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Search of human proteins with 4557535
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
(764 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 1498 0.0
gi|4505697 pendrin [Homo sapiens] 683 0.0
gi|39752683 prestin isoform a [Homo sapiens] 513 e-145
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 503 e-142
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 499 e-141
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 499 e-141
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 494 e-139
gi|45827800 prestin isoform b [Homo sapiens] 493 e-139
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 439 e-123
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 439 e-123
gi|45827802 prestin isoform c [Homo sapiens] 429 e-120
gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 399 e-111
gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 347 2e-95
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 347 2e-95
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 328 1e-89
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 326 4e-89
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 314 2e-85
gi|45827804 prestin isoform d [Homo sapiens] 269 6e-72
gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 260 4e-69
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 206 7e-53
gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 173 6e-43
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 158 2e-38
gi|20336274 solute carrier family 26, member 1 isoform b [Homo s... 107 4e-23
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 32 1.7
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 32 1.7
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 32 1.7
gi|148806891 hypothetical protein LOC54906 [Homo sapiens] 32 2.9
gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit... 31 4.9
gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit ... 31 4.9
gi|239748761 PREDICTED: hypothetical protein XP_002346789 [Homo ... 30 6.4
>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
Length = 764
Score = 1498 bits (3879), Expect = 0.0
Identities = 764/764 (100%), Positives = 764/764 (100%)
Query: 1 MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPI 60
MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPI
Sbjct: 1 MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPI 60
Query: 61 ASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFG 120
ASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFG
Sbjct: 61 ASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFG 120
Query: 121 TSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAA 180
TSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAA
Sbjct: 121 TSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAA 180
Query: 181 SVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDP 240
SVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDP
Sbjct: 181 SVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDP 240
Query: 241 VSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIA 300
VSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIA
Sbjct: 241 VSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIA 300
Query: 301 AGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASV 360
AGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASV
Sbjct: 301 AGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASV 360
Query: 361 YSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAII 420
YSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAII
Sbjct: 361 YSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAII 420
Query: 421 VLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTI 480
VLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTI
Sbjct: 421 VLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTI 480
Query: 481 VLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRC 540
VLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRC
Sbjct: 481 VLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRC 540
Query: 541 PSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDT 600
PSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDT
Sbjct: 541 PSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDT 600
Query: 601 IKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLD 660
IKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLD
Sbjct: 601 IKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLD 660
Query: 661 VSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHI 720
VSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHI
Sbjct: 661 VSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHI 720
Query: 721 LMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF 764
LMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF
Sbjct: 721 LMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF 764
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 683 bits (1763), Expect = 0.0
Identities = 347/716 (48%), Positives = 478/716 (66%), Gaps = 10/716 (1%)
Query: 9 YIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYR 68
Y+V+RPVYS AF++ H++ + KT + L CCSCS ++A ++ +L PI WLP YR
Sbjct: 20 YMVSRPVYSELAFQQQHERRLQERKTLRESLAKCCSCSRKRAFGVLKTLVPILEWLPKYR 79
Query: 69 LKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVG 128
+KEWLLSD++SG+STG+VA LQG+A+ALL +P YGLY++FFP + Y FGTSRHISVG
Sbjct: 80 VKEWLLSDVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGTSRHISVG 139
Query: 129 PFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDD---ERVRVAAAASVTVL 185
PFP++S+MVG V PD + N++++D + RV A+++T+L
Sbjct: 140 PFPVVSLMVG----SVVLSMAPDEHFLVSSSNGTVLNTTMIDTAARDTARVLIASALTLL 195
Query: 186 SGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFK 245
GIIQL FG L+IGF+V YL++ L+ GFTTAAA VLVSQLK + ++ ++ +SI
Sbjct: 196 VGIIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIY 255
Query: 246 VLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSY 305
L +F I TN+AD L+ ++V VKE+N RF+ K+PVPIPIE I+T+IA +SY
Sbjct: 256 TLVEIFQNIGDTNLADFTAGLLTIVVCMAVKELNDRFRHKIPVPIPIEVIVTIIATAISY 315
Query: 306 GCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKY 365
G + + + +V + GF PP P V F + F IA+VA+A+A SV VY+ KY
Sbjct: 316 GANLEKNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFSIAVVAYAIAVSVGKVYATKY 375
Query: 366 DYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVV 425
DY +DGNQE IA G+ NI G F F +TALSR+AVQESTGGKTQ+AG+I A IV+I +
Sbjct: 376 DYTIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAI 435
Query: 426 LAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLG 485
LA+G LL PLQKSVLAA+ + NLKGM MQ +I RLWR++K D +IW+ T I +I+LGL
Sbjct: 436 LALGKLLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQNKIDAVIWVFTCIVSIILGLD 495
Query: 486 LGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIY 545
LGL A + F LLT+V R QFP + L +I T+IYK+ K+Y ++ EP+GVKI R SPI+
Sbjct: 496 LGLLAGLIFGLLTVVLRVQFPSWNGLGSIPSTDIYKSTKNYKNIEEPQGVKILRFSSPIF 555
Query: 546 FANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFIC-TVDTIKDS 604
+ N+ F++ + VGF +R+ KR KALRKI+KL K G L+ T G I V T
Sbjct: 556 YGNVDGFKKCIKSTVGFDAIRVYNKRLKALRKIQKLIKSGQLRATKNGIISDAVSTNNAF 615
