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Search of human proteins with 4557882
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557882 interleukin 2 receptor, gamma precursor [Homo
sapiens]
(369 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens] 782 0.0
gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo sap... 82 1e-15
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi... 70 3e-12
gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo sapi... 65 1e-10
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 57 3e-08
gi|20070195 colony stimulating factor 2 receptor alpha chain iso... 57 3e-08
gi|238908519 colony stimulating factor 2 receptor alpha chain is... 57 3e-08
gi|238908515 colony stimulating factor 2 receptor alpha chain is... 57 3e-08
gi|27437032 colony stimulating factor 2 receptor alpha chain iso... 57 3e-08
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H... 52 7e-07
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H... 52 7e-07
gi|238908517 colony stimulating factor 2 receptor alpha chain is... 51 1e-06
gi|27437036 colony stimulating factor 2 receptor alpha chain iso... 50 2e-06
gi|27437034 colony stimulating factor 2 receptor alpha chain iso... 47 4e-05
gi|238908521 colony stimulating factor 2 receptor alpha chain is... 46 6e-05
gi|4503591 erythropoietin receptor precursor [Homo sapiens] 44 2e-04
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 44 3e-04
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 44 3e-04
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 44 3e-04
gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens] 42 9e-04
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 41 0.001
gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [H... 40 0.004
gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [H... 40 0.004
gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [H... 40 0.004
gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [H... 40 0.004
gi|27437040 colony stimulating factor 2 receptor alpha chain iso... 40 0.004
gi|28610149 interleukin 6 signal transducer isoform 2 precursor ... 39 0.006
gi|4557669 interleukin 4 receptor alpha chain isoform a precurso... 38 0.013
gi|110349719 titin isoform N2-A [Homo sapiens] 36 0.048
gi|110349717 titin isoform novex-2 [Homo sapiens] 36 0.048
>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
Length = 369
Score = 782 bits (2020), Expect = 0.0
Identities = 369/369 (100%), Positives = 369/369 (100%)
Query: 1 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV 60
MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV
Sbjct: 1 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV 60
Query: 61 QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK 120
QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK
Sbjct: 61 QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK 120
Query: 121 EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN 180
EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN
Sbjct: 121 EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN 180
Query: 181 HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW 240
HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW
Sbjct: 181 HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW 240
Query: 241 SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV 300
SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV
Sbjct: 241 SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV 300
Query: 301 TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP 360
TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP
Sbjct: 301 TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP 360
Query: 361 PCYTLKPET 369
PCYTLKPET
Sbjct: 361 PCYTLKPET 369
