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Search of human proteins with 13124879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A
[Homo sapiens]
(1972 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 3793 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 3786 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 3708 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 3701 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 2979 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 2954 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 2464 0.0
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 2457 0.0
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 2440 0.0
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 1445 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 1435 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 1432 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 1424 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 1424 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1423 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1423 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 1420 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 1387 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 1387 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 1241 0.0
gi|153945715 myosin VC [Homo sapiens] 607 e-173
gi|28416946 myosin 18A isoform a [Homo sapiens] 600 e-171
gi|42794779 myosin 18A isoform b [Homo sapiens] 598 e-170
gi|215982794 myosin VA isoform 2 [Homo sapiens] 598 e-170
gi|122937345 myosin VB [Homo sapiens] 596 e-170
gi|215982791 myosin VA isoform 1 [Homo sapiens] 596 e-170
gi|154354979 myosin X [Homo sapiens] 513 e-145
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 497 e-140
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 497 e-140
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 497 e-140
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 3793 bits (9836), Expect = 0.0
Identities = 1972/1972 (100%), Positives = 1972/1972 (100%)
Query: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
Query: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
Query: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
Query: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS
Sbjct: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
Query: 241 RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL
Sbjct: 241 RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
Query: 301 LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV
Sbjct: 301 LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
Query: 361 FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA
Sbjct: 361 FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
Query: 421 VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN
Sbjct: 421 VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
Query: 481 EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW
Sbjct: 481 EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
Query: 541 FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN
Sbjct: 541 FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
Query: 601 DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ
Sbjct: 601 DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
Query: 661 LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661 LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
Query: 721 FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE
Sbjct: 721 FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
Query: 781 ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK
Sbjct: 781 ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
Query: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Query: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE
Sbjct: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
Query: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
Query: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
Query: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
Query: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Query: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
Query: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
Query: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Query: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
Query: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
Query: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
Query: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
Query: 1921 VNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE 1972
VNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE
Sbjct: 1921 VNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE 1972
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 3786 bits (9818), Expect = 0.0
Identities = 1972/1979 (99%), Positives = 1972/1979 (99%), Gaps = 7/1979 (0%)
Query: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
Query: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
Query: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
Query: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSIT-------GELEKQLLQANPILEAFGNAKT 233
GAGKTENTKKVIQYLAVVASSHKGKKDTSIT GELEKQLLQANPILEAFGNAKT
Sbjct: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT 240
Query: 234 VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 293
VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE
Sbjct: 241 VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 300
Query: 294 KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 353
KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV
Sbjct: 301 KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 360
Query: 354 LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 413
LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT
Sbjct: 361 LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 420
Query: 414 KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 473
KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ
Sbjct: 421 KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 480
Query: 474 LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 533
LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA
Sbjct: 481 LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 540
Query: 534 LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 593
LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT
Sbjct: 541 LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 600
Query: 594 KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 653
KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV
Sbjct: 601 KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 660
Query: 654 GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 713
GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ
Sbjct: 661 GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 720
Query: 714 GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 773
GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG
Sbjct: 721 GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 780
Query: 774 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 833
VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ
Sbjct: 781 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 840
Query: 834 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 893
WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ
Sbjct: 841 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900
Query: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML
Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020
Query: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080
Query: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1253
VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260
Query: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Query: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440
Query: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500
Query: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620
Query: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680
Query: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1733
TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1740
Query: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800
Query: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860
Query: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920
Query: 1914 NEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE 1972
NEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE
Sbjct: 1921 NEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETDTRDADFNGTKASE 1979
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 3708 bits (9616), Expect = 0.0
Identities = 1929/1929 (100%), Positives = 1929/1929 (100%)
Query: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
Query: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
Query: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
Query: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS
Sbjct: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
Query: 241 RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL
Sbjct: 241 RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
Query: 301 LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV
Sbjct: 301 LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
Query: 361 FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA
Sbjct: 361 FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
Query: 421 VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN
Sbjct: 421 VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
Query: 481 EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW
Sbjct: 481 EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
Query: 541 FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN
Sbjct: 541 FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
Query: 601 DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ
Sbjct: 601 DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
Query: 661 LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661 LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
Query: 721 FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE
Sbjct: 721 FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
Query: 781 ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK
Sbjct: 781 ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
Query: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET
Sbjct: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Query: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE
Sbjct: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
Query: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
Query: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
Query: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
Query: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Query: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
Query: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
Query: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
Query: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
Query: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
Query: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
Query: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
Query: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
Query: 1921 VNALKSKLR 1929
VNALKSKLR
Sbjct: 1921 VNALKSKLR 1929
Score = 253 bits (646), Expect = 1e-66
Identities = 231/976 (23%), Positives = 455/976 (46%), Gaps = 90/976 (9%)
Query: 1021 KAKNLTKLKNKHESMIS---ELEVRLKKEEKSRQELEKLKRK---LEGDASDFHEQI--- 1071
K K L ++ + E M + EL+ ++++K+ EL++L++K L + + EQ+
Sbjct: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
Query: 1072 ADLQAQIAELKMQLAKKEEELQAAL----ARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
+L A+ E++++LA K++EL+ L ARL++E + + +++ + DL+E L
Sbjct: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
Query: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1187
+ E AAR K + +K +++ L+ E+ D + R E+ ++ L L EE
Sbjct: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
Query: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL---- 1243
+ + +++ KH + EL +L++ ++++ L+K K+ LE + +D ++ L
Sbjct: 1020 EKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARA---ELNDKVHKLQNEVESVTGMLNEAE 1300
+ K ++ K+++L+A + L + + A EL + LQ +++S N+AE
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138
Query: 1301 GKAIKLAKDVASLSSQLQDT-------QEL--------------LQEETRQKLNVSTKLR 1339
+ L +++ +L ++L+DT QEL L EETR ++R
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1198
Query: 1340 QLEEER-NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Q + L +QL++ AK NL+++ TL + +D +L+ + +E KK+ +
Sbjct: 1199 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
+++ L + + A +L ++LQ E++ + L+ L K L
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ 1318
Query: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
+ + + + ++ + R+ E + SL L+E +EAK+ LER L ++ D
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
D V LE+ K+ + ++E + Q EE E K RL+ + L +
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV--VDL 1436
Query: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
D Q + N EK+++ QL L +E+ + A + + E + ++ E +A S +
Sbjct: 1437 DNQRQLVSNLEKKQRKFDQL------LAEEKNISSKYADERDRAEAEAREKETKALSLAR 1490
Query: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD-------LMQ 1691
EEA++ +L+ K + E+ED +S+D++ E EK ++LE L +
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 1692 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR-LEARIAQLEEELEEEQG 1750
L+++L A E A+ + ++ + L + L R+ +EKRR L+ ++ + E ELE+E+
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
Query: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
+ +K + L EL + S + E A +QL + +++ E+E A S
Sbjct: 1611 QRALAAAAKKKLEGDLKDL--ELQAD-SAIKGREEAIKQLRKLQAQMKDFQRELEDARAS 1667
Query: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1870
+ +++ A+E + KSL+ +L+E L E RK A+ KE
Sbjct: 1668 R----------------DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 1871 QAEK-------GNARVKQLKRQLE----EAEEESQRINANRRKLQRELDEATESNEAMGR 1919
+ + G ++ KR+LE + EEE + N + + +AT+ E +
Sbjct: 1712 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 1771
Query: 1920 EVNALKSKLRRGNETS 1935
E+ +S ++ NE++
Sbjct: 1772 ELATERSTAQK-NESA 1786
Score = 167 bits (422), Expect = 1e-40
Identities = 150/636 (23%), Positives = 281/636 (44%), Gaps = 98/636 (15%)
Query: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
K + +T+Q EE A D+L+KTK R Q+ ++L LE+K + L
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENEL-----------KELEQKHSQ----LT 886
Query: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAK-EELERTNKMLKAEME 1514
EEKN+ + AEA E + + + LEE L EA+ EE E + L+AE +
Sbjct: 887 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 946
Query: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1574
+ D+ + + E E +++ L+ + + ++++LEDE+ +D +L + L+
Sbjct: 947 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1006
Query: 1575 QFERDLQARDEQNEEKRRQLQR-------QLHEYETELEDERKQRALAAAAKKKLEGDLK 1627
+ DL + EEK + L + + E E L+ E K R K+KLEGD
Sbjct: 1007 RIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 1628 DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1687
D Q + Q+ +L+ Q+ + EL+ A A D+ A KK + LE
Sbjct: 1066 DFHEQI-------ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
Query: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELAS-------SLSGRNALQDEKRRLEARIAQ 1740
+ LQEDL + AR +A+ +K +L EEL + +L Q+ + + E +
Sbjct: 1119 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1178
Query: 1741 LEEELEEEQGNMEAMSDRVRKA--------TQQAEQ---------------------LSN 1771
L++ L+EE + EA +R+ T+Q EQ L+
Sbjct: 1179 LKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG 1238
Query: 1772 ELATERSTAQKNESARQQLERQNKELRSK--------------LHEMEGAVKS------- 1810
EL Q+ E +++LE Q +EL+SK +H+++ V+S
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
Query: 1811 ------KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
K +A+L +++ +E +++E R+K + L+Q +++ + Q+++E +
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
Query: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
+ + N ++ K++L++ + + +++ Q+E++ T+ E + L
Sbjct: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
Query: 1925 -KSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1959
K+K R E + R+++ N + + + D
Sbjct: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 3701 bits (9598), Expect = 0.0
Identities = 1929/1936 (99%), Positives = 1929/1936 (99%), Gaps = 7/1936 (0%)
Query: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
Query: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
Query: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
Query: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSIT-------GELEKQLLQANPILEAFGNAKT 233
GAGKTENTKKVIQYLAVVASSHKGKKDTSIT GELEKQLLQANPILEAFGNAKT
Sbjct: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT 240
Query: 234 VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 293
VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE
Sbjct: 241 VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 300
Query: 294 KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 353
KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV
Sbjct: 301 KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 360
Query: 354 LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 413
LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT
Sbjct: 361 LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 420
Query: 414 KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 473
KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ
Sbjct: 421 KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 480
Query: 474 LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 533
LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA
Sbjct: 481 LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 540
Query: 534 LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 593
LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT
Sbjct: 541 LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 600
Query: 594 KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 653
KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV
Sbjct: 601 KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 660
Query: 654 GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 713
GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ
Sbjct: 661 GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 720
Query: 714 GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 773
GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG
Sbjct: 721 GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 780
Query: 774 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 833
VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ
Sbjct: 781 VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 840
Query: 834 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 893
WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ
Sbjct: 841 WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900
Query: 894 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML
Sbjct: 901 EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020
Query: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080
Query: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200
Query: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1253
VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260
Query: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320
Query: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380
Query: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440
Query: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500
Query: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560
Query: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620
Query: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680
Query: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1733
TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1740
Query: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800
Query: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860
Query: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920
Query: 1914 NEAMGREVNALKSKLR 1929
NEAMGREVNALKSKLR
Sbjct: 1921 NEAMGREVNALKSKLR 1936
Score = 253 bits (646), Expect = 1e-66
Identities = 231/976 (23%), Positives = 455/976 (46%), Gaps = 90/976 (9%)
Query: 1021 KAKNLTKLKNKHESMIS---ELEVRLKKEEKSRQELEKLKRK---LEGDASDFHEQI--- 1071
K K L ++ + E M + EL+ ++++K+ EL++L++K L + + EQ+
Sbjct: 847 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 906
Query: 1072 ADLQAQIAELKMQLAKKEEELQAAL----ARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
+L A+ E++++LA K++EL+ L ARL++E + + +++ + DL+E L
Sbjct: 907 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 966
Query: 1128 DSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET 1187
+ E AAR K + +K +++ L+ E+ D + R E+ ++ L L EE
Sbjct: 967 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026
Query: 1188 RSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL---- 1243
+ + +++ KH + EL +L++ ++++ L+K K+ LE + +D ++ L
Sbjct: 1027 EKAK-NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARA---ELNDKVHKLQNEVESVTGMLNEAE 1300
+ K ++ K+++L+A + L + + A EL + LQ +++S N+AE
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145
Query: 1301 GKAIKLAKDVASLSSQLQDT-------QEL--------------LQEETRQKLNVSTKLR 1339
+ L +++ +L ++L+DT QEL L EETR ++R
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMR 1205
Query: 1340 QLEEER-NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Q + L +QL++ AK NL+++ TL + +D +L+ + +E KK+ +
Sbjct: 1206 QKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
+++ L + + A +L ++LQ E++ + L+ L K L
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ 1325
Query: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
+ + + + ++ + R+ E + SL L+E +EAK+ LER L ++ D
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
D V LE+ K+ + ++E + Q EE E K RL+ + L +
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV--VDL 1443
Query: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
D Q + N EK+++ QL L +E+ + A + + E + ++ E +A S +
Sbjct: 1444 DNQRQLVSNLEKKQRKFDQL------LAEEKNISSKYADERDRAEAEAREKETKALSLAR 1497
Query: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD-------LMQ 1691
EEA++ +L+ K + E+ED +S+D++ E EK ++LE L +
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 1692 LQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR-LEARIAQLEEELEEEQG 1750
L+++L A E A+ + ++ + L + L R+ +EKRR L+ ++ + E ELE+E+
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1617
Query: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
+ +K + L EL + S + E A +QL + +++ E+E A S
Sbjct: 1618 QRALAAAAKKKLEGDLKDL--ELQAD-SAIKGREEAIKQLRKLQAQMKDFQRELEDARAS 1674
Query: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKE 1870
+ +++ A+E + KSL+ +L+E L E RK A+ KE
Sbjct: 1675 R----------------DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 1871 QAEK-------GNARVKQLKRQLE----EAEEESQRINANRRKLQRELDEATESNEAMGR 1919
+ + G ++ KR+LE + EEE + N + + +AT+ E +
Sbjct: 1719 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 1778
Query: 1920 EVNALKSKLRRGNETS 1935
E+ +S ++ NE++
Sbjct: 1779 ELATERSTAQK-NESA 1793
Score = 167 bits (422), Expect = 1e-40
Identities = 150/636 (23%), Positives = 281/636 (44%), Gaps = 98/636 (15%)
Query: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
K + +T+Q EE A D+L+KTK R Q+ ++L LE+K + L
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENEL-----------KELEQKHSQ----LT 893
Query: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAK-EELERTNKMLKAEME 1514
EEKN+ + AEA E + + + LEE L EA+ EE E + L+AE +
Sbjct: 894 EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 953
Query: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1574
+ D+ + + E E +++ L+ + + ++++LEDE+ +D +L + L+
Sbjct: 954 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1013
Query: 1575 QFERDLQARDEQNEEKRRQLQR-------QLHEYETELEDERKQRALAAAAKKKLEGDLK 1627
+ DL + EEK + L + + E E L+ E K R K+KLEGD
Sbjct: 1014 RIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 1628 DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1687
D Q + Q+ +L+ Q+ + EL+ A A D+ A KK + LE
Sbjct: 1073 DFHEQI-------ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1125
Query: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELAS-------SLSGRNALQDEKRRLEARIAQ 1740
+ LQEDL + AR +A+ +K +L EEL + +L Q+ + + E +
Sbjct: 1126 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1185
Query: 1741 LEEELEEEQGNMEAMSDRVRKA--------TQQAEQ---------------------LSN 1771
L++ L+EE + EA +R+ T+Q EQ L+
Sbjct: 1186 LKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG 1245
Query: 1772 ELATERSTAQKNESARQQLERQNKELRSK--------------LHEMEGAVKS------- 1810
EL Q+ E +++LE Q +EL+SK +H+++ V+S
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305
Query: 1811 ------KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864
K +A+L +++ +E +++E R+K + L+Q +++ + Q+++E +
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1365
Query: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
+ + N ++ K++L++ + + +++ Q+E++ T+ E + L
Sbjct: 1366 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1425
Query: 1925 -KSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1959
K+K R E + R+++ N + + + D
Sbjct: 1426 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 2979 bits (7724), Expect = 0.0
Identities = 1504/1972 (76%), Positives = 1751/1972 (88%), Gaps = 4/1972 (0%)
Query: 1 MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
MAQ+ L D E++LFVD+ I +P QADW AK+LVW+PSE+ GFEAASIKEE+GDEV+V
Sbjct: 1 MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60
Query: 61 ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
EL ENGKK V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL++RY+SGLIYTYSGL
Sbjct: 61 ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120
Query: 121 FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
FCVV+NPYK+LPIYSE I++MY+GKKRHEMPPHIYAI+++AYR MLQDREDQSILCTGES
Sbjct: 121 FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180
Query: 181 GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
GAGKTENTKKVIQYLA VASSHKG+KD +I GELE+QLLQANPILE+FGNAKTVKNDNSS
Sbjct: 181 GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS 240
Query: 241 RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
RFGKFIRINFDVTGYIVGANIETYLLEKSRA+RQA+DERTFHIFY +++GA E ++SDLL
Sbjct: 241 RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL 300
Query: 301 LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
LEGFNNY FLSNG++PIP QD + FQET+EAM IMGFS EE LS+LKVVSSVLQ GNI
Sbjct: 301 LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS 360
Query: 361 FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
FKKERNTDQASMP+NT AQK+CHL+G+NV +FTR+ILTPRIKVGRD VQKAQTKEQADFA
Sbjct: 361 FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA 420
Query: 421 VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
VEALAKATYERLFRW++ R+NKALD+T RQGASF+GILDIAGFEIFE+NSFEQLCINYTN
Sbjct: 421 VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN 480
Query: 481 EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIERP NPPGVLALLDEECW
Sbjct: 481 EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW 540
Query: 541 FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
FPKATDK+FVEKL EQGSH KFQKP+QLKDK +F IIHYAGKVDY A WL KNMDPLN
Sbjct: 541 FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN 600
Query: 601 DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
DNV +LL+ SSD+FVA+LWKDVDRIVGLDQ+ MTE++ SA KTKKGMFRTVGQLYKE
Sbjct: 601 DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES 660
Query: 661 LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
L KLM TLRNT PNFVRCIIPNHEKR+GKLD LVL+QLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661 LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV 720
Query: 721 FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
FQEFRQRYEIL NAIPKGFMDGKQAC MI+ALELDPNLYRIGQSKIFFR GVLAHLEE
Sbjct: 721 FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE 780
Query: 781 ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
ERDLKITD+I+ FQA+CRGYLARKAFAK+QQQL+A+KV+QRNCAAYLKLR+WQWWR+FTK
Sbjct: 781 ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK 840
Query: 841 VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
VKPLLQVTRQEEE+QAK++EL K KE+Q K E EL+E+E+KH QL EEKN+L EQLQAET
Sbjct: 841 VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET 900
Query: 901 ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
EL+AEAEEMR RLAAKKQELEEILH++E+R+EEEE+R Q LQ E+KKM + DLEEQL+
Sbjct: 901 ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
Query: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
EEE ARQKLQLEKVTAEAKIKK+E+EIL+++DQN+K KE+KL+E+RI++ ++ LAEEEE
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020
Query: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
KAKNL K++NK E MIS+LE RLKKEEK+RQELEK KRKL+G+ +D +QIA+LQAQI E
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080
Query: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
LK+QLAKKEEELQ ALAR DDE KNNALK +REL+ I++LQED +SE+A+RNKAEKQ
Sbjct: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140
Query: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
KRDL EELEALKTELEDTLD+TA QQELR KREQEV LKKAL+EET++HEAQ+Q+MRQ+
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
Query: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
HA A+EEL+EQLEQ KR KANL+KNKQ LE +N +LA E++VL Q K E EHK+KKL+AQ
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
Query: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
VQEL +K S+G+R R EL +K KLQNE+++V+ +L EAE K IK AKD ASL SQLQDT
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
QELLQEETRQKLN+S+++RQLEEE+NSLQ+Q +EE EA++NLE+ + L QL+D+KKK+
Sbjct: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380
Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
D T+E+LEE KK+ K+ E L+Q+ EEKA AYDKLEKTKNRLQQELDDL VDLD+QR
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
Query: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
Q+ SNLEKKQ+KFDQLLAEEK+IS++YA+ERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500
Query: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
E ER NK L+A+MEDL+SSKDDVGKNVHELEKSKRALE Q+EEM+TQLEELEDELQATED
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560
Query: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
AKLRLEVNMQA+K QFERDLQ RDEQNEEK+R L +Q+ E E ELEDERKQRALA A+KK
Sbjct: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620
Query: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
K+E DLKDLE Q ++A K R+E IKQLRKLQAQMKD+QRELE+ARASRDEIFA +KE+EK
Sbjct: 1621 KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK 1680
Query: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
K KSLEA+++QLQE+LA++ERAR+ A+ E++ELA+E+ +S SG++AL DEKRRLEARIAQ
Sbjct: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740
Query: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
LEEELEEEQ NME ++DR RK T Q + L+ ELA ERS AQK+++ARQQLERQNKEL++K
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800
Query: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
L E+EGAVKSKFK+TI+ALEAKI QLEEQ+EQEA+E+ AA K +++ +KKLKEI +QVED
Sbjct: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860
Query: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
ER+ A+QYKEQ EK NAR+KQLKRQLEEAEEE+ R NA+RRKLQRELD+ATE+NE + RE
Sbjct: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920
Query: 1921 VNALKSKLRRGNETSFVPSRRSGGRRV-IENA--DGSEEETDTRDADFNGTK 1969
V+ LK++LRRG SF S RSG R++ +E A + S+++T+++ +D N T+
Sbjct: 1921 VSTLKNRLRRGGPISF-SSSRSGRRQLHLEGASLELSDDDTESKTSDVNETQ 1971
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 2954 bits (7657), Expect = 0.0
Identities = 1496/1965 (76%), Positives = 1737/1965 (88%), Gaps = 14/1965 (0%)
Query: 11 EKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVT 70
+K+L+VDKNFIN+P+AQADWAAK+LVWVPS+K GFE AS+KEE G+E +VELVENGKKV
Sbjct: 7 DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66
Query: 71 VGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKH 130
V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL+ERY+SGLIYTYSGLFCVV+NPYK+
Sbjct: 67 VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126
Query: 131 LPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKK 190
LPIYSE+IV+MYKGKKRHEMPPHIYAI DTAYRSM+QDREDQSILCTGESGAGKTENTKK
Sbjct: 127 LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186
Query: 191 VIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 250
VIQYLA VASSHK KKD GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF
Sbjct: 187 VIQYLAYVASSHKSKKDQ---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 243
Query: 251 DVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFL 310
DV GYIVGANIETYLLEKSRAIRQA++ERTFHIFYY+++GA E +++DLLLE +N Y FL
Sbjct: 244 DVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL 303
Query: 311 SNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQA 370
SNG V IP QD +MFQET+EAM IMG EEEQ+ +L+V+S VLQLGNIVFKKERNTDQA
Sbjct: 304 SNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQA 363
Query: 371 SMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYE 430
SMPDNTAAQKV HL+GINVTDFTR ILTPRIKVGRD VQKAQTKEQADFA+EALAKATYE
Sbjct: 364 SMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYE 423
Query: 431 RLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHT 490
R+FRW++ R+NKALDKT RQGASF+GILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHT
Sbjct: 424 RMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHT 483
Query: 491 MFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFV 550
MFILEQEEYQREGIEWNFIDFGLDLQPCI+LIE+P PPG+LALLDEECWFPKATDKSFV
Sbjct: 484 MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFV 543
Query: 551 EKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNAS 610
EK+ EQG+HPKFQKPKQLKDK +F IIHYAGKVDY A WL KNMDPLNDN+ +LL+ S
Sbjct: 544 EKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQS 603
Query: 611 SDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRN 670
SDKFV++LWKDVDRI+GLDQ+A M+E++LP A KT+KGMFRTVGQLYKEQL KLM TLRN
Sbjct: 604 SDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRN 663
Query: 671 TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730
T PNFVRCIIPNHEK++GKLD LVL+QLRCNGVLEGIRICRQGFPNR+VFQEFRQRYEI
Sbjct: 664 TNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEI 723
Query: 731 LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVI 790
L N+IPKGFMDGKQAC+LMIKALELD NLYRIGQSK+FFR GVLAHLEEERDLKITDVI
Sbjct: 724 LTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVI 783
Query: 791 MAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQ 850
+ FQA CRGYLARKAFAKRQQQLTAMKV+QRNCAAYLKLRNWQWWRLFTKVKPLLQV+RQ
Sbjct: 784 IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843
Query: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
EEEM AKE+EL K +E+Q AEN L E+E SQL EK LQEQLQAETEL AEAEE+R
Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903
Query: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
RL AKKQELEEI H++EAR+EEEE+R Q LQAE+KKM Q + +LEEQLEEEE+ARQKLQ
Sbjct: 904 ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963
Query: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
LEKVT EAK+KKLE+E ++++DQN KL+KE+KLLE+RI++ TTNL EEEEK+K+L KLKN
Sbjct: 964 LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKN 1023
