Guide to the Human Genome
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Search of human proteins with 45505135

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45505135 phospholipase A2, group XIIB [Homo sapiens]
         (195 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45505135 phospholipase A2, group XIIB [Homo sapiens]               419   e-118
gi|21361944 phospholipase A2, group XIIA [Homo sapiens]               173   7e-44
gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]             30   1.00 
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]        30   1.7  
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]        30   1.7  
gi|40806175 diacylglycerol kinase, theta [Homo sapiens]                29   2.2  
gi|21704279 jagged 2 isoform b precursor [Homo sapiens]                29   2.9  
gi|21704277 jagged 2 isoform a precursor [Homo sapiens]                29   2.9  
gi|95113666 resistance to inhibitors of cholinesterase 8 homolog...    29   2.9  
gi|16936522 wingless-type MMTV integration site family, member 1...    28   3.8  
gi|31791016 keratin associated protein 21-2 [Homo sapiens]             28   3.8  
gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo s...    28   4.9  
gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo s...    28   4.9  
gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo sa...    28   4.9  
gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo s...    28   4.9  
gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo sap...    28   4.9  
gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo sa...    28   4.9  
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 28   6.5  
gi|4504151 granulin precursor [Homo sapiens]                           27   8.4  
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]            27   8.4  
gi|23397681 egf-like module containing, mucin-like, hormone rece...    27   8.4  
gi|23397689 egf-like module containing, mucin-like, hormone rece...    27   8.4  

>gi|45505135 phospholipase A2, group XIIB [Homo sapiens]
          Length = 195

 Score =  419 bits (1077), Expect = e-118
 Identities = 195/195 (100%), Positives = 195/195 (100%)

Query: 1   MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGK 60
           MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGK
Sbjct: 1   MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGK 60

Query: 61  NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD 120
           NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD
Sbjct: 61  NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD 120

Query: 121 TCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNS 180
           TCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNS
Sbjct: 121 TCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNS 180

Query: 181 QRAACICAEEEKEEL 195
           QRAACICAEEEKEEL
Sbjct: 181 QRAACICAEEEKEEL 195


>gi|21361944 phospholipase A2, group XIIA [Homo sapiens]
          Length = 189

 Score =  173 bits (439), Expect = 7e-44
 Identities = 77/166 (46%), Positives = 117/166 (70%), Gaps = 7/166 (4%)

Query: 32  SDWG--LRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCG 89
           +DW   L+ +R     +++Y ++ L+LLGG++G+CQY+C  G  P PR GYKP  PNGCG
Sbjct: 29  TDWRATLKTIRNGVHKIDTYLNAALDLLGGEDGLCQYKCSDGSKPFPRYGYKPSPPNGCG 88

Query: 90  SYFLGLKVPESMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLG 149
           S   G+     +++GIP++TKCCNQ D CY+TCG +K  CD +F++CL  IC D++++LG
Sbjct: 89  SPLFGVH----LNIGIPSLTKCCNQHDRCYETCGKSKNDCDEEFQYCLSKICRDVQKTLG 144

Query: 150 FVSKVEAACDSLVDTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL 195
               V+ AC++ V+ +F++V  LGC+P+++SQRAAC C  EEK +L
Sbjct: 145 LTQHVQ-ACETTVELLFDSVIHLGCKPYLDSQRAACRCHYEEKTDL 189


>gi|167830411 natriuretic peptide receptor 1 [Homo sapiens]
          Length = 1061

 Score = 30.4 bits (67), Expect = 1.00
 Identities = 17/69 (24%), Positives = 31/69 (44%)

Query: 17  GLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMP 76
           G  + D+S D E  +S W +    G+F  V +Y  +  EL+        +   Y    +P
Sbjct: 394 GYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIP 453

Query: 77  RPGYKPQEP 85
           + G+  ++P
Sbjct: 454 KCGFDNEDP 462


>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
          Length = 1164

 Score = 29.6 bits (65), Expect = 1.7
 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 8/55 (14%)

Query: 94  GLKVPES-MDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWC---LHSICSDL 144
           G+ +P   ++  +P   KC     VC  TCG+     D K  WC   +H+ C DL
Sbjct: 243 GVAMPHQWLEGNLPVSAKCA----VCDKTCGSVLRLQDWKCLWCKTMVHTACKDL 293


>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
          Length = 1220

 Score = 29.6 bits (65), Expect = 1.7
 Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 8/55 (14%)

Query: 94  GLKVPES-MDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWC---LHSICSDL 144
           G+ +P   ++  +P   KC     VC  TCG+     D K  WC   +H+ C DL
Sbjct: 243 GVAMPHQWLEGNLPVSAKCA----VCDKTCGSVLRLQDWKCLWCKTMVHTACKDL 293


