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Search of human proteins with 4507021
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507021 solute carrier family 4, anion exchanger, member 1
[Homo sapiens]
(911 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H... 1795 0.0
gi|156071474 solute carrier family 4, anion exchanger, member 2 ... 1011 0.0
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 954 0.0
gi|157671953 solute carrier family 4, anion exchanger, member 3 ... 954 0.0
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp... 568 e-161
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp... 566 e-161
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans... 564 e-160
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo... 564 e-160
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans... 564 e-160
gi|155722998 solute carrier family 4, sodium bicarbonate transpo... 563 e-160
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap... 534 e-151
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa... 525 e-148
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans... 510 e-144
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans... 496 e-140
gi|14042960 solute carrier family 4 member 11 [Homo sapiens] 244 3e-64
gi|121949802 cancer/testis antigen family 47, member A1 [Homo sa... 38 0.038
gi|121949798 cancer/testis antigen family 47, member A2 [Homo sa... 38 0.038
gi|121949773 cancer/testis antigen family 47, member A3 [Homo sa... 38 0.038
gi|121949771 cancer/testis antigen family 47, member A4 [Homo sa... 38 0.038
gi|121949796 cancer/testis antigen family 47, member A5 [Homo sa... 38 0.038
gi|121949794 cancer/testis antigen family 47, member A6 [Homo sa... 38 0.038
gi|121949792 cancer/testis antigen family 47, member A7 [Homo sa... 38 0.038
gi|121949790 cancer/testis antigen family 47, member A8 [Homo sa... 38 0.038
gi|121949788 cancer/testis antigen family 47, member A9 [Homo sa... 38 0.038
gi|121949786 cancer/testis antigen family 47, member A10 [Homo s... 38 0.038
gi|122114660 cancer/testis antigen family 47, member A11 [Homo s... 38 0.038
gi|6912430 isoprenylcysteine carboxyl methyltransferase [Homo sa... 37 0.084
gi|215272392 solute carrier family 18 (vesicular monoamine), mem... 35 0.24
gi|215272390 solute carrier family 18 (vesicular monoamine), mem... 35 0.24
gi|208879454 solute carrier family 18 (vesicular monoamine), mem... 35 0.24
>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
sapiens]
Length = 911
Score = 1795 bits (4648), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVE 60
MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVE
Sbjct: 1 MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVE 60
Query: 61 LQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHLTFWSLLELRRVFTKGTVL 120
LQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHLTFWSLLELRRVFTKGTVL
Sbjct: 61 LQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHLTFWSLLELRRVFTKGTVL 120
Query: 121 LDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKPAVLTR 180
LDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKPAVLTR
Sbjct: 121 LDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKPAVLTR 180
Query: 181 SGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRADFLEQP 240
SGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRADFLEQP
Sbjct: 181 SGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRADFLEQP 240
Query: 241 VLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYM 300
VLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYM
Sbjct: 241 VLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYM 300
Query: 301 AQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYK 360
AQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYK
Sbjct: 301 AQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYK 360
Query: 361 GLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPA 420
GLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPA
Sbjct: 361 GLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPA 420
Query: 421 ITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCE 480
ITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCE
Sbjct: 421 ITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCE 480
Query: 481 TNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKL 540
TNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKL
Sbjct: 481 TNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKL 540
Query: 541 IKIFQDHPLQKTYNYNVLMVPKPQGPLPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGK 600
IKIFQDHPLQKTYNYNVLMVPKPQGPLPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGK
Sbjct: 541 IKIFQDHPLQKTYNYNVLMVPKPQGPLPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGK 600
Query: 601 LRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFP 660
LRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFP
Sbjct: 601 LRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFP 660
Query: 661 IWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFG 720
IWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFG
Sbjct: 661 IWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFG 720
Query: 721 MPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPIL 780
MPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPIL
Sbjct: 721 MPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPIL 780
Query: 781 SRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQ 840
SRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQ
Sbjct: 781 SRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQ 840
Query: 841 IICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEG 900
IICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEG
Sbjct: 841 IICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEG 900
Query: 901 RDEYDEVAMPV 911
RDEYDEVAMPV
Sbjct: 901 RDEYDEVAMPV 911
>gi|156071474 solute carrier family 4, anion exchanger, member 2
(erythrocyte membrane protein band 3-like 1) [Homo
sapiens]
Length = 1241
Score = 1011 bits (2613), Expect = 0.0
Identities = 539/926 (58%), Positives = 682/926 (73%), Gaps = 74/926 (7%)
Query: 55 HKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLELRRV 113
H+V+VEL EL++D KNQE +W E ARW++ EE++ E WG+PH++ L+F SLLELRR
Sbjct: 321 HEVFVELNELLLD-KNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 379
Query: 114 FTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSH---------- 163
G VLLDL + +L GVA+Q++++ + DQI+ +DR +LRALLLKHSH
Sbjct: 380 LAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFP 439
Query: 164 ----AGELEALGGVKPAVLTRSGDP--SQPLLPQHSSLETQLFCEQGDGGTEGHSPSGI- 216
AG L +L G S DP ++PL+ ET+L E+ P+GI
Sbjct: 440 RNISAGSLGSLLGHHHGQGAES-DPHVTEPLMG--GVPETRLEVERERELPPPAPPAGIT 496
Query: 217 ----------LEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFL 265
LEKIP ++EAT+VLVG +FL +P + FVRL+EA EL+AV E+PVP+RFL
Sbjct: 497 RSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFL 556
Query: 266 FVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTD 325
F+LLGP + ++DY ++GR+ +TLMS++ F AY+A R +LL ++ FLDCS+VLPP++