Query: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
KHE+MI++LE RL++EEK RQELEK +RKLEGD++D +QIA+LQAQIAELKMQLAKKEE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
ELQAALAR+++E AQKN ALKKIRELE IS+LQEDL+SERA+RNKAEKQKRDLGEELEA
Sbjct: 1084 ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA 1143
Query: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
LKTELEDTLDSTA QQELR+KREQEV +LKK L+EE ++HEAQ+QEMRQKH+QAVEEL E
Sbjct: 1144 LKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203
Query: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
QLEQ KR KANL+K KQTLE E +LA E++VL Q K + EHK+KK+EAQ+QELQ K ++
Sbjct: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263
Query: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
GER R EL DKV KLQ E+++VTG+L++++ K+ KL KD ++L SQLQDTQELLQEE RQ
Sbjct: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ 1323
Query: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1390
KL++STKL+Q+E+E+NS ++QL+EE EAK NLE+ I+TL+ Q++D KKK++D +E
Sbjct: 1324 KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETA 1383
Query: 1391 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
EE K++ QK++E L+Q++EEK AAYDKLEKTK RLQQELDDL+VDLD+QRQ NLEKKQ
Sbjct: 1384 EEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ 1443
Query: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510
+KFDQLLAEEK IS+KYA+ERDRAEAEAREKETKALSLARALEEA+E K ELER NK +
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503
Query: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
EMEDL+SSKDDVGK+VHELEKSKRALE Q+EEMKTQLEELEDELQATEDAKLRLEVN+Q
Sbjct: 1504 TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ 1563
Query: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
A+K QFERDLQ RDEQ+EEK++QL RQ+ E E ELEDERKQR++A AA+KKLE DLKDLE
Sbjct: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690
DSA K R+EAIKQLRKLQAQMKD REL+D RASR+EI A AKENEKK KS+EA+++
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
Query: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ-DEKRRLEARIAQLEEELEEEQ 1749
QLQE+LAAAERA++QA E++ELA+E+A+S SG+ AL +EKRRLEARIAQLEEELEEEQ
Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLEEELEEEQ 1742
Query: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1809
GN E ++DR++KA Q +Q++ +L ERS AQKNE+ARQQLERQNKEL+ KL EMEG VK
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802
Query: 1810 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYK 1869
SK+K++I ALEAKIAQLEEQ++ E +E+QAA K +++ +KKLK++LLQV+DER+ AEQYK
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862
Query: 1870 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
+QA+K + R+KQLKRQLEEAEEE+QR NA+RRKLQREL++ATE+ +AM REV++LK+KLR
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922
Query: 1930 RGNETSFVPSR--RSGGRRVIENADGSEEETDTRDADFNGTKASE 1972
RG+ VP R R G DGS+EE D + AD K +E
Sbjct: 1923 RGDLPFVVPRRMARKGA------GDGSDEEVDGK-ADGAEAKPAE 1960
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 2464 bits (6387), Expect = 0.0
Identities = 1234/1933 (63%), Positives = 1573/1933 (81%), Gaps = 5/1933 (0%)
Query: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Query: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
Query: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
Query: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
+ + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL
Sbjct: 227 EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286
Query: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMF 326
EKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P Q+ E+F
Sbjct: 287 EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERELF 345
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
QET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAAQK+C L+G
Sbjct: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405
Query: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ R+N+ALD+
Sbjct: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
+ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W
Sbjct: 466 SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKP 566
F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG HPKFQ+P
Sbjct: 526 TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585
Query: 567 KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626
+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++WKDV+ IV
Sbjct: 586 RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645
Query: 627 GLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKR 686
GL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR
Sbjct: 646 GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703
Query: 687 SGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQA 746
+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQA
Sbjct: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763
Query: 747 CILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAF 806
C MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF
Sbjct: 764 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823
Query: 807 AKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKE 866
KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E
Sbjct: 824 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883
Query: 867 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E
Sbjct: 884 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943
Query: 927 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986
+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E++
Sbjct: 944 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003
Query: 987 ILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046
+L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KE
Sbjct: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063
Query: 1047 EKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106
EK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE +
Sbjct: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123
Query: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1166
LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQ
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183
Query: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1226
ELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K +
Sbjct: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243
Query: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303
Query: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++R +E E
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363
Query: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R +E E LTQ
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423
Query: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK +
Sbjct: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483
Query: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
+ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+
Sbjct: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543
Query: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE
Sbjct: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603
Query: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQ
Sbjct: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663
Query: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
LRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA
Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723
Query: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
+++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q
Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783
Query: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ
Sbjct: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843
Query: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQL
Sbjct: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903
Query: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRR 1946
EEAEEE+ R A RR+LQREL++ TES E+M REV L+++LRRG T + R R
Sbjct: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR- 1962
Query: 1947 VIENADGSEEETD 1959
+E S+EE +
Sbjct: 1963 -LEEGVASDEEAE 1974
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 2457 bits (6368), Expect = 0.0
Identities = 1234/1941 (63%), Positives = 1573/1941 (81%), Gaps = 13/1941 (0%)
Query: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Query: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
Query: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
Query: 207 DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
+ + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
Query: 259 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
Query: 319 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Query: 379 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
Query: 439 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
Query: 499 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
Query: 559 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
Query: 619 WKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRC 678
WKDV+ IVGL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRC
Sbjct: 646 WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
Query: 679 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 738
I+PNHEKR+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPK
Sbjct: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
Query: 739 GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 798
GFMDGKQAC MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA R
Sbjct: 764 GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
Query: 799 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+
Sbjct: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
Query: 859 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918
ELQK +E QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQ
Sbjct: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
Query: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978
ELE ++ E+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EA
Sbjct: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
Query: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
K+KK E+++L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I++
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
Query: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
+E RL+KEEK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR
Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
Query: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT 1158
+DE + LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
Query: 1159 LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1218
LDST QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R
Sbjct: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
Query: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
K +K + LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE
Sbjct: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
Query: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
+K+ + Q E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++
Sbjct: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
Query: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
R +E E L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R
Sbjct: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423
Query: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
+E E LTQ+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLA
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
Query: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
EEK + +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+S
Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
Query: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
SKDDVGK+VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ER
Sbjct: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
Query: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
DLQ RDE EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
Query: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
G+EEA+KQLRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA
Sbjct: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
Query: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
++RAR+QA +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR
Sbjct: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
Query: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
RK Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAA
Sbjct: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
Query: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
LE+K+AQ EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN R
Sbjct: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
Query: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1938
VKQLKRQLEEAEEE+ R A RR+LQREL++ TES E+M REV L+++LRRG T
Sbjct: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTR 1963
Query: 1939 SRRSGGRRVIENADGSEEETD 1959
+ R R +E S+EE +
Sbjct: 1964 TVRQVFR--LEEGVASDEEAE 1982
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 2440 bits (6324), Expect = 0.0
Identities = 1234/1974 (62%), Positives = 1573/1974 (79%), Gaps = 46/1974 (2%)
Query: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Query: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
Query: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
Query: 207 DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
+ + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
Query: 259 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
Query: 319 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Query: 379 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
Query: 439 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
Query: 499 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
Query: 559 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
Query: 619 WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 645
WKD V+ IVGL+Q++ + + P +
Sbjct: 646 WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703
Query: 646 KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 705
++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+ LVL+QLRCNGVL
Sbjct: 704 RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763
Query: 706 EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 765
EGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQAC MI+ALELDPNLYR+GQ
Sbjct: 764 EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823
Query: 766 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
SKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 824 SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883
Query: 826 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885
YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E QQ++ E+ EL+ + +QL
Sbjct: 884 YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943
Query: 886 TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 945
EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+ +Q+Q E+
Sbjct: 944 EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003
Query: 946 KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063
Query: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123
Query: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE + LK +RE + +++ QE
Sbjct: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183
Query: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQELR+KREQEVT LKK L+E
Sbjct: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243
Query: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K + LE E ++L EL L
Sbjct: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303
Query: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363
Query: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
L+K+++S +QL D QELLQEETR KL + +++R +E E L++QL+EE A++ R
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
Query: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
+ T QLS+ +++ ++ A +EA EE ++R +E E LTQ+ EK D+LE+ + RL
Sbjct: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
Query: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
QQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK + +ER+RAEAE RE+E +A
Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543
Query: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
LSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R E +++
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
Query: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE EE+RRQL +QL + E E
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663
Query: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQLRK+QAQMK+ RE+E+ R
Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723
Query: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA +++E+A+E+A+ +
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783
Query: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q E L+ EL+ ERS + K ES
Sbjct: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843
Query: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ EEQ+EQE RE+ + K ++
Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903
Query: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
+ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R A RR+LQR
Sbjct: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963
Query: 1906 ELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1959
EL++ TES E+M REV L+++LRRG T + R R +E S+EE +
Sbjct: 1964 ELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR--LEEGVASDEEAE 2015
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 1445 bits (3740), Expect = 0.0
Identities = 797/1908 (41%), Positives = 1183/1908 (62%), Gaps = 27/1908 (1%)
Query: 33 KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
K+ V+VP +KQ F A I +G +V E E GK VTV +D + + NPPKF K+EDMA
Sbjct: 34 KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92
Query: 93 LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
LT L+E +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PP
Sbjct: 93 LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152
Query: 153 HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSI- 210
HI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY AV+A+ + KKD S
Sbjct: 153 HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212
Query: 211 TGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSR 270
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR
Sbjct: 213 KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272
Query: 271 AIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN---YTFLSNGFVPIPAAQDDEMFQ 327
I Q + ER +HIFY +++ K ++ LL+ NN Y F+S G + + D E
Sbjct: 273 VIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASIDDAEELM 330
Query: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
T A ++GF+ EE+ S+ K+ +++ GN+ FK ++ +QA A K +LMG+
Sbjct: 331 ATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGL 390
Query: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 447
N D + + PR+KVG + V K Q +Q +A ALAKA YER+F W++TR+N L+ T
Sbjct: 391 NSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-T 449
Query: 448 HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507
+ F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 450 KQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 509
Query: 508 FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKP 566
FIDFG+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQKP
Sbjct: 510 FIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566
Query: 567 KQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
+ +K K E FS+IHYAG VDYN WL KN DPLN+ V L SS K ++ L+ +
Sbjct: 567 RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY-- 624
Query: 625 IVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
G D + + K KKG F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 625 -AGADAPIEKGKG------KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNE 677
Query: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
K G +D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D
Sbjct: 678 TKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFID 737
Query: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
++ ++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG LA
Sbjct: 738 SRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLA 797
Query: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
R + K ++ ++ VIQ N A++ ++NW W +L+ K+KPLL+ +E+EM + ++E
Sbjct: 798 RMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFT 857
Query: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
+ KE +K+E KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 858 RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917
Query: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
+ EM RLE+EE+ +L A+++K+ + +L+ +++ E K++ EK E K+K
Sbjct: 918 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977
Query: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 978 LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGS 1037
Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ EL A AR++DE
Sbjct: 1038 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDE 1097
Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
A + KK++EL+ I +L+E+L++ER AR K EK + DL ELE + LE+ +T
Sbjct: 1098 QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1157
Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1158 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217
Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
+K K + E D+ + + +AK +E + LE Q+ E +SK + +R+ +L +
Sbjct: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277
Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
KLQ E ++ L+E E +L + + + QL+D + L+EE + K ++ L+
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337
Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397
Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
+ + E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1457
Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
+ E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL
Sbjct: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517
Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
GK +HELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L
Sbjct: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
+DE+ E+ +R R + +T L+ E + R A KKK+EGDL ++E+Q A +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
EA KQ++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER
Sbjct: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
+RK A+ E E +E + S +L ++K++++A ++QL+ E+EE ++ +K
Sbjct: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757
Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA
Sbjct: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1817
Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
++ +LE ++E E + + K +++ ++++KE+ Q E++RK + ++ +K +VK
Sbjct: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877
Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
KRQ EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1878 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
Score = 234 bits (598), Expect = 5e-61
Identities = 207/935 (22%), Positives = 428/935 (45%), Gaps = 71/935 (7%)
Query: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
K+K +S E E+ KEE +R L++ K E + E++ L + +L++Q+
Sbjct: 835 KIKPLLKSAEREKEMASMKEEFTR--LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQ 892
Query: 1087 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
+++ L A R D I K K++E+ + D +E++++E A+ KR L +
Sbjct: 893 AEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLED-EEEMNAELTAK------KRKLED 945
Query: 1147 ELEALKTELED---TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1203
E LK +++D TL ++ + + +T LDE + + +++ H Q
Sbjct: 946 ECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 1204 AVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
A+++L Q + K N L K K LE++ DL G L + + ++E K+KLE ++
Sbjct: 1006 ALDDL-----QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Query: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Q D E + +L++++ K E+ ++ + + + +L K + L +++++ +E
Sbjct: 1061 LTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEE 1120
Query: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
L+ E + V E+ R+ L +L+E E LE ++Q+ +KK+ +
Sbjct: 1121 ELEAERTARAKV-------EKLRSDLSRELEEISE---RLEEAGGATSVQIEMNKKREAE 1170
Query: 1383 FASTVEALEEG-----------KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD 1431
F LEE +K+ + L +Q + KLEK K+ + ELDD
Sbjct: 1171 FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1230
Query: 1432 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARA 1491
+ +++ + +NLEK R + + E ++ + + + ++ + +T+ L+R
Sbjct: 1231 VTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQ 1290
Query: 1492 LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEEL 1551
L+E +L R ++EDL + + E K+K AL ++ + + L
Sbjct: 1291 LDEKEALISQLTRGKLTYTQQLEDLK-------RQLEEEVKAKNALAHALQSARHDCDLL 1343
Query: 1552 EDELQATEDAKLRLEVNMQALKGQ-------FERDLQARDEQNEEKRRQLQRQLHEYETE 1604
++ + +AK L+ + + +E D R E+ EE +++L ++L E E
Sbjct: 1344 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEA 1403
Query: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
+E + + K +L+ +++DL + E + L + ++F + L +
Sbjct: 1404 VEAVNAKCSSLEKTKHRLQNEIEDLMVDV-------ERSNAAAAALDKKQRNFDKILAEW 1456
Query: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQ-------EDLAAAERARKQADLEKEELAEEL 1717
+ +E + + ++K+A+SL +L +L+ E L +R K E +L E+L
Sbjct: 1457 KQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 1516
Query: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
SS + L+ +++LEA +L+ LEE + ++E ++ +A + Q+ E+ ER
Sbjct: 1517 GSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ER 1574
Query: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA--LEAKIAQLEEQVEQEAR 1835
A+K+E Q + + S ++ +S+ ++ +E + ++E Q+ R
Sbjct: 1575 KLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANR 1634
Query: 1836 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
A K +K LK+ +Q++D + + KE R L+ +LEE ++
Sbjct: 1635 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 1896 INANRRKLQRELDEATESNEAMGREVNALKSKLRR 1930
+R+ ++EL E +E + + + +L ++ ++
Sbjct: 1695 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKK 1729
Score = 208 bits (530), Expect = 4e-53
Identities = 201/966 (20%), Positives = 430/966 (44%), Gaps = 132/966 (13%)
Query: 839 TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
TK K LQ Q+ +++QA+ED++ + + K E ++ +LE L +EK + +
Sbjct: 993 TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE---GSLEQEKKVRMDLE 1049
Query: 897 QAETELYAE---AEEMRVRLAAKKQELEEILHE-------MEARLEEEEDRGQQLQAERK 946
+A+ +L + +E + L KQ+L+E L + + AR+E+E+ G QLQ + K
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109
Query: 947 KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSK 999
++ ++ +LEE+LE E AR K++ + +++++ + + V + N K
Sbjct: 1110 ELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1169
Query: 1000 ERKLLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL- 1043
E + + + + T ++AE E+ NL ++K K E SE ++ L
Sbjct: 1170 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229
Query: 1044 ------KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
++ K++ LEK+ R LE ++ + + Q + +L Q AK + E
Sbjct: 1230 DVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSR 1289
Query: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
+LD++ A + + + DL+ L+ E A+N + + + L+ + E+
Sbjct: 1290 QLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
++ A Q + +K EV + + + +++E ++K AQ ++E E +E
Sbjct: 1350 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNA 1409
Query: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA-------QVQELQSKCSD 1270
++L+K K L+ E DL ++ A ++ K++ + + +E QS+
Sbjct: 1410 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1469
Query: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
++ L+ ++ KL+N E L + + L ++++ L+ QL + + + E +
Sbjct: 1470 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV 1529
Query: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEA 1389
+ +QLE E+ LQ L+E + ++ E I ++ + K +++ A E
Sbjct: 1530 R-------KQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1582
Query: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
+E+ K+ + +++L + + + ++ + K +++ +L+++ + L + ++ + +K+
Sbjct: 1583 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1642
Query: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1505
+ LL + + D+ RA + +E E + L LEE E+ ER+
Sbjct: 1643 VKSLQSLLKD----TQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698
Query: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE--------------- 1550
K+ + E+ + + L K+ ++ + +++T++EE
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Query: 1551 ------LEDELQATEDAKLRLE---VNMQ----------------ALKG----------- 1574
+ +EL+ +D LE NM+ ALKG
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818
Query: 1575 --QFERDLQARDEQNEEK---RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
+ E +L+A ++N E R+ +R++ E + E++RK +L+ + L
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL-------RLQDLVDKL 1871
Query: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689
+L+ + + EEA +Q ++ + Q EL++A D A ++ N+ +AKS +
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERAD--IAESQVNKLRAKSRDIGT 1929
Query: 1690 MQLQED 1695
L E+
Sbjct: 1930 KGLNEE 1935
Score = 141 bits (356), Expect = 6e-33
Identities = 145/595 (24%), Positives = 275/595 (46%), Gaps = 54/595 (9%)
Query: 1356 MEAKQNLERHISTLNIQ------LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1409
ME K+ LER S L IQ + ++ L + +R +KE+ ++ +++
Sbjct: 799 MEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAER-EKEMASMKEEFT 857
Query: 1410 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1469
A +K E + L++++ VS L++K Q+ AE+ N+ AD
Sbjct: 858 RLKEALEKSEARRKELEEKM-------------VSLLQEKNDLQLQVQAEQDNL----AD 900
Query: 1470 ERDRAEAEAREK---ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
+R + + K E K + LE+ E EL + L+ E +L DD+
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELT 960
Query: 1527 VHELEKSKRALETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDE 1585
+ ++EK K A E +++ + ++ L++ + + T++ K E + QAL DLQA ++
Sbjct: 961 LAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALD-----DLQAEED 1015
Query: 1586 QNE---EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642
+ + + +L++Q+ + E LE E+K R AK+KLEGDLK + +++
Sbjct: 1016 KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQ 1075
Query: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
++L+K ++ +ED +A ++ KE + + + LE +L + A E+
Sbjct: 1076 LDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKL 1135
Query: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
R E EE++E L + + + ++ EA ++ +LEE EA + +RK
Sbjct: 1136 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRK- 1194
Query: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
+ A+ ++ EL + Q+ +Q+LE++ E + +L ++ ++ K+ A LE
Sbjct: 1195 -KHADSVA-ELGEQIDNLQR---VKQKLEKEKSEFKLELDDVTSNMEQIIKAK-ANLEKM 1248
Query: 1823 IAQLEEQVEQ---EAREKQAATKSLKQKDKKLK----EILLQVEDERKMAEQYKEQAEKG 1875
LE+Q+ + +A E Q + L + KL+ E+ Q++++ + Q
Sbjct: 1249 CRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTY 1308
Query: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1930
+++ LKRQL EEE + NA LQ + E E A K++L+R
Sbjct: 1309 TQQLEDLKRQL---EEEVKAKNALAHALQSARHDCDLLREQYEEETEA-KAELQR 1359
Score = 103 bits (257), Expect = 2e-21
Identities = 86/376 (22%), Positives = 172/376 (45%), Gaps = 45/376 (11%)
Query: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
E M ++K +F R L+ E++E +R++L+ ++ L E+ L A+ + +
Sbjct: 846 EKEMASMKEEFTR-LKEALEKSEARRKELEEKM----VSLLQEKNDLQLQVQAE---QDN 897
Query: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
L D E + D IK + + L+A++K+ LED E+ A ++ E + L
Sbjct: 898 LADAEERCDQLIKNKIQ-------LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 950
Query: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1745
+ D+ L+ LA E+ + + + + L EE+A L EK+ L+ Q ++L
Sbjct: 951 KRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1010
Query: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME 1805
+ E+ + ++ K QQ + L L E+ E A+++LE K + + ++E
Sbjct: 1011 QAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 1806 GAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMA 1865
++Q+++ LK+KD +L + ++EDE+ +
Sbjct: 1071 ND-------------------KQQLDER----------LKKKDFELNALNARIEDEQALG 1101
Query: 1866 EQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALK 1925
Q +++ ++ AR+++L+ +LE ++ R L REL+E +E E G +++
Sbjct: 1102 SQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG-GATSVQ 1160
Query: 1926 SKLRRGNETSFVPSRR 1941
++ + E F RR
Sbjct: 1161 IEMNKKREAEFQKMRR 1176
Score = 39.7 bits (91), Expect = 0.029
Identities = 32/148 (21%), Positives = 69/148 (46%), Gaps = 19/148 (12%)
Query: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
+ KE+ S E ++ K + EA+ +LEE++ +EK ++ + L
Sbjct: 845 REKEMASMKEEF-----TRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL- 898
Query: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQ-------R 1905
D + +Q + + A+VK++ +LE+ EE + + A +RKL+ R
Sbjct: 899 ------ADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKR 952
Query: 1906 ELDEATESNEAMGREVNALKSKLRRGNE 1933
++D+ + + +E +A ++K++ E
Sbjct: 953 DIDDLELTLAKVEKEKHATENKVKNLTE 980
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 1435 bits (3714), Expect = 0.0
Identities = 789/1911 (41%), Positives = 1189/1911 (62%), Gaps = 31/1911 (1%)
Query: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
AK V+V K+ + ++I+ ++G +V V+ E G +TV +D + MNPPK+ K+EDMA
Sbjct: 36 AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94
Query: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
+T L+E VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P
Sbjct: 95 MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154
Query: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD S
Sbjct: 155 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGK 214
Query: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKS
Sbjct: 215 MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274
Query: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMFQE 328
R Q + ER++HIFY + + K + LL+ +Y F+S G + +P+ D E
Sbjct: 275 RVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMA 334
Query: 329 TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388
T A+ I+GF+ EE++SI K+ +V+ GN+ FK+++ +QA A K +L +N
Sbjct: 335 TDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLN 394
Query: 389 VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448
D +++ PR+KVG + V K QT +Q AV ALAKA YE++F W++TR+N+ LD T
Sbjct: 395 SADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-TK 453
Query: 449 RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508
+ F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW F
Sbjct: 454 QPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513
Query: 509 IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPK 567
IDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQKPK
Sbjct: 514 IDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPK 570
Query: 568 QLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
+K K E FS+IHYAG VDYN + WL KN DPLND V L S+ K +A L+
Sbjct: 571 VVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTY--- 627
Query: 626 VGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685
+ +SS +K K F+TV L++E L KLMT LR+T P+FVRCIIPN K
Sbjct: 628 -----ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETK 682
Query: 686 RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGK 744
G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D K
