Search of human proteins with 13124875

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A
[Homo sapiens]
         (1938 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...  3728   0.0  
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...  3721   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...  3708   0.0  
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...  3701   0.0  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]  2961   0.0  
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]   2940   0.0  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]         2459   0.0  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]         2452   0.0  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]         2435   0.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...  1445   0.0  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...  1435   0.0  
gi|156104908 myosin heavy chain 6 [Homo sapiens]                     1432   0.0  
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...  1424   0.0  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...  1424   0.0  
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1423   0.0  
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...  1423   0.0  
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...  1420   0.0  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...  1388   0.0  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...  1387   0.0  
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]             1241   0.0  
gi|153945715 myosin VC [Homo sapiens]                                 607   e-173
gi|28416946 myosin 18A isoform a [Homo sapiens]                       600   e-171
gi|42794779 myosin 18A isoform b [Homo sapiens]                       598   e-170
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       598   e-170
gi|122937345 myosin VB [Homo sapiens]                                 596   e-170
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       596   e-170
gi|154354979 myosin X [Homo sapiens]                                  513   e-145
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     497   e-140
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     497   e-140
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     497   e-140

>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 3728 bits (9667), Expect = 0.0
 Identities = 1938/1938 (100%), Positives = 1938/1938 (100%)

Query: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
            MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
            ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
            FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
            GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240

Query: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
            RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL
Sbjct: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300

Query: 301  LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
            LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV
Sbjct: 301  LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360

Query: 361  FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
            FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA
Sbjct: 361  FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420

Query: 421  VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
            VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN
Sbjct: 421  VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480

Query: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
            EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW
Sbjct: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540

Query: 541  FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
            FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN
Sbjct: 541  FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600

Query: 601  DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
            DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ
Sbjct: 601  DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660

Query: 661  LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
            LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661  LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720

Query: 721  FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
            FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE
Sbjct: 721  FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780

Query: 781  ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
            ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK
Sbjct: 781  ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840

Query: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
            VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET
Sbjct: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900

Query: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
            ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE
Sbjct: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960

Query: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
            EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE
Sbjct: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020

Query: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
            KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080

Query: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
            LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140

Query: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
            KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200

Query: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
            HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260

Query: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
            VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320

Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
            QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380

Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
            QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440

Query: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
            QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500

Query: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
            ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560

Query: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
            AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620

Query: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
            KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680

Query: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
            KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740

Query: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
            LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800

Query: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
            LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860

Query: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
            ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920

Query: 1921 VNALKSKLRGPPPQETSQ 1938
            VNALKSKLRGPPPQETSQ
Sbjct: 1921 VNALKSKLRGPPPQETSQ 1938


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 3721 bits (9649), Expect = 0.0
 Identities = 1938/1945 (99%), Positives = 1938/1945 (99%), Gaps = 7/1945 (0%)

Query: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
            MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
            ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
            FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSIT-------GELEKQLLQANPILEAFGNAKT 233
            GAGKTENTKKVIQYLAVVASSHKGKKDTSIT       GELEKQLLQANPILEAFGNAKT
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT 240

Query: 234  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 293
            VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE
Sbjct: 241  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 300

Query: 294  KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 353
            KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV
Sbjct: 301  KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 360

Query: 354  LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 413
            LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT
Sbjct: 361  LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 420

Query: 414  KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 473
            KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ
Sbjct: 421  KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 480

Query: 474  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 533
            LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA
Sbjct: 481  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 540

Query: 534  LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 593
            LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT
Sbjct: 541  LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 600

Query: 594  KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 653
            KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV
Sbjct: 601  KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 660

Query: 654  GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 713
            GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ
Sbjct: 661  GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 720

Query: 714  GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 773
            GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG
Sbjct: 721  GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 780

Query: 774  VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 833
            VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ
Sbjct: 781  VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 840

Query: 834  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 893
            WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ
Sbjct: 841  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900

Query: 894  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
            EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML
Sbjct: 901  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 954  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
            DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
            NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080

Query: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
            LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140

Query: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
            RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200

Query: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1253
            VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260

Query: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
            KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320

Query: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
            SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380

Query: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
            SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
            VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500

Query: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
            EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560

Query: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
            ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620

Query: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
            LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680

Query: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1733
            TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1740

Query: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
            LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800

Query: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
            NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860

Query: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
            ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920

Query: 1914 NEAMGREVNALKSKLRGPPPQETSQ 1938
            NEAMGREVNALKSKLRGPPPQETSQ
Sbjct: 1921 NEAMGREVNALKSKLRGPPPQETSQ 1945


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 3708 bits (9616), Expect = 0.0
 Identities = 1929/1929 (100%), Positives = 1929/1929 (100%)

Query: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
            MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
            ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
            FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
            GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240

Query: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
            RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL
Sbjct: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300

Query: 301  LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
            LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV
Sbjct: 301  LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360

Query: 361  FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
            FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA
Sbjct: 361  FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420

Query: 421  VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
            VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN
Sbjct: 421  VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480

Query: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
            EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW
Sbjct: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540

Query: 541  FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
            FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN
Sbjct: 541  FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600

Query: 601  DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
            DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ
Sbjct: 601  DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660

Query: 661  LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
            LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661  LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720

Query: 721  FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
            FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE
Sbjct: 721  FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780

Query: 781  ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
            ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK
Sbjct: 781  ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840

Query: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
            VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET
Sbjct: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900

Query: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
            ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE
Sbjct: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960

Query: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
            EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE
Sbjct: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020

Query: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
            KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE
Sbjct: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080

Query: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
            LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ
Sbjct: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140