>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
          Length = 942

 Score = 29.3 bits (64), Expect = 2.2
 Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 7/41 (17%)

Query: 105 IPAMTKCCNQLDVCYDTCGANKYRCDAKFRWC---LHSICS 142
           +P+  +C    +VC  TCG++      +  WC    HS+CS
Sbjct: 191 LPSGARC----EVCRKTCGSSDVLAGVRCEWCGVQAHSLCS 227


>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
          Length = 1200

 Score = 28.9 bits (63), Expect = 2.9
 Identities = 23/78 (29%), Positives = 30/78 (38%), Gaps = 6/78 (7%)

Query: 88  CGSYFLGLKVPESMD--LGIPAMT--KCCNQLDV--CYDTCGANKYRCDAKFRWCLHSIC 141
           C S F G    E++D  LG P      C +++D   C+   G     CD     CL   C
Sbjct: 586 CDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPC 645

Query: 142 SDLKRSLGFVSKVEAACD 159
               R    V+    ACD
Sbjct: 646 HSRGRCYDLVNDFYCACD 663


>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
          Length = 1238

 Score = 28.9 bits (63), Expect = 2.9
 Identities = 23/78 (29%), Positives = 30/78 (38%), Gaps = 6/78 (7%)

Query: 88  CGSYFLGLKVPESMD--LGIPAMT--KCCNQLDV--CYDTCGANKYRCDAKFRWCLHSIC 141
           C S F G    E++D  LG P      C +++D   C+   G     CD     CL   C
Sbjct: 624 CDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPC 683

Query: 142 SDLKRSLGFVSKVEAACD 159
               R    V+    ACD
Sbjct: 684 HSRGRCYDLVNDFYCACD 701


>gi|95113666 resistance to inhibitors of cholinesterase 8 homolog B
           [Homo sapiens]
          Length = 520

 Score = 28.9 bits (63), Expect = 2.9
 Identities = 16/77 (20%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 96  KVPESMDLGIPAMTKCCNQLDVCYDTCGANKYRC-DAKFRWCLHSICSDLKRSLGFVSKV 154
           ++ + + L +    K CN L  C D    N  +C D +  + L  + +D++  L +  + 
Sbjct: 129 QMAQQLSLELNLAAKLCNLLRKCKDRKFINDIKCFDLRLLFLLSLLHTDIRSQLRYELQG 188

Query: 155 EAACDSLVDTVFNTVWT 171
                 ++++ F+  WT
Sbjct: 189 LPLLTQILESAFSIKWT 205


>gi|16936522 wingless-type MMTV integration site family, member 10B
           precursor [Homo sapiens]
          Length = 389

 Score = 28.5 bits (62), Expect = 3.8
 Identities = 21/87 (24%), Positives = 35/87 (40%), Gaps = 20/87 (22%)

Query: 77  RPGYKPQEPNGCGSYFLGLKVPESMD----LGIPAMT-KCCNQLDVCYDTCGA------- 124
           +P  +P+  +G   YF   K P+  +    +G P    + CN+     D CG+       
Sbjct: 296 QPRLRPRRLSGELVYFE--KSPDFCERDPTMGSPGTRGRACNKTSRLLDGCGSLCCGRGH 353

Query: 125 ------NKYRCDAKFRWCLHSICSDLK 145
                    RC  +F WC + +C + K
Sbjct: 354 NVLRQTRVERCHCRFHWCCYVLCDECK 380


>gi|31791016 keratin associated protein 21-2 [Homo sapiens]
          Length = 83

 Score = 28.5 bits (62), Expect = 3.8
 Identities = 18/64 (28%), Positives = 22/64 (34%), Gaps = 7/64 (10%)

Query: 64  CQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYDTCG 123
           C Y C YG       GY      GCG    G         G    + CC    +CY  C 
Sbjct: 27  CGYGCGYGSGCRYGSGY----GTGCG---YGCGYGSGCGYGCGYSSSCCGYRPLCYRRCY 79

Query: 124 ANKY 127
           ++ Y
Sbjct: 80  SSCY 83


>gi|223468672 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 25  PDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQE 84
           P+ E S S +G   L G+    N +FD    L+  KNG       +  A  P  G+  + 
Sbjct: 430 PEDEASLSLYGKALLHGN--CYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEF 487

Query: 85  PNGCGSYFLG 94
             G  S+ LG
Sbjct: 488 VLGTDSFHLG 497


>gi|223468670 carnitine palmitoyltransferase 1B isoform c [Homo
           sapiens]
          Length = 738

