Guide to the Human Genome
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Search of human proteins with 4507813

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507813 UDP-glucose dehydrogenase [Homo sapiens]
         (494 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507813 UDP-glucose dehydrogenase [Homo sapiens]                   993   0.0  
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi...    32   1.7  
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]                  32   1.7  
gi|182509180 zinc finger and BTB domain containing 1 isoform 1 [...    31   2.3  
gi|182509178 zinc finger and BTB domain containing 1 isoform 2 [...    31   2.3  
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid...    30   5.0  
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...    30   5.0  
gi|150378535 sarcoglycan, epsilon isoform 3 [Homo sapiens]             30   6.6  
gi|218505680 exoribonuclease 2 isoform 1 [Homo sapiens]                30   6.6  
gi|218505674 exoribonuclease 2 isoform 2 [Homo sapiens]                30   6.6  
gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens]      29   8.6  
gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec...    29   8.6  
gi|18087809 ATP binding domain 4 isoform 1 [Homo sapiens]              29   8.6  

>gi|4507813 UDP-glucose dehydrogenase [Homo sapiens]
          Length = 494

 Score =  993 bits (2567), Expect = 0.0
 Identities = 494/494 (100%), Positives = 494/494 (100%)

Query: 1   MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60
           MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV
Sbjct: 1   MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEV 60

Query: 61  VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS 120
           VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS
Sbjct: 61  VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS 120

Query: 121 NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180
           NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI
Sbjct: 121 NGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI 180

Query: 181 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 240
           GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL
Sbjct: 181 GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISAL 240

Query: 241 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 300
           CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW
Sbjct: 241 CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW 300

Query: 301 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 360
           QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE
Sbjct: 301 QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE 360

Query: 361 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 420
           GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF
Sbjct: 361 GAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMF 420

Query: 421 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP 480
           KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP
Sbjct: 421 KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP 480

Query: 481 KFSLQDPPNKKPKV 494
           KFSLQDPPNKKPKV
Sbjct: 481 KFSLQDPPNKKPKV 494


>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
           sapiens]
          Length = 366

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 27/131 (20%), Positives = 56/131 (42%), Gaps = 10/131 (7%)

Query: 233 SINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALN 292
           ++ +I+++C   G +   +   IG +Q   N+     V FG +C+   VL  +Y C    
Sbjct: 2   TVRNIASICNM-GTNASALEKDIGPEQFPINEHYFGLVNFGNTCYCNSVLQALYFCRPFR 60

Query: 293 LPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIY 352
              +A   QQ       +++      +  LF+++  +K  +     KK     R+ + ++
Sbjct: 61  ENVLAYKAQQ-------KKKENLLTCLADLFHSIATQKKKVGVIPPKKFISRLRKENDLF 113

Query: 353 ISKYLMDEGAH 363
            +   M + AH
Sbjct: 114 DN--YMQQDAH 122


>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
          Length = 370

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 15/58 (25%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 231 ISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLC 288
           + +++  +++C   GA+   +   IG +Q   N+     V FG +C+   VL  +Y C
Sbjct: 4   LMTVSKFASIC-TMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFC 60


>gi|182509180 zinc finger and BTB domain containing 1 isoform 1
           [Homo sapiens]
          Length = 713

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 13/98 (13%)

Query: 257 MDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQ----RR 312
           + +R G  F   S GFG SC +K +   V  C   +L +  R + +++D+ D +    + 
Sbjct: 208 VSRRFGRSFTCDSCGFGFSC-EKLLDEHVLTCTNRHLYQNTRSYHRIVDIRDGKDSNIKA 266

Query: 313 RFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSS 350
            F  +     F+  TDK        ++ DT    + S+
Sbjct: 267 EFGEKDSSKTFSAQTDK--------YRGDTSQAADDSA 296


>gi|182509178 zinc finger and BTB domain containing 1 isoform 2
           [Homo sapiens]
          Length = 644

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 13/98 (13%)

Query: 257 MDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQ----RR 312
           + +R G  F   S GFG SC +K +   V  C   +L +  R + +++D+ D +    + 
Sbjct: 208 VSRRFGRSFTCDSCGFGFSC-EKLLDEHVLTCTNRHLYQNTRSYHRIVDIRDGKDSNIKA 266

Query: 313 RFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSS 350
            F  +     F+  TDK        ++ DT    + S+
Sbjct: 267 EFGEKDSSKTFSAQTDK--------YRGDTSQAADDSA 296


>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
            [Homo sapiens]
          Length = 1445

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 13/92 (14%)

Query: 290  ALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNT---VTDKKIAILGFAFKKDTGDTR 346
            +L LPE   +W      +D++R R  +  ++ + N    VT+    +  F  +       
Sbjct: 1255 SLTLPEFPHWWHLPFTNSDHRRFRDLNHYMEQILNVSHEVTNSDCVLSFFLSEAVQQTVE 1314

Query: 347  ESSSIYISKYLMDEGAHLHIYDPKVPREQIVV 378
            ESS +Y+ +   D          K P+ Q+V+
Sbjct: 1315 ESSPVYLGEKFPD----------KKPKVQLVI 1336


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 60/260 (23%), Positives = 101/260 (38%), Gaps = 58/260 (22%)

