Search of human proteins with 45269149

Search of human proteins with 45269149

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45269149 quinolinate phosphoribosyltransferase [Homo
sapiens]
         (297 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45269149 quinolinate phosphoribosyltransferase [Homo sapiens]      587   e-168
gi|122937500 unc-119 homolog B [Homo sapiens]                          33   0.39 
gi|38093659 transmembrane protein 173 [Homo sapiens]                   32   0.67 
gi|239756319 PREDICTED: hypothetical protein [Homo sapiens]            30   3.3  
gi|239750846 PREDICTED: hypothetical protein [Homo sapiens]            30   3.3  
gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo ...    30   3.3  
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    29   4.4  
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]          29   5.7  
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]          29   5.7  
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol...    29   5.7  
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    29   5.7  
gi|32469509 zinc finger and BTB domain containing 12 [Homo sapiens]    29   5.7  
gi|187960098 medium-chain acyl-CoA dehydrogenase isoform b precu...    28   7.4  
gi|4557231 medium-chain acyl-CoA dehydrogenase isoform a precurs...    28   7.4  
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...    28   7.4  
gi|62988336 hypothetical protein LOC441168 [Homo sapiens]              28   7.4  
gi|219879828 rcRPE protein [Homo sapiens]                              28   9.7  
gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo ...    28   9.7  

>gi|45269149 quinolinate phosphoribosyltransferase [Homo sapiens]
          Length = 297

 Score =  587 bits (1513), Expect = e-168
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60
           MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF
Sbjct: 1   MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQAALWAKSPGVLAGQPFF 60

Query: 61  DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120
           DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA
Sbjct: 61  DAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAA 120

Query: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180
           AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG
Sbjct: 121 AVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGG 180

Query: 181 VEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240
           VEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF
Sbjct: 181 VEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQF 240

Query: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH 297
           PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH
Sbjct: 241 PSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQAAPALDFSLKLFAKEVAPVPKIH 297


>gi|122937500 unc-119 homolog B [Homo sapiens]
          Length = 251

 Score = 32.7 bits (73), Expect = 0.39
 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 9/73 (12%)

Query: 157 AASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFALKVEVECSSLQEAVQAAEAGA 216
           AA+     GGLV  K+    A GGV   ++A RQA   A           + V AA    
Sbjct: 10  AAASAAGPGGLVAGKEEKKKAGGGVLNRLKARRQAPHHA---------ADDGVGAAVTEQ 60

Query: 217 DLVLLDNFKPEEL 229
           +L+ LD  +PE +
Sbjct: 61  ELLALDTIRPEHV 73


>gi|38093659 transmembrane protein 173 [Homo sapiens]
          Length = 379

 Score = 32.0 bits (71), Expect = 0.67
 Identities = 50/188 (26%), Positives = 73/188 (38%), Gaps = 27/188 (14%)

Query: 98  LLGERVALNTLARCSGIASAAAAAV------EAARGAGWTGHVAGTRKTTPGFR-----L 146
           LLG   ALN L    G+A A  +AV        A G  W+ ++   R   P  +      
Sbjct: 123 LLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILPELQARIRTY 182

Query: 147 VEKYGLLVGGAASHR-YDLGGL-VMVKDNHVVAAGGVEKAVRAARQAADFA-LKVEVECS 203
            + Y  L+ GA S R Y L  L   V DN  +A   +    +  +Q  D A +K  V  +
Sbjct: 183 NQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSN 242

Query: 204 SLQEAVQAAEAGADLVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQ---FC 260
           S+ E ++  +     VL            AT L+  F       +G    D L Q   FC
Sbjct: 243 SIYELLENGQRAGTCVL----------EYATPLQTLFAMSQYSQAGFSREDRLEQAKLFC 292

Query: 261 GPHIDVIS 268
               D+++
Sbjct: 293 RTLEDILA 300


>gi|239756319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 463

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 7/59 (11%)

Query: 91  RGPAHCLLLGE-------RVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTP 142
           RGPA C  LG        R+  +  AR   + + +     AA G+GWT    G   + P
Sbjct: 372 RGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTRREPGLLSSAP 430


>gi|239750846 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 463

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 7/59 (11%)

Query: 91  RGPAHCLLLGE-------RVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTP 142
           RGPA C  LG        R+  +  AR   + + +     AA G+GWT    G   + P
Sbjct: 372 RGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTRREPGLLSSAP 430


>gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo
           sapiens]
          Length = 463

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 18/59 (30%), Positives = 25/59 (42%), Gaps = 7/59 (11%)

Query: 91  RGPAHCLLLGE-------RVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTP 142
           RGPA C  LG        R+  +  AR   + + +     AA G+GWT    G   + P
Sbjct: 372 RGPADCSDLGRGCFKLRVRIREDAAARRFSLGAHSTRTPRAASGSGWTRREPGLLSSAP 430


