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Search of human proteins with 4758020
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758020 ciliary neurotrophic factor [Homo sapiens]
(200 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758020 ciliary neurotrophic factor [Homo sapiens] 406 e-114
gi|38788445 ornithine carbamoyltransferase precursor [Homo sapiens] 35 0.033
gi|219282747 KIAA1772 [Homo sapiens] 31 0.61
gi|118498362 kinectin 1 isoform b [Homo sapiens] 31 0.80
gi|118498356 kinectin 1 isoform a [Homo sapiens] 31 0.80
gi|118498368 kinectin 1 isoform c [Homo sapiens] 31 0.80
gi|33620775 kinectin 1 isoform a [Homo sapiens] 31 0.80
gi|7706379 ankyrin repeat and SOCS box-containing protein 4 isof... 31 0.80
gi|22208964 ankyrin repeat and SOCS box-containing protein 4 iso... 31 0.80
gi|216548056 cardiotrophin 1 isoform 2 [Homo sapiens] 29 3.0
gi|4503121 cardiotrophin 1 isoform 1 [Homo sapiens] 29 3.0
gi|150378520 zinc finger protein 594 [Homo sapiens] 29 3.0
gi|241982780 programmed cell death 6 interacting protein isoform... 28 4.0
gi|22027538 programmed cell death 6 interacting protein isoform ... 28 4.0
gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens] 28 5.2
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 28 6.8
gi|221316695 multimerin 2 precursor [Homo sapiens] 27 8.9
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo... 27 8.9
gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo sap... 27 8.9
>gi|4758020 ciliary neurotrophic factor [Homo sapiens]
Length = 200
Score = 406 bits (1043), Expect = e-114
Identities = 200/200 (100%), Positives = 200/200 (100%)
Query: 1 MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVAS 60
MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVAS
Sbjct: 1 MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVAS 60
Query: 61 TDQWSELTEAERLQENLQAYRTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFA 120
TDQWSELTEAERLQENLQAYRTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFA
Sbjct: 61 TDQWSELTEAERLQENLQAYRTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFA 120
Query: 121 YQIEELMILLEYKIPRNEADGMPINVGDGGLFEKKLWGLKVLQELSQWTVRSIHDLRFIS 180
YQIEELMILLEYKIPRNEADGMPINVGDGGLFEKKLWGLKVLQELSQWTVRSIHDLRFIS
Sbjct: 121 YQIEELMILLEYKIPRNEADGMPINVGDGGLFEKKLWGLKVLQELSQWTVRSIHDLRFIS 180
Query: 181 SHQTGIPARGSHYIANNKKM 200
SHQTGIPARGSHYIANNKKM
Sbjct: 181 SHQTGIPARGSHYIANNKKM 200
>gi|38788445 ornithine carbamoyltransferase precursor [Homo sapiens]
Length = 354
Score = 35.4 bits (80), Expect = 0.033
Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 29 SDLTALTESYVKHQG---LNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTFHV 85
+ +T L E Y K G L N L++A G V TD W + + E ++ LQA++ + V
Sbjct: 227 ASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQV 286
Query: 86 LL 87
+
Sbjct: 287 TM 288
>gi|219282747 KIAA1772 [Homo sapiens]
Length = 1923
Score = 31.2 bits (69), Expect = 0.61
Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 13/99 (13%)
Query: 84 HVLLARLLEDQQVHFTPTEG---------DFHQAIHTLLLQVAAFAYQIEELMILLEYKI 134
HV L ++ H P+ G + +A + L+LQV++F Y ++ +
Sbjct: 783 HVELTSVISGSLSHSEPSHGLADRVINCREVLEAFNLLVLQVSSFPYTLQTQQSRIS--- 839
Query: 135 PRNEADGMPINVG-DGGLFEKKLWGLKVLQELSQWTVRS 172
NE + ++ G D G EK +GL + QW + S
Sbjct: 840 SSNEVHWIQLDTGEDVGCEEKLYFGLSEYSKSLQWGITS 878
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 30.8 bits (68), Expect = 0.80
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 26 KIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAY---RT 82
K+R D L + G + + + A+T +L EAER E +Q+Y RT
Sbjct: 450 KLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ-AATQLKVQLQEAERRWEEVQSYIRKRT 508
Query: 83 FHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEE-LMILLEYKIPR-NEAD 140
A+ +D Q F E + Q++H+ L Q+E+ LM L+E + R N+ +
Sbjct: 509 AEHEAAQ--QDLQSKFVAKENEV-QSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Query: 141 GMPINVGD 148
+ + V D
Sbjct: 566 SLQMQVQD 573
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 30.8 bits (68), Expect = 0.80