Query: 605 DEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSV 664
+ + D +E LD P T ++ +DWN +LP+ + VPK+ +HSL+LD A+SFLDV V
Sbjct: 616 EPDEDIEDLEELDIP--TKEIEIQVDWNSELPVKVNVPKVPIHSLVLDCGAISFLDVVGV 673
Query: 665 RGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHI 720
R L+ I++EF RI V+VY D IEKL + FFD ++ FFLT+HDA+L++
Sbjct: 674 RSLRVIVKEFQRIDVNVYFASLQDYVIEKLEQCGFFDDNIRKDTFFLTVHDAILYL 729
>gi|39752683 prestin isoform a [Homo sapiens]
Length = 744
Score = 513 bits (1322), Expect = e-145
Identities = 288/735 (39%), Positives = 432/735 (58%), Gaps = 24/735 (3%)
Query: 8 QYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAY 67
+Y V RP++S +E + + D LK +C+P+K + I+ PI WLPAY
Sbjct: 15 RYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAY 74
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+ KE++L D+VSGISTG++ + QGLAFA+L +PP++GLY+SF+P I+Y F GTSRHIS+
Sbjct: 75 KFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISI 134
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
GPF ++S+M+G G + VPD G+ N +N + D RV+VA SVT+LSG
Sbjct: 135 GPFAVISLMIG----GVAVRLVPDDIVIPGGV-NATNGTEARDALRVKVAM--SVTLLSG 187
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
IIQ G+ R GFV IYL+E L+ GFTTAAAVHV S LK++F + ++ IF V+
Sbjct: 188 IIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYS---GIFSVV 244
Query: 248 YS---VFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVS 304
YS V ++ N+ L L+V ++ KE N+RFK+KLP PIP+EF V+ G+S
Sbjct: 245 YSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGIS 304
Query: 305 YGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLK 364
G + K + V VVG + G PP PD F D IA+V F+V S+A + K
Sbjct: 305 AGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANK 364
Query: 365 YDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIV 424
+ Y +DGNQELIALGL N + +F+ F+ S +LSRS VQE TGGKTQ+AG + ++++L+V
Sbjct: 365 HGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLV 424
Query: 425 VLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGL 484
+LA GFL L ++VL+A+ + NLKGM MQF+++ WR K + IW+ TF+ ++ LGL
Sbjct: 425 ILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGL 484
Query: 485 GLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPI 544
GL +V LLT+++RTQ P L + T++Y + Y ++ E G+KIF+ +PI
Sbjct: 485 DYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPI 544
Query: 545 YFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRK-LQKQGLLQVTPKGFICTVDTIKD 603
Y+AN + L G +P I+ R KA+RK K + + T VD
Sbjct: 545 YYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDA 604
Query: 604 SDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSS 663
+ E ++ +++ I +T F + +P P ++H++ILDF+ V+F+D
Sbjct: 605 TKPEEEDGEVKYPPIVIKST---FPEEMQRFMP-----PGDNVHTVILDFTQVNFIDSVG 656
Query: 664 VRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMK 723
V+ L I++E+ + + VY+ G + L R FF+ + F +IHDAVL ++
Sbjct: 657 VKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLR 716
Query: 724 KDYSTSKFN--PSQE 736
+ + + + PSQE
Sbjct: 717 EALAEQEASAPPSQE 731
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 503 bits (1295), Expect = e-142
Identities = 277/731 (37%), Positives = 434/731 (59%), Gaps = 35/731 (4%)
Query: 9 YIVARPVYSTNAFEENHKKTGRHHKTFLDHL-KVCCSCSPQKAKRIVLSLFPIASWLPAY 67
Y + RP+ + EE GR H + CS +A ++L P+ WLP Y
Sbjct: 29 YHMERPLLNQEHLEE----LGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRY 84
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+++WLL D++SG+S I+ + QGLA+ALL +PPV+GLY+SF+P IY FGTSRHISV
Sbjct: 85 PVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISV 144
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
G F ++S+MVG +A+ D + N + D RV+VA+ SV V G
Sbjct: 145 GTFAVMSVMVGSVTESLAPQALND----------SMINETARDAARVQVASTLSVLV--G 192
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
+ Q+ G++ GFVV YLSE L+ G+TTAAAV V VSQLK++F L + SH+ P+S+ +
Sbjct: 193 LFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTV 252
Query: 248 YSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGC 307
V ++ ++ + +VTA + +V+ +VK +N + + +LP+PIP E + + A G+SYG
Sbjct: 253 LEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGM 312
Query: 308 DFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDY 367
K+RF+V VVG++ G PP+ P+ + F VG F IA+V FA+A S+ +++L++ Y
Sbjct: 313 GLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGY 372
Query: 368 PLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLA 427
+D NQEL+ALGL N++ G+F+ F S ++SRS VQESTGG +Q+AG I ++ +L++++
Sbjct: 373 RVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVK 432
Query: 428 IGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLG 487
+G L L K+VLAA+ + NLKGML Q +++ LW+ ++ D LIW++TF TI+L L LG
Sbjct: 433 LGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLG 492
Query: 488 LAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFA 547
L +V F LL +V RTQ P S L + T+IY++ +Y + E GVK+FR + +YFA
Sbjct: 493 LVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFA 552
Query: 548 NIGFFRRKLIDAVGFSPLRILRKRNKALR-----KIRKLQKQGLLQ---VTPKGFICTVD 599
N F+ L G ++ ++ K L+ K+++LQK+ L+ +PKG +++
Sbjct: 553 NAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSIN 612
Query: 600 TIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN--------DDLPLN-IEVPKISLHSLI 650
+ S E++ +N +E +++ D N D L + +P+ HSLI
Sbjct: 613 -VNTSLEDMRSNNVEDCKMMVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLI 671
Query: 651 LDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFF 710
LD A+SF+D ++ LK+I +F I+V+VY+ + +L FFD + F
Sbjct: 672 LDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLF 731
Query: 711 LTIHDAVLHIL 721
++HDAV L
Sbjct: 732 ASVHDAVTFAL 742
>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
sapiens]
Length = 738
Score = 499 bits (1286), Expect = e-141
Identities = 275/731 (37%), Positives = 430/731 (58%), Gaps = 34/731 (4%)
Query: 9 YIVARPVYSTNAFEENHKKTGRHHKTFLDHL-KVCCSCSPQKAKRIVLSLFPIASWLPAY 67
Y + RP+ + EE GR H + CS +A ++L P+ WLP Y
Sbjct: 8 YHMERPLLNQEHLEE----LGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRY 63
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+++WLL D++SG+S I+ + QGLA+ALL +PPV+GLY+SF+P IY FGTSRHISV
Sbjct: 64 PVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISV 123
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
G F ++S+MVG +A+ D + N + D RV+VA+ SV V G
Sbjct: 124 GTFAVMSVMVGSVTESLAPQALND----------SMINETARDAARVQVASTLSVLV--G 171
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
+ Q+ G++ GFVV YLSE L+ G+TTAAAV V VSQLK++F L + SH+ P+S+ +
Sbjct: 172 LFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTV 231
Query: 248 YSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGC 307
V ++ ++ + +VTA + +V+ +VK +N + + +LP+PIP E + + A G+SYG
Sbjct: 232 LEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGM 291
Query: 308 DFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDY 367
K+RF+V VVG++ G PP+ P+ + F VG F IA+V FA+A S+ +++L++ Y
Sbjct: 292 GLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGY 351
Query: 368 PLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLA 427
+D NQEL+ALGL N++ G+F+ F S ++SRS VQESTGG +Q+AG I ++ +L++++
Sbjct: 352 RVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVK 411
