   +     +  ++F +TK++   +   +   G     +HG+ SQ +R   L  FK  
Sbjct: 454 -VAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDE 512

Query: 391 KAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNI 450
           +  IL+ATDVA+RGLD+E VK VIN+  PN+ + Y+HR+GRTAR+ + G + +    +  
Sbjct: 513 QIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDER 572

Query: 451 KQVSDLISVLR 461
           K + +++   +
Sbjct: 573 KMLKEIVKAAK 583


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  197 bits (501), Expect = 2e-50
 Identities = 120/365 (32%), Positives = 199/365 (54%), Gaps = 14/365 (3%)

Query: 99  ANFPAN--VMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHI 156
           +NFP +   + ++  +  T    IQ + +     G D++  A+TG+GKT S+ +P I  +
Sbjct: 140 SNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERL 199

Query: 157 N-HQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLE 215
             +Q  +++   P  LVLAPTRELA QV +   +  R  +L   C YGG     QI  + 
Sbjct: 200 QRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITR--KLSVACFYGGTSYQSQINHIR 257

Query: 216 RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQI-----R 270
            G++I + TPGR+ D L+ G+ +L +  ++VLDE D+MLD+GF  Q+  I+ +       
Sbjct: 258 NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSE 317

Query: 271 PDRQTLMWSATWPKEVRQLAEDFLKD-YIHIN-IGALELSANHNILQIVDVCHDVEKDEK 328
            + QTL++SAT P+ V ++A+ ++K  Y  ++ +G +   A   +  +   CH  ++   
Sbjct: 318 DNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAV 377

Query: 329 LIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFK 388
           +  +++ + S  E + I+F ETK+   E+          A  +HGD +Q +R+  L  F+
Sbjct: 378 IGDVLQ-VYSGSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLKGFR 435

Query: 389 HGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPN 448
            G   +L+AT+VA+RGLD+ +V  VI    P   E YIHR GRT R+ +TG    F+ P 
Sbjct: 436 EGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPR 495

Query: 449 NIKQV 453
              Q+
Sbjct: 496 ERGQL 500


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  196 bits (497), Expect = 7e-50
 Identities = 118/343 (34%), Positives = 183/343 (53%), Gaps = 8/343 (2%)

Query: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
           F +P+AIQ +     + G D++  +Q+G+GKT ++ +  +  ++ Q    +      L+L
Sbjct: 58  FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQA-----LIL 112

Query: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
           APTRELA Q+Q+          ++     GG   G  IR L+ G  +   TPGR+ D + 
Sbjct: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172

Query: 234 CGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDF 293
                 R    LVLDEAD ML+ GF+ QI  +   + P  Q ++ SAT P E+ ++   F
Sbjct: 173 RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKF 232

Query: 294 LKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRR 353
           + D I I +   EL+        V V  +  K + L  L + +      + ++F  TKR+
Sbjct: 233 MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI---TQAVIFCNTKRK 289

Query: 354 CDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFV 413
            D LT KMR   +    +HGD  Q+ER+ ++ EF+ G + +LI+TDV +RGLDV  V  +
Sbjct: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349

Query: 414 INYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456
           INYD PN+ E YIHRIGR+ R  + G A  F   ++I+ + D+
Sbjct: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  195 bits (495), Expect = 1e-49
 Identities = 126/371 (33%), Positives = 199/371 (53%), Gaps = 25/371 (6%)

Query: 95  NFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIV 154
           NF + N   +++  I    F +P+AIQ +     + G D++  AQ+G+GKT ++ +  + 
Sbjct: 34  NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 93

Query: 155 HINHQPFLERGDGPICLVLAPTRELAQQVQQVA---AEY----CRACRLKSTCIYGGAPK 207
            +  + F E       LVLAPTRELAQQ+Q+V     +Y    C AC        GG   
Sbjct: 94  QLEIE-FKETQ----ALVLAPTRELAQQIQKVILALGDYMGATCHAC-------IGGTNV 141

Query: 208 GPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIV 266
             +++ L+     I + TPGR+ D L     + +     VLDEAD ML  GF+ QI +I 
Sbjct: 142 RNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIF 201

Query: 267 DQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKD 326
            ++    Q ++ SAT P +V ++ + F++D I I +   EL+       I     +VE++
Sbjct: 202 QKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEG----IKQFYINVERE 257

Query: 327 E-KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLN 385
           E KL  L +   +    + ++F+ T+R+ D LT KM    +    +HGD  Q+ERD ++ 
Sbjct: 258 EWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMR 317

Query: 386 EFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFF 445
           EF+ G + +LI TD+ +RG+DV+ V  VINYD P + E+YIHRIGR  R  + G A  F 
Sbjct: 318 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFV 377

Query: 446 TPNNIKQVSDL 456
           T  + + + D+
Sbjct: 378 TEEDKRILRDI 388


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  193 bits (491), Expect = 3e-49
 Identities = 123/371 (33%), Positives = 196/371 (52%), Gaps = 25/371 (6%)

Query: 95  NFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIV 154
           +F + N   +++  I    F +P+AIQ +     + G D++  AQ+G+GKT ++ +  + 
Sbjct: 33  SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92

