Search of human proteins with 4557819

Search of human proteins with 4557819

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557819 phenylalanine hydroxylase [Homo sapiens]
         (452 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557819 phenylalanine hydroxylase [Homo sapiens]                   922   0.0  
gi|31795563 tryptophan hydroxylase 2 [Homo sapiens]                   503   e-142
gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]                    492   e-139
gi|88900505 tyrosine hydroxylase isoform c [Homo sapiens]             452   e-127
gi|88900501 tyrosine hydroxylase isoform a [Homo sapiens]             452   e-127
gi|88900503 tyrosine hydroxylase isoform b [Homo sapiens]             452   e-127
gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]           32   0.90 
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...    32   1.5  
gi|4758648 kinesin family member 5B [Homo sapiens]                     32   1.5  
gi|56549113 debranching enzyme homolog 1 [Homo sapiens]                31   2.6  
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                       30   5.9  
gi|94421471 ring finger protein 17 [Homo sapiens]                      30   5.9  
gi|27894376 cell adhesion molecule with homology to L1CAM precur...    29   10.0 
gi|40255071 kelch-like 23 [Homo sapiens]                               29   10.0 

>gi|4557819 phenylalanine hydroxylase [Homo sapiens]
          Length = 452

 Score =  922 bits (2382), Expect = 0.0
 Identities = 452/452 (100%), Positives = 452/452 (100%)

Query: 1   MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDV 60
           MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDV
Sbjct: 1   MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDV 60

Query: 61  NLTHIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPW 120
           NLTHIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPW
Sbjct: 61  NLTHIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPW 120

Query: 121 FPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYM 180
           FPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYM
Sbjct: 121 FPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYM 180

Query: 181 EEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGF 240
           EEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGF
Sbjct: 181 EEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGF 240

Query: 241 RLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFA 300
           RLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFA
Sbjct: 241 RLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFA 300

Query: 301 QFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSE 360
           QFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSE
Sbjct: 301 QFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSE 360

Query: 361 KPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQR 420
           KPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQR
Sbjct: 361 KPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQR 420

Query: 421 IEVLDNTQQLKILADSINSEIGILCSALQKIK 452
           IEVLDNTQQLKILADSINSEIGILCSALQKIK
Sbjct: 421 IEVLDNTQQLKILADSINSEIGILCSALQKIK 452


>gi|31795563 tryptophan hydroxylase 2 [Homo sapiens]
          Length = 490

 Score =  503 bits (1296), Expect = e-142
 Identities = 247/455 (54%), Positives = 321/455 (70%), Gaps = 5/455 (1%)

Query: 1   MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDV 60
           + ++ L  P  G+   D G + S   +   ++G  +++FSLK EVG L K LRLF+E  V
Sbjct: 31  LGSSTLNKPNSGKN-DDKGNKGSSKREAATESGKTAVVFSLKNEVGGLVKALRLFQEKRV 89

Query: 61  NLTHIESRPSRLKKDEYEFFTHLD--KRSLPALTNIIKILRHDIGATVHE--LSRDKKKD 116
           N+ HIESR SR +  E E F   +  K     L  ++K     +     E   + +++ +
Sbjct: 90  NMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQTTIVTLNPPENIWTEEEELE 149

Query: 117 TVPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPR 176
            VPWFPR I ELD+ ++++L YG+ELDADHPGFKD VYR RRK F D+A  Y++GQPIPR
Sbjct: 150 DVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKYFVDVAMGYKYGQPIPR 209

Query: 177 VEYMEEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQT 236
           VEY EEE KTWG VF+ L  LY THAC EY   FPLL KYCG+ EDN+PQLEDVS FL+ 
Sbjct: 210 VEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYREDNVPQLEDVSMFLKE 269

Query: 237 CTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSD 296
            +GF +RPVAG LS RDFL GLA+RVFHCTQYIRHGS P+YTPEPD CHELLGHVPL +D
Sbjct: 270 RSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPEPDTCHELLGHVPLLAD 329

Query: 297 RSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQY 356
             FAQFSQEIGLASLGA DE ++KLAT Y+FT+EFGLCKQ   ++AYGAGLLSS GEL++
Sbjct: 330 PKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQLRAYGAGLLSSIGELKH 389

Query: 357 CLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDP 416
            LS+K  +   + + T +Q   +T FQ  Y+V+ESF +AKEK+R+FA +I RPFSV ++P
Sbjct: 390 ALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMRDFAKSITRPFSVYFNP 449

