Guide to the Human Genome
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Search of human proteins with 4557471

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557471 adaptor-related protein complex 1, sigma 1 subunit
[Homo sapiens]
         (158 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H...   316   6e-87
gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H...   283   4e-77
gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [...   229   6e-61
gi|70906430 adaptor-related protein complex 2, sigma 1 subunit i...   144   2e-35
gi|189409104 adaptor-related protein complex 4, sigma 1 subunit ...   116   7e-27
gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [H...   111   2e-25
gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [H...   108   2e-24
gi|21361394 adaptor-related protein complex 4, sigma 1 subunit i...    92   2e-19
gi|11038643 adaptor-related protein complex 2, sigma 1 subunit i...    83   1e-16
gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Hom...    38   0.003
gi|68799814 adaptor-related protein complex 2, mu 1 subunit isof...    38   0.004
gi|14917109 adaptor-related protein complex 2, mu 1 subunit isof...    35   0.020
gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo...    35   0.027
gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Hom...    35   0.027
gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Ho...    35   0.027
gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo...    35   0.027
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo...    35   0.027
gi|7706337 coatomer protein complex, subunit zeta 1 [Homo sapiens]     35   0.035
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso...    32   0.29 
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof...    32   0.29 
gi|11863154 archain isoform 1 [Homo sapiens]                           30   1.1  
gi|64085161 thyroid stimulating hormone receptor isoform 2 precu...    28   3.3  
gi|4758638 peroxiredoxin 6 [Homo sapiens]                              28   3.3  
gi|6912626 fascin 2 isoform 1 [Homo sapiens]                           28   3.3  
gi|199560536 hypothetical protein LOC283643 isoform 4 [Homo sapi...    28   4.3  
gi|199560438 hypothetical protein LOC283643 isoform 2 [Homo sapi...    28   4.3  
gi|239757058 PREDICTED: hypothetical protein [Homo sapiens]            27   7.3  
gi|110347443 TATA element modulatory factor 1 [Homo sapiens]           27   7.3  
gi|196114970 protein tyrosine phosphatase, non-receptor type 12 ...    27   9.5  
gi|196114967 protein tyrosine phosphatase, non-receptor type 12 ...    27   9.5  

>gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo
           sapiens]
          Length = 158

 Score =  316 bits (809), Expect = 6e-87
 Identities = 158/158 (100%), Positives = 158/158 (100%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK
Sbjct: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120
           RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG
Sbjct: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120

Query: 121 GDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA 158
           GDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
Sbjct: 121 GDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA 158


>gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo
           sapiens]
          Length = 157

 Score =  283 bits (724), Expect = 4e-77
 Identities = 137/156 (87%), Positives = 150/156 (96%)

Query: 2   MRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKR 61
           M+FMLLFSRQGKLRLQKWY+  SDKE+KK+ REL+Q VLARKPKMCSFLEWRDLK+VYKR
Sbjct: 1   MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR 60

Query: 62  YASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGG 121
           YASLYFCCAIE QDNELITLE+IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFL+GG
Sbjct: 61  YASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGG 120

Query: 122 DVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGL 157
           +VQ+TSKK+VLKAIEQADLLQEE E+PRSVLEE+GL
Sbjct: 121 EVQETSKKNVLKAIEQADLLQEEAETPRSVLEEIGL 156


>gi|88703051 adaptor-related protein complex 1, sigma 3 subunit
           [Homo sapiens]
          Length = 154

 Score =  229 bits (585), Expect = 6e-61
 Identities = 104/146 (71%), Positives = 131/146 (89%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           M+ F+LLFSRQGKLRLQKWY+   DKERKK+ RE++Q++L+R  +  SF++W++LK+VYK
Sbjct: 1   MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYK 60

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120
           RYASLYFCCAIE QDNEL+TLE++HRYVELLDKYFG+VCELDIIFNFEKAYFILDEF++G
Sbjct: 61  RYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG 120

Query: 121 GDVQDTSKKSVLKAIEQADLLQEEDE 146
           G++Q+TSKK  +KAIE +D+LQE  E
Sbjct: 121 GEIQETSKKIAVKAIEDSDMLQETME 146


>gi|70906430 adaptor-related protein complex 2, sigma 1 subunit
           isoform AP17 [Homo sapiens]
          Length = 142

 Score =  144 bits (364), Expect = 2e-35
 Identities = 62/135 (45%), Positives = 97/135 (71%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           M+RF+L+ +R GK RL KWY+   D E++K++ E+  VV  R  K  +F+E+R+ K++Y+
Sbjct: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYR 60