Sbjct: 557 FLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSE 616
Query: 326 APSEQALLSLVPVQRELLRRRYQSSPAKP-----------DSSFYKGLDLNGGP-DDPLQ 373
E+ L S+ QR++L++R + P D + + ++ G DDPL+
Sbjct: 617 VQGEELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLR 676
Query: 374 QTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRN 433
+TG+ FGGL+RD+RRRYP+YLSD DA PQ LAAVIFIYFAALSPAITFGGLLGEKT++
Sbjct: 677 RTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQD 736
Query: 434 QMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWI 493
+GVSEL++STA+QG++F LLGAQPLLV+GFSGPLLVFEEAFFSFC +N LEY+VGRVWI
Sbjct: 737 LIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWI 796
Query: 494 GFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTY 553
GFWL+ L +L+VA EGSFLVRF+SR+TQEIF+FLISLIFIYETF KL+KIFQ+HPL
Sbjct: 797 GFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCS 856
Query: 554 NYNVLMVP----------------------------KPQGPLPNTALLSLVLMAGTFFFA 585
N V KP+G PNTALLSLVLMAGTFF A
Sbjct: 857 ASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQGKPRGQ-PNTALLSLVLMAGTFFIA 915
Query: 586 MMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSA 645
LRKFKNS +FPG++RRVIGDFGVPI+ILIMVLVD+ I+DTYTQKLSVP GF V+
Sbjct: 916 FFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEK 975
Query: 646 RGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLD 705
RGWVI+PLG +S FP+WMM AS LPA+LVFILIF+E+QITTLI+SK ER + KGSGFHLD
Sbjct: 976 RGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKGSGFHLD 1035
Query: 706 LLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLL 765
LLL+V MGG+ ALFG+PWL+A TVRSVTHANALTVM KA PG +IQEVKEQR++GLL
Sbjct: 1036 LLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQRVTGLL 1095
Query: 766 VAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYV 825
VA+LVGLSI++ +L +IPLAVLFGIFLYMGVTSL+GIQ ++R+ LL PPK+HPDV YV
Sbjct: 1096 VALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYV 1155
Query: 826 KRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQC 885
K+V+T RMHLFT +Q++CLA+LW V ST ASLA PF+LILTVPLR V+L IF + E++C
Sbjct: 1156 KKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKC 1215
Query: 886 LDADDAKATFDEEEGRDEYDEVAMPV 911
LDA++A+ FDE EG DEY+E+ MPV
Sbjct: 1216 LDANEAEPVFDEREGVDEYNEMPMPV 1241
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 954 bits (2466), Expect = 0.0
Identities = 512/918 (55%), Positives = 642/918 (69%), Gaps = 65/918 (7%)
Query: 55 HKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLELRRV 113
H+V+VEL EL++D ++QE W E ARW++ EE++ E WG+PH++ L+F SLLELRR
Sbjct: 319 HEVFVELNELMLD-RSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 377
Query: 114 FTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALG-- 171
G LLDL++T+L G+A+ +++ I DQIRP+DR +LR LLLKHSH + + G
Sbjct: 378 IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFF 437
Query: 172 -------------------------GVKPAVLTRSGDPSQPLLPQHSSLETQLFCEQGDG 206
G P + G+P+ PL P + + G
Sbjct: 438 PRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPA-PLWPHDPDAKEKPLHMPGGD 496
Query: 207 GTEGHSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFL 265
G G S +LEKIP D+EAT+VLVG FLEQP FVRL EA LE+V E+PVP+RFL
Sbjct: 497 GHRGKSLK-LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFL 555
Query: 266 FVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTD 325
FV+LGP DY +LGR+ ATLMS+++F AY A R +LL ++ FLD S+V+PP++
Sbjct: 556 FVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSE 615
Query: 326 APSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYKG---------LDLNGGP----DDPL 372
L S+ QRELLR+R + K + + G L+L G DDPL
Sbjct: 616 VEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDPL 675
Query: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432
+TG +FGGLVRD+RRRYP+Y SD+ DA Q +AAV+FIYFAALSPAITFGGLLGEKT
Sbjct: 676 LRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTE 735
Query: 433 NQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVW 492
MGVSEL++STAV G+LF+LLGAQPLLVVGFSGPLLVFEEAFF FC LEY+ GRVW
Sbjct: 736 GLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVW 795
Query: 493 IGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKT 552
+G WL++ V+ +VA EGSFLVR+IS +TQEIF+FLISLIFIYETF KL K+F +HPL
Sbjct: 796 VGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPLLPF 855
Query: 553 Y--------------NYNVLMVPKPQGP-----LPNTALLSLVLMAGTFFFAMMLRKFKN 593
Y N +P +GP PNTALLSL+LM GTFF A LRKF+N
Sbjct: 856 YPPEGALEGSLDAGLEPNGSALPPTEGPPSPRNQPNTALLSLILMLGTFFIAFFLRKFRN 915
Query: 594 SSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPL 653
S + GK RR+IGDFG+PISIL+MVLVD+ I DTYTQKL+VP G V++ R W I PL
Sbjct: 916 SRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPL 975
Query: 654 GLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMG 713
G FP WMM A+A+PALLV ILIF+E+QIT LIVS+ R+++KGSGFHLDLLL+ +G
Sbjct: 976 GSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLG 1035
Query: 714 GVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLS 773
G+ LFG+PWL+A TVRSVTH NALTVM A PG QIQEV+EQR++G+L+A LVGLS
Sbjct: 1036 GLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLS 1095
Query: 774 ILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRM 833
I+M +L RIPLAVLFGIFLYMGVTSLSGIQL R+LL+ P K+HP+ PYV +VKTWRM
Sbjct: 1096 IVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRM 1155
Query: 834 HLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKA 893
HLFT IQ+ C+A+LWVVKST ASLA PF+L+LTVPLR LLP +F++ ELQ LD++DA+
Sbjct: 1156 HLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEP 1215
Query: 894 TFDEEEGRDEYDEVAMPV 911
FD E+G+DEY+E+ MPV
Sbjct: 1216 NFD-EDGQDEYNELHMPV 1232
>gi|157671953 solute carrier family 4, anion exchanger, member 3
isoform 2 [Homo sapiens]
Length = 1259
Score = 954 bits (2466), Expect = 0.0
Identities = 512/918 (55%), Positives = 642/918 (69%), Gaps = 65/918 (7%)
Query: 55 HKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLELRRV 113
H+V+VEL EL++D ++QE W E ARW++ EE++ E WG+PH++ L+F SLLELRR
Sbjct: 346 HEVFVELNELMLD-RSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 404
Query: 114 FTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALG-- 171
G LLDL++T+L G+A+ +++ I DQIRP+DR +LR LLLKHSH + + G
Sbjct: 405 IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFF 464
Query: 172 -------------------------GVKPAVLTRSGDPSQPLLPQHSSLETQLFCEQGDG 206
G P + G+P+ PL P + + G
Sbjct: 465 PRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPA-PLWPHDPDAKEKPLHMPGGD 523
Query: 207 GTEGHSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFL 265
G G S +LEKIP D+EAT+VLVG FLEQP FVRL EA LE+V E+PVP+RFL
Sbjct: 524 GHRGKSLK-LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFL 582
Query: 266 FVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTD 325
FV+LGP DY +LGR+ ATLMS+++F AY A R +LL ++ FLD S+V+PP++
Sbjct: 583 FVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSE 642
Query: 326 APSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYKG---------LDLNGGP----DDPL 372
L S+ QRELLR+R + K + + G L+L G DDPL
Sbjct: 643 VEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDPL 702
Query: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432
+TG +FGGLVRD+RRRYP+Y SD+ DA Q +AAV+FIYFAALSPAITFGGLLGEKT
