Guide to the Human Genome
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Search of human proteins with 45545421

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
[Homo sapiens]
         (458 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [...   942   0.0  
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (...   257   2e-68
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas...   243   3e-64
gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p...   213   3e-55
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [...   211   1e-54
gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ...   187   2e-47
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ...   186   5e-47
gi|169217659 PREDICTED: similar to ectonucleotide pyrophosphatas...   176   4e-44
gi|169167316 PREDICTED: similar to ectonucleotide pyrophosphatas...   176   4e-44
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]         176   4e-44
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]          176   4e-44
gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]          162   5e-40
gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens]          162   5e-40
gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]          154   2e-37
gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens]          115   1e-25
gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens]          115   1e-25
gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens]          115   1e-25
gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo ...   107   2e-23
gi|239743501 PREDICTED: similar to hCG2042391 [Homo sapiens]          105   9e-23
gi|239750115 PREDICTED: similar to hCG2042391 [Homo sapiens]           99   6e-21
gi|38045917 phosphatidylinositol glycan anchor biosynthesis, cla...    45   1e-04
gi|23397648 phosphatidylinositol glycan anchor biosynthesis, cla...    45   1e-04
gi|157266309 arylsulfatase E precursor [Homo sapiens]                  37   0.029
gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens]         37   0.037
gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens]         37   0.037
gi|109389362 arylsulfatase J [Homo sapiens]                            35   0.19 
gi|59797060 arylsulfatase family, member I [Homo sapiens]              33   0.54 
gi|4758822 nephrin precursor [Homo sapiens]                            32   1.2  
gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precurso...    32   1.2  
gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]      32   1.2  

>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
           [Homo sapiens]
          Length = 458

 Score =  942 bits (2435), Expect = 0.0
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MRGLAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARD 60
           MRGLAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARD
Sbjct: 1   MRGLAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARD 60

Query: 61  GVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWD 120
           GVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWD
Sbjct: 61  GVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWD 120

Query: 121 NGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVM 180
           NGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVM
Sbjct: 121 NGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVM 180

Query: 181 AWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLN 240
           AWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLN
Sbjct: 181 AWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLN 240

Query: 241 LIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDAL 300
           LIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDAL
Sbjct: 241 LIITSDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDAL 300

Query: 301 KDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDM 360
           KDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDM
Sbjct: 301 KDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDM 360

Query: 361 DMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420
           DMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP
Sbjct: 361 DMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420

Query: 421 PDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA 458
           PDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA
Sbjct: 421 PDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA 458


>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
           (putative function) [Homo sapiens]
          Length = 477

 Score =  257 bits (656), Expect = 2e-68
 Identities = 159/438 (36%), Positives = 237/438 (54%), Gaps = 26/438 (5%)

Query: 27  QGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGK 86
           Q  Q K+LLVSFDGFRW+Y   V TP+   + + GV  + +T  F+T T P H+TLVTG 
Sbjct: 24  QPDQQKVLLVSFDGFRWDYLYKVPTPHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGL 83

Query: 87  YIENHGVVHN-MYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGG 145
           + ENHG+V N M+    +K     H  +   ++W+  + PIWIT QR G  +G+  +PG 
Sbjct: 84  FAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEAT-PIWITNQRAGHTSGAAMWPGT 142

Query: 146 NVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFT-EEDLDLVTLYFGEPDSTGHR 204
           +V       T          Y     +   +  ++ WFT +E ++L  LY+ +PD  GH 
Sbjct: 143 DVKIHKRFPTHYMP------YNESVSFEDRVAKIIEWFTSKEPINLGLLYWEDPDDMGHH 196

Query: 205 YGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHK 264
            GP+SP    ++  +D+ +GYL + + +  L + LNLIITSDHGMT   +    L+E  +
Sbjct: 197 LGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEER--LIELDQ 254

Query: 265 FPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANN 324
           + +   +D  + L+D  P   +LPKEG+ ++VY+AL  AHP L VYKKE  PE +HY  N
Sbjct: 255 YLD---KD-HYTLIDQSPVAAILPKEGKFDEVYEALTHAHPNLTVYKKEDVPERWHYKYN 310

Query: 325 PRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFES 384
            R+ P++  +D G+ I    +  F  G HG+DN   DM  IF A GP+FR     E   S
Sbjct: 311 SRIQPIIAVADEGWHILQNKSDDFLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNS 370

Query: 385 VHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP---PDGRPTLLPKGRSALP----- 436
             +Y L+C LL I    ++G    +  +L+  SA+P   P  + T+L  G S  P     
Sbjct: 371 TDLYPLLCHLLNITAMPHNGSFWNVQDLLN--SAMPRVVPYTQSTILLPG-SVKPAEYDQ 427