Query: 155 HINHQPFLERGDGPICLVLAPTRELAQQVQQVA---AEY----CRACRLKSTCIYGGAPK 207
            I       +      LVLAPTRELAQQ+Q+V     +Y    C AC        GG   
Sbjct: 93  QIELDLKATQA-----LVLAPTRELAQQIQKVVMALGDYMGASCHAC-------IGGTNV 140

Query: 208 GPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIV 266
             +++ L+     I + TPGR+ D L     + +     VLDEAD ML  GF+ QI  I 
Sbjct: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200

Query: 267 DQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKD 326
            ++  + Q ++ SAT P +V ++ + F++D I I +   EL+       I     +VE++
Sbjct: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEG----IRQFYINVERE 256

Query: 327 E-KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLN 385
           E KL  L +   +    + ++F+ T+R+ D LT KM    +    +HGD  Q+ERD ++ 
Sbjct: 257 EWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316

Query: 386 EFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFF 445
           EF+ G + +LI TD+ +RG+DV+ V  VINYD P + E+YIHRIGR  R  + G A    
Sbjct: 317 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376

Query: 446 TPNNIKQVSDL 456
           T  + + + D+
Sbjct: 377 TEEDKRTLRDI 387


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  191 bits (484), Expect = 2e-48
 Identities = 125/363 (34%), Positives = 189/363 (52%), Gaps = 11/363 (3%)

Query: 96  FYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVH 155
           F E    + +++   +    +PT +Q    P  L G D +G A+TGSGKT +++LP +  
Sbjct: 4   FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63

Query: 156 INHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLE 215
           ++  P+     G  CLVL PTRELA Q+ +      +   LK   I GG     Q  +L 
Sbjct: 64  LSEDPY-----GIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELS 118

Query: 216 RGVEICIATPGRLIDFLECGKT-NLRRTTYLVLDEADRMLDMG---FEPQIRKIVDQIRP 271
           R   + IATPGRL D L    T ++++  +LV+DEADR+L+ G   F   +  I+  +  
Sbjct: 119 RKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPA 178

Query: 272 DRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIR 331
            RQTL++SAT    +R+L +    +          +S    + Q   +  +  KD  L+ 
Sbjct: 179 RRQTLLFSATLTDTLREL-QGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDAYLVH 237

Query: 332 LMEEIMSEKEN-KTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHG 390
           L++    E E+   I+F  T + C  L   +R+  +P + +H    Q+ER   L +FK  
Sbjct: 238 LIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSS 297

Query: 391 KAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNI 450
              ILIATDVASRGLD+  V+ VIN++ P   + YIHR+GRTAR+ + G A T  T  +I
Sbjct: 298 IYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVTQYDI 357

Query: 451 KQV 453
             V
Sbjct: 358 HLV 360


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  185 bits (470), Expect = 9e-47
 Identities = 116/348 (33%), Positives = 182/348 (52%), Gaps = 5/348 (1%)

Query: 109 IARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGP 168
           I ++ +  PT IQ +  PV L G D+V +A+TGSGKT  +LLP    +          G 
Sbjct: 111 IMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTH---SAQTGA 167

Query: 169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
             L+L+PTRELA Q  +   E  +   LK+  I GG     Q   L    +I IATPGRL
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRL 227

Query: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288
           +         L+   Y+V DEADR+ +MGF  Q+++I+ ++    QT+++SAT PK + +
Sbjct: 228 VHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVE 287

Query: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFV 348
            A   L + + I +  ++   N  +     +  +  K   L+ L+  ++   +++T+VFV
Sbjct: 288 FARAGLTEPVLIRLD-VDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV-RPQDQTVVFV 345

Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
            TK   + LT  +         I+       R   L +F  GK   LI TD+A+RGLD+ 
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405

Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456
            +  VINY +P   + ++HR+GR AR+ ++GTAY+   P+ I  + DL
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  185 bits (470), Expect = 9e-47
 Identities = 116/348 (33%), Positives = 182/348 (52%), Gaps = 5/348 (1%)

Query: 109 IARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGP 168
           I ++ +  PT IQ +  PV L G D+V +A+TGSGKT  +LLP    +          G 
Sbjct: 111 IMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTH---SAQTGA 167

Query: 169 ICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 228
             L+L+PTRELA Q  +   E  +   LK+  I GG     Q   L    +I IATPGRL
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGRL 227

Query: 229 IDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQ 288
           +         L+   Y+V DEADR+ +MGF  Q+++I+ ++    QT+++SAT PK + +
Sbjct: 228 VHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLVE 287

Query: 289 LAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFV 348
            A   L + + I +  ++   N  +     +  +  K   L+ L+  ++   +++T+VFV
Sbjct: 288 FARAGLTEPVLIRLD-VDTKLNEQLKTSFFLVREDTKAAVLLHLLHNVV-RPQDQTVVFV 345

Query: 349 ETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVE 408
            TK   + LT  +         I+       R   L +F  GK   LI TD+A+RGLD+ 
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405