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120
           RYA LYFC  ++  DN L  LE IH +VE+L++YF +VCELD++FNF K Y ++DE  + 
Sbjct: 61  RYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA 120

Query: 121 GDVQDTSKKSVLKAI 135
           G++++TS+  VLK +
Sbjct: 121 GEIRETSQTKVLKQL 135


>gi|189409104 adaptor-related protein complex 4, sigma 1 subunit
           isoform 2 [Homo sapiens]
          Length = 144

 Score =  116 bits (291), Expect = 7e-27
 Identities = 51/143 (35%), Positives = 92/143 (64%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           M++F L+ ++QG+ RL K+Y      +R  +  E+++  L+R  + CSF+E++D K++Y+
Sbjct: 1   MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYR 60

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120
           +YA+L+    +   +NE+   E IH +VE+LD+YF  V ELDI+FN +K + ILDE ++ 
Sbjct: 61  QYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEMVLN 120

Query: 121 GDVQDTSKKSVLKAIEQADLLQE 143
           G + +T++  +L  +   D + E
Sbjct: 121 GCIVETNRARILAPLLILDKMSE 143


>gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [Homo
           sapiens]
          Length = 193

 Score =  111 bits (278), Expect = 2e-25
 Identities = 56/151 (37%), Positives = 97/151 (64%), Gaps = 6/151 (3%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEW------RD 54
           M++ +L+F+  GK RL ++Y    ++ ++++VRE   +VL R   +C+FLE        D
Sbjct: 1   MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60

Query: 55  LKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFIL 114
            K++Y+ YA+LYF   ++  ++EL  L+LI  +VE LDK F +VCELD+IF+ +K ++IL
Sbjct: 61  YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120

Query: 115 DEFLMGGDVQDTSKKSVLKAIEQADLLQEED 145
            E +MGG V +T+   ++  IE  + L++ +
Sbjct: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLEKSE 151


>gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [Homo
           sapiens]
          Length = 193

 Score =  108 bits (270), Expect = 2e-24
 Identities = 55/151 (36%), Positives = 95/151 (62%), Gaps = 6/151 (3%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEW------RD 54
           M++ +L+F+  GK RL K+Y   S+  +++++RE   +V  R   +C+FLE        D
Sbjct: 1   MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSD 60

Query: 55  LKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFIL 114
            K++Y+ YA+LYF   ++  ++EL  L+LI  +VE LDK F +VCELD+IF+ +K + IL
Sbjct: 61  NKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNIL 120

Query: 115 DEFLMGGDVQDTSKKSVLKAIEQADLLQEED 145
            E +MGG V +T+   ++  I+  + L++ +
Sbjct: 121 AEMVMGGMVLETNMNEIVTQIDAQNKLEKSE 151


>gi|21361394 adaptor-related protein complex 4, sigma 1 subunit
           isoform 1 [Homo sapiens]
          Length = 159

 Score = 92.0 bits (227), Expect = 2e-19
 Identities = 39/105 (37%), Positives = 69/105 (65%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           M++F L+ ++QG+ RL K+Y      +R  +  E+++  L+R  + CSF+E++D K++Y+
Sbjct: 1   MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYR 60

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIF 105
           +YA+L+    +   +NE+   E IH +VE+LD+YF  V ELD+ F
Sbjct: 61  QYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDVSF 105


>gi|11038643 adaptor-related protein complex 2, sigma 1 subunit
           isoform AP17delta [Homo sapiens]
          Length = 104

 Score = 82.8 bits (203), Expect = 1e-16
 Identities = 44/135 (32%), Positives = 70/135 (51%), Gaps = 38/135 (28%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           M+RF+L+ +R GK RL KWY+   D E++K++ E+  VV  R  K  +F           
Sbjct: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNF----------- 49

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120
                                      VE+L++YF +VCELD++FNF K Y ++DE  + 
Sbjct: 50  ---------------------------VEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA 82

Query: 121 GDVQDTSKKSVLKAI 135
           G++++TS+  VLK +
Sbjct: 83  GEIRETSQTKVLKQL 97


>gi|14917111 adaptor-related protein complex 4, mu 1 subunit [Homo
           sapiens]
          Length = 453

 Score = 38.1 bits (87), Expect = 0.003
 Identities = 26/79 (32%), Positives = 37/79 (46%)

Query: 58  VYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEF 117
           ++ R++ LY         +    LEL+ R   LL  Y GS+ E  I  N    Y +LDE 
Sbjct: 57  IHIRHSGLYLVVTTSENVSPFSLLELLSRLATLLGDYCGSLGEGTISRNVALVYELLDEV 116