Query: 437 PSSRPLLVMGLLGTVILL 454
             S P  +   LG++I++
Sbjct: 428 EGSYPYFIGVSLGSIIVI 445


>gi|239755573 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 (putative function)
           [Homo sapiens]
          Length = 661

 Score =  243 bits (619), Expect = 3e-64
 Identities = 137/320 (42%), Positives = 178/320 (55%), Gaps = 30/320 (9%)

Query: 133 QGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVT 192
           +G +A S  Y  G   Y+G AV RS  E   H   NETE R NIDTVM  FT+ED D VT
Sbjct: 224 KGKKAASSHYSRGGAKYEGEAVKRSLVESYTHQNSNETEQRENIDTVMNCFTKEDFDFVT 283

Query: 193 LYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTV 252
           LY+ +PD+ GHR+ PE+  R+ M++Q+DRT+ YL       H      +IIT DHGM TV
Sbjct: 284 LYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYL-VGATEKHSLQSPQVIITXDHGMMTV 342

Query: 253 DKRAGDLVEFHKFPNF-TFRD-IEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVY 310
            KR    V      N+  FRD ++F+++ YG  G+ LPK G+ E +Y ALK+AHP LH+Y
Sbjct: 343 KKRPN--VNKIXLSNYIKFRDWVKFDIVGYGGFGLPLPKLGQEEALYQALKNAHPHLHIY 400

Query: 311 KKEAFPEAFHYANNPRVTPLLMYSDLGYVI-------------------------HGRIN 345
           KKE FPE FH A + RV P++MY++  Y                             RI 
Sbjct: 401 KKEEFPEHFHLAKHDRVLPIVMYANSSYRYLDSSMRTFNETRTFPTDQPDSLREQDARII 460

Query: 346 VQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGH 405
           + FN G HGFDN  MDMKTIFR  GP F+     E F S+H+Y  +C+LLG+ P+ ++G 
Sbjct: 461 MCFNKGSHGFDNVLMDMKTIFRDFGPDFKKNGLAETFNSIHIYPFVCKLLGVXPQTHNGS 520

Query: 406 LATLLPMLHTESALPPDGRP 425
           LA    ML       P   P
Sbjct: 521 LAVTQEMLVNSYDQQPASEP 540



 Score =  122 bits (305), Expect = 9e-28
 Identities = 59/127 (46%), Positives = 80/127 (62%), Gaps = 2/127 (1%)

Query: 11  ALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPA 70
           A A +  P    P   +   ++LLL+SF GFRW+ DQDVDTPN+D +A +GVKA+Y+ P 
Sbjct: 7   AAAAIACPAGRPPPPREEEHSQLLLISFQGFRWDXDQDVDTPNMDHLAGEGVKAKYLMPP 66

Query: 71  FVTMTSPCHFTLVTGK--YIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWI 128
            VTMTSP HFT + GK  ++ +H V+HNM +NT       +  T    +  DN  + +WI
Sbjct: 67  LVTMTSPFHFTAMPGKLLWVRDHXVIHNMMFNTEMLWNCSFKTTQKKTQCXDNRVLSLWI 126

Query: 129 TAQRQGL 135
           TAQRQGL
Sbjct: 127 TAQRQGL 133


>gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4
           (putative function) [Homo sapiens]
          Length = 453

 Score =  213 bits (542), Expect = 3e-55
 Identities = 131/400 (32%), Positives = 208/400 (52%), Gaps = 23/400 (5%)

Query: 12  LATLLAPGAGAPVQSQGSQN---KLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMT 68
           L  LL  G     +S  S +   KLLLVSFDGFR +Y ++ + P+L    ++GV   ++ 
Sbjct: 4   LVILLFSGLITGFRSDSSSSLPPKLLLVSFDGFRADYLKNYEFPHLQNFIKEGVLVEHVK 63

Query: 69  PAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWI 128
             F+T T P H+++VTG Y E+HG+V N  Y+  +K    +  +     +W N +VPIW+
Sbjct: 64  NVFITKTFPNHYSIVTGLYEESHGIVANSMYDAVTKKH--FSDSNDKDPFWWNEAVPIWV 121

Query: 129 TAQRQGLR-AGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEED 187
           T Q Q  R + +  +PG +V                 NY +   +   ++ +  W    +
Sbjct: 122 TNQLQENRSSAAAMWPGTDVPIHDTI------SSYFMNYNSSVSFEERLNNITMWLNNSN 175

Query: 188 --LDLVTLYFGEPDSTGHRYGPESPERREMV-RQVDRTVGYLRESIARNHLTDRLNLIIT 244
             +   TLY+ EPD++GH+YGPE  E    V +++D  +G L + +    L + LN+IIT
Sbjct: 176 PPVTFATLYWEEPDASGHKYGPEDKENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIIT 235

