Guide to the Human Genome
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Search of human proteins with 4506597

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506597 ribosomal protein L12 [Homo sapiens]
         (165 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506597 ribosomal protein L12 [Homo sapiens]                       331   2e-91
gi|25306275 mitochondrial ribosomal protein L11 isoform c [Homo ...    32   0.33 
gi|7705618 mitochondrial ribosomal protein L11 isoform a [Homo s...    32   0.33 
gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens]     31   0.43 
gi|169790837 runt-related transcription factor 1 isoform AML1a [...    31   0.56 
gi|19923198 runt-related transcription factor 1 isoform AML1c [H...    31   0.56 
gi|49574546 runt-related transcription factor 1 isoform AML1b [H...    31   0.56 
gi|21450832 spindle and KT associated 1 [Homo sapiens]                 30   0.73 
gi|88014625 spindle and KT associated 1 [Homo sapiens]                 30   0.73 
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]        30   0.95 
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]         30   0.95 
gi|24308075 RAB11 family interacting protein 5 (class I) [Homo s...    28   2.8  
gi|56550073 peptidoglycan recognition protein-I-beta precursor [...    28   3.6  
gi|84043967 REV1-like isoform 2 [Homo sapiens]                         28   4.7  
gi|7706681 REV1-like isoform 1 [Homo sapiens]                          28   4.7  
gi|126116565 MYC binding protein 2 [Homo sapiens]                      28   4.7  
gi|208022687 GTPase regulator associated with the focal adhesion...    27   8.0  
gi|7662208 GTPase regulator associated with the focal adhesion k...    27   8.0  
gi|21687188 hypothetical protein LOC146325 [Homo sapiens]              27   8.0  

>gi|4506597 ribosomal protein L12 [Homo sapiens]
          Length = 165

 Score =  331 bits (849), Expect = 2e-91
 Identities = 165/165 (100%), Positives = 165/165 (100%)

Query: 1   MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITV 60
           MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITV
Sbjct: 1   MPPKFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLSPKKVGDDIAKATGDWKGLRITV 60

Query: 61  KLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRS 120
           KLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRS
Sbjct: 61  KLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRS 120

Query: 121 LARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS 165
           LARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS
Sbjct: 121 LARELSGTIKEILGTAQSVGCNVDGRHPHDIIDDINSGAVECPAS 165


>gi|25306275 mitochondrial ribosomal protein L11 isoform c [Homo
           sapiens]
          Length = 181

 Score = 31.6 bits (70), Expect = 0.33
 Identities = 29/122 (23%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 28  LAPKIGPLGLSPKKVGDDIAKATGDWK-GLRITVKLTIQ-NRQAQIEVVPSASALIIKAL 85
           L P +G  G+S  +   +  + T D K G+ +  K+ ++ +R  +I++     +  +KA 
Sbjct: 35  LGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAA 94

Query: 86  KEPPRDRKKQKNIKHSGNITFDEIVNIAR-QMRHRSLARE---LSGTIKEILGTAQSVGC 141
               +  + Q   + +G +T   +  IAR + +  + A +   LS  ++ I+G+A+S+G 
Sbjct: 95  AGIEKGAR-QTGKEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGI 153

Query: 142 NV 143
            V
Sbjct: 154 RV 155


>gi|7705618 mitochondrial ribosomal protein L11 isoform a [Homo
           sapiens]
          Length = 192

 Score = 31.6 bits (70), Expect = 0.33
 Identities = 29/122 (23%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 28  LAPKIGPLGLSPKKVGDDIAKATGDWK-GLRITVKLTIQ-NRQAQIEVVPSASALIIKAL 85
           L P +G  G+S  +   +  + T D K G+ +  K+ ++ +R  +I++     +  +KA 
Sbjct: 35  LGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAA 94

Query: 86  KEPPRDRKKQKNIKHSGNITFDEIVNIAR-QMRHRSLARE---LSGTIKEILGTAQSVGC 141
               +  + Q   + +G +T   +  IAR + +  + A +   LS  ++ I+G+A+S+G 
Sbjct: 95  AGIEKGAR-QTGKEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGI 153

Query: 142 NV 143
            V
Sbjct: 154 RV 155


>gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens]
          Length = 745

 Score = 31.2 bits (69), Expect = 0.43
 Identities = 30/127 (23%), Positives = 53/127 (41%), Gaps = 8/127 (6%)

