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Search of human proteins with 4506391
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506391 RAD51 homolog C isoform 2 [Homo sapiens]
(135 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506391 RAD51 homolog C isoform 2 [Homo sapiens] 270 3e-73
gi|17402896 RAD51 homolog C isoform 1 [Homo sapiens] 265 6e-72
gi|46255039 RAD51-like 1 isoform 3 [Homo sapiens] 49 9e-07
gi|19924117 RAD51-like 1 isoform 2 [Homo sapiens] 49 9e-07
gi|10835029 RAD51-like 1 isoform 1 [Homo sapiens] 49 9e-07
gi|153946430 X-ray repair cross complementing protein 3 [Homo sa... 42 2e-04
gi|153946427 X-ray repair cross complementing protein 3 [Homo sa... 42 2e-04
gi|4885659 X-ray repair cross complementing protein 3 [Homo sapi... 42 2e-04
gi|19924133 RAD51 homolog protein isoform 1 [Homo sapiens] 35 0.014
gi|23238219 DMC1 dosage suppressor of mck1 homolog [Homo sapiens] 34 0.041
gi|217416415 RAD51-like 3 isoform 1 [Homo sapiens] 33 0.054
gi|217272816 RAD51-like 3 isoform 6 [Homo sapiens] 32 0.20
gi|166235180 tetratricopeptide repeat domain 22 isoform 1 [Homo ... 31 0.27
gi|154350220 DNA polymerase iota [Homo sapiens] 30 0.59
gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] 28 2.3
gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] 28 2.3
gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens] 28 2.9
gi|27501458 CTF18, chromosome transmission fidelity factor 18 ho... 27 5.0
gi|154275771 RAD51 homolog protein isoform 2 [Homo sapiens] 27 6.6
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens] 27 6.6
gi|122937257 thrombospondin, type I, domain containing 7B [Homo ... 26 8.6
>gi|4506391 RAD51 homolog C isoform 2 [Homo sapiens]
Length = 135
Score = 270 bits (689), Expect = 3e-73
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALET 60
MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALET
Sbjct: 1 MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALET 60
Query: 61 LQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKT 120
LQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKT
Sbjct: 61 LQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKT 120
Query: 121 TEICGAPGVGKTQLW 135
TEICGAPGVGKTQLW
Sbjct: 121 TEICGAPGVGKTQLW 135
>gi|17402896 RAD51 homolog C isoform 1 [Homo sapiens]
Length = 376
Score = 265 bits (678), Expect = 6e-72
Identities = 134/134 (100%), Positives = 134/134 (100%)
Query: 1 MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALET 60
MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALET
Sbjct: 1 MRGKTFRFEMQRDLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALET 60
Query: 61 LQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKT 120
LQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKT
Sbjct: 61 LQIIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKT 120
Query: 121 TEICGAPGVGKTQL 134
TEICGAPGVGKTQL
Sbjct: 121 TEICGAPGVGKTQL 134
>gi|46255039 RAD51-like 1 isoform 3 [Homo sapiens]
Length = 384
Score = 49.3 bits (116), Expect = 9e-07
Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Query: 34 TAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPRYAGTSESHKKCTALELLEQ 93
T ++ L + P EL K G+S E L ++ R C G
Sbjct: 26 TCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSA--------- 76
Query: 94 EHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQ 133
+ + F+ T SALD+ L GGV TEI G PG GKTQ
Sbjct: 77 DFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQ 116
>gi|19924117 RAD51-like 1 isoform 2 [Homo sapiens]
Length = 350
Score = 49.3 bits (116), Expect = 9e-07
Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Query: 34 TAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPRYAGTSESHKKCTALELLEQ 93
T ++ L + P EL K G+S E L ++ R C G
Sbjct: 26 TCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSA--------- 76
Query: 94 EHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQ 133
+ + F+ T SALD+ L GGV TEI G PG GKTQ
Sbjct: 77 DFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQ 116
>gi|10835029 RAD51-like 1 isoform 1 [Homo sapiens]
Length = 350
Score = 49.3 bits (116), Expect = 9e-07
