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Search of human proteins with 4505819
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II,
beta [Homo sapiens]
(416 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b... 843 0.0
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a... 645 0.0
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,... 535 e-152
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,... 535 e-152
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,... 493 e-139
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,... 463 e-130
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be... 180 2e-45
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 170 2e-42
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 170 2e-42
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al... 170 2e-42
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g... 167 2e-41
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 154 1e-37
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is... 103 4e-22
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso... 60 3e-09
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 57 3e-08
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 33 0.37
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 33 0.37
gi|188536080 4-aminobutyrate aminotransferase precursor [Homo sa... 33 0.62
gi|38679950 4-aminobutyrate aminotransferase precursor [Homo sap... 33 0.62
gi|38679946 4-aminobutyrate aminotransferase precursor [Homo sap... 33 0.62
gi|7661878 kinesin family member 14 [Homo sapiens] 33 0.62
gi|225735631 mesoderm induction early response 1 isoform g [Homo... 32 0.81
gi|225735617 mesoderm induction early response 1 isoform h [Homo... 32 0.81
gi|225735615 mesoderm induction early response 1 isoform a [Homo... 32 0.81
gi|118130872 mesoderm induction early response 1 isoform f [Homo... 32 0.81
gi|225735612 mesoderm induction early response 1 isoform e [Homo... 32 0.81
gi|225735610 mesoderm induction early response 1 isoform d [Homo... 32 0.81
gi|118130815 mesoderm induction early response 1 isoform c [Homo... 32 0.81
gi|225735607 mesoderm induction early response 1 isoform b [Homo... 32 0.81
gi|225735605 mesoderm induction early response 1 isoform a [Homo... 32 0.81
>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
[Homo sapiens]
Length = 416
Score = 843 bits (2177), Expect = 0.0
Identities = 416/416 (100%), Positives = 416/416 (100%)
Query: 1 MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNV 60
MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNV
Sbjct: 1 MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNV 60
Query: 61 PVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNS 120
PVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNS
Sbjct: 61 PVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNS 120
Query: 121 VTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLL 180
VTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLL
Sbjct: 121 VTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLL 180
Query: 181 PQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKD 240
PQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKD
Sbjct: 181 PQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKD 240
Query: 241 NDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE 300
NDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE
Sbjct: 241 NDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEE 300
Query: 301 RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKK 360
RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKK
Sbjct: 301 RAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKK 360
Query: 361 EVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT 416
EVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT
Sbjct: 361 EVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT 416
>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
alpha [Homo sapiens]
Length = 406
Score = 645 bits (1665), Expect = 0.0
Identities = 314/399 (78%), Positives = 357/399 (89%), Gaps = 5/399 (1%)
Query: 18 ASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKI 77
ASKTKTKKKHFV QKVKLFRAS+P+LSVLMWGVNH+INELS+V +PVMLMPDDFKAYSKI
Sbjct: 13 ASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKI 72
Query: 78 KVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGT 137
KVDNHLFNKEN+PS FKFKEYCPMVFRNLRERFGIDDQD+QNS+TRSAP+ +DSQ R G
Sbjct: 73 KVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGA 132
Query: 138 RFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETY 197
RF T+YD+R++IKT++SEDVAEMHNILKKYHQ+IVECHG TLLPQFLGMYRL VDGVE Y
Sbjct: 133 RFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIY 192
Query: 198 MVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESK 257
++VTRNVFSHRL+V+RKYDLKGSTVAREASDKEKAK+LPT KDNDF+NEGQK+++ + +K