Query: 35  LGLSPKKVGDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKK 94
           L  +  K   D+    G      I  K T ++R+ Q+E    +     K  K PP + K 
Sbjct: 432 LNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEWQKSKG---KTYKRPPMELKT 488

Query: 95  QKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQSVGCNVDGRHPHDIIDD 154
           ++ +    NI+F +  +I ++   +    ELS  I   L    ++   ++G  P + I +
Sbjct: 489 KRKVIKEMNISFWK--SIEKEEEEKKAQLELSSKINNTLTECLNL---IEGGVPSNEILN 543

Query: 155 INSGAVE 161
           I S   E
Sbjct: 544 ILSSIPE 550


>gi|169790837 runt-related transcription factor 1 isoform AML1a
           [Homo sapiens]
          Length = 250

 Score = 30.8 bits (68), Expect = 0.56
 Identities = 15/68 (22%), Positives = 33/68 (48%)

Query: 54  KGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIA 113
           +G   T+ +T+     Q+     A  + +   +EP R R+K  +    G+++F E ++  
Sbjct: 142 RGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSEL 201

Query: 114 RQMRHRSL 121
            Q+R  ++
Sbjct: 202 EQLRRTAM 209


>gi|19923198 runt-related transcription factor 1 isoform AML1c [Homo
           sapiens]
          Length = 480

 Score = 30.8 bits (68), Expect = 0.56
 Identities = 15/68 (22%), Positives = 33/68 (48%)

Query: 54  KGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIA 113
           +G   T+ +T+     Q+     A  + +   +EP R R+K  +    G+++F E ++  
Sbjct: 169 RGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSEL 228

Query: 114 RQMRHRSL 121
            Q+R  ++
Sbjct: 229 EQLRRTAM 236


>gi|49574546 runt-related transcription factor 1 isoform AML1b [Homo
           sapiens]
          Length = 453

 Score = 30.8 bits (68), Expect = 0.56
 Identities = 15/68 (22%), Positives = 33/68 (48%)

Query: 54  KGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIA 113
           +G   T+ +T+     Q+     A  + +   +EP R R+K  +    G+++F E ++  
Sbjct: 142 RGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSEL 201

Query: 114 RQMRHRSL 121
            Q+R  ++
Sbjct: 202 EQLRRTAM 209


>gi|21450832 spindle and KT associated 1 [Homo sapiens]
          Length = 255

 Score = 30.4 bits (67), Expect = 0.73
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 85  LKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEI 132
           +K+PP   K+Q++IK    IT DE   +   M+ R    +++  IKEI
Sbjct: 124 VKKPP---KEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEI 168


>gi|88014625 spindle and KT associated 1 [Homo sapiens]
          Length = 255

 Score = 30.4 bits (67), Expect = 0.73
 Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 3/48 (6%)

Query: 85  LKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEI 132
           +K+PP   K+Q++IK    IT DE   +   M+ R    +++  IKEI
Sbjct: 124 VKKPP---KEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEI 168


>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
          Length = 713

 Score = 30.0 bits (66), Expect = 0.95
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 4/45 (8%)

Query: 7   PNEIKVVYLRCTGGEVGATSALAPKIGPLGL----SPKKVGDDIA 47
           P E+  +  +C G E+G TS     + PL L    +PK+VGD IA
Sbjct: 199 PRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIA 243


>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
          Length = 724

 Score = 30.0 bits (66), Expect = 0.95
 Identities = 18/45 (40%), Positives = 25/45 (55%), Gaps = 4/45 (8%)

Query: 7   PNEIKVVYLRCTGGEVGATSALAPKIGPLGL----SPKKVGDDIA 47
           P E+  +  +C G E+G TS     + PL L    +PK+VGD IA
Sbjct: 206 PRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIA 250


>gi|24308075 RAB11 family interacting protein 5 (class I) [Homo
           sapiens]
          Length = 653

 Score = 28.5 bits (62), Expect = 2.8
 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 1/38 (2%)

Query: 21  EVGATSALAPKIGP-LGLSPKKVGDDIAKATGDWKGLR 57
           E+G  S+L  K GP LG SP        KA   W GLR
Sbjct: 476 ELGRRSSLGEKGGPILGASPHHSSSGEEKAKSSWFGLR 513


>gi|56550073 peptidoglycan recognition protein-I-beta precursor
           [Homo sapiens]
          Length = 373

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 19/85 (22%), Positives = 40/85 (47%), Gaps = 4/85 (4%)