Sbjct: 683 TPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSK 742
Query: 745 QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARK 804
+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QA+CRG+L R
Sbjct: 743 KASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRV 802
Query: 805 AFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKT 864
+ K Q+ A+ IQ N A++ +++W W +LF K+KPLL+ E+EM ++E QKT
Sbjct: 803 EYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKT 862
Query: 865 KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 924
K+ K+E + KELE+K L +EKN LQ Q+Q+E + A+AEE +L K +LE +
Sbjct: 863 KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKI 922
Query: 925 HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
E+ R EEEE+ +L A+++K+ + +L++ +++ E K++ EK E K+K L
Sbjct: 923 KEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 982
Query: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
+E+ +D+ KLSKE+K L+E +L EE+K LTK K K E + +LE L+
Sbjct: 983 EEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLE 1042
Query: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIA 1104
+E+K R +LE+ KRKLEGD E D++ +L +L KKE E+ +++++DE A
Sbjct: 1043 QEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQA 1102
Query: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
+ KKI+EL+ I +L E++++ERA+R KAEKQ+ DL ELE + LE+ +T+
Sbjct: 1103 VEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1162
Query: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224
Q EL KRE E L++ L+E T HEA V +R+KHA ++ EL EQ++ +R K L+K
Sbjct: 1163 QVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEK 1222
Query: 1225 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284
K L+ E DL+ + +AK +E + LE QV EL++K + +R +L + +
Sbjct: 1223 EKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRAR 1282
Query: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344
LQ E + L+E + +L++ + + Q+++ + L+EET+ K ++ L+ +
Sbjct: 1283 LQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHD 1342
Query: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1403
+ L++Q +EE E K L+R +S N +++ + K + D E LEE KK+ + ++
Sbjct: 1343 CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQE 1402
Query: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNI 1463
+ E A LEKTK RLQ E++DL++D++ + L+KKQR FD++L+E K
Sbjct: 1403 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK-- 1460
Query: 1464 SSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDLVS 1518
KY E +AE EA +KE+++LS + EE+L+ E L R NK L+ E+ DL
Sbjct: 1461 -QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTE 1517
Query: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R
Sbjct: 1518 QIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577
Query: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
+ +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1578 KIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637
Query: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
E+++ R Q +K+ Q L+DA ++++ E++A L+A++ +L L
Sbjct: 1638 LAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ 1697
Query: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
ER+RK A+ E + +E + + +L + K++LE ++QL+ E+EE ++
Sbjct: 1698 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEK 1757
Query: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
+KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I
Sbjct: 1758 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1817
Query: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K A+
Sbjct: 1818 LEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAK 1877
Query: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
VK KRQ EEAEE+S + RKLQ EL+EA E + +VN L+ K R
Sbjct: 1878 VKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928
Score = 226 bits (575), Expect = 2e-58
Identities = 225/1022 (22%), Positives = 452/1022 (44%), Gaps = 121/1022 (11%)
Query: 836 RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
+L K+K + + +EEE+ A+ + +K ++ + + ++ +LE +++ +EK+ +
Sbjct: 917 QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976
Query: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
+++ TE A +E +L+ +K+ L+E + L+ EED+ L + K+ QQ+ D
Sbjct: 977 KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036
Query: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
LE LE+E+ R L+ K E +K ++ + M++ +L ++ + E IS+L +
Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK 1096
Query: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
+ +E+ L K + ++ I EL ++ E SR + EK + L + + E++ +
Sbjct: 1097 IEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156
Query: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSERAA 1133
+ K+E E Q L++ Q + +R+ +++L E +D+ +
Sbjct: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRV 1216
Query: 1134 RNKAEKQKRDLGEE-----------------LEALKTELEDTLDSTATQQELRAKREQEV 1176
+ K EK+K +L E LE + LED + T++E + + ++
Sbjct: 1217 KQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDL 1276
Query: 1177 TVLKKALDEETRSHEAQVQEM----------RQKHAQAVEELTEQLEQFKRAKANL---- 1222
T + L E + Q+ E +Q Q +EEL QLE+ +AK L
Sbjct: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336
Query: 1223 -------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKKKL 1257
D ++ E+E A R L +A EV E KKKL
Sbjct: 1337 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396
Query: 1258 EAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
++QE + +KC+ E+ + L ++V L +VE + K K +
Sbjct: 1397 AQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVL 1456
Query: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
+ + ++TQ L+ ++ ++ST+L +++ DQL+ +NL++ IS L
Sbjct: 1457 SEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516
Query: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Q+++ K++ + + +E+ K Q +E E + +++ N+++ E+D
Sbjct: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576
Query: 1431 DLVVDLDNQ------------RQLVSNLEKKQRKFDQLLAEEK-------------NISS 1465
+ + D + + S L+ + R + L +K N ++
Sbjct: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1636
Query: 1466 KYADE--RDRAEAEAREKETKALSLARALEEALEAKEEL---ERTNKMLKAEMEDLVSSK 1520
+ A E R+ + KET+ L L AL + KE+L ER +L+AE+E+L ++
Sbjct: 1637 RLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATL 1695
Query: 1521 D--------------DVGKNVHELE-------KSKRALETQMEEMKTQLEELEDELQATE 1559
+ D + V L +K+ LE + ++++++EE+ E + E
Sbjct: 1696 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE 1755
Query: 1560 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 1619
+ K + + A+ + + Q E ++ L++ + + + L DE +Q AL K
Sbjct: 1756 E-KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKK 1813
Query: 1620 K--KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
+ KLE +++LE + ++ K EA+K LRK + ++K+ + E+ R + + +
Sbjct: 1814 QIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDK 1873
Query: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
+ K KS + + +E A ++ E EE E + S N L+ + R + +
Sbjct: 1874 LQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTK 1933
Query: 1738 IA 1739
I+
Sbjct: 1934 IS 1935
Score = 181 bits (460), Expect = 5e-45
Identities = 181/801 (22%), Positives = 367/801 (45%), Gaps = 89/801 (11%)
Query: 1146 EELEALKTELEDTLDSTATQQELRAKREQE-VTVLKKALDEETRSHEAQVQEMRQKHAQA 1204
+E+ +K E + T D A + R + E++ VT+LK+ D +Q Q A +
Sbjct: 850 KEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKND---------LQLQVQSEADS 900
Query: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
+ + E+ EQ L KNK LE + ++ + E+ KK+KLE + EL
Sbjct: 901 LADAEERCEQ-------LIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSEL 953
Query: 1265 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 1324
+ D E A++ + H +N+V+++T + + KL+K+ +L Q T + L
Sbjct: 954 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDL 1013
Query: 1325 QEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDF 1383
Q E K+N+ TK + +LE++ + L+ L++E + + +LER L L +++ D
Sbjct: 1014 QAE-EDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDM 1072
Query: 1384 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
+ + L+E ++ + EI NL + E++ A +L+K LQ +++L +++ +R
Sbjct: 1073 ENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASR 1132
Query: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEA---REKETKALSLARALEEALEAKE 1500
+ EK++ + L E IS + + A+ +++E + L R LEEA E
Sbjct: 1133 AKAEKQRSDLSRELEE---ISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHE 1189
Query: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
M+ A + S ++G+ + L++ K+ LE + E+K + ++L +A
Sbjct: 1190 A------MVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISK 1243
Query: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEE-------KRRQLQRQLHEYETELEDERKQRA 1613
AK LE ++L+ Q +L+ ++E+ + +R +LQ + EY +L+++ +
Sbjct: 1244 AKGNLEKMCRSLEDQVS-ELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVS 1302
Query: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIF- 1672
+ +K+ +++L+ Q + K + L+ + + + E+ + + E+
Sbjct: 1303 QLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQR 1362
Query: 1673 ATAKENEKKAK---SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD 1729
A +K N + A+ E D +Q E+L A++ Q E EE E + + + +L+
Sbjct: 1363 ALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCA---SLEK 1419
Query: 1730 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1789
K+RL+ + L ++E A+ + R + + QK E + +
Sbjct: 1420 TKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK----------QKYEETQAE 1469
Query: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
LE KE RS E+ VK+ ++ ++ LE +L++++K
Sbjct: 1470 LEASQKESRSLSTELF-KVKNVYEESLDQLE----------------------TLRRENK 1506
Query: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE 1909
L++ ++ D EQ +G ++ +L++ ++ E+E I A + + L+
Sbjct: 1507 NLQQ---EISD-------LTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEH 1556
Query: 1910 ATESNEAMGREVNALKSKLRR 1930
+ E+N +KS++ R
Sbjct: 1557 EEGKILRIQLELNQVKSEVDR 1577
Score = 140 bits (352), Expect = 2e-32
Identities = 121/529 (22%), Positives = 242/529 (45%), Gaps = 19/529 (3%)
Query: 1411 KAAAYDKLEKT-KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1469
K+A +K T K Q+ D+L +++L + ++ + L + ++ + AD
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 1470 ERDRAEAEAREK---ETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
+R E + K E K + EE E EL + L+ E +L DD+
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 1527 VHELEKSKRALETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDE 1585
+ ++EK K A E +++ + ++ L++ + + +++ K E + Q L DLQA ++
Sbjct: 964 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLD-----DLQAEED 1018
Query: 1586 QNE---EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642
+ + + +L++Q+ + E LE E+K R AK+KLEGDLK + +++
Sbjct: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQ 1078
Query: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
++L K + ++ + ++ED +A ++ KE + + + L ++ + A AE+
Sbjct: 1079 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQ 1138
Query: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
R E EE++E L + +A + ++ EA +L +LEE EAM +RK
Sbjct: 1139 RSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKK 1198
Query: 1763 -TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
+L ++ + QK E + +L+ + +L S + A K + +LE
Sbjct: 1199 HADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKA-KGNLEKMCRSLED 1257
Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
++++L+ + E++ R T + + E Q++++ + Q + ++++
Sbjct: 1258 QVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEE 1317
Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRR 1930
LK QL EEE++ NA LQ + E E K++L+R
Sbjct: 1318 LKHQL---EEETKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQR 1362
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/358 (23%), Positives = 161/358 (44%), Gaps = 55/358 (15%)
Query: 836 RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
R T+V +Q T + E++++ D L+ K K E +L E+E QL L E
Sbjct: 1591 RNHTRVVETMQSTL-DAEIRSRNDALRVKK----KMEGDLNEME---IQLNHANRLAAES 1642
Query: 896 LQ---------AETELYAE-----AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941
L+ ET+L+ + E+++ +LA +E + ++A +EE +Q
Sbjct: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI----VERRANLLQAEIEELWATLEQT 1698
Query: 942 QAERKKMAQQMLDLEEQLE----------------EEEAARQKLQLEKV-----TAEAKI 980
+ RK Q++LD E+++ E + ++ + ++E+V AE K
Sbjct: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
Query: 981 KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1032
KK + +E+ D + L + +K LE+ + DL L E E+ A K K K
Sbjct: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
Query: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
E+ + ELE ++ E+K E K RK E + Q + + + L+ + K + ++
Sbjct: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
Query: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
++ + ++ Q N L K R+L+ + + +E D + NK + R++ ++ A
Sbjct: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936
Score = 48.1 bits (113), Expect = 8e-05
Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 29/223 (13%)
Query: 839 TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKA-------ENELKELEQKHSQLTEEKNL 891
TK K V++ + E++ E + +E+ +KA ELK+ + + L K
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
Query: 892 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAER--- 945
L++ ++ EAE++ ++ KKQ + ++EAR LE E + Q+ AE
Sbjct: 1789 LEQTVKDLQHRLDEAEQLALK-GGKKQ-----IQKLEARVRELEGEVENEQKRNAEAVKG 1842
Query: 946 -KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN-KLSKERKL 1003
+K +++ +L Q EE+ +LQ +AK+K + + ++Q+N LSK RKL
Sbjct: 1843 LRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902
Query: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046
E L E EE+A NK E+ ++ E
Sbjct: 1903 QHE--------LEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/174 (18%), Positives = 74/174 (42%), Gaps = 8/174 (4%)
Query: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
K ++ + E+AT + QK + + E + KEL K+ + K+ + + +
Sbjct: 840 KPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKE-KNDLQLQVQSEA 898
Query: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
+A EE+ EQ + K Q + K+KE+ + E+E ++ + + K
Sbjct: 899 DSLADAEERCEQLIKNKI-------QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECS 951
Query: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNET 1934
+LK+ +++ E ++ + + ++ TE + + L + + ET
Sbjct: 952 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQET 1005
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 1432 bits (3706), Expect = 0.0
Identities = 783/1903 (41%), Positives = 1173/1903 (61%), Gaps = 23/1903 (1%)
Query: 37 WVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCL 96
+VP +K+ F A I +G +V+ E ENGK VTV +D + + NPPKF K+EDMA LT L
Sbjct: 38 FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96
Query: 97 NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156
+E +VL NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E PPHI++
Sbjct: 97 HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156
Query: 157 IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSIT--GE 213
I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +GKKD + G
Sbjct: 157 ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216
Query: 214 LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIR 273
LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKSR I
Sbjct: 217 LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276
Query: 274 QARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETVE 331
Q + ER +HIFY +++ K ++ D+LL N +Y F+S G V + + D E T
Sbjct: 277 QLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDS 335
Query: 332 AMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTD 391
A ++GF+ EE+ + K+ +++ GN+ FK+++ +QA A K +LMG+N D
Sbjct: 336 AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395
Query: 392 FTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQG 451
+ + PR+KVG + V K Q+ +Q +++ ALAKA YE++F W++TR+N L+ T +
Sbjct: 396 LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454
Query: 452 ASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 511
F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 455 QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514
Query: 512 GLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQLK 570
G+DLQ CI+LIE+P G++++L+EEC FPKATD +F KL G FQKP+ +K
Sbjct: 515 GMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571
Query: 571 DKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
K E FS+IHYAG VDYN WL KN DPLN+ V +L SS K +A L+
Sbjct: 572 GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625
Query: 629 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
A +S K K F+TV L++E L KLMT LR T P+FVRCIIPN K G
Sbjct: 626 -ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPG 684
Query: 689 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQAC 747
+D LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL AIP+G F+D ++
Sbjct: 685 VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGT 744
Query: 748 ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
++ +L++D N Y+ G +K+FF+ G+L LEE RD +++ +I QA RG L R F
Sbjct: 745 EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFK 804
Query: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
K ++ A+ VIQ N A++ ++NW W +L+ K+KPLL+ E+EM ++E + KE
Sbjct: 805 KIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKET 864
Query: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
+K+E KELE+K L +EKN LQ Q+QAE + +AEE +L K +LE + EM
Sbjct: 865 LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEM 924
Query: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
RLE+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K L +E+
Sbjct: 925 NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984
Query: 988 LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1047
+D+ KL+KE+K L+E +L EE+K +L+K K K E + +LE L++E+
Sbjct: 985 AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK 1044
Query: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
K R +LE+ KRKLEGD E I DL+ +L+ +L KKE ++ ++++DE
Sbjct: 1045 KVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL 1104
Query: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
KK++E + I +L+E+L++ER AR K EK + DL ELE + LE+ +T+ Q E
Sbjct: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164
Query: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L+K K
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224
Query: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
+ E D+ + + +AK +E + LE Q E + K + +R+ + + KLQ
Sbjct: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284
Query: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
E + L E E +L + S + Q++D + L+EE + K ++ L+ + +
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
Query: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLTQ 1406
L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +++ +
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
Query: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
E A LEKTK+RLQ E++DL+VD++ + L+KKQR FD++LAE K +
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
Query: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
E + ++ EAR T+ L A EE+LE E +R NK L+ E+ DL + GKN
Sbjct: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524
Query: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
VHELEK ++ LE + E+++ LEE E L+ E LR ++ +K + ER L +DE+
Sbjct: 1525 VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1584
Query: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
E+ +R QR + +T L+ E + R KKK+EGDL ++E+Q A + EA KQ
Sbjct: 1585 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644
Query: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
++ LQ+ +KD Q +L+DA + D++ E++ L+A+L +L+ + ER+RK A
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704
Query: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
+ E E +E + S +L ++K+++E+ + QL+ E+EE ++ +KA A
Sbjct: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764
Query: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
++ EL E+ T+ E ++ +E+ K+L+ +L E E K + LEA++ +L
Sbjct: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1824
Query: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
E ++E E + + K +++ ++++KE+ Q E+++K + ++ +K +VK KRQ
Sbjct: 1825 EGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQA 1884
Query: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
EEAEE++ + RK+Q ELDEA E + +VN L++K R
Sbjct: 1885 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
Score = 233 bits (593), Expect = 2e-60
Identities = 206/929 (22%), Positives = 419/929 (45%), Gaps = 59/929 (6%)
Query: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
K+K +S +E E+ KEE R +++ K E + E++ L + +L++Q+
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGR--IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQ 894
Query: 1087 KKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
+++ L A R D I K K++E+ + D +E++++E A+ KR L +
Sbjct: 895 AEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLED-EEEMNAELTAK------KRKLED 947
Query: 1147 ELEALKTELED---TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQ 1203
E LK +++D TL ++ + + +T LDE + + +++ H Q
Sbjct: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 1204 AVEELTEQLEQFKRAKAN-LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQ 1262
A+++L Q + K N L K+K LE++ DL G L + + ++E K+KLE ++
Sbjct: 1008 ALDDL-----QVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1062
Query: 1263 ELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322
Q D E + +L +K+ K + ++ + + + A++L K + +++++ +E
Sbjct: 1063 LTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEE 1122
Query: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382
L+ E + V E+ R+ L +L+E E LE ++Q+ +KK+ +
Sbjct: 1123 ELEAERTARAKV-------EKLRSDLSRELEEISE---RLEEAGGATSVQIEMNKKREAE 1172
Query: 1383 FASTVEALEEG-----------KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDD 1431
F LEE +K+ + L +Q + KLEK K+ + ELDD
Sbjct: 1173 FQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDD 1232
Query: 1432 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK-ETKALSLAR 1490
+ +++ + +NLEK R + A E + + A R K +T+ LAR
Sbjct: 1233 VTSNMEQIIKAKANLEKVSRTLEDQ-ANEYRVKLEEAQRSLNDFTTQRAKLQTENGELAR 1291
Query: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
LEE +L R +MEDL ++ GK + L + ++ + ++ Q EE
Sbjct: 1292 QLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEE 1351
Query: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
+ + + + + ++E D R E+ EE +++L ++L + E +E
Sbjct: 1352 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNA 1411
Query: 1611 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1670
+ + K +L+ +++DL + E + L + ++F + L + + +E
Sbjct: 1412 KCSSLEKTKHRLQNEIEDLMVDV-------ERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
Query: 1671 IFATAKENEKKAKSLEADLMQLQ-------EDLAAAERARKQADLEKEELAEELASSLSG 1723
+ + ++K+A+SL +L +L+ E L +R K E +L E+L
Sbjct: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524
Query: 1724 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1783
+ L+ +++LE +L+ LEE + ++E ++ +A + Q+ E+ ER A+K+
Sbjct: 1525 VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKD 1582
Query: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFK--STIAALEAKIAQLEEQVEQEAREKQAAT 1841
E Q + + S ++ +S+ + +E + ++E Q+ R A
Sbjct: 1583 EEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1642
Query: 1842 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1901
K +K LK+ +Q++D + + KE R L+ +LEE ++ +R+
Sbjct: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRK 1702
Query: 1902 KLQRELDEATESNEAMGREVNALKSKLRR 1930
++EL E +E + + + +L ++ ++
Sbjct: 1703 LAEQELIETSERVQLLHSQNTSLINQKKK 1731
Score = 229 bits (584), Expect = 2e-59
Identities = 240/1034 (23%), Positives = 468/1034 (45%), Gaps = 135/1034 (13%)
Query: 836 RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
+L KVK + + EEEM A+ + +K ++ + + ++ +LE +++ +EK+ +
Sbjct: 916 QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 975
Query: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
+++ TE A +E+ +L +K+ L+E + L+ EED+ L + K+ QQ+ D
Sbjct: 976 KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD 1035
Query: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER--ISDLT 1012
LE LE+E+ R L+ K E +K ++ I MD +N+KL E KL ++ I+
Sbjct: 1036 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESI--MDLENDKLQLEEKLKKKEFDINQQN 1093
Query: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072
+ + +E+ A L K ++++ I ELE L+ E +R ++EKL+ L + + E++
Sbjct: 1094 SKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1153
Query: 1073 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSER 1131
+ + K+E E Q L++ Q +R+ +++L E +D+ +
Sbjct: 1154 EAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQ 1213
Query: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS-- 1189
+ K EK+K + EL+ + + +E + + A +++ E + + L+E RS
Sbjct: 1214 RVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLN 1273
Query: 1190 ----------------------HEAQVQEMRQ---KHAQAVEELTEQLEQFKRAKANL-- 1222
EA + ++ + + Q +E+L QLE+ +AK L
Sbjct: 1274 DFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAH 1333
Query: 1223 ---------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKK 1255
D ++ E+E A RVL +A EV E KK
Sbjct: 1334 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 1393
Query: 1256 KL-------EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
KL E V+ + +KCS E+ + L +++ L +VE + K K
Sbjct: 1394 KLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 1453
Query: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1368
+A + +++Q L+ ++ ++ST+L +L+ + L+ +NL+ IS
Sbjct: 1454 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 1513
Query: 1369 LNIQLSDSKKKLQDFASTVEALE--------------------EGK-KRFQKEIENLTQQ 1407
L QL + K + + + LE EGK R Q E + +
Sbjct: 1514 LTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 1573
Query: 1408 YEEKAAAYDK-LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
E K A D+ +E+ K Q+ +D L LD + + + + + ++K + L E I
Sbjct: 1574 IERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDL-NEMEIQLS 1632
Query: 1467 YADERDRAEAEAREKETKAL--SLARALEEALEAKEEL-------ERTNKMLKAEMEDLV 1517
+A+ R AEA+ + K ++L L++A+ A ++L ER N +L+AE+E+L
Sbjct: 1633 HAN-RMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELR 1691
Query: 1518 SSKD--------------DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ------- 1556
+ + + + V L +L Q ++M++ L +L+ E++
Sbjct: 1692 AVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECR 1751
Query: 1557 -ATEDAKLRL-EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
A E AK + + M A + + E+D A E+ ++ +++ + + + L DE +Q AL
Sbjct: 1752 NAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKNMEQTIKDLQHRL-DEAEQIAL 1807
Query: 1615 AAAAKK--KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD--FQRELEDARASRDE 1670
K+ KLE +++LE + ++ K E++K +RK + ++K+ +Q E + R +
Sbjct: 1808 KGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQ 1867
Query: 1671 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDE 1730
+ + KA +A+ + Q + ++ + Q +L++ E ++A S N L+ +
Sbjct: 1868 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV--NKLRAK 1925
Query: 1731 KRRLEARIAQLEEE 1744
R + A+ +EE
Sbjct: 1926 SRDIGAKQKMHDEE 1939
Score = 134 bits (337), Expect = 9e-31
Identities = 141/614 (22%), Positives = 280/614 (45%), Gaps = 51/614 (8%)
Query: 1328 TRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
TR + +L ++E ++ + ++ D + + N+ + N K++ +
Sbjct: 788 TRMQAQARGQLMRIEFKK--IVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSA 845
Query: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
E E+ ++E + + E+ A +LE+ L QE +DL + + ++ NL
Sbjct: 846 ET-EKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD---NLN 901
Query: 1448 KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNK 1507
+ + DQL+ +++ + EA+ KE + LE+ E EL +
Sbjct: 902 DAEERCDQLI-------------KNKIQLEAKVKE-----MNERLEDEEEMNAELTAKKR 943
Query: 1508 MLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL-QATEDAKLRLE 1566
L+ E +L DD+ + ++EK K A E +++ + ++ L++ + + T++ K E
Sbjct: 944 KLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQE 1003
Query: 1567 VNMQALKGQFERDLQARDEQNE---EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
+ QAL DLQ +++ + + +L++Q+ + E LE E+K R AK+KLE
Sbjct: 1004 AHQQALD-----DLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLE 1058
Query: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
GDLK + + + ++L+K + + ++ED + ++ KEN+ + +
Sbjct: 1059 GDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIE 1118
Query: 1684 SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEE 1743
LE +L + A E+ R E EE++E L + + + ++ EA ++
Sbjct: 1119 ELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1178
Query: 1744 ELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHE 1803
+LEE EA + +RK + A+ ++ EL + Q+ +Q+LE++ E + +L +
Sbjct: 1179 DLEEATLQHEATAAALRK--KHADSVA-ELGEQIDNLQR---VKQKLEKEKSEFKLELDD 1232
Query: 1804 MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQ---KDKKLK----EILL 1856
+ ++ K+ A LE LE+Q + + + A +SL + KL+ E+
Sbjct: 1233 VTSNMEQIIKAK-ANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELAR 1291
Query: 1857 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEA 1916
Q+E++ + Q +++ LKRQL EEE + NA LQ + E
Sbjct: 1292 QLEEKEALISQLTRGKLSYTQQMEDLKRQL---EEEGKAKNALAHALQSARHDCDLLREQ 1348
Query: 1917 MGREVNALKSKLRR 1930
E A K++L+R
Sbjct: 1349 YEEETEA-KAELQR 1361
Score = 100 bits (249), Expect = 1e-20
Identities = 86/376 (22%), Positives = 173/376 (46%), Gaps = 45/376 (11%)
Query: 1566 EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGD 1625
E M +K +F R ++ E++E +R++L+ ++ L E+ L A+ + +
Sbjct: 848 EKEMATMKEEFGR-IKETLEKSEARRKELEEKM----VSLLQEKNDLQLQVQAE---QDN 899
Query: 1626 LKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSL 1685
L D E + D IK + + L+A++K+ LED E+ A ++ E + L
Sbjct: 900 LNDAEERCDQLIKNKIQ-------LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSEL 952
Query: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEEL 1745
+ D+ L+ LA E+ + + + + L EE+A L EK+ L+ Q ++L
Sbjct: 953 KKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDL 1012
Query: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEME 1805
+ E+ + ++S K QQ + L L E+ E A+++LE K + + ++E
Sbjct: 1013 QVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1072
Query: 1806 GAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMA 1865
+ Q+E++ ++K+ + Q++ K +EDE+ +A
Sbjct: 1073 ND-------------------KLQLEEKLKKKEF---DINQQNSK-------IEDEQVLA 1103
Query: 1866 EQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALK 1925
Q +++ ++ AR+++L+ +LE ++ R L REL+E +E E G +++
Sbjct: 1104 LQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG-GATSVQ 1162
Query: 1926 SKLRRGNETSFVPSRR 1941
++ + E F RR
Sbjct: 1163 IEMNKKREAEFQKMRR 1178
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 1424 bits (3687), Expect = 0.0
Identities = 781/1913 (40%), Positives = 1186/1913 (61%), Gaps = 32/1913 (1%)
Query: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
AK V+V K+ + A ++ +G +V + E G VTV +D + MNPPK+ K+EDMA
Sbjct: 34 AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92
Query: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152
Query: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212
Query: 212 GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 272
Query: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
KSR Q + ER++HIFY +++ K ++ LL+ ++ F+S G + +P+ D E
Sbjct: 273 KSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEEL 332
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
T A+ I+GF+ +E+++I K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 333 MATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTS 392
Query: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
+N D +S+ PR+KVG + V K QT +Q AV ALAKA YE++F W++TR+N+ LD
Sbjct: 393 LNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLD- 451
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 512 EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568
Query: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
PK K K E FS++HYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 569 PKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA- 627
Query: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
Q A+ K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 628 ------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681
Query: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 682 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741
Query: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
K+A ++ ++E+D Y+ G +K+FF+ G+L LEE RD K+ +I QA+CRG+L
Sbjct: 742 SKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLM 801
Query: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
R F K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++E +
Sbjct: 802 RVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861
Query: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEA 921
Query: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 922 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
Query: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGS 1041
Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
L++E+K +LE+ KRKLEGD E D + +L +L KKE E+ +++DE
Sbjct: 1042 LEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDE 1101
Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1102 QALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161
Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKL 1221
Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
+K K L+ E DLA + + +AK E + LE Q+ E+++K + +R EL+ +
Sbjct: 1222 EKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQK 1281
Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
+L E + L+E + +L++ + + Q+++ + L+EET+ K ++ L+
Sbjct: 1282 ARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSAR 1341
Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1342 HDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
++ + E + LEKTK RLQ E++DL++D++ L+KKQR FD++LAE K
Sbjct: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWK 1461
Query: 1462 NISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDL 1516
KY E +AE EA +KE+++LS + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1462 ---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDL 1516
Query: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
+ GK++HELEK K+ L+ + E++T LEE E L+ E LR+++ + +K +
Sbjct: 1517 TEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI 1576
Query: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
+R + +DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A
Sbjct: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636
Query: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
+ EA++ LR Q +KD Q L+DA +D++ E++A ++A++ +L+ L
Sbjct: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASL 1696
Query: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
ER RK A+ E + +E + + +L + K++LE I+Q++ E+E+
Sbjct: 1697 ERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAE 1756
Query: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1816
++ +KA A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I
Sbjct: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1816
Query: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
LEA++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K
Sbjct: 1817 QKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1876
Query: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
+VK KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R
Sbjct: 1877 TKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
