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Search of human proteins with 46255052
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46255052 DNA ligase IV [Homo sapiens]
(911 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46255052 DNA ligase IV [Homo sapiens] 1851 0.0
gi|23199993 DNA ligase IV [Homo sapiens] 1851 0.0
gi|148539894 DNA ligase IV [Homo sapiens] 1851 0.0
gi|73747844 ligase III, DNA, ATP-dependent isoform beta precurso... 152 1e-36
gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precurs... 152 1e-36
gi|4557719 DNA ligase I [Homo sapiens] 124 5e-28
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ... 33 1.6
gi|239755640 PREDICTED: similar to alpha actin [Homo sapiens] 32 2.1
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 32 2.1
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li... 32 3.5
gi|20270353 tripartite motif-containing 43 [Homo sapiens] 32 3.5
>gi|46255052 DNA ligase IV [Homo sapiens]
Length = 911
Score = 1851 bits (4794), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV 60
MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV
Sbjct: 1 MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV 60
Query: 61 TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG 120
TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG
Sbjct: 61 TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG 120
Query: 121 DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA 180
DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA
Sbjct: 121 DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA 180
Query: 181 LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI 240
LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI
Sbjct: 181 LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI 240
Query: 241 TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD 300
TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD
Sbjct: 241 TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD 300
Query: 301 QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL 360
QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL
Sbjct: 301 QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL 360
Query: 361 QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE 420
QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE
Sbjct: 361 QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE 420
Query: 421 AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM 480
AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM
Sbjct: 421 AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM 480
Query: 481 SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC 540
SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC
Sbjct: 481 SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC 540
Query: 541 GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE 600
GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE
Sbjct: 541 GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE 600
Query: 601 QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE 660
QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE
Sbjct: 601 QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE 660
Query: 661 DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV 720
DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV
Sbjct: 661 DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV 720
Query: 721 VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG 780
VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG
Sbjct: 721 VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG 780
Query: 781 IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI 840
IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI
Sbjct: 781 IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI 840
Query: 841 KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK 900
KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK
Sbjct: 841 KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK 900
Query: 901 CELQEENQYLI 911
CELQEENQYLI
Sbjct: 901 CELQEENQYLI 911
>gi|23199993 DNA ligase IV [Homo sapiens]
Length = 911
Score = 1851 bits (4794), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV 60
MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV
Sbjct: 1 MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV 60
Query: 61 TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG 120
TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG
Sbjct: 61 TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG 120
Query: 121 DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA 180
DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA
Sbjct: 121 DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA 180
Query: 181 LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI 240
LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI
Sbjct: 181 LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI 240
Query: 241 TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD 300
TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD
Sbjct: 241 TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD 300
Query: 301 QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL 360
QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL
Sbjct: 301 QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL 360
Query: 361 QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE 420
QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE
Sbjct: 361 QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE 420
Query: 421 AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM 480
AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM
Sbjct: 421 AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM 480
Query: 481 SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC 540
SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC
Sbjct: 481 SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC 540
Query: 541 GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE 600
GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE
Sbjct: 541 GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE 600
Query: 601 QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE 660
QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE
Sbjct: 601 QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE 660
Query: 661 DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV 720
DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV
Sbjct: 661 DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV 720
Query: 721 VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG 780
VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG
Sbjct: 721 VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG 780
Query: 781 IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI 840
IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI
Sbjct: 781 IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI 840
Query: 841 KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK 900
KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK
Sbjct: 841 KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK 900
Query: 901 CELQEENQYLI 911
CELQEENQYLI
Sbjct: 901 CELQEENQYLI 911
>gi|148539894 DNA ligase IV [Homo sapiens]
Length = 911
Score = 1851 bits (4794), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV 60
MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV
Sbjct: 1 MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV 60
Query: 61 TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG 120
TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG
Sbjct: 61 TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG 120
Query: 121 DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA 180
DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA
Sbjct: 121 DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA 180
Query: 181 LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI 240
LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI
Sbjct: 181 LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI 240
Query: 241 TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD 300
TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD
Sbjct: 241 TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD 300
Query: 301 QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL 360
QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL
Sbjct: 301 QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL 360
Query: 361 QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE 420
QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE
Sbjct: 361 QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE 420
Query: 421 AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM 480
AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM
Sbjct: 421 AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM 480
Query: 481 SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC 540
SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC
Sbjct: 481 SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC 540
Query: 541 GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE 600
GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE
Sbjct: 541 GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE 600
Query: 601 QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE 660
QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE
Sbjct: 601 QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE 660
Query: 661 DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV 720
DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV
Sbjct: 661 DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV 720