>gi|10834992 interleukin 13 receptor, alpha 2 precursor [Homo
sapiens]
Length = 380
Score = 81.6 bits (200), Expect = 1e-15
Identities = 65/251 (25%), Positives = 111/251 (44%), Gaps = 18/251 (7%)
Query: 31 NGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSS-SEPQPTNLTLHY 89
NG+E + + TT + + ++ C +N +Y+ C+W TN L Y
Sbjct: 115 NGSE-VQSSWAETTYWISPQGIPETKVQDMDCVYYNWQYLLCSWKPGIGVLLDTNYNLFY 173
Query: 90 WYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPRE--PRRQATQMLK 147
WY+ D+ +C Y+ ++ GC+ E Y+ F + + E P R + +
Sbjct: 174 WYEGLDH--ALQCVDYIKADGQNIGCRFPYLEASDYKDFYICVNGSSENKPIRSSYFTFQ 231
Query: 148 LQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDY 204
LQN+V P P LT + S +++L W+ C ++ ++ R D D + +V+
Sbjct: 232 LQNIVKPLPPVYLTFTRESSCEIKLKWSIPLGPIPARCFDYEIEIRED-DTTLVTATVE- 289
Query: 205 RHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHW-GSNTSKEN------PFL 257
++L + + ++ F VRS+ N C WSEWS W G + SK+ PF
Sbjct: 290 NETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDKQCWEGEDLSKKTLLRFWLPFG 349
Query: 258 FALEAVVISVG 268
F L V+ G
Sbjct: 350 FILILVIFVTG 360
>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
sapiens]
Length = 427
Score = 70.1 bits (170), Expect = 3e-12
Identities = 65/243 (26%), Positives = 107/243 (44%), Gaps = 33/243 (13%)
Query: 59 EVQCFVFNVEYMNCTWNSSSEPQP-TNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGC-- 115
E+QC N+ YM C+W P TN TL+YW+++ +K+ +C + +F E GC
Sbjct: 131 ELQCIWHNLSYMKCSWLPGRNTSPDTNYTLYYWHRSL--EKIHQCEN-IFREGQYFGCSF 187
Query: 116 QLQKKEIHLYQTFVVQL--QDPREPRRQATQMLKLQNLVIPWAP--ENLTLHKLSESQLE 171
L K + ++ VQ+ +D + + ++ L + V P P +NL+ H L
Sbjct: 188 DLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPHIKNLSFH---NDDLY 244
Query: 172 LNWNN--RFLNHCLEHLVQYRTDWDHSWT--------------EQSVDYRHKFSLPSVDG 215
+ W N F++ CL + V+ + E++V+ F +P V
Sbjct: 245 VQWENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVPGVLP 304
Query: 216 QKRYTFRVRSRFNPLC-GSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMGLII 274
T R+R + N LC + WS WS + G K N L+ +++ V G II
Sbjct: 305 DTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIG---KKRNSTLYITMLLIVPVIVAGAII 361
Query: 275 SLL 277
LL
Sbjct: 362 VLL 364
>gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo
sapiens]
Length = 371
Score = 64.7 bits (156), Expect = 1e-10
Identities = 67/269 (24%), Positives = 128/269 (47%), Gaps = 30/269 (11%)
Query: 59 EVQCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQL- 117
++Q FN+E + TWN+S + TNLT HY + ++ +C++YL E TSGC L
Sbjct: 31 QIQIIYFNLETVQVTWNASKYSR-TNLTFHYRFNG--DEAYDQCTNYLLQEGHTSGCLLD 87
Query: 118 -QKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNN 176
++++ LY +++ P A++ + + P +P+++ + S Q +
Sbjct: 88 AEQRDDILY----FSIRNGTHPVFTASRWMVY--YLKPSSPKHV---RFSWHQDAVTVTC 138
Query: 177 RFLNH-CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSR-FNPLCGSA 234
L++ L + VQYR+ +D W + + ++ +D +K Y+F VR + + G
Sbjct: 139 SDLSYGDLLYEVQYRSPFDTEW-QSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPD 197
Query: 235 QHWSEWSHPIHWGSNTSKE-------NPFLFALEAVVISVGSMGLIISLLCVYFW----- 282
+ S+WS W ++ P + ++IS ++ L++SLL + W
Sbjct: 198 TYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSKFILISSLAILLMVSLLLLSLWKLWRV 257
Query: 283 LERTMPRIPTLKNLEDLVTEYH-GNFSAW 310
+ +P +P K++ + E H GNF W
Sbjct: 258 KKFLIPSVPDPKSIFPGLFEIHQGNFQEW 286
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 57.0 bits (136), Expect = 3e-08
Identities = 54/203 (26%), Positives = 89/203 (43%), Gaps = 24/203 (11%)
Query: 60 VQCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLF----SEEITSGC 115
++CF ++C+W E ++++ +YK S + ++CS L S C
Sbjct: 248 LECFFDGAAVLSCSWEVRKEVA-SSVSFGLFYKPSPDAGEEECSPVLREGLGSLHTRHHC 306
Query: 116 QLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN 175
