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Search of human proteins with 4758128
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
(729 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 1456 0.0
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 959 0.0
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 955 0.0
gi|30181246 doublecortin isoform a [Homo sapiens] 508 e-144
gi|30181244 doublecortin isoform c [Homo sapiens] 506 e-143
gi|30181240 doublecortin isoform c [Homo sapiens] 506 e-143
gi|30181242 doublecortin isoform b [Homo sapiens] 504 e-143
gi|149589021 doublecortin-like kinase 3 [Homo sapiens] 321 2e-87
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 256 4e-68
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 254 2e-67
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 254 2e-67
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 252 8e-67
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 252 8e-67
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 231 1e-60
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 229 7e-60
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 222 1e-57
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 222 1e-57
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 222 1e-57
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 222 1e-57
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 222 1e-57
gi|25952118 calcium/calmodulin-dependent protein kinase II alpha... 221 1e-57
gi|25952114 calcium/calmodulin-dependent protein kinase II alpha... 221 1e-57
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
gi|26051214 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
gi|26051206 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
gi|26051216 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
gi|26051212 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
gi|26051208 calcium/calmodulin-dependent protein kinase II beta ... 218 2e-56
>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
Length = 729
Score = 1456 bits (3769), Expect = 0.0
Identities = 729/729 (100%), Positives = 729/729 (100%)
Query: 1 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR 60
MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR
Sbjct: 1 MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVR 60
Query: 61 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL 120
FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL
Sbjct: 61 FYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSL 120
Query: 121 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK 180
DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK
Sbjct: 121 DQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENK 180
Query: 181 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK 240
DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK
Sbjct: 181 DFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGK 240
Query: 241 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG 300
QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG
Sbjct: 241 QVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASSSRRSTTKSPG 300
Query: 301 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK 360
PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK
Sbjct: 301 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRSSQHGGSSTSLASTK 360
Query: 361 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI 420
VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI
Sbjct: 361 VCSSMDENDGPGEEVSEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKI 420
Query: 421 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST 480
IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST
Sbjct: 421 IKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITST 480
Query: 481 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV 540
NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV
Sbjct: 481 NKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIV 540
Query: 541 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ 600
DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ
Sbjct: 541 DGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQ 600
Query: 601 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS 660
ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS
Sbjct: 601 ILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLS 660
Query: 661 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR 720
VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR
Sbjct: 661 VAGKIKKHFNTGPKPNSTAAGVSVIALDHGFTIKRSGSLDYYQQPGMYWIRPPLLIRRGR 720
Query: 721 FSDEDATRM 729
FSDEDATRM
Sbjct: 721 FSDEDATRM 729
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 959 bits (2479), Expect = 0.0
Identities = 502/733 (68%), Positives = 589/733 (80%), Gaps = 35/733 (4%)
Query: 1 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR 45
M+ R +ELEHF+ERDK R S G + NGL PSP HSAHCSFYRTR
Sbjct: 1 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR 60
Query: 46 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV 105
TLQ LSSEKKAKK RFYRNGDRYFKG+V+AIS DRFRSF+ALL +LTR+LSDNVNLPQGV
Sbjct: 61 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV 120
Query: 106 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS 165
RTIYTIDG +K++SLD+L+EGESYVC S EPF+K++YTKN+NPNWSVN+K SRA+++
Sbjct: 121 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRALAA 179
Query: 166 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK 225
++ K SEV+E+KDFI+PKLVT+IRSGVKPRKAVRILLNKKTAHSFEQVLTDIT+AIK
Sbjct: 180 ASSVK---SEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK 236
Query: 226 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY 284
LDSGVVKRL TLDGKQV CLQDFFGDDD+FIACGPEKFRY QDDF+LD SECRV+KS SY
Sbjct: 237 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY 295
Query: 285 TKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQ 344
++ +S+ + S +KSPGPSRRSKSPAS VNGTP SQLSTP+S KS S SPTSPGS R
Sbjct: 296 SR-SSAVKYSGSKSPGPSRRSKSPAS---VNGTPSSQLSTPKSTKSSSSSPTSPGSFRGL 351
Query: 345 RSSQHGGSSTSLASTKVCSSMDENDGP-GEEVSEEGFQIPATITERYKVGRTIGDGNFAV 403
+ S HG SS+++ +G G SE +T+ E+YK+G+ IGDGNFAV
Sbjct: 352 KISAHGRSSSNVNGGPELDRCISPEGVNGNRCSES-----STLLEKYKIGKVIGDGNFAV 406
Query: 404 VKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYL 463
VKEC++RST +E+ALKII K+KC GKEH+I+NEVSILRRVKHPNI++L+EEM+ TEL+L
Sbjct: 407 VKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELFL 466
Query: 464 VMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQ 523
VMELVKGGDLFDAITS+ KYTERD S M+YNLA+A++YLH L+IVHRDIKPENLLV E+
Sbjct: 467 VMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEYP 526
Query: 524 DGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG 583
DG+KSLKLGDFGLAT+V+GPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG
Sbjct: 527 DGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCG 586
Query: 584 FPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLE 643
FPPFR + QE LFDQIL G+++FP+PYWDN++DSAKELI+ ML V+V+ R +A Q+L
Sbjct: 587 FPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQILS 646
Query: 644 HPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---ALDHGFTIKRSGSL 699
HPWV+DD EN Q V GK+K+HFN PK NST GVSVI ALD I S
Sbjct: 647 HPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKHC 706
Query: 700 DYYQQPGMYWIRP 712
+PGM I P
Sbjct: 707 QDSGRPGMEPISP 719
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 955 bits (2469), Expect = 0.0
Identities = 502/734 (68%), Positives = 589/734 (80%), Gaps = 36/734 (4%)
Query: 1 MSFGRDMELEHFDERDKAQR--------------YSRGSRVNGL-PSPTHSAHCSFYRTR 45
M+ R +ELEHF+ERDK R S G + NGL PSP HSAHCSFYRTR
Sbjct: 1 MASTRSIELEHFEERDKRPRPGSRRGAPSSSGGSSSSGPKGNGLIPSPAHSAHCSFYRTR 60
Query: 46 TLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGV 105
TLQ LSSEKKAKK RFYRNGDRYFKG+V+AIS DRFRSF+ALL +LTR+LSDNVNLPQGV
Sbjct: 61 TLQALSSEKKAKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGV 120
Query: 106 RTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSS 165
RTIYTIDG +K++SLD+L+EGESYVC S EPF+K++YTKN+NPNWSVN+K SRA+++
Sbjct: 121 RTIYTIDGSRKVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKG-GTSRALAA 179
Query: 166 LATAKGSPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIK 225
++ K SEV+E+KDFI+PKLVT+IRSGVKPRKAVRILLNKKTAHSFEQVLTDIT+AIK