Sbjct: 193 VIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNK 252
Query: 258 KNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLL 317
K FLEKLK+DVEFLAQLK+MDYSLLVGIHDV+RAEQEE+E EE +EE E+DG
Sbjct: 253 KVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTH---- 308
Query: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
GTPPDSPGN L+ PGEFDP++DVY +K HE+SP+KEVYFMAIIDILT YD K
Sbjct: 309 -PVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
Query: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT 416
KKAAHAAKTVKHGAGAEISTVNPEQYSKRF +F+ +ILT
Sbjct: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT 406
>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 535 bits (1379), Expect = e-152
Identities = 267/397 (67%), Positives = 324/397 (81%), Gaps = 6/397 (1%)
Query: 21 TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80
+KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIKV+
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
Query: 81 NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140
NHLF++ENLPS FKFKEYCP VFRNLR+RFGIDDQDY S+TR+ P S+S+G G RFL
Sbjct: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFL 142
Query: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200
+YDR VIK VSSED+A+MH+ L YHQ+IV+CHGNTLLPQFLGMYR++VD ++YM+V
Sbjct: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
Query: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260
RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
Query: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317
LEKLKRDVEFL QLKIMDYSLL+GIHD+ R + E E R ++ E + D + G L+
Sbjct: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
Query: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
SYGT P+ G + R GPGEF+ +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
Query: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414
KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 535 bits (1379), Expect = e-152
Identities = 267/397 (67%), Positives = 324/397 (81%), Gaps = 6/397 (1%)
Query: 21 TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80
+KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIKV+
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
Query: 81 NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140
NHLF++ENLPS FKFKEYCP VFRNLR+RFGIDDQDY S+TR+ P S+S+G G RFL
Sbjct: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFL 142
Query: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200
+YDR VIK VSSED+A+MH+ L YHQ+IV+CHGNTLLPQFLGMYR++VD ++YM+V
Sbjct: 143 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 202
Query: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260
RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 203 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 262
Query: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317
LEKLKRDVEFL QLKIMDYSLL+GIHD+ R + E E R ++ E + D + G L+
Sbjct: 263 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 322
Query: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
SYGT P+ G + R GPGEF+ +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 323 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 382
Query: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414
KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 383 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 419
>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform b [Homo sapiens]
Length = 403
Score = 493 bits (1270), Expect = e-139
Identities = 253/397 (63%), Positives = 307/397 (77%), Gaps = 24/397 (6%)
Query: 21 TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80
+KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIK
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIK-- 83
Query: 81 NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140
EYCP VFRNLR+RFGIDDQDY S+TR+ P S+S+G G RFL
Sbjct: 84 ----------------EYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFL 124
Query: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200
+YDR VIK VSSED+A+MH+ L YHQ+IV+CHGNTLLPQFLGMYR++VD ++YM+V
Sbjct: 125 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 184
Query: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260
RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 185 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 244
Query: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317
LEKLKRDVEFL QLKIMDYSLL+GIHD+ R + E E R ++ E + D + G L+
Sbjct: 245 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 304
Query: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
SYGT P+ G + R GPGEF+ +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 305 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 364
Query: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414
KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 365 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 401