Score = 97.8 bits (242), Expect = 9e-20
Identities = 85/366 (23%), Positives = 166/366 (45%), Gaps = 44/366 (12%)
Query: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADS---AIKG 1639
K + ++++ + E E +++ A A +K+LE + DL+LQ + A+
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALAD 904
Query: 1640 REEAIKQLRK----LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
EE QL K L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
Query: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
+ K QQ + L L E+ E A+++LE G +K +ST
Sbjct: 1025 TKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLE--------------GDLKLAQEST 1070
Query: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
+ K +Q+ ++ LK+K+ ++ + ++EDE+ +A Q +++ ++
Sbjct: 1071 MDTENDK-----QQLNEK----------LKKKEFEMSNLQGKIEDEQALAIQLQKKIKEL 1115
Query: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1174
Query: 1936 FVPSRR 1941
F RR
Sbjct: 1175 FQKMRR 1180
Score = 74.7 bits (182), Expect = 8e-13
Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)
Query: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
+++ E E E+Q +Q AE L+ L L + + L + ++ + +L +
Sbjct: 1619 KKKMEGDLNEMEIQLNHANRQAAE-ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAM 1677
Query: 909 MRVRLAAKKQELEEILHEMEA-----RLEEEE-----DRGQQLQAERKKMAQQMLDLEEQ 958
+ R + E+EE+ +E ++ E+E +R Q L + + LE
Sbjct: 1678 VERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
Query: 959 LEEEEAARQKLQLEKVTAEAKIKK-------LEDEILVMDDQNNKLSKERKLLEERISDL 1011
+ + + + + E AE K KK + +E+ D + L + +K +E+ + DL
Sbjct: 1738 ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1797
Query: 1012 TTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
L E E+ A K K K E+ + ELE ++ E+K E K RK E + Q
Sbjct: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857
Query: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
+ + I L+ + K + +++A + ++ Q N L K R+L+ + + +E D
Sbjct: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIA 1917
Query: 1131 RAARNKAEKQKRDL 1144
+ NK + R++
Sbjct: 1918 ESQVNKLRVKSREV 1931
Score = 72.4 bits (176), Expect = 4e-12
Identities = 64/273 (23%), Positives = 122/273 (44%), Gaps = 16/273 (5%)
Query: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
L V R+ MQA+ +EL+ + ER ++ K EQ+ +E LL Q T L
Sbjct: 1675 LAMVERRANLMQAEVEELRASLERTERGR---KMAEQELLDASERVQLLHTQ---NTSLI 1728
Query: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
+++ ++ + E+E+I+ E E++ ++ + MA+++ +EQ
Sbjct: 1729 NTKKKLETDISQIQGEMEDIVQEAR----NAEEKAKKAITDAAMMAEELK--KEQDTSAH 1782
Query: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
R K +E+ + +++ E E L + ++ K LE R+ +L + + E++
Sbjct: 1783 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELESEVESEQKHNV 1838
Query: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
Query: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIREL 1116
+ K + EL+ A R D +Q N K RE+
Sbjct: 1899 KFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 1424 bits (3686), Expect = 0.0
Identities = 780/1908 (40%), Positives = 1182/1908 (61%), Gaps = 25/1908 (1%)
Query: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
AK +V K+ + IK + +V VE E+ + + V +D+ MNPPKF ++EDMA
Sbjct: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
Query: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
LT LNE +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V+ Y+GKKR E P
Sbjct: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
Query: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK--GKKDTS 209
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ KKD+
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212
Query: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEKS
Sbjct: 213 MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272
Query: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQ 327
R Q + ER++HIFY +++ K ++ +LLL N +Y F+S G + + + D E
Sbjct: 273 RVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASIDDAEELL 331
Query: 328 ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
T A+ I+GF+ EE+ + K+ +V+ GN+ FK+++ +QA A K +LMG+
Sbjct: 332 ATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGL 391
Query: 388 NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-K 446
N +D +++ PR+KVG + V K QT +Q AV AL+K+ YE+LF W++TR+N+ LD K
Sbjct: 392 NSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTK 451
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
RQ F+G+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452 LPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 510 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 566
Query: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
PK +K + E FS+IHYAG VDY+ S WL KN DPLN+ V L SS++ +A L+
Sbjct: 567 PKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATF- 625
Query: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
+S +K K F+TV L++E L KLM+ LR T P+FVRCIIPN
Sbjct: 626 -------ATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNE 678
Query: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
K G ++ LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L A+AIP+G F+D
Sbjct: 679 TKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFID 738
Query: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
K+AC ++ ++++D Y+ G +K+FF+ G+L LEE RD ++ +I QA+CRG+L
Sbjct: 739 SKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLM 798
Query: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
R F K Q+ ++ IQ N +++ +++W W +LF K+KPLL+ E+EM ++E Q
Sbjct: 799 RVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 858
Query: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
KTK+ K+E + KELE+K L +EKN LQ Q+QAE+E +AEE +L K +LE
Sbjct: 859 KTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEA 918
Query: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 919 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 978
Query: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
L +E+ +D+ KL++E+K L+E +L EE+K +L K K+K E + +LE
Sbjct: 979 LTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS 1038
Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
L++E+K R +LE+ KRKLEGD E I DL+ +L +L KK+ E ++++DE
Sbjct: 1039 LEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDE 1098
Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
KKI+EL+ I +L+E++++ERA R K EKQ+ D ELE L LE+ T
Sbjct: 1099 QTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT 1158
Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
+TQ EL KRE E L++ L+E T HEA V +R+KHA +V EL EQ++ +R K L
Sbjct: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218
Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
+K K + E DL+ + + ++K +E + LE Q+ E + K + +R+ +EL +
Sbjct: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 1278
Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
+LQ E ++ L E E +L++ + + Q ++ + L+EE + K ++ L+
Sbjct: 1279 SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSR 1338
Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
+ + L++Q +EE E K L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1339 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1398
Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
++ +Q E A LEKTK RLQ E++DL+VD++ L + L+KKQR FD++LAE K
Sbjct: 1399 QDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWK 1458
Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
+ E + + E+R T+ L A EEAL+ E ++R NK L+ E+ DL
Sbjct: 1459 TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA 1518
Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
+ GK +HELEKS++ +E + +++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1519 ENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIA 1578
Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
+DE+ E+ +R QR + ++ L+ E + R A KKK+EGDL ++E+Q A +
Sbjct: 1579 EKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAA 1638
Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
E +K LR +Q Q+KD Q L+DA ++++ E++A L+A++ +L+ L ER
Sbjct: 1639 ETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTER 1698
Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
ARK A+ E + E + + +L K++LE + QL+ E+E+ + ++ +K
Sbjct: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758
Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
A A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LE
Sbjct: 1759 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818
Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
+I +LE ++E E ++ + K L++ ++++KE+ Q E++RK + ++ +K +VK
Sbjct: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878
Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
KRQ EEA+E++ RK Q EL+EA E + +VN L++K R
Sbjct: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
Score = 202 bits (515), Expect = 2e-51
Identities = 192/880 (21%), Positives = 376/880 (42%), Gaps = 75/880 (8%)
Query: 1106 KNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQ 1165
K L K E E ++ ++E+ + K+E ++++L E+L L E D
Sbjct: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDL------- 888
Query: 1166 QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKN 1225
+L+ + E E LD E R + ++ Q A+ ++E+TE+ E + A L
Sbjct: 889 -QLQVQAESE-----NLLDAEERCDQL-IKAKFQLEAK-IKEVTERAEDEEEINAELTAK 940
Query: 1226 KQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL 1285
K+ LE E ++L ++ L +VE +K E +V+ L + S + A+L + L
Sbjct: 941 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKAL 1000
Query: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
Q + L E K L K + L Q++D + L++E + ++++ R+LE +
Sbjct: 1001 QEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDL 1060
Query: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405
Q+ + + KQ L+ + + + + K++D + ++ K Q IE L
Sbjct: 1061 KLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELE 1120
Query: 1406 QQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSN-LEKKQRKFDQLLAEEKNIS 1464
++ E + A K EK ++ +EL++L L+ + S +E +++ + L +++
Sbjct: 1121 EEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLE 1180
Query: 1465 SKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
A ++ L ++ K++LE+ K E++DL SS + V
Sbjct: 1181 EATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 1240
Query: 1525 KNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE------- 1577
K+ LEK R LE Q+ E + + EE++ L K RL+ L Q E
Sbjct: 1241 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVS 1300
Query: 1578 ---RDLQARDEQNEEKRRQLQRQ---------------------LHEYETELEDERK-QR 1612
R QA +Q EE +RQL+ + +YE E E + + QR
Sbjct: 1301 QLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQR 1360
Query: 1613 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIF 1672
AL+ A + + K AI+ EE + +KL +++D + ++E A +
Sbjct: 1361 ALSKANSEVAQWRTK----YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLE 1416
Query: 1673 ATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 1732
T + + + + L D+ + AA ++ ++ D E + S + A E R
Sbjct: 1417 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 1476
Query: 1733 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
L + +L+ EE +E + + Q+ L+ ++A T + E +R+Q+E
Sbjct: 1477 SLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIEL 1536
Query: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
+ +++ L E E A++ + ++ I ++ ++ Q++ +++++ EK + LK+ ++
Sbjct: 1537 EKADIQLALEEAEAALEHE-EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTV 1595
Query: 1853 EILLQVED----ERKMAEQYKEQAEKG----NARVKQLKRQLEEAEEESQRINANRRKLQ 1904
E + D R A + K++ E ++ RQ E + + + + Q
Sbjct: 1596 ETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQ 1655
Query: 1905 RELDEATESNEAMGR--------------EVNALKSKLRR 1930
LD+A E + EV L++ L +
Sbjct: 1656 LHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQ 1695
Score = 131 bits (330), Expect = 6e-30
Identities = 124/538 (23%), Positives = 251/538 (46%), Gaps = 51/538 (9%)
Query: 850 QEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAETELYAEA 906
Q E + AK L+KTK+R Q + E+ + ++E+ +S ++K +++ AE + E
Sbjct: 1404 QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEE 1463
Query: 907 EEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962
+ + + K+ + L L +++ EE D+ + ++ E K + Q++ DL EQ+ E
Sbjct: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 1523
Query: 963 ----EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
E +R++++LEK + +++ E ++ + K+ + + L + S++ +AE+
Sbjct: 1524 IHELEKSRKQIELEKADIQLALEEAE---AALEHEEAKILRIQLELTQVKSEIDRKIAEK 1580
Query: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
+E+ + +LK ++ + ++ L E +SR E +LK+K+EGD ++ Q++ Q
Sbjct: 1581 DEE---IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQA 1637
Query: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA------ 1132
AE L + +L+ LDD + + + +++ +E + LQ +++ RA
Sbjct: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697
Query: 1133 -ARNKAEKQ---------------------KRDLGEELEALKTELEDTLDSTATQQELRA 1170
AR AE++ K+ L +L L++E+ED +E
Sbjct: 1698 RARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK 1757
Query: 1171 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK-QTL 1229
K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K + Q L
Sbjct: 1758 KAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 1230 EKENADLAGELRVLGQAKQEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
E +L EL G+ K+ E K +K E +V+EL + + + L D V KLQ
Sbjct: 1817 ETRIRELEFELE--GEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQV 1874
Query: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
+V+S EA+ +A +L++ +E Q + K R R
Sbjct: 1875 KVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932
Score = 112 bits (281), Expect = 3e-24
Identities = 105/498 (21%), Positives = 217/498 (43%), Gaps = 63/498 (12%)
Query: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
L A +E KEE ++T K E+ + + ++ + + L + K L+ Q++
Sbjct: 841 LKSAETEKEMATMKEEFQKT----KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAES 896
Query: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
L + E+ AK +LE ++ + + E + + E +KR+ L+ + E + ++
Sbjct: 897 ENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRK-LEDECSELKKDI 955
Query: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-RKLQAQMKDFQRELEDA 1664
+D A K E +K+L + + G +E I +L R+ +A + Q+ L+D
Sbjct: 956 DDLELTLAKVEKEKHATENKVKNLTEE----LSGLDETIAKLTREKKALQEAHQQALDDL 1011
Query: 1665 RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1724
+A D++ + K K LE + L+ L ++ R + K +L +L +
Sbjct: 1012 QAEEDKVNSLNKTKSK----LEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI 1067
Query: 1725 NALQDEKRRLEARI-------AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
L+++K++L+ R+ QL+ ++E+EQ ++++ + E+L E+ ER
Sbjct: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127
Query: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK------------------------ 1813
+T K E R R+ +EL +L E G ++ +
Sbjct: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE 1187
Query: 1814 STIAALEAK----IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVE-------DER 1862
+ +AAL K +A+L EQ++ R KQ K + ++ ++ +E +
Sbjct: 1188 AMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLE 1247
Query: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDE-------ATESNE 1915
K+ ++Q + + ++++R L E + R+ +L R+L+E + S +
Sbjct: 1248 KICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQ 1307
Query: 1916 AMGREVNALKSKLRRGNE 1933
A ++ LK +L N+
Sbjct: 1308 AFTQQTEELKRQLEEENK 1325
Score = 79.0 bits (193), Expect = 4e-14
Identities = 75/314 (23%), Positives = 138/314 (43%), Gaps = 21/314 (6%)
Query: 849 RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL------ 902
+++ E E E+Q + +Q AE LK L QL + + L + L+ + +L
Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAET-LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674
Query: 903 --------YAEAEEMRVRLA----AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
AE EE+R L A+K +E+L E R++ + L +KK+
Sbjct: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQELLDSNE-RVQLLHTQNTSLIHTKKKLET 1733
Query: 951 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
++ L+ ++E+ + + + A + +E+ D + L + +K LE+ + D
Sbjct: 1734 DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1793
Query: 1011 LTTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
L L E E+ A K K K E+ I ELE L+ E+K E K RK E +
Sbjct: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
Query: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
Q + + + L+ + K + ++++ + ++ Q N L K R+ + + + +E D
Sbjct: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
Query: 1130 ERAARNKAEKQKRD 1143
+ NK + RD
Sbjct: 1914 AESQVNKLRAKTRD 1927
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 1423 bits (3683), Expect = 0.0
Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%)
Query: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
AK V+V K+ F +I+ +G +V V+ E G +TV D + MNPPK+ K+EDMA
Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
Query: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
Query: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
Query: 209 -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
Query: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
KSR + Q + ER++HIFY + + K ++ LL+ +Y F+S G + + + D E
Sbjct: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
T A+ I+GF+ EE++SI K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 333 MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392
Query: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
+N D +++ PR+KVG + V K QT EQ AV ALAKA YE++F W++ R+N+ LD
Sbjct: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 512 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568
Query: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
PK +K K E F++IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 569 PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628
Query: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
G + K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 629 TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683
Query: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743
Query: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QA CRG+LA
Sbjct: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803
Query: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
R + + ++ A+ IQ N +++ +++W W +LF K+KPLL+ E+EM ++E Q
Sbjct: 804 RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863
Query: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
K K+ K+E + KELE+K L +EKN LQ Q+QAE E A+AEE +L K +LE
Sbjct: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923
Query: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 924 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983
Query: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 984 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043
Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
L++E+K R +LE+ KRKLEGD E I D++ + +L +L KKE E+ ++++DE
Sbjct: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
+K K ++ E DLA + + +AK +E + LE Q+ EL+SK + +R +L +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
+LQ E + L+E E +L++ + + Q+++ + L+EE + K ++ L+
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
+ + L++Q +EE E+K L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403
Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
+ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LAE K
Sbjct: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463
Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
+ E + ++ EAR T+ + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523
Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583
Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
+DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643
Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
EA++ R Q +KD Q L+DA S++++ E++A L+A++ +L+ L ER
Sbjct: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ +K
Sbjct: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763
Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I LEA
Sbjct: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823
Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K A+VK
Sbjct: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883
Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R
Sbjct: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
Score = 235 bits (599), Expect = 4e-61
Identities = 225/1025 (21%), Positives = 456/1025 (44%), Gaps = 121/1025 (11%)
Query: 836 RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
+L K+K + + EEE+ A+ + +K ++ + + ++ +LE +++ +EK+ +
Sbjct: 920 QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 979
Query: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
+++ TE A +E +L +K+ L+E + L+ EED+ L + K+ QQ+ D
Sbjct: 980 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039
Query: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
LE LE+E+ R L+ K E +K ++ I+ ++++ +L ++ K E IS+L +
Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Query: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
+ +E+ L K + ++ I ELE ++ E SR + EK + L + + E++ +
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159
Query: 1075 Q-AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSERA 1132
A A+++M K+E E Q L++ Q +R+ +++L E +D+ +
Sbjct: 1160 GGATSAQIEMN-KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218
Query: 1133 ARNKAEKQKRDLGEELEALKTE-----------------LEDTLDSTATQQELRAKREQE 1175
+ K EK+K ++ E++ L + LED L +++E + + +
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
Query: 1176 VTVLKKALDEETRSHEAQVQEM----------RQKHAQAVEELTEQLEQFKRAKANL--- 1222
+T + L E+ Q+ E +Q Q +EEL QLE+ +AK L
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 1223 --------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKKK 1256
D ++ E+E A R L +A EV E KKK
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
Query: 1257 L-------EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
L E V+ + +KC+ E+ + L ++V L +VE + K K
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458
Query: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
+A + ++T L+ ++ ++ T+L +++ DQL+ +NL++ IS L
Sbjct: 1459 LAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1518
Query: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Q+++ K++ + + +E+ K Q +E E + +++ N+++ E+
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Query: 1430 DDLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL 1488
D + + D + QL N + L E + + + E + E E +
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638
Query: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
R EAL + K + ++D + S++D+ + + +E+ L+ ++EE++ L
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698
Query: 1549 EELE--------DELQATE-------------DAKLRLEVNMQALKGQFERDLQ-ARDEQ 1586
E+ E + L A+E + K +LE ++ ++G+ E LQ AR+ +
Sbjct: 1699 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAE 1758
Query: 1587 NEEKR----------------------RQLQRQLHEYETELE---DERKQRALAAAAKK- 1620
+ K+ ++++ + + +L+ DE +Q AL K+
Sbjct: 1759 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1818
Query: 1621 -KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
KLE +++LE + +S K EA+K LRK + ++K+ + E+ R + + + +
Sbjct: 1819 QKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1878
Query: 1680 KKAKSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
K KS +A+ + Q + A+ + Q +LE+ E ++A S N L+ + R + +
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTK 1936
Query: 1738 IAQLE 1742
+ E
Sbjct: 1937 VISEE 1941
Score = 182 bits (462), Expect = 3e-45
Identities = 185/809 (22%), Positives = 371/809 (45%), Gaps = 92/809 (11%)
Query: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
+ EK+ + EE + +K EL S A ++EL E+ VT+LK+ D +Q
Sbjct: 850 ETEKEMATMKEEFQKIKDELAK---SEAKRKELE---EKMVTLLKEKND---------LQ 894
Query: 1196 EMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEKENADLAGELRVLGQAKQEVEHKK 1254
Q A+ + + E+ +Q + K L+ K K+ E+ + + E+ KK
Sbjct: 895 LQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDE--------EEINAELTAKK 946
Query: 1255 KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
+KLE + EL+ D E A++ + H +N+V+++T + + KL K+ +L
Sbjct: 947 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQ 1006
Query: 1315 SQLQDTQELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Q T + LQ E K+N TK + +LE++ + L+ L++E + + +LER L L
Sbjct: 1007 EAHQQTLDDLQAE-EDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1065
Query: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
+++ + D + + L+E K+ + EI NL + E++ A +L+K LQ +++L
Sbjct: 1066 KLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELE 1125
Query: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
+++ +R + EK++ + L E IS + + A+ + + +
Sbjct: 1126 EEIEAERASRAKAEKQRSDLSRELEE---ISERLEEAGGATSAQIEMNKKREAEFQKMRR 1182
Query: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
+ EA + E T L+ + D V+ ++G+ + L++ K+ LE + EMK ++++L
Sbjct: 1183 DLEEATLQHEATAATLRKKHADSVA---ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE-------KRRQLQRQLHEYETELE 1606
++ AK LE + L+ Q +L++++E+ + +R +LQ + E+ +L+
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLS-ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298
Query: 1607 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1666
++ + + K+ +++L+ Q + IK + L+ + + + E+ +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358
Query: 1667 SRDEIF-ATAKENEKKAK---SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLS 1722
S+ E+ A +K N + A+ E D +Q E+L A++ Q + + AEE +++
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQ----RLQAAEEHVEAVN 1414
Query: 1723 GRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1781
+ A L+ K+RL+ + L ++E A+ + R + + Q
Sbjct: 1415 AKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK----------Q 1464
Query: 1782 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1841
K E +LE KE RS G K K+ A E + QLE
Sbjct: 1465 KCEETHAELEASQKEARSL-----GTELFKIKN---AYEESLDQLE-------------- 1502
Query: 1842 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1901
+LK+++K L++ ++ D EQ +G R+ +L++ ++ E+E + A
Sbjct: 1503 -TLKRENKNLQQ---EISD-------LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALE 1551
Query: 1902 KLQRELDEATESNEAMGREVNALKSKLRR 1930
+ + L+ + E+N +KS++ R
Sbjct: 1552 EAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Score = 141 bits (356), Expect = 6e-33
Identities = 123/560 (21%), Positives = 255/560 (45%), Gaps = 36/560 (6%)
Query: 1378 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
K L A T + + K+ FQK + + + A +LE+ L +E +DL + +
Sbjct: 843 KPLLKSAETEKEMATMKEEFQK----IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ 898
Query: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497
+ + +++ E++ DQL+ + + +K + +RAE E E
Sbjct: 899 AEAEGLADAEER---CDQLIKTKIQLEAKIKEVTERAEDEE------------------E 937
Query: 1498 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL-Q 1556
EL + L+ E +L DD+ + ++EK K A E +++ + ++ L++ + +
Sbjct: 938 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997
Query: 1557 ATEDAKLRLEVNMQALKGQFERDLQARDEQNE---EKRRQLQRQLHEYETELEDERKQRA 1613
T++ K E + Q L DLQA +++ + + +L++Q+ + E LE E+K R
Sbjct: 998 LTKEKKALQEAHQQTLD-----DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRM 1052
Query: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
AK+KLEGDLK + +++ ++L+K + ++ + Q ++ED +A ++
Sbjct: 1053 DLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQK 1112
Query: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1733
KE + + + LE ++ + A AE+ R E EE++E L + +A + ++
Sbjct: 1113 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKK 1172
Query: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKA-TQQAEQLSNELATERSTAQKNESARQQLER 1792
EA ++ +LEE EA + +RK +L ++ + QK E + +++
Sbjct: 1173 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM 1232
Query: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
+ +L S + + A K + LE ++++L+ + E++ R T + +
Sbjct: 1233 EIDDLASNVETVSKA-KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291
Query: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATE 1912
E Q++++ + Q + ++++LKRQLEE + + + + + D E
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLRE 1351
Query: 1913 SNEAMGREVNALKSKLRRGN 1932
E L+ L + N
Sbjct: 1352 QYEEEQESKAELQRALSKAN 1371
Score = 96.3 bits (238), Expect = 3e-19
Identities = 78/366 (21%), Positives = 165/366 (45%), Gaps = 44/366 (12%)
Query: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADSAIKGREE 1642
K + ++++ + E + + + A + A +K+LE + DL+LQ + +G +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 1643 A-------IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
A IK +L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
+ K QQ + L L E+ E A+++LE K + + ++E
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE-------- 1078
Query: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
++Q++++ LK+K+ ++ + ++EDE+ + Q +++ ++
Sbjct: 1079 -----------KQQLDEK----------LKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1176
Query: 1936 FVPSRR 1941
F RR
Sbjct: 1177 FQKMRR 1182
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 1423 bits (3683), Expect = 0.0
Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%)
Query: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
AK V+V K+ F +I+ +G +V V+ E G +TV D + MNPPK+ K+EDMA
Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
Query: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
Query: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
Query: 209 -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
Query: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
KSR + Q + ER++HIFY + + K ++ LL+ +Y F+S G + + + D E
Sbjct: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
T A+ I+GF+ EE++SI K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 333 MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392
Query: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
+N D +++ PR+KVG + V K QT EQ AV ALAKA YE++F W++ R+N+ LD
Sbjct: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 512 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568
Query: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
PK +K K E F++IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 569 PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628
Query: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
G + K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 629 TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683
Query: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743
Query: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QA CRG+LA
Sbjct: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803
Query: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
R + + ++ A+ IQ N +++ +++W W +LF K+KPLL+ E+EM ++E Q
Sbjct: 804 RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863
Query: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
K K+ K+E + KELE+K L +EKN LQ Q+QAE E A+AEE +L K +LE
Sbjct: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923
Query: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 924 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983
Query: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 984 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043
Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
L++E+K R +LE+ KRKLEGD E I D++ + +L +L KKE E+ ++++DE
Sbjct: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103
Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163
Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223
Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
+K K ++ E DLA + + +AK +E + LE Q+ EL+SK + +R +L +
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283
Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
+LQ E + L+E E +L++ + + Q+++ + L+EE + K ++ L+
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343
Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
+ + L++Q +EE E+K L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403
Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
+ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LAE K
Sbjct: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463
Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
+ E + ++ EAR T+ + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523
Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583
Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
+DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643
Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
EA++ R Q +KD Q L+DA S++++ E++A L+A++ +L+ L ER
Sbjct: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703
Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ +K
Sbjct: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763
Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
A A ++ EL E+ T+ E ++ +E+ K+L+ +L E E K I LEA
Sbjct: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823
Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
++ +LE +VE E + A K L++ ++++KE+ Q E++RK + ++ +K A+VK
Sbjct: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883
Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
KRQ EEAEE+S A RKLQ EL+EA E + +VN L+ K R
Sbjct: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
Score = 235 bits (599), Expect = 4e-61
Identities = 225/1025 (21%), Positives = 456/1025 (44%), Gaps = 121/1025 (11%)
Query: 836 RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
+L K+K + + EEE+ A+ + +K ++ + + ++ +LE +++ +EK+ +
Sbjct: 920 QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 979
Query: 895 QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
+++ TE A +E +L +K+ L+E + L+ EED+ L + K+ QQ+ D
Sbjct: 980 KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039
Query: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
LE LE+E+ R L+ K E +K ++ I+ ++++ +L ++ K E IS+L +
Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099
Query: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
+ +E+ L K + ++ I ELE ++ E SR + EK + L + + E++ +
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159
Query: 1075 Q-AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSERA 1132
A A+++M K+E E Q L++ Q +R+ +++L E +D+ +
Sbjct: 1160 GGATSAQIEMN-KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218
Query: 1133 ARNKAEKQKRDLGEELEALKTE-----------------LEDTLDSTATQQELRAKREQE 1175
+ K EK+K ++ E++ L + LED L +++E + + +
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278
Query: 1176 VTVLKKALDEETRSHEAQVQEM----------RQKHAQAVEELTEQLEQFKRAKANL--- 1222
+T + L E+ Q+ E +Q Q +EEL QLE+ +AK L
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 1223 --------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKKK 1256
D ++ E+E A R L +A EV E KKK
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398
Query: 1257 L-------EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
L E V+ + +KC+ E+ + L ++V L +VE + K K
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458
Query: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
+A + ++T L+ ++ ++ T+L +++ DQL+ +NL++ IS L
Sbjct: 1459 LAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1518
Query: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
Q+++ K++ + + +E+ K Q +E E + +++ N+++ E+
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578
Query: 1430 DDLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL 1488
D + + D + QL N + L E + + + E + E E +
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638
Query: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
R EAL + K + ++D + S++D+ + + +E+ L+ ++EE++ L
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698
Query: 1549 EELE--------DELQATE-------------DAKLRLEVNMQALKGQFERDLQ-ARDEQ 1586