Query: 78  SALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEILGTAQ 137
           SAL I+A  +   ++ + K +       F+ I     Q+  + L  ++S T+      A+
Sbjct: 9   SALGIQAWGDSSWNKTQAKQVSEGLQYLFENI----SQLTEKGLPTDVSTTVSRKAWGAE 64

Query: 138 SVGCNVDGRHPHDIIDDINSGAVEC 162
           +VGC++    P +++   +   +EC
Sbjct: 65  AVGCSIQLTTPVNVLVIHHVPGLEC 89


>gi|84043967 REV1-like isoform 2 [Homo sapiens]
          Length = 1250

 Score = 27.7 bits (60), Expect = 4.7
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 3/93 (3%)

Query: 4   KFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLS-PKKVGDDIAKATGDWKGLRITVKL 62
           K    E K V+      E+ + S     + P     P     + A+++G W GL   V  
Sbjct: 862 KSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTSPDTNKAESSGKWNGLHTPV-- 919

Query: 63  TIQNRQAQIEVVPSASALIIKALKEPPRDRKKQ 95
           ++Q+R      VPS S L    L+  P D ++Q
Sbjct: 920 SVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQ 952


>gi|7706681 REV1-like isoform 1 [Homo sapiens]
          Length = 1251

 Score = 27.7 bits (60), Expect = 4.7
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 3/93 (3%)

Query: 4   KFDPNEIKVVYLRCTGGEVGATSALAPKIGPLGLS-PKKVGDDIAKATGDWKGLRITVKL 62
           K    E K V+      E+ + S     + P     P     + A+++G W GL   V  
Sbjct: 863 KSTEEEHKEVFRAAVDLEISSASRTCTFLPPFPAHLPTSPDTNKAESSGKWNGLHTPV-- 920

Query: 63  TIQNRQAQIEVVPSASALIIKALKEPPRDRKKQ 95
           ++Q+R      VPS S L    L+  P D ++Q
Sbjct: 921 SVQSRLNLSIEVPSPSQLDQSVLEALPPDLREQ 953


>gi|126116565 MYC binding protein 2 [Homo sapiens]
          Length = 4640

 Score = 27.7 bits (60), Expect = 4.7
 Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)

Query: 74   VPSASALIIKALKEPPRDRKKQKNIKHSGNITFDEIVNIARQMRHRSLARELSGTIKEIL 133
            +P  S   +K   +PPR+R K  +     +    + + +   +R RS + +     K+  
Sbjct: 2812 LPQKSTAPVKTKLDPPRERSKSDSYTLDPDTLRKKKMPLTEPLRGRSTSPKPKSVPKD-- 2869

Query: 134  GTAQSVGCNVDGRHPHDIIDDINSGAVE-CPAS 165
             +  S G       PH + ++++S  VE C +S
Sbjct: 2870 -STDSPGSENRAPSPHVVQENLHSEVVEVCTSS 2901


>gi|208022687 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform b [Homo sapiens]
          Length = 759

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 3/51 (5%)

Query: 43  GDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRK 93
           G ++AK  GD+K     + ++IQN + + E   S    ++K +KE P + K
Sbjct: 214 GYELAKDFGDFK---TQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEHK 261


>gi|7662208 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform a [Homo sapiens]
          Length = 814

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 3/51 (5%)

Query: 43  GDDIAKATGDWKGLRITVKLTIQNRQAQIEVVPSASALIIKALKEPPRDRK 93
           G ++AK  GD+K     + ++IQN + + E   S    ++K +KE P + K
Sbjct: 214 GYELAKDFGDFK---TQLTISIQNTRNRFEGTRSEVESLMKKMKENPLEHK 261


>gi|21687188 hypothetical protein LOC146325 [Homo sapiens]
          Length = 571

 Score = 26.9 bits (58), Expect = 8.0
 Identities = 10/21 (47%), Positives = 16/21 (76%)

Query: 33  GPLGLSPKKVGDDIAKATGDW 53
           GP+  SP+ VG+D+ +A GD+
Sbjct: 395 GPVPGSPEHVGEDLTRALGDY 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,320,128
Number of Sequences: 37866
Number of extensions: 237829
Number of successful extensions: 654
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 646
Number of HSP's gapped (non-prelim): 20
length of query: 165
length of database: 18,247,518
effective HSP length: 94
effective length of query: 71
effective length of database: 14,688,114
effective search space: 1042856094
effective search space used: 1042856094
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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