>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform c [Homo sapiens]
Length = 373
Score = 463 bits (1192), Expect = e-130
Identities = 238/397 (59%), Positives = 287/397 (72%), Gaps = 54/397 (13%)
Query: 21 TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80
+KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIKV+
Sbjct: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIKVN 85
Query: 81 NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140
NHLF++ENLPS FKFKEYCP VFRNLR+RFGIDDQDY
Sbjct: 86 NHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQDYL---------------------- 123
Query: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200
+IV+CHGNTLLPQFLGMYR++VD ++YM+V
Sbjct: 124 -----------------------------YIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 154
Query: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260
RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 155 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 214
Query: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317
LEKLKRDVEFL QLKIMDYSLL+GIHD+ R + E E R ++ E + D + G L+
Sbjct: 215 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 274
Query: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
SYGT P+ G + R GPGEF+ +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 275 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 334
Query: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414
KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 335 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 371
>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
isoform 2 [Homo sapiens]
Length = 540
Score = 180 bits (457), Expect = 2e-45
Identities = 135/406 (33%), Positives = 198/406 (48%), Gaps = 29/406 (7%)
Query: 14 APLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKA 73
AP ++ KT KK AS I + G+ +T+ L++ P +LM D +
Sbjct: 11 APGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVV 60
Query: 74 YSKI--KVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDS 131
S ++L + P F+FK Y P+ FR RE FGI DY S+ I +
Sbjct: 61 ESVFLPSEGSNLTPAHHYPD-FRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSN 119
Query: 132 QGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTV 191
G G+ F T D F+IKTV ++ + +L Y+ + + + TLLP+F G+Y +
Sbjct: 120 PGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCMQS 178
Query: 192 DGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKL 250
G+ +VV NV + +H YDLKGST R AS KE+ K PTFKD DFL + + L
Sbjct: 179 GGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGL 238
Query: 251 HVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND 310
+ E+ ++ L+RD L KIMDYSLL+GIH +D + +E+ E E + +
Sbjct: 239 YFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEK-EEETPQNVPDAKRT 297
Query: 311 GVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYA---MKSHESSPKKEVYFMAI 367
G+ L Y T +S + P G G + D KSH +K + FM I
Sbjct: 298 GMQKVL---YSTAMES----IQGPGKSGDGIITENPDTMGGIPAKSHRG--EKLLLFMGI 348
Query: 368 IDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSN 413
IDIL Y KK H+ K + + G +S P Y+ RF +FM++
Sbjct: 349 IDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 1 [Homo sapiens]
Length = 562
Score = 170 bits (431), Expect = 2e-42
Identities = 125/383 (32%), Positives = 185/383 (48%), Gaps = 25/383 (6%)
Query: 39 SEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKE--NLP-----S 91
S + + G+ HT+ LS P +LM D + V++ F E NL +
Sbjct: 82 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 135
Query: 92 RFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKT 151
F+FK Y P+ FR RE FGI DY S+ I S G G+ F + D F+IKT
Sbjct: 136 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 195
Query: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTV 211
V ++ + +L Y+ + + + TLLP+F G+Y + G +VV N+ + +
Sbjct: 196 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 254
Query: 212 HRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKLHVGEESKKNFLEKLKRDVEF 270
H KYDLKGST R AS KE+ K LPTFKD DFL + L + + + L+RD
Sbjct: 255 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 314
Query: 271 LAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNL 330
L KIMDYSLL+ IH++D A++E + +E + + Y T +S +
Sbjct: 315 LQSFKIMDYSLLMSIHNIDHAQREPLS----SETQYSVDTRRPAPQKALYSTAMES---I 367
Query: 331 LSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHG 390
R G E D + + + S ++ + ++ IIDIL Y KK H+ K + H
Sbjct: 368 QGEARRGGTMETDDHMG--GIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHD 425
Query: 391 AGAEISTVNPEQYSKRFNEFMSN 413
G +S P Y++RF FM N
Sbjct: 426 -GDTVSVHRPGFYAERFQRFMCN 447
>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 4 [Homo sapiens]
Length = 500
Score = 170 bits (431), Expect = 2e-42
Identities = 125/383 (32%), Positives = 185/383 (48%), Gaps = 25/383 (6%)
Query: 39 SEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKE--NLP-----S 91
S + + G+ HT+ LS P +LM D + V++ F E NL +