E+ E + L A+E + K +LE ++ ++G+ E LQ AR+ +
Sbjct: 1699 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAE 1758
Query: 1587 NEEKR----------------------RQLQRQLHEYETELE---DERKQRALAAAAKK- 1620
+ K+ ++++ + + +L+ DE +Q AL K+
Sbjct: 1759 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1818
Query: 1621 -KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
KLE +++LE + +S K EA+K LRK + ++K+ + E+ R + + + +
Sbjct: 1819 QKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1878
Query: 1680 KKAKSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
K KS +A+ + Q + A+ + Q +LE+ E ++A S N L+ + R + +
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTK 1936
Query: 1738 IAQLE 1742
+ E
Sbjct: 1937 VISEE 1941
Score = 182 bits (462), Expect = 3e-45
Identities = 185/809 (22%), Positives = 371/809 (45%), Gaps = 92/809 (11%)
Query: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
+ EK+ + EE + +K EL S A ++EL E+ VT+LK+ D +Q
Sbjct: 850 ETEKEMATMKEEFQKIKDELAK---SEAKRKELE---EKMVTLLKEKND---------LQ 894
Query: 1196 EMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEKENADLAGELRVLGQAKQEVEHKK 1254
Q A+ + + E+ +Q + K L+ K K+ E+ + + E+ KK
Sbjct: 895 LQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDE--------EEINAELTAKK 946
Query: 1255 KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
+KLE + EL+ D E A++ + H +N+V+++T + + KL K+ +L
Sbjct: 947 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQ 1006
Query: 1315 SQLQDTQELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Q T + LQ E K+N TK + +LE++ + L+ L++E + + +LER L L
Sbjct: 1007 EAHQQTLDDLQAE-EDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL 1065
Query: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
+++ + D + + L+E K+ + EI NL + E++ A +L+K LQ +++L
Sbjct: 1066 KLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELE 1125
Query: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
+++ +R + EK++ + L E IS + + A+ + + +
Sbjct: 1126 EEIEAERASRAKAEKQRSDLSRELEE---ISERLEEAGGATSAQIEMNKKREAEFQKMRR 1182
Query: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
+ EA + E T L+ + D V+ ++G+ + L++ K+ LE + EMK ++++L
Sbjct: 1183 DLEEATLQHEATAATLRKKHADSVA---ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1239
Query: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE-------KRRQLQRQLHEYETELE 1606
++ AK LE + L+ Q +L++++E+ + +R +LQ + E+ +L+
Sbjct: 1240 NVETVSKAKGNLEKMCRTLEDQLS-ELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298
Query: 1607 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1666
++ + + K+ +++L+ Q + IK + L+ + + + E+ +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358
Query: 1667 SRDEIF-ATAKENEKKAK---SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLS 1722
S+ E+ A +K N + A+ E D +Q E+L A++ Q + + AEE +++
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQ----RLQAAEEHVEAVN 1414
Query: 1723 GRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1781
+ A L+ K+RL+ + L ++E A+ + R + + Q
Sbjct: 1415 AKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK----------Q 1464
Query: 1782 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAAT 1841
K E +LE KE RS G K K+ A E + QLE
Sbjct: 1465 KCEETHAELEASQKEARSL-----GTELFKIKN---AYEESLDQLE-------------- 1502
Query: 1842 KSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1901
+LK+++K L++ ++ D EQ +G R+ +L++ ++ E+E + A
Sbjct: 1503 -TLKRENKNLQQ---EISD-------LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALE 1551
Query: 1902 KLQRELDEATESNEAMGREVNALKSKLRR 1930
+ + L+ + E+N +KS++ R
Sbjct: 1552 EAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Score = 141 bits (356), Expect = 6e-33
Identities = 123/560 (21%), Positives = 255/560 (45%), Gaps = 36/560 (6%)
Query: 1378 KKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLD 1437
K L A T + + K+ FQK + + + A +LE+ L +E +DL + +
Sbjct: 843 KPLLKSAETEKEMATMKEEFQK----IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ 898
Query: 1438 NQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALE 1497
+ + +++ E++ DQL+ + + +K + +RAE E E
Sbjct: 899 AEAEGLADAEER---CDQLIKTKIQLEAKIKEVTERAEDEE------------------E 937
Query: 1498 AKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL-Q 1556
EL + L+ E +L DD+ + ++EK K A E +++ + ++ L++ + +
Sbjct: 938 INAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAK 997
Query: 1557 ATEDAKLRLEVNMQALKGQFERDLQARDEQNE---EKRRQLQRQLHEYETELEDERKQRA 1613
T++ K E + Q L DLQA +++ + + +L++Q+ + E LE E+K R
Sbjct: 998 LTKEKKALQEAHQQTLD-----DLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRM 1052
Query: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
AK+KLEGDLK + +++ ++L+K + ++ + Q ++ED +A ++
Sbjct: 1053 DLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQK 1112
Query: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1733
KE + + + LE ++ + A AE+ R E EE++E L + +A + ++
Sbjct: 1113 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKK 1172
Query: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKA-TQQAEQLSNELATERSTAQKNESARQQLER 1792
EA ++ +LEE EA + +RK +L ++ + QK E + +++
Sbjct: 1173 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM 1232
Query: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
+ +L S + + A K + LE ++++L+ + E++ R T + +
Sbjct: 1233 EIDDLASNVETVSKA-KGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESG 1291
Query: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATE 1912
E Q++++ + Q + ++++LKRQLEE + + + + + D E
Sbjct: 1292 EFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLRE 1351
Query: 1913 SNEAMGREVNALKSKLRRGN 1932
E L+ L + N
Sbjct: 1352 QYEEEQESKAELQRALSKAN 1371
Score = 96.3 bits (238), Expect = 3e-19
Identities = 78/366 (21%), Positives = 165/366 (45%), Gaps = 44/366 (12%)
Query: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQADSAIKGREE 1642
K + ++++ + E + + + A + A +K+LE + DL+LQ + +G +
Sbjct: 847 KSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLAD 906
Query: 1643 A-------IKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
A IK +L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
+ K QQ + L L E+ E A+++LE K + + ++E
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENE-------- 1078
Query: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
++Q++++ LK+K+ ++ + ++EDE+ + Q +++ ++
Sbjct: 1079 -----------KQQLDEK----------LKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1118 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1176
Query: 1936 FVPSRR 1941
F RR
Sbjct: 1177 FQKMRR 1182
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 1420 bits (3676), Expect = 0.0
Identities = 777/1908 (40%), Positives = 1186/1908 (62%), Gaps = 22/1908 (1%)
Query: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
AK V+V K+ F A+++ +G +V + E G VTV D + MNPPK+ K+EDMA
Sbjct: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92
Query: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V Y+GKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152
Query: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+ +
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTS 212
Query: 212 GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLE
Sbjct: 213 GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272
Query: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
KSR Q + ER++HIFY +++ K + LL+ +Y F+S G + +P+ D E
Sbjct: 273 KSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEEL 332
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
T A+ I+GF+ +E++SI K+ +V+ GN+ FK+++ +QA A K +L
Sbjct: 333 MATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQN 392
Query: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
+N D +++ PR+KVG + V K QT +Q AV ALAKA Y+++F W++TR+N+ LD
Sbjct: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLD- 451
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 512 TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568
Query: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
PK K K E FS+IHYAG VDYN + WL KN DPLN+ V L S+ K +A L+
Sbjct: 569 PKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF---- 624
Query: 624 RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
VG A+ K K F+TV L++E L KLMT LR+T P+FVRCIIPN
Sbjct: 625 --VGATG-AEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681
Query: 684 EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
K G ++ LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 682 TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741
Query: 743 GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
K+A ++ ++++D Y+ G +K+FF+ G+L LEE RD K+ +I QAMCRG+LA
Sbjct: 742 SKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLA 801
Query: 803 RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
R + K ++ ++ IQ N A++ +++W W +L+ K+KPLL+ E+EM ++E +
Sbjct: 802 RVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861
Query: 863 KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
KTKE K E + KELE+K L +EKN LQ Q+QAE + A+AEE +L K +LE
Sbjct: 862 KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEA 921
Query: 923 ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
+ E+ R E+EE+ +L A+++K+ + +L++ +++ E K++ EK E K+K
Sbjct: 922 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
Query: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
L +E+ +D+ KL+KE+K L+E +L EE+K LTK K K E + +LE
Sbjct: 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1041
Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
L++E+K R +LE+ KRKLEGD E D++ +L +L KKE E+ ++++DE
Sbjct: 1042 LEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE 1101
Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
A KKI+EL+ I +L+E++++ERA+R KAEKQ+ DL ELE + LE+ +T
Sbjct: 1102 QALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161
Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
+ Q E+ KRE E +++ L+E T HEA +R+KHA +V EL EQ++ +R K L
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221
Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
+K K ++ E DLA + + +AK +E + LE Q+ E+++K + +R +L +
Sbjct: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQR 1281
Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
+LQ E + L+E + +L++ + + Q+++ + L+EE + K ++ L+
Sbjct: 1282 ARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSR 1341
Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ + +
Sbjct: 1342 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401
Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
++ + E A LEKTK RLQ E++DL++D++ + L+KKQR FD++LAE K
Sbjct: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461
Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
+ E + ++ E+R T+ + A EE+L+ E L+R NK L+ E+ DL
Sbjct: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521
Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
+ GK +HELEK K+ +E + E++ LEE E L+ E LR+++ + +K + +R +
Sbjct: 1522 EGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1581
Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
+DE+ ++ +R R + ++ L+ E + R A KKK+EGDL ++E+Q + A +
Sbjct: 1582 EKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641
Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
EA++ R QA +KD Q L+DA S++++ E++A L+A++ +L+ L ER
Sbjct: 1642 EALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701
Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
+RK A+ E + +E + + +L + K++LE I+Q++ E+E+ ++ +K
Sbjct: 1702 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKK 1761
Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
A A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LEA
Sbjct: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1821
Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
++ +LE +VE E + A K L++ ++K+KE+ Q E++RK + ++ +K A+VK
Sbjct: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
KRQ EEAEE+S + R++Q EL+EA E + +VN L+ K R
Sbjct: 1882 YKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
Score = 179 bits (454), Expect = 2e-44
Identities = 181/808 (22%), Positives = 368/808 (45%), Gaps = 90/808 (11%)
Query: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ 1195
+ EK+ ++ EE E K EL T A ++EL E+ VT++++ D +Q
Sbjct: 848 ETEKEMANMKEEFEKTKEELAKT---EAKRKELE---EKMVTLMQEKND---------LQ 892
Query: 1196 EMRQKHAQAVEELTEQLEQFKRAKANLD-KNKQTLEKENADLAGELRVLGQAKQEVEHKK 1254
Q A ++ + E+ +Q + K L+ K K+ E+ + + E+ KK
Sbjct: 893 LQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDE--------EEINAELTAKK 944
Query: 1255 KKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
+KLE + EL+ D E A++ + H +N+V+++T + + KL K+ +L
Sbjct: 945 RKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQ 1004
Query: 1315 SQLQDTQELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
Q T + LQ E K+N TK + +LE++ + L+ L++E + + +LER L L
Sbjct: 1005 EAHQQTLDDLQAE-EDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL 1063
Query: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
+++ D + + L+E K+ + E+ L + E++ A +L+K LQ +++L
Sbjct: 1064 KLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE 1123
Query: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
+++ +R + EK++ + L E IS + + A+ + + +
Sbjct: 1124 EEIEAERASRAKAEKQRSDLSRELEE---ISERLEEAGGATSAQIEMNKKREAEFQKMRR 1180
Query: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
+ EA + E T L+ + D V+ ++G+ + L++ K+ LE + EMK ++++L
Sbjct: 1181 DLEEATLQHEATAATLRKKHADSVA---ELGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1237
Query: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE-------KRRQLQRQLHEYETELE 1606
++ AK LE +AL+ Q +++ ++E+ + +R +LQ + EY +L+
Sbjct: 1238 NMETVSKAKGNLEKMCRALEDQLS-EIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296
Query: 1607 DERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARA 1666
++ + + K+ +++L+ Q + IK + L+ + + + E+ +
Sbjct: 1297 EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE 1356
Query: 1667 SRDEIF-ATAKENEKKAK---SLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLS 1722
++ E+ A +K N + A+ E D +Q E+L A++ Q + EE E + + +
Sbjct: 1357 AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCA 1416
Query: 1723 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782
+L+ K+RL+ + L ++E A+ + R + + QK
Sbjct: 1417 ---SLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK----------QK 1463
Query: 1783 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1842
E +LE KE RS E+ K K+ A E + QLE
Sbjct: 1464 CEETHAELEASQKESRSLSTEL-----FKIKN---AYEESLDQLE--------------- 1500
Query: 1843 SLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK 1902
+LK+++K L++ ++ D EQ +G R+ +L++ ++ E+E + A +
Sbjct: 1501 TLKRENKNLQQ---EISD-------LTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEE 1550
Query: 1903 LQRELDEATESNEAMGREVNALKSKLRR 1930
+ L+ + E+N +KS++ R
Sbjct: 1551 AEASLEHEEGKILRIQLELNQVKSEVDR 1578
Score = 98.2 bits (243), Expect = 7e-20
Identities = 86/366 (23%), Positives = 166/366 (45%), Gaps = 44/366 (12%)
Query: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL-------KDLELQ----ADSAIK 1638
K + ++++ + E E +++ A A +K+LE + DL+LQ ADS
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
Query: 1639 GRE---EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
E + IK +L+A++K+ ED E+ A ++ E + L+ D+ L+
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 1696 LAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
LA E+ + + + + L EE+A L EK+ L+ Q ++L+ E+ + +
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST 1815
+ K QQ + L L E+ R LER ++L EG +K +ST
Sbjct: 1025 TKAKIKLEQQVDDLEGSLEQEKKI-------RMDLERAKRKL-------EGDLKLAQEST 1070
Query: 1816 IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875
+ I ++Q++++ ++K+ L+ K +EDE+ + Q +++ ++
Sbjct: 1071 M-----DIENDKQQLDEKLKKKEFEMSGLQSK----------IEDEQALGMQLQKKIKEL 1115
Query: 1876 NARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETS 1935
AR+++L+ ++E + R L REL+E +E E G +A + ++ + E
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-QIEMNKKREAE 1174
Query: 1936 FVPSRR 1941
F RR
Sbjct: 1175 FQKMRR 1180
Score = 72.8 bits (177), Expect = 3e-12
Identities = 57/278 (20%), Positives = 122/278 (43%), Gaps = 12/278 (4%)
Query: 851 EEEMQAKED---ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
++ ++++ED +L + R + E++EL Q + + +++L +E
Sbjct: 1662 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLH 1721
Query: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
L K++LE + +++ +E+ + + + KK + E+L++E+
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 968 KLQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKA 1022
L+ K E +K L+ + D+ +L+ K+ + LE R+ +L + E+++
Sbjct: 1782 HLERMKKNLEQTVKDLQHRL----DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1837
Query: 1023 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
K KHE + EL + +++ K+ L+ L KL+ + Q + + Q
Sbjct: 1838 VEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNL 1897
Query: 1083 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
+ + + EL+ A R D +Q N K RE+ I
Sbjct: 1898 SKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935
Score = 72.0 bits (175), Expect = 5e-12
Identities = 68/292 (23%), Positives = 125/292 (42%), Gaps = 22/292 (7%)
Query: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
L+ T+ A ++L+++ + + NLLQ AE EE+R L ++
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQ----------AEIEELRATL----EQT 1699
Query: 921 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
E E L + +R Q L + + LE + + + + + E AE K
Sbjct: 1700 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKA 1759
Query: 981 KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1032
KK + +E+ D + L + +K LE+ + DL L E E+ A K K K
Sbjct: 1760 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1819
Query: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
E+ + ELE ++ E+K E K RK E + Q + + I L+ + K + ++
Sbjct: 1820 EARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKV 1879
Query: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1144
++ + ++ Q N L K R ++ + + +E D + NK + R++
Sbjct: 1880 KSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREV 1931
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 1387 bits (3591), Expect = 0.0
Identities = 779/1916 (40%), Positives = 1160/1916 (60%), Gaps = 28/1916 (1%)
Query: 30 WAAKRLVWVPSEKQGFEAASIKEEK-GDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVE 88
W K+ VWVP E+ + A +K E G V VE ++ K + V + ++Q MNPP+F +E
Sbjct: 71 WDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVE-TKDQKVLMVREAELQPMNPPRFDLLE 129
Query: 89 DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148
DMA +T LNEASVLHNLR+RY +IYTYSGLFCV +NPYK LP+Y+ +V YKGK+R
Sbjct: 130 DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRS 189
Query: 149 EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS--SHKGKK 206
+ PPHIYA+AD AY ML++R++QS+L TGESGAGKT NTK+VIQY A+VA+ GKK
Sbjct: 190 DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 249
Query: 207 D----TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
T G LE Q+++ANP +EAFGNAKT++NDNSSRFGKFIRI+F +G + A+I+
Sbjct: 250 AQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADID 309
Query: 263 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAA 320
+YLLEKSR I Q ER++H++Y +++G K +++ D+LL N +Y F S G + +
Sbjct: 310 SYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQ-DMLLLSMNPYDYHFCSQGVITVDNM 368
Query: 321 QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 380
D E T AM I+GFS +E+ + K+V ++L GN+ FK+++ +QA +A K
Sbjct: 369 NDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADK 428
Query: 381 VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 440
+LMG++ D + +L PR++VG + V K Q+ EQ FAV ALAKATY+RLFRW+++R+
Sbjct: 429 AAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRI 488
Query: 441 NKALD-KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
N+ LD K RQ F+G+LDIAGFEIFE NSFEQLCIN+TNEKLQQ FN MF+LEQEEY
Sbjct: 489 NQTLDTKLPRQ--FFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEY 546
Query: 500 QREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-G 558
+REGI+W FIDFGLDLQPCI+LIE+P G+L++L+EEC FPKA+D SF KL G
Sbjct: 547 KREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDNHAG 603
Query: 559 SHPKFQKP---KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFV 615
P FQ+P K+ K + F ++HYAG V Y+ WL KN DPLN+ V + S ++ +
Sbjct: 604 KSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLL 663
Query: 616 ADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNF 675
A L+++ + S + K F+TV QL+KE L KLMT LR T P+F
Sbjct: 664 ATLYENY-----AGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHF 718
Query: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
VRCI+PN K G +DAFLVL QLRCNGVLEGIRICRQGFPNR+++ +FRQRY IL +A
Sbjct: 719 VRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSA 778
Query: 736 IPKG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQ 794
IP FMD ++A ++ +L+LD Y+ G +K+FF+ G+L LEE RD ++ V+ Q
Sbjct: 779 IPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQ 838
Query: 795 AMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEM 854
A RG L R + + A+ IQ N A+ ++NW W +LF K+KPLL+ + EEE+
Sbjct: 839 ARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEEL 898
Query: 855 QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 914
A EL+ + AE + +ELE+ H +T+EKN L QLQAE + A+AEE L
Sbjct: 899 AALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLI 958
Query: 915 AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 974
K +LE + E+ RLE+EE+ L A R+K+ + +L++ +++ + K + EK
Sbjct: 959 KSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQ 1018
Query: 975 TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034
E K+K L +E+ +D+ +L+KE+K L+E +L EE++ LTK K + E
Sbjct: 1019 ATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQ 1078
Query: 1035 MISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094
+ +LE L++E+K R + E+ KRKLEGD E +AD +L+ +L KK+ EL
Sbjct: 1079 QVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQ 1138
Query: 1095 ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154
R++DE KKI+EL+ +L+E+L++ERAAR + EKQ+ + ELE L
Sbjct: 1139 LSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSER 1198
Query: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214
LE+ ++A Q+E KRE E+ L++ L+E HEA V +R+K A+ EL EQ++
Sbjct: 1199 LEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDS 1258
Query: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
+R + L+K K L E DLA + L +AK E + E Q+ E + K + +R
Sbjct: 1259 LQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ 1318
Query: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1334
A+ + + +LQ E ++ +L E E +L++ A + L++ + L+EE++ K +
Sbjct: 1319 LADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSAL 1378
Query: 1335 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEG 1393
+ ++ L + + L++Q +EE EA+ L+R +S N +++ + K + D E LEE
Sbjct: 1379 AHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEA 1438
Query: 1394 KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
KK+ ++ + E A LEK K RLQ E +D+ ++L+ + L+KKQR
Sbjct: 1439 KKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHL 1498
Query: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
++ L E + + E + A+ E+R T+ L EEALEA E L+R NK L+ E+
Sbjct: 1499 ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEI 1558
Query: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1573
DL GK++ ELEK+K+ALE + E++ LEE E L+ E LR+++ + +K
Sbjct: 1559 SDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1618
Query: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1633
+ +R L +DE+ RR QR + + L+ E + R A KKK+EGDL DLELQ
Sbjct: 1619 AEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQL 1678
Query: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693
A + EA R +QAQ+K+ Q ++ + E+ A+ E++A L A+L +L+
Sbjct: 1679 GHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELR 1738
Query: 1694 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1753
L ER+R+ A+ E E E L S L ++K++LEA +AQL E+EE
Sbjct: 1739 AALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERR 1798
Query: 1754 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1813
++ +KA A ++ EL E+ T+ E ++ LE+ +EL+++L E E A K
Sbjct: 1799 EAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGK 1858
Query: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1873
+ LEAK+ +LE +++ E ++ A K +++ ++++KE+ Q E++RK + ++ +
Sbjct: 1859 KQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVD 1918
Query: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
K ++VK KRQ EEAE+++ A RK Q ELD+A E + + N L+++ R
Sbjct: 1919 KLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTR 1974
Score = 152 bits (384), Expect = 3e-36
Identities = 160/692 (23%), Positives = 308/692 (44%), Gaps = 79/692 (11%)
Query: 1276 AELNDKVHKLQNEVESVTGMLNEAEGKA-------IKLAKDVASLSSQLQDTQELLQE-E 1327
A+ +++ L+ E+ + G L AE K + + ++ L+ QLQ Q+ L + E
Sbjct: 892 AQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAE 951
Query: 1328 TRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTV 1387
R L + +K+ QLE + L ++L++E E +L L + ++ KK + D T+
Sbjct: 952 ERCHLLIKSKV-QLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTL 1010
Query: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
E+ K+ + +++NLT++ + +L K K LQ+ + DL + VS L
Sbjct: 1011 AKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALT 1070
Query: 1448 KKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNK 1507
K + + +Q + + + + R E R+ E ++ +A + K++LE K
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130
Query: 1508 MLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEV 1567
+E+ L +D +++K +++E++ + EELE+EL+A A+ R+E
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQK-------KIKELQARAEELEEELEAERAARARVEK 1183
Query: 1568 NMQALKGQFERDLQARDEQNEEKR----------RQLQRQLHEYETELEDE--RKQRALA 1615
+ + R+L+ E+ EE R+ + +L ELE+ R + +A
Sbjct: 1184 Q----RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVA 1239
Query: 1616 AAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATA 1675
A +K+ EG +L Q DS + R+ KL+ + + + E++D A+ + +
Sbjct: 1240 ALRRKQAEG-AAELGEQVDSLQRVRQ-------KLEKEKSELRMEVDDLAANVETLTRAK 1291
Query: 1676 KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE 1735
EK ++ E L +A ++ EEL +LA + + R LQ E
Sbjct: 1292 ASAEKLCRTYEDQL--------------SEAKIKVEELQRQLADASTQRGRLQTES---- 1333
Query: 1736 ARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNK 1795
+L LEE++ + +S A Q E+L +L E A Q L R +
Sbjct: 1334 ---GELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQAL-RHDC 1389
Query: 1796 ELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEIL 1855
+L + HE E +++ + ++ A++AQ + E +A ++ T+ L++ KKL L
Sbjct: 1390 DLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQR---TEELEEAKKKLALRL 1446
Query: 1856 LQVEDERKMAEQYKEQAEKGNARVK--------QLKRQ------LEEAEEESQRINANRR 1901
+ E+ + A EK R++ +L+R L++ + +R RR
Sbjct: 1447 QEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERR 1506
Query: 1902 KLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
+ + E+ E+ + R + +LR G+E
Sbjct: 1507 RQEEEMQRELEAAQRESRGLGTELFRLRHGHE 1538
Score = 87.8 bits (216), Expect = 9e-17
Identities = 94/382 (24%), Positives = 166/382 (43%), Gaps = 24/382 (6%)
Query: 778 LEEERDLKITDVIMAFQAMCRGYLARK----AFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 833
LEE + L+I + +A LA K A +R Q A++ +Q + A + RN +
Sbjct: 1602 LEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQ-RAVESLQASLDAETRARN-E 1659
Query: 834 WWRLFTKVK--------PLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885
RL K++ L TRQ E QA +Q + +Q +E + L ++L
Sbjct: 1660 ALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLA---AEL 1716
Query: 886 TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE---LEEILHEMEARLEEEEDRGQQLQ 942
E+ L+ + L AE EE+R L ++ E+ L E RL + L
Sbjct: 1717 HEQAQALERRASL---LAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLL 1773
Query: 943 AERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERK 1002
++KK+ + L ++EE R++ + + A + +E+ D + L + +K
Sbjct: 1774 NQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK 1833
Query: 1003 LLEERISDLTTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLE 1061
LE+ + +L L E E+ A + K K E+ + ELE L E+K E K RK E
Sbjct: 1834 TLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHE 1893
Query: 1062 GDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHIS 1121
+ Q + + +A ++ + K + ++++ + ++ Q N L K R+ + +
Sbjct: 1894 RRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELD 1953
Query: 1122 DLQEDLDSERAARNKAEKQKRD 1143
D +E D NK + RD
Sbjct: 1954 DAEERADMAETQANKLRARTRD 1975
Score = 81.6 bits (200), Expect = 7e-15
Identities = 63/276 (22%), Positives = 119/276 (43%), Gaps = 3/276 (1%)
Query: 846 QVTRQEEEMQAKE--DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Q R EE+ A E ++ Q + R EL+EL Q + L +++L TE
Sbjct: 1703 QAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERL 1762
Query: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
L +K++LE L ++ +EE ++ + + KK + E+L++E+
Sbjct: 1763 NLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQ 1822
Query: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKA 1022
L+ K T E +++L+ + + + K++ + LE ++ +L L E++K
Sbjct: 1823 DTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKH 1882
Query: 1023 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
K KHE + EL + +++ K+ ++ L KL+ + Q + + Q
Sbjct: 1883 AEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNL 1942
Query: 1083 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
+ K + EL A R D Q N + R+ G
Sbjct: 1943 AKYRKAQHELDDAEERADMAETQANKLRARTRDALG 1978
Score = 68.9 bits (167), Expect = 5e-11
Identities = 70/318 (22%), Positives = 150/318 (47%), Gaps = 21/318 (6%)
Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE- 1700
+A ++L L+A+++ + L A A R E+ T ++ L L Q++LA AE
Sbjct: 893 QAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEE 952
Query: 1701 ------RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA 1754
+++ Q + + +EL+E L L +R+LE +L++++++ + + A
Sbjct: 953 RCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTL-A 1011
Query: 1755 MSDRVRKATQ-QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1813
+++ ++AT+ + + L+ E+A + + ++ L+ +++ L E V + K
Sbjct: 1012 KAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTK 1071
Query: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1873
+ + LE ++ LE +EQE + + ++ ++ + LK V D A Q K+Q E
Sbjct: 1072 AKLR-LEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD----AAQDKQQLE 1126
Query: 1874 ----KGNARVKQLKRQLEEAEEESQRINANRRKLQ---RELDEATESNEAMGREVNALKS 1926
K ++ + QL ++E+ + ++ ++LQ EL+E E+ A V ++
Sbjct: 1127 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRA 1186
Query: 1927 KLRRGNETSFVPSRRSGG 1944
+ R E +GG
Sbjct: 1187 EAARELEELSERLEEAGG 1204
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 1387 bits (3590), Expect = 0.0
Identities = 760/1909 (39%), Positives = 1164/1909 (60%), Gaps = 24/1909 (1%)
Query: 32 AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
+K+ +V K+ + I+ + D+V+V+ +++ + +T+ D + MNPPKF K+EDMA
Sbjct: 34 SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92
Query: 92 ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
+T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y ++V Y+GKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152
Query: 152 PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209
PHI++I+D AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A + KK+T
Sbjct: 153 PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPG 212
Query: 210 -ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268
+ G LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F TG + A+IETYLLEK
Sbjct: 213 KMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 272
Query: 269 SRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMF 326
SR Q ER++HIFY +++ K ++ DLLL N ++ F+S G V + + D E
Sbjct: 273 SRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDDSEEL 331
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
T A+ I+GFS EE++ I K+ +V+ GN+ FK+++ +QA A K +LMG
Sbjct: 332 LATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMG 391
Query: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
+N + + + PR+KVG + V K Q +Q +V ALAKA YE++F W++TR+N+ LD
Sbjct: 392 LNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD- 450
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
T + F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 451 TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
FIDFG+DL CIELIE+P G+ ++L+EEC FPKATD SF KL + G FQK
Sbjct: 511 EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 567
Query: 566 PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
PK K K E FS++HYAG VDYN + WL KN DPLN+ V L SS K ++ L+ +
Sbjct: 568 PKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYA 627
Query: 624 RIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPN 682
A+ +S KKG F+TV +++E L KLMT LR+T P+FVRC+IPN
Sbjct: 628 G-------AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPN 680
Query: 683 HEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FM 741
K G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL A+AIP+G F+
Sbjct: 681 ETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFI 740
Query: 742 DGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL 801
D K A ++ ++++D +R G +K+FF+ G+L LEE RD K+ ++ + QA+CRGYL
Sbjct: 741 DSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYL 800
Query: 802 ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 861
R F K ++ ++ IQ N +++ +++W W LF K+KPLL+ E+EM +++
Sbjct: 801 MRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDF 860
Query: 862 QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921
++TKE ++E KELE+K L +EKN LQ Q+Q+ETE +AEE L K LE
Sbjct: 861 ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLE 920
Query: 922 EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 981
+ E+ RLEEEE+ +L A+++ + + L+ +++ E K++ EK E K+K
Sbjct: 921 AKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVK 980
Query: 982 KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1041
L +E+ +++ +KL+KE+K L+E +L EE+K L K+ K E +LE
Sbjct: 981 NLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEG 1040
Query: 1042 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1101
L++E+K R +LE+ KRKLEGD E I DL+ +++ +L KKE EL A++DD
Sbjct: 1041 SLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD 1100
Query: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1161
E KKI+EL+ I +L+E++++E R K EKQ+ DL ELE + LE+ +
Sbjct: 1101 EQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGA 1160
Query: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
T+ Q E+ KRE E +++ L+E T HEA +R+K A +V EL EQ++ +R K
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220
Query: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
L+K K L+ E D+A + L ++K +E + +E Q E+++K + +LN +
Sbjct: 1221 LEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280
Query: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
+LQ + ++ + E E +L K +L+ QL++ + ++EET+ K ++ L+
Sbjct: 1281 KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSS 1340
Query: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKE 1400
+ + L++Q +EE EAK L+R +S N +++ + K + D E LEE KK+ +
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Query: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
++ + E + LEKTK RLQ E++DL+ DL+ + L+KKQR FD++LAE
Sbjct: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460
Query: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
K + E + A+ E+R T+ + A EE ++ E L R NK L+ E+ DL
Sbjct: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520
Query: 1521 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDL 1580
+ GKN+ E EK+K+ +E + +++ LEE+E L+ E LR+++ + +K + +R +
Sbjct: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKV 1580