Query: 428 IGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLG 487
+G L L K+VLAA+ + NLKGML Q +++ LW+ ++ D LIW++TF TI+L L LG
Sbjct: 412 LGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLG 471
Query: 488 LAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFA 547
L +V F LL +V RTQ P S L + T+IY++ +Y + E GVK+FR + +YFA
Sbjct: 472 LVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFA 531
Query: 548 NIGFFRRKLIDAVGFSPLRILRKRNKALR-----KIRKLQKQGLLQ---VTPKGFICTVD 599
N F+ L G ++ ++ K L+ K+++LQK+ L+ +PKG +++
Sbjct: 532 NAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSIN 591
Query: 600 TIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN--------DDLPLN-IEVPKISLHSLI 650
++ NN + +++ D N D L + +P+ HSLI
Sbjct: 592 VNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLI 651
Query: 651 LDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFF 710
LD A+SF+D ++ LK+I +F I+V+VY+ + +L FFD + F
Sbjct: 652 LDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLF 711
Query: 711 LTIHDAVLHIL 721
++HDAV L
Sbjct: 712 ASVHDAVTFAL 722
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 499 bits (1286), Expect = e-141
Identities = 275/731 (37%), Positives = 430/731 (58%), Gaps = 34/731 (4%)
Query: 9 YIVARPVYSTNAFEENHKKTGRHHKTFLDHL-KVCCSCSPQKAKRIVLSLFPIASWLPAY 67
Y + RP+ + EE GR H + CS +A ++L P+ WLP Y
Sbjct: 29 YHMERPLLNQEHLEE----LGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRY 84
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+++WLL D++SG+S I+ + QGLA+ALL +PPV+GLY+SF+P IY FGTSRHISV
Sbjct: 85 PVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISV 144
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
G F ++S+MVG +A+ D + N + D RV+VA+ SV V G
Sbjct: 145 GTFAVMSVMVGSVTESLAPQALND----------SMINETARDAARVQVASTLSVLV--G 192
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
+ Q+ G++ GFVV YLSE L+ G+TTAAAV V VSQLK++F L + SH+ P+S+ +
Sbjct: 193 LFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTV 252
Query: 248 YSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGC 307
V ++ ++ + +VTA + +V+ +VK +N + + +LP+PIP E + + A G+SYG
Sbjct: 253 LEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGM 312
Query: 308 DFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDY 367
K+RF+V VVG++ G PP+ P+ + F VG F IA+V FA+A S+ +++L++ Y
Sbjct: 313 GLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGY 372
Query: 368 PLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLA 427
+D NQEL+ALGL N++ G+F+ F S ++SRS VQESTGG +Q+AG I ++ +L++++
Sbjct: 373 RVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVK 432
Query: 428 IGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLG 487
+G L L K+VLAA+ + NLKGML Q +++ LW+ ++ D LIW++TF TI+L L LG
Sbjct: 433 LGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLG 492
Query: 488 LAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFA 547
L +V F LL +V RTQ P S L + T+IY++ +Y + E GVK+FR + +YFA
Sbjct: 493 LVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFA 552
Query: 548 NIGFFRRKLIDAVGFSPLRILRKRNKALR-----KIRKLQKQGLLQ---VTPKGFICTVD 599
N F+ L G ++ ++ K L+ K+++LQK+ L+ +PKG +++
Sbjct: 553 NAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAASPKGASVSIN 612
Query: 600 TIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN--------DDLPLN-IEVPKISLHSLI 650
++ NN + +++ D N D L + +P+ HSLI
Sbjct: 613 VNTSLEDMRSNNVEDCKMMQVSSGDKMEDATANGQEDSKAPDGSTLKALGLPQPDFHSLI 672
Query: 651 LDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFF 710
LD A+SF+D ++ LK+I +F I+V+VY+ + +L FFD + F
Sbjct: 673 LDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLF 732
Query: 711 LTIHDAVLHIL 721
++HDAV L
Sbjct: 733 ASVHDAVTFAL 743
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 494 bits (1272), Expect = e-139
Identities = 274/724 (37%), Positives = 424/724 (58%), Gaps = 39/724 (5%)
Query: 9 YIVARPVYSTNAFEENHKKTGRHHKTFLDHL-KVCCSCSPQKAKRIVLSLFPIASWLPAY 67
Y + RP+ + EE GR H + CS +A ++L P+ WLP Y
Sbjct: 29 YHMERPLLNQEHLEE----LGRWGSAPRTHQWRTWLQCSRARAYALLLQHLPVLVWLPRY 84
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+++WLL D++SG+S I+ + QGLA+ALL +PPV+GLY+SF+P IY FGTSRHISV
Sbjct: 85 PVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPVFGLYSSFYPVFIYFLFGTSRHISV 144
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
G F ++S+MVG +A+ D + N + D RV+VA+ SV V G
Sbjct: 145 GTFAVMSVMVGSVTESLAPQALND----------SMINETARDAARVQVASTLSVLV--G 192
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
+ Q+ G++ GFVV YLSE L+ G+TTAAAV V VSQLK++F L + SH+ P+S+ +
Sbjct: 193 LFQVGLGLIHFGFVVTYLSEPLVRGYTTAAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTV 252
Query: 248 YSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGC 307
V ++ ++ + +VTA + +V+ +VK +N + + +LP+PIP E + + A G+SYG
Sbjct: 253 LEVCWKLPQSKVGTVVTAAVAGVVLVVVKLLNDKLQQQLPMPIPGELLTLIGATGISYGM 312
Query: 308 DFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDY 367
K+RF+V VVG++ G PP+ P+ + F VG F IA+V FA+A S+ +++L++ Y
Sbjct: 313 GLKHRFEVDVVGNIPAGLVPPVAPNTQLFSKLVGSAFTIAVVGFAIAISLGKIFALRHGY 372
Query: 368 PLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLA 427
+D NQEL+ALGL N++ G+F+ F S ++SRS VQESTGG +Q+AG I ++ +L++++
Sbjct: 373 RVDSNQELVALGLSNLIGGIFQCFPVSCSMSRSLVQESTGGNSQVAGAISSLFILLIIVK 432
Query: 428 IGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLG 487
+G L L K+VLAA+ + NLKGML Q +++ LW+ ++ D LIW++TF TI+L L LG
Sbjct: 433 LGELFHDLPKAVLAAIIIVNLKGMLRQLSDMRSLWKANRADLLIWLVTFTATILLNLDLG 492
Query: 488 LAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFA 547
L +V F LL +V RTQ P S L + T+IY++ +Y + E GVK+FR + +YFA
Sbjct: 493 LVVAVIFSLLLVVVRTQMPHYSVLGQVPDTDIYRDVAEYSEAKEVRGVKVFRSSATVYFA 552
Query: 548 NIGFFRRKLIDAVGFSPLRILRKRNKALR-----KIRKLQKQGLL--QVTPKGFICTVDT 600
N F+ L G ++ ++ K L+ K+++LQK+ L Q P C
Sbjct: 553 NAEFYSDALKQRCGVDVDFLISQKKKLLKKQEQLKLKQLQKEEKLRKQAGPLLSACLAPQ 612
Query: 601 IKDSDEELDN---NQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVS 657
S +++++ N E P +T + +P+ HSLILD A+S
Sbjct: 613 QVSSGDKMEDATANGQEDSKAPDGST------------LKALGLPQPDFHSLILDLGALS 660
Query: 658 FLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAV 717
F+D ++ LK+I +F I+V+VY+ + +L FFD + F ++HDAV
Sbjct: 661 FVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAV 720
Query: 718 LHIL 721
L
Sbjct: 721 TFAL 724
>gi|45827800 prestin isoform b [Homo sapiens]
Length = 685
Score = 493 bits (1269), Expect = e-139
Identities = 273/682 (40%), Positives = 407/682 (59%), Gaps = 22/682 (3%)
Query: 8 QYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAY 67
+Y V RP++S +E + + D LK +C+P+K + I+ PI WLPAY
Sbjct: 15 RYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAY 74
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+ KE++L D+VSGISTG++ + QGLAFA+L +PP++GLY+SF+P I+Y F GTSRHIS+
Sbjct: 75 KFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISI 134
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
GPF ++S+M+G G + VPD G+ N +N + D RV+VA SVT+LSG
Sbjct: 135 GPFAVISLMIG----GVAVRLVPDDIVIPGGV-NATNGTEARDALRVKVAM--SVTLLSG 187
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
IIQ G+ R GFV IYL+E L+ GFTTAAAVHV S LK++F + ++ IF V+
Sbjct: 188 IIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYS---GIFSVV 244