Sbjct: 703 LRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTE 762
Query: 433 NQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVW 492
MGVSEL++STAV G+LF+LLGAQPLLVVGFSGPLLVFEEAFF FC LEY+ GRVW
Sbjct: 763 GLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVW 822
Query: 493 IGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKT 552
+G WL++ V+ +VA EGSFLVR+IS +TQEIF+FLISLIFIYETF KL K+F +HPL
Sbjct: 823 VGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPLLPF 882
Query: 553 Y--------------NYNVLMVPKPQGP-----LPNTALLSLVLMAGTFFFAMMLRKFKN 593
Y N +P +GP PNTALLSL+LM GTFF A LRKF+N
Sbjct: 883 YPPEGALEGSLDAGLEPNGSALPPTEGPPSPRNQPNTALLSLILMLGTFFIAFFLRKFRN 942
Query: 594 SSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPL 653
S + GK RR+IGDFG+PISIL+MVLVD+ I DTYTQKL+VP G V++ R W I PL
Sbjct: 943 SRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPL 1002
Query: 654 GLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMG 713
G FP WMM A+A+PALLV ILIF+E+QIT LIVS+ R+++KGSGFHLDLLL+ +G
Sbjct: 1003 GSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLG 1062
Query: 714 GVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLS 773
G+ LFG+PWL+A TVRSVTH NALTVM A PG QIQEV+EQR++G+L+A LVGLS
Sbjct: 1063 GLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLS 1122
Query: 774 ILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRM 833
I+M +L RIPLAVLFGIFLYMGVTSLSGIQL R+LL+ P K+HP+ PYV +VKTWRM
Sbjct: 1123 IVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRM 1182
Query: 834 HLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKA 893
HLFT IQ+ C+A+LWVVKST ASLA PF+L+LTVPLR LLP +F++ ELQ LD++DA+
Sbjct: 1183 HLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEP 1242
Query: 894 TFDEEEGRDEYDEVAMPV 911
FD E+G+DEY+E+ MPV
Sbjct: 1243 NFD-EDGQDEYNELHMPV 1259
>gi|90403614 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform a [Homo sapiens]
Length = 1093
Score = 568 bits (1463), Expect = e-161
Identities = 350/966 (36%), Positives = 533/966 (55%), Gaps = 109/966 (11%)
Query: 33 EPAAHDTEATATDYHTTSHPGT----HKVYVELQELVMDEKNQELRWMEAARWVQLEENL 88
E AHDT + + + H+++ EL E+ M E ++ W E ARW++ EE++
Sbjct: 88 EALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKE-GEDAEWKETARWLKFEEDV 146
Query: 89 GENGA-WGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRP 147
+ G W +P+++ L+ SL ELR GTVLLD+ S+ +++ +LD+ +
Sbjct: 147 EDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLND 206
Query: 148 QDREELLRALLLKHSHAGELE-----------ALGGVK---PAVLTRSGDPSQPLLPQHS 193
R ++ ALL KH H E + A G K P ++ + G P +
Sbjct: 207 SMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTT 266
Query: 194 SLETQLFCEQGDGGTEGHSPSGI-------LEKIPPDSEATLVLVGRADFLEQPVLGFVR 246
+LE + +G HSP + ++KIP +EA+ VLVG D L++P++ FVR
Sbjct: 267 NLEVK------NGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVR 320
Query: 247 LQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRG 305
L A L + E+P+P RFLF+LLGP Y ++GR+ AT+M++ +F AY A+ R
Sbjct: 321 LSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERD 380
Query: 306 ELLHSLEGFLDCSLVLPPTD-APSEQALLSLVPVQRELLRRRYQSSPAKPDSSF-YKGLD 363
+LL ++ FLD VLPP + PS + + + + + + P P+ + + +
Sbjct: 381 DLLAGIDEFLDQVTVLPPGEWDPSIR-----IEPPKNVPSQEKRKMPGVPNGNVCHIEQE 435
Query: 364 LNGGPDDP-LQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAIT 422
+GG P LQ+TG+LFGGLV DI+R+ P+Y SD DA S Q LA+ +F+Y A +SP IT
Sbjct: 436 PHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVIT 495
Query: 423 FGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETN 482
FGGLLGE T ++ E L ++ GI ++L Q L ++G +GP+LVFE+ F FC+
Sbjct: 496 FGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDY 555
Query: 483 GLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIK 542
L Y+ R IG W L +++VA + S LV +I+R+T+E F+ LI +IFIYE KLI
Sbjct: 556 ALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIH 615
Query: 543 IFQ---------------------------DHPLQKTYNYNV---------LMVPKPQ-- 564
+ + +H LQ ++N+ L V + Q
Sbjct: 616 LAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEM 675
Query: 565 ------------GP-LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVP 611
GP P+ S +L TF + L+ FK S YFP ++R ++ DF V
Sbjct: 676 HGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVF 735
Query: 612 ISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPA 671
++I MV++DF I + KL VP FK + RGW+I+P+G P W + A+ +PA
Sbjct: 736 LTIFTMVIIDFLI-GVPSPKLQVPSVFKPTRDD-RGWIINPIGPN---PWWTVIAAIIPA 790
Query: 672 LLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRS 731
LL ILIF++ QIT +I+++ E K+ KG G+HLDLL+V M GV ++ G+PW A TV S
Sbjct: 791 LLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLS 850
Query: 732 VTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGI 791
+TH N+L + + S PG + ++EQR++GL++ VL+G S+ M IL IP+ VL+G+
Sbjct: 851 ITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGV 910
Query: 792 FLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVK 851
FLYMGV+SL GIQ FDR+ L P K+ PD Y++ V ++HLFT IQ+ CL +LWV+K
Sbjct: 911 FLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIK 970
Query: 852 STPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD----------ADDAKATFDEEEGR 901
++PA++ P +++ V +R+V + L F EL LD DDAK EEE
Sbjct: 971 ASPAAIVFPMMVLALVFVRKV-MDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEEA 1029
Query: 902 DEYDEV 907
++ E+
Sbjct: 1030 EKMLEI 1035
>gi|90568034 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform b [Homo sapiens]
Length = 1044
Score = 567 bits (1460), Expect = e-161
Identities = 349/958 (36%), Positives = 529/958 (55%), Gaps = 109/958 (11%)
Query: 33 EPAAHDTEATATDYHTTSHPGT----HKVYVELQELVMDEKNQELRWMEAARWVQLEENL 88
E AHDT + + + H+++ EL E+ M E ++ W E ARW++ EE++
Sbjct: 88 EALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKE-GEDAEWKETARWLKFEEDV 146
Query: 89 GENGA-WGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRP 147
+ G W +P+++ L+ SL ELR GTVLLD+ S+ +++ +LD+ +
Sbjct: 147 EDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLND 206
Query: 148 QDREELLRALLLKHSHAGELE-----------ALGGVK---PAVLTRSGDPSQPLLPQHS 193
R ++ ALL KH H E + A G K P ++ + G P +
Sbjct: 207 SMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTT 266
Query: 194 SLETQLFCEQGDGGTEGHSPSGI-------LEKIPPDSEATLVLVGRADFLEQPVLGFVR 246
+LE + +G HSP + ++KIP +EA+ VLVG D L++P++ FVR
Sbjct: 267 NLEVK------NGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVR 320
Query: 247 LQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRG 305
L A L + E+P+P RFLF+LLGP Y ++GR+ AT+M++ +F AY A+ R
Sbjct: 321 LSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERD 380
Query: 306 ELLHSLEGFLDCSLVLPPTD-APSEQALLSLVPVQRELLRRRYQSSPAKPDSSF-YKGLD 363
+LL ++ FLD VLPP + PS + + + + + + P P+ + + +
Sbjct: 381 DLLAGIDEFLDQVTVLPPGEWDPSIR-----IEPPKNVPSQEKRKMPGVPNGNVCHIEQE 435
Query: 364 LNGGPDDP-LQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAIT 422
+GG P LQ+TG+LFGGLV DI+R+ P+Y SD DA S Q LA+ +F+Y A +SP IT
Sbjct: 436 PHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVIT 495
Query: 423 FGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETN 482
FGGLLGE T ++ E L ++ GI ++L Q L ++G +GP+LVFE+ F FC+