Query: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640
+DE+ E+ +R QR ++ L+ E + R A KKK+EGDL ++E+Q + +
Sbjct: 1581 IEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQM 1640
Query: 1641 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 1700
E K LR +Q Q+KD Q L+DA S +++ E++ L +L +++ L E
Sbjct: 1641 AETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTE 1700
Query: 1701 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
R R+ ++ E + ++ + S +L + K++LEA IAQ + E+E ++ +
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760
Query: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
KA A ++ EL E+ T+ E ++ LE+ K+L+ +L E E K I LE
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820
Query: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
++ +LE +++ E + A K + ++K+KE+ Q E++ K + ++ +K A+VK
Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880
Query: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
KRQ EEAEE++ + R++Q EL+EA E + +VN L++K R
Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSR 1929
Score = 219 bits (559), Expect = 2e-56
Identities = 221/911 (24%), Positives = 418/911 (45%), Gaps = 120/911 (13%)
Query: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
EE+++ KE EL + + + + + ++K +L L+E+++AE L A+ E+ R
Sbjct: 1081 EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQR 1140
Query: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAE----------------------RKKM 948
LA + +E+ E L E + + ++ +AE RKK
Sbjct: 1141 SDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQ 1200
Query: 949 AQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERI 1008
A + +L EQ++ + +QKL+ EK + +I + I + + + + + +E++
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQF 1260
Query: 1009 SDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE-------KSRQ----ELEKLK 1057
S++ ++ + +L K + ++ EL R++++E KS+Q +LE+LK
Sbjct: 1261 SEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320
Query: 1058 RKLEGDASDFHEQIADLQAQIAE---LKMQLAKKEE---ELQAALARLDDEIAQ-----K 1106
R++E + + LQ+ + L+ Q +++E ELQ AL++ + E+AQ +
Sbjct: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380
Query: 1107 NNALKKIRELEG-------HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1159
+A+++ ELE + + +E+ ++ + EK K+ L E+E L +LE +
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440
Query: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ------KHAQAVEELTEQLE 1213
+ AT + + ++ + K+ LDE EA +E R K A EE+ +QLE
Sbjct: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLE 1500
Query: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1273
+R NL ++E +DL ++ G+ QE E KK +E + +LQ + E
Sbjct: 1501 TLRRENKNL-------QEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEG 1553
Query: 1274 ARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQE----ETR 1329
+ K+ ++Q E+ V +E + K I+ +++ L Q E LQ E R
Sbjct: 1554 SLEHEESKILRVQLELSQVK---SELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIR 1610
Query: 1330 QKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA 1389
+ + +++E + N ++ QL ++H+ T+ QL DS+ L D + E
Sbjct: 1611 SRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNED 1670
Query: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL---DDLVVDLDNQRQLVSNL 1446
L+E ++ L ++ EE A ++ E+T+ +QEL D V L +Q + N
Sbjct: 1671 LKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINT 1730
Query: 1447 EKK-QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
+KK + Q AE +N E AE +A++ T A +A L++ + LER
Sbjct: 1731 KKKLEADIAQCQAEVENS----IQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 1786
Query: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL 1565
K L+ ++DL D+ + L+ K+ Q+++++ ++ ELE+EL +
Sbjct: 1787 KKNLEQTVKDLQHRLDEAEQLA--LKGGKK----QIQKLENRVRELENELDVEQKR---- 1836
Query: 1566 EVNMQALKG--QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLE 1623
+ALKG ++ER ++ Q EE + + R L+D KL+
Sbjct: 1837 --GAEALKGAHKYERKVKEMTYQAEEDHKNILR--------LQD----------LVDKLQ 1876
Query: 1624 GDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAK 1683
+K + QA EEA +Q ++ + Q ELE+A D A ++ N+ +AK
Sbjct: 1877 AKVKSYKRQA-------EEAEEQANTQLSRCRRVQHELEEAAERAD--IAESQVNKLRAK 1927
Query: 1684 SLEADLMQLQE 1694
S + +++E
Sbjct: 1928 SRDVGSQKMEE 1938
Score = 160 bits (405), Expect = 1e-38
Identities = 160/745 (21%), Positives = 329/745 (44%), Gaps = 78/745 (10%)
Query: 1267 KCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQ-DTQELLQ 1325
K ++ E+ A + + + + E+ E E K + L ++ L Q+Q +T+ L+
Sbjct: 845 KSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMD 904
Query: 1326 EETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS 1385
E R + + +K+ LE + L ++L+EE E L L + S K+ + D
Sbjct: 905 AEERCEGLIKSKIL-LEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLEL 963
Query: 1386 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQ----QELDDLVVDLDNQRQ 1441
T+ +E+ K + +++NL+++ KL K K LQ Q LDDL V+ D
Sbjct: 964 TLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNG 1023
Query: 1442 LVSNLEKKQRKFDQL---LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
L+ K +++ D L L +EK + + + + E + + + + L
Sbjct: 1024 LIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEND------- 1076
Query: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
K+++E K + E+ L + DD + VH L+ K+ ++E++ ++EELE+E++A
Sbjct: 1077 KQQIEEKLKKKEFELSQLQAKIDD--EQVHSLQFQKK-----IKELQARIEELEEEIEAE 1129
Query: 1559 EDAKLRLEVNMQALKGQFERDLQ----------ARDEQNEEKRRQLQRQLHEYETELEDE 1608
+ ++E L + E + A+ E N+++ + Q+ + E E
Sbjct: 1130 HTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE---EAT 1186
Query: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
+ A AA +KK + +L Q D+ + +++ K+ +L+ ++ D +E S+
Sbjct: 1187 LQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSK 1246
Query: 1669 DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ 1728
I T + E + ++A Q + + + + + EL+ + S + L
Sbjct: 1247 SNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLT 1306
Query: 1729 DEKRRLEARIAQLEEELEEEQGNMEAMS----------DRVRKATQQAEQLSNELATERS 1778
K+ L ++ +L+ ++EEE AM+ D +R+ ++ ++ EL +R+
Sbjct: 1307 KSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAEL--QRA 1364
Query: 1779 TAQKNESARQ--------------QLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
++ N Q +LE K+L +L E E ++ S A+LE
Sbjct: 1365 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA-NSKCASLEKTKQ 1423
Query: 1825 QLEEQVEQEAREKQ-----AATKSLKQK--DKKLKEILLQVEDERKMAEQYKEQAEKGNA 1877
+L+ +VE R+ + AT KQ+ DK L E ++++ + E ++++ +
Sbjct: 1424 RLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLST 1483
Query: 1878 RVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREV-NALKSKLRRGNETSF 1936
+ +++ EE ++ + + + LQ E+ + TE G+ + A K+K
Sbjct: 1484 ELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTK-------KL 1536
Query: 1937 VPSRRSGGRRVIENADGSEEETDTR 1961
V +S + +E +GS E +++
Sbjct: 1537 VEQEKSDLQVALEEVEGSLEHEESK 1561
Score = 124 bits (311), Expect = 9e-28
Identities = 116/542 (21%), Positives = 246/542 (45%), Gaps = 47/542 (8%)
Query: 844 LLQVTRQEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAET 900
L + E +K L+KTK+R Q + E+ +++LE+ H+ ++K +++ AE
Sbjct: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460
Query: 901 ELYAEAEEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ- 958
+ + + + A K+ + L L +M EE D+ + L+ E K + +++ DL EQ
Sbjct: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520
Query: 959 ------LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLT 1012
L+E E ++ ++ EK + ++++E + + + +K+ + + L + S+L
Sbjct: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSL---EHEESKILRVQLELSQVKSELD 1577
Query: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072
+ E++E+ + +LK + L+ L E +SR + +LK+K+EGD ++ Q+
Sbjct: 1578 RKVIEKDEE---IEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLG 1634
Query: 1073 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA 1132
Q+AE + L + +L+ + LDD + + +++ +E L E+L+ +
Sbjct: 1635 HSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKV 1694
Query: 1133 ARNKAEKQKR-------DLGEELEAL---------------------KTELEDTLDSTAT 1164
A + E+ +R D + ++ L + E+E+++ +
Sbjct: 1695 ALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRN 1754
Query: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224
+E K + ++ + L +E + A ++ M++ Q V++L +L++ ++ K
Sbjct: 1755 AEEKAKKAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
Query: 1225 NK-QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
+ Q LE +L EL V + E K E +V+E+ + + + L D V
Sbjct: 1814 KQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVD 1873
Query: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
KLQ +V+S EAE +A + +L++ E Q + K R +
Sbjct: 1874 KLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGS 1933
Query: 1344 ER 1345
++
Sbjct: 1934 QK 1935
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 1241 bits (3212), Expect = 0.0
Identities = 708/1907 (37%), Positives = 1109/1907 (58%), Gaps = 30/1907 (1%)
Query: 33 KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
K+ W+P + + A +K + D V+ +G+ +++ +D IQ+MNPP+F +EDMA
Sbjct: 51 KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
Query: 93 LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
LT LNEASVLH L+ RY +IYTYSGLFCV +NPYK LP+Y ++++ YKGK+R E PP
Sbjct: 111 LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
Query: 153 HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITG 212
HI+A+A+ A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+ + +K G
Sbjct: 171 HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---G 227
Query: 213 ELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAI 272
LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F G + +I+ YLLEKSR I
Sbjct: 228 ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
Query: 273 RQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETV 330
Q ER +HIFY +++G KE DLLL N ++ F S G V + + D E T
Sbjct: 288 FQQAGERNYHIFYQILSGQKEL--HDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATE 345
Query: 331 EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVT 390
+AM I+GF +E+ K+ +++ GN+ FK++ +Q A K LMGIN +
Sbjct: 346 QAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSS 405
Query: 391 DFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-KTHR 449
+ + ++ PRIKVG + V + QT EQ AV AL+K+ YER+F+W++ R+N+ALD K R
Sbjct: 406 ELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSR 465
Query: 450 QGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFI 509
Q F+GILDI GFEI E NS EQLCIN+TNEKLQQ FN MF+LEQEEY++E IEW I
Sbjct: 466 Q--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSI 523
Query: 510 DFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQ 568
FGLDLQ CI+LIE+P G+L++L+EEC FPKATD +F KL G QKPK
Sbjct: 524 GFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKP 580
Query: 569 LKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626
K K E F ++HYAG V YN S WL KN D LN+ V ++ SS++ +A L+++
Sbjct: 581 DKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY---- 636
Query: 627 GLDQMAKMTESSLPSASKTKK--GMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHE 684
T+S++P K +K F+TV L+KE L KLMT L++T P+FVRCI PN
Sbjct: 637 ------MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVN 690
Query: 685 KRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDG 743
K G LD +LVL+QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL PK F+
Sbjct: 691 KIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSS 750
Query: 744 KQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLAR 803
++A ++ +LE+D YR G +K+FF+ G L LE RD +++ V FQA +G L R
Sbjct: 751 RKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMR 810
Query: 804 KAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQK 863
F K ++ A+ +IQ N A++ ++NW W RLF K+KPL++ + EE+ ++E +
Sbjct: 811 IKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQ 870
Query: 864 TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 923
++ +K+E + +EL+ K LT+EKN L QLQAE E A EE L K +LE
Sbjct: 871 LQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEAR 930
Query: 924 LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983
+ E+ R+EEEE+ +L A +K+ + +L++++++ E K + EK T E K+K L
Sbjct: 931 VKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNL 990
Query: 984 EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043
+E+ +++ +KL++ K+++E +L EEEK +L+K K E + ELE L
Sbjct: 991 TEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGAL 1050
Query: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1103
++E K+R E+ KLEG+ E + +L++ L +L KKE EL +++++E
Sbjct: 1051 EQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEK 1110
Query: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTA 1163
K ++EL+ I DL+E L++ER R K E+++ DL ++L L LE+ S+
Sbjct: 1111 GLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSL 1170
Query: 1164 TQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223
Q E+ K+E + L + ++E T E ++++HA ++ EL Q+E ++ K L+
Sbjct: 1171 AQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLE 1230
Query: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
K+K L+ E DL + + +AK E E ++ E +K + +L +
Sbjct: 1231 KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKT 1290
Query: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
KL +E L E E +L+++ ++ + Q++D + L++ET+ + ++ L++ +
Sbjct: 1291 KLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQR 1350
Query: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIE 1402
+ + L++Q +EE E K L R +S +N ++ + K + + E LE+ KK ++
Sbjct: 1351 DCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQ 1410
Query: 1403 NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN 1462
+ A LE+ +++LQ EL D + DL R + L++KQ + + LA+ K
Sbjct: 1411 EAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470
Query: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1522
+ D ++ E + T+ L L EE++ +E L R NK L+ E+ +L + +
Sbjct: 1471 KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVRE 1530
Query: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1582
KN+ E+EK K+ +E + E++ LEE E L+ E L ++ + K + ER L
Sbjct: 1531 GTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSE 1590
Query: 1583 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642
+DE+ E RR+ Q + ++ L+ E K R KKK+E DL ++ELQ A + E
Sbjct: 1591 KDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSE 1650
Query: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
A K L +LQ Q+KD Q +L+D+ ++ E++ L+++L L+ ER
Sbjct: 1651 ATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERG 1710
Query: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
R+ ++ E E E + + +L +K++LEA +A++++E EE + ++ +KA
Sbjct: 1711 RRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKA 1770
Query: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
+A LS EL ++ T E R+ +E+ +L+ +L E E + I LE++
Sbjct: 1771 AIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESR 1830
Query: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
+ +LE ++E E R A + ++ ++ +KE+ Q E+++K + + Q +K +V+
Sbjct: 1831 VRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNY 1890
Query: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
K+Q+E AE ++ + + +K Q EL+E E E +VN LK K R
Sbjct: 1891 KQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
Score = 114 bits (285), Expect = 9e-25
Identities = 100/469 (21%), Positives = 207/469 (44%), Gaps = 6/469 (1%)
Query: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
++E+QA EL K K +++ + L +++ L EE + L Q++ T+ E E+++
Sbjct: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542
Query: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
+ +K E++ L E E LE E + Q E + + +LE +L E++ + +
Sbjct: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLE---LLEAKAELERKLSEKDEEIENFR 1599
Query: 971 LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
++ + I L+ + ++++ +K +EE ++++ L+ + TK
Sbjct: 1600 RKQ---QCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLG 1656
Query: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
+ + I +L+++L + +L++ E S ++ DL++ + + EE
Sbjct: 1657 QLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEE 1716
Query: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
EL A R++ Q + L + ++LE ++ +Q++ + AE++ + E
Sbjct: 1717 ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAAN 1776
Query: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
L EL+ D+ A + R EQ +T L+K L E + ++ QK V EL
Sbjct: 1777 LSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG 1836
Query: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
+LE R A + + LE+ +L + + ++ + KL+ +VQ + +
Sbjct: 1837 ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEV 1896
Query: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319
E + K K Q+E+ V AE + KL ++Q+
Sbjct: 1897 AETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQE 1945
Score = 111 bits (278), Expect = 6e-24
Identities = 110/542 (20%), Positives = 225/542 (41%), Gaps = 61/542 (11%)
Query: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
ED ++ R Q+A + +++ L ++ LQ +L + RL K+
Sbjct: 1399 EDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQ 1458
Query: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
+ + L + + + EE + Q E + ++ ++L L+ EE ++ L+ E +
Sbjct: 1459 LQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQ 1518
Query: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE------------------ 1019
+I L +++ ++ K +KL+EE +++ L E E
Sbjct: 1519 EEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELL 1578
Query: 1020 -----------EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFH 1068
EK + + + K + I L+ L E KSR E+ +LK+K+E D ++
Sbjct: 1579 EAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEME 1638
Query: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1128
Q++ Q++E L + + +++ +LDD ++ +++ E S LQ +L+
Sbjct: 1639 LQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELE 1698
Query: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETR 1188
R+ + + E+ +R L EE E L+ L T L K++ E V + + E
Sbjct: 1699 DLRSLQEQTERGRR-LSEE-ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEV 1756
Query: 1189 SHEAQ-VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--------------------- 1226
E Q +E +K A L+E+L++ + A+L++ +
Sbjct: 1757 VQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMA 1816
Query: 1227 --------QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
Q LE +L GEL + E + ++LE ++EL + + ++ + +
Sbjct: 1817 LMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRM 1876
Query: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
++ KLQ +V++ + AE +A + +L + +E + Q + K
Sbjct: 1877 QTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKA 1936
Query: 1339 RQ 1340
R+
Sbjct: 1937 RE 1938
Score = 37.4 bits (85), Expect = 0.15
Identities = 27/137 (19%), Positives = 65/137 (47%), Gaps = 3/137 (2%)
Query: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
++ + ++QK + R ++ E EL+ ++ ++ L+ ++ EL +AEE
Sbjct: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869
Query: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
+ L+ + +++++ +++ ++ E Q K +Q +L E E E A ++
Sbjct: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929
Query: 970 QLEKVTAEAKIKKLEDE 986
K+ A KK+++E
Sbjct: 1930 NKLKIKAREFGKKVQEE 1946
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 607 bits (1565), Expect = e-173
Identities = 439/1419 (30%), Positives = 719/1419 (50%), Gaps = 139/1419 (9%)
Query: 36 VWVPSEKQGFEAASIKEEK--GDEVVVELVENGKKV--TVGKDDIQKM-NPPKFSKVEDM 90
VW+P ++ +++A I ++ GD+V+ L+E+G ++ +V + + + NP D+
Sbjct: 13 VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72
Query: 91 AELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHE 149
L+ L+E +VLHNLR R+ S LIYTYSG+ V +NPYK LPIY + I+ Y G+ +
Sbjct: 73 TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132
Query: 150 MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
M PHI+A+A+ AY+ M ++ +QSI+ +GESGAGKT + + ++Y A V+ S
Sbjct: 133 MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----- 187
Query: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
+E ++L +NPI EA GNAKT +NDNSSRFGK+ I+FD I+GAN+ TYLLEKS
Sbjct: 188 --AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKS 245
Query: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLL---EGFNNYTFLSNGFVPIPAAQDDEMF 326
R + Q+ +ER +HIFY + A A++ L L E F NYT + V I D
Sbjct: 246 RVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEF-NYTRMGGNTV-IEGVNDRAEM 303
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
ET + ++GF E+ Q+ + K+++++L LGN+ N + D++ + C L+G
Sbjct: 304 VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLG 363
Query: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
+ + + +I + V K T+ QA A +ALAK Y LF +I+ R+N+AL
Sbjct: 364 LESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQF 423
Query: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
+ +Q +F+G+LDI GFE F+VNSFEQ CINY NEKLQQ FN +F LEQEEY +E I W
Sbjct: 424 SGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
Query: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE-QGSHPKFQK 565
IDF D QP I+LIE G+L LLDEEC P TD+++++KL +P F+K
Sbjct: 483 TLIDF-YDNQPVIDLIEA---KMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEK 538
Query: 566 PKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
P+ T F I H+A KV+Y +L KN D + D + +L AS A+ +++ +
Sbjct: 539 PRM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQE-NPT 595
Query: 626 VGLDQMAKMTESSLPSASKTKKGMFR-TVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHE 684
+ +T S K FR TVG ++ L LM TL TTP++VRCI PN E
Sbjct: 596 PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
Query: 685 KRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGK 744
K + D+ +++QLR GVLE IRI Q +P+R + EF RY IL F D K
Sbjct: 656 KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDKK 714
Query: 745 QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARK 804
+ C +++ L D N Y+ G++KIFFR G +A+LE+ R K+ + Q RG+L RK
Sbjct: 715 EVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRK 774
Query: 805 AFAKRQQ-----------QLTAMK--------------VIQRNCAAYLKLRNWQWWRLFT 839
F + ++ Q T K +IQ++C YL +Q R+ T
Sbjct: 775 KFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMAT 834
Query: 840 KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
+T Q R A +++ ++H + +LQ+ +A
Sbjct: 835 -------ITMQ-------------AYSRGFLARRRYRKMLEEHKAV-----ILQKYARA- 868
Query: 900 TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
A +R +L + ++ +LE++ L + +A E++
Sbjct: 869 --WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKI 926
Query: 960 EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
++ EA +K + E K K+ D + +++ KL K LE + + L E+
Sbjct: 927 QKLEAELEKAATHRRNYEEKGKRYRDAV---EEKLAKLQKHNSELETQKEQIQLKLQEKT 983
Query: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
E +LK K +++ +L ++KEE+ R LEK E D+ +QI L+ +I
Sbjct: 984 E------ELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLKEEIK 1034
Query: 1080 EL---KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARN 1135
L KMQL E L E+A+ + +K I E E I LQ + +D E+
Sbjct: 1035 ALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK---- 1090
Query: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK------REQEVTVLKKALDEETRS 1189
+ QKR++ E++ + +L ++ D + L + + E+ + L + TR
Sbjct: 1091 HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRV 1150
Query: 1190 HEAQVQEMRQKHAQAVE-------ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV 1242
E+ Q + + + +E L++++ ++ + +++ E L E +
Sbjct: 1151 LESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMM 1210
Query: 1243 LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
+ KQ++ +LE Q Q+L+ + LN++ K++ ++E ++ L+ ++
Sbjct: 1211 IPDFKQQI----SELEKQKQDLEIR----------LNEQAEKMKGKLEELSNQLHRSQ-- 1254
Query: 1303 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
++ + L+ E+ T++K + K+++++E + L+ Q + E E K N
Sbjct: 1255 -----EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNF 1306
Query: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1401
+ S L ++ D +++L ++ L++ K K I
Sbjct: 1307 RQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345
Score = 89.7 bits (221), Expect = 2e-17
Identities = 97/507 (19%), Positives = 217/507 (42%), Gaps = 51/507 (10%)
Query: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1509
+R+F + NI Y +R + + E + KE L AL A + +E+ K L
Sbjct: 872 RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGD-VEKIQK-L 929
Query: 1510 KAEMEDLVSSK-----------DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
+AE+E + + D V + + +L+K LETQ E+++ +L+E +EL+
Sbjct: 930 EAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKE- 988
Query: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
M L Q D+Q + Q + + + +YE +++ +++
Sbjct: 989 ---------KMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDE 1039
Query: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
K +L+ ++ + +D G + + +L K + +F++E+E +A + ++ +
Sbjct: 1040 KMQLQHLVEGEHVTSD----GLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQ 1095
Query: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
+++ + +++ + + E R + +E E E L+ R LE+
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155
Query: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN---- 1794
++ E+E +EA++ +V +Q+ L E NES R ++ R
Sbjct: 1156 QSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDI---NESIRHEVTRLTSENM 1209
Query: 1795 -----KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
K+ S+L + + ++ + ++ K+ +L Q+ + E+ K+L+ +++
Sbjct: 1210 MIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE 1269
Query: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE---EAEEESQRINANRRKLQRE 1906
+ +++ K+ ++ +E E + KQ + + E +E+ R+ R L+ E
Sbjct: 1270 ------IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEE 1323
Query: 1907 LDEATESNEAMGREVNALKSKLRRGNE 1933
LD + + +V L + + N+
Sbjct: 1324 LDMKDRVIKKLQDQVKTLSKTIGKAND 1350
Score = 79.7 bits (195), Expect = 3e-14
Identities = 106/476 (22%), Positives = 205/476 (43%), Gaps = 77/476 (16%)
Query: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
QL LQ +L+++ + L +++L + +K+Q + +E ++ +++
Sbjct: 886 QLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEE 945
Query: 1400 EIENLTQQYEEKAAAYDK--------LEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQ 1450
+ + EEK A K E+ + +LQ++ ++L +DN +QL +++K++
Sbjct: 946 KGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEE 1005
Query: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR-ALEEALEA--------KEE 1501
R Q + EK+ K D + ++ ++E KAL + L+ +E K E
Sbjct: 1006 R---QRMLLEKSFELKTQDY--EKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAE 1060
Query: 1502 LERTNKMLKA------EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE----- 1550
+ R +K +K E+E L + K DV K+V + KR + +M E+ QL E
Sbjct: 1061 VARLSKQVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLESYDIE 1117
Query: 1551 -------LEDELQATEDAKL------------RLEVNMQALKGQFERDLQARDEQNEEKR 1591
+ED ED +L LE + Q+ K +E++++A + +
Sbjct: 1118 DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLS 1177
Query: 1592 RQLQ--RQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQ-ADSAIKGREEAI 1644
+++ ++L E ++ + + ++ + D K +LE Q D I+ E+A
Sbjct: 1178 QEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAE 1237
Query: 1645 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704
K KL+ R E+ R + A +NE K E + ++QE A++ +K
Sbjct: 1238 KMKGKLEELSNQLHRSQEEEGTQRKALEA---QNEIHTKEKEKLIDKIQEMQEASDHLKK 1294
Query: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
Q + E E + E RL LEEEL+ + ++ + D+V+
Sbjct: 1295 QFETESEVKCN-----------FRQEASRLTLENRDLEEELDMKDRVIKKLQDQVK 1339
Score = 56.6 bits (135), Expect = 2e-07
Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 14/172 (8%)
Query: 849 RQEEEMQAKEDELQ-KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
+Q E++ ++ +L+ + E+ +K + +L+EL + + EE+ ++ L+A+ E++ + +
Sbjct: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275
Query: 908 EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
E +L K QE++E ++ + E E + + E ++ + DLEE+L+ ++ +
Sbjct: 1276 E---KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIK 1332
Query: 968 KLQLEKVTAEAKIKKLED--------EILVMDDQNNKLSKERKLLEERISDL 1011
KLQ + T I K D E L M K E KL++ I DL
Sbjct: 1333 KLQDQVKTLSKTIGKANDVHSSSGPKEYLGM--LQYKREDEAKLIQNLILDL 1382
Score = 53.1 bits (126), Expect = 3e-06
Identities = 54/269 (20%), Positives = 125/269 (46%), Gaps = 23/269 (8%)
Query: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE--LA 1714
+++ LE+ +A + +A A ++ +S+ ++ +Q +K D KE L
Sbjct: 850 YRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909
Query: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
E+L S + R ++ ++LEA + + + + D V + + ++ ++EL
Sbjct: 910 EKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELE 969
Query: 1775 TERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1834
T++ E + +L+ + +EL+ K M+ K F + E + LE+ E +
Sbjct: 970 TQK------EQIQLKLQEKTEELKEK---MDNLTKQLFDD-VQKEERQRMLLEKSFELKT 1019
Query: 1835 REKQAATKSLKQKDKKLKEILLQ----VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
++ + +SLK++ K LK+ +Q VE E ++ K + + + +VK + +E E
Sbjct: 1020 QDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIE 1079
Query: 1891 -------EESQRINANRRKLQRELDEATE 1912
+ + + + +R+++ ++ E T+
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITK 1108
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 600 bits (1548), Expect = e-171
Identities = 463/1688 (27%), Positives = 847/1688 (50%), Gaps = 180/1688 (10%)
Query: 26 AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
A+ W VW+ + GF AS +K E+ + +V V+L +G + V +DD++K N
Sbjct: 342 AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
Query: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
P ++ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +YSEK++
Sbjct: 401 APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
Query: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
M+KG +R +M PHIYA+A TAYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 461 MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
Query: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
G K S+ ++ +LEAFGN+ T+ N N++RF + + ++FD G + A+
Sbjct: 521 I-SGNKVFSV-----EKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574
Query: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320
I+T LLEK R R+ E TF++FYY++A +R++L L N+ +N F +P A
Sbjct: 575 IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630
Query: 321 QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RNTDQASMP 373
+ +E F + AM ++G S +EQ + +++++ LG KE +
Sbjct: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
Query: 374 DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT----------------KEQA 417
+ AQK +L+G ++ + + +I + K G +Q++ + K A
Sbjct: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748
Query: 418 DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471
+E +A Y LF +++ VN+AL + S + I+D GF+ E SF
Sbjct: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
Query: 472 EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------GLDLQPCI 519
E+LC NYT ++LQ+LF+ F+ E E Y+ E IE F D Q +
Sbjct: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
Query: 520 ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQLKDKTEFS 576
+ R + G+L LL+EE P A++ + +E+L + G K Q P K
Sbjct: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
Query: 577 II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624
++ H V+YN + WL +P N LL S K +++L+
Sbjct: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
Query: 625 IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
I GL+ +++ S KT GM +++ K Q+ L+ T++ + +FV C
Sbjct: 988 IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047
Query: 680 IPNHEKRSG-----------------------------KLDAFLVLEQLRCNGVLEGIRI 710
+P E +G +LD L+ QLR + +L+ +R+
Sbjct: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107
Query: 711 CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765
RQG+P+ +VF EFR+R+++LA + K +D ++A +++ L+L+ + +G
Sbjct: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167
Query: 766 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
S++FFR G LA LEE+RD + + + FQA CRGYLAR+ F KR+ Q A++ +Q+N
Sbjct: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227
Query: 826 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-------L 878
+++W WW+LFT V+PL++V EE+++ K++E+Q+ + + +KAE E E L
Sbjct: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287
Query: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
E + S+LT E L E+ E+ E RL A+K E++E+ + +A ++ E
Sbjct: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344
Query: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995
++ R A ++ ++++++A + +L+ E+ E K+L+ E +D+
Sbjct: 1345 MEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLE 1398
Query: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052
+ ++ LE R+ DL A+ EE + L +LK K + + +EL+ + L+ ++ E
Sbjct: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
Query: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110
LEK +R+ + + S HE +AQ +L+ + ++E+++ A A L ++ +K+ +
Sbjct: 1456 LEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510
Query: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
+K+ LE + D+ + A+ K +KQ RDL +++ + EL++ + ++
Sbjct: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570
Query: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
+ + E E+ +++ +E S + +V+E RQ + ++++ QLE+ ++KQ
Sbjct: 1571 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY-------EDKQ 1623
Query: 1228 TLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
+ +E +L G+L L Q + +K+L ++ ++ +D + L + +
Sbjct: 1624 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-K 1682
Query: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
E+ + L E+E K ++ +++D + + + K + +L +L+ E+N
Sbjct: 1683 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1742
Query: 1347 SLQDQLDEEMEAKQNL-ERHISTLN------IQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
+Q++L+E+ E L ++H + + Q++D + +L++ + L+E + Q
Sbjct: 1743 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1802
Query: 1400 EIENLTQQYEEKAAA---YDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456
++E L Q +K+ K+ + + RL+ E + +L N+EK + DQ
Sbjct: 1803 QVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQR 1862
Query: 1457 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
+A E ++ ++ R + + R+ + + LAR EA K ELE + L+A + L
Sbjct: 1863 IAAE----NREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
Query: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
+ K + +L+ A+E +ME +E ED + + +D + + L+G
Sbjct: 1919 QADLKLAFKRIGDLQ---AAIEDEMES-----DENEDLINSLQDMVTKYQKRKNKLEGDS 1970
Query: 1577 ERDLQARD 1584
+ D + D
Sbjct: 1971 DVDSELED 1978
Score = 231 bits (589), Expect = 5e-60
Identities = 189/738 (25%), Positives = 372/738 (50%), Gaps = 61/738 (8%)
Query: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
N+ KNK + L +R L + + E + K E ++Q+L+SK E+ R EL
Sbjct: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
Query: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
+L++ + +T L + + +LL ET ++L ++++
Sbjct: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
Query: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379
L+ + ++L+ Q++ EME + + +N ++ D +KK+
Sbjct: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
Query: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
LQ +F +E ++ K++ ++ + +L EE A +L+K RL EL D + L+
Sbjct: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
Query: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Q+ LEKKQR+FD L++ + + +R++ + E +A SL + LEE
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Query: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
+ L+AE++D+ S + ++ +++K R LE ++++ + +L+E +Q
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