Query: 248 YS---VFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVS 304
YS V ++ N+ L L+V ++ KE N+RFK+KLP PIP+EF V+ G+S
Sbjct: 245 YSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGIS 304
Query: 305 YGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLK 364
G + K + V VVG + G PP PD F D IA+V F+V S+A + K
Sbjct: 305 AGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANK 364
Query: 365 YDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIV 424
+ Y +DGNQELIALGL N + +F+ F+ S +LSRS VQE TGGKTQ+AG + ++++L+V
Sbjct: 365 HGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLV 424
Query: 425 VLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGL 484
+LA GFL L ++VL+A+ + NLKGM MQF+++ WR K + IW+ TF+ ++ LGL
Sbjct: 425 ILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGL 484
Query: 485 GLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPI 544
GL +V LLT+++RTQ P L + T++Y + Y ++ E G+KIF+ +PI
Sbjct: 485 DYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPI 544
Query: 545 YFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRK-LQKQGLLQVTPKGFICTVDTIKD 603
Y+AN + L G +P I+ R KA+RK K + + T VD
Sbjct: 545 YYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDA 604
Query: 604 SDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSS 663
+ E ++ +++ I +T F + +P P ++H++ILDF+ V+F+D
Sbjct: 605 TKPEEEDGEVKYPPIVIKST---FPEEMQRFMP-----PGDNVHTVILDFTQVNFIDSVG 656
Query: 664 VRGLKSILQEFIRIKVDVYIVG 685
V+ L I++E+ + + VY+ G
Sbjct: 657 VKTLAGIVKEYGDVGIYVYLAG 678
>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
sapiens]
Length = 791
Score = 439 bits (1128), Expect = e-123
Identities = 254/737 (34%), Positives = 399/737 (54%), Gaps = 34/737 (4%)
Query: 8 QYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAY 67
+Y+V R YS F++ +K R + + L+ CS K K +V L P+ SWLP Y
Sbjct: 7 RYVVDRAAYSLTLFDDEFEKKDRTYPVG-EKLRNAFRCSSAKIKAVVFGLLPVLSWLPKY 65
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
++K++++ D++ G+S G + V QG+AFALL ++P V GLY+SFFP + Y F G +
Sbjct: 66 KIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVP 125
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDD---ERVRVAAAASVTV 184
G F ++S++VG + P+ NN+ N S +D E R+ +A++
Sbjct: 126 GTFAVISILVG----NICLQLAPESKFQVF---NNATNESYVDTAAMEAERLHVSATLAC 178
Query: 185 LSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIF 244
L+ IIQ+ G ++ GFV IYLSES I GF TAA + +L+S LK+IF LT+PS+T P SI
Sbjct: 179 LTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIV 238
Query: 245 KVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVS 304
+ + TNIA L+ ALI + +VKE+N R+ K+ PIP E I+ V+A +S
Sbjct: 239 FTFIDICKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAIS 298
Query: 305 YGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLK 364
GC ++ + +VG++ GF P++P V +++ +G F +A+V++ + ++ + K
Sbjct: 299 GGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANK 358
Query: 365 YDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIV 424
+ Y +D NQE+IALG N F+ ALS + + GGK+Q+A L +++V+I
Sbjct: 359 HGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMIT 418
Query: 425 VLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGL 484
+L +G L PL KSVL AL NLK L Q + LWRK K DC IW+++F+ + L L
Sbjct: 419 MLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSL 478
Query: 485 GLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPI 544
G+A VAF +L +VF+TQF LA + T+IY N K Y + +G+KI SP+
Sbjct: 479 PYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPL 538
Query: 545 YFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRK------LQKQGLLQVTPKGFICTV 598
YFAN FR+K+I G P ++L + K L+K K Q++ L T + +
Sbjct: 539 YFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQEL 598
Query: 599 DTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN----DDLPLNIEVPK----------- 643
++ D N + + + + F D + + P + E P
Sbjct: 599 QQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPP 658
Query: 644 -ISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFF-D 701
++ H+LILD S VSF+D+ ++ L + + +I V V++V ++ F D
Sbjct: 659 FVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFED 718
Query: 702 GEVKSSIFFLTIHDAVL 718
G ++ F +IHDAVL
Sbjct: 719 GSLECKHVFPSIHDAVL 735
>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
sapiens]
Length = 887
Score = 439 bits (1128), Expect = e-123
Identities = 254/737 (34%), Positives = 399/737 (54%), Gaps = 34/737 (4%)
Query: 8 QYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAY 67
+Y+V R YS F++ +K R + + L+ CS K K +V L P+ SWLP Y
Sbjct: 7 RYVVDRAAYSLTLFDDEFEKKDRTYPVG-EKLRNAFRCSSAKIKAVVFGLLPVLSWLPKY 65
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
++K++++ D++ G+S G + V QG+AFALL ++P V GLY+SFFP + Y F G +
Sbjct: 66 KIKDYIIPDLLGGLSGGSIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVP 125
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDD---ERVRVAAAASVTV 184
G F ++S++VG + P+ NN+ N S +D E R+ +A++
Sbjct: 126 GTFAVISILVG----NICLQLAPESKFQVF---NNATNESYVDTAAMEAERLHVSATLAC 178
Query: 185 LSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIF 244
L+ IIQ+ G ++ GFV IYLSES I GF TAA + +L+S LK+IF LT+PS+T P SI
Sbjct: 179 LTAIIQMGLGFMQFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIV 238
Query: 245 KVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVS 304
+ + TNIA L+ ALI + +VKE+N R+ K+ PIP E I+ V+A +S
Sbjct: 239 FTFIDICKNLPHTNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAIS 298
Query: 305 YGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLK 364
GC ++ + +VG++ GF P++P V +++ +G F +A+V++ + ++ + K
Sbjct: 299 GGCKMPKKYHMQIVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANK 358
Query: 365 YDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIV 424
+ Y +D NQE+IALG N F+ ALS + + GGK+Q+A L +++V+I
Sbjct: 359 HGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMIT 418
Query: 425 VLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGL 484
+L +G L PL KSVL AL NLK L Q + LWRK K DC IW+++F+ + L L
Sbjct: 419 MLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSL 478
Query: 485 GLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPI 544
G+A VAF +L +VF+TQF LA + T+IY N K Y + +G+KI SP+
Sbjct: 479 PYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPL 538
Query: 545 YFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRK------LQKQGLLQVTPKGFICTV 598
YFAN FR+K+I G P ++L + K L+K K Q++ L T + +
Sbjct: 539 YFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQEL 598
Query: 599 DTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN----DDLPLNIEVPK----------- 643
++ D N + + + + F D + + P + E P
Sbjct: 599 QQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPP 658
Query: 644 -ISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFF-D 701
++ H+LILD S VSF+D+ ++ L + + +I V V++V ++ F D
Sbjct: 659 FVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFED 718
Query: 702 GEVKSSIFFLTIHDAVL 718
G ++ F +IHDAVL
Sbjct: 719 GSLECKHVFPSIHDAVL 735
>gi|45827802 prestin isoform c [Homo sapiens]
Length = 516
Score = 429 bits (1104), Expect = e-120
Identities = 224/500 (44%), Positives = 319/500 (63%), Gaps = 13/500 (2%)
Query: 8 QYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAY 67