Sbjct: 180 ASSVK---SEVKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIK 236
Query: 226 LDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVKSTSY 284
LDSGVVKRL TLDGKQV CLQDFFGDDD+FIACGPEKFRY QDDF+LD SECRV+KS SY
Sbjct: 237 LDSGVVKRLCTLDGKQVTCLQDFFGDDDVFIACGPEKFRYAQDDFVLDHSECRVLKS-SY 295
Query: 285 TKIASSSRRSTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQ 344
++ +S+ + S +KSPGPSRRSKSPAS VNGTP SQLSTP+S KS S SPTSPGS R
Sbjct: 296 SR-SSAVKYSGSKSPGPSRRSKSPAS---VNGTPSSQLSTPKSTKSSSSSPTSPGSFRGL 351
Query: 345 RS-SQHGGSSTSLASTKVCSSMDENDGP-GEEVSEEGFQIPATITERYKVGRTIGDGNFA 402
+ S HG SS+++ +G G SE +T+ E+YK+G+ IGDGNFA
Sbjct: 352 KQISAHGRSSSNVNGGPELDRCISPEGVNGNRCSES-----STLLEKYKIGKVIGDGNFA 406
Query: 403 VVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELY 462
VVKEC++RST +E+ALKII K+KC GKEH+I+NEVSILRRVKHPNI++L+EEM+ TEL+
Sbjct: 407 VVKECIDRSTGKEFALKIIDKAKCCGKEHLIENEVSILRRVKHPNIIMLVEEMETATELF 466
Query: 463 LVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEH 522
LVMELVKGGDLFDAITS+ KYTERD S M+YNLA+A++YLH L+IVHRDIKPENLLV E+
Sbjct: 467 LVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENLLVCEY 526
Query: 523 QDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLC 582
DG+KSLKLGDFGLAT+V+GPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLC
Sbjct: 527 PDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLC 586
Query: 583 GFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVL 642
GFPPFR + QE LFDQIL G+++FP+PYWDN++DSAKELI+ ML V+V+ R +A Q+L
Sbjct: 587 GFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQVNVEARCTAGQIL 646
Query: 643 EHPWVNDDGLPENEHQLSVAGKIKKHFNTG-PKPNSTAAGVSVI---ALDHGFTIKRSGS 698
HPWV+DD EN Q V GK+K+HFN PK NST GVSVI ALD I S
Sbjct: 647 SHPWVSDDASQENNMQAEVTGKLKQHFNNALPKQNSTTTGVSVIMNTALDKEGQIFCSKH 706
Query: 699 LDYYQQPGMYWIRP 712
+PGM I P
Sbjct: 707 CQDSGRPGMEPISP 720
>gi|30181246 doublecortin isoform a [Homo sapiens]
Length = 441
Score = 508 bits (1308), Expect = e-144
Identities = 258/352 (73%), Positives = 301/352 (85%), Gaps = 11/352 (3%)
Query: 1 MSFGRDMELE--HFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKK 58
+ F ++MEL+ HFDERDK R RGSR+NGLPSPTHSAHCSFYRTRTLQ LS+EKKAKK
Sbjct: 76 LRFHQNMELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKK 135
Query: 59 VRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKIS 118
VRFYRNGDRYFKGIVYA+S DRFRSF+ALLADLTR+LSDN+NLPQGVR IYTIDG +KI
Sbjct: 136 VRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIG 195
Query: 119 SLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRE 178
S+D+L EGESYVC S FKK+EYTKNVNPNWSVNVKT++ +A SLA++ + ++ RE
Sbjct: 196 SMDELEEGESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASS--NSAQARE 253
Query: 179 NKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLD 238
NKDF+RPKLVTIIRSGVKPRKAVR+LLNKKTAHSFEQVLTDIT+AIKL++GVVK+LYTLD
Sbjct: 254 NKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLD 313
Query: 239 GKQVMCLQDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVK----STSYTKIASSSRR 293
GKQV CL DFFGDDD+FIACGPEKFRY QDDF LDE+ECRV+K +T+ K + + ++
Sbjct: 314 GKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQK 373
Query: 294 STTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQR 345
++ KSPGP RRSKSPA S NGT SQLSTP+S +SP +PTSPGSLRK +
Sbjct: 374 TSAKSPGPMRRSKSPA--DSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHK 423
>gi|30181244 doublecortin isoform c [Homo sapiens]
Length = 360
Score = 506 bits (1302), Expect = e-143
Identities = 254/345 (73%), Positives = 296/345 (85%), Gaps = 9/345 (2%)
Query: 6 DMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNG 65
+++ HFDERDK R RGSR+NGLPSPTHSAHCSFYRTRTLQ LS+EKKAKKVRFYRNG
Sbjct: 2 ELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNG 61
Query: 66 DRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVE 125
DRYFKGIVYA+S DRFRSF+ALLADLTR+LSDN+NLPQGVR IYTIDG +KI S+D+L E
Sbjct: 62 DRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEE 121
Query: 126 GESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRP 185
GESYVC S FKK+EYTKNVNPNWSVNVKT++ +A SLA++ + ++ RENKDF+RP
Sbjct: 122 GESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASS--NSAQARENKDFVRP 179