Q+ + + ++V +Q PRR + N I AP +L + K +S L W
Sbjct: 307 QIPVPDPATHGQYIVSVQ----PRRAEKHIKSSVN--IQMAPPSLNVTKDGDSY-SLRWE 359
Query: 176 NRFLNHCLEHL-----VQYRTD---WDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRF 227
+ + EH+ +QYR D W S TE ++ H +LP+++ RY RVR R
Sbjct: 360 TMKMRY--EHIDHTFEIQYRKDTATWKDSKTE-TLQNAHSMALPALEPSTRYWARVRVR- 415
Query: 228 NPLCGSAQHWSEWSHPIHWGSNT 250
G WSEWS W + +
Sbjct: 416 TSRTGYNGIWSEWSEARSWDTES 438
>gi|20070195 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 57.0 bits (136), Expect = 3e-08
Identities = 57/287 (19%), Positives = 114/287 (39%), Gaps = 39/287 (13%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRR 140
P ++ + +NS + +C +Y+ GC L + + + RE
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGI 203
Query: 141 QATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQYRTDWDHSWTE 199
Q L + + P + + + + + W L +L QY+ D T+
Sbjct: 204 QFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQ 263
Query: 200 Q---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNT 250
S D ++++ PS + + +++ ++R+ + +WS WS I +GS+
Sbjct: 264 PGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSSWSEAIEFGSDD 319
Query: 251 SK-ENPFLFALEAVVISVGSMGLIISLLCVYFW-LERTMPRIPTLKN 295
+ +++ L +++ G+++ L F ++R P +P +K+
Sbjct: 320 GNLGSVYIYVL--LIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKD 364
>gi|238908519 colony stimulating factor 2 receptor alpha chain
isoform g precursor [Homo sapiens]
Length = 410
Score = 57.0 bits (136), Expect = 3e-08
Identities = 57/287 (19%), Positives = 114/287 (39%), Gaps = 39/287 (13%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRR 140
P ++ + +NS + +C +Y+ GC L + + + RE
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGI 203
Query: 141 QATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQYRTDWDHSWTE 199
Q L + + P + + + + + W L +L QY+ D T+
Sbjct: 204 QFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQ 263
Query: 200 Q---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNT 250
S D ++++ PS + + +++ ++R+ + +WS WS I +GS+
Sbjct: 264 PGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSSWSEAIEFGSDD 319
Query: 251 SK-ENPFLFALEAVVISVGSMGLIISLLCVYFW-LERTMPRIPTLKN 295
+ +++ L +++ G+++ L F ++R P +P +K+
Sbjct: 320 GNLGSVYIYVL--LIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKD 364
>gi|238908515 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 57.0 bits (136), Expect = 3e-08
Identities = 57/287 (19%), Positives = 114/287 (39%), Gaps = 39/287 (13%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRR 140
P ++ + +NS + +C +Y+ GC L + + + RE
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGI 203
Query: 141 QATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQYRTDWDHSWTE 199
Q L + + P + + + + + W L +L QY+ D T+
Sbjct: 204 QFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQ 263
Query: 200 Q---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNT 250
S D ++++ PS + + +++ ++R+ + +WS WS I +GS+
Sbjct: 264 PGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSSWSEAIEFGSDD 319
Query: 251 SK-ENPFLFALEAVVISVGSMGLIISLLCVYFW-LERTMPRIPTLKN 295
+ +++ L +++ G+++ L F ++R P +P +K+
Sbjct: 320 GNLGSVYIYVL--LIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKD 364
>gi|27437032 colony stimulating factor 2 receptor alpha chain
isoform a precursor [Homo sapiens]
Length = 400
Score = 57.0 bits (136), Expect = 3e-08
Identities = 57/287 (19%), Positives = 114/287 (39%), Gaps = 39/287 (13%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRR 140
P ++ + +NS + +C +Y+ GC L + + + RE
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGI 203
Query: 141 QATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQYRTDWDHSWTE 199
Q L + + P + + + + + W L +L QY+ D T+