Query: 118 LMGGDVQDTSKKSVLKAIE 136
           L  G VQ TS + +   I+
Sbjct: 117 LDYGYVQTTSTEMLRNFIQ 135


>gi|68799814 adaptor-related protein complex 2, mu 1 subunit isoform
           b [Homo sapiens]
          Length = 433

 Score = 37.7 bits (86), Expect = 0.004
 Identities = 27/155 (17%), Positives = 67/155 (43%), Gaps = 2/155 (1%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           M+  + +++ +G++ + + Y    D  R  +    + V+ AR+               + 
Sbjct: 1   MIGGLFIYNHKGEVLISRVY--RDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHV 58

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120
           + ++++     +   N  +  E +++  +++  YFG + E +I  NF   Y +LDE L  
Sbjct: 59  KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF 118

Query: 121 GDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEM 155
           G  Q++   ++   I Q  +  +  E    +  ++
Sbjct: 119 GYPQNSETGALKTFITQQGIKSQTKEEQSQITSQV 153


>gi|14917109 adaptor-related protein complex 2, mu 1 subunit isoform
           a [Homo sapiens]
          Length = 435

 Score = 35.4 bits (80), Expect = 0.020
 Identities = 26/137 (18%), Positives = 61/137 (44%), Gaps = 2/137 (1%)

Query: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60
           M+  + +++ +G++ + + Y    D  R  +    + V+ AR+               + 
Sbjct: 1   MIGGLFIYNHKGEVLISRVY--RDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHV 58

Query: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120
           + ++++     +   N  +  E +++  +++  YFG + E +I  NF   Y +LDE L  
Sbjct: 59  KRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDF 118

Query: 121 GDVQDTSKKSVLKAIEQ 137
           G  Q++   ++   I Q
Sbjct: 119 GYPQNSETGALKTFITQ 135


>gi|6912240 adaptor-related protein complex 3, mu 1 subunit [Homo
           sapiens]
          Length = 418

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 21/78 (26%), Positives = 34/78 (43%)

Query: 65  LYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQ 124
           L+F   I+ +   L  +E +HR  +    YFG   E  I  N    Y +L+E L  G   
Sbjct: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123

Query: 125 DTSKKSVLKAIEQADLLQ 142
            T    + + I+   +L+
Sbjct: 124 ATESNILKELIKPPTILR 141


>gi|46370095 adaptor-related protein complex 3, mu 1 subunit [Homo
           sapiens]
          Length = 418

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 21/78 (26%), Positives = 34/78 (43%)

Query: 65  LYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQ 124
           L+F   I+ +   L  +E +HR  +    YFG   E  I  N    Y +L+E L  G   
Sbjct: 64  LFFVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSEAAIKDNVVIVYELLEEMLDNGFPL 123

Query: 125 DTSKKSVLKAIEQADLLQ 142
            T    + + I+   +L+
Sbjct: 124 ATESNILKELIKPPTILR 141


>gi|197209857 adaptor-related protein complex 3, mu 2 subunit [Homo
           sapiens]
          Length = 418

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 21/78 (26%), Positives = 35/78 (44%)

Query: 65  LYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQ 124
           ++F   I+ +   L  +E +HR V+    YFG   E  I  N    Y +L+E L  G   
Sbjct: 64  IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123

Query: 125 DTSKKSVLKAIEQADLLQ 142
            T    + + I+   +L+
Sbjct: 124 ATESNILKELIKPPTILR 141


>gi|5803000 adaptor-related protein complex 3, mu 2 subunit [Homo
           sapiens]
          Length = 418

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 21/78 (26%), Positives = 35/78 (44%)

Query: 65  LYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQ 124
           ++F   I+ +   L  +E +HR V+    YFG   E  I  N    Y +L+E L  G   
Sbjct: 64  IFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPL 123

Query: 125 DTSKKSVLKAIEQADLLQ 142
            T    + + I+   +L+
Sbjct: 124 ATESNILKELIKPPTILR 141


>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
           sapiens]
          Length = 423

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 23/108 (21%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 32  VRELMQVVLARKPK--MCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVE 89
           +   M +++ R+ +  +   L    +  ++ ++++LY         N  +    +++ +E
Sbjct: 30  IEHFMPLLVQREEEGALAPLLSHGQVHFLWIKHSNLYLVATTSKNANASLVYSFLYKTIE 89