Query: 245 SDHGMTTVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAH 304
           SDHGMT   +    L+      + ++    + L+D  P   +LPK  R E VY+ LK+  
Sbjct: 236 SDHGMTQCSQ--DRLINLDSCIDHSY----YTLIDLSPVAAILPKINRTE-VYNKLKNCS 288

Query: 305 PKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKT 364
           P ++VY KE  P  F+Y +N R+ P+++ +D G+ I    + Q   G+HG+DN    M  
Sbjct: 289 PHMNVYLKEDIPNRFYYQHNDRIQPIILVADEGWTIVLNESSQ-KLGDHGYDNSLPSMHP 347

Query: 365 IFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDG 404
              A GP+F  G +      V +Y +MC +LG+ P  N+G
Sbjct: 348 FLAAHGPAFHKGYKHSTINIVDIYPMMCHILGLKPHPNNG 387


>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
           [Homo sapiens]
          Length = 440

 Score =  211 bits (536), Expect = 1e-54
 Identities = 138/443 (31%), Positives = 220/443 (49%), Gaps = 40/443 (9%)

Query: 8   LTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDV---DTPNLDAMARDGVKA 64
           + V L TLL   A    Q   ++ KLL+   DGFR +Y  D      P    +   GVK 
Sbjct: 1   MAVKLGTLLLALALGLAQPASARRKLLVFLLDGFRSDYISDEALESLPGFKEIVSRGVKV 60

Query: 65  RYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQR------W 118
            Y+TP F +++ P ++TL+TG++ E H ++ N  ++ T+         +G+ +      W
Sbjct: 61  DYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPTTNKSFD----IGVNKDSLMPLW 116

Query: 119 WDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDT 178
           W NGS P+W+T  +   +   +++PG  V   GV  T   +     N   +  +   +  
Sbjct: 117 W-NGSEPLWVTLTKAKRKVYMYYWPGCEVEILGVRPTYCLEY---KNVPTDINFANAVSD 172

Query: 179 VMAWFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDR 238
            +  F     DL  +Y    D  GH YGP SP+R++ ++ VD  + Y+ + I    L DR
Sbjct: 173 ALDSFKSGRADLAAIYHERIDVEGHHYGPASPQRKDALKAVDTVLKYMTKWIQERGLQDR 232

Query: 239 LNLIITSDHGMTTV---DKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEK 295
           LN+II SDHGMT +   DK    ++E +K+   +  D++ ++ D GP   L P  G+  +
Sbjct: 233 LNVIIFSDHGMTDIFWMDK----VIELNKY--ISLNDLQ-QVKDRGPVVSLWPAPGKHSE 285

Query: 296 VYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVI-HGRINVQF------ 348
           +Y+ L      + VY+KEA P  F+Y     V+PL + +D G+ I   R  + F      
Sbjct: 286 IYNKLSTVE-HMTVYEKEAIPSRFYYKKGKFVSPLTLVADEGWFITENREMLPFWMNSTG 344

Query: 349 -----NNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEAND 403
                  G HG+DN+ MDM+ IF A GP F++     P  SV VY +MC ++GI P  N+
Sbjct: 345 RREGWQRGWHGYDNELMDMRGIFLAFGPDFKSNFRAAPIRSVDVYNVMCNVVGITPLPNN 404

Query: 404 GHLATLLPMLHTESALPPDGRPT 426
           G  + ++ ML   ++  P   P+
Sbjct: 405 GSWSRVMCMLKGRASTAPPVWPS 427


>gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
           [Homo sapiens]
          Length = 875

 Score =  187 bits (474), Expect = 2e-47
 Identities = 126/398 (31%), Positives = 192/398 (48%), Gaps = 32/398 (8%)

Query: 33  LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90
           ++L S DGFR  Y    DT  PN++ +   G+ ++YM   + T T P H+T+VTG Y E+
Sbjct: 161 VILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPES 220

Query: 91  HGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQ 150
           HG++ N  Y+          +       W +G  P+W+TA  QGL+A ++F+PG  V   
Sbjct: 221 HGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQ-PMWLTAMYQGLKAATYFWPGSEVAIN 279

Query: 151 GVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFT---EEDLDLVTLYFGEPDSTGHRYGP 207
           G   +      I   Y     +   I T++ W      E     T+YF EPDS+GH  GP
Sbjct: 280 GSFPS------IYMPYNGSVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGP 333

Query: 208 ESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPN 267
            S    + ++ VD   G L E + + +L + +N+I+ +DHGM        D    +K   
Sbjct: 334 VSARVIKALQVVDHAFGMLMEGLKQRNLHNCVNIILLADHGM--------DQTYCNKMEY 385

Query: 268 FT--FRDIEFELLDYGPNGML----LPKEG---RLEKVYDALKDAHPKLHV--YKKEAFP 316
            T  F  I F  +  GP   +    +P +      E++   L    P  H   Y     P
Sbjct: 386 MTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLP 445