Query: 186 KLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCL 245
KLVTIIRSGVKPRKAVR+LLNKKTAHSFEQVLTDIT+AIKL++GVVK+LYTLDGKQV CL
Sbjct: 180 KLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCL 239
Query: 246 QDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVK----STSYTKIASSSRRSTTKSPG 300
DFFGDDD+FIACGPEKFRY QDDF LDE+ECRV+K +T+ K + + ++++ KSPG
Sbjct: 240 HDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPG 299
Query: 301 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQR 345
P RRSKSPA S NGT SQLSTP+S +SP +PTSPGSLRK +
Sbjct: 300 PMRRSKSPA--DSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHK 342
>gi|30181240 doublecortin isoform c [Homo sapiens]
Length = 360
Score = 506 bits (1302), Expect = e-143
Identities = 254/345 (73%), Positives = 296/345 (85%), Gaps = 9/345 (2%)
Query: 6 DMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNG 65
+++ HFDERDK R RGSR+NGLPSPTHSAHCSFYRTRTLQ LS+EKKAKKVRFYRNG
Sbjct: 2 ELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNG 61
Query: 66 DRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVE 125
DRYFKGIVYA+S DRFRSF+ALLADLTR+LSDN+NLPQGVR IYTIDG +KI S+D+L E
Sbjct: 62 DRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEE 121
Query: 126 GESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRP 185
GESYVC S FKK+EYTKNVNPNWSVNVKT++ +A SLA++ + ++ RENKDF+RP
Sbjct: 122 GESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASS--NSAQARENKDFVRP 179
Query: 186 KLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCL 245
KLVTIIRSGVKPRKAVR+LLNKKTAHSFEQVLTDIT+AIKL++GVVK+LYTLDGKQV CL
Sbjct: 180 KLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCL 239
Query: 246 QDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVK----STSYTKIASSSRRSTTKSPG 300
DFFGDDD+FIACGPEKFRY QDDF LDE+ECRV+K +T+ K + + ++++ KSPG
Sbjct: 240 HDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPG 299
Query: 301 PSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQR 345
P RRSKSPA S NGT SQLSTP+S +SP +PTSPGSLRK +
Sbjct: 300 PMRRSKSPA--DSANGTSSSQLSTPKSKQSPISTPTSPGSLRKHK 342
>gi|30181242 doublecortin isoform b [Homo sapiens]
Length = 365
Score = 504 bits (1299), Expect = e-143
Identities = 253/348 (72%), Positives = 297/348 (85%), Gaps = 10/348 (2%)
Query: 6 DMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNG 65
+++ HFDERDK R RGSR+NGLPSPTHSAHCSFYRTRTLQ LS+EKKAKKVRFYRNG
Sbjct: 2 ELDFGHFDERDKTSRNMRGSRMNGLPSPTHSAHCSFYRTRTLQALSNEKKAKKVRFYRNG 61
Query: 66 DRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVE 125
DRYFKGIVYA+S DRFRSF+ALLADLTR+LSDN+NLPQGVR IYTIDG +KI S+D+L E
Sbjct: 62 DRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSRKIGSMDELEE 121
Query: 126 GESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGSPSEVRENKDFIRP 185
GESYVC S FKK+EYTKNVNPNWSVNVKT++ +A SLA++ + ++ RENKDF+RP
Sbjct: 122 GESYVCSSDNFFKKVEYTKNVNPNWSVNVKTSANMKAPQSLASS--NSAQARENKDFVRP 179
Query: 186 KLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCL 245
KLVTIIRSGVKPRKAVR+LLNKKTAHSFEQVLTDIT+AIKL++GVVK+LYTLDGKQV CL
Sbjct: 180 KLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLYTLDGKQVTCL 239
Query: 246 QDFFGDDDIFIACGPEKFRY-QDDFLLDESECRVVK----STSYTKIASSSRRSTTKSPG 300
DFFGDDD+FIACGPEKFRY QDDF LDE+ECRV+K +T+ K + + ++++ KSPG
Sbjct: 240 HDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAGPKASPTPQKTSAKSPG 299
Query: 301 PSRRSKSPASTSS---VNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQR 345
P RRSKSPA + + NGT SQLSTP+S +SP +PTSPGSLRK +
Sbjct: 300 PMRRSKSPADSGNDQDANGTSSSQLSTPKSKQSPISTPTSPGSLRKHK 347
>gi|149589021 doublecortin-like kinase 3 [Homo sapiens]
Length = 648
Score = 321 bits (822), Expect = 2e-87
Identities = 155/294 (52%), Positives = 212/294 (72%), Gaps = 1/294 (0%)
Query: 382 IPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILR 441
I A + + Y+ GR IGDGNFAVVKEC R T + YA+KII KS+ +GKE M+ +E+ I++
Sbjct: 348 IAANVEKHYETGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQ 407
Query: 442 RVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKY 501
+ HPNIV L E + E+YL++E V+GGDLFDAI + K+ E DA+ M+ +L A+ +
Sbjct: 408 SLSHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVH 467
Query: 502 LHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAE 561