Query: 90  LLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQ 137
           +  +YF  + E  I  NF   Y +LDE +  G  Q T  K + + I Q
Sbjct: 90  VFCEYFKELEEESIRDNFVIVYELLDELMDFGFPQTTDSKILQEYITQ 137


>gi|7706337 coatomer protein complex, subunit zeta 1 [Homo sapiens]
          Length = 177

 Score = 34.7 bits (78), Expect = 0.035
 Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 6/137 (4%)

Query: 2   MRFMLLFSRQGKLRLQKWYLAT--SDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVY 59
           ++ +L+    G     K+Y  T  S KE+K   + +      R     + LE   L VVY
Sbjct: 13  VKAILILDNDGDRLFAKYYDDTYPSVKEQKAFEKNIFNKT-HRTDSEIALLE--GLTVVY 69

Query: 60  KRYASLYFCCAIEGQDNELITLELIHRYVELLDKYF-GSVCELDIIFNFEKAYFILDEFL 118
           K    LYF       +NEL+ + +++   + L +    +V +  ++ N E  +  +DE +
Sbjct: 70  KSSIDLYFYVIGSSYENELMLMAVLNCLFDSLSQMLRKNVEKRALLENMEGLFLAVDEIV 129

Query: 119 MGGDVQDTSKKSVLKAI 135
            GG + ++  + V+  +
Sbjct: 130 DGGVILESDPQQVVHRV 146


>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
           isoform 1 [Homo sapiens]
          Length = 435

 Score = 31.6 bits (70), Expect = 0.29
 Identities = 26/129 (20%), Positives = 57/129 (44%), Gaps = 5/129 (3%)

Query: 11  QGKLRLQKWYLATSDKERKKMVRELMQVVLARKPK--MCSFLEWRDLKVVYKRYASLYFC 68
           +GK+ + + Y    D      V   M +++ ++ +  +   L    ++ ++ ++ +LY  
Sbjct: 12  KGKVLICRNYRGDVDMSE---VEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLV 68

Query: 69  CAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSK 128
              +      +    +++ V++  +YF  + E  I  NF   Y +LDE +  G  Q T  
Sbjct: 69  ATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS 128

Query: 129 KSVLKAIEQ 137
           K + + I Q
Sbjct: 129 KILQEYITQ 137


>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
           2 [Homo sapiens]
          Length = 423

 Score = 31.6 bits (70), Expect = 0.29
 Identities = 26/129 (20%), Positives = 57/129 (44%), Gaps = 5/129 (3%)

Query: 11  QGKLRLQKWYLATSDKERKKMVRELMQVVLARKPK--MCSFLEWRDLKVVYKRYASLYFC 68
           +GK+ + + Y    D      V   M +++ ++ +  +   L    ++ ++ ++ +LY  
Sbjct: 12  KGKVLICRNYRGDVDMSE---VEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLV 68

Query: 69  CAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGGDVQDTSK 128
              +      +    +++ V++  +YF  + E  I  NF   Y +LDE +  G  Q T  
Sbjct: 69  ATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDS 128

Query: 129 KSVLKAIEQ 137
           K + + I Q
Sbjct: 129 KILQEYITQ 137


>gi|11863154 archain isoform 1 [Homo sapiens]
          Length = 511

 Score = 29.6 bits (65), Expect = 1.1
 Identities = 29/143 (20%), Positives = 57/143 (39%), Gaps = 19/143 (13%)

Query: 30  KMVRELMQVVLARKPKMCS------FLEWRDLKVVYKRYASLYFCCAIEGQDNELITLEL 83
           +M R  ++ +LA  PK+ +      F+E   ++ VY+    LY         N L  LE 
Sbjct: 23  EMTRTRIEGLLAAFPKLMNTGKQHTFVETESVRYVYQPMEKLYMVLITTKNSNILEDLET 82

Query: 84  IHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMGG-------------DVQDTSKKS 130
           +  +  ++ +Y  ++ E +I  +     F  DE +  G                D+ ++ 
Sbjct: 83  LRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGYRENVNLAQIRTFTEMDSHEEK 142

Query: 131 VLKAIEQADLLQEEDESPRSVLE 153
           V +A+ +    + + E  R   E
Sbjct: 143 VFRAVRETQEREAKAEMRRKAKE 165


>gi|64085161 thyroid stimulating hormone receptor isoform 2
           precursor [Homo sapiens]
          Length = 253

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 4/82 (4%)