Query: 317 EAFHYANNPRVTPLLMYSDLGYV-IHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRA 375
           +  HYA N R+  + ++ D  ++ +  + N     G HG++N+   M+ IF A GPSF+ 
Sbjct: 446 KRLHYAKNVRIDKVHLFVDQQWLAVRSKSNTNCGGGNHGYNNEFRSMEAIFLAHGPSFKE 505

Query: 376 GLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPML 413
             EVEPFE++ VY LMC LL I P  N+G   +L  +L
Sbjct: 506 KTEVEPFENIEVYNLMCDLLRIQPAPNNGTHGSLNHLL 543


>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Homo sapiens]
          Length = 925

 Score =  186 bits (471), Expect = 5e-47
 Identities = 124/396 (31%), Positives = 185/396 (46%), Gaps = 29/396 (7%)

Query: 34  LLVSFDGFRWNYDQDVD--TPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENH 91
           LL S DGFR  Y        P +  + + G   + M P + T T P H+++VTG Y E+H
Sbjct: 213 LLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESH 272

Query: 92  GVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQG 151
           G++ N  Y+          +       W  G  PIW+TA+ QGL++G+FF+PG +V   G
Sbjct: 273 GIIDNKMYDPKMNASFSLKSKEKFNPEWYKGE-PIWVTAKYQGLKSGTFFWPGSDVEING 331

Query: 152 VAVTRSRKEGIAHNYKNETEWRANIDTVMAWFT---EEDLDLVTLYFGEPDSTGHRYGPE 208
           +         I   Y     +   I  V+ W     +E     TLY  EPDS+GH YGP 
Sbjct: 332 IF------PDIYKMYNGSVPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPV 385

Query: 209 SPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNF 268
           S E  + +++VD  VG L + +   +L   LNLI+ SDHGM     +       + + N 
Sbjct: 386 SSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKK------YIYLNK 439

Query: 269 TFRDIEFELLDYGPNGMLLPKE-------GRLEKVYDALKDAHPKLHV--YKKEAFPEAF 319
              D++   + YGP   L P +          E +   L    P  H   Y K   P+  
Sbjct: 440 YLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRL 499

Query: 320 HYANNPRVTPLLMYSDLGY--VIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGL 377
           H+A + R+ PL  Y D  +   ++        +G HG DN   +M+ +F   GP F+ G+
Sbjct: 500 HFAKSDRIEPLTFYLDPQWQLALNPSERKYCGSGFHGSDNVFSNMQALFVGYGPGFKHGI 559

Query: 378 EVEPFESVHVYELMCRLLGIVPEANDGHLATLLPML 413
           E + FE++ VY LMC LL + P  N+G   +L  +L
Sbjct: 560 EADTFENIEVYNLMCDLLNLTPAPNNGTHGSLNHLL 595


>gi|169217659 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
          Length = 542

 Score =  176 bits (446), Expect = 4e-44
 Identities = 94/200 (47%), Positives = 125/200 (62%), Gaps = 24/200 (12%)

Query: 150 QGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPES 209
           +G AV RS  E   H   NETE R NIDT+M WFT+ED D VTL + EPD+ GHR+GPE+
Sbjct: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79

Query: 210 PERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFP--- 266
             R+ M++Q+ RT+G                +IIT DHG+TT  KR       +K P   
Sbjct: 80  ENRKLMIQQIGRTIG----------------VIITRDHGVTTEKKRP----NVNKIPLSN 119

Query: 267 NFTFRD-IEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNP 325
              FRD ++F+++ YG  GM LPK G+ E +Y ALK+A+P LH+YKKE FPE FH A + 
Sbjct: 120 YIKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHD 179

Query: 326 RVTPLLMYSDLGYVIHGRIN 345
           RV P++MY++ GY I+G  N
Sbjct: 180 RVLPIVMYANSGYTINGAEN 199


>gi|169167316 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
          Length = 542

 Score =  176 bits (446), Expect = 4e-44
 Identities = 94/200 (47%), Positives = 125/200 (62%), Gaps = 24/200 (12%)

Query: 150 QGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDSTGHRYGPES 209
           +G AV RS  E   H   NETE R NIDT+M WFT+ED D VTL + EPD+ GHR+GPE+
Sbjct: 20  EGEAVKRSLVESYTHPNSNETERRENIDTIMNWFTKEDFDFVTLCYREPDNVGHRFGPEA 79

Query: 210 PERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFP--- 266
             R+ M++Q+ RT+G                +IIT DHG+TT  KR       +K P   
Sbjct: 80  ENRKLMIQQIGRTIG----------------VIITRDHGVTTEKKRP----NVNKIPLSN 119