+H +IVHRD+KPENLLV ++D S +LKL DFGLA V P++TVCGTPTYVAPEI++E
Sbjct: 468 MHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRPIFTVCGTPTYVAPEILSE 527
Query: 562 TGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAK 621
GYGL+VD+WAAGVI YILLCGFPPFR DQ+ LF+ I +G +F PYWDN+SD+AK
Sbjct: 528 KGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAK 587
Query: 622 ELITMMLLVDVDQRFSAVQVLEHPWVNDDGLPEN-EHQLSVAGKIKKHFNTGPK 674
+L++ +L+VD +R++A QVL+HPW+ G + Q V+ + HF + K
Sbjct: 588 DLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVKRQKQVSPSSEGHFRSQHK 641
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 256 bits (655), Expect = 4e-68
Identities = 133/287 (46%), Positives = 186/287 (64%), Gaps = 7/287 (2%)
Query: 386 ITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKH 445
I + Y +G G F+ V ++ T + A+K I K GKE ++NE+++L ++KH
Sbjct: 16 IRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKH 75
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + LYL+M+LV GG+LFD I YTERDAS +++ + A+KYLH L
Sbjct: 76 PNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDL 135
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVD--GPLYTVCGTPTYVAPEIIAETG 563
IVHRD+KPENLL Y + SK + + DFGL+ + D L T CGTP YVAPE++A+
Sbjct: 136 GIVHRDLKPENLLYYSLDEDSK-IMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKP 194
Query: 564 YGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKEL 623
Y VD W+ GVI YILLCG+PPF D + LF+QIL + +F SPYWD++SDSAK+
Sbjct: 195 YSKAVDCWSIGVIAYILLCGYPPFYDENDAK--LFEQILKAEYEFDSPYWDDISDSAKDF 252
Query: 624 ITMMLLVDVDQRFSAVQVLEHPWV-NDDGLPENEHQLSVAGKIKKHF 669
I ++ D ++RF+ Q L+HPW+ D L +N HQ SV+ +IKK+F
Sbjct: 253 IRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQ-SVSEQIKKNF 298
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 254 bits (650), Expect = 2e-67
Identities = 133/285 (46%), Positives = 184/285 (64%), Gaps = 4/285 (1%)
Query: 386 ITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKH 445
I+ Y++ +G G F+ V ER +A ALK I K RGKE +++NE+++LRR+ H
Sbjct: 28 ISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISH 87
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + P+ LYL MELV GG+LFD I YTE+DAS ++ + A+ YLHSL
Sbjct: 88 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 147
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG-PLYTVCGTPTYVAPEIIAETGY 564
IVHRD+KPENLL + SK + + DFGL+ I G L T CGTP YVAPE++ + Y
Sbjct: 148 GIVHRDLKPENLLYATPFEDSK-IMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPY 206
Query: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
G VD+WA GVI+YILLCG+PPF D + LF QIL +F SP+WD++S+SAK+ I
Sbjct: 207 GKAVDVWALGVISYILLCGYPPFYDESDPE--LFSQILRASYEFDSPFWDDISESAKDFI 264
Query: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHF 669
+L D +RF+ Q L H W++ D + + SV+ +I+K+F
Sbjct: 265 RHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNF 309
>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform a [Homo sapiens]
Length = 426
Score = 254 bits (650), Expect = 2e-67
Identities = 133/285 (46%), Positives = 184/285 (64%), Gaps = 4/285 (1%)
Query: 386 ITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKH 445
I+ Y++ +G G F+ V ER +A ALK I K RGKE +++NE+++LRR+ H
Sbjct: 94 ISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISH 153
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + P+ LYL MELV GG+LFD I YTE+DAS ++ + A+ YLHSL
Sbjct: 154 PNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSL 213
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG-PLYTVCGTPTYVAPEIIAETGY 564
IVHRD+KPENLL + SK + + DFGL+ I G L T CGTP YVAPE++ + Y
Sbjct: 214 GIVHRDLKPENLLYATPFEDSK-IMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPY 272
Query: 565 GLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELI 624
G VD+WA GVI+YILLCG+PPF D + LF QIL +F SP+WD++S+SAK+ I
Sbjct: 273 GKAVDVWALGVISYILLCGYPPFYDESDPE--LFSQILRASYEFDSPFWDDISESAKDFI 330
Query: 625 TMMLLVDVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHF 669
+L D +RF+ Q L H W++ D + + SV+ +I+K+F
Sbjct: 331 RHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNF 375
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 252 bits (644), Expect = 8e-67
