Search of human proteins with 4505823

Search of human proteins with 4505823

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505823 pirin [Homo sapiens]
         (290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|66363697 pirin [Homo sapiens]                                      598   e-171
gi|4505823 pirin [Homo sapiens]                                       598   e-171
gi|38348408 hypothetical protein LOC375444 [Homo sapiens]              32   0.50 
gi|34740331 otoferlin isoform a [Homo sapiens]                         31   1.5  
gi|208431769 basophilic leukemia expressed protein BLES03 isofor...    30   2.5  
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ...    30   3.2  
gi|39995082 NOL1/NOP2/Sun domain family, member 2 [Homo sapiens]       29   4.2  
gi|28558984 thyroid peroxidase isoform b [Homo sapiens]                29   5.5  
gi|208431771 basophilic leukemia expressed protein BLES03 isofor...    29   5.5  
gi|7657301 kelch domain containing 2 [Homo sapiens]                    28   7.2  
gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isof...    28   9.4  
gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isof...    28   9.4  
gi|150170696 hypothetical protein LOC389073 [Homo sapiens]             28   9.4  

>gi|66363697 pirin [Homo sapiens]
          Length = 290

 Score =  598 bits (1543), Expect = e-171
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRG 60
           MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRG
Sbjct: 1   MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRG 60

Query: 61  FETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNL 120
           FETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNL
Sbjct: 61  FETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNL 120

Query: 121 RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA 180
           RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA
Sbjct: 121 RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA 180

Query: 181 KHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVL 240
           KHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVL
Sbjct: 181 KHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVL 240

Query: 241 IAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN 290
           IAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN
Sbjct: 241 IAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN 290


>gi|4505823 pirin [Homo sapiens]
          Length = 290

 Score =  598 bits (1543), Expect = e-171
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 1   MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRG 60
           MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRG
Sbjct: 1   MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRG 60

Query: 61  FETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNL 120
           FETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNL
Sbjct: 61  FETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNL 120

Query: 121 RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA 180
           RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA
Sbjct: 121 RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA 180

Query: 181 KHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVL 240
           KHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVL
Sbjct: 181 KHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVL 240

Query: 241 IAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN 290
           IAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN
Sbjct: 241 IAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN 290


>gi|38348408 hypothetical protein LOC375444 [Homo sapiens]
          Length = 638

 Score = 32.3 bits (72), Expect = 0.50
 Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 14/70 (20%)

Query: 219 VLGEGDSVQVENKD-------PKRSHFVL-----IAGEPLREP--VIQHGPFVMNTNEEI 264
           +L E DSVQV+  D       P  S F+      ++  PL +P  + Q   FV++T  E 
Sbjct: 8   ILYEDDSVQVQYVDGSTLQLSPCGSEFLFEKSPPVSAHPLEQPERIRQRTHFVISTYREQ 67

Query: 265 SQAILDFRNA 274
            Q  LDFRN+
Sbjct: 68  LQRALDFRNS 77


>gi|34740331 otoferlin isoform a [Homo sapiens]
          Length = 1997

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 9/76 (11%)

Query: 159 IKSKVYTRTPTLYLDFKLDPGAKHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPH--- 215
           I SK   R+ TL   FK+D G  +SQP         +     +   PDD    ++ +   
Sbjct: 322 IHSKNLLRSGTLVGSFKMDVGTVYSQP------EHQFHHKWAILSDPDDISSGLKGYVKC 375

Query: 216 HTAVLGEGDSVQVENK 231
             AV+G+GD+++  +K
Sbjct: 376 DVAVVGKGDNIKTPHK 391


>gi|208431769 basophilic leukemia expressed protein BLES03 isoform 2
           [Homo sapiens]
          Length = 292

 Score = 30.0 bits (66), Expect = 2.5
 Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 24/113 (21%)

Query: 96  GRGILHAEMPCSEEPAHGLQLWVNLRSSE-KMVEPQYQELKSEEIPKPSKDGVTVAVISG 154
           GRG   AE       A G   W  +  SE + +EP  +EL+ E  P   +DG T   ++ 
Sbjct: 13  GRGGGGAEPRQERSRARG---WAGVERSEGRRMEPG-EELEEEGSPGGREDGFTAEHLAA 68

Query: 155 EALGIKSKVY-----TRTPTLYLDFKL------------DPGAKHSQPIPKGW 190
           EA+      +       TP   LD  L            DPG+ +S+P+  GW
Sbjct: 69  EAMAADMDPWLVFDARTTPATELDAWLAKYPPSQVTRYGDPGSPNSEPV--GW 119


>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
           [Homo sapiens]
          Length = 1484

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 2/69 (2%)

Query: 207 DAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVLIAGEPLREPVIQHGPFVMNTNEEISQ 266
           DA +K + HH +V+   + V +   DPK    +    + + +  IQ   F  +T++E   
Sbjct: 52  DAHEKDDFHHLSVVPRVELVAMNETDPK--SIITRICDLMSDRKIQGVVFADDTDQEAIA 109

Query: 267 AILDFRNAK 275
            ILDF +A+
Sbjct: 110 QILDFISAQ 118


>gi|39995082 NOL1/NOP2/Sun domain family, member 2 [Homo sapiens]
          Length = 767