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 25  PDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQE 84
           P+ E S S +G   L G+    N +FD    L+  KNG       +  A  P  G+  + 
Sbjct: 396 PEDEASLSLYGKALLHGN--CYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEF 453

Query: 85  PNGCGSYFLG 94
             G  S+ LG
Sbjct: 454 VLGTDSFHLG 463


>gi|23238254 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 25  PDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQE 84
           P+ E S S +G   L G+    N +FD    L+  KNG       +  A  P  G+  + 
Sbjct: 430 PEDEASLSLYGKALLHGN--CYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEF 487

Query: 85  PNGCGSYFLG 94
             G  S+ LG
Sbjct: 488 VLGTDSFHLG 497


>gi|223468678 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 25  PDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQE 84
           P+ E S S +G   L G+    N +FD    L+  KNG       +  A  P  G+  + 
Sbjct: 430 PEDEASLSLYGKALLHGN--CYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEF 487

Query: 85  PNGCGSYFLG 94
             G  S+ LG
Sbjct: 488 VLGTDSFHLG 497


>gi|4758050 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 25  PDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQE 84
           P+ E S S +G   L G+    N +FD    L+  KNG       +  A  P  G+  + 
Sbjct: 430 PEDEASLSLYGKALLHGN--CYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEF 487

Query: 85  PNGCGSYFLG 94
             G  S+ LG
Sbjct: 488 VLGTDSFHLG 497


>gi|23238256 carnitine palmitoyltransferase 1B isoform a [Homo
           sapiens]
          Length = 772

 Score = 28.1 bits (61), Expect = 4.9
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 25  PDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQE 84
           P+ E S S +G   L G+    N +FD    L+  KNG       +  A  P  G+  + 
Sbjct: 430 PEDEASLSLYGKALLHGN--CYNRWFDKSFTLISFKNGQLGLNAEHAWADAPIIGHLWEF 487

Query: 85  PNGCGSYFLG 94
             G  S+ LG
Sbjct: 488 VLGTDSFHLG 497


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 10/34 (29%), Positives = 20/34 (58%)

Query: 113 NQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKR 146
           +Q  VC+++CG+ +   D +  WC  ++  D +R
Sbjct: 410 SQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRR 443


>gi|4504151 granulin precursor [Homo sapiens]
          Length = 593

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 100 SMDLGIPAMTKCCN----QLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVE 155
           ++  G+ A T+C +     +  C D  GA+   C    R  L    + L R LG   +V+
Sbjct: 9   ALTAGLVAGTRCPDGQFCPVACCLDPGGASYSCC----RPLLDKWPTTLSRHLGGPCQVD 64

Query: 156 AACDSLVDTVFNTVWTLGCRPF 177
           A C +    +F    T  C PF
Sbjct: 65  AHCSAGHSCIFTVSGTSSCCPF 86


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 10/69 (14%)

Query: 61  NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD 120
           N V  Y+CR      P PG  P  PN          V E +D       +C +   VC++
Sbjct: 179 NNVGSYQCRCRPGWQPIPG-SPNGPNNT--------VCEDVDECSSGQHQC-DSSTVCFN 228

Query: 121 TCGANKYRC 129
           T G+   RC
Sbjct: 229 TVGSYSCRC 237


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 10/69 (14%)

Query: 61  NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD 120
           N V  Y+CR      P PG  P  PN          V E +D       +C +   VC++
Sbjct: 182 NNVGSYQCRCRPGWQPIPG-SPNGPNNT--------VCEDVDECSSGQHQC-DSSTVCFN 231

Query: 121 TCGANKYRC 129
           T G+   RC
Sbjct: 232 TVGSYSCRC 240


>gi|23397689 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform e [Homo sapiens]
          Length = 812

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 10/69 (14%)

Query: 61  NGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYD 120
           N V  Y+CR      P PG  P  PN          V E +D       +C +   VC++
Sbjct: 182 NNVGSYQCRCRPGWQPIPG-SPNGPNNT--------VCEDVDECSSGQHQC-DSSTVCFN 231

Query: 121 TCGANKYRC 129
           T G+   RC
Sbjct: 232 TVGSYSCRC 240


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,664,668
Number of Sequences: 37866
Number of extensions: 408841
Number of successful extensions: 958
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 951
Number of HSP's gapped (non-prelim): 22
length of query: 195
length of database: 18,247,518
effective HSP length: 97
effective length of query: 98
effective length of database: 14,574,516
effective search space: 1428302568
effective search space used: 1428302568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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