Sbjct: 204 QFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQ 263
Query: 200 Q---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNT 250
S D ++++ PS + + +++ ++R+ + +WS WS I +GS+
Sbjct: 264 PGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSSWSEAIEFGSDD 319
Query: 251 SK-ENPFLFALEAVVISVGSMGLIISLLCVYFW-LERTMPRIPTLKN 295
+ +++ L +++ G+++ L F ++R P +P +K+
Sbjct: 320 GNLGSVYIYVL--LIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKD 364
>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 52.4 bits (124), Expect = 7e-07
Identities = 57/241 (23%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Query: 70 MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124
++CTW ++ P+ T L+Y Y S ++ Q+ S I C + I
Sbjct: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
Query: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181
+ +V R Q+ L + P N+T ++ ++L + W + F H
Sbjct: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
Query: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241
C ++ V+ + + + S+ +D +Y +VR+ + +C A WSEWS
Sbjct: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
Query: 242 HPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLC--VYFWLERTMPRIPTLK-NLED 298
PI+ G++ K F + ++ ++ + LI+SL+C + W+ + P IP K N++D
Sbjct: 327 QPIYVGNDEHKPLREWFVI-VIMATICFILLILSLICKICHLWI-KLFPPIPAPKSNIKD 384
Query: 299 L 299
L
Sbjct: 385 L 385
>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 52.4 bits (124), Expect = 7e-07
Identities = 57/241 (23%), Positives = 107/241 (44%), Gaps = 19/241 (7%)
Query: 70 MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124
++CTW ++ P+ T L+Y Y S ++ Q+ S I C + I
Sbjct: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
Query: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181
+ +V R Q+ L + P N+T ++ ++L + W + F H
Sbjct: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
Query: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241
C ++ V+ + + + S+ +D +Y +VR+ + +C A WSEWS
Sbjct: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
Query: 242 HPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLC--VYFWLERTMPRIPTLK-NLED 298
PI+ G++ K F + ++ ++ + LI+SL+C + W+ + P IP K N++D
Sbjct: 327 QPIYVGNDEHKPLREWFVI-VIMATICFILLILSLICKICHLWI-KLFPPIPAPKSNIKD 384
Query: 299 L 299
L
Sbjct: 385 L 385
>gi|238908517 colony stimulating factor 2 receptor alpha chain
isoform f precursor [Homo sapiens]
Length = 434
Score = 51.2 bits (121), Expect = 1e-06
Identities = 49/240 (20%), Positives = 92/240 (38%), Gaps = 35/240 (14%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRR 140
P ++ + +NS + +C +Y+ GC L + + + RE
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGI 203
Query: 141 QATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQYRTDWDHSWTE 199
Q L + + P + + + + + W L +L QY+ D T+
Sbjct: 204 QFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQ 263
Query: 200 Q---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNT 250
S D ++++ PS + + +++ ++R+ + +WS WS I +GS++
Sbjct: 264 PGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSSWSEAIEFGSHS 319
>gi|27437036 colony stimulating factor 2 receptor alpha chain
isoform c precursor [Homo sapiens]
Length = 333
Score = 50.4 bits (119), Expect = 2e-06
Identities = 49/238 (20%), Positives = 90/238 (37%), Gaps = 35/238 (14%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRR 140
P ++ + +NS + +C +Y+ GC L + + + RE
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGI 203
Query: 141 QATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQYRTDWDHSWTE 199
Q L + + P + + + + + W L +L QY+ D T+
Sbjct: 204 QFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQ 263
Query: 200 Q---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGS 248