+Y V RP++S +E + + D LK +C+P+K + I+ PI WLPAY
Sbjct: 15 RYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAY 74
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+ KE++L D+VSGISTG++ + QGLAFA+L +PP++GLY+SF+P I+Y F GTSRHIS+
Sbjct: 75 KFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISI 134
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
GPF ++S+M+G G + VPD G+ N +N + D RV+VA SVT+LSG
Sbjct: 135 GPFAVISLMIG----GVAVRLVPDDIVIPGGV-NATNGTEARDALRVKVAM--SVTLLSG 187
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
IIQ G+ R GFV IYL+E L+ GFTTAAAVHV S LK++F + ++ IF V+
Sbjct: 188 IIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYS---GIFSVV 244
Query: 248 YS---VFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVS 304
YS V ++ N+ L L+V ++ KE N+RFK+KLP PIP+EF V+ G+S
Sbjct: 245 YSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGIS 304
Query: 305 YGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLK 364
G + K + V VVG + G PP PD F D IA+V F+V S+A + K
Sbjct: 305 AGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANK 364
Query: 365 YDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIV 424
+ Y +DGNQELIALGL N + +F+ F+ S +LSRS VQE TGGKTQ+AG + ++++L+V
Sbjct: 365 HGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLV 424
Query: 425 VLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGL 484
+LA GFL L ++VL+A+ + NLKGM MQF+++ WR K + IW+ TF+ ++ LGL
Sbjct: 425 ILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGL 484
Query: 485 GLGLAASVAFQLLTIVFRTQ 504
GL +V LLT+++RTQ
Sbjct: 485 DYGLITAVIIALLTVIYRTQ 504
>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
Length = 739
Score = 399 bits (1024), Expect = e-111
Identities = 225/712 (31%), Positives = 384/712 (53%), Gaps = 53/712 (7%)
Query: 23 ENHKKTGRHHKTF-LDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGI 81
E +K+ + K F + L+ C CSP KAK ++L P+ WLP Y LK+ +L D++SG+
Sbjct: 57 ERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGL 116
Query: 82 STGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAV 141
GI+ V Q +A++LL PVYGLY SFF +IIY GTSRHISVG F +L +M+G V
Sbjct: 117 IVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETV 176
Query: 142 SGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVA--------AAASVTVLSGIIQLAF 193
+ KA D + L SN S+LL+ R+ ++VT ++G+ Q+A
Sbjct: 177 DRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAM 236
Query: 194 GILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQ 253
G ++GFV +YLS++L+SGF T A+ +L SQ K++ L +P S+ VF
Sbjct: 237 GFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRN 296
Query: 254 IEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRF 313
I KTN+ DL+T+L+ LLV+ KE+N+ FK KL PIPIE ++ V A S+ +
Sbjct: 297 IHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENY 356
Query: 314 KVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQ 373
++ G + GF PP P+ + D I+++ FA+ S++ +++ K+ Y + NQ
Sbjct: 357 NSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQ 416
Query: 374 ELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLA 433
E+ A+G NI+ F F S AL+++ V+ESTG TQ++G++ A+++L+V+L I L
Sbjct: 417 EMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFY 476
Query: 434 PLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVA 493
LQKSVL + + NL+G L +F ++ ++W + D +IW +T + + +L +GL V
Sbjct: 477 SLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVC 536
Query: 494 FQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFR 553
F + ++ RTQ PK S L + + ++++ Y ++ G+KIFR +P+Y+ N F+
Sbjct: 537 FSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFK 596
Query: 554 RKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQI 613
L +P+ I KA + RK++++ + T+ I+
Sbjct: 597 SALYKQT-VNPILIKVAWKKAAK--RKIKEK----------VVTLGGIQ----------- 632
Query: 614 EVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQE 673
D++ + + + LH++++D SA+ FLD + + LK + ++
Sbjct: 633 -------------------DEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTLKEVRRD 673
Query: 674 FIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKD 725
+ I + V + + + L E+ E + ++ F ++++A+ + K+
Sbjct: 674 YEAIGIQVLLAQCNPTVRDSLTNGEYCKKE-EENLLFYSVYEAMAFAEVSKN 724
>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 347 bits (891), Expect = 2e-95
Identities = 191/527 (36%), Positives = 304/527 (57%), Gaps = 10/527 (1%)
Query: 43 CSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPP 102
CSCS + +V L P WL YR +E+L D++SG+ GI+ V Q +A++LL + P
Sbjct: 39 CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQP 98
Query: 103 VYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNN 162
+Y LY SFF +IY GTSRH+SVG F +L +MVG V + A D + L N
Sbjct: 99 IYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGAN 158
Query: 163 SN----NSSLLDDER----VRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFT 214
S+ ++++LD R +RVA A +T+++G+ Q+ G+LR+GFV YLS+ L+ GF
Sbjct: 159 SSTLNGSAAMLDCGRDCYAIRVATA--LTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFA 216
Query: 215 TAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSI 274
A+V +L SQLK + + +P H P + S+ + N+ D+VT+ + L V+
Sbjct: 217 MGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLA 276
Query: 275 VKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVE 334
KE++ R++ +L VP+P E ++ V+A VS+ RF +V GD+ GF PP P+
Sbjct: 277 AKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPR 336
Query: 335 TFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGS 394
Q D +A+VA A + S+A +++ + Y + NQEL+A+G N++ FA S
Sbjct: 337 LMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATS 396
Query: 395 TALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQ 454
AL++S V+ +TG +TQ++ ++ A +VL+V+LA+ L LQ+SVLA + + +L+G L +
Sbjct: 397 AALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRK 456
Query: 455 FAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANI 514
++ RLWR D L+W T +++ GL A V LL++ RTQ P+ + LA I
Sbjct: 457 VWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARI 516
Query: 515 GRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVG 561
G T Y++ ++ + GV++FR P+Y+AN FF + L G
Sbjct: 517 GDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTG 563
>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 347 bits (891), Expect = 2e-95
Identities = 191/527 (36%), Positives = 304/527 (57%), Gaps = 10/527 (1%)
Query: 43 CSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPP 102
CSCS + +V L P WL YR +E+L D++SG+ GI+ V Q +A++LL + P
Sbjct: 39 CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQP 98
Query: 103 VYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNN 162
+Y LY SFF +IY GTSRH+SVG F +L +MVG V + A D + L N
Sbjct: 99 IYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGAN 158
Query: 163 SN----NSSLLDDER----VRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFT 214
S+ ++++LD R +RVA A +T+++G+ Q+ G+LR+GFV YLS+ L+ GF
Sbjct: 159 SSTLNGSAAMLDCGRDCYAIRVATA--LTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFA 216
Query: 215 TAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSI 274
A+V +L SQLK + + +P H P + S+ + N+ D+VT+ + L V+
Sbjct: 217 MGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLA 276
Query: 275 VKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVE 334