Sbjct: 69 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 122
Query: 92 RFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKT 151
F+FK Y P+ FR RE FGI DY S+ I S G G+ F + D F+IKT
Sbjct: 123 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 182
Query: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTV 211
V ++ + +L Y+ + + + TLLP+F G+Y + G +VV N+ + +
Sbjct: 183 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 241
Query: 212 HRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKLHVGEESKKNFLEKLKRDVEF 270
H KYDLKGST R AS KE+ K LPTFKD DFL + L + + + L+RD
Sbjct: 242 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 301
Query: 271 LAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNL 330
L KIMDYSLL+ IH++D A++E + +E + + Y T +S +
Sbjct: 302 LQSFKIMDYSLLMSIHNIDHAQREPLS----SETQYSVDTRRPAPQKALYSTAMES---I 354
Query: 331 LSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHG 390
R G E D + + + S ++ + ++ IIDIL Y KK H+ K + H
Sbjct: 355 QGEARRGGTMETDDHMG--GIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHD 412
Query: 391 AGAEISTVNPEQYSKRFNEFMSN 413
G +S P Y++RF FM N
Sbjct: 413 -GDTVSVHRPGFYAERFQRFMCN 434
>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
isoform 2 [Homo sapiens]
Length = 549
Score = 170 bits (431), Expect = 2e-42
Identities = 125/383 (32%), Positives = 185/383 (48%), Gaps = 25/383 (6%)
Query: 39 SEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKE--NLP-----S 91
S + + G+ HT+ LS P +LM D + V++ F E NL +
Sbjct: 69 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 122
Query: 92 RFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKT 151
F+FK Y P+ FR RE FGI DY S+ I S G G+ F + D F+IKT
Sbjct: 123 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 182
Query: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTV 211
V ++ + +L Y+ + + + TLLP+F G+Y + G +VV N+ + +
Sbjct: 183 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 241
Query: 212 HRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKLHVGEESKKNFLEKLKRDVEF 270
H KYDLKGST R AS KE+ K LPTFKD DFL + L + + + L+RD
Sbjct: 242 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 301
Query: 271 LAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNL 330
L KIMDYSLL+ IH++D A++E + +E + + Y T +S +
Sbjct: 302 LQSFKIMDYSLLMSIHNIDHAQREPLS----SETQYSVDTRRPAPQKALYSTAMES---I 354
Query: 331 LSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHG 390
R G E D + + + S ++ + ++ IIDIL Y KK H+ K + H
Sbjct: 355 QGEARRGGTMETDDHMG--GIPARNSKGERLLLYIGIIDILQSYRFVKKLEHSWKALVHD 412
Query: 391 AGAEISTVNPEQYSKRFNEFMSN 413
G +S P Y++RF FM N
Sbjct: 413 -GDTVSVHRPGFYAERFQRFMCN 434
>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
gamma [Homo sapiens]
Length = 668
Score = 167 bits (423), Expect = 2e-41
Identities = 124/384 (32%), Positives = 187/384 (48%), Gaps = 27/384 (7%)
Query: 39 SEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKEN---LPSR--- 92
S + + G+ +T+ LS+ P +LM D + V++ F E P+
Sbjct: 76 SSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHFQ 129
Query: 93 -FKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKT 151
F+FK Y P+ FR RE FGI DY S+ I + G G+ F T D F+IKT
Sbjct: 130 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKT 189
Query: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTV 211
V ++ + +L Y+ + + + TLLP+F G+Y + G +VV N+ + +
Sbjct: 190 VMHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKM 248
Query: 212 HRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKLHVGEESKKNFLEKLKRDVEF 270
H K+DLKGST R AS KEK K PT+KD DF+ + + L + ++ ++ L+RD
Sbjct: 249 HLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLV 308
Query: 271 LAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNL 330
L KIMDYSLL+G+H++D+ E+E + A+ E VG L Y T +
Sbjct: 309 LESFKIMDYSLLLGVHNIDQHERERQ--AQGAQSTSDEKRPVGQKAL--YSTAME----- 359
Query: 331 LSFPRFFGPGEFDPSVDVY-AMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKH 389
S GE S D + + ++ + + IIDIL Y KK H K + H
Sbjct: 360 -SIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVH 418
Query: 390 GAGAEISTVNPEQYSKRFNEFMSN 413
G +S P Y++RF +FMSN
Sbjct: 419 D-GDTVSVHRPSFYAERFFKFMSN 441
>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 3 [Homo sapiens]
Length = 522
Score = 154 bits (390), Expect = 1e-37
Identities = 118/393 (30%), Positives = 173/393 (44%), Gaps = 73/393 (18%)
Query: 39 SEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKE--NLP-----S 91
S + + G+ HT+ LS P +LM D + V++ F E NL +
Sbjct: 70 SSALKGAIQLGITHTVGSLSTKPERDVLMQDFYV------VESIFFPSEGSNLTPAHHYN 123
Query: 92 RFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKT 151
F+FK Y P+ FR RE FGI DY S+ I S G G+ F + D F+IKT
Sbjct: 124 DFRFKTYAPVAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKT 183
Query: 152 VSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTV 211
V ++ + +L Y+ + + + TLLP+F G+Y + G +VV N+ + +
Sbjct: 184 VQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKM 242