Query: 70  AIEGQDNELITLELIHRYVELLDKYFGSVCELDIIF-NFEKAYFILDEFLMGGDVQDTSK 128
           A +G  NE +TL+L +     +  Y  +  +LD ++ N  K   ++D+   GG     S 
Sbjct: 171 AFQGLCNETLTLKLYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVY---SG 227

Query: 129 KSVLKAIEQADLLQEEDESPRS 150
            S+L  + +  L  E  ++PRS
Sbjct: 228 PSLLLPLGRKSLSFETQKAPRS 249


>gi|4758638 peroxiredoxin 6 [Homo sapiens]
          Length = 224

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 12/52 (23%), Positives = 30/52 (57%)

Query: 3   RFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRD 54
           R + +F    KL+L   Y AT+ +   +++R ++ + L  + ++ + ++W+D
Sbjct: 132 RVVFVFGPDKKLKLSILYPATTGRNFDEILRVVISLQLTAEKRVATPVDWKD 183


>gi|6912626 fascin 2 isoform 1 [Homo sapiens]
          Length = 492

 Score = 28.1 bits (61), Expect = 3.3
 Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 9/59 (15%)

Query: 50  LEWRDLKVVYKRYASLYFCCAIEGQ---------DNELITLELIHRYVELLDKYFGSVC 99
           +EWR  +V  K     Y C    GQ          +E  TL+LI+R + +L    G VC
Sbjct: 336 MEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVC 394


>gi|199560536 hypothetical protein LOC283643 isoform 4 [Homo
           sapiens]
          Length = 352

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 13/51 (25%), Positives = 30/51 (58%)

Query: 12  GKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRY 62
           GKLR +   L +S +E+  ++ +L++ +     ++ + L WR  ++V+ R+
Sbjct: 132 GKLRFRWRQLVSSQQEQCALLSKLLRTLERENQRLEAVLAWRRSELVFWRW 182


>gi|199560438 hypothetical protein LOC283643 isoform 2 [Homo
           sapiens]
          Length = 393

 Score = 27.7 bits (60), Expect = 4.3
 Identities = 13/51 (25%), Positives = 30/51 (58%)

Query: 12  GKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRY 62
           GKLR +   L +S +E+  ++ +L++ +     ++ + L WR  ++V+ R+
Sbjct: 173 GKLRFRWRQLVSSQQEQCALLSKLLRTLERENQRLEAVLAWRRSELVFWRW 223


>gi|239757058 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 603

 Score = 26.9 bits (58), Expect = 7.3
 Identities = 17/55 (30%), Positives = 29/55 (52%), Gaps = 3/55 (5%)

Query: 70  AIEGQDNELITLELIHRYV---ELLDKYFGSVCELDIIFNFEKAYFILDEFLMGG 121
           A++ +  EL++ E I  Y+   +LL  +  SVC+   +F F   +F  +  L GG
Sbjct: 180 ALKEKQTELLSEEKIVFYLSSPQLLAYFLISVCDQLALFRFHSTHFPRNTVLRGG 234


>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
          Length = 1093

 Score = 26.9 bits (58), Expect = 7.3
 Identities = 12/23 (52%), Positives = 17/23 (73%)

Query: 132 LKAIEQADLLQEEDESPRSVLEE 154
           L + E ADLL+E+DE  R ++EE
Sbjct: 539 LNSSETADLLKEKDEQIRGLMEE 561


>gi|196114970 protein tyrosine phosphatase, non-receptor type 12
           isoform 3 [Homo sapiens]
          Length = 650

 Score = 26.6 bits (57), Expect = 9.5
 Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 96  GSVCELDIIFNFEKAYFILDEFLMGGDVQD--TSKKSVLKAIEQADLL 141
           G++C +D  +N  KA  I +EF +   +Q+  T + S ++  EQ +L+
Sbjct: 109 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELV 156


>gi|196114967 protein tyrosine phosphatase, non-receptor type 12
           isoform 2 [Homo sapiens]
          Length = 661

 Score = 26.6 bits (57), Expect = 9.5
 Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 2/48 (4%)

Query: 96  GSVCELDIIFNFEKAYFILDEFLMGGDVQD--TSKKSVLKAIEQADLL 141
           G++C +D  +N  KA  I +EF +   +Q+  T + S ++  EQ +L+
Sbjct: 120 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELV 167


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,450,717
Number of Sequences: 37866
Number of extensions: 216061
Number of successful extensions: 723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 695
Number of HSP's gapped (non-prelim): 34
length of query: 158
length of database: 18,247,518
effective HSP length: 94
effective length of query: 64
effective length of database: 14,688,114
effective search space: 940039296
effective search space used: 940039296
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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