KE++ R++ +L VP+P E ++ V+A VS+ RF +V GD+ GF PP P+
Sbjct: 277 AKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPR 336
Query: 335 TFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGS 394
Q D +A+VA A + S+A +++ + Y + NQEL+A+G N++ FA S
Sbjct: 337 LMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATS 396
Query: 395 TALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQ 454
AL++S V+ +TG +TQ++ ++ A +VL+V+LA+ L LQ+SVLA + + +L+G L +
Sbjct: 397 AALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRK 456
Query: 455 FAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANI 514
++ RLWR D L+W T +++ GL A V LL++ RTQ P+ + LA I
Sbjct: 457 VWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARI 516
Query: 515 GRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVG 561
G T Y++ ++ + GV++FR P+Y+AN FF + L G
Sbjct: 517 GDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTG 563
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 328 bits (840), Expect = 1e-89
Identities = 214/669 (31%), Positives = 337/669 (50%), Gaps = 53/669 (7%)
Query: 59 PIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLF 118
PI W P Y LKE LL D VSGI + V QGLAFA+L + PV+GLY S FPAIIY
Sbjct: 33 PILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYAI 92
Query: 119 FGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAA 178
FG H++ G F + S++ + AV + VP +N L +N++ L D E R+
Sbjct: 93 FGMGHHVATGTFALTSLIS----ANAVERIVP-QNMQNLTTQSNTSVLGLSDFEMQRIHV 147
Query: 179 AASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHT 238
AA+V+ L G+IQ+A +L++G ++E +IS TT AA HV+ SQ+K++ + +P +
Sbjct: 148 AAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYIS 207
Query: 239 DPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTV 298
P+ F + VF I+ + L+ +L+ ++V+ +VKE+N++FK K+ V +P++ ++ +
Sbjct: 208 GPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLII 267
Query: 299 IAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVA 358
A+ Y + +N + + VVG + G P P + + + FG+A+V + + ++A
Sbjct: 268 AASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALA 327
Query: 359 SVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGA 418
+ K+ Y +D NQE +A GL NIV F + A+ R+A STG KTQ+A LI
Sbjct: 328 QGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISC 387
Query: 419 IIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIF 478
I VLIV+ AIG LL L VLA++ + LKGML+QF ++ + W DK D IW+ T++F
Sbjct: 388 IFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVF 447
Query: 479 TIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIF 538
TI +GL V + ++ R FP+ T++ + K D + VKI
Sbjct: 448 TICFAANVGLLFGVVCTIAIVIGR--FPRAMTVSIKNMKEMEFKVKTEMDSETLQQVKII 505
Query: 539 RCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTV 598
+P+ F N F L + +++K N + + + K C
Sbjct: 506 SINNPLVFLNAKKFYTDL--------MNMIQKENACNQPLDDISK------------CEQ 545
Query: 599 DTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSF 658
+T+ +S L N + N++ + K LILD S +F
Sbjct: 546 NTLLNS---LSNG------------------NCNEEASQSCPNEKC---YLILDCSGFTF 581
Query: 659 LDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVL 718
D S V L + + VDV + I+ + Y D E IFF ++ A+
Sbjct: 582 FDYSGVSMLVEVYMDCKGRSVDVLLAHCTASLIKAMTYYGNLDSE--KPIFFESVSAAIS 639
Query: 719 HILMKKDYS 727
HI K+ S
Sbjct: 640 HIHSNKNLS 648
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 326 bits (836), Expect = 4e-89
Identities = 213/666 (31%), Positives = 335/666 (50%), Gaps = 53/666 (7%)
Query: 59 PIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLF 118
PI W P Y LKE LL D VSGI + V QGLAFA+L + PV+GLY S FPAIIY
Sbjct: 33 PILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYAI 92
Query: 119 FGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAA 178
FG H++ G F + S++ + AV + VP +N L +N++ L D E R+
Sbjct: 93 FGMGHHVATGTFALTSLIS----ANAVERIVP-QNMQNLTTQSNTSVLGLSDFEMQRIHV 147
Query: 179 AASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHT 238
AA+V+ L G+IQ+A +L++G ++E +IS TT AA HV+ SQ+K++ + +P +
Sbjct: 148 AAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYLLGMKMPYIS 207
Query: 239 DPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTV 298
P+ F + VF I+ + L+ +L+ ++V+ +VKE+N++FK K+ V +P++ ++ +
Sbjct: 208 GPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVVLPVDLVLII 267
Query: 299 IAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVA 358
A+ Y + +N + + VVG + G P P + + + FG+A+V + + ++A
Sbjct: 268 AASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALVGYVASLALA 327
Query: 359 SVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGA 418
+ K+ Y +D NQE +A GL NIV F + A+ R+A STG KTQ+A LI
Sbjct: 328 QGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAKTQVACLISC 387
Query: 419 IIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIF 478
I VLIV+ AIG LL L VLA++ + LKGML+QF ++ + W DK D IW+ T++F
Sbjct: 388 IFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVF 447
Query: 479 TIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIF 538
TI +GL V + ++ R FP+ T++ + K D + VKI
Sbjct: 448 TICFAANVGLLFGVVCTIAIVIGR--FPRAMTVSIKNMKEMEFKVKTEMDSETLQQVKII 505
Query: 539 RCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTV 598
+P+ F N F L + +++K N + + + K C
Sbjct: 506 SINNPLVFLNAKKFYTDL--------MNMIQKENACNQPLDDISK------------CEQ 545
Query: 599 DTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSF 658
+T+ +S L N + N++ + K LILD S +F
Sbjct: 546 NTLLNS---LSNG------------------NCNEEASQSCPNEKC---YLILDCSGFTF 581
Query: 659 LDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVL 718
D S V L + + VDV + I+ + Y D E IFF ++ A+
Sbjct: 582 FDYSGVSMLVEVYMDCKGRSVDVLLAHCTASLIKAMTYYGNLDSE--KPIFFESVSAAIS 639
Query: 719 HILMKK 724
HI K
Sbjct: 640 HIHSNK 645
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 314 bits (805), Expect = 2e-85
Identities = 194/570 (34%), Positives = 308/570 (54%), Gaps = 32/570 (5%)
Query: 9 YIVARPVYSTNAFEENHKKTGRHH-------KTFLDHLKVCCSCSPQKAKRIVLSLFPIA 61
Y V R VY+ F++ HK+ TF H++ C CS + R VL++FP
Sbjct: 23 YDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHVQ--CRCSWHRFLRCVLTIFPFL 80
Query: 62 SWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVD--IPPVYGLYASFFPAIIYLFF 119
W+ YRLK+WLL D+++GIS G+V V QGL +LL IPP+ YA+F ++IY+ F
Sbjct: 81 EWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIF 140
Query: 120 GTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLG---LPNNSNNSSLLDDERVRV 176
G+ +S+G F ++S A+ V K P N + + N + S L +
Sbjct: 141 GSCHQMSIGSFFLVS-----ALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSL 195
Query: 177 AAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPS 236
+ A+ T L+GIIQL G+L +GF+ YL ES +S + A A+H+++SQL FIF + +
Sbjct: 196 SVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISF 255
Query: 237 HTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIM 296
H P+S F + + + K N ++ L V++ + I K I F ++ P+ P+E +
Sbjct: 256 HAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISF-NQYPIEFPMELFL 314
Query: 297 ----TVIAAGVSYGCDFKNRFKVAVVGDMNP-GFQPPITPDVETFQNTVGDCFGIAMVA- 350
TVIA +S + + DM P F P+TPD + F +++V+
Sbjct: 315 IIGFTVIANKISMATETSQ-----TLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSS 369