S D ++++ PS + + +++ ++R+ + +WS WS I +GS
Sbjct: 264 PGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSSWSEAIEFGS 317
>gi|27437034 colony stimulating factor 2 receptor alpha chain
isoform b precursor [Homo sapiens]
Length = 377
Score = 46.6 bits (109), Expect = 4e-05
Identities = 47/236 (19%), Positives = 88/236 (37%), Gaps = 35/236 (14%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVVQLQDPREPRR 140
P ++ + +NS + +C +Y+ GC L + + + RE
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLVNGTSREIGI 203
Query: 141 QATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQYRTDWDHSWTE 199
Q L + + P + + + + + W L +L QY+ D T+
Sbjct: 204 QFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQLDVHRKNTQ 263
Query: 200 Q---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHW 246
S D ++++ PS + + +++ ++R+ + +WS WS I +
Sbjct: 264 PGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSSWSEAIEF 315
>gi|238908521 colony stimulating factor 2 receptor alpha chain
isoform h [Homo sapiens]
Length = 267
Score = 45.8 bits (107), Expect = 6e-05
Identities = 45/238 (18%), Positives = 98/238 (41%), Gaps = 19/238 (7%)
Query: 70 MNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFV 129
MNCTW + P ++ + +NS + +C +Y+ GC L + +
Sbjct: 1 MNCTW-ARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYF 59
Query: 130 VQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLNHCLEHL-VQ 188
+ RE Q L + + P + + + + + W L +L Q
Sbjct: 60 LVNGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQ 119
Query: 189 YRTDWDHSWTEQ---------SVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSE 239
Y+ D T+ S D ++++ PS + + +++ ++R+ + +WS
Sbjct: 120 YQLDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRIL----NWSS 175
Query: 240 WSHPIHWGSNTSK-ENPFLFALEAVVISVGSMGLIISLLCVYFW-LERTMPRIPTLKN 295
WS I +GS+ + +++ L +++ G+++ L F ++R P +P +K+
Sbjct: 176 WSEAIEFGSDDGNLGSVYIYVL--LIVGTLVCGIVLGFLFKRFLRIQRLFPPVPQIKD 231
>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
Length = 508
Score = 43.9 bits (102), Expect = 2e-04
Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 210 LPSVDGQKRYTFRVRSRF-NPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVG 268
L ++ G+ RYTF VR+R P G WS WS P+ S +P + L +++ +
Sbjct: 207 LSNLRGRTRYTFAVRARMAEPSFGG--FWSAWSEPVSL-LTPSDLDPLILTLSLILVVIL 263
Query: 269 SMGLIISLLCVYFWL-ERTMPRIPTLKN-LEDLVTEYHGNFSAW 310
+ +++LL L ++ P IP+ ++ E L T + GNF W
Sbjct: 264 VLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLW 307
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 43.5 bits (101), Expect = 3e-04
Identities = 57/234 (24%), Positives = 96/234 (41%), Gaps = 34/234 (14%)
Query: 58 PEVQCFVFNVEYMNCT---WNSSSEPQPTNLTLHYWYKNSD-NDKVQKCSHYLFSEEITS 113
P++ C+ ++ + C WN P+ LTL + + + D+ CS + + T
Sbjct: 21 PDLVCYTDYLQTVICILEMWNL----HPSTLTLTWQDQYEELKDEATSCSLHRSAHNATH 76
Query: 114 G---CQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQL 170
C + F V + D Q L + P P N+T+ Q
Sbjct: 77 ATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQY 134
Query: 171 ELNWNNRF-------LNHCLEHLVQYRTDWDHSWTEQ------SVDYRHKFSLPSVDGQK 217
++W + + L L++ +QYR D W SVD R LP ++ +K
Sbjct: 135 NISWRSDYEDPAFYMLKGKLQYELQYRNRGD-PWAVSPRRKLISVDSRSVSLLP-LEFRK 192
Query: 218 RYTFRVRSRFNPLCGSAQH--WSEWSHPIHWGSNTS--KE--NPFLFALEAVVI 265
++ ++ R P+ GS+ WSEWS P+ + + + KE NP L L +VI
Sbjct: 193 DSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVI 246
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 43.5 bits (101), Expect = 3e-04
Identities = 57/234 (24%), Positives = 96/234 (41%), Gaps = 34/234 (14%)
Query: 58 PEVQCFVFNVEYMNCT---WNSSSEPQPTNLTLHYWYKNSD-NDKVQKCSHYLFSEEITS 113
P++ C+ ++ + C WN P+ LTL + + + D+ CS + + T
Sbjct: 21 PDLVCYTDYLQTVICILEMWNL----HPSTLTLTWQDQYEELKDEATSCSLHRSAHNATH 76