Query: 417 YTQRIEVLDNTQQLKILADSINSEIGILCSALQKI 451
           YTQ IE+L +T+ ++ +   + S++  +C AL K+
Sbjct: 450 YTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 484


>gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]
          Length = 444

 Score =  492 bits (1266), Expect = e-139
 Identities = 239/430 (55%), Positives = 308/430 (71%), Gaps = 4/430 (0%)

Query: 26  EDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFFTHLD- 84
           +D+  + G  SLIFSLK EVG L K L++F+E  VNL HIESR S+ +  E+E F   D 
Sbjct: 9   KDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDI 68

Query: 85  -KRSLPALTNIIKILRHDIGATVHE--LSRDKKKDTVPWFPRTIQELDRFANQILSYGAE 141
            +  L  + +++K   + +   + +    ++   +TVPWFP+ I +LD  AN++L YG+E
Sbjct: 69  NREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSE 128

Query: 142 LDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTH 201
           LDADHPGFKD VYR RRK FAD+A NY+HG PIP+VE+ EEE KTWGTVF+ L  LY TH
Sbjct: 129 LDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTH 188

Query: 202 ACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFR 261
           AC EY    PLL KYCG+ EDNIPQLEDVS FL+  TGF +RPVAG LS RDFL GLAFR
Sbjct: 189 ACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFR 248

Query: 262 VFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKL 321
           VFHCTQY+RH S P YTPEPD CHELLGHVPL ++ SFAQFSQEIGLASLGA +E ++KL
Sbjct: 249 VFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKL 308

Query: 322 ATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTE 381
           AT Y+FTVEFGLCKQ   ++ +GAGLLSS  EL++ LS   K+ P + + T  Q   +T 
Sbjct: 309 ATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITT 368

Query: 382 FQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEI 441
           FQ +Y+V+ESF DAKEK+R F  TI RPF V+Y+PYT+ I++L +T+ +    + +  ++
Sbjct: 369 FQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDL 428

Query: 442 GILCSALQKI 451
            ++  AL K+
Sbjct: 429 DVVSDALAKV 438


>gi|88900505 tyrosine hydroxylase isoform c [Homo sapiens]
          Length = 524

 Score =  452 bits (1163), Expect = e-127
 Identities = 224/423 (52%), Positives = 300/423 (70%), Gaps = 14/423 (3%)

Query: 35  ISLIFSLKE-EVGALAKVLRLFEENDVNLTHIESRPSRLKK---DEYEFFTHLDKR--SL 88
           ++L+FS +  +  AL++ +++FE  +  + H+E+RP++  +      E+F  L+ R   L
Sbjct: 109 LNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDL 168

Query: 89  PALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDRFANQILSYGAELDADHPG 148
            AL + ++ +  D+        R      VPWFPR + ELD+  + +  +  +LD DHPG
Sbjct: 169 AALLSGVRQVSEDV--------RSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPG 220

Query: 149 FKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNH 208
           F D VYR RRK  A+IA+ YRHG PIPRVEY  EE  TW  V+ TLK LY THAC E+  
Sbjct: 221 FSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLE 280

Query: 209 IFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQY 268
            F LLE++ G+ EDNIPQLEDVS+FL+  TGF+LRPVAGLLS+RDFL  LAFRVF CTQY
Sbjct: 281 AFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQY 340

Query: 269 IRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFT 328
           IRH S PM++PEPD CHELLGHVP+ +DR+FAQFSQ+IGLASLGA DE IEKL+T+YWFT
Sbjct: 341 IRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFT 400

Query: 329 VEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYV 388
           VEFGLCKQ   +KAYGAGLLSS+GEL +CLSE+P++   + E  A+Q Y    +Q +Y+V
Sbjct: 401 VEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFV 460

Query: 389 AESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSAL 448
           +ESF+DAK+K+R++A+ I RPFSV++DPYT  I+VLD+ Q ++   + +  E+  L  AL
Sbjct: 461 SESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHAL 520

Query: 449 QKI 451
             I
Sbjct: 521 SAI 523


>gi|88900501 tyrosine hydroxylase isoform a [Homo sapiens]
          Length = 528

 Score =  452 bits (1163), Expect = e-127
 Identities = 224/423 (52%), Positives = 300/423 (70%), Gaps = 14/423 (3%)