Query: 267 NFTFRD-IEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNP 325
              FRD ++F+++ YG  GM LPK G+ E +Y ALK+A+P LH+YKKE FPE FH A + 
Sbjct: 120 YIKFRDWVKFDIVGYGGFGMPLPKSGQEEALYQALKNAYPHLHIYKKEEFPEHFHIAKHD 179

Query: 326 RVTPLLMYSDLGYVIHGRIN 345
           RV P++MY++ GY I+G  N
Sbjct: 180 RVLPIVMYANSGYTINGAEN 199


>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
          Length = 888

 Score =  176 bits (446), Expect = 4e-44
 Identities = 130/416 (31%), Positives = 197/416 (47%), Gaps = 67/416 (16%)

Query: 33  LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90
           L++ S DGFR +Y +      PN++ +   G  + YM P + T T P  +TL TG Y E+
Sbjct: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225

Query: 91  HGVVHNMYYNTTSKVKLPYHATLGIQ-------RWWDNGSVPIWITAQRQGLRAGSFFYP 143
           HG+V N  Y+        + AT  ++       RWW  G  P+WITA +QG++AG+FF+ 
Sbjct: 226 HGIVGNSMYDPV------FDATFHLRGREKFNHRWW--GGQPLWITATKQGVKAGTFFW- 276

Query: 144 GGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLD---LVTLYFGEPDS 200
                   V +   R+                I T++ W T  D +   +   Y  +PD 
Sbjct: 277 -------SVVIPHERR----------------ILTILQWLTLPDHERPSVYAFYSEQPDF 313

Query: 201 TGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLV 260
           +GH+YGP  PE    +R++D+ VG L + + +  L   +N+I   DHGM  V     D  
Sbjct: 314 SGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDV---TCDRT 370

Query: 261 EFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDA------LKDAHPKLHV--YKK 312
           EF    N+     +  L+  G  G +  K     K YD       L    P  H   Y K
Sbjct: 371 EF--LSNYLTNVDDITLVP-GTLGRIRSKFSNNAK-YDPKAIIANLTCKKPDQHFKPYLK 426

Query: 313 EAFPEAFHYANNPRVTPL-LMYSDLGYVIHGRINVQ-------FNNGEHGFDNKDMDMKT 364
           +  P+  HYANN R+  + L+     +V    ++V        F  G+HGFDNK   M+T
Sbjct: 427 QHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQT 486

Query: 365 IFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420
           +F   G +F+   +V PFE++ +Y +MC LLG+ P  N+G   +L  +L T +  P
Sbjct: 487 VFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP 542


>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
          Length = 863

 Score =  176 bits (446), Expect = 4e-44
 Identities = 130/416 (31%), Positives = 197/416 (47%), Gaps = 67/416 (16%)

Query: 33  LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90
           L++ S DGFR +Y +      PN++ +   G  + YM P + T T P  +TL TG Y E+
Sbjct: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225

Query: 91  HGVVHNMYYNTTSKVKLPYHATLGIQ-------RWWDNGSVPIWITAQRQGLRAGSFFYP 143
           HG+V N  Y+        + AT  ++       RWW  G  P+WITA +QG++AG+FF+ 
Sbjct: 226 HGIVGNSMYDPV------FDATFHLRGREKFNHRWW--GGQPLWITATKQGVKAGTFFW- 276

Query: 144 GGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLD---LVTLYFGEPDS 200
                   V +   R+                I T++ W T  D +   +   Y  +PD 
Sbjct: 277 -------SVVIPHERR----------------ILTILQWLTLPDHERPSVYAFYSEQPDF 313

Query: 201 TGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLV 260
           +GH+YGP  PE    +R++D+ VG L + + +  L   +N+I   DHGM  V     D  
Sbjct: 314 SGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDV---TCDRT 370

Query: 261 EFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDA------LKDAHPKLHV--YKK 312
           EF    N+     +  L+  G  G +  K     K YD       L    P  H   Y K
Sbjct: 371 EF--LSNYLTNVDDITLVP-GTLGRIRSKFSNNAK-YDPKAIIANLTCKKPDQHFKPYLK 426

Query: 313 EAFPEAFHYANNPRVTPL-LMYSDLGYVIHGRINVQ-------FNNGEHGFDNKDMDMKT 364
           +  P+  HYANN R+  + L+     +V    ++V        F  G+HGFDNK   M+T
Sbjct: 427 QHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQT 486

Query: 365 IFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420
           +F   G +F+   +V PFE++ +Y +MC LLG+ P  N+G   +L  +L T +  P
Sbjct: 487 VFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP 542


>gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]
          Length = 167

 Score =  162 bits (411), Expect = 5e-40
 Identities = 80/92 (86%), Positives = 83/92 (90%)

Query: 1  MRGLAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARD 60
          MRG  VLLTVAL TLLAP AGAPVQSQGS+NKLLLVSFD FRWNY+QDVDTPNLDAMARD
Sbjct: 1  MRGPTVLLTVALPTLLAPRAGAPVQSQGSRNKLLLVSFDSFRWNYEQDVDTPNLDAMARD 60