Identities = 128/287 (44%), Positives = 186/287 (64%), Gaps = 7/287 (2%)
Query: 386 ITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKH 445
I + ++ T+G G F+ V E++T + +A+K I K +GKE I+NE+++LR++KH
Sbjct: 19 IKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKH 78
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + P LYLVM+LV GG+LFD I YTE+DAS ++ + A+ YLH +
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI--VDGPLYTVCGTPTYVAPEIIAETG 563
IVHRD+KPENLL Y QD + + DFGL+ + + T CGTP YVAPE++A+
Sbjct: 139 GIVHRDLKPENLLYYS-QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 564 YGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKEL 623
Y VD W+ GVI YILLCG+PPF D + LF+QIL + +F SPYWD++SDSAK+
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSK--LFEQILKAEYEFDSPYWDDISDSAKDF 255
Query: 624 ITMMLLVDVDQRFSAVQVLEHPWV-NDDGLPENEHQLSVAGKIKKHF 669
I ++ D ++R++ Q HPW+ D L +N H+ SV+ +I+K+F
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHE-SVSAQIRKNF 301
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 252 bits (644), Expect = 8e-67
Identities = 128/287 (44%), Positives = 186/287 (64%), Gaps = 7/287 (2%)
Query: 386 ITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKH 445
I + ++ T+G G F+ V E++T + +A+K I K +GKE I+NE+++LR++KH
Sbjct: 19 IKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKH 78
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + P LYLVM+LV GG+LFD I YTE+DAS ++ + A+ YLH +
Sbjct: 79 ENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRM 138
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATI--VDGPLYTVCGTPTYVAPEIIAETG 563
IVHRD+KPENLL Y QD + + DFGL+ + + T CGTP YVAPE++A+
Sbjct: 139 GIVHRDLKPENLLYYS-QDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKP 197
Query: 564 YGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKEL 623
Y VD W+ GVI YILLCG+PPF D + LF+QIL + +F SPYWD++SDSAK+
Sbjct: 198 YSKAVDCWSIGVIAYILLCGYPPFYDENDSK--LFEQILKAEYEFDSPYWDDISDSAKDF 255
Query: 624 ITMMLLVDVDQRFSAVQVLEHPWV-NDDGLPENEHQLSVAGKIKKHF 669
I ++ D ++R++ Q HPW+ D L +N H+ SV+ +I+K+F
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHE-SVSAQIRKNF 301
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 231 bits (590), Expect = 1e-60
Identities = 130/331 (39%), Positives = 192/331 (58%), Gaps = 13/331 (3%)
Query: 358 STKVCSSMDENDGPGEEVSEEGFQIPAT----ITERYKVGRTIGDGNFAVVKECVERSTA 413
S CSS+ + PG + I + +++ ++V +G G ++V C ++ T
Sbjct: 10 SASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQ 69
Query: 414 REYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDL 473
+ YALK++KK+ + +++ E+ +L R+ HPNI+ L E + PTE+ LV+ELV GG+L
Sbjct: 70 KPYALKVLKKTV---DKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGEL 126
Query: 474 FDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGD 533
FD I Y+ERDA+ + + A+ YLH IVHRD+KPENLL Y LK+ D
Sbjct: 127 FDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLL-YATPAPDAPLKIAD 185
Query: 534 FGLATIVDGP--LYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSG 591
FGL+ IV+ + TVCGTP Y APEI+ YG +VD+W+ G+ITYILLCGF PF
Sbjct: 186 FGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDER 245
Query: 592 DDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDG 651
DQ +F +IL + F SP+WD VS +AK+L+ ++++D +R + Q L+HPWV G
Sbjct: 246 GDQ-FMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVT--G 302
Query: 652 LPENEHQLSVAGKIKKHFNTGPKPNSTAAGV 682
N + A K + FN K + V
Sbjct: 303 KAANFVHMDTAQKKLQEFNARRKLKAAVKAV 333
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 229 bits (584), Expect = 7e-60
Identities = 119/275 (43%), Positives = 181/275 (65%), Gaps = 5/275 (1%)
Query: 396 IGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEM 455
+G G F+ V +R T + +ALK IKKS ++ ++NE+++L+++KH NIV L +
Sbjct: 29 LGSGAFSEVFLVKQRLTGKLFALKCIKKSPAF-RDSSLENEIAVLKKIKHENIVTLEDIY 87
Query: 456 DVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPE 515
+ T YLVM+LV GG+LFD I YTE+DAS ++ + SA+KYLH IVHRD+KPE
Sbjct: 88 ESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPE 147
Query: 516 NLLVYEHQDGSKSLKLGDFGLATI-VDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAG 574
NLL ++ SK + + DFGL+ + +G + T CGTP YVAPE++A+ Y VD W+ G