Sbjct: 496 FGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDY 555
Query: 483 GLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIK 542
L Y+ R IG W L +++VA + S LV +I+R+T+E F+ LI +IFIYE KLI
Sbjct: 556 ALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIH 615
Query: 543 IFQ---------------------------DHPLQKTYNYNV---------LMVPKPQ-- 564
+ + +H LQ ++N+ L V + Q
Sbjct: 616 LAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEM 675
Query: 565 ------------GP-LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVP 611
GP P+ S +L TF + L+ FK S YFP ++R ++ DF V
Sbjct: 676 HGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVF 735
Query: 612 ISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPA 671
++I MV++DF I + KL VP FK + RGW+I+P+G P W + A+ +PA
Sbjct: 736 LTIFTMVIIDFLI-GVPSPKLQVPSVFKPTRDD-RGWIINPIGPN---PWWTVIAAIIPA 790
Query: 672 LLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRS 731
LL ILIF++ QIT +I+++ E K+ KG G+HLDLL+V M GV ++ G+PW A TV S
Sbjct: 791 LLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLS 850
Query: 732 VTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGI 791
+TH N+L + + S PG + ++EQR++GL++ VL+G S+ M IL IP+ VL+G+
Sbjct: 851 ITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGV 910
Query: 792 FLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVK 851
FLYMGV+SL GIQ FDR+ L P K+ PD Y++ V ++HLFT IQ+ CL +LWV+K
Sbjct: 911 FLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIK 970
Query: 852 STPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD----------ADDAKATFDEEE 899
++PA++ P +++ V +R+V + L F EL LD DDAK EEE
Sbjct: 971 ASPAAIVFPMMVLALVFVRKV-MDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEE 1027
>gi|197927160 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 3 [Homo sapiens]
Length = 1094
Score = 564 bits (1453), Expect = e-160
Identities = 341/933 (36%), Positives = 517/933 (55%), Gaps = 99/933 (10%)
Query: 52 PGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLEL 110
P +++ EL EL+ + QE+ W E ARW++ EE + + G W +PH++ L+ SL EL
Sbjct: 103 PAPPQLFTELDELLAVD-GQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFEL 161
Query: 111 RRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHA---GEL 167
R KG+++LD + +SL + ++D I ++P+ ++++ LL KH H L
Sbjct: 162 RTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNL 221
Query: 168 EALGGVKPAVLTRSG-----DPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPP 222
+L + V + S D P + H +L + + D + + ++K+P
Sbjct: 222 RSLADIGKTVSSASRMFTNPDNGSPAMT-HRNLTSSSLNDISDKPEKDQLKNKFMKKLPR 280
Query: 223 DSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQL 281
D+EA+ VLVG DFL+ P + FVRLQ+A L A+ E+PVP RFLF+LLGP+ Y ++
Sbjct: 281 DAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEI 340
Query: 282 GRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRE 341
GRA ATLMS+ VF AY A+ R +L+ ++ FLD +VLPP + ++ E
Sbjct: 341 GRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPA--------IRIE 392
Query: 342 LLRRRYQSSPAKPDSSFYKGLDLNG-------------GPDDPLQQTGQLFGGLVRDIRR 388
+ S K S + + +NG G + LQ+TG+ GGL++DI+R
Sbjct: 393 PPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKR 452
Query: 389 RYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQG 448
+ P++ SD DA + Q L+A++FIY A ++ AITFGGLLG+ T N GV E + TAV G
Sbjct: 453 KAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSG 512
Query: 449 ILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFE 508
+F L QPL ++ +GP+LVFE F+F + N +Y+ R+WIG W L +++VA +
Sbjct: 513 AIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATD 572
Query: 509 GSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTY--NYNVLMVPKPQGP 566
SFLV++ +R+T+E FS LIS IFIY+ F K+IK+ +P+ + YN L P
Sbjct: 573 ASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP 632
Query: 567 LPNTALLS---------LVLMAG-------TFFFAMMLRK-------------------- 590
P +S L M+ TF +A + +K
Sbjct: 633 DPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692
Query: 591 --------------------FKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQ 630
FK S YFP R++I DF + +SILI ++D + T
Sbjct: 693 TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALV-GVDTP 751
Query: 631 KLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVS 690
KL VP FK S RGW + P G E P W+ A+A+PALLV ILIF++ QIT +IV+
Sbjct: 752 KLIVPSEFK-PTSPNRGWFVPPFG---ENPWWVCLAAAIPALLVTILIFMDQQITAVIVN 807
Query: 691 KPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAA 750
+ E K+ KG+G+HLDL V + + +L +PW A TV S+ H ++L + + S PG
Sbjct: 808 RKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQ 867
Query: 751 AQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRIL 810
+ V+EQR++G LV +L GLS+ M PIL IP+ VL+G+FLYMGV SL+G+Q DR+
Sbjct: 868 PKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLK 927
Query: 811 LLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLR 870
LL P K+ PD Y++ V R+HLFT +Q++CLA+LW++KST A++ P +++ V +R
Sbjct: 928 LLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVR 987
Query: 871 RVLLPLIFRNVELQCLDADDAKATFDEEEGRDE 903
+ + +F +L L DD D+++ DE
Sbjct: 988 KG-MDYLFSQHDLSFL--DDVIPEKDKKKKEDE 1017
>gi|4507025 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 2 [Homo sapiens]
Length = 1035
Score = 564 bits (1453), Expect = e-160
Identities = 341/933 (36%), Positives = 517/933 (55%), Gaps = 99/933 (10%)
Query: 52 PGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLEL 110
P +++ EL EL+ + QE+ W E ARW++ EE + + G W +PH++ L+ SL EL
Sbjct: 59 PAPPQLFTELDELLAVD-GQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFEL 117
Query: 111 RRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHA---GEL 167
R KG+++LD + +SL + ++D I ++P+ ++++ LL KH H L
Sbjct: 118 RTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNL 177
Query: 168 EALGGVKPAVLTRSG-----DPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPP 222
+L + V + S D P + H +L + + D + + ++K+P
Sbjct: 178 RSLADIGKTVSSASRMFTNPDNGSPAMT-HRNLTSSSLNDISDKPEKDQLKNKFMKKLPR 236
Query: 223 DSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQL 281
D+EA+ VLVG DFL+ P + FVRLQ+A L A+ E+PVP RFLF+LLGP+ Y ++
Sbjct: 237 DAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEI 296
Query: 282 GRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRE 341
GRA ATLMS+ VF AY A+ R +L+ ++ FLD +VLPP + ++ E
Sbjct: 297 GRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPA--------IRIE 348
Query: 342 LLRRRYQSSPAKPDSSFYKGLDLNG-------------GPDDPLQQTGQLFGGLVRDIRR 388
+ S K S + + +NG G + LQ+TG+ GGL++DI+R
Sbjct: 349 PPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKR 408
Query: 389 RYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQG 448
+ P++ SD DA + Q L+A++FIY A ++ AITFGGLLG+ T N GV E + TAV G
Sbjct: 409 KAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSG 468
Query: 449 ILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFE 508
+F L QPL ++ +GP+LVFE F+F + N +Y+ R+WIG W L +++VA +
Sbjct: 469 AIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATD 528
Query: 509 GSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTY--NYNVLMVPKPQGP 566
SFLV++ +R+T+E FS LIS IFIY+ F K+IK+ +P+ + YN L P