Identities = 33/100 (33%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Query: 34 TAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPRYAGTSESHKKCTALELLEQ 93
T ++ L + P EL K G+S E L ++ R C G
Sbjct: 26 TCQDFLCLSPLELMKVTGLSYRGVHELLCMVSRACAPKMQTAYGIKAQRSA--------- 76
Query: 94 EHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQ 133
+ + F+ T SALD+ L GGV TEI G PG GKTQ
Sbjct: 77 DFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQ 116
>gi|153946430 X-ray repair cross complementing protein 3 [Homo
sapiens]
Length = 346
Score = 41.6 bits (96), Expect = 2e-04
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 15/126 (11%)
Query: 13 DLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNK 72
DL L+P + + A ++ +E+L +L + +S E L+ T
Sbjct: 2 DLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLR-------TAS 54
Query: 73 PRYAGTSESHKKCTALELLEQEH---TQGFIITF-CSALDDILGGGVPLMKTTEICGAPG 128
G+S TAL+L +Q+ TQ ++ C LD +L GG+PL TE+ G
Sbjct: 55 LHLRGSSI----LTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSS 110
Query: 129 VGKTQL 134
GKTQL
Sbjct: 111 AGKTQL 116
>gi|153946427 X-ray repair cross complementing protein 3 [Homo
sapiens]
Length = 346
Score = 41.6 bits (96), Expect = 2e-04
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 15/126 (11%)
Query: 13 DLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNK 72
DL L+P + + A ++ +E+L +L + +S E L+ T
Sbjct: 2 DLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLR-------TAS 54
Query: 73 PRYAGTSESHKKCTALELLEQEH---TQGFIITF-CSALDDILGGGVPLMKTTEICGAPG 128
G+S TAL+L +Q+ TQ ++ C LD +L GG+PL TE+ G
Sbjct: 55 LHLRGSSI----LTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSS 110
Query: 129 VGKTQL 134
GKTQL
Sbjct: 111 AGKTQL 116
>gi|4885659 X-ray repair cross complementing protein 3 [Homo
sapiens]
Length = 346
Score = 41.6 bits (96), Expect = 2e-04
Identities = 37/126 (29%), Positives = 57/126 (45%), Gaps = 15/126 (11%)
Query: 13 DLVSFPLSPAVRVKLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNK 72
DL L+P + + A ++ +E+L +L + +S E L+ T
Sbjct: 2 DLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLR-------TAS 54
Query: 73 PRYAGTSESHKKCTALELLEQEH---TQGFIITF-CSALDDILGGGVPLMKTTEICGAPG 128
G+S TAL+L +Q+ TQ ++ C LD +L GG+PL TE+ G
Sbjct: 55 LHLRGSSI----LTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSS 110
Query: 129 VGKTQL 134
GKTQL
Sbjct: 111 AGKTQL 116
>gi|19924133 RAD51 homolog protein isoform 1 [Homo sapiens]
Length = 339
Score = 35.4 bits (80), Expect = 0.014
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 26 KLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPR-YAGTSESHKK 84
KL AGF T E + EL GIS+A+A + L E P + +E H++
Sbjct: 40 KLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILA----EAAKLVPMGFTTATEFHQR 95
Query: 85 CTALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQL 134
+ E+++ I T LD +L GG+ TE+ G GKTQ+
Sbjct: 96 RS--EIIQ-------ITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQI 136
>gi|23238219 DMC1 dosage suppressor of mck1 homolog [Homo sapiens]
Length = 340
Score = 33.9 bits (76), Expect = 0.041
Identities = 36/125 (28%), Positives = 52/125 (41%), Gaps = 22/125 (17%)
Query: 31 GFQTAEELLEVKPSELSKEVGISKAE----------ALETLQIIRRECLTN-----KPRY 75
GFQ EE L + +L ++ GI+ A+ ++ +Q+ R L N + +
Sbjct: 12 GFQDEEESL-FQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKV 70
Query: 76 AGTSESHKKC------TALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGV 129
E+ K TA E E+ I T D +LGGG+ M TE G
Sbjct: 71 DKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRT 130
Query: 130 GKTQL 134
GKTQL
Sbjct: 131 GKTQL 135
>gi|217416415 RAD51-like 3 isoform 1 [Homo sapiens]
Length = 328
Score = 33.5 bits (75), Expect = 0.054
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 27 LVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTNKPRYAGTSESHKKCT 86
L S +T +L+ E++++ G+S + +++ + A E K T
Sbjct: 20 LRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQFSAFPVNGADLYEELKTST 79
Query: 87 ALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTEICGAPGVGKTQL 134
A+ + T +LD +L G+ + TEI G PG GKTQ+
Sbjct: 80 AI-----------LSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQV 116
>gi|217272816 RAD51-like 3 isoform 6 [Homo sapiens]