Query: 212 HRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNE-GQKLHVGEESKKNFLEKLKRDVEF 270
H KYDLKGST R AS KE+ K LPTFKD DFL + L + + + L+RD
Sbjct: 243 HIKYDLKGSTYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLV 302
Query: 271 LAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNL 330
L KIMDYSLL+ IH++D A++E + E +
Sbjct: 303 LQSFKIMDYSLLMSIHNIDHAQREPLSSETQ----------------------------- 333
Query: 331 LSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDIL----------TPYDTKKKA 380
Y++ + +P+K +Y A+ I T KK
Sbjct: 334 ------------------YSVDTRRPAPQKALYSTAMESIQGEARRGGTMETDDQFVKKL 375
Query: 381 AHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSN 413
H+ K + H G +S P Y++RF FM N
Sbjct: 376 EHSWKALVHD-GDTVSVHRPGFYAERFQRFMCN 407
>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 1 [Homo sapiens]
Length = 394
Score = 103 bits (256), Expect = 4e-22
Identities = 84/320 (26%), Positives = 155/320 (48%), Gaps = 46/320 (14%)
Query: 103 FRNLRERFGIDDQDYQNSVTRSAP-INSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMH 161
F LR G+ ++DYQ ++ P + S + F ++D+RF +KT +V +
Sbjct: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
Query: 162 NILKKYHQFIVECHGNTLLPQFLGMYRLTVD-GVETYMVVTRNVFSHRLTVHRKYDLKGS 220
L +Y Q + + H ++LL + LG++ L VD G +TY +V ++VF + +YD+KG
Sbjct: 165 AHLPRYVQHL-QRHPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
Query: 221 TVAREASDKEKAKDLP-TFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDY 279
V+R + L KD +F +G+ +++G + + FL +++ D FL +L ++DY
Sbjct: 224 EVSRWVDPAPEGSPLVLVLKDLNF--QGKTINLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
Query: 280 SLLVG---IHDVDRAEQEEM-----EVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLL 331
SLL+ +H+ +R + + A+ E E+ LL PD+P L
Sbjct: 281 SLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPE-ESRAQNRRLL------PDAPNAL- 332
Query: 332 SFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGA 391
H ++ YF+ ++D+ T Y +K+ H KT+++
Sbjct: 333 ----------------------HILDGPEQRYFLGVVDLATVYGLRKRLEHLWKTLRY-P 369
Query: 392 GAEISTVNPEQYSKRFNEFM 411
G STV+P +Y++R +++
Sbjct: 370 GRTFSTVSPARYARRLCQWV 389
>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 2 [Homo sapiens]
Length = 191
Score = 60.5 bits (145), Expect = 3e-09
Identities = 53/219 (24%), Positives = 101/219 (46%), Gaps = 43/219 (19%)
Query: 202 RNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLP-TFKDNDFLNEGQKLHVGEESKKNF 260
++VF + +YD+KG V+R + L KD +F +G+ +++G + + F
Sbjct: 2 QSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNF--QGKTINLGPQ-RSWF 58
Query: 261 LEKLKRDVEFLAQLKIMDYSLLVG---IHDVDRAEQEEM-----EVEERAEDEECENDGV 312
L +++ D FL +L ++DYSLL+ +H+ +R + + A+ E E+
Sbjct: 59 LRQMELDTTFLRELNVLDYSLLIAFQRLHEDERGPGSSLIFRTARSVQGAQSPE-ESRAQ 117
Query: 313 GGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILT 372
LL PD+P L H ++ YF+ ++D+ T
Sbjct: 118 NRRLL------PDAPNAL-----------------------HILDGPEQRYFLGVVDLAT 148
Query: 373 PYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFM 411
Y +K+ H KT+++ G STV+P +Y++R +++
Sbjct: 149 VYGLRKRLEHLWKTLRY-PGRTFSTVSPARYARRLCQWV 186
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 57.0 bits (136), Expect = 3e-08
Identities = 56/210 (26%), Positives = 92/210 (43%), Gaps = 15/210 (7%)
Query: 91 SRFKFKEYCPMVFRNLRERF-GIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVI 149
++F + Y F +RE ++D+ S++ S+P + G+ G F T D RF++
Sbjct: 1818 AKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARG-GKSGAAFYATEDDRFIL 1876
Query: 150 KTVSSEDVAEMHNILKKYHQFI---VECHGNTLLPQFLGMYRLTVDGVETY------MVV 200
K + +V + Y +I V+ T L + LG+YR+ + ++V
Sbjct: 1877 KQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLV 1936
Query: 201 TRNVFSHRLTVHRKYDLKGSTVAREA-SDKEKAKDLPTFKDNDFLN--EGQKLHVGEESK 257
N+F R + + +DLKGS R +D K D + L L++ SK
Sbjct: 1937 MENLFYGR-KMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSK 1995
Query: 258 KNFLEKLKRDVEFLAQLKIMDYSLLVGIHD 287
+ D FL+ I+DYSLLVG D
Sbjct: 1996 AVLRTSIHSDSHFLSSHLIIDYSLLVGRDD 2025
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 33.5 bits (75), Expect = 0.37
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 212 HRKYDLKGSTVAR----EASDKE----KAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEK 263
HR +L+ + V+R E DK K D+ TF + + +NE +LH +N LE+
Sbjct: 4481 HRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQ 4540
Query: 264 LKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEE 295
L L+ ++L +++VD + E
Sbjct: 4541 SPEYENLLLTLQRTGQTILPSLNEVDHSYLSE 4572
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 33.5 bits (75), Expect = 0.37
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 212 HRKYDLKGSTVAR----EASDKE----KAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEK 263
HR +L+ + V+R E DK K D+ TF + + +NE +LH +N LE+
Sbjct: 4552 HRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQ 4611
Query: 264 LKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEE 295