Query: 114 G---CQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQL 170
C + F V + D Q L + P P N+T+ Q
Sbjct: 77 ATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQY 134
Query: 171 ELNWNNRF-------LNHCLEHLVQYRTDWDHSWTEQ------SVDYRHKFSLPSVDGQK 217
++W + + L L++ +QYR D W SVD R LP ++ +K
Sbjct: 135 NISWRSDYEDPAFYMLKGKLQYELQYRNRGD-PWAVSPRRKLISVDSRSVSLLP-LEFRK 192
Query: 218 RYTFRVRSRFNPLCGSAQH--WSEWSHPIHWGSNTS--KE--NPFLFALEAVVI 265
++ ++ R P+ GS+ WSEWS P+ + + + KE NP L L +VI
Sbjct: 193 DSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVI 246
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 43.5 bits (101), Expect = 3e-04
Identities = 57/234 (24%), Positives = 96/234 (41%), Gaps = 34/234 (14%)
Query: 58 PEVQCFVFNVEYMNCT---WNSSSEPQPTNLTLHYWYKNSD-NDKVQKCSHYLFSEEITS 113
P++ C+ ++ + C WN P+ LTL + + + D+ CS + + T
Sbjct: 21 PDLVCYTDYLQTVICILEMWNL----HPSTLTLTWQDQYEELKDEATSCSLHRSAHNATH 76
Query: 114 G---CQLQKKEIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQL 170
C + F V + D Q L + P P N+T+ Q
Sbjct: 77 ATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVTV--TFSGQY 134
Query: 171 ELNWNNRF-------LNHCLEHLVQYRTDWDHSWTEQ------SVDYRHKFSLPSVDGQK 217
++W + + L L++ +QYR D W SVD R LP ++ +K
Sbjct: 135 NISWRSDYEDPAFYMLKGKLQYELQYRNRGD-PWAVSPRRKLISVDSRSVSLLP-LEFRK 192
Query: 218 RYTFRVRSRFNPLCGSAQH--WSEWSHPIHWGSNTS--KE--NPFLFALEAVVI 265
++ ++ R P+ GS+ WSEWS P+ + + + KE NP L L +VI
Sbjct: 193 DSSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVI 246
>gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
Length = 551
Score = 42.0 bits (97), Expect = 9e-04
Identities = 72/361 (19%), Positives = 129/361 (35%), Gaps = 55/361 (15%)
Query: 42 LTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQK 101
L + T S + + CF + ++C W+ Q T+ +H W D + +
Sbjct: 16 LLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAW---PDRRRWNQ 72
Query: 102 CSHYLFSEEITSGCQL-------QKKEIHLYQTFVVQLQDPREPRRQATQMLK-LQNLVI 153
L + + C L QK T V ++ R A Q K +NL +
Sbjct: 73 TCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRL 132
Query: 154 PWAPENLTLHKLSESQLELNWNNRFLNHCLEHLVQYRT---DWDHSWTEQSV----DYRH 206
AP +L + + + ++W +H E +++ H+W E + +
Sbjct: 133 -MAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQE 191
Query: 207 KFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVV-- 264
L ++ +Y F+VR + PL G WS WS P+ + + P + +
Sbjct: 192 WICLETLTPDTQYEFQVRVK--PLQGEFTTWSPWSQPLAF-----RTKPAALGKDTIPWL 244
Query: 265 --ISVGSMGLIISLLCVYF---------WLERTMP--RIPTLKNLEDLVTEYHGNFSAW- 310
+ VG G ++ VY WL++ + K L +E+ G+ W
Sbjct: 245 GHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWL 304
Query: 311 -------SGVSKGLAESLQP------DYSERLCLVSEIPPKGGALGEGPGASPCNQHSPY 357
S GLA + P D +L L + P+ +L + C + Y
Sbjct: 305 SSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGY 364
Query: 358 W 358
+
Sbjct: 365 F 365
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 41.2 bits (95), Expect = 0.001
Identities = 60/269 (22%), Positives = 101/269 (37%), Gaps = 34/269 (12%)
Query: 9 TSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPE----VQCFV 64
+S+ F + L + L ILT E + +S LP PE + C V
Sbjct: 87 SSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI---------ISGLP-PEKPKNLSCIV 136
Query: 65 FNVEYMNCTWNSSSEPQ-PTNLTLHY-WYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI 122
+ M C W+ E TN TL W + D K + + C + +
Sbjct: 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK-------RDTPTSCTVDYSTV 189
Query: 123 HLYQTFVVQLQDPREPRRQATQMLKLQNL--VIPWAPENLTLHKLSE--SQLELNWNNRF 178
+ + V ++ + + + + V P P NL++ E S L+L W N
Sbjct: 190 Y-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
Query: 179 LNHC--LEHLVQYRTDWDHSWT----EQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCG 232
+ L++ +QYRT +W+ E + R F++ + Y FR+R G