Query: 61 GVKARYMTPAFVTMTSPCHFTLVTGKYIENHG 92
          GVKARYMTPAFVTMTSPCHFTLVTG+Y    G
Sbjct: 61 GVKARYMTPAFVTMTSPCHFTLVTGEYCPRMG 92


>gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens]
          Length = 98

 Score =  162 bits (411), Expect = 5e-40
 Identities = 80/92 (86%), Positives = 83/92 (90%)

Query: 1  MRGLAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARD 60
          MRG  VLLTVAL TLLAP AGAPVQSQGS+NKLLLVSFD FRWNY+QDVDTPNLDAMARD
Sbjct: 1  MRGPTVLLTVALPTLLAPRAGAPVQSQGSRNKLLLVSFDSFRWNYEQDVDTPNLDAMARD 60

Query: 61 GVKARYMTPAFVTMTSPCHFTLVTGKYIENHG 92
          GVKARYMTPAFVTMTSPCHFTLVTG+Y    G
Sbjct: 61 GVKARYMTPAFVTMTSPCHFTLVTGEYCPRMG 92


>gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
          Length = 915

 Score =  154 bits (388), Expect = 2e-37
 Identities = 132/468 (28%), Positives = 202/468 (43%), Gaps = 119/468 (25%)

Query: 33  LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90
           L++ S DGFR +Y +      PN++ +   G  + YM P + T T P  +TL TG Y E+
Sbjct: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225

Query: 91  HGVVHNMYYNTTSKVKLPYHATLGIQ-------RWWDNGSVPIWITAQRQGLRAGSFFYP 143
           HG+V N  Y+        + AT  ++       RWW  G  P+WITA +QG++AG+FF+ 
Sbjct: 226 HGIVGNSMYDPV------FDATFHLRGREKFNHRWW--GGQPLWITATKQGVKAGTFFW- 276

Query: 144 GGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLD---LVTLYFGEPDS 200
                   V +   R+                I T++ W T  D +   +   Y  +PD 
Sbjct: 277 -------SVVIPHERR----------------ILTILQWLTLPDHERPSVYAFYSEQPDF 313

Query: 201 TGHRYGPESPE----------------------------------RREM----------- 215
           +GH+YGP  PE                                  RR++           
Sbjct: 314 SGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRRKIHRMDHYAAETR 373

Query: 216 -------VRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLVEFHKFPNF 268
                  +R++D+ VG L + + +  L   +N+I   DHGM  V     D  EF    N+
Sbjct: 374 QDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDV---TCDRTEF--LSNY 428

Query: 269 TFRDIEFELLDYGPNGMLLPKEGRLEKVYDA------LKDAHPKLHV--YKKEAFPEAFH 320
              +++   L  G  G +  K     K YD       L    P  H   Y K+  P+  H
Sbjct: 429 -LTNVDDITLVPGTLGRIRSKFSNNAK-YDPKAIIANLTCKKPDQHFKPYLKQHLPKRLH 486

Query: 321 YANNPRVTPL-LMYSDLGYVIHGRINVQ-------FNNGEHGFDNKDMDMKTIFRAVGPS 372
           YANN R+  + L+     +V    ++V        F  G+HGFDNK   M+T+F   G +
Sbjct: 487 YANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGST 546

Query: 373 FRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420
           F+   +V PFE++ +Y +MC LLG+ P  N+G   +L  +L T +  P
Sbjct: 547 FKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP 594


>gi|169209673 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score =  115 bits (287), Expect = 1e-25
 Identities = 53/94 (56%), Positives = 64/94 (68%)

Query: 133 QGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVT 192
           QG +A S  Y  G   Y G AV RS  E   H   NETEWR NIDTVM WFT+ED D VT
Sbjct: 14  QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFDFVT 73

Query: 193 LYFGEPDSTGHRYGPESPERREMVRQVDRTVGYL 226
           L + EPD+ GHR+GPE+  R+ M++Q+DRT+GYL
Sbjct: 74  LCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYL 107


>gi|169210658 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score =  115 bits (287), Expect = 1e-25
 Identities = 53/94 (56%), Positives = 64/94 (68%)

Query: 133 QGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVT 192
           QG +A S  Y  G   Y G AV RS  E   H   NETEWR NIDTVM WFT+ED D VT
Sbjct: 14  QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFDFVT 73

Query: 193 LYFGEPDSTGHRYGPESPERREMVRQVDRTVGYL 226
           L + EPD+ GHR+GPE+  R+ M++Q+DRT+GYL
Sbjct: 74  LCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYL 107


>gi|169210188 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 129

 Score =  115 bits (287), Expect = 1e-25
 Identities = 53/94 (56%), Positives = 64/94 (68%)