Query: 35  ISLIFSLKE-EVGALAKVLRLFEENDVNLTHIESRPSRLKK---DEYEFFTHLDKR--SL 88
           ++L+FS +  +  AL++ +++FE  +  + H+E+RP++  +      E+F  L+ R   L
Sbjct: 113 LNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDL 172

Query: 89  PALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDRFANQILSYGAELDADHPG 148
            AL + ++ +  D+        R      VPWFPR + ELD+  + +  +  +LD DHPG
Sbjct: 173 AALLSGVRQVSEDV--------RSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPG 224

Query: 149 FKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNH 208
           F D VYR RRK  A+IA+ YRHG PIPRVEY  EE  TW  V+ TLK LY THAC E+  
Sbjct: 225 FSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLE 284

Query: 209 IFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQY 268
            F LLE++ G+ EDNIPQLEDVS+FL+  TGF+LRPVAGLLS+RDFL  LAFRVF CTQY
Sbjct: 285 AFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQY 344

Query: 269 IRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFT 328
           IRH S PM++PEPD CHELLGHVP+ +DR+FAQFSQ+IGLASLGA DE IEKL+T+YWFT
Sbjct: 345 IRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFT 404

Query: 329 VEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYV 388
           VEFGLCKQ   +KAYGAGLLSS+GEL +CLSE+P++   + E  A+Q Y    +Q +Y+V
Sbjct: 405 VEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFV 464

Query: 389 AESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSAL 448
           +ESF+DAK+K+R++A+ I RPFSV++DPYT  I+VLD+ Q ++   + +  E+  L  AL
Sbjct: 465 SESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHAL 524

Query: 449 QKI 451
             I
Sbjct: 525 SAI 527


>gi|88900503 tyrosine hydroxylase isoform b [Homo sapiens]
          Length = 497

 Score =  452 bits (1163), Expect = e-127
 Identities = 224/423 (52%), Positives = 300/423 (70%), Gaps = 14/423 (3%)

Query: 35  ISLIFSLKE-EVGALAKVLRLFEENDVNLTHIESRPSRLKK---DEYEFFTHLDKR--SL 88
           ++L+FS +  +  AL++ +++FE  +  + H+E+RP++  +      E+F  L+ R   L
Sbjct: 82  LNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDL 141

Query: 89  PALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDRFANQILSYGAELDADHPG 148
            AL + ++ +  D+        R      VPWFPR + ELD+  + +  +  +LD DHPG
Sbjct: 142 AALLSGVRQVSEDV--------RSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPG 193

Query: 149 FKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNH 208
           F D VYR RRK  A+IA+ YRHG PIPRVEY  EE  TW  V+ TLK LY THAC E+  
Sbjct: 194 FSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLE 253

Query: 209 IFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQY 268
            F LLE++ G+ EDNIPQLEDVS+FL+  TGF+LRPVAGLLS+RDFL  LAFRVF CTQY
Sbjct: 254 AFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQY 313

Query: 269 IRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFT 328
           IRH S PM++PEPD CHELLGHVP+ +DR+FAQFSQ+IGLASLGA DE IEKL+T+YWFT
Sbjct: 314 IRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFT 373

Query: 329 VEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYV 388
           VEFGLCKQ   +KAYGAGLLSS+GEL +CLSE+P++   + E  A+Q Y    +Q +Y+V
Sbjct: 374 VEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFV 433

Query: 389 AESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSAL 448
           +ESF+DAK+K+R++A+ I RPFSV++DPYT  I+VLD+ Q ++   + +  E+  L  AL
Sbjct: 434 SESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHAL 493

Query: 449 QKI 451
             I
Sbjct: 494 SAI 496


>gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]
          Length = 154

 Score = 32.3 bits (72), Expect = 0.90
 Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 10/120 (8%)

Query: 11  LGRKLSDFGQETSYIEDNC----NQNGAISL-IFSLK---EEVGALAKVLRLFEENDVNL 62
           L +K  D   E   +   C      N  I   + S+K   +E   L +  ++ EE  +NL
Sbjct: 34  LKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILNL 93

Query: 63  -THIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPWF 121
            TH+E+    L K + E+ +  D+R++ A+  + +I        V ++ R+ K+ T+P F
Sbjct: 94  KTHMENNMVELSKLQ-EYKSEPDERAIQAVEKLEEIHLQMEADCVEQIIRETKRSTLPKF 152