Sbjct: 529 ASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP 588
Query: 567 LPNTALLS---------LVLMAG-------TFFFAMMLRK-------------------- 590
P +S L M+ TF +A + +K
Sbjct: 589 DPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 648
Query: 591 --------------------FKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQ 630
FK S YFP R++I DF + +SILI ++D + T
Sbjct: 649 TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALV-GVDTP 707
Query: 631 KLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVS 690
KL VP FK S RGW + P G E P W+ A+A+PALLV ILIF++ QIT +IV+
Sbjct: 708 KLIVPSEFK-PTSPNRGWFVPPFG---ENPWWVCLAAAIPALLVTILIFMDQQITAVIVN 763
Query: 691 KPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAA 750
+ E K+ KG+G+HLDL V + + +L +PW A TV S+ H ++L + + S PG
Sbjct: 764 RKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQ 823
Query: 751 AQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRIL 810
+ V+EQR++G LV +L GLS+ M PIL IP+ VL+G+FLYMGV SL+G+Q DR+
Sbjct: 824 PKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLK 883
Query: 811 LLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLR 870
LL P K+ PD Y++ V R+HLFT +Q++CLA+LW++KST A++ P +++ V +R
Sbjct: 884 LLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVR 943
Query: 871 RVLLPLIFRNVELQCLDADDAKATFDEEEGRDE 903
+ + +F +L L DD D+++ DE
Sbjct: 944 KG-MDYLFSQHDLSFL--DDVIPEKDKKKKEDE 973
>gi|148596928 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 1 [Homo sapiens]
Length = 1079
Score = 564 bits (1453), Expect = e-160
Identities = 341/933 (36%), Positives = 517/933 (55%), Gaps = 99/933 (10%)
Query: 52 PGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLEL 110
P +++ EL EL+ + QE+ W E ARW++ EE + + G W +PH++ L+ SL EL
Sbjct: 103 PAPPQLFTELDELLAVD-GQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFEL 161
Query: 111 RRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHA---GEL 167
R KG+++LD + +SL + ++D I ++P+ ++++ LL KH H L
Sbjct: 162 RTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNL 221
Query: 168 EALGGVKPAVLTRSG-----DPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPP 222
+L + V + S D P + H +L + + D + + ++K+P
Sbjct: 222 RSLADIGKTVSSASRMFTNPDNGSPAMT-HRNLTSSSLNDISDKPEKDQLKNKFMKKLPR 280
Query: 223 DSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQL 281
D+EA+ VLVG DFL+ P + FVRLQ+A L A+ E+PVP RFLF+LLGP+ Y ++
Sbjct: 281 DAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEI 340
Query: 282 GRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRE 341
GRA ATLMS+ VF AY A+ R +L+ ++ FLD +VLPP + ++ E
Sbjct: 341 GRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPA--------IRIE 392
Query: 342 LLRRRYQSSPAKPDSSFYKGLDLNG-------------GPDDPLQQTGQLFGGLVRDIRR 388
+ S K S + + +NG G + LQ+TG+ GGL++DI+R
Sbjct: 393 PPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKR 452
Query: 389 RYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQG 448
+ P++ SD DA + Q L+A++FIY A ++ AITFGGLLG+ T N GV E + TAV G
Sbjct: 453 KAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSG 512
Query: 449 ILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFE 508
+F L QPL ++ +GP+LVFE F+F + N +Y+ R+WIG W L +++VA +
Sbjct: 513 AIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATD 572
Query: 509 GSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTY--NYNVLMVPKPQGP 566
SFLV++ +R+T+E FS LIS IFIY+ F K+IK+ +P+ + YN L P
Sbjct: 573 ASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP 632
Query: 567 LPNTALLS---------LVLMAG-------TFFFAMMLRK-------------------- 590
P +S L M+ TF +A + +K
Sbjct: 633 DPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692
Query: 591 --------------------FKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQ 630
FK S YFP R++I DF + +SILI ++D + T
Sbjct: 693 TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALV-GVDTP 751
Query: 631 KLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVS 690
KL VP FK S RGW + P G E P W+ A+A+PALLV ILIF++ QIT +IV+
Sbjct: 752 KLIVPSEFK-PTSPNRGWFVPPFG---ENPWWVCLAAAIPALLVTILIFMDQQITAVIVN 807
Query: 691 KPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAA 750
+ E K+ KG+G+HLDL V + + +L +PW A TV S+ H ++L + + S PG
Sbjct: 808 RKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQ 867
Query: 751 AQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRIL 810
+ V+EQR++G LV +L GLS+ M PIL IP+ VL+G+FLYMGV SL+G+Q DR+
Sbjct: 868 PKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLK 927
Query: 811 LLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLR 870
LL P K+ PD Y++ V R+HLFT +Q++CLA+LW++KST A++ P +++ V +R
Sbjct: 928 LLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVR 987
Query: 871 RVLLPLIFRNVELQCLDADDAKATFDEEEGRDE 903
+ + +F +L L DD D+++ DE
Sbjct: 988 KG-MDYLFSQHDLSFL--DDVIPEKDKKKKEDE 1017
>gi|155722998 solute carrier family 4, sodium bicarbonate
transporter-like, member 10 [Homo sapiens]
Length = 1088
Score = 563 bits (1451), Expect = e-160
Identities = 333/933 (35%), Positives = 523/933 (56%), Gaps = 94/933 (10%)
Query: 55 HKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLELRRV 113
H ++ EL E+ E ++ W E ARW++ EE++ + G W +P+++ L+ SL ELR
Sbjct: 115 HDLFTELDEICWRE-GEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSC 173
Query: 114 FTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGV 173
GTVLLD+ +L +A+ +LD+ + Q+ R + AL+ +H H + + +
Sbjct: 174 ILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRI 233
Query: 174 KPAVLT------RSGDPS-------QPLLPQHSSLETQLFCEQGDGGTEGHSPS------ 214
P V + + +P+ Q + PQ + + + D E +
Sbjct: 234 -PIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVE---NKNDVSRENSTVDFSKVDL 289
Query: 215 GILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEA 273
++KIPP +EA+ +LVG +FL++ V+ FVRL A L+ + E+P+P RFLF+LLGP
Sbjct: 290 HFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLG 349
Query: 274 PHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTD-APSEQAL 332
Y ++GR+ ATLM++ VF AY A+ R +L+ ++ FLD VLPP + PS +
Sbjct: 350 KGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIR-- 407
Query: 333 LSLVPVQRELLRRRYQSSPAKPDSSFYKG-LDLNGGPDDP-LQQTGQLFGGLVRDIRRRY 390
+ + + + + PA P+ + G + +GG P LQ+TG++FGGL+ DI+R+
Sbjct: 408 ---IEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKA 464
Query: 391 PYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGIL 450
PY+ SD DAFS Q LA+ +F+Y A +SP ITFGGLLGE T ++ E L ++ GI
Sbjct: 465 PYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIA 524
Query: 451 FALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGS 510
++L G QPL ++G +GP+LVFE+ F FC+ GL Y+ R IG W L +++VA + S
Sbjct: 525 YSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDAS 584
Query: 511 FLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLM-----VPKPQG 565
LV +I+R+T+E F+ LI +IFIYE KL ++ + +P+ + +L +P
Sbjct: 585 SLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHN 644
Query: 566 P----------------------------------------------LPNTALLSLVLMA 579
P +P+ S++L
Sbjct: 645 PSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFF 704
Query: 580 GTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFK 639
T + L++FK S YFP K+R ++ DF V ++IL MVL+D+ I + KL VP FK