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 26 KIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAY---RT 82
K+R D L + G + + + A+T +L EAER E +Q+Y RT
Sbjct: 450 KLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ-AATQLKVQLQEAERRWEEVQSYIRKRT 508
Query: 83 FHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEE-LMILLEYKIPR-NEAD 140
A+ +D Q F E + Q++H+ L Q+E+ LM L+E + R N+ +
Sbjct: 509 AEHEAAQ--QDLQSKFVAKENEV-QSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Query: 141 GMPINVGD 148
+ + V D
Sbjct: 566 SLQMQVQD 573
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 30.8 bits (68), Expect = 0.80
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 26 KIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAY---RT 82
K+R D L + G + + + A+T +L EAER E +Q+Y RT
Sbjct: 450 KLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ-AATQLKVQLQEAERRWEEVQSYIRKRT 508
Query: 83 FHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEE-LMILLEYKIPR-NEAD 140
A+ +D Q F E + Q++H+ L Q+E+ LM L+E + R N+ +
Sbjct: 509 AEHEAAQ--QDLQSKFVAKENEV-QSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Query: 141 GMPINVGD 148
+ + V D
Sbjct: 566 SLQMQVQD 573
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 30.8 bits (68), Expect = 0.80
Identities = 35/128 (27%), Positives = 58/128 (45%), Gaps = 9/128 (7%)
Query: 26 KIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAY---RT 82
K+R D L + G + + + A+T +L EAER E +Q+Y RT
Sbjct: 450 KLRQDYARLVNELTEKTGKLQQEEVQKKNAEQ-AATQLKVQLQEAERRWEEVQSYIRKRT 508
Query: 83 FHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEE-LMILLEYKIPR-NEAD 140
A+ +D Q F E + Q++H+ L Q+E+ LM L+E + R N+ +
Sbjct: 509 AEHEAAQ--QDLQSKFVAKENEV-QSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEE 565
Query: 141 GMPINVGD 148
+ + V D
Sbjct: 566 SLQMQVQD 573
>gi|7706379 ankyrin repeat and SOCS box-containing protein 4 isoform
a [Homo sapiens]
Length = 426
Score = 30.8 bits (68), Expect = 0.80
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 31 LTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTFHVLLARL 90
L+ L YV+H + ++N P+A W A R +E Q Y T H L+ R+
Sbjct: 187 LSELVAFYVEHGAIVDSVNAHMET--PLAIAAYW-----ALRFKE--QEYSTEHHLVCRM 237
Query: 91 LEDQQVHFTPTEGDFHQAIH 110
L D + + DF +H
Sbjct: 238 LLDYKAEVNARDDDFKSPLH 257
>gi|22208964 ankyrin repeat and SOCS box-containing protein 4
isoform b [Homo sapiens]
Length = 349
Score = 30.8 bits (68), Expect = 0.80
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 9/80 (11%)
Query: 31 LTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTFHVLLARL 90
L+ L YV+H + ++N P+A W A R +E Q Y T H L+ R+
Sbjct: 187 LSELVAFYVEHGAIVDSVNAHMET--PLAIAAYW-----ALRFKE--QEYSTEHHLVCRM 237
Query: 91 LEDQQVHFTPTEGDFHQAIH 110
L D + + DF +H
Sbjct: 238 LLDYKAEVNARDDDFKSPLH 257
>gi|216548056 cardiotrophin 1 isoform 2 [Homo sapiens]
Length = 200
Score = 28.9 bits (63), Expect = 3.0
Identities = 41/175 (23%), Positives = 64/175 (36%), Gaps = 8/175 (4%)
Query: 9 LTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTD----QW 64
L PH ++ LA + L + YV+ QG + S +PVA
Sbjct: 18 LLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPSFSPPRLPVAGLSAPAPSH 77
Query: 65 SELTEAERLQENLQAYRTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIE 124
+ L ERL+ + A LL + +Q P + + Q A +E
Sbjct: 78 AGLPVHERLRLDAAALAALPPLLDAVCR-RQAELNPRAPRLLRRLEDAARQARALGAAVE 136
Query: 125 ELMILL--EYKIPRNEADGMPINVGDG-GLFEKKLWGLKVLQELSQWTVRSIHDL 176
L+ L + PR E + G+F K+ GL+V +W R+ DL
Sbjct: 137 ALLAALGAANRGPRAEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDL 191
>gi|4503121 cardiotrophin 1 isoform 1 [Homo sapiens]
Length = 201
Score = 28.9 bits (63), Expect = 3.0
Identities = 41/175 (23%), Positives = 64/175 (36%), Gaps = 8/175 (4%)
Query: 9 LTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTD----QW 64
L PH ++ LA + L + YV+ QG + S +PVA
Sbjct: 19 LLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDPFGLPSFSPPRLPVAGLSAPAPSH 78
Query: 65 SELTEAERLQENLQAYRTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIE 124
+ L ERL+ + A LL + +Q P + + Q A +E