Query: 351 FAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKT 410
F + F + SL ++Y ++ NQ+LIA+GL N+V FR + A++R+ +Q+ +GG+
Sbjct: 370 FLLIFLGKKIASL-HNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQ 428
Query: 411 QIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCL 470
Q A L+GA ++L++++ +G L +VLA + L N+ L + + LWR+D+YDC
Sbjct: 429 QFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCA 488
Query: 471 IWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMY 530
+W+MTF +I LGL +GL SV R+ K L I TNIY++ DY ++
Sbjct: 489 LWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREII 548
Query: 531 EPEGVKIFRCPSPIYFANIGFFRRKLIDAV 560
GVKIF+C S I F N+ + + KL+ V
Sbjct: 549 TIPGVKIFQCCSSITFVNVYYLKHKLLKEV 578
Score = 57.4 bits (137), Expect = 5e-08
Identities = 28/88 (31%), Positives = 47/88 (53%)
Query: 645 SLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEV 704
S+H++ILDFS V ++D + L+ I F + + I G + R +FFD +
Sbjct: 720 SVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGI 779
Query: 705 KSSIFFLTIHDAVLHILMKKDYSTSKFN 732
+ FL++HDAVL L +K +S+ +
Sbjct: 780 TKTQLFLSVHDAVLFALSRKVIGSSELS 807
>gi|45827804 prestin isoform d [Homo sapiens]
Length = 335
Score = 269 bits (688), Expect = 6e-72
Identities = 143/326 (43%), Positives = 203/326 (62%), Gaps = 13/326 (3%)
Query: 8 QYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAY 67
+Y V RP++S +E + + D LK +C+P+K + I+ PI WLPAY
Sbjct: 15 RYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAY 74
Query: 68 RLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISV 127
+ KE++L D+VSGISTG++ + QGLAFA+L +PP++GLY+SF+P I+Y F GTSRHIS+
Sbjct: 75 KFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISI 134
Query: 128 GPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSG 187
GPF ++S+M+G G + VPD + G N +N + D RV+V A SVT+LSG
Sbjct: 135 GPFAVISLMIG----GVAVRLVPD-DIVIPGGVNATNGTEARDALRVKV--AMSVTLLSG 187
Query: 188 IIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVL 247
IIQ G+ R GFV IYL+E L+ GFTTAAAVHV S LK++F + ++ IF V+
Sbjct: 188 IIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYS---GIFSVV 244
Query: 248 YS---VFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVS 304
YS V ++ N+ L L+V ++ KE N+RFK+KLP PIP+EF V+ G+S
Sbjct: 245 YSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGIS 304
Query: 305 YGCDFKNRFKVAVVGDMNPGFQPPIT 330
G + K + V VVG + GF +T
Sbjct: 305 AGFNLKESYNVDVVGTLPLGFHTEMT 330
>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
Length = 563
Score = 260 bits (664), Expect = 4e-69
Identities = 146/404 (36%), Positives = 232/404 (57%), Gaps = 10/404 (2%)
Query: 70 KEWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGP 129
K W L S T + G+AFALL +PPV+GLY SFFP +IY GT RH+S G
Sbjct: 20 KSWRLDKAPSPQHTFPSTSIPGMAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGT 79
Query: 130 FPILSMMVGLAVSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGII 189
F ILS+M G AV + VP+ L + LD +RV VAAA V SG +
Sbjct: 80 FAILSLMTG----SAVERLVPEPLVGNL----SGIEKEQLDAQRVGVAAA--VAFGSGAL 129
Query: 190 QLAFGILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYS 249
L +L++G + +LSE ++ T+ AA+HVL+SQL + L++P S+FK L S
Sbjct: 130 MLGMFVLQLGVLSTFLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLAS 189
Query: 250 VFSQIEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDF 309
+ + + +++ A+L + + L ++ VKE+N RF+D+LP PIP E ++ ++A+ + +
Sbjct: 190 LLTALPRSSPAELTISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSV 249
Query: 310 KNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPL 369
R++V +VG + GF P+ P++ + D IA+V+FAV+ S+AS+++ KY Y +
Sbjct: 250 DTRYQVQIVGLLPGGFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTI 309
Query: 370 DGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIG 429
D NQE +A G N++ +F F S L+ + + GGKTQ+AGL +VL V+L +G
Sbjct: 310 DSNQEFLAHGASNLISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLG 369
Query: 430 FLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWI 473
L K+VLA + + +++ + Q E+ +LW + D L+ +
Sbjct: 370 PFFYYLPKAVLACINISSMRQVFCQMQELPQLWHISRVDFLLQV 413
>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
Length = 459
Score = 206 bits (524), Expect = 7e-53
Identities = 129/402 (32%), Positives = 204/402 (50%), Gaps = 23/402 (5%)
Query: 340 VGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSR 399
+G F +A+V++ + ++ + K+ Y +D NQE+IALG N F+ ALS
Sbjct: 2 IGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSV 61
Query: 400 SAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIG 459
+ + GGK+Q+A L +++V+I +L +G L PL KSVL AL NLK L Q +
Sbjct: 62 TLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPY 121
Query: 460 RLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNI 519
LWRK K DC IW+++F+ + L L G+A VAF +L +VF+TQF LA + T+I
Sbjct: 122 YLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDI 181
Query: 520 YKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGFSPLRILRKRNKALRKIR 579
Y N K Y + +G+KI SP+YFAN FR+K+I G P ++L + K L+K
Sbjct: 182 YVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQE 241
Query: 580 K------LQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWN- 632
K Q++ L T + + ++ D N + + + + F D +
Sbjct: 242 KRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSS 301
Query: 633 ---DDLPLNIEVPK------------ISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRI 677
+ P + E P ++ H+LILD S VSF+D+ ++ L + + +I
Sbjct: 302 PAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKI 361
Query: 678 KVDVYIVGTDDDFIEKLNRYEFF-DGEVKSSIFFLTIHDAVL 718
V V++V ++ F DG ++ F +IHDAVL
Sbjct: 362 GVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVL 403
>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
Length = 606
Score = 173 bits (438), Expect = 6e-43
Identities = 137/492 (27%), Positives = 225/492 (45%), Gaps = 69/492 (14%)
Query: 43 CSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPP 102
C CSP +R + PI +WLP+Y L +WL D V+G+S G+ A+ Q LA+A + +PP
Sbjct: 23 CCCSPAALQRRL----PILAWLPSYSL-QWLKMDFVAGLSVGLTAIPQALAYAEVAGLPP 77
Query: 103 VYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTLGLPNN 162
YGLY++F +Y F GTSR +++GP I+S++V T P
Sbjct: 78 QYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFY---------------TFHEP-- 120
Query: 163 SNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLISGFTTAAAVHVL 222
A A + LSG IQLA G+LR+GF++ ++S +I GFT+AAAV +
Sbjct: 121 --------------AYAVLLAFLSGCIQLAMGVLRLGFLLDFISYPVIKGFTSAAAVTIG 166
Query: 223 VSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQRF 282
Q+K + L P F +Y F +I +T + D V L+ +L++ ++K +
Sbjct: 167 FGQIKNLLGL----QNIPRPFFLQVYHTFLRIAETRVGDAVLGLVCMLLLLVLKLMRDHV 222
Query: 283 KDKLPVPIP---------------IEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQP 327
P P ++ AA V+Y + + G+ G P
Sbjct: 223 PPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVAYSFEVTGYQPFILTGETAEGLPP 282
Query: 328 PITPDVE--------TFQNTVGDC-FGIAMV---AFAVAFSVASVYSLKYDYPLDGNQEL 375
P +F V D G+A+V + +VA ++ + +Y +D NQEL
Sbjct: 283 VRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQNNYRIDANQEL 342
Query: 376 IALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPL 435
+A+GL N++ + + + + R+AV +G T GL+ ++VL+ + + L +