Sbjct: 705 STVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAI-GIPSPKLQVPSVFK 763
Query: 640 VSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKG 699
+ RGW + PLG P W + A+ +PALL ILIF++ QIT +I+++ E K+ KG
Sbjct: 764 PTRDD-RGWFVTPLGPN---PWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKG 819
Query: 700 SGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQ 759
G+HLDLL+V M GV ++ G+PW A TV S+TH N+L + + S PG + ++EQ
Sbjct: 820 CGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQ 879
Query: 760 RISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYH 819
R++GL++ +L+G S+ M IL IP+ VL+G+FLYMG +SL GIQ FDRI L + P K+
Sbjct: 880 RVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQ 939
Query: 820 PDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFR 879
PD Y++ V ++HLFT IQ+ CL +LW++K + A++ P +++ V +R+ L+ L+F
Sbjct: 940 PDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRK-LMDLLFT 998
Query: 880 NVELQCLD---ADDAKATFDEEEGRDEYDEVAM 909
EL LD + K ++ E +E +AM
Sbjct: 999 KRELSWLDDLMPESKKKKLEDAEKEEEQSMLAM 1031
>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
Length = 1121
Score = 534 bits (1376), Expect = e-151
Identities = 345/982 (35%), Positives = 514/982 (52%), Gaps = 138/982 (14%)
Query: 29 SQMEEPAAHDTEATATDYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENL 88
S+ PAA + + +P ++ E+ L D ++ W E+ARW++ EE +
Sbjct: 88 SRTRSPAAEQLQDILGEEDEAPNP---TLFTEMDTLQHD--GDQMEWKESARWIKFEEKV 142
Query: 89 GENGA-WGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRP 147
E G W +PH+S L+ SL ELR GTVLLDL SL + + ++++ I + +RP
Sbjct: 143 EEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRP 202
Query: 148 QDREELLRALLLKHSHAGEL---EALGGVKPAVLTRSGDPSQ-----PLLPQHSSLETQL 199
+ RE + LL +H H + +L + +V T + P++ P L H S E
Sbjct: 203 ELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSL--HHSTEDLR 260
Query: 200 FCEQGDGGTEGHSPSG-----------------ILEKIPPDSEATLVLVGRADFLEQPVL 242
+ + G H+ S ++KIP DSEA+ VLVG DFL+QP +
Sbjct: 261 MRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFI 320
Query: 243 GFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMA 301
FVRL ++A L V E+PVP RFLF+LLGP Y ++GRA ATLM + +F AY A
Sbjct: 321 AFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKA 380
Query: 302 QSRGELLHSLEGFLDCSLVL------------PPTDAPS---EQALLSLVPVQRELLRRR 346
++R +L+ ++ FLD +VL PP PS +++ SL + + +
Sbjct: 381 RNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQ--MNGS 438
Query: 347 YQSSPAKPD----------SSFYKGLDLNGGPD--------------DPLQQTGQLFGGL 382
P S G GG + L TG+ FGGL
Sbjct: 439 VGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGL 498
Query: 383 VRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLI 442
DI+R+ P++ SD D F Q ++A++FIY ++ AITFGGLLG+ T N GV E +
Sbjct: 499 CLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFL 558
Query: 443 STAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVV 502
TA+ G LF L QPL+++ +GP+L+FE+ F F + NGL+Y+ R+WIG + +
Sbjct: 559 GTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCL 618
Query: 503 LVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQK----------- 551
++VA + SF++++I+R+T+E FS LIS IFIY+ K+I F+ +P+
Sbjct: 619 ILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYK 678
Query: 552 -------TYNYNVLMVPKPQGP-------------------------------------- 566
T N V P P
Sbjct: 679 CECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCK 738
Query: 567 -LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQ 625
+P+ AL+S +L GT+ + L+KFK S YFP K+R ++ DF + SIL+ +D
Sbjct: 739 FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACF- 797
Query: 626 DTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQIT 685
T KL VP K + RGW + P G P W+ AS LPALLV ILIF++ QIT
Sbjct: 798 GLETPKLHVPSVIKPTRPD-RGWFVAPFGKN---PWWVYPASILPALLVTILIFMDQQIT 853
Query: 686 TLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKAS 745
+IV++ E K+ K +G+HLDL V + + + G+PW A TV S+ H ++L + + S
Sbjct: 854 AVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETS 913
Query: 746 TPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQL 805
PG Q V+EQR++G++V +L G+S+ + PIL IPL VL+G+FLYMGV SL+GIQ
Sbjct: 914 APGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQF 973
Query: 806 FDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLIL 865
++R L P K+ PD +++ V R+HLFT +QI+CLAVLW++KST A++ P V+IL
Sbjct: 974 WERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFP-VMIL 1032
Query: 866 TVPLRRVLLPLIFRNVELQCLD 887
+ + R LL IF +L +D
Sbjct: 1033 GLIIVRRLLDFIFSQHDLAWID 1054
>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
sapiens]
Length = 1137
Score = 525 bits (1351), Expect = e-148
Identities = 345/998 (34%), Positives = 515/998 (51%), Gaps = 154/998 (15%)
Query: 29 SQMEEPAAHDTEATATDYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENL 88
S+ PAA + + +P ++ E+ L D ++ W E+ARW++ EE +
Sbjct: 88 SRTRSPAAEQLQDILGEEDEAPNP---TLFTEMDTLQHD--GDQMEWKESARWIKFEEKV 142
Query: 89 GENGA-WGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRP 147
E G W +PH+S L+ SL ELR GTVLLDL SL + + ++++ I + +RP
Sbjct: 143 EEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRP 202
Query: 148 QDREELLRALLLKHSHAGEL---EALGGVKPAVLTRSGDPSQ-----PLLPQHSSLETQL 199
+ RE + LL +H H + +L + +V T + P++ P L H S E
Sbjct: 203 ELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSL--HHSTEDLR 260
Query: 200 FCEQGDGGTEGHSPSG-----------------ILEKIPPDSEATLVLVGRADFLEQPVL 242
+ + G H+ S ++KIP DSEA+ VLVG DFL+QP +
Sbjct: 261 MRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFI 320
Query: 243 GFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMA 301
FVRL ++A L V E+PVP RFLF+LLGP Y ++GRA ATLM + +F AY A
Sbjct: 321 AFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKA 380
Query: 302 QSRGELLHSLEGFLDCSLVL------------PPTDAPS---EQALLSLVPVQRELLRRR 346
++R +L+ ++ FLD +VL PP PS +++ SL + + +
Sbjct: 381 RNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQ--MNGS 438
Query: 347 YQSSPAKPD----------SSFYKGLDLNGGPD--------------DPLQQTGQLFGGL 382
P S G GG + L TG+ FGGL
Sbjct: 439 VGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGL 498
Query: 383 VRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLI 442
DI+R+ P++ SD D F Q ++A++FIY ++ AITFGGLLG+ T N GV E +
Sbjct: 499 CLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFL 558
Query: 443 STAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVV 502
TA+ G LF L QPL+++ +GP+L+FE+ F F + NGL+Y+ R+WIG + +
Sbjct: 559 GTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCL 618
Query: 503 LVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQK----------- 551
++VA + SF++++I+R+T+E FS LIS IFIY+ K+I F+ +P+
Sbjct: 619 ILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYK 678
Query: 552 -------TYNYNVLMVPKPQGP-------------------------------------- 566
T N V P P
Sbjct: 679 CECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCK 738
Query: 567 -LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQ 625
+P+ AL+S +L GT+ + L+KFK S YFP K+R ++ DF + SIL+ +D
Sbjct: 739 FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACF- 797
Query: 626 DTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQIT 685