Sbjct: 79 AGLPVHERLRLDAAALAALPPLLDAVCR-RQAELNPRAPRLLRRLEDAARQARALGAAVE 137
Query: 125 ELMILL--EYKIPRNEADGMPINVGDG-GLFEKKLWGLKVLQELSQWTVRSIHDL 176
L+ L + PR E + G+F K+ GL+V +W R+ DL
Sbjct: 138 ALLAALGAANRGPRAEPPAATASAASATGVFPAKVLGLRVCGLYREWLSRTEGDL 192
>gi|150378520 zinc finger protein 594 [Homo sapiens]
Length = 807
Score = 28.9 bits (63), Expect = 3.0
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 2 AFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVAST 61
AF +HS LT H+R + + + T +++KHQ L+ ++ + S
Sbjct: 303 AFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRT-AFLKHQRLHAGEKIEECE--KTFSK 359
Query: 62 DQWSELTEAERLQENLQAY 80
D+ EL E +R+ + +AY
Sbjct: 360 DE--ELREEQRIHQEEKAY 376
>gi|241982780 programmed cell death 6 interacting protein isoform 2
[Homo sapiens]
Length = 873
Score = 28.5 bits (62), Expect = 4.0
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 32 TALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTFHVLLARLL 91
T + ES K +GL KNI + + + ++ + L E E L+ AY F L+A L
Sbjct: 618 TKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLRE-EVLKNLATAYDNFVELVANLK 676
Query: 92 EDQQVHFTPTE 102
E + + TE
Sbjct: 677 EGTKFYNELTE 687
>gi|22027538 programmed cell death 6 interacting protein isoform 1
[Homo sapiens]
Length = 868
Score = 28.5 bits (62), Expect = 4.0
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 32 TALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTFHVLLARLL 91
T + ES K +GL KNI + + + ++ + L E E L+ AY F L+A L
Sbjct: 613 TKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLRE-EVLKNLATAYDNFVELVANLK 671
Query: 92 EDQQVHFTPTE 102
E + + TE
Sbjct: 672 EGTKFYNELTE 682
>gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens]
Length = 1834
Score = 28.1 bits (61), Expect = 5.2
Identities = 13/40 (32%), Positives = 19/40 (47%)
Query: 158 GLKVLQELSQWTVRSIHDLRFISSHQTGIPARGSHYIANN 197
GL+V L+ W H RF+ G RGSH+ + +
Sbjct: 1015 GLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGS 1054
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 27.7 bits (60), Expect = 6.8
Identities = 34/158 (21%), Positives = 66/158 (41%), Gaps = 33/158 (20%)
Query: 24 ARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTF 83
A K+RS L ++ +S + +GLN++ SAD L+ +T
Sbjct: 86 ANKVRSKLKSIEQSIEQEEGLNRS----SAD----------------------LRIRKTQ 119
Query: 84 HVLLARLLEDQQVHFTPTEGDFHQAIHTLL---LQVAAFAYQIEELMILLEYKIPRNEAD 140
H L+R + + T+ D+ + + L++ EEL +LE P A
Sbjct: 120 HSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFAS 179
Query: 141 G--MPINVGDGGLFEKKLWGLKVLQELSQWTVRSIHDL 176
G M ++ L E + ++++ + ++R +HD+
Sbjct: 180 GIIMDSSISKQALSEIETRHSEIIK--LENSIRELHDM 215
>gi|221316695 multimerin 2 precursor [Homo sapiens]
Length = 949
Score = 27.3 bits (59), Expect = 8.9
Identities = 13/40 (32%), Positives = 22/40 (55%)
Query: 85 VLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIE 124
VLL + QVHF+P F+Q++H+L + + +E
Sbjct: 228 VLLPHVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVE 267
>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
sapiens]
Length = 423
Score = 27.3 bits (59), Expect = 8.9
Identities = 27/110 (24%), Positives = 49/110 (44%), Gaps = 20/110 (18%)
Query: 83 FH--VLLARLLEDQQVHFTPTEGDFHQAIHTLLLQV----------AAFAYQIEELMILL 130
FH V L+R D+ + F P +GDF + L QV F++ E+M+
Sbjct: 238 FHQCVRLSRFDNDRTISFIPPDGDFELMSYRLSTQVKPLIWIESVIEKFSHSRVEIMVKA 297
Query: 131 EYKIPRNE-ADGMPINV-----GDGGLFEKKLWGLKVLQELSQ--WTVRS 172
+ + + A+G+ I+V D F+ + K + E + W+++S
Sbjct: 298 KGQFKKQSVANGVEISVPVPSDADSPRFKTSVGSAKYVPERNVVIWSIKS 347
>gi|55749758 DIP2 disco-interacting protein 2 homolog B [Homo
sapiens]
Length = 1576
Score = 27.3 bits (59), Expect = 8.9
Identities = 10/20 (50%), Positives = 17/20 (85%)
Query: 41 HQGLNKNINLDSADGMPVAS 60
H+G N++ +D+ADG+PV+S
Sbjct: 252 HKGSNRSSLMDTADGVPVSS 271
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,488,976
Number of Sequences: 37866
Number of extensions: 296897
Number of successful extensions: 682
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 677
Number of HSP's gapped (non-prelim): 19
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.