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 111 CSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEK 149
           C G A+AAAAAV      G  G   G R+ + G  +V+K
Sbjct: 6   CVGRAAAAAAAVAVPLAGGQEGSPGGGRRGSRGTTMVKK 44


>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
          Length = 508

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 4   EGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPS 42
           +GL  + P V +A   +SW +   PGL  A  V  AG S
Sbjct: 188 DGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGAS 226


>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
          Length = 490

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 15/39 (38%), Positives = 20/39 (51%)

Query: 4   EGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPS 42
           +GL  + P V +A   +SW +   PGL  A  V  AG S
Sbjct: 170 DGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGAS 208


>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1b
           [Homo sapiens]
          Length = 867

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 2/55 (3%)

Query: 83  PVARVAEVR--GPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVA 135
           P A VAEVR  GPA   LL  RVA     R   + +   AA  A         VA
Sbjct: 15  PTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSSGASQSRVA 69


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 2/55 (3%)

Query: 83  PVARVAEVR--GPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVA 135
           P A VAEVR  GPA   LL  RVA     R   + +   AA  A         VA
Sbjct: 15  PTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSSGASQSRVA 69


>gi|32469509 zinc finger and BTB domain containing 12 [Homo sapiens]
          Length = 459

 Score = 28.9 bits (63), Expect = 5.7
 Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 76  PEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIASAAAAAVEAARGAGWTGHVA 135
           P+G      +   +  G    L+ G R ++      SG+  AAA A+ AARGAG +    
Sbjct: 259 PQGVVKACYSLSEDAEGEGLLLIPGGRASVGAT---SGLVEAAAVAM-AARGAGGSLGAG 314

Query: 136 GTRKTTPG 143
           G+R   PG
Sbjct: 315 GSRGPLPG 322


>gi|187960098 medium-chain acyl-CoA dehydrogenase isoform b
           precursor [Homo sapiens]
          Length = 425

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 147 VEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFALK 197
           V K  +L+G  A  +  +G     K   VVAAG V  A RA  +A  +AL+
Sbjct: 261 VPKENVLIGDGAGFKVAMGAFD--KTRPVVAAGAVGLAQRALDEATKYALE 309


>gi|4557231 medium-chain acyl-CoA dehydrogenase isoform a precursor
           [Homo sapiens]
          Length = 421

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 147 VEKYGLLVGGAASHRYDLGGLVMVKDNHVVAAGGVEKAVRAARQAADFALK 197
           V K  +L+G  A  +  +G     K   VVAAG V  A RA  +A  +AL+
Sbjct: 257 VPKENVLIGDGAGFKVAMGAFD--KTRPVVAAGAVGLAQRALDEATKYALE 305


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo
            sapiens]
          Length = 2564

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 15/35 (42%), Positives = 19/35 (54%)

Query: 179  GGVEKAVRAARQAADFALKVEVECSSLQEAVQAAE 213
            G VE    A +Q  DF   +E+    +Q AVQAAE
Sbjct: 1229 GTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAE 1263


>gi|62988336 hypothetical protein LOC441168 [Homo sapiens]
          Length = 315

 Score = 28.5 bits (62), Expect = 7.4
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 7/70 (10%)

Query: 56  GQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGERVALNTLARCSGIA 115
           G+  F A+  Q  C  +W LP G   + V  +A         LLG  ++  T    +G  
Sbjct: 30  GERIFSAVAFQCPCSAAWNLPYGLVFLLVPALA-------LFLLGYVLSARTWRLLTGCC 82

Query: 116 SAAAAAVEAA 125
           S+A A+  +A
Sbjct: 83  SSARASCGSA 92


>gi|219879828 rcRPE protein [Homo sapiens]
          Length = 228

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 11/30 (36%), Positives = 18/30 (60%)

Query: 227 EELHPTATVLKAQFPSVAVEASGGITLDNL 256
           E++ P    L+ QFPS+ +E  GG+  D +
Sbjct: 154 EDMMPKVHWLRTQFPSLDIEGDGGVGSDTV 183


>gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo
           sapiens]
          Length = 2146

 Score = 28.1 bits (61), Expect = 9.7
 Identities = 20/59 (33%), Positives = 28/59 (47%)

Query: 100 GERVALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAA 158
           G RVA + L+  +      + A+   +G G   H  GTR T   F L +  GLL+  AA
Sbjct: 684 GGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNVGTRPTADVFSLAQVSGLLLLDAA 742


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,179,467
Number of Sequences: 37866
Number of extensions: 478560
Number of successful extensions: 1220
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1208
Number of HSP's gapped (non-prelim): 23
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.