T KL VP K + RGW + P G P W+ AS LPALLV ILIF++ QIT
Sbjct: 798 GLETPKLHVPSVIKPTRPD-RGWFVAPFGKN---PWWVYPASILPALLVTILIFMDQQIT 853
Query: 686 TLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKAS 745
+IV++ E K+ K +G+HLDL V + + + G+PW A TV S+ H ++L + + S
Sbjct: 854 AVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETS 913
Query: 746 TPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQL 805
PG Q V+EQR++G++V +L G+S+ + PIL IPL VL+G+FLYMGV SL+GIQ+
Sbjct: 914 APGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQM 973
Query: 806 ----------------FDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWV 849
++R L P K+ PD +++ V R+HLFT +QI+CLAVLW+
Sbjct: 974 GTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWI 1033
Query: 850 VKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD 887
+KST A++ P V+IL + + R LL IF +L +D
Sbjct: 1034 LKSTVAAIIFP-VMILGLIIVRRLLDFIFSQHDLAWID 1070
>gi|134288865 solute carrier family 4, sodium bicarbonate
cotransporter, member 7 [Homo sapiens]
Length = 1214
Score = 510 bits (1313), Expect = e-144
Identities = 298/781 (38%), Positives = 444/781 (56%), Gaps = 82/781 (10%)
Query: 204 GDGGTEGHSP-------SGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV 256
G GG+ +S + KIP +EA+ VLVG DFLE+P++ FVRL A L +
Sbjct: 399 GSGGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGL 458
Query: 257 -ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFL 315
E+PVP RFLF+LLGP Y ++GR+ ATLM++ +F AY A+ R +LL ++ FL
Sbjct: 459 TEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFL 518
Query: 316 DCSLVLPPTDAPSEQALL--SLVPVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQ 373
D VLPP + + VP Q + + + K + GP+ LQ
Sbjct: 519 DQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPE--LQ 576
Query: 374 QTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRN 433
+TG+LFGGL+ DI+R+ P++LSD DA S Q LA+++F+Y A +SP ITFGGLLGE T
Sbjct: 577 RTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEG 636
Query: 434 QMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWI 493
++ E L ++ GI ++L QPL ++G +GP+LVFE+ + FC L Y+ R I
Sbjct: 637 RISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSI 696
Query: 494 GFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHP----- 548
G W L +++VA + S LV +I+R+T+E F+ LI +IFIYE KL + + +
Sbjct: 697 GLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHN 756
Query: 549 -LQKTYNYNVLMVPKPQ------------------------------------------- 564
L K +Y+ + P
Sbjct: 757 NLDKLTSYSCVCTEPPNPSNETLAQWKKDNITAHNISWRNLTVSECKKLRGVFLGSACGH 816
Query: 565 -GP-LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDF 622
GP +P+ ++L TFF + L++FK YFP K+R I DF V ++I+IMV +D+
Sbjct: 817 HGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDY 876
Query: 623 FIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLES 682
+ + KL VP+ F+ ++ RGW+I PLG + P W + +A+PALL ILIF++
Sbjct: 877 LV-GVPSPKLHVPEKFEPTHPE-RGWIISPLG---DNPWWTLLIAAIPALLCTILIFMDQ 931
Query: 683 QITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMG 742
QIT +I+++ E K+ KG+G+HLDLL+V M GV ++ G+PW A TV S++H N+L V
Sbjct: 932 QITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVES 991
Query: 743 KASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSG 802
+ S PG + ++EQR++GL++ +L+GLS+ M +L IP+ VL+G+FLYMGV+SL G
Sbjct: 992 ECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKG 1051
Query: 803 IQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFV 862
IQLFDRI L P K+ PD+ Y++ V W++H+FT IQ+ CL +LWV+K + A++ P +
Sbjct: 1052 IQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLWVIKVSAAAVVFPMM 1111
Query: 863 LILTVPLRRVLLPLIFRNVELQCLD----------ADDAKATFDEEEGR---DEYDEVAM 909
++ V +R+ L+ L F EL LD DD K EE R D+ D V +
Sbjct: 1112 VLALVFVRK-LMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDDDTVHL 1170
Query: 910 P 910
P
Sbjct: 1171 P 1171
Score = 80.5 bits (197), Expect = 7e-15
Identities = 40/113 (35%), Positives = 66/113 (58%), Gaps = 2/113 (1%)
Query: 55 HKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENG-AWGRPHLSHLTFWSLLELRRV 113
H ++ E+ EL + +E W E ARW++ EE++ + G W +P+++ L+ SL ELR
Sbjct: 110 HDLFTEMDELCYRD-GEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSC 168
Query: 114 FTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGE 166
GTV+LD++ ++L +A+ +LD I Q+ RE + ALL +H H E
Sbjct: 169 ILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVREALLKRHHHQNE 221
>gi|151101449 solute carrier family 4, sodium bicarbonate
cotransporter, member 9 [Homo sapiens]
Length = 959
Score = 496 bits (1277), Expect = e-140
Identities = 320/889 (35%), Positives = 480/889 (53%), Gaps = 88/889 (9%)
Query: 57 VYVELQELVMDEKNQELRWMEAARWVQLEENLG-ENGAWGRPHLSHLTFWSLLELRRVFT 115
++++L EL+ Q L W E RWV EE L G W PH+ L SL +LR +
Sbjct: 56 LFIQLNELL--GWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLA 113
Query: 116 KGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKP 175
+G VLLD SL +L+++ + + P+ R +L LL + H + G +P
Sbjct: 114 EGLVLLDCPAQSLL----ELVEQVTRVESLSPELRGQLQALLLQRPQHYNQTT---GTRP 166
Query: 176 AVLTRSGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRAD 235
S P + + + L Q C+ + + +K+PP +EA VL G
Sbjct: 167 C--WGSTHPRKASDNEEAPLREQ--CQ-----------NPLRQKLPPGAEAGTVLAGELG 211
Query: 236 FLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVF 294
FL QP+ FVRL+ L ++ E+ +P RF +LLGP Y ++GRAAA L+S+ F
Sbjct: 212 FLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQF 271
Query: 295 RIDAYMAQSRGELLHSLEGFLDCSLVLPPT--DAPSEQALLSLVPVQRELL--RRRYQSS 350
+ A + +LL +L+ FL+ VLPP D + +P Q + L ++R
Sbjct: 272 QWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPSQQREIRG 331
Query: 351 PAKPDSSFYKGLDLNG--GPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAA 408
PA P + + +G LQ+TG+LFGGL++D+RR+ P+Y SD DA Q +A
Sbjct: 332 PAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSA 391
Query: 409 VIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPL 468
V++IY A ++ AITFGGLLG+ T GV E + TAV G F L+ QPL ++ +GP+
Sbjct: 392 VLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPV 451
Query: 469 LVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLI 528
LVFE FSF L+Y+ R+W+G W+ +++VA E S LVR+ +R+T+E F LI
Sbjct: 452 LVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFTRFTEEGFCALI 511
Query: 529 SLIFIYETFSKLIKIFQDHPLQK------------------------------------- 551
SLIFIY+ K++ + +P+QK
Sbjct: 512 SLIFIYDAVGKMLNLTHTYPIQKPGSSAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMD 571
Query: 552 --TYNYNVLMVPK-------PQGP----LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFP 598
N ++L P+ P+GP +P+ A SL+L +FFFAM L+ K S +FP
Sbjct: 572 LGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFFP 631
Query: 599 GKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE 658
+R+ + DF ++IL+ +D F+ T KL VP FK RGW++ P G
Sbjct: 632 SVVRKGLSDFSSVLAILLGCGLDAFL-GLATPKLMVPREFK-PTLPGRGWLVSPFGAN-- 687
Query: 659 FPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAAL 718
P W A+ALPALL+ ILIF++ QIT +I+++ E ++ KG+GFHLDL V + + +
Sbjct: 688 -PWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSA 746
Query: 719 FGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEP 778
G+PW + TV S+ H ++L +A PG ++EQR++GL+V +L G SI + P