Sbjct: 148 NLLYLTPEENSK-IMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIG 206
Query: 575 VITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELITMMLLVDVDQ 634
VITYILLCG+PPF + + LF++I G +F SP+WD++S+SAK+ I +L D ++
Sbjct: 207 VITYILLCGYPPF--YEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNE 264
Query: 635 RFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHF 669
R++ + L HPW++ + + SV+ +I+K+F
Sbjct: 265 RYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNF 299
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 222 bits (565), Expect = 1e-57
Identities = 116/265 (43%), Positives = 167/265 (63%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ +G G F+VV+ CV++++ +EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + YLV +LV GG+LF+ I + Y+E DAS ++ + ++ ++H
Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+IVHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 DIVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKD 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 PYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A Q L+HPWV
Sbjct: 248 LINQMLTINPAKRITADQALKHPWV 272
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 222 bits (565), Expect = 1e-57
Identities = 116/265 (43%), Positives = 167/265 (63%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ +G G F+VV+ CV++++ +EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + YLV +LV GG+LF+ I + Y+E DAS ++ + ++ ++H
Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+IVHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 DIVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKD 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 PYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A Q L+HPWV
Sbjct: 248 LINQMLTINPAKRITADQALKHPWV 272
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 222 bits (565), Expect = 1e-57
Identities = 116/265 (43%), Positives = 167/265 (63%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ +G G F+VV+ CV++++ +EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + YLV +LV GG+LF+ I + Y+E DAS ++ + ++ ++H
Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+IVHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 DIVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKD 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 PYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A Q L+HPWV
Sbjct: 248 LINQMLTINPAKRITADQALKHPWV 272
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 222 bits (565), Expect = 1e-57
Identities = 116/265 (43%), Positives = 167/265 (63%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ +G G F+VV+ CV++++ +EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + YLV +LV GG+LF+ I + Y+E DAS ++ + ++ ++H
Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+IVHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 DIVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKD 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 PYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A Q L+HPWV
Sbjct: 248 LINQMLTINPAKRITADQALKHPWV 272
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 222 bits (565), Expect = 1e-57
Identities = 116/265 (43%), Positives = 167/265 (63%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ +G G F+VV+ CV++++ +EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + YLV +LV GG+LF+ I + Y+E DAS ++ + ++ ++H
Sbjct: 71 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+IVHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 DIVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKD 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 PYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A Q L+HPWV
Sbjct: 248 LINQMLTINPAKRITADQALKHPWV 272
>gi|25952118 calcium/calmodulin-dependent protein kinase II alpha
isoform 2 [Homo sapiens]
Length = 478
Score = 221 bits (564), Expect = 1e-57
Identities = 113/266 (42%), Positives = 165/266 (62%), Gaps = 7/266 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
TE Y++ +G G F+VV+ CV+ +EYA KII K ++H ++ E I R +KH
Sbjct: 10 TEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKH 69