Sbjct: 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
Query: 233 SAQHWSEWSHPIHWGSNTSKENPFLFALE 261
WSE + I + SK F + ++
Sbjct: 309 YWSDWSEEASGITYEDRPSKAPSFWYKID 337
>gi|28559023 interleukin 5 receptor, alpha isoform 2 precursor [Homo
sapiens]
Length = 333
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 14/186 (7%)
Query: 70 MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124
++CTW ++ P+ T L+Y Y S ++ Q+ S I C + I
Sbjct: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
Query: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181
+ +V R Q+ L + P N+T ++ ++L + W + F H
Sbjct: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
Query: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241
C ++ V+ + + + S+ +D +Y +VR+ + +C A WSEWS
Sbjct: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
Query: 242 HPIHWG 247
PI+ G
Sbjct: 327 QPIYVG 332
>gi|28559025 interleukin 5 receptor, alpha isoform 3 precursor [Homo
sapiens]
Length = 335
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 14/186 (7%)
Query: 70 MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124
++CTW ++ P+ T L+Y Y S ++ Q+ S I C + I
Sbjct: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
Query: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181
+ +V R Q+ L + P N+T ++ ++L + W + F H
Sbjct: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
Query: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241
C ++ V+ + + + S+ +D +Y +VR+ + +C A WSEWS
Sbjct: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
Query: 242 HPIHWG 247
PI+ G
Sbjct: 327 QPIYVG 332
>gi|28559031 interleukin 5 receptor, alpha isoform 3 precursor [Homo
sapiens]
Length = 335
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 14/186 (7%)
Query: 70 MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124
++CTW ++ P+ T L+Y Y S ++ Q+ S I C + I
Sbjct: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
Query: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181
+ +V R Q+ L + P N+T ++ ++L + W + F H
Sbjct: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
Query: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241
C ++ V+ + + + S+ +D +Y +VR+ + +C A WSEWS
Sbjct: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
Query: 242 HPIHWG 247
PI+ G
Sbjct: 327 QPIYVG 332
>gi|28559029 interleukin 5 receptor, alpha isoform 2 precursor [Homo
sapiens]
Length = 333
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/186 (22%), Positives = 77/186 (41%), Gaps = 14/186 (7%)
Query: 70 MNCTWNSSSE-PQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI----HL 124
++CTW ++ P+ T L+Y Y S ++ Q+ S I C + I
Sbjct: 153 LHCTWLVGTDAPEDTQYFLYYRY-GSWTEECQEYSKDTLGRNIA--CWFPRTFILSKGRD 209
Query: 125 YQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN---NRFLNH 181
+ +V R Q+ L + P N+T ++ ++L + W + F H
Sbjct: 210 WLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTA-EIEGTRLSIQWEKPVSAFPIH 268
Query: 182 CLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWS 241
C ++ V+ + + + S+ +D +Y +VR+ + +C A WSEWS
Sbjct: 269 CFDYEVKIHNTRNGYLQIEKLMTNAFISI--IDDLSKYDVQVRAAVSSMCREAGLWSEWS 326
Query: 242 HPIHWG 247
PI+ G
Sbjct: 327 QPIYVG 332
>gi|27437040 colony stimulating factor 2 receptor alpha chain
isoform e precursor [Homo sapiens]
Length = 233
Score = 39.7 bits (91), Expect = 0.004
Identities = 25/97 (25%), Positives = 38/97 (39%), Gaps = 21/97 (21%)
Query: 22 GLNTTILTPN-GNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEP 80
G +L PN G E T A F CF++N + MNCTW +
Sbjct: 104 GFQQKLLYPNSGREGTAAQNF-------------------SCFIYNADLMNCTW-ARGPT 143
Query: 81 QPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQL 117
P ++ + +NS + +C +Y+ GC L
Sbjct: 144 APRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHL 180