Sbjct: 747 LGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAP 806
Query: 779 ILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTG 838
+L IP+ VL+GIFLYMGV +LS IQ +R+ LL P K+ PD+ ++ V R+HLFT
Sbjct: 807 VLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTA 866
Query: 839 IQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD 887
IQ+ CL +LW++KSTPA++ P +L+ V +R+ L +F EL LD
Sbjct: 867 IQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKA-LERVFSPQELLWLD 914
>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
Length = 891
Score = 244 bits (622), Expect = 3e-64
Identities = 193/680 (28%), Positives = 314/680 (46%), Gaps = 90/680 (13%)
Query: 262 IRFLFVLLGPEAPHIDYT--QLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSL 319
+RF+ ++L P T ++ R AT+ S+ FR ++ E +L
Sbjct: 247 VRFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALV------- 299
Query: 320 VLPPTDAPSEQALLSLV---PVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQQTG 376
++ LL++V PV R S PA + P+ P +
Sbjct: 300 --------HQRQLLTMVSHGPVAPRTKERSTVSLPA------------HRHPEPPKCKDF 339
Query: 377 QLFG-GLVRDIRRRYPYYLSDITDAFSPQ------VLAAVIFIYFAALSPAITFGGLLGE 429
FG G+ DI RR+P Y D TD + + +F+YFA L P I FG L E
Sbjct: 340 VPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDE 399
Query: 430 KTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVG 489
T + V + + ++ G+L+AL QPL+++ + PL ++ + C+ L++
Sbjct: 400 NTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSF 459
Query: 490 RVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIF----- 544
W G W + L F S ++ R T+EI + IS+ F+ + +KIF
Sbjct: 460 YAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYYY 519
Query: 545 ----QDHPLQKTYNY------------------NVLMVPKPQGPLPN-------TALLSL 575
D+ ++T + N + P LP+ TA+LSL
Sbjct: 520 GHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLASPT-ELPSATHSGQATAVLSL 578
Query: 576 VLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFF-IQDTYTQKLSV 634
++M GT + L +FK S Y +R ++ D +PI++L L+ ++ K
Sbjct: 579 LIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEMSKFR- 637
Query: 635 PDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPER 694
+ S S I L LR+ + A L L+ +L F+E + +V+ PE
Sbjct: 638 ---YNPSESPFAMAQIQSLSLRA-----VSGAMGL-GFLLSMLFFIEQNLVAALVNAPEN 688
Query: 695 KMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQ-I 753
++VKG+ +H DLLL+ + +LFG+PW+ A S H AL ++ + G I
Sbjct: 689 RLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTI 748
Query: 754 QEVKEQRISGLLVAVLVGLSILMEPI-LSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLL 812
VKE R++ L +VLVGLS+L+ P+ L IP VL+G+FLY+ +TSL G QL R+ LL
Sbjct: 749 VNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALL 808
Query: 813 FKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVL--WVVKSTP-ASLALPFVLILTVPL 869
K +P Y++RV ++H FTG+Q++ L +L + + S P + P ++I +P+
Sbjct: 809 LKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPI 868
Query: 870 RRVLLPLIFRNVELQCLDAD 889
R +LLP I L +DA+
Sbjct: 869 RYILLPRIIEAKYLDVMDAE 888
>gi|121949802 cancer/testis antigen family 47, member A1 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949798 cancer/testis antigen family 47, member A2 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949773 cancer/testis antigen family 47, member A3 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949771 cancer/testis antigen family 47, member A4 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949796 cancer/testis antigen family 47, member A5 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949794 cancer/testis antigen family 47, member A6 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949792 cancer/testis antigen family 47, member A7 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949790 cancer/testis antigen family 47, member A8 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949788 cancer/testis antigen family 47, member A9 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|121949786 cancer/testis antigen family 47, member A10 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|122114660 cancer/testis antigen family 47, member A11 [Homo
sapiens]
Length = 288
Score = 38.1 bits (87), Expect = 0.038
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)
Query: 2 EELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVEL 61
E ++ E+ EE L +E E+PD E EEP A EATA + T S P K E
Sbjct: 206 EMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQ--EATAPEEVTKSQP--EKWDEEA 261
Query: 62 QELVMDEKNQELRWMEAARWVQ 83
Q+ +E+ ++ + +A V+
Sbjct: 262 QDAAGEEEKEQEKEKDAENKVK 283
>gi|6912430 isoprenylcysteine carboxyl methyltransferase [Homo
sapiens]
Length = 284
Score = 37.0 bits (84), Expect = 0.084
Identities = 26/72 (36%), Positives = 40/72 (55%), Gaps = 11/72 (15%)
Query: 748 GAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYM-GVTSLSGIQLF 806
G AA+ E R+S L L+G S+L P+L+R L G+ LY+ G+ +L
Sbjct: 3 GCAARAPPGSEARLS--LATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNAL------ 54
Query: 807 DRILLLFKPPKY 818
+LLL++PP+Y
Sbjct: 55 --LLLLYRPPRY 64
>gi|215272392 solute carrier family 18 (vesicular monoamine), member
1 isoform c [Homo sapiens]
Length = 472
Score = 35.4 bits (80), Expect = 0.24
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 13/83 (15%)
Query: 448 GILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAF 507
G+LFA LLV F GPL TN + Y + ++ GF ++ L ++ AF
Sbjct: 140 GVLFASKAVMQLLVNPFVGPL------------TNRIGYHIP-MFAGFVIMFLSTVMFAF 186
Query: 508 EGSFLVRFISRYTQEIFSFLISL 530
G++ + F++R Q I S S+
Sbjct: 187 SGTYTLLFVARTLQGIGSSFSSV 209
>gi|215272390 solute carrier family 18 (vesicular monoamine), member
1 isoform b [Homo sapiens]
Length = 493
Score = 35.4 bits (80), Expect = 0.24
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 13/83 (15%)
Query: 448 GILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAF 507
G+LFA LLV F GPL TN + Y + ++ GF ++ L ++ AF
Sbjct: 140 GVLFASKAVMQLLVNPFVGPL------------TNRIGYHIP-MFAGFVIMFLSTVMFAF 186
Query: 508 EGSFLVRFISRYTQEIFSFLISL 530
G++ + F++R Q I S S+
Sbjct: 187 SGTYTLLFVARTLQGIGSSFSSV 209
>gi|208879454 solute carrier family 18 (vesicular monoamine), member
1 isoform a [Homo sapiens]
Length = 525
Score = 35.4 bits (80), Expect = 0.24
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 13/83 (15%)
Query: 448 GILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAF 507
G+LFA LLV F GPL TN + Y + ++ GF ++ L ++ AF
Sbjct: 140 GVLFASKAVMQLLVNPFVGPL------------TNRIGYHIP-MFAGFVIMFLSTVMFAF 186
Query: 508 EGSFLVRFISRYTQEIFSFLISL 530
G++ + F++R Q I S S+
Sbjct: 187 SGTYTLLFVARTLQGIGSSFSSV 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,385,052
Number of Sequences: 37866
Number of extensions: 1574961
Number of successful extensions: 4610
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 4434
Number of HSP's gapped (non-prelim): 119
length of query: 911
length of database: 18,247,518
effective HSP length: 111
effective length of query: 800
effective length of database: 14,044,392
effective search space: 11235513600
effective search space used: 11235513600
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.