Query: 409 DVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDL 456
            +  VINY +P   + ++HR+GR AR+ ++GTAY+   P+ I  + DL
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDL 453


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  180 bits (456), Expect = 4e-45
 Identities = 122/339 (35%), Positives = 174/339 (51%), Gaps = 59/339 (17%)

Query: 114 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 173
           +T+PT IQ +  P+AL G D++G+A+TGSGKT ++ LP +        LE       LVL
Sbjct: 44  WTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPIL-----NALLETPQRLFALVL 98

Query: 174 APTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLE 233
            PTRELA Q+ +       +  ++S  I GG     Q   L +   I IATPGRLID LE
Sbjct: 99  TPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLE 158

Query: 234 CGKT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAED 292
             K  NLR   YLV+DEADR+L+M FE ++ KI+  I  DR+T ++SAT  K+V++L   
Sbjct: 159 NTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRA 218

Query: 293 FLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKR 352
            LK+ +   + +   +                              EK  +  +F+ +K 
Sbjct: 219 ALKNPVKCAVSSKYQTV-----------------------------EKLQQYYIFIPSKF 249

Query: 353 RCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412
           +   L                          LN+FK     IL+ATDVASRGLD+  V  
Sbjct: 250 KSKRLGS------------------------LNKFKAKARSILLATDVASRGLDIPHVDV 285

Query: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIK 451
           V+N+D P  S+DYIHR+GRTAR+ ++G A TF T  +++
Sbjct: 286 VVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVE 324


>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
           sapiens]
          Length = 670

 Score =  176 bits (446), Expect = 6e-44
 Identities = 109/332 (32%), Positives = 179/332 (53%), Gaps = 3/332 (0%)

Query: 104 NVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLE 163
           N +  I    FT  T IQ +     L G D++  A+TGSGKTL++L+PA+  I    F+ 
Sbjct: 189 NTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMP 248

Query: 164 RGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIA 223
           R +G   L+L+PTRELA Q   V  E           I GG+ +  + + L  G+ I +A
Sbjct: 249 R-NGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVA 307

Query: 224 TPGRLIDFLECGKTNLRRTTY-LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATW 282
           TPGRL+D ++     + +    LV+DEADR+LD+GFE ++++I+  +   RQT+++SAT 
Sbjct: 308 TPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQ 367

Query: 283 PKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKEN 342
            ++V  LA   LK    + +G  +  AN  +  +         +++ + L   +   ++ 
Sbjct: 368 TRKVEDLARISLKKE-PLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKK 426

Query: 343 KTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVAS 402
           K +VF  +          +     P + IHG + Q +R     +F +  +  L+ TDVA+
Sbjct: 427 KLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAA 486

Query: 403 RGLDVEDVKFVINYDYPNSSEDYIHRIGRTAR 434
           RGLD+ +V +++ YD P+  ++YIHR+GRTAR
Sbjct: 487 RGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR 518


>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
           [Homo sapiens]
          Length = 851

 Score =  175 bits (444), Expect = 1e-43
 Identities = 125/395 (31%), Positives = 198/395 (50%), Gaps = 58/395 (14%)

Query: 118 TAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHIN-HQPFLERGDGPICLVLAPT 176
           T++Q Q  PV L G D +  +QTGSGKTL+Y +P +  +   +  ++R DGP  LVL PT
Sbjct: 255 TSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPT 314

Query: 177 RELAQQVQQVAAEYCRACR-LKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECG 235
           RELA Q      +  +    +    + GG  +  +   L +G+ I I+TPGRL+D ++  
Sbjct: 315 RELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKST 374

Query: 236 KT-NLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPD---RQTLMWSATWPKEVRQLAE 291
           K  +  R  +LV DEADR+LD+GFE  I  I++ +  +   RQ ++ SAT  + V +LA+
Sbjct: 375 KNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLAD 434

Query: 292 DFLKDYIHINIGALELSANHNILQ-----IVDVCHDVEKDE------------------- 327
             L D + I++    L  +H+ L      + +VC     D+                   
Sbjct: 435 ISLHDPVSISV----LDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPS 490

Query: 328 --KLIRL----MEEIMSEKENKTIVFVETKRRCD-----ELTRKMRRDGWPAMG------ 370
             +L+ L    +++   E++ K +VF  +    +      L   +   G PA G      
Sbjct: 491 KLRLVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSAS 550

Query: 371 -------IHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSE 423
                  +HG   Q+ER  V  EF H +  +L+ TDVA+RGLD+  V +++ Y+ P+S  
Sbjct: 551 MRLKFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPA 610

Query: 424 DYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLIS 458
           +YIHRIGRTAR    G++     P+  + V+ L S
Sbjct: 611 EYIHRIGRTARIGCHGSSLLILAPSEAEYVNSLAS 645


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,996,273
Number of Sequences: 37866
Number of extensions: 1141498
Number of successful extensions: 3421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3135
Number of HSP's gapped (non-prelim): 166
length of query: 614
length of database: 18,247,518
effective HSP length: 108
effective length of query: 506
effective length of database: 14,157,990
effective search space: 7163942940
effective search space used: 7163942940
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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