>gi|28610149 interleukin 6 signal transducer isoform 2 precursor
[Homo sapiens]
Length = 329
Score = 39.3 bits (90), Expect = 0.006
Identities = 57/249 (22%), Positives = 95/249 (38%), Gaps = 37/249 (14%)
Query: 9 TSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPE----VQCFV 64
+S+ F + L + L ILT E + +S LP PE + C V
Sbjct: 87 SSVTFTDIASLNIQLTCNILTFGQLEQNVYGITI---------ISGLP-PEKPKNLSCIV 136
Query: 65 FNVEYMNCTWNSSSEPQ-PTNLTLHY-WYKNSDNDKVQKCSHYLFSEEITSGCQLQKKEI 122
+ M C W+ E TN TL W + D K + + C + +
Sbjct: 137 NEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAK-------RDTPTSCTVDYSTV 189
Query: 123 HLYQTFVVQLQDPREPRRQATQMLKLQNL--VIPWAPENLTLHKLSE--SQLELNWNNRF 178
+ + V ++ + + + + V P P NL++ E S L+L W N
Sbjct: 190 Y-FVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPS 248
Query: 179 LNHC--LEHLVQYRTDWDHSWT----EQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCG 232
+ L++ +QYRT +W+ E + R F++ + Y FR+R G
Sbjct: 249 IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKG 308
Query: 233 SAQHWSEWS 241
+WS+WS
Sbjct: 309 ---YWSDWS 314
>gi|4557669 interleukin 4 receptor alpha chain isoform a precursor
[Homo sapiens]
Length = 825
Score = 38.1 bits (87), Expect = 0.013
Identities = 46/201 (22%), Positives = 78/201 (38%), Gaps = 26/201 (12%)
Query: 152 VIPWAPENLTLHKLSESQLELNWNNRFL--NHCLEHLVQYRTDWDHSWTEQSVDYRHKFS 209
V P AP NLT+H L L W+N + N+ HL W + Y +
Sbjct: 121 VKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYL 180
Query: 210 LPSV-----DGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVV 264
PS+ + ++R R R C + WSEWS W + S PF + ++
Sbjct: 181 EPSLRIAASTLKSGISYRARVRAWAQCYNTT-WSEWSPSTKW--HNSYREPF---EQHLL 234
Query: 265 ISVGSMGLIISLLCVYFWLERT---------MPRIPTLKNLEDLVTEYHGNFSAWSGVSK 315
+ V ++I +C+ ++ T +P + + ++ + G S W S+
Sbjct: 235 LGVSVSCIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQG--SQWEKRSR 292
Query: 316 GLAESLQPDYSERLCLVSEIP 336
G + P + CL +P
Sbjct: 293 GQEPAKCPHWKN--CLTKLLP 311
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 36.2 bits (82), Expect = 0.048
Identities = 34/162 (20%), Positives = 65/162 (40%), Gaps = 13/162 (8%)
Query: 73 TWNSSSEPQPTNLTLHYWYK--NSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVV 130
TW + + +T YW + + D DK +C+ + L K+ + ++
Sbjct: 13902 TWCEPDDDGGSPIT-GYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAE 13960
Query: 131 QLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNN-------RFLNHCL 183
L P +P + +L + PW P T+ + ++ + LNW + ++ +
Sbjct: 13961 NLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVI 14020
Query: 184 EHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRS 225
E L +W E +H LP + + Y+FRVR+
Sbjct: 14021 EMLKTGTDEWVRV-AEGVPTTQH--LLPGLMEGQEYSFRVRA 14059
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 36.2 bits (82), Expect = 0.048
Identities = 34/162 (20%), Positives = 65/162 (40%), Gaps = 13/162 (8%)
Query: 73 TWNSSSEPQPTNLTLHYWYK--NSDNDKVQKCSHYLFSEEITSGCQLQKKEIHLYQTFVV 130
TW + + +T YW + + D DK +C+ + L K+ + ++
Sbjct: 7597 TWCEPDDDGGSPIT-GYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAE 7655
Query: 131 QLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNN-------RFLNHCL 183
L P +P + +L + PW P T+ + ++ + LNW + ++ +
Sbjct: 7656 NLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVI 7715
Query: 184 EHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRS 225
E L +W E +H LP + + Y+FRVR+
Sbjct: 7716 EMLKTGTDEWVRV-AEGVPTTQH--LLPGLMEGQEYSFRVRA 7754
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,249,261
Number of Sequences: 37866
Number of extensions: 760448
Number of successful extensions: 2165
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 2082
Number of HSP's gapped (non-prelim): 85
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.