L L+ ++L +++VD + E
Sbjct: 4612 SPEYENLLLTLQRTGQTILPSLNEVDHSYLSE 4643
>gi|188536080 4-aminobutyrate aminotransferase precursor [Homo
sapiens]
Length = 500
Score = 32.7 bits (73), Expect = 0.62
Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 325 DSPGNLLSFPR------FFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKK 378
D P ++++F + FF EF P+ + P K + +I+I+ D
Sbjct: 347 DDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLN 406
Query: 379 KAAHAAKTVKHG 390
AAHA K + G
Sbjct: 407 NAAHAGKALLTG 418
>gi|38679950 4-aminobutyrate aminotransferase precursor [Homo
sapiens]
Length = 500
Score = 32.7 bits (73), Expect = 0.62
Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 325 DSPGNLLSFPR------FFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKK 378
D P ++++F + FF EF P+ + P K + +I+I+ D
Sbjct: 347 DDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLN 406
Query: 379 KAAHAAKTVKHG 390
AAHA K + G
Sbjct: 407 NAAHAGKALLTG 418
>gi|38679946 4-aminobutyrate aminotransferase precursor [Homo
sapiens]
Length = 500
Score = 32.7 bits (73), Expect = 0.62
Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 6/72 (8%)
Query: 325 DSPGNLLSFPR------FFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKK 378
D P ++++F + FF EF P+ + P K + +I+I+ D
Sbjct: 347 DDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLN 406
Query: 379 KAAHAAKTVKHG 390
AAHA K + G
Sbjct: 407 NAAHAGKALLTG 418
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 32.7 bits (73), Expect = 0.62
Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query: 254 EESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVG 313
+E++KN ++ +++ V+++ QL ++ S L H ++ + V+E D C+ G+G
Sbjct: 1368 KEAQKNAIQIVQQAVKYVGQLAVLKGSKL---HFLENGNNKAASVQEEFMDAVCDGVGLG 1424
Query: 314 GNLLCSYG 321
+L G
Sbjct: 1425 MKILLDSG 1432
>gi|225735631 mesoderm induction early response 1 isoform g [Homo
sapiens]
Length = 470
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 51 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 108
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 109 EEEGEDDEDADNDDNSG 125
>gi|225735617 mesoderm induction early response 1 isoform h [Homo
sapiens]
Length = 485
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 7 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 64
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 65 EEEGEDDEDADNDDNSG 81
>gi|225735615 mesoderm induction early response 1 isoform a [Homo
sapiens]
Length = 529
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 51 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 108
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 109 EEEGEDDEDADNDDNSG 125
>gi|118130872 mesoderm induction early response 1 isoform f [Homo
sapiens]
Length = 433
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 34 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 91
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 92 EEEGEDDEDADNDDNSG 108
>gi|225735612 mesoderm induction early response 1 isoform e [Homo
sapiens]
Length = 486
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 87 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 144
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 145 EEEGEDDEDADNDDNSG 161
>gi|225735610 mesoderm induction early response 1 isoform d [Homo
sapiens]
Length = 450
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 51 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 108
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 109 EEEGEDDEDADNDDNSG 125
>gi|118130815 mesoderm induction early response 1 isoform c [Homo
sapiens]
Length = 512
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 34 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 91
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 92 EEEGEDDEDADNDDNSG 108
>gi|225735607 mesoderm induction early response 1 isoform b [Homo
sapiens]
Length = 565
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 87 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 144
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 145 EEEGEDDEDADNDDNSG 161
>gi|225735605 mesoderm induction early response 1 isoform a [Homo
sapiens]
Length = 529
Score = 32.3 bits (72), Expect = 0.81
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 240 DNDFLNEGQKLHVGEESKKNFLEKLKR--DVEFLAQLKIMDYSLLVGIHDVDRAEQEEME 297
D++ E +++ GE + + +E L R D+ L + Y V + + D E+EE E
Sbjct: 51 DDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEED--EEEEEE 108
Query: 298 VEERAEDEECENDGVGG 314
EE +DE+ +ND G
Sbjct: 109 EEEGEDDEDADNDDNSG 125
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,689,258
Number of Sequences: 37866
Number of extensions: 729970
Number of successful extensions: 3491
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 3322
Number of HSP's gapped (non-prelim): 128
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.