Query: 721 VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG 780
VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG
Sbjct: 721 VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG 780
Query: 781 IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI 840
IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI
Sbjct: 781 IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI 840
Query: 841 KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK 900
KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK
Sbjct: 841 KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK 900
Query: 901 CELQEENQYLI 911
CELQEENQYLI
Sbjct: 901 CELQEENQYLI 911
>gi|73747844 ligase III, DNA, ATP-dependent isoform beta precursor
[Homo sapiens]
Length = 949
Score = 152 bits (385), Expect = 1e-36
Identities = 149/569 (26%), Positives = 260/569 (45%), Gaps = 63/569 (11%)
Query: 57 HKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPT 116
H DV Y ++L+LP + + Y + + + KL+ + N D D + L
Sbjct: 300 HGDV----YLTVKLLLPGVIKT--VYNLNDKQIVKLFSRIFNCNPD--DMARDLE----- 346
Query: 117 GTHGDAGDFAMIAYFVLKP-RCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLI 175
GD + + + K K LTIQ+V++ L ++ ++D +++L +
Sbjct: 347 --QGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSK---LTKEDEQQQALQDIA 401
Query: 176 TQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVC-RQLHDPSVG 234
++ +A + K +IR+I DLK+ + + +A E + +L+ V R LH+
Sbjct: 402 SRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEV 461
Query: 235 LSD--------ISITLFSAFKPMLA-AIADIEHIEKDMKHQSFYIETKLDGERMQMHKDG 285
+ + +L + +PMLA A +E+ K + F E K DGER+Q+HK+G
Sbjct: 462 EKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFS-EIKYDGERVQVHKNG 520
Query: 286 DVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQK 345
D + YFSR+ A +I AF + ILD E++ + T +
Sbjct: 521 DHFSYFSRSLKPVLPHKVAH-----FKDYIPQAFPGGHSM-ILDSEVLLIDNKTGKPLPF 574
Query: 346 GTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQK 405
GT + + D C VFD + N+ L L +R + L IP RI +
Sbjct: 575 GT-LGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEM 633
Query: 406 TQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVS--GLMDELD 463
+ ++ D + I + EG+++K Y+P KR WLK+K +Y++ + D D
Sbjct: 634 KRVTKALDLADMITRVIQEGLEGLVLKDVKGTYEPGKR--HWLKVKKDYLNEGAMADTAD 691
Query: 464 ILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSG---CTMKELYDLGL 520
++++G ++G+GS+GGMMS FL + PG + + T+++ G T+ L + L
Sbjct: 692 LVVLGAFYGQGSKGGMMSIFLMGCYD---PGSQK--WCTVTKCAGGHDDATLARLQN-EL 745
Query: 521 KLAKYWKPFHRKAPPSSILCGTEKPEVYI------EPCNSVIVQIKAAEIVPSDMYKT-G 573
+ K K PS I + ++Y +P + + +I AE S+ + G
Sbjct: 746 DMVKISK------DPSKIPSWLKVNKIYYPDFIVPDPKKAAVWEITGAEFSKSEAHTADG 799
Query: 574 CTLRFPRIEKIRDDKEWHECMTLDDLEQL 602
++RFPR +IRDDK+W L L++L
Sbjct: 800 ISIRFPRCTRIRDDKDWKSATNLPQLKEL 828
>gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precursor
[Homo sapiens]
Length = 1009
Score = 152 bits (385), Expect = 1e-36
Identities = 149/569 (26%), Positives = 260/569 (45%), Gaps = 63/569 (11%)
Query: 57 HKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPT 116
H DV Y ++L+LP + + Y + + + KL+ + N D D + L
Sbjct: 300 HGDV----YLTVKLLLPGVIKT--VYNLNDKQIVKLFSRIFNCNPD--DMARDLE----- 346
Query: 117 GTHGDAGDFAMIAYFVLKP-RCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLI 175
GD + + + K K LTIQ+V++ L ++ ++D +++L +
Sbjct: 347 --QGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSK---LTKEDEQQQALQDIA 401
Query: 176 TQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVC-RQLHDPSVG 234
++ +A + K +IR+I DLK+ + + +A E + +L+ V R LH+
Sbjct: 402 SRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEV 461
Query: 235 LSD--------ISITLFSAFKPMLA-AIADIEHIEKDMKHQSFYIETKLDGERMQMHKDG 285
+ + +L + +PMLA A +E+ K + F E K DGER+Q+HK+G
Sbjct: 462 EKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFS-EIKYDGERVQVHKNG 520
Query: 286 DVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQK 345
D + YFSR+ A +I AF + ILD E++ + T +
Sbjct: 521 DHFSYFSRSLKPVLPHKVAH-----FKDYIPQAFPGGHSM-ILDSEVLLIDNKTGKPLPF 574
Query: 346 GTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQK 405
GT + + D C VFD + N+ L L +R + L IP RI +
Sbjct: 575 GT-LGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEM 633
Query: 406 TQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVS--GLMDELD 463
+ ++ D + I + EG+++K Y+P KR WLK+K +Y++ + D D
Sbjct: 634 KRVTKALDLADMITRVIQEGLEGLVLKDVKGTYEPGKR--HWLKVKKDYLNEGAMADTAD 691
Query: 464 ILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSG---CTMKELYDLGL 520
++++G ++G+GS+GGMMS FL + PG + + T+++ G T+ L + L
Sbjct: 692 LVVLGAFYGQGSKGGMMSIFLMGCYD---PGSQK--WCTVTKCAGGHDDATLARLQN-EL 745
Query: 521 KLAKYWKPFHRKAPPSSILCGTEKPEVYI------EPCNSVIVQIKAAEIVPSDMYKT-G 573
+ K K PS I + ++Y +P + + +I AE S+ + G