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 46/201 (22%), Positives = 74/201 (36%), Gaps = 42/201 (20%)

Query: 112 HGLQLWVNLRSSEKMVE------------PQYQELKSEEIPKPSKDGVTVAVISGEALGI 159
           HGLQL +  R +E++ E            P   E     + + S+  + +A +S E  G+
Sbjct: 296 HGLQLRIATRGAEQLAEGGRMVYSTCSLNPIEDEAVIASLLEKSEGALELADVSNELPGL 355

Query: 160 K-------SKVYTRTPTLYLDFKLDPGAKHSQPIPKGWTSFIYTISGDVYIGPDDAQQKI 212
           K        KV T+    + D+   P ++H+Q  P   T F       +     +   +I
Sbjct: 356 KWMPGITQWKVMTKDGQWFTDWDAVPHSRHTQIRP---TMFPPKDPEKLQAMHLERCLRI 412

Query: 213 EPHH-------TAVLGEGDSVQVENKDPK-------------RSHFVLIAGEPLREPVIQ 252
            PHH        AVL +  S+    + PK              S   L  G+P     ++
Sbjct: 413 LPHHQNTGGFFVAVLVKKSSMPWNKRQPKLQGKSAETRESTQLSPADLTEGKPTDPSKLE 472

Query: 253 HGPFVMNTNEEISQAILDFRN 273
              F    + EI+ A  D  N
Sbjct: 473 SPSFTGTGDTEIAHATEDLEN 493


>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
          Length = 876

 Score = 28.9 bits (63), Expect = 5.5
 Identities = 19/73 (26%), Positives = 29/73 (39%), Gaps = 8/73 (10%)

Query: 53  FPDHP-------HRGFETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMP 105
           F +HP       H+ F +   LL GG     +FCG      P DL    A R +    + 
Sbjct: 508 FQEHPDLPGLWLHQAFFSPWTLLRGGYNEWREFCGLPRLETPADLSTAIASRSVADKILD 567

Query: 106 CSEEPAHGLQLWV 118
             + P   + +W+
Sbjct: 568 LYKHP-DNIDVWL 579


>gi|208431771 basophilic leukemia expressed protein BLES03 isoform 1
           [Homo sapiens]
          Length = 293

 Score = 28.9 bits (63), Expect = 5.5
 Identities = 33/114 (28%), Positives = 46/114 (40%), Gaps = 25/114 (21%)

Query: 96  GRGILHAEMPCSEEPAHGLQLWVNLRSSE--KMVEPQYQELKSEEIPKPSKDGVTVAVIS 153
           GRG   AE       A G   W  +  SE    +EP  +EL+ E  P   +DG T   ++
Sbjct: 13  GRGGGGAEPRQERSRARG---WAGVERSEGRSRMEPG-EELEEEGSPGGREDGFTAEHLA 68

Query: 154 GEALGIKSKVY-----TRTPTLYLDFKL------------DPGAKHSQPIPKGW 190
            EA+      +       TP   LD  L            DPG+ +S+P+  GW
Sbjct: 69  AEAMAADMDPWLVFDARTTPATELDAWLAKYPPSQVTRYGDPGSPNSEPV--GW 120


>gi|7657301 kelch domain containing 2 [Homo sapiens]
          Length = 406

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 16/82 (19%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 121 RSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGA 180
           RS+++++  Q++ +  + IP  SKD + V V   + +      Y     +   F+ D  +
Sbjct: 124 RSTDRVL--QWERIDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETS 181

Query: 181 KHSQPIPKGWTSFIYTISGDVY 202
             +   P+GW   ++ +  + +
Sbjct: 182 FWNSSHPRGWNDHVHILDTETF 203


>gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isoform
           a [Homo sapiens]
          Length = 534

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 8/27 (29%), Positives = 15/27 (55%)

Query: 99  ILHAEMPCSEEPAHGLQLWVNLRSSEK 125
           I+   +PCS+ P   ++ W+N    E+
Sbjct: 210 IISDGVPCSQNPTEAIEAWINFNKEER 236


>gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isoform
           b [Homo sapiens]
          Length = 518

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 8/27 (29%), Positives = 15/27 (55%)

Query: 99  ILHAEMPCSEEPAHGLQLWVNLRSSEK 125
           I+   +PCS+ P   ++ W+N    E+
Sbjct: 194 IISDGVPCSQNPTEAIEAWINFNKEER 220


>gi|150170696 hypothetical protein LOC389073 [Homo sapiens]
          Length = 193

 Score = 28.1 bits (61), Expect = 9.4
 Identities = 14/51 (27%), Positives = 21/51 (41%)

Query: 90  LQWMTAGRGILHAEMPCSEEPAHGLQLWVNLRSSEKMVEPQYQELKSEEIP 140
           LQW+     +   E    + P HG  ++ N R  E M+   Y  +    IP
Sbjct: 52  LQWLDPSEDLTWLEWEELKIPLHGRPIYPNRREREAMILSSYAGILMNSIP 102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,807,489
Number of Sequences: 37866
Number of extensions: 660922
Number of successful extensions: 910
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 905
Number of HSP's gapped (non-prelim): 13
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.