Length = 348
Score = 31.6 bits (70), Expect = 0.20
Identities = 15/30 (50%), Positives = 19/30 (63%)
Query: 105 SALDDILGGGVPLMKTTEICGAPGVGKTQL 134
S LD +L G+ + TEI G PG GKTQ+
Sbjct: 107 SRLDKLLDAGLYTGEVTEIVGGPGSGKTQV 136
>gi|166235180 tetratricopeptide repeat domain 22 isoform 1 [Homo
sapiens]
Length = 569
Score = 31.2 bits (69), Expect = 0.27
Identities = 23/76 (30%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 31 GFQTAEELLEVKPSELSKE-VGISKA------EALETLQIIRRECLTNKPRYAGTSESHK 83
G +ELL V + L++ V ++KA L LQ++R +CL K A + K
Sbjct: 397 GVDAVQELLAVDEAALNQALVFLAKAGESELGATLPELQLLRGKCLRIKGEDANAAACFK 456
Query: 84 KCTALELLEQEHTQGF 99
+ L+ HT GF
Sbjct: 457 RAVELDDAGSSHTDGF 472
>gi|154350220 DNA polymerase iota [Homo sapiens]
Length = 740
Score = 30.0 bits (66), Expect = 0.59
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 27 LVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRRE---CLTNKPRYAGTSESHK 83
L + G + +L P L KE+GIS A+ ++ L L+ P+ +S K
Sbjct: 275 LEALGINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFK 334
Query: 84 KCTA 87
KC++
Sbjct: 335 KCSS 338
>gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens]
Length = 698
Score = 28.1 bits (61), Expect = 2.3
Identities = 11/22 (50%), Positives = 17/22 (77%)
Query: 46 LSKEVGISKAEALETLQIIRRE 67
+SKEVG+ K EA++TL ++ E
Sbjct: 668 ISKEVGVEKLEAMKTLATLKEE 689
>gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens]
Length = 725
Score = 28.1 bits (61), Expect = 2.3
Identities = 11/22 (50%), Positives = 17/22 (77%)
Query: 46 LSKEVGISKAEALETLQIIRRE 67
+SKEVG+ K EA++TL ++ E
Sbjct: 695 ISKEVGVEKLEAMKTLATLKEE 716
>gi|4505121 methyl-CpG binding domain protein 4 [Homo sapiens]
Length = 580
Score = 27.7 bits (60), Expect = 2.9
Identities = 24/75 (32%), Positives = 32/75 (42%), Gaps = 7/75 (9%)
Query: 35 AEELLEVKPSELSKEVGISKAEAL-ETLQIIRRECLTNKPRYAGTSESHKKCTALELLEQ 93
AE + S+L + V IS A A ETL + E K + S C+ +
Sbjct: 273 AESEPVAQKSQLDRTVCISDAGACGETLSVTSEENSLVKKKERSLSSGSNFCS------E 326
Query: 94 EHTQGFIITFCSALD 108
+ T G I FCSA D
Sbjct: 327 QKTSGIINKFCSAKD 341
>gi|27501458 CTF18, chromosome transmission fidelity factor 18
homolog [Homo sapiens]
Length = 975
Score = 26.9 bits (58), Expect = 5.0
Identities = 13/33 (39%), Positives = 19/33 (57%), Gaps = 5/33 (15%)
Query: 107 LDDILGGGV-----PLMKTTEICGAPGVGKTQL 134
L+++L G+ P K +CG PG+GKT L
Sbjct: 351 LEEMLEAGLDPSQRPKQKVALLCGPPGLGKTTL 383
>gi|154275771 RAD51 homolog protein isoform 2 [Homo sapiens]
Length = 242
Score = 26.6 bits (57), Expect = 6.6
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 26 KLVSAGFQTAEELLEVKPSELSKEVGISKAEALETLQIIRR 66
KL AGF T E + EL GIS+A+A + L + R
Sbjct: 40 KLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILVMAER 80
>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
Length = 778
Score = 26.6 bits (57), Expect = 6.6
Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 10/73 (13%)
Query: 33 QTAEELLEVKPSELSKEVGISKAEALETLQIIRRECLTN----------KPRYAGTSESH 82
+T L + + + K+ I + +ALE + I + +N P YAG ES
Sbjct: 690 KTLSILSKPQTEKTQKKSAIPRQKALEYAKTIPKPKPSNLTHQASKEQKNPTYAGKEESL 749
Query: 83 KKCTALELLEQEH 95
+ + LE+L+ H
Sbjct: 750 PEISLLEILQNRH 762
>gi|122937257 thrombospondin, type I, domain containing 7B [Homo
sapiens]
Length = 1577
Score = 26.2 bits (56), Expect = 8.6
Identities = 19/67 (28%), Positives = 29/67 (43%), Gaps = 9/67 (13%)
Query: 63 IIRRECLTNKPRYAGTSESHKKCTALELLEQEHTQGFIITFCSALDDILGGGVPLMKTTE 122
I+ E L PRY+ + K+C LLEQ+ + + GGG+ +T E
Sbjct: 358 IVEGELLQQCPRYSWRTSEWKECQVSLLLEQQDPHWHV------TGPVCGGGI---QTRE 408
Query: 123 ICGAPGV 129
+ A V
Sbjct: 409 VYCAQSV 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,929,037
Number of Sequences: 37866
Number of extensions: 182854
Number of successful extensions: 563
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 542
Number of HSP's gapped (non-prelim): 21
length of query: 135
length of database: 18,247,518
effective HSP length: 91
effective length of query: 44
effective length of database: 14,801,712
effective search space: 651275328
effective search space used: 651275328
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.