Query: 87  ISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDA 146
           I V TP + + M   R    KYI+              ++ E   +  R  +   +I+D 
Sbjct: 154 IIVGTPGRVFDMLNRRYLSPKYIKMF------------VLDEADEMLSRGFKD--QIYDI 199

Query: 147 NTKPNLNLQVL----SNPEFLAEGTAIKDLKNPDRVLIGGDE-TPEGQRA---------- 191
             K N N QV+    + P  + E T  K +++P R+L+  +E T EG R           
Sbjct: 200 FQKLNSNTQVVLLSATMPSDVLEVTK-KFMRDPIRILVKKEELTLEGIRQFYINVEREEW 258

Query: 192 -VQALCAVYEHWVPREKILTTNT-----WSSELSKLAANAFLAQRI-------------- 231
            +  LC +YE     + ++  NT     W +E  K+ A  F    +              
Sbjct: 259 KLDTLCDLYETLTITQAVIFINTRRKVDWLTE--KMHARDFTVSAMHGDMDQKERDVIMR 316

Query: 232 -----SSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDV-LNLV 285
                SS   I+    A G DV++V+  I  D     +     +G GG   +K V +N+V
Sbjct: 317 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376

Query: 286 YLCEALNLPEVARYWQQVID 305
              +   L ++  ++   I+
Sbjct: 377 TEEDKRTLRDIETFYNTSIE 396


>gi|150378535 sarcoglycan, epsilon isoform 3 [Homo sapiens]
          Length = 451

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 7   ICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRG 66
           +CC   G +     S I     E+R    D++++R  AW   TLP++ P   E++     
Sbjct: 339 MCCRREGVIQLVHHSAIQKSTKELR----DMSKNREIAWPLSTLPVFHPVTGEIIPPLHT 394

Query: 67  KNLFFSTNI 75
            N + STN+
Sbjct: 395 DN-YDSTNM 402


>gi|218505680 exoribonuclease 2 isoform 1 [Homo sapiens]
          Length = 691

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 11/60 (18%)

Query: 410 AVVICTEWDMFKELDYERIHKKMLKPAFIFDG-----------RRVLDGLHNELQTIGFQ 458
           A V  ++WD+   L+YE   K++LKP F+              RR   GL   LQ +G +
Sbjct: 148 AFVTWSDWDLGVCLEYECKRKQLLKPVFLNSWIDLRATYKLFYRRKPKGLSGALQEVGIE 207


>gi|218505674 exoribonuclease 2 isoform 2 [Homo sapiens]
          Length = 328

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 11/60 (18%)

Query: 410 AVVICTEWDMFKELDYERIHKKMLKPAFIFDG-----------RRVLDGLHNELQTIGFQ 458
           A V  ++WD+   L+YE   K++LKP F+              RR   GL   LQ +G +
Sbjct: 148 AFVTWSDWDLGVCLEYECKRKQLLKPVFLNSWIDLRATYKLFYRRKPKGLSGALQEVGIE 207


>gi|51477721 testis expressed sequence 11 isoform 1 [Homo sapiens]
          Length = 940

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 33/152 (21%), Positives = 61/152 (40%), Gaps = 20/152 (13%)

Query: 153 NLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKI---- 208
           NL++L + +  A  + +         L+  D +P    A+  L +   + + RE +    
Sbjct: 7   NLRLLCSSDSSASASQVAGTTEVVENLVTNDNSPNIPEAIDRLFSDIAN-INRESMAEIT 65

Query: 209 ------LTTNTWSSELSKLAANAFLAQRISSIN------SISALCEATGADVEEVATAIG 256
                 +  N W+  L+      +L      I        + ++CEA+ A  + +   I 
Sbjct: 66  DIQIEEMAVNLWNWALT--IGGGWLVNEEQKIRLHYVACKLLSMCEASFASEQSIQRLIM 123

Query: 257 MDQRIGNKFLKA-SVGFGGSCFQKDVLNLVYL 287
           M+ RIG ++L A +      CFQ  V +L  L
Sbjct: 124 MNMRIGKEWLDAGNFLIADECFQAAVASLEQL 155


>gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2
           precursor [Homo sapiens]
          Length = 437

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 8/98 (8%)

Query: 114 RRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLK 173
           R I  N + +KI+   S++PV   +++R + DA+  P  +L        L   T I +  
Sbjct: 228 RTIQLNVSSFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPAL-NATPISNTG 286

Query: 174 NPDRVLIG----GDETPEGQR---AVQALCAVYEHWVP 204
             +   +G    GD T   Q    ++Q   +++ HW P
Sbjct: 287 VLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKP 324


>gi|18087809 ATP binding domain 4 isoform 1 [Homo sapiens]
          Length = 267

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 10/96 (10%)

Query: 269 SVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTD 328
           SVG   S +Q+  + +  +C+ LNL  +A  WQ+  +  D  R   +S I   +      
Sbjct: 113 SVGAILSDYQR--IRVENVCKRLNLQPLAYLWQR--NQEDLLREMISSNIQAMII----- 163

Query: 329 KKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHL 364
            K+A LG    K  G T +    Y+ +     G H+
Sbjct: 164 -KVAALGLDPDKHLGKTLDQMEPYLIELSKKYGVHV 198


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,463,576
Number of Sequences: 37866
Number of extensions: 791238
Number of successful extensions: 1771
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1768
Number of HSP's gapped (non-prelim): 14
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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