E AKLRLE+ M+ ++ +++++RDE+ EE R+ Q++L + E +LE+E + +
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
K++LEG L L +D + E+ K+LRK +K + L DA+ D + +A +
Sbjct: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSA-PS 1681
Query: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
+++ L+ L + + AAA +ARK ++E E+L ++ + AL+++ RL+
Sbjct: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
Query: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
+++ LEE+Q +M + + + A QA + ++ ++ ++ +Q+L+ + + L+
Sbjct: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
Query: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858
S++ +E ++ KS ++ EAKI +LE ++E E R + +SL + K+ E L +
Sbjct: 1802 SQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
Query: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913
D+R AE +++ K+L+RQL + +EE + A+R+K + E+D ES
Sbjct: 1859 RDQRIAAENREKEQN------KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
Query: 1914 NEAMGREVNA-LKSKLRR 1930
EA + + A LK +R
Sbjct: 1911 LEAANQSLQADLKLAFKR 1928
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 598 bits (1543), Expect = e-170
Identities = 462/1684 (27%), Positives = 838/1684 (49%), Gaps = 187/1684 (11%)
Query: 26 AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
A+ W VW+ + GF AS +K E+ + +V V+L +G + V +DD++K N
Sbjct: 342 AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
Query: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
P ++ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +YSEK++
Sbjct: 401 APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
Query: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
M+KG +R +M PHIYA+A TAYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 461 MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
Query: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
G K S+ ++ +LEAFGN+ T+ N N++RF + + ++FD G + A+
Sbjct: 521 I-SGNKVFSV-----EKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574
Query: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320
I+T LLEK R R+ E TF++FYY++A +R++L L N+ +N F +P A
Sbjct: 575 IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630
Query: 321 QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RNTDQASMP 373
+ +E F + AM ++G S +EQ + +++++ LG KE +
Sbjct: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
Query: 374 DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT----------------KEQA 417
+ AQK +L+G ++ + + +I + K G +Q++ + K A
Sbjct: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748
Query: 418 DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471
+E +A Y LF +++ VN+AL + S + I+D GF+ E SF
Sbjct: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
Query: 472 EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------GLDLQPCI 519
E+LC NYT ++LQ+LF+ F+ E E Y+ E IE F D Q +
Sbjct: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
Query: 520 ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQLKDKTEFS 576
+ R + G+L LL+EE P A++ + +E+L + G K Q P K
Sbjct: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
Query: 577 II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624
++ H V+YN + WL +P N LL S K +++L+
Sbjct: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
Query: 625 IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
I GL+ +++ S KT GM +++ K Q+ L+ T++ + +FV C
Sbjct: 988 IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047
Query: 680 IPNHEKRSG-----------------------------KLDAFLVLEQLRCNGVLEGIRI 710
+P E +G +LD L+ QLR + +L+ +R+
Sbjct: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107
Query: 711 CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765
RQG+P+ +VF EFR+R+++LA + K +D ++A +++ L+L+ + +G
Sbjct: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167
Query: 766 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
S++FFR G LA LEE+RD + + + FQA CRGYLAR+ F KR+ Q A++ +Q+N
Sbjct: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227
Query: 826 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-------L 878
+++W WW+LFT V+PL++V EE+++ K++E+Q+ + + +KAE E E L
Sbjct: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287
Query: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
E + S+LT E L E+ E+ E RL A+K E++E+ + +A ++ E
Sbjct: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344
Query: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995
++ R A ++ ++++++A + +L+ E+ E K+L+ E +D+
Sbjct: 1345 MEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLE 1398
Query: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052
+ ++ LE R+ DL A+ EE + L +LK K + + +EL+ + L+ ++ E
Sbjct: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
Query: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110
LEK +R+ + + S HE +AQ +L+ + ++E+++ A A L ++ +K+ +
Sbjct: 1456 LEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510
Query: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
+K+ LE + D+ + A+ K +KQ RDL +++ + EL++ + ++
Sbjct: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570
Query: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
+ + E E+ +++ +E S + +V+E RQ + ++++ QLE+ ++KQ
Sbjct: 1571 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY-------EDKQ 1623
Query: 1228 TLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
+ +E +L G+L L Q + +K+L ++ ++ +D + L + +
Sbjct: 1624 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-K 1682
Query: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
E+ + L E+E K ++ +++D + + + K + +L +L+ E+N
Sbjct: 1683 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1742
Query: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
+Q++L+E+ E L + Q S ++ D + +E + K+ Q++++ L
Sbjct: 1743 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1802
Query: 1407 QYE-EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1465
Q E + + DK +R + ++ +L L+ +R V LE L + K
Sbjct: 1803 QVEFLEQSMVDK--SLVSRQEAKIRELETRLEFERTQVKRLE-------SLASRLKENME 1853
Query: 1466 KYADERD-RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
K +ERD R AE REK E + L+R + K EM +L + +
Sbjct: 1854 KLTEERDQRIAAENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEAS 1898
Query: 1525 KNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
+ HELE +LE + ++ L+ + +LQA + ++ + N + + + D+
Sbjct: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD 1958
Query: 1582 ARDE 1585
+ E
Sbjct: 1959 SELE 1962
Score = 231 bits (589), Expect = 5e-60
Identities = 189/738 (25%), Positives = 372/738 (50%), Gaps = 61/738 (8%)
Query: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
N+ KNK + L +R L + + E + K E ++Q+L+SK E+ R EL
Sbjct: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
Query: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
+L++ + +T L + + +LL ET ++L ++++
Sbjct: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
Query: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379
L+ + ++L+ Q++ EME + + +N ++ D +KK+
Sbjct: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
Query: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
LQ +F +E ++ K++ ++ + +L EE A +L+K RL EL D + L+
Sbjct: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
Query: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Q+ LEKKQR+FD L++ + + +R++ + E +A SL + LEE
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Query: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
+ L+AE++D+ S + ++ +++K R LE ++++ + +L+E +Q
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
E AKLRLE+ M+ ++ +++++RDE+ EE R+ Q++L + E +LE+E + +
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
K++LEG L L +D + E+ K+LRK +K + L DA+ D + +A +
Sbjct: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSA-PS 1681
Query: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
+++ L+ L + + AAA +ARK ++E E+L ++ + AL+++ RL+
Sbjct: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
Query: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
+++ LEE+Q +M + + + A QA + ++ ++ ++ +Q+L+ + + L+
Sbjct: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
Query: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858
S++ +E ++ KS ++ EAKI +LE ++E E R + +SL + K+ E L +
Sbjct: 1802 SQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
Query: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913
D+R AE +++ K+L+RQL + +EE + A+R+K + E+D ES
Sbjct: 1859 RDQRIAAENREKEQN------KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
Query: 1914 NEAMGREVNA-LKSKLRR 1930
EA + + A LK +R
Sbjct: 1911 LEAANQSLQADLKLAFKR 1928
Score = 161 bits (408), Expect = 5e-39
Identities = 172/771 (22%), Positives = 348/771 (45%), Gaps = 83/771 (10%)
Query: 1069 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
EQI + +I +L+ +L K E+E L+ RL+ I++ + L R S L
Sbjct: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
Query: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
LD+E A R +AEK+ ++L + +ALK ++E + E+ R + +D+
Sbjct: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
Query: 1186 ETRSHEAQVQEMRQKHAQAVEELT---EQLEQFKRAKANLDK-NKQTLEKENADLAGELR 1241
+ E R K+ +AV E+ ++L+Q K +++ NK+ LE+ DL +
Sbjct: 1365 DDAGGE-----WRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSE 1419
Query: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301
+A Q+++ K ++L A++Q+ + + EL K + +E+ +
Sbjct: 1420 ESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKL 1479
Query: 1302 KAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQN 1361
+ KL ++ L ++ ++ L+E+ + K+ LE E + Q ++ +
Sbjct: 1480 QREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
Query: 1362 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK-LEK 1420
+++ + L ++ D +++L + A T++ LE+ K R + E+E + Q + ++ + D+ +E+
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
Query: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1480
+ Q++L + V L+ + E KQ+ +L E++ + K A D+ E
Sbjct: 1600 ARQSCQKKLKQMEVQLEEE------YEDKQK----VLREKRELEGKLATLSDQVNRRDFE 1649
Query: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
E + +++L+RT KA + D D + K+ + +
Sbjct: 1650 SEKRL-------------RKDLKRT----KALLADAQLMLDHL--------KNSAPSKRE 1684
Query: 1541 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
+ ++K QLEE E A A+ +EV ++ L Q + D+ EE+ +LQR+ +E
Sbjct: 1685 IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID-DIAKAKTALEEQLSRLQREKNE 1743
Query: 1601 YETELEDE--------RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1652
+ LE++ +K +A A A + L + DL+ Q + A K ++E ++L+ LQ+
Sbjct: 1744 IQNRLEEDQEDMNELMKKHKAAVAQASRDL-AQINDLQAQLEEANKEKQELQEKLQALQS 1802
Query: 1653 QMKDFQRELED-ARASRDEIFATAKENE--------KKAKSLEADLMQLQEDLAAAERAR 1703
Q++ ++ + D + SR E E K+ +SL + L + E L R
Sbjct: 1803 QVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQR 1862
Query: 1704 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIA----QLEEELEEEQGNMEAMSDRV 1759
A+ ++E + L L E R EA + +LE +LE + +++ +
Sbjct: 1863 IAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADL 1922
Query: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
+ A ++ L + E + + + + + ++ S+L + VKS
Sbjct: 1923 KLAFKRIGDLQAAIEDEMESDENEDLINSE---GDSDVDSELEDRVDGVKS 1970
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 598 bits (1542), Expect = e-170
Identities = 463/1469 (31%), Positives = 743/1469 (50%), Gaps = 111/1469 (7%)
Query: 36 VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
VW+P ++ +++A + ++ GD+V++ +E GK + D K NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V +NPY+ LPIY E I++ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
+M PHI+A+A+ AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
Query: 208 TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
+ +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE
Sbjct: 187 -ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245
Query: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDD-EMF 326
KSR + QA +ER +HIFY + A AK L L +N+ + G P+ DD +
Sbjct: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV-CHLM 385
T +A ++G SE Q+ I ++++ +L LGN+ F R+ D ++P + C LM
Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364
Query: 386 GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
G++ + + ++ + K +K QA A +ALAK Y +LF WI+ VN+AL
Sbjct: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
Query: 446 KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
+Q SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483
Query: 506 WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQGSHPKFQ 564
W IDF D QPCI LIE + G+L LLDEEC PK TD ++ +KL T F+
Sbjct: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 565 KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
KP+ L +K F I H+A KV+Y +L KN D + + +L +S K + +L++D ++
Sbjct: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
Query: 625 IVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTLRNTTPNF 675
+ + L + +K KG +TVG ++ L LM TL TTP++
Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
Query: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
VRCI PN K D ++QLR GVLE IRI GFP+R +QEF RY +L
Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716
Query: 736 IPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 795
D KQ C +++ L LD + Y+ G++KIFFR G +A+LE+ R K+ + Q
Sbjct: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775
Query: 796 MCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLFTKVKPLL 845
RG+L RK + + R+ +T + + Q C A R ++WR++
Sbjct: 776 TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY------- 828
Query: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
V R+ +++ + ++ R A N +++ ++H + +K + + +
Sbjct: 829 -VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
Query: 906 A---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLDLEEQLEE 961
A + R K+EL+++ ++EAR E R ++L K+ Q ++EQ ++
Sbjct: 888 AIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRKVDEQNKD 942
Query: 962 EEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDLTTNLAEE 1018
+ +KL + ++ +KL ++ L + ++ K++ R L L+E I+ L +L +
Sbjct: 943 YKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQT 1002
Query: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
+ K + + ++++ +L LK+E +QE E L ++ A + E +
Sbjct: 1003 RSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETM------ 1056
Query: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
E K+ K+ EL L+DE + N L + LE DL+E++
Sbjct: 1057 --EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPG 1109
Query: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQE 1196
K+ + E E S + E R +E + K LD + +V E
Sbjct: 1110 HKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQEVEHKKK 1255
+ Q+ +EL + EQ R+KA E+E + G EL +QE+E + K
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQELESENK 1216
Query: 1256 KLEAQVQELQSKCSDGERARAELN-DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
KL+ ++ EL+ S E++ E+ + +E +T + E + + ++V L
Sbjct: 1217 KLKNELNELRKALS--EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVR----KEEVLILR 1270
Query: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
SQL +E +Q + N T L E+ ++D+ E +A L+ L QL
Sbjct: 1271 SQLVSQKEAIQ--PKDDKNTMTDSTILLEDVQKMKDK-GEIAQAYIGLKETNRLLESQLQ 1327
Query: 1375 DSKKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
K+ ++ A +++L+E R Q+++ Q +A L+ RL E
Sbjct: 1328 SQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQNLQLPPEARIEASLQHEITRLTNENL 1386
Query: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
DL+ L+ Q + V L+K+ + F + + E
Sbjct: 1387 DLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415
Score = 88.6 bits (218), Expect = 6e-17
Identities = 144/665 (21%), Positives = 264/665 (39%), Gaps = 113/665 (16%)
Query: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
AK+E+ KK K+EA+ E K G + +K+ +LQ +V+
Sbjct: 901 AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940
Query: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
KD L +L + + + ET +KL + QL EE EAK R
Sbjct: 941 --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985
Query: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1424
+S L +++ +K L+ S + +EE R+++E E L EE + E +R
Sbjct: 986 LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044
Query: 1425 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
+ Q+ ++ ++ + +QL +L ++ ++ LL E + +Y D ++
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104
Query: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1538
+ ++ + E E AEMED+ S ++ + L+ S L+
Sbjct: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159
Query: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
++ E++ + + ++DEL E+ LR + EE+R Q++
Sbjct: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198
Query: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1656
ELE E +R + KKL+ +L +L L SA + R L Q+
Sbjct: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
Query: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
EL D R I + ++K+A + D + + E +K D K E+A+
Sbjct: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311
Query: 1717 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE 1776
L++ R LE+++ + E E AE L E+
Sbjct: 1312 YIG-------LKETNRLLESQLQSQKRSHENE-----------------AEALRGEI--- 1344
Query: 1777 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
+ ++ + +QQL QN +L E +++ + I L + L EQ+E++ +
Sbjct: 1345 -QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQDKT 1398
Query: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEEESQ 1894
+ K LK KK+ E+ + + + E N + K + LE +E+ Q
Sbjct: 1399 VRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1458
Query: 1895 RINAN 1899
++ N
Sbjct: 1459 KLVKN 1463
Score = 82.4 bits (202), Expect = 4e-15
Identities = 108/531 (20%), Positives = 220/531 (41%), Gaps = 65/531 (12%)
Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1252
M ++ + ++ +E++K+ ++ ++ ++++N D + L +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1253 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
+ +KL + ++ LQ + + A L +++ KL+ ++E E A + ++
Sbjct: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
Query: 1310 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1359
L S L++ LL++E ++ LN T ++L EE L+ L++E
Sbjct: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
Query: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1416
QNL S L + D K+++ V + G KR + +Y E A D
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135
Query: 1417 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
+T+ ++++ D+ + L Q+++ ++KQ D+L +E+ + A E +R +
Sbjct: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195
Query: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAE----------------MEDLVSS 1519
E E ++L E + K EL K L + ME L S
Sbjct: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV 1255
Query: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
+++ E+ L +Q+ K ++ +D+ T+ L +V KG+ +
Sbjct: 1256 SEELDVRKEEV----LILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQA 1311
Query: 1580 LQARDEQNE--EKRRQLQRQLHEYETEL----------EDERKQRALA--------AAAK 1619
E N E + Q Q++ HE E E E+ R+Q+ LA A +
Sbjct: 1312 YIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE 1371
Query: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1670
L+ ++ L + ++ E+ K +RKL+ Q+K F +++ + + E
Sbjct: 1372 ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQME 1422
Score = 68.2 bits (165), Expect = 8e-11
Identities = 87/393 (22%), Positives = 168/393 (42%), Gaps = 48/393 (12%)
Query: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
+R +R+L + + E + + L +E + L+ + D K + +++L
Sbjct: 897 RRMMAKRELKKLKIEARSVERYKKLHIG----MENKIMQLQRKVDEQNKDYKCLVEKLTN 952
Query: 1650 LQ----AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK- 1704
L+ ++ + + +LE + S +E AK + SL+ ++ +L++DL +K
Sbjct: 953 LEGIYNSETEKLRSDLERLQLSEEE----AKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
Query: 1705 ---QADLEKEELAEELASSLSGRNAL-QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
AD K+E E+L S+L N L + EK L RI Q +E+ E ME +
Sbjct: 1009 IEEHADRYKQE-TEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------K 1058
Query: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA-- 1818
K ++ +QL +L ER Q + +LE + +L+ ++ M K K T +
Sbjct: 1059 KLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS 1118
Query: 1819 -------LEAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1868
++IA++E+ + E+ + +K SL K L++ + ++E E+++ +
Sbjct: 1119 SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK---LQKRVTELEQEKQVMQDE 1175
Query: 1869 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
++ E+ Q+ R + EE Q A + E N+ + E+N L+ L
Sbjct: 1176 LDRKEE------QVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKAL 1229
Query: 1929 RRGNETSFVPSRRSGGRRVIENADGSEEETDTR 1961
+ R ++E EE D R
Sbjct: 1230 SEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVR 1262
Score = 65.1 bits (157), Expect = 7e-10
Identities = 85/470 (18%), Positives = 187/470 (39%), Gaps = 56/470 (11%)
Query: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
E + + EAR E + ++ + +++ NK K +E L + + +
Sbjct: 904 ELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEK 963
Query: 1530 LEKSKRALETQMEEMKT----------QLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
L L+ EE K ++ +L +L+ T K +E + K + E+
Sbjct: 964 LRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023
Query: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
+ E+N +++ + H + ++ + +KKL + K LEL +
Sbjct: 1024 VSNLKEENTLLKQEKEALNHRIVQQAKE------MTETMEKKLVEETKQLELDLNDERLR 1077
Query: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
+ + + +L+ + D + E+ + K K+ S + E + ++
Sbjct: 1078 YQNLLNEFSRLEERYDDLKEEMT-------LMVHVPKPGHKRTDSTHSS--NESEYIFSS 1128
Query: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
E A + + E E L L +L+ R+ +LE+E + Q ++ ++V
Sbjct: 1129 EIAEMEDIPSRTEEPSEKKVPLDMSLFL-----KLQKRVTELEQEKQVMQDELDRKEEQV 1183
Query: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA- 1818
++ + E+ E + RQ+LE +NK+L+++L+E+ A+ K + A
Sbjct: 1184 LRSKAKEEERPQIRGAE---LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAP 1240
Query: 1819 -------LEAKIAQLEEQVEQEARE-------KQAATKSLKQKDKK--------LKEILL 1856
L ++ + E+++ E + ++++ KD K L E +
Sbjct: 1241 GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ 1300
Query: 1857 QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
+++D+ ++A+ Y E QL+ Q E E++ + + L+ E
Sbjct: 1301 KMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEE 1350
Score = 51.2 bits (121), Expect = 1e-05
Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 9/147 (6%)
Query: 846 QVTRQEEEMQAKEDELQKTK-----ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
Q+ Q+E +Q K+D+ T E QK +++ E+ Q + L E LL+ QLQ++
Sbjct: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDK-GEIAQAYIGLKETNRLLESQLQSQK 1330
Query: 901 ELYA-EAEEMRVRLAAKKQE--LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 957
+ EAE +R + + K+E ++ L +L E LQ E ++ + LDL E
Sbjct: 1331 RSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLME 1390
Query: 958 QLEEEEAARQKLQLEKVTAEAKIKKLE 984
QLE+++ +KL+ + KI +LE
Sbjct: 1391 QLEKQDKTVRKLKKQLKVFAKKIGELE 1417
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 596 bits (1537), Expect = e-170
Identities = 462/1523 (30%), Positives = 751/1523 (49%), Gaps = 159/1523 (10%)
Query: 36 VWVPSEKQGFEAASI-KEEKGDEVVVELVENGKKVTVGKDDIQK------MNPPKFSKVE 88
VW+P + + +A + K+ K + ++L + + D+Q+ NP
Sbjct: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72
Query: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V +NPY+ LPIY + ++ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132
Query: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
+M PHI+A+A+ AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S +
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---ASE 189
Query: 208 TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
T+I E+++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN+ TYLLE
Sbjct: 190 TNI----EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLE 245
Query: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMF 326
KSR + QA DER +HIFY + A A +L L ++ + S G I D E F
Sbjct: 246 KSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDF 305
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM-PDNTAAQKVCHLM 385
++T +A ++G E Q+SI K+++S+L LG++ + ER+ D S+ P + C L+
Sbjct: 306 EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365
Query: 386 GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
G+ + + ++ + K + +Q A ALAK Y +LF WI+ +NKAL
Sbjct: 366 GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425
Query: 446 KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
+ +Q SF+G+LDI GFE FEVNSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 426 TSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484
Query: 506 WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQK 565
W IDF D QPCI+LIE G+L LLDEEC PK TD+++ +KL S FQK
Sbjct: 485 WTLIDF-YDNQPCIDLIEA---KLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540
Query: 566 PKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
P+ T F I+H+A KV+Y + +L KN D + + ++L AS VADL+ D
Sbjct: 541 PRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598
Query: 626 V-----GLDQMAKMT-ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
V G +K++ S+ P + K +TVG ++ L LM TL TTP++VRCI
Sbjct: 599 VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658
Query: 680 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739
PN EK D ++QLR GVLE IRI G+P+R + +F RY +L
Sbjct: 659 KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELA 717
Query: 740 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799
D K C +++ L DP+ ++ G++KIFFR G +A+LE+ R K + Q RG
Sbjct: 718 NTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRG 777
Query: 800 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 859
+L + K + A +QR C +L R + R L
Sbjct: 778 WLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVL--------------- 819
Query: 860 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 919
QKH ++ + Q +A + A M VR +
Sbjct: 820 --------------------QKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVR-----RT 854
Query: 920 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ--KLQLEKVTAE 977
++L E +A ++ RG + +++ + ++ +A R+ L++E +AE
Sbjct: 855 YRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAE 914
Query: 978 AKIKKL----EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
+K+L E++++ + + ++ +KE K L E++S T+ E E+ K +L + +
Sbjct: 915 -HLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKK--ELVHYQQ 971
Query: 1034 SMISELEVRLKKE-EKSRQELEKL--KRKLEGDA-----SDFHEQIADLQAQIAELKMQL 1085
S + +RL++E E R EL++ +RK+ DA + +++ADL+ + A LK
Sbjct: 972 SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLK--- 1028
Query: 1086 AKKEEELQAALARLDDEIAQKN------------------NALKKIRELEGHISDLQEDL 1127
+KE+ L + DE AQ + N +K+ +LE +L++++
Sbjct: 1029 DEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEM 1088
Query: 1128 ----DSERAARNKAEKQKRDLGEELEALKT-ELEDTLDSTATQQEL-RAKREQEVTVLKK 1181
+ RN + + + ++ T E+ DT D+ +E+ K ++TV K
Sbjct: 1089 TIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLK 1148
Query: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE-NADLAGEL 1240
+ +V+E+ Q+ + +L E+ EQ K + + ++ + NADLA
Sbjct: 1149 L--------QKRVRELEQERKKLQVQL-EKREQQDSKKVQAEPPQTDIDLDPNADLAYN- 1198
Query: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
+QE+E + KKL+ + EL+ +D +A N+ H + + L A
Sbjct: 1199 ---SLKRQELESENKKLKNDLNELRKAVAD----QATQNNSSHGSPDSYSLLLNQLKLAH 1251
Query: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
+ ++V L +Q+ + + N++ + E++ Q+ E
Sbjct: 1252 EELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVC 1311
Query: 1361 NLERHISTLNIQLSDSK-----KKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAA 1414
D + + L+ A +EA L+ ++E+E+L Q E
Sbjct: 1312 QTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEE 1371
Query: 1415 YDKLEKT-------------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
DK ++T + +QQE+ L + + ++LV LEK +RK L ++
Sbjct: 1372 MDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK----LKKQL 1427
Query: 1462 NISSKYADERDRAEAEAREKETK 1484
I K A + + A+A A+ + +
Sbjct: 1428 KIYMKKAQDLEAAQALAQSERKR 1450
Score = 85.9 bits (211), Expect = 4e-16
Identities = 125/543 (23%), Positives = 240/543 (44%), Gaps = 69/543 (12%)
Query: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EAQ 1193
NK + +R + E+ + KT E +T+T + ++E+ +++ E+T + +
Sbjct: 925 NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEE 984
Query: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL-----RVLGQAKQ 1248
V+ +R + +A E + R K L K LE+ENA L E ++L Q+K
Sbjct: 985 VESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD 1044
Query: 1249 EVEH---KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM----LNEAEG 1301
E K+ ++ +++E +S+ + + ++L + L++E+ + N +
Sbjct: 1045 EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQ 1104
Query: 1302 KAIKLAKDVASLS-SQLQDTQELLQ-------EETRQKLNVSTKL----RQLEEERNSLQ 1349
+++ + S+S S++ DT++ LQ E+ + V KL R+LE+ER LQ
Sbjct: 1105 SSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQ 1164
Query: 1350 DQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1408
QL++ E + + ++ +I L D L + + LE K+ + ++ L +
Sbjct: 1165 VQLEKREQQDSKKVQAEPPQTDIDL-DPNADLAYNSLKRQELESENKKLKNDLNELRKAV 1223
Query: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
++A T+N D L NQ +L E + RK + L+ + +S A
Sbjct: 1224 ADQA--------TQNNSSHGSPDSYSLLLNQLKLAHE-ELEVRKEEVLILRTQIVS---A 1271
Query: 1469 DERDRAEAEAREKETKALSLARA-----LEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1523
D+R A A S + E+A+EA + +TN K E ++ ++
Sbjct: 1272 DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS--KTEDWGYLNEDGEL 1329
Query: 1524 GKNVHELEKSKRALETQM-----------EEMKTQLEELEDELQATE-----------DA 1561
G L++ R LE Q+ E +K QLE L++E+ + +A
Sbjct: 1330 GLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEA 1389
Query: 1562 KLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
++ V + + E DL+ E+ E+ R+L++QL Y + +D +ALA + +K
Sbjct: 1390 QVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERK 1449
Query: 1621 KLE 1623
+ E
Sbjct: 1450 RHE 1452
Score = 80.9 bits (198), Expect = 1e-14
Identities = 155/658 (23%), Positives = 265/658 (40%), Gaps = 110/658 (16%)
Query: 1239 ELRVLGQAKQEVEHKKKK---LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295
EL+ L + EH K+ +E +V +LQ K + +K K +E SVT
Sbjct: 902 ELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE--------QNKEFKTLSEQLSVTTS 953
Query: 1296 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE 1355
E + +K + V S +DT LQEE ++ T+L++ ER L+D E
Sbjct: 954 TYTMEVERLK-KELVHYQQSPGEDTSLRLQEEVE---SLRTELQRAHSERKILEDAHSRE 1009
Query: 1356 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI--ENLTQ-QYEEKA 1412
+ + + N L D K++L + + L + K F + ENL + + EE+
Sbjct: 1010 KDELRKRVADLEQENALLKDEKEQLNN-----QILCQSKDEFAQNSVKENLMKKELEEER 1064
Query: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1472
+ Y L K ++L+Q D NL + Q +N S++ + E D
Sbjct: 1065 SRYQNLVKEYSQLEQRYD--------------NLRDEMTIIKQTPGHRRNPSNQSSLESD 1110
Query: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532
E E+AL+ EE+ + KA M+ V K + K V ELE+
Sbjct: 1111 SNYPSISTSEIGDT------EDALQQVEEIG----LEKAAMDMTVFLK--LQKRVRELEQ 1158
Query: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
++ L+ Q+E+ + Q D+K +V + + + D A N KR+
Sbjct: 1159 ERKKLQVQLEKREQQ------------DSK---KVQAEPPQTDIDLDPNADLAYNSLKRQ 1203
Query: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGD-------LKDLELQADSAIKGREEAIK 1645
+L+ + + + +L + RK A A G L L+L A ++ R+E +
Sbjct: 1204 ELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-AHEELEVRKEEVL 1262
Query: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
LR Q D QR L A + ++ N +K QED A Q
Sbjct: 1263 ILRT-QIVSAD-QRRLAGRNAEPNINARSSWPNSEKHVD--------QEDAIEAYHGVCQ 1312
Query: 1706 ADLEKEELAE-----ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
+ + E+ EL + G L+ R LEA++ E EEE +++A + ++
Sbjct: 1313 TNSKTEDWGYLNEDGELGLAYQG---LKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALK 1369
Query: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
+ + +Q + AQ +Q++ R E K + LE
Sbjct: 1370 EEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNE------------NLDLKELVEKLE 1417
Query: 1821 AKIAQLEEQVEQEAREKQ--AATKSLKQKDKKLKEILLQVEDERK------MAEQYKE 1870
+L++Q++ ++ Q A ++L Q ++K E+ QV +RK M E +KE
Sbjct: 1418 KNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475
Score = 62.0 bits (149), Expect = 6e-09
Identities = 70/369 (18%), Positives = 157/369 (42%), Gaps = 43/369 (11%)
Query: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
+A +K + R + +A ++ +MLKA E + + ++ L++
Sbjct: 863 KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE--LKALRIEARSAEHLKRLN 920
Query: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD----LQARDEQNEEK 1590
+E ++ +++ +++E E + + +L V + ER + + E+
Sbjct: 921 VGMENKVVQLQRKIDEQNKEFKTLSE---QLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977
Query: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQ 1646
+LQ ++ TEL+ +R + A + + +L+ DLE Q ++ +K +E +
Sbjct: 978 SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE-QENALLKDEKEQLNN 1036
Query: 1647 LRKLQAQMKD-----------FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
++ Q KD ++ELE+ R+ + + E++ +L ++ +++
Sbjct: 1037 --QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQT 1094
Query: 1696 LAAAERARKQADLEKEELAEELASSLSG--RNALQDEKR--------------RLEARIA 1739
Q+ LE + +++S G +ALQ + +L+ R+
Sbjct: 1095 PGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154
Query: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
+LE+E ++ Q +E + K Q ++ + N RQ+LE +NK+L++
Sbjct: 1155 ELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKN 1214
Query: 1800 KLHEMEGAV 1808
L+E+ AV
Sbjct: 1215 DLNELRKAV 1223
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 596 bits (1536), Expect = e-170
Identities = 464/1487 (31%), Positives = 745/1487 (50%), Gaps = 120/1487 (8%)
Query: 36 VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
VW+P ++ +++A + ++ GD+V++ +E GK + D K NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 89 DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V +NPY+ LPIY E I++ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 148 HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
+M PHI+A+A+ AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
Query: 208 TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
+ +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE
Sbjct: 187 -ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245
Query: 268 KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDD-EMF 326
KSR + QA +ER +HIFY + A AK L L +N+ + G P+ DD +
Sbjct: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305
Query: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV-CHLM 385
T +A ++G SE Q+ I ++++ +L LGN+ F R+ D ++P + C LM
Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364
Query: 386 GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
G++ + + ++ + K +K QA A +ALAK Y +LF WI+ VN+AL
Sbjct: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
Query: 446 KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
+Q SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN +F LEQEEY +E I
Sbjct: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483
Query: 506 WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQGSHPKFQ 564
W IDF D QPCI LIE + G+L LLDEEC PK TD ++ +KL T F+
Sbjct: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539
Query: 565 KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
KP+ L +K F I H+A KV+Y +L KN D + + +L +S K + +L++D ++
Sbjct: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597
Query: 625 IVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTLRNTTPNF 675
+ + L + +K KG +TVG ++ L LM TL TTP++
Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657