Sbjct: 746 DMVKISK------DPSKIPSWLKVNKIYYPDFIVPDPKKAAVWEITGAEFSKSEAHTADG 799
Query: 574 CTLRFPRIEKIRDDKEWHECMTLDDLEQL 602
++RFPR +IRDDK+W L L++L
Sbjct: 800 ISIRFPRCTRIRDDKDWKSATNLPQLKEL 828
>gi|4557719 DNA ligase I [Homo sapiens]
Length = 919
Score = 124 bits (310), Expect = 5e-28
Identities = 109/379 (28%), Positives = 175/379 (46%), Gaps = 36/379 (9%)
Query: 247 KPMLA-AIADIEHIEKDMKHQSFYIETKLDGERMQMHK-DGDVYKYFSRNGYNYTDQFGA 304
KPMLA I + K + +F E K DG+R Q+H +G K FSRN D G
Sbjct: 541 KPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRN---QEDNTGK 597
Query: 305 SPTEGSLTPFIHNAFKADIQICILDGEMMAYN---PNTQTFMQKGTKFDIKRMVEDSDLQ 361
P S P I + ILD E +A++ Q F T+ + + +Q
Sbjct: 598 YPDIISRIPKIK---LPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQ 654
Query: 362 TCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKN--EVIDALN 419
C FD++ +N + L E L +R ++L F G E V T TK+ ++ + L
Sbjct: 655 VCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEG--EFVFATSLDTKDIEQIAEFLE 712
Query: 420 EAIDKREEGIMVK--QPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRG 477
+++ EG+MVK + Y+ KR WLK+K +Y+ G+ D LD++++G Y G+G R
Sbjct: 713 QSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRA 772
Query: 478 GMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSS 537
G FL A + E + ++G+G + +EL + L P R P
Sbjct: 773 GRYGGFLLASYD-----EDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPR---PYV 824
Query: 538 ILCGTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKT---------GCTLRFPRIEKIRDDK 588
+ G P+ +++P S + ++K A++ S +Y G +LRFPR ++R+DK
Sbjct: 825 RIDGAVIPDHWLDP--SAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDK 882
Query: 589 EWHECMTLDDLEQLRGKAS 607
+ + T + L K S
Sbjct: 883 QPEQATTSAQVACLYRKQS 901
>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
[Homo sapiens]
Length = 1235
Score = 32.7 bits (73), Expect = 1.6
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 5/94 (5%)
Query: 190 IIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPM 249
++++LK+ Q +F ++HN+ ++H + T LE V R L LS + + K
Sbjct: 212 LLEELKMNKIQLQLFQLYHNE-KKIHLLNTKLEHVNRDLSVKRESLSHHENIVKARKKEH 270
Query: 250 LAAIADIEHIEKDMKHQSFYIETKLDGERMQMHK 283
++ EK++K +ET L+ +R Q K
Sbjct: 271 GMLTRQLQQTEKELKS----VETLLNQKRPQYIK 300
>gi|239755640 PREDICTED: similar to alpha actin [Homo sapiens]
Length = 369
Score = 32.3 bits (72), Expect = 2.1
Identities = 35/128 (27%), Positives = 52/128 (40%), Gaps = 16/128 (12%)
Query: 249 MLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYT---DQF--- 302
+L D E+I +DMK + Y+ D E+M+ KY +G T + F
Sbjct: 197 LLVGTGDREYI-RDMKEKCCYVALDFDKEKMKTDSPSCQQKYQLPDGQEITVGQESFFCP 255
Query: 303 GASPTEGSLTPFIHNAFKADIQIC------ILDGEMMAYNPNTQTFMQKGTKFDIKRMVE 356
A TEG TP IH I C +L G M+ + T G +F ++R +
Sbjct: 256 EARGTEGKNTPGIHTKAIQSITSCNPDLQKVLFGHMLL---SGGTGSCPGLRFRMQREIS 312
Query: 357 DSDLQTCY 364
+ T Y
Sbjct: 313 ELVSPTVY 320
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 32.3 bits (72), Expect = 2.1
Identities = 22/109 (20%), Positives = 52/109 (47%), Gaps = 10/109 (9%)
Query: 198 VSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVG-LSDISITLFSAFKPMLAAIADI 256
+S Q + ++ ++D ++ T+ ++ + DP+ L +S+ L +K I ++
Sbjct: 48 ISDQQVSALSYSD--QIQQPLTNQRRMPQTFRDPATAPLRKLSVDLIKTYKH----INEV 101
Query: 257 EHIEKDMKHQSFYIETKLDGERMQMHKDG---DVYKYFSRNGYNYTDQF 302
+ +K +HQ + + +++ DG D Y Y +NG + D++
Sbjct: 102 YYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRY 150
>gi|88953346 PREDICTED: Tripartite motif-containing protein 43-like
protein 1 [Homo sapiens]
Length = 446
Score = 31.6 bits (70), Expect = 3.5
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
Query: 32 RAEKIRHFREFLDSWRKFHDALHKNHKDVTDSFYPAMRLILPQLERERMAYGIKETMLAK 91
RA+ IR+ +RK H LHK K + + I QL+R + K L +
Sbjct: 175 RAQMIRN------EYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKE 228
Query: 92 LYIELLNL 99
+Y EL+ +
Sbjct: 229 MYQELMEM 236
>gi|20270353 tripartite motif-containing 43 [Homo sapiens]
Length = 446
Score = 31.6 bits (70), Expect = 3.5
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
Query: 32 RAEKIRHFREFLDSWRKFHDALHKNHKDVTDSFYPAMRLILPQLERERMAYGIKETMLAK 91
RA+ IR+ +RK H LHK K + + I QL+R + K L +
Sbjct: 175 RAQMIRN------EYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKE 228
Query: 92 LYIELLNL 99
+Y EL+ +
Sbjct: 229 MYQELMEM 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,880,563
Number of Sequences: 37866
Number of extensions: 1582489
Number of successful extensions: 3594
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3575
Number of HSP's gapped (non-prelim): 12
length of query: 911
length of database: 18,247,518
effective HSP length: 111
effective length of query: 800
effective length of database: 14,044,392
effective search space: 11235513600
effective search space used: 11235513600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.