Query: 133 QGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVT 192
           QG +A S  Y  G   Y G AV RS  E   H   NETEWR NIDTVM WFT+ED D VT
Sbjct: 14  QGNKAASSHYSRGGAKYDGEAVKRSLVESYTHPNSNETEWRENIDTVMNWFTKEDFDFVT 73

Query: 193 LYFGEPDSTGHRYGPESPERREMVRQVDRTVGYL 226
           L + EPD+ GHR+GPE+  R+ M++Q+DRT+GYL
Sbjct: 74  LCYREPDNVGHRFGPEAENRKLMIQQIDRTIGYL 107


>gi|239743493 PREDICTED: hypothetical protein XP_002342862 [Homo
           sapiens]
          Length = 169

 Score =  107 bits (268), Expect = 2e-23
 Identities = 50/93 (53%), Positives = 64/93 (68%)

Query: 134 GLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTL 193
           G RA SF Y  G   Y+G AV  S  +   H   NETE + NIDTVM WFT+ED D VTL
Sbjct: 55  GNRAASFHYSRGGAKYEGEAVKWSLVDSYTHPSSNETERKENIDTVMNWFTKEDFDFVTL 114

Query: 194 YFGEPDSTGHRYGPESPERREMVRQVDRTVGYL 226
            + EPD+ GHR+GPE+ +R+ M++Q+DRT+GYL
Sbjct: 115 CYREPDNVGHRFGPEAEKRKLMIQQIDRTIGYL 147


>gi|239743501 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 169

 Score =  105 bits (262), Expect = 9e-23
 Identities = 49/93 (52%), Positives = 63/93 (67%)

Query: 134 GLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTL 193
           G RA SF Y  G   Y+G AV  S  +   H   NETE + NID VM WFT+ED D VTL
Sbjct: 55  GNRAASFHYSRGGAKYEGEAVKWSLVDSYTHPSSNETERKENIDIVMNWFTKEDFDFVTL 114

Query: 194 YFGEPDSTGHRYGPESPERREMVRQVDRTVGYL 226
            + EPD+ GHR+GPE+ +R+ M++Q+DRT+GYL
Sbjct: 115 CYREPDNVGHRFGPEAEKRKLMIQQIDRTIGYL 147


>gi|239750115 PREDICTED: similar to hCG2042391 [Homo sapiens]
          Length = 149

 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 47/91 (51%), Positives = 60/91 (65%)

Query: 136 RAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYF 195
           +A S  Y  G   Y+G AV R   E   H   NETE R NIDTVM WFT+ED D+VTL +
Sbjct: 37  KAASSHYSRGGAKYEGEAVKRCLVESYTHPNSNETERRENIDTVMNWFTKEDFDIVTLCY 96

Query: 196 GEPDSTGHRYGPESPERREMVRQVDRTVGYL 226
            EPD+  HR+ PE+  R+ M++Q+DRT+GYL
Sbjct: 97  REPDNVRHRFRPEAENRKLMIQQLDRTIGYL 127


>gi|38045917 phosphatidylinositol glycan anchor biosynthesis, class
           O isoform 2 [Homo sapiens]
          Length = 672

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%)

Query: 189 DLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHG 248
           D++  +F   D  GH++GP  PE  + + Q+D+ +  L E +  + L     L++  DHG
Sbjct: 225 DVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHG 279

Query: 249 MTTVDKRAGD 258
           MTT     GD
Sbjct: 280 MTTNGDHGGD 289


>gi|23397648 phosphatidylinositol glycan anchor biosynthesis, class
           O isoform 1 [Homo sapiens]
          Length = 1089

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%)

Query: 189 DLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHG 248
           D++  +F   D  GH++GP  PE  + + Q+D+ +  L E +  + L     L++  DHG
Sbjct: 225 DVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHG 279

Query: 249 MTTVDKRAGD 258
           MTT     GD
Sbjct: 280 MTTNGDHGGD 289


>gi|157266309 arylsulfatase E precursor [Homo sapiens]
          Length = 589

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 34/100 (34%), Positives = 51/100 (51%), Gaps = 12/100 (12%)

Query: 4   LAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFD---GFRWNYDQD-VDTPNLDAMAR 59
           LAVLL+      LAP A + + S    N LLL++ D   G    Y  + + TPN+D +A 
Sbjct: 19  LAVLLS------LAPSASSDI-SASRPNILLLMADDLGIGDIGCYGNNTMRTPNIDRLAE 71

Query: 60  DGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYY 99
           DGVK      A  ++ +P     +TG+Y    G+V ++ Y
Sbjct: 72  DGVKLTQHISA-ASLCTPSRAAFLTGRYPVRSGMVSSIGY 110


>gi|38569407 arylsulfatase B isoform 2 precursor [Homo sapiens]
          Length = 413