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 15/94 (15%)

Query: 143  DADHPGFKDPVYRARRKQFAD--------IAYNYRHGQPIPRVEYMEEEKKTWGTVFKTL 194
            +A+ PG K P  R   +  A         +A++  +G  IP+ E+  +EK    T FK  
Sbjct: 1556 EANRPG-KVPFLRVATESSAKTPSKLLDPLAWDNHYGTQIPKEEWKSQEKSPEKTAFKKK 1614

Query: 195  KSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLE 228
             ++   +AC E NH    + +       N P++E
Sbjct: 1615 DTILSLNAC-ESNHAIAAINE-----GQNKPEIE 1642


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 31.6 bits (70), Expect = 1.5
 Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 7/64 (10%)

Query: 393 NDA-KEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCS---AL 448
           NDA KE+V+     +    +V YD  +Q +E  D T++ ++L+D +N +   L S    L
Sbjct: 481 NDASKEEVKEVLQALEE-LAVNYDQKSQEVE--DKTKEYELLSDELNQKSATLASIDAEL 537

Query: 449 QKIK 452
           QK+K
Sbjct: 538 QKLK 541


>gi|56549113 debranching enzyme homolog 1 [Homo sapiens]
          Length = 544

 Score = 30.8 bits (68), Expect = 2.6
 Identities = 26/84 (30%), Positives = 37/84 (44%), Gaps = 8/84 (9%)

Query: 293 LFSDRSFAQFSQEIGLASLGAP--DEYIEKLATIYWFT----VEFGLCKQGDSIKAYGAG 346
           L   +SF  F QE+   +LG+P   E +E L   YWF+    V+F    Q  +       
Sbjct: 189 LLKTKSF--FRQEVENNTLGSPAASELLEHLKPTYWFSAHLHVKFAALMQHQAKDKGQTA 246

Query: 347 LLSSFGELQYCLSEKPKLLPLELE 370
             + F  L  CL  +  L  LE+E
Sbjct: 247 RATKFLALDKCLPHRDFLQILEIE 270


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 12/97 (12%)

Query: 32  NGAISLIFSLKEEVGALAK-VLRLFEENDVNLTHIESRPSRLKKDEYEFFT--------- 81
           +G +S I    +E G++    +   +   V    +E +    K++    F+         
Sbjct: 80  HGCVSKILCRYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLK 139

Query: 82  --HLDKRSLPALTNIIKILRHDIGATVHELSRDKKKD 116
             H D+ ++P++++I ++LR   G    E   DKK+D
Sbjct: 140 DGHCDRSTVPSVSSISRVLRIKFGKKEEEDEADKKED 176


>gi|94421471 ring finger protein 17 [Homo sapiens]
          Length = 1623

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 356  YCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVR-Y 414
            + LSEK   +PLE E + + N   T F P    A+  ++  +KV  F   I  P + R Y
Sbjct: 1115 HSLSEKSLEVPLEQEDSVVTNCIKTNFDPDKKTADIISE--QKVSEFQEKILEPRTTRGY 1172

Query: 415  DP 416
             P
Sbjct: 1173 KP 1174


>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
           [Homo sapiens]
          Length = 1224

 Score = 28.9 bits (63), Expect = 10.0
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 3/59 (5%)

Query: 354 LQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSV 412
           L+Y ++ KP+  P+E E+  + N+T+    P  Y      D K +  N   + P P SV
Sbjct: 761 LEYRVTWKPQGAPVEWEEETVTNHTLRVMTPAVYAP---YDVKVQAINQLGSGPDPQSV 816


>gi|40255071 kelch-like 23 [Homo sapiens]
          Length = 558

 Score = 28.9 bits (63), Expect = 10.0
 Identities = 13/52 (25%), Positives = 26/52 (50%), Gaps = 1/52 (1%)

Query: 168 YRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGF 219
           YR G P    E+ +  K+ W  +   +K +    AC  ++ I+ ++  +CG+
Sbjct: 377 YRKGAPAEEAEFYDPLKEKWIPIANMIKGVGNATACVLHDVIY-VIGGHCGY 427


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,330,242
Number of Sequences: 37866
Number of extensions: 784908
Number of successful extensions: 1578
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1564
Number of HSP's gapped (non-prelim): 15
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.