Sbjct: 343 LAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSLDYLTSLFYYI 402
Query: 436 QKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQ 495
KS LAA+ + + L LWR + D L +TF+ + G+ A
Sbjct: 403 PKSALAAVIIMAV-APLFDTKIFRTLWRVKRLDLLPLCVTFLLCF-WEVQYGILAGALVS 460
Query: 496 LLTIVFRTQFPK 507
LL ++ P+
Sbjct: 461 LLMLLHSAARPE 472
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 158 bits (400), Expect = 2e-38
Identities = 87/243 (35%), Positives = 139/243 (57%), Gaps = 3/243 (1%)
Query: 320 DMNP-GFQPPITPDVETFQNTVGDCFGIAMVA-FAVAFSVASVYSLKYDYPLDGNQELIA 377
DM P F P+TPD + F +++V+ F + F + SL ++Y ++ NQ+LIA
Sbjct: 232 DMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASL-HNYSVNSNQDLIA 290
Query: 378 LGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPLQK 437
+GL N+V FR + A++R+ +Q+ +GG+ Q A L+GA ++L++++ +G L
Sbjct: 291 IGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPN 350
Query: 438 SVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVAFQLL 497
+VLA + L N+ L + + LWR+D+YDC +W+MTF +I LGL +GL SV
Sbjct: 351 AVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFF 410
Query: 498 TIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLI 557
R+ K L I TNIY++ DY ++ GVKIF+C S I F N+ + + KL+
Sbjct: 411 ITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLL 470
Query: 558 DAV 560
V
Sbjct: 471 KEV 473
Score = 105 bits (263), Expect = 1e-22
Identities = 72/207 (34%), Positives = 108/207 (52%), Gaps = 25/207 (12%)
Query: 9 YIVARPVYSTNAFEENHKKTGRHH-------KTFLDHLKVCCSCSPQKAKRIVLSLFPIA 61
Y V R VY+ F++ HK+ TF H++ C CS + R +L++FP
Sbjct: 23 YDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHVQ--CRCSWHRFLRCMLTIFPFL 80
Query: 62 SWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVD--IPPVYGLYASFFPAIIYLFF 119
W+ YRLK+WLL D+++GIS G+V V QGL +LL IPP+ YA+F ++IY+ F
Sbjct: 81 EWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIF 140
Query: 120 GTSRHISVGPFPILSMMVGLAVSGAVSKAVPDRNATTL---GLPNNSNNSSLLDDERVRV 176
G+ +S+G F ++S A+ V K P N + + N + S L +
Sbjct: 141 GSCHQMSIGSFFLVS-----ALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSL 195
Query: 177 AAAASVTVLSGIIQLAFGILRIGFVVI 203
+ A+ T L+GIIQ+ IGF VI
Sbjct: 196 SVVATTTFLTGIIQI------IGFTVI 216
Score = 57.4 bits (137), Expect = 5e-08
Identities = 28/88 (31%), Positives = 47/88 (53%)
Query: 645 SLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFFDGEV 704
S+H++ILDFS V ++D + L+ I F + + I G + R +FFD +
Sbjct: 615 SVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGI 674
Query: 705 KSSIFFLTIHDAVLHILMKKDYSTSKFN 732
+ FL++HDAVL L +K +S+ +
Sbjct: 675 TKTQLFLSVHDAVLFALSRKVIGSSELS 702
>gi|20336274 solute carrier family 26, member 1 isoform b [Homo
sapiens]
Length = 224
Score = 107 bits (267), Expect = 4e-23
Identities = 59/163 (36%), Positives = 93/163 (57%), Gaps = 16/163 (9%)
Query: 43 CSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGISTGIVAVLQGLAFALLVDIPP 102
CSCS + +V L P WL YR +E+L D++SG+ GI+ V Q +A++LL + P
Sbjct: 39 CSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQP 98
Query: 103 VYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAVSGAVSKA---------VPDRN 153
+Y LY SFF +IY GTSRH+SVG F +L +MVG V + A P N
Sbjct: 99 IYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGAN 158
Query: 154 ATTLGLPNNSNNSSLLDDER--VRVAAAASVTVLSGIIQLAFG 194
++TL + ++++LD R + A ++T+++G+ Q ++G
Sbjct: 159 SSTL-----NGSAAMLDCGRDCYAIRVATALTLMTGLYQTSWG 196
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 32.3 bits (72), Expect = 1.7
Identities = 22/83 (26%), Positives = 33/83 (39%)
Query: 470 LIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDM 529
+++I FI + G L V + + T CS L +I I N D +
Sbjct: 284 ILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPL 343
Query: 530 YEPEGVKIFRCPSPIYFANIGFF 552
Y+ V+ F P Y+ N FF
Sbjct: 344 YDDVKVQFFSSNLPKYYDNCPFF 366
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 32.3 bits (72), Expect = 1.7
Identities = 22/83 (26%), Positives = 33/83 (39%)
Query: 470 LIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDM 529
+++I FI + G L V + + T CS L +I I N D +
Sbjct: 395 ILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPL 454
Query: 530 YEPEGVKIFRCPSPIYFANIGFF 552
Y+ V+ F P Y+ N FF
Sbjct: 455 YDDVKVQFFSSNLPKYYDNCPFF 477
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 32.3 bits (72), Expect = 1.7
Identities = 22/83 (26%), Positives = 33/83 (39%)
Query: 470 LIWIMTFIFTIVLGLGLGLAASVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDM 529
+++I FI + G L V + + T CS L +I I N D +
Sbjct: 318 ILFIKRFIIYSIRGDVCDLKVQVVMEKKVVFSSTSLGNCSILHDIETDKILINVYDGPPL 377
Query: 530 YEPEGVKIFRCPSPIYFANIGFF 552
Y+ V+ F P Y+ N FF
Sbjct: 378 YDDVKVQFFSSNLPKYYDNCPFF 400
>gi|148806891 hypothetical protein LOC54906 [Homo sapiens]
Length = 2430
Score = 31.6 bits (70), Expect = 2.9
Identities = 19/60 (31%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 594 FICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDF 653
F C + D + NN +E T H WN DLP N+E K+ LH + F
Sbjct: 747 FKCETEYAFSLDSKYTNNPLE------KTVVRALHGPWNTDLPDNVEEVKLLLHMWVALF 800
>gi|86792634 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
isoform 2 [Homo sapiens]
Length = 158
Score = 30.8 bits (68), Expect = 4.9
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 376 IALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPL 435
+ +GL N+ CGV G GS A A S K I + G+ I L G ++A L
Sbjct: 95 LTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGL-----FGVIVAIL 149
Query: 436 QKS 438
Q S
Sbjct: 150 QTS 152
>gi|4757816 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
isoform 1 [Homo sapiens]
Length = 205
Score = 30.8 bits (68), Expect = 4.9
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 376 IALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLAPL 435
+ +GL N+ CGV G GS A A S K I + G+ I L G ++A L
Sbjct: 142 LTVGLSNLFCGVCVGIVGSGAALADAQNPSLFVKILIVEIFGSAIGL-----FGVIVAIL 196
Query: 436 QKS 438
Q S
Sbjct: 197 QTS 199
>gi|239748761 PREDICTED: hypothetical protein XP_002346789 [Homo
sapiens]
Length = 513
Score = 30.4 bits (67), Expect = 6.4
Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 12/125 (9%)
Query: 357 VASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGF-----AG--STALSRSAVQESTGGK 409
VAS++S+ + PL+ L G ++ +FR AG S + S + GG
Sbjct: 295 VASIFSMLANSPLESRSTPPLLARGRLLIPLFRPLFFDVPAGPCSVGEAASGLLAGAGGS 354
Query: 410 TQIAGLIGAIIVLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDC 469
GL+ A V VV A+G L ++V+ L + F+ +G + D
Sbjct: 355 LDSFGLVVAAGV-AVVAALGTEPPKLSEAVVLLPVLAGPGSATLVFSRVG----AEDTDE 409
Query: 470 LIWIM 474
+IW M
Sbjct: 410 MIWAM 414
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.141 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,510,222
Number of Sequences: 37866
Number of extensions: 1059080
Number of successful extensions: 3107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 3014
Number of HSP's gapped (non-prelim): 46
length of query: 764
length of database: 18,247,518
effective HSP length: 110
effective length of query: 654
effective length of database: 14,082,258
effective search space: 9209796732
effective search space used: 9209796732
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.