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 34/104 (32%), Positives = 47/104 (45%), Gaps = 16/104 (15%)

Query: 4   LAVLLTVALATLLAP---GAGAPVQSQGSQNKLLLVSFDGFRWN----YDQDVDTPNLDA 56
           L V+L + L  LLAP   GAGA          L+ +  D   WN    +   + TP+LDA
Sbjct: 20  LPVVLPLLLLLLLAPPGSGAGA-----SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDA 74

Query: 57  MARDGVKA-RYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYY 99
           +A  GV    Y T    T   P    L+TG+Y    G+ H + +
Sbjct: 75  LAAGGVLLDNYYTQPLCT---PSRSQLLTGRYQIRTGLQHQIIW 115


>gi|38569405 arylsulfatase B isoform 1 precursor [Homo sapiens]
          Length = 533

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 34/104 (32%), Positives = 47/104 (45%), Gaps = 16/104 (15%)

Query: 4   LAVLLTVALATLLAP---GAGAPVQSQGSQNKLLLVSFDGFRWN----YDQDVDTPNLDA 56
           L V+L + L  LLAP   GAGA          L+ +  D   WN    +   + TP+LDA
Sbjct: 20  LPVVLPLLLLLLLAPPGSGAGA-----SRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDA 74

Query: 57  MARDGVKA-RYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYY 99
           +A  GV    Y T    T   P    L+TG+Y    G+ H + +
Sbjct: 75  LAAGGVLLDNYYTQPLCT---PSRSQLLTGRYQIRTGLQHQIIW 115


>gi|109389362 arylsulfatase J [Homo sapiens]
          Length = 599

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 10/81 (12%)

Query: 23  PVQSQGSQNKLLLVSFD--GFR--WNYDQDVDTPNLDAMARDGVKAR--YMTPAFVTMTS 76
           P  +  SQ  L+ +  D  GFR    +  ++ TP LD +A +GVK    Y+ P    + +
Sbjct: 68  PSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQP----ICT 123

Query: 77  PCHFTLVTGKYIENHGVVHNM 97
           P     +TGKY  + G+ H++
Sbjct: 124 PSRSQFITGKYQIHTGLQHSI 144


>gi|59797060 arylsulfatase family, member I [Homo sapiens]
          Length = 569

 Score = 33.1 bits (74), Expect = 0.54
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 6/55 (10%)

Query: 45  YDQDVDTPNLDAMARDGVKAR--YMTPAFVTMTSPCHFTLVTGKYIENHGVVHNM 97
           +  D++TP LD +A  GVK    Y+ P    + +P    L+TG+Y  + G+ H++
Sbjct: 65  HGSDIETPTLDRLAAKGVKLENYYIQP----ICTPSRSQLLTGRYQIHTGLQHSI 115


>gi|4758822 nephrin precursor [Homo sapiens]
          Length = 1241

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 28/81 (34%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 379  VEPFESVHVYELMCRLLGIVPEANDG-HLATLLPMLHTESALPPDGRPTLLPKGRSALPP 437
            ++P     V+ L    LG    A+ G  L    P LH  S  P D  PT  P G S LP 
Sbjct: 1003 LQPSTRYRVWLLASNALGDSGLADKGTQLPITTPGLHQPSGEPEDQLPTEPPSGPSGLP- 1061

Query: 438  SSRPLLVMGLLGTVILLSEVA 458
                L V+  LG ++LLS  +
Sbjct: 1062 ---LLPVLFALGGLLLLSNAS 1079


>gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precursor
           [Homo sapiens]
          Length = 522

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 24/112 (21%)

Query: 6   VLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNY-----DQDVDTPNLDAMARD 60
           +LL ++ A + A GA  P         +LL+  D   W       +   +TPNLD MA +
Sbjct: 13  LLLVLSAAGMGASGAPQPPN-------ILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAE 65

Query: 61  GVKARYMTPAFVT---MTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPY 109
           G+    + P F +   + SP    L+TG+       + N +Y T +  +  Y
Sbjct: 66  GL----LFPNFYSANPLCSPSRAALLTGRL-----PIRNGFYTTNAHARNAY 108


>gi|29294655 melanoma antigen family C, 3 isoform 2 [Homo sapiens]
          Length = 346

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 15/42 (35%), Positives = 21/42 (50%)

Query: 398 VPEANDGHLATLLPMLHTESALPPDGRPTLLPKGRSALPPSS 439
           VPE  D   A + P+  +   +PP G P + P+G    PP S
Sbjct: 75  VPEDEDMPAAGMPPLPQSPPEIPPQGPPKISPQGPPQSPPQS 116


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,202,528
Number of Sequences: 37866
Number of extensions: 842059
Number of successful extensions: 2039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 1883
Number of HSP's gapped (non-prelim): 134
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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