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + YL+ +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 130 GVVHRDLKPENLLLASKLKGA-AVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKD 188
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VD+WA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK+
Sbjct: 189 PYGKPVDLWACGVILYILLVGYPPF--WDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 246
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWVN 648
LI ML ++ +R +A + L+HPW++
Sbjct: 247 LINKMLTINPSKRITAAEALKHPWIS 272
>gi|25952114 calcium/calmodulin-dependent protein kinase II alpha
isoform 1 [Homo sapiens]
Length = 489
Score = 221 bits (564), Expect = 1e-57
Identities = 113/266 (42%), Positives = 165/266 (62%), Gaps = 7/266 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
TE Y++ +G G F+VV+ CV+ +EYA KII K ++H ++ E I R +KH
Sbjct: 10 TEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLKH 69
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
PNIV L + + YL+ +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 70 PNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 129
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V+G + GTP Y++PE++ +
Sbjct: 130 GVVHRDLKPENLLLASKLKGA-AVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKD 188
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VD+WA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK+
Sbjct: 189 PYGKPVDLWACGVILYILLVGYPPF--WDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKD 246
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWVN 648
LI ML ++ +R +A + L+HPW++
Sbjct: 247 LINKMLTINPSKRITAAEALKHPWIS 272
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
>gi|26051214 calcium/calmodulin-dependent protein kinase II beta
isoform 6 [Homo sapiens]
Length = 492
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
>gi|26051206 calcium/calmodulin-dependent protein kinase II beta
isoform 2 [Homo sapiens]
Length = 542
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
>gi|26051216 calcium/calmodulin-dependent protein kinase II beta
isoform 7 [Homo sapiens]
Length = 479
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
>gi|26051212 calcium/calmodulin-dependent protein kinase II beta
isoform 5 [Homo sapiens]
Length = 503
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
>gi|26051208 calcium/calmodulin-dependent protein kinase II beta
isoform 3 [Homo sapiens]
Length = 518
Score = 218 bits (555), Expect = 2e-56
Identities = 116/265 (43%), Positives = 161/265 (60%), Gaps = 7/265 (2%)
Query: 387 TERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHM-IQNEVSILRRVKH 445
T+ Y++ IG G F+VV+ CV+ T EYA KII K ++H ++ E I R +KH
Sbjct: 11 TDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKH 70
Query: 446 PNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYLHSL 505
NIV L + + YLV +LV GG+LF+ I + Y+E DAS + + A+ + H +
Sbjct: 71 SNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQM 130
Query: 506 NIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDG---PLYTVCGTPTYVAPEIIAET 562
+VHRD+KPENLL+ G+ ++KL DFGLA V G + GTP Y++PE++ +
Sbjct: 131 GVVHRDLKPENLLLASKCKGA-AVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKE 189
Query: 563 GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE 622
YG VDIWA GVI YILL G+PPF +DQ L+ QI G DFPSP WD V+ AK
Sbjct: 190 AYGKPVDIWACGVILYILLVGYPPF--WDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKN 247
Query: 623 LITMMLLVDVDQRFSAVQVLEHPWV 647
LI ML ++ +R +A + L+HPWV
Sbjct: 248 LINQMLTINPAKRITAHEALKHPWV 272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,590,178
Number of Sequences: 37866
Number of extensions: 1354558
Number of successful extensions: 11923
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 699
Number of HSP's successfully gapped in prelim test: 489
Number of HSP's that attempted gapping in prelim test: 7603
Number of HSP's gapped (non-prelim): 2912
length of query: 729
length of database: 18,247,518
effective HSP length: 110
effective length of query: 619
effective length of database: 14,082,258
effective search space: 8716917702
effective search space used: 8716917702
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.