Query: 676 VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
VRCI PN K D ++QLR GVLE IRI GFP+R +QEF RY +L
Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716
Query: 736 IPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 795
D KQ C +++ L LD + Y+ G++KIFFR G +A+LE+ R K+ + Q
Sbjct: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775
Query: 796 MCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLFTKVKPLL 845
RG+L RK + + R+ +T + + Q C A R ++WR++
Sbjct: 776 TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY------- 828
Query: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
V R+ +++ + ++ R A N +++ ++H + +K + + +
Sbjct: 829 -VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
Query: 906 A---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLDLEEQLEE 961
A + R K+EL+++ ++EAR E R ++L K+ Q ++EQ ++
Sbjct: 888 AIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRKVDEQNKD 942
Query: 962 EEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDLTTNLAEE 1018
+ +KL + ++ +KL ++ L + ++ K++ R L L+E I+ L +L +
Sbjct: 943 YKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQT 1002
Query: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
+ K + + ++++ +L LK+E +QE E L ++ A + E +
Sbjct: 1003 RSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETM------ 1056
Query: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
E K+ K+ EL L+DE + N L + LE DL+E++
Sbjct: 1057 --EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPG 1109
Query: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQE 1196
K+ + E E S + E R +E + K LD + +V E
Sbjct: 1110 HKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQEVEHKKK 1255
+ Q+ +EL + EQ R+KA E+E + G EL +QE+E + K
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQELESENK 1216
Query: 1256 KLEAQVQELQSKCSD--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
KL+ ++ EL+ S+ A L ++ SV+ L+ + + + L + S
Sbjct: 1217 KLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQ 1276
Query: 1314 SSQLQD-------TQELLQEETRQKLNVSTKLRQL-----EEERNSLQD--QLDEEME-- 1357
+Q T + E QK+ ++ Q E R+S D +L+E+ E
Sbjct: 1277 KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELW 1336
Query: 1358 -AKQNLERHISTLNIQLSDSKKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKA 1412
+ L++ L QL K+ ++ A +++L+E R Q+++ Q +A
Sbjct: 1337 LVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQNLQLPPEA 1395
Query: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
L+ RL E DL+ L+ Q + V L+K+ + F + + E
Sbjct: 1396 RIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
Score = 91.7 bits (226), Expect = 7e-18
Identities = 144/668 (21%), Positives = 271/668 (40%), Gaps = 92/668 (13%)
Query: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
AK+E+ KK K+EA+ E K G + +K+ +LQ +V+
Sbjct: 901 AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940
Query: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
KD L +L + + + ET +KL + QL EE EAK R
Sbjct: 941 --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985
Query: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1424
+S L +++ +K L+ S + +EE R+++E E L EE + E +R
Sbjct: 986 LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044
Query: 1425 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
+ Q+ ++ ++ + +QL +L ++ ++ LL E + +Y D ++
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104
Query: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1538
+ ++ + E E AEMED+ S ++ + L+ S L+
Sbjct: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159
Query: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
++ E++ + + ++DEL E+ LR + EE+R Q++
Sbjct: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198
Query: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1656
ELE E +R + KKL+ +L +L L SA + R L Q+
Sbjct: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254
Query: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
EL D R I + ++K+A + D + + E +K D K E+A+
Sbjct: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311
Query: 1717 LAS--SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA-MSDRVRKATQQAEQLSNEL 1773
+ +AL + + + + E L++ +E+ + + R +AE L E+
Sbjct: 1312 YIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEI 1371
Query: 1774 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1833
+ ++ + +QQL QN +L E +++ + I L + L EQ+E++
Sbjct: 1372 ----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQ 1422
Query: 1834 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEE 1891
+ + K LK KK+ E+ + + + E N + K + LE +E
Sbjct: 1423 DKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKE 1482
Query: 1892 ESQRINAN 1899
+ Q++ N
Sbjct: 1483 DEQKLVKN 1490
Score = 74.7 bits (182), Expect = 8e-13
Identities = 122/587 (20%), Positives = 246/587 (41%), Gaps = 61/587 (10%)
Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1252
M ++ + ++ +E++K+ ++ ++ ++++N D + L +
Sbjct: 900 MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959
Query: 1253 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
+ +KL + ++ LQ + + A L +++ KL+ ++E E A + ++
Sbjct: 960 ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019
Query: 1310 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1359
L S L++ LL++E ++ LN T ++L EE L+ L++E
Sbjct: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078
Query: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1416
QNL S L + D K+++ V + G KR + +Y E A D
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135
Query: 1417 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
+T+ ++++ D+ + L Q+++ ++KQ D+L +E+ + A E +R +
Sbjct: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195
Query: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
E E ++L E + K EL K L + V++
Sbjct: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA------------PGAP 1243
Query: 1536 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1595
A ME++ + EEL +++ E LR ++ Q + +Q +D++N +
Sbjct: 1244 AYRVLMEQLTSVSEEL--DVRKEEVLILRSQLVSQ------KEAIQPKDDKNTMTDSTI- 1294
Query: 1596 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQL-RKLQAQ 1653
L E +++D+ + K+ D EL D + E +KQ R L++Q
Sbjct: 1295 --LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ 1352
Query: 1654 MKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE- 1711
++ +R E +A A R EI + +EN ++ + L ++L AR +A L+ E
Sbjct: 1353 LQSQKRSHENEAEALRGEIQSLKEENNRQQQ-------LLAQNLQLPPEARIEASLQHEI 1405
Query: 1712 -ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE-EQGNMEAMS 1756
L E + R+L+ ++ +++ E E G ME +S
Sbjct: 1406 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENIS 1452
Score = 68.9 bits (167), Expect = 5e-11
Identities = 96/464 (20%), Positives = 191/464 (41%), Gaps = 56/464 (12%)
Query: 850 QEEEMQAKEDELQKTKER---QQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELYAE 905
QEE + ++D Q E+ ++ A+ +E EQ S L EE LL+++ +A + +
Sbjct: 989 QEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQ 1048
Query: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL------ 959
A+EM + K L E ++E L +E R Q L E ++ ++ DL+E++
Sbjct: 1049 AKEMTETMEKK---LVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105
Query: 960 -----EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
+ ++ + E + + ++I ++ED ++ + K L ++ T
Sbjct: 1106 PKPGHKRTDSTHSSNESEYIFS-SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164
Query: 1015 LAEEEE--------KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1066
L +E++ K + + + K K E L+ E RQELE +KL+ + ++
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224
Query: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-AQKNNALKKIRELEGHISDLQE 1125
+ +++ A E+ A L L + +E+ +K L +L +Q
Sbjct: 1225 LRKALSEKSAP--EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282
Query: 1126 DLDSERAARN----KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1181
D + + ++ +D GE +A E S EL + E+ ++ +
Sbjct: 1283 KDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELN--EDGELWLVYE 1340
Query: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK--------------------RAKAN 1221
L + R E+Q+Q ++ H E L +++ K R +A+
Sbjct: 1341 GLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1400
Query: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
L L EN DL +L + ++++ + K ++ EL+
Sbjct: 1401 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
Score = 68.2 bits (165), Expect = 8e-11
Identities = 87/393 (22%), Positives = 168/393 (42%), Gaps = 48/393 (12%)
Query: 1590 KRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRK 1649
+R +R+L + + E + + L +E + L+ + D K + +++L
Sbjct: 897 RRMMAKRELKKLKIEARSVERYKKLHIG----MENKIMQLQRKVDEQNKDYKCLVEKLTN 952
Query: 1650 LQ----AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK- 1704
L+ ++ + + +LE + S +E AK + SL+ ++ +L++DL +K
Sbjct: 953 LEGIYNSETEKLRSDLERLQLSEEE----AKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
Query: 1705 ---QADLEKEELAEELASSLSGRNAL-QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
AD K+E E+L S+L N L + EK L RI Q +E+ E ME +
Sbjct: 1009 IEEHADRYKQE-TEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------K 1058
Query: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA-- 1818
K ++ +QL +L ER Q + +LE + +L+ ++ M K K T +
Sbjct: 1059 KLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS 1118
Query: 1819 -------LEAKIAQLEE---QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY 1868
++IA++E+ + E+ + +K SL K L++ + ++E E+++ +
Sbjct: 1119 SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK---LQKRVTELEQEKQVMQDE 1175
Query: 1869 KEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
++ E+ Q+ R + EE Q A + E N+ + E+N L+ L
Sbjct: 1176 LDRKEE------QVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKAL 1229
Query: 1929 RRGNETSFVPSRRSGGRRVIENADGSEEETDTR 1961
+ R ++E EE D R
Sbjct: 1230 SEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVR 1262
Score = 59.3 bits (142), Expect = 4e-08
Identities = 91/498 (18%), Positives = 193/498 (38%), Gaps = 76/498 (15%)
Query: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
E + + EAR E + ++ + +++ NK K +E L + + +
Sbjct: 904 ELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEK 963
Query: 1530 LEKSKRALETQMEEMKT----------QLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
L L+ EE K ++ +L +L+ T K +E + K + E+
Sbjct: 964 LRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023
Query: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
+ E+N +++ + H + ++ + +KKL + K LEL +
Sbjct: 1024 VSNLKEENTLLKQEKEALNHRIVQQAKE------MTETMEKKLVEETKQLELDLNDERLR 1077
Query: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
+ + + +L+ + D + E+ + K K+ S + E + ++
Sbjct: 1078 YQNLLNEFSRLEERYDDLKEEMT-------LMVHVPKPGHKRTDSTHSS--NESEYIFSS 1128
Query: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
E A + + E E L L +L+ R+ +LE+E + Q ++ ++V
Sbjct: 1129 EIAEMEDIPSRTEEPSEKKVPLDMSLFL-----KLQKRVTELEQEKQVMQDELDRKEEQV 1183
Query: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA- 1818
++ + E+ E + RQ+LE +NK+L+++L+E+ A+ K + A
Sbjct: 1184 LRSKAKEEERPQIRGAE---LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAP 1240
Query: 1819 -------LEAKIAQLEEQVEQEARE-------KQAATKSLKQKDKK--LKEILLQVEDER 1862
L ++ + E+++ E + ++++ KD K + + + +ED +
Sbjct: 1241 GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ 1300
Query: 1863 KMAEQ--------------------YKEQAEKGN-----ARVKQLKRQLEEAEEESQRIN 1897
KM ++ Y E E G +KQ R LE + +R +
Sbjct: 1301 KMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSH 1360
Query: 1898 ANRRK-LQRELDEATESN 1914
N + L+ E+ E N
Sbjct: 1361 ENEAEALRGEIQSLKEEN 1378
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 34/173 (19%)
Query: 846 QVTRQEEEMQAKED------------ELQKTKERQQKAE-------------------NE 874
Q+ Q+E +Q K+D ++QK K++ + A+ NE
Sbjct: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331
Query: 875 LKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMRVRLAAKKQE--LEEILHEMEARL 931
EL + L + LL+ QLQ++ + EAE +R + + K+E ++ L +L
Sbjct: 1332 DGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQL 1391
Query: 932 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
E LQ E ++ + LDL EQLE+++ +KL+ + KI +LE
Sbjct: 1392 PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 513 bits (1320), Expect = e-145
Identities = 342/1013 (33%), Positives = 559/1013 (55%), Gaps = 61/1013 (6%)
Query: 36 VWVPSEKQGFEAASIKEEKGDEVVVELVENG-----KKVTVGKDDIQKMNPPKFSKVEDM 90
VW+ Q F + +G +VV + G K+ T+ + M+P V+DM
Sbjct: 11 VWLRENGQHFPSTVNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDM 68
Query: 91 AELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHE 149
A LT L+ S+++NL +RY IYTY G VNPY+ + +Y ++ Y + E
Sbjct: 69 ASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGE 128
Query: 150 MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
+PPHI+AIA+ YR + + ++Q IL +GESGAGKTE+TK ++++L+V++
Sbjct: 129 LPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKE 188
Query: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
T +E+ +L+++PI+EAFGNAKTV N+NSSRFGKF+++N G I G I YLLEK+
Sbjct: 189 KTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKN 248
Query: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMFQE 328
R +RQ ER +HIFY ++AG + + R + L NY +L+ +G V D E F+E
Sbjct: 249 RVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISDQESFRE 308
Query: 329 TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388
+ AM +M FS+EE + ++++ +L LGNI F A + TA + L+G++
Sbjct: 309 VITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELLGLD 365
Query: 389 VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448
T T ++ + + + + +QA + ++LA A Y F W++ ++N +
Sbjct: 366 PTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRI--KG 423
Query: 449 RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508
+ +GILDI GFE FEVN FEQ INY NEKLQ+ FN +F LEQ EY REG+ W
Sbjct: 424 NEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWED 483
Query: 509 IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ 568
ID+ +D C++LIE+ G+LAL++EE FP+ATD + +EKL ++ ++ + KP+
Sbjct: 484 IDW-IDNGECLDLIEK---KLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRV 539
Query: 569 LKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
+ F + HYAG+V Y+ L KN D D++ +LL S F+ DL++ V
Sbjct: 540 AVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVS----- 592
Query: 629 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
++ + +L SK ++ TV +K+ L LM TL ++ P FVRCI PN +K
Sbjct: 593 ---SRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646
Query: 689 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN-AIPKGFMDGKQAC 747
+ D +VL QLR +G+LE +RI + G+ R FQ+F +RY++L N A+P+ D + C
Sbjct: 647 QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE---DVRGKC 703
Query: 748 ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
+++ + + +++G++K+F R + LE+ R+ +++ M +A G+LARK +
Sbjct: 704 TSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYR 763
Query: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
K L + +IQ+N A+L R R K + +Q A+ Q E+
Sbjct: 764 K---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK 815
Query: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
+++ E + +E E+K + EE+ +E+ + E EL A+ EE K+QELE +
Sbjct: 816 REQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEE----TRKQQELEAL---Q 866
Query: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
+++ E E R + Q E K++ +++L LE+++E+ + R K Q E EA ++KL++
Sbjct: 867 KSQKEAELTRELEKQKENKQV-EEILRLEKEIEDLQ--RMKEQQELSLTEASLQKLQER- 922
Query: 988 LVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1039
D + +L +E + +E + L N E +E +N+ + + SEL
Sbjct: 923 --RDQELRRLEEEACRAAQEFLESL--NFDEIDECVRNIERSLSVGSEFSSEL 971
Score = 47.8 bits (112), Expect = 1e-04
Identities = 49/195 (25%), Positives = 88/195 (45%), Gaps = 21/195 (10%)
Query: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
R++ RQL + E E+++KQ KKK E + ++ E RE +LR Q
Sbjct: 805 RRVYRQLLAEKREQEEKKKQEE---EEKKKREEEERERE---------RERREAELRAQQ 852
Query: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
+ Q+ELE + S+ E T + ++K ++++L++++ +R ++Q +L
Sbjct: 853 EEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL--- 909
Query: 1712 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR---KATQQAEQ 1768
L E L R E RRLE + +E E N + + + VR ++ +
Sbjct: 910 SLTEASLQKLQERR--DQELRRLEEEACRAAQEFLESL-NFDEIDECVRNIERSLSVGSE 966
Query: 1769 LSNELATERSTAQKN 1783
S+ELA + N
Sbjct: 967 FSSELAESACEEKPN 981
Score = 46.2 bits (108), Expect = 3e-04
Identities = 52/237 (21%), Positives = 101/237 (42%), Gaps = 19/237 (8%)
Query: 874 ELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR--- 930
+L + QL + K L+E L+ + E E E + + L + + +
Sbjct: 708 QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767
Query: 931 ---LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL--EKVTAEAKIKKLED 985
+ ++ R L+ + + + ++QL + A R QL EK E K K+ E+
Sbjct: 768 CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE 827
Query: 986 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
E +++ + +ER R ++L EE K + L L+ + E+ +K
Sbjct: 828 EKKKREEEERERERER-----REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
Query: 1046 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
E K +E+ +L++++E D E Q +++ + L K +E L RL++E
Sbjct: 883 ENKQVEEILRLEKEIE-DLQRMKE-----QQELSLTEASLQKLQERRDQELRRLEEE 933
Score = 45.4 bits (106), Expect = 5e-04
Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 45/231 (19%)
Query: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
QL + E +KQ + EK++ EE + E+ R EA + +EE +Q
Sbjct: 810 QLLAEKREQEEKKKQEEEEKKKREEE---------ERERERERREAELRAQQEEETRKQQ 860
Query: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
+EA+ + +Q+ +L+ EL ++ Q E R LE++ ++L+ + E
Sbjct: 861 ELEAL-----QKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQE----- 908
Query: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQKD-KKLKEILLQVEDERKM 1864
++ EA + +L+E+ +QE R + AA + L+ + ++ E + +E +
Sbjct: 909 -----LSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSV 963
Query: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
++ + E A EE N ++ + E+DE E+++
Sbjct: 964 GSEFSSEL-------------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/193 (21%), Positives = 87/193 (45%), Gaps = 10/193 (5%)
Query: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
L+K Q++L + ++ L E++++K + ++K + ER+R EAE
Sbjct: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847
Query: 1478 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
R ++ + + LE ++++E E T ++ K + V + K + +L++ K
Sbjct: 848 LRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQ 907
Query: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
E + E Q +LQ D +LR + +A + E ++ +E R ++R
Sbjct: 908 ELSLTEASLQ------KLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
Query: 1598 L---HEYETELED 1607
L E+ +EL +
Sbjct: 961 LSVGSEFSSELAE 973
Score = 41.2 bits (95), Expect = 0.010
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKR 1058
R+LL E+ EEEEK K + + + E E E+R ++EE++R QELE L++
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEE-ERERERERREAELRAQQEEETRKQQELEALQK 867
Query: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA-ALARLDDEI--AQKNNALKKIRE 1115
+ AEL +L K++E Q + RL+ EI Q+ +++
Sbjct: 868 ----------------SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSL 911
Query: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151
E + LQE D E R E+ R E LE+L
Sbjct: 912 TEASLQKLQERRDQE--LRRLEEEACRAAQEFLESL 945
Score = 40.4 bits (93), Expect = 0.017
Identities = 29/116 (25%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
L A+ + EE+ +QE EK+ + ++++++ +E L+ + E + +Q + +A + + +
Sbjct: 811 LLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQK 870
Query: 1879 VKQLKRQLEEAEEESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
+L R+LE+ +E Q R K +L E E E + K + RR E
Sbjct: 871 EAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 15/154 (9%)
Query: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
E E+ +K+ Q+E E ++ EE+ E+ + R + EL + ++Q + L+
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866
Query: 1448 KKQRKFDQLLAEEKNISSKYADERDRAEAE----AREKETKALSLARALEEALEAK--EE 1501
K Q++ + EK +K +E R E E R KE + LSL A + L+ + +E
Sbjct: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
Query: 1502 LER-TNKMLKAEMEDLVS-SKDDVGKNVHELEKS 1533
L R + +A E L S + D++ + V +E+S
Sbjct: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
Score = 39.7 bits (91), Expect = 0.029
Identities = 88/372 (23%), Positives = 149/372 (40%), Gaps = 54/372 (14%)
Query: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
+R L NLA E+ T L +++ SE ++ K +KL+++ E + S
Sbjct: 684 KRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVS 743
Query: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD--- 1122
A + + L K+ ++ + I QKN +R H+
Sbjct: 744 H-----AAMVIRAHVLGFLARKQYRKVLYCVV-----IIQKNYRAFLLRRRFLHLKKAAI 793
Query: 1123 -LQEDLDSERAAR-------NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Q+ L + A R K E++++ EE E K E ++E +RE+
Sbjct: 794 VFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKRE----------EEERERERER 843
Query: 1175 EVTVLKKALDEETR-SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1233
L+ +EETR E + + QK A ELT +LE+ K +NKQ +E
Sbjct: 844 REAELRAQQEEETRKQQELEALQKSQKEA----ELTRELEKQK-------ENKQV--EEI 890
Query: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
L E+ L + K++ E EA +Q+LQ + D E R E + Q +ES+
Sbjct: 891 LRLEKEIEDLQRMKEQQE--LSLTEASLQKLQER-RDQELRRLE-EEACRAAQEFLESLN 946
Query: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
+E + + + SLS + + EL + +K N + EEE + + D
Sbjct: 947 --FDEIDECVRNIER---SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
Query: 1354 EEMEAKQNLERH 1365
+ + N H
Sbjct: 1002 DAFKDSPNPSEH 1013
Score = 38.5 bits (88), Expect = 0.066
Identities = 56/219 (25%), Positives = 100/219 (45%), Gaps = 34/219 (15%)
Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
++LL E+ Q+ K +Q EEE+ EE E ++ ER + L Q + +K
Sbjct: 809 RQLLAEKREQE----EKKKQEEEEKKKR-----EEEERERERERREAELRAQQEEETRKQ 859
Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Q+ +EAL++ QKE E LT++ E++ +K + RL++E++DL + Q+
Sbjct: 860 QE----LEALQKS----QKEAE-LTRELEKQKE--NKQVEEILRLEKEIEDL-QRMKEQQ 907
Query: 1441 QL---VSNLEKKQRKFDQLL---------AEEKNISSKYADERDRAEAEAREKETKALSL 1488
+L ++L+K Q + DQ L A ++ + S DE D +
Sbjct: 908 ELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967
Query: 1489 ARAL-EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
+ L E A E K + + E+++ + DD K+
Sbjct: 968 SSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKD 1006
Score = 37.7 bits (86), Expect = 0.11
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Query: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER-HISTLNIQLSDS 1376
Q+ ++ +EE ++K + R+ E L+ Q +EE +Q LE S +L+
Sbjct: 818 QEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRE 877
Query: 1377 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK--LEKTKNRLQQEL 1429
+K ++ E L R +KEIE+L + E++ + + L+K + R QEL
Sbjct: 878 LEKQKENKQVEEIL-----RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 497 bits (1280), Expect = e-140
Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)
Query: 59 VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
VV+L ++G+ V +D I+ M+P VEDM L LNEA +L NL
Sbjct: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
Query: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
RY LIYTY+G V VNPY+ L IYS + + Y KK EMPPHI+AIAD Y +M
Sbjct: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
Query: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L+A PILE
Sbjct: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197
Query: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
AFGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER +H+FY
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257
Query: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
M+ G E + L L ++Y +L+ G + D + + AM ++ F++ E
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317
Query: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
I K+++++L LGN+ ++ N D + + + L+ +N D S LT R +
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376
Query: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
R + V ++EQA +A K Y RLF WI+ ++N A+ K Q +G+L
Sbjct: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436
Query: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
DI GFE F VNSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F D Q
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495
Query: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
+++I N P +++L+DEE FPK TD + + KL ++ + + PK +T+F I
Sbjct: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552
Query: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
H+AG V Y +L KN D L+ ++ L+++S +KF+ ++ ++
Sbjct: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596
Query: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
+ ++T+K T+ +K L LM TL P FVRCI PN K+ D L + Q
Sbjct: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655
Query: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
LR +G++E IRI R G+P R F EF +RY +L P D + C M +A+
Sbjct: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715
Query: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
+ ++IG++KIF + LE ERD ITD ++ Q + RG+ R F K + T
Sbjct: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772
Query: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
+IQR+ + +N+ RL F +++ L + + ++ + Q+ + Q + L
Sbjct: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829
Query: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
+H + LT + L ++L+AE EAE+MR+ E E++ E
Sbjct: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883
Query: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
M A+ +EE AERK ++AQ D E +L+E+EAAR+K +L
Sbjct: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925
Score = 52.0 bits (123), Expect = 6e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
I+ FQA CR YL RKAF R + ++ R A + +LR WRL + L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
Query: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
+ +EM +AKE+ +K +ER + E E E K + K L EQ++
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Score = 35.4 bits (80), Expect = 0.56
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)
Query: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
++RL +EEK R+E+ K K E + E++A L + AE ++ + A++++EL +
Sbjct: 871 KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929
Query: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
R E ++ + K+ G L + E+ +R++ EE L+A L
Sbjct: 930 ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989
Query: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
E E+ L S + A Q T ++ L + H+ + ++
Sbjct: 990 DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048
Query: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
K+ A+ + +E++ + L K E + GE ++ GQ K V
Sbjct: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108
Query: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
HK KK +E+ + DGE
Sbjct: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 497 bits (1280), Expect = e-140
Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)
Query: 59 VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
VV+L ++G+ V +D I+ M+P VEDM L LNEA +L NL
Sbjct: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
Query: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
RY LIYTY+G V VNPY+ L IYS + + Y KK EMPPHI+AIAD Y +M
Sbjct: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
Query: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L+A PILE
Sbjct: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197
Query: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
AFGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER +H+FY
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257
Query: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
M+ G E + L L ++Y +L+ G + D + + AM ++ F++ E
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317
Query: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
I K+++++L LGN+ ++ N D + + + L+ +N D S LT R +
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376
Query: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
R + V ++EQA +A K Y RLF WI+ ++N A+ K Q +G+L
Sbjct: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436
Query: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
DI GFE F VNSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F D Q
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495
Query: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
+++I N P +++L+DEE FPK TD + + KL ++ + + PK +T+F I
Sbjct: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552
Query: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
H+AG V Y +L KN D L+ ++ L+++S +KF+ ++ ++
Sbjct: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596
Query: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
+ ++T+K T+ +K L LM TL P FVRCI PN K+ D L + Q
Sbjct: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655
Query: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
LR +G++E IRI R G+P R F EF +RY +L P D + C M +A+
Sbjct: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715
Query: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
+ ++IG++KIF + LE ERD ITD ++ Q + RG+ R F K + T
Sbjct: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772
Query: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
+IQR+ + +N+ RL F +++ L + + ++ + Q+ + Q + L
Sbjct: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829
Query: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
+H + LT + L ++L+AE EAE+MR+ E E++ E
Sbjct: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883
Query: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
M A+ +EE AERK ++AQ D E +L+E+EAAR+K +L
Sbjct: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925
Score = 52.0 bits (123), Expect = 6e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
I+ FQA CR YL RKAF R + ++ R A + +LR WRL + L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
Query: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
+ +EM +AKE+ +K +ER + E E E K + K L EQ++
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Score = 35.4 bits (80), Expect = 0.56
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)
Query: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
++RL +EEK R+E+ K K E + E++A L + AE ++ + A++++EL +
Sbjct: 871 KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929
Query: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
R E ++ + K+ G L + E+ +R++ EE L+A L
Sbjct: 930 ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989
Query: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
E E+ L S + A Q T ++ L + H+ + ++
Sbjct: 990 DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048
Query: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
K+ A+ + +E++ + L K E + GE ++ GQ K V
Sbjct: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108
Query: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
HK KK +E+ + DGE
Sbjct: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 497 bits (1280), Expect = e-140
Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)
Query: 59 VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
VV+L ++G+ V +D I+ M+P VEDM L LNEA +L NL
Sbjct: 27 VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86
Query: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
RY LIYTY+G V VNPY+ L IYS + + Y KK EMPPHI+AIAD Y +M
Sbjct: 87 IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146
Query: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
++ DQ + +GESGAGKTE+TK ++Q+LA ++ H +E+Q+L+A PILE
Sbjct: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197
Query: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
AFGNAKT++NDNSSRFGK+I I+F+ G I GA IE YLLEKSR RQA DER +H+FY
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257
Query: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
M+ G E + L L ++Y +L+ G + D + + AM ++ F++ E
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317
Query: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
I K+++++L LGN+ ++ N D + + + L+ +N D S LT R +
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376
Query: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
R + V ++EQA +A K Y RLF WI+ ++N A+ K Q +G+L
Sbjct: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436
Query: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
DI GFE F VNSFEQLCIN+ NE LQQ F +F LEQEEY E I+W I+F D Q
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495
Query: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
+++I N P +++L+DEE FPK TD + + KL ++ + + PK +T+F I
Sbjct: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552
Query: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
H+AG V Y +L KN D L+ ++ L+++S +KF+ ++ ++
Sbjct: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596
Query: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
+ ++T+K T+ +K L LM TL P FVRCI PN K+ D L + Q
Sbjct: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655
Query: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
LR +G++E IRI R G+P R F EF +RY +L P D + C M +A+
Sbjct: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715
Query: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
+ ++IG++KIF + LE ERD ITD ++ Q + RG+ R F K + T
Sbjct: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772
Query: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
+IQR+ + +N+ RL F +++ L + + ++ + Q+ + Q + L
Sbjct: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829
Query: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
+H + LT + L ++L+AE EAE+MR+ E E++ E
Sbjct: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883
Query: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
M A+ +EE AERK ++AQ D E +L+E+EAAR+K +L
Sbjct: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925
Score = 52.0 bits (123), Expect = 6e-06
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
I+ FQA CR YL RKAF R + ++ R A + +LR WRL + L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876
Query: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
+ +EM +AKE+ +K +ER + E E E K + K L EQ++
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930
Score = 35.4 bits (80), Expect = 0.56
Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)
Query: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
++RL +EEK R+E+ K K E + E++A L + AE ++ + A++++EL +
Sbjct: 871 KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929
Query: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
R E ++ + K+ G L + E+ +R++ EE L+A L
Sbjct: 930 ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989
Query: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
E E+ L S + A Q T ++ L + H+ + ++
Sbjct: 990 DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048
Query: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
K+ A+ + +E++ + L K E + GE ++ GQ K V
Sbjct: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108
Query: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
HK KK +E+ + DGE
Sbjct: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,886,486
Number of Sequences: 37866
Number of extensions: 3096064
Number of successful extensions: 100371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1151
Number of HSP's successfully gapped in prelim test: 1699
Number of HSP's that attempted gapping in prelim test: 16292
Number of HSP's gapped (non-prelim): 25444
length of query: 1972
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1855
effective length of database: 13,817,196
effective search space: 25630898580
effective search space used: 25630898580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.