Query: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
            KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200

Query: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
            HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ
Sbjct: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260

Query: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
            VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT
Sbjct: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320

Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
            QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380

Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
            QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440

Query: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
            QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500

Query: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
            ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560

Query: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
            AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK
Sbjct: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620

Query: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
            KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK
Sbjct: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680

Query: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
            KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ
Sbjct: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740

Query: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
            LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK
Sbjct: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800

Query: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
            LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860

Query: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
            ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920

Query: 1921 VNALKSKLR 1929
            VNALKSKLR
Sbjct: 1921 VNALKSKLR 1929



 Score =  163 bits (413), Expect = 1e-39
 Identities = 152/636 (23%), Positives = 279/636 (43%), Gaps = 98/636 (15%)

Query: 842  KPLLQVTRQEEEMQAKEDELQKTKERQQKAENEL-----------KELEQKHSQ----LT 886
            K +  +T+Q EE  A  D+L+KTK R Q+  ++L             LE+K  +    L 
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458

Query: 887  EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 946
            EEKN+  +         AEA E   +  +  + LEE L   EA+ EE E   + L+AE +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAK-EELERTNKMLKAEME 1514

Query: 947  KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1006
             +     D+ + + E E +++ L+ +    + ++++LEDE+   +D   +L    + L+ 
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1574

Query: 1007 RIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
            +   DL     + EEK + L +        + E E  L+ E K R      K+KLEGD  
Sbjct: 1575 QFERDLQARDEQNEEKRRQLQR-------QLHEYETELEDERKQRALAAAAKKKLEGDLK 1627

Query: 1066 DFHEQI-------ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
            D   Q         +   Q+ +L+ Q+   + EL+ A A  D+  A      KK + LE 
Sbjct: 1628 DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1687

Query: 1119 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1178
             +  LQEDL +   AR +A+ +K +L E       EL  +L                   
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAE-------ELASSLSG----------------- 1723

Query: 1179 LKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG 1238
             + AL +E R  EA++       AQ  EEL E+    +     + K  Q  E+    L+ 
Sbjct: 1724 -RNALQDEKRRLEARI-------AQLEEELEEEQGNMEAMSDRVRKATQQAEQ----LSN 1771

Query: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
            EL       Q+ E  +++LE Q +EL+SK              +H+++  V+S       
Sbjct: 1772 ELATERSTAQKNESARQQLERQNKELRSK--------------LHEMEGAVKS------- 1810

Query: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
                  K    +A+L +++   +E +++E R+K   +  L+Q +++   +  Q+++E + 
Sbjct: 1811 ------KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1864

Query: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
             +  +      N ++   K++L++     + +   +++ Q+E++  T+  E      + L
Sbjct: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924

Query: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454
             K+K R   E   +       R+++ N +  + + D
Sbjct: 1925 -KSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1959


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 3701 bits (9598), Expect = 0.0
 Identities = 1929/1936 (99%), Positives = 1929/1936 (99%), Gaps = 7/1936 (0%)

Query: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
            MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV
Sbjct: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60

Query: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
            ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL
Sbjct: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120

Query: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
            FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES
Sbjct: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSIT-------GELEKQLLQANPILEAFGNAKT 233
            GAGKTENTKKVIQYLAVVASSHKGKKDTSIT       GELEKQLLQANPILEAFGNAKT
Sbjct: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKT 240

Query: 234  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 293
            VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE
Sbjct: 241  VKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKE 300

Query: 294  KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 353
            KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV
Sbjct: 301  KMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSV 360

Query: 354  LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 413
            LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT
Sbjct: 361  LQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT 420

Query: 414  KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 473
            KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ
Sbjct: 421  KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQ 480

Query: 474  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 533
            LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA
Sbjct: 481  LCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLA 540

Query: 534  LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 593
            LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT
Sbjct: 541  LLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLT 600

Query: 594  KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 653
            KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV
Sbjct: 601  KNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTV 660

Query: 654  GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 713
            GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ
Sbjct: 661  GQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQ 720

Query: 714  GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 773
            GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG
Sbjct: 721  GFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTG 780

Query: 774  VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 833
            VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ
Sbjct: 781  VLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQ 840

Query: 834  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 893
            WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ
Sbjct: 841  WWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQ 900

Query: 894  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
            EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML
Sbjct: 901  EQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960

Query: 954  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1013
            DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT
Sbjct: 961  DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTT 1020

Query: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1073
            NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD 1080

Query: 1074 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
            LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA
Sbjct: 1081 LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140

Query: 1134 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1193
            RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQ 1200

Query: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1253
            VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK
Sbjct: 1201 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260

Query: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
            KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1320

Query: 1314 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1373
            SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL
Sbjct: 1321 SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQL 1380

Query: 1374 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
            SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV
Sbjct: 1381 SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLV 1440

Query: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
            VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500

Query: 1494 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1553
            EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED
Sbjct: 1501 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 1560

Query: 1554 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1613
            ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA
Sbjct: 1561 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 1620

Query: 1614 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1673
            LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA
Sbjct: 1621 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFA 1680

Query: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1733
            TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRR 1740

Query: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793
            LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800

Query: 1794 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1853
            NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE
Sbjct: 1801 NKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKE 1860

Query: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1913
            ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES 1920

Query: 1914 NEAMGREVNALKSKLR 1929
            NEAMGREVNALKSKLR
Sbjct: 1921 NEAMGREVNALKSKLR 1936



 Score =  163 bits (413), Expect = 1e-39
 Identities = 152/636 (23%), Positives = 279/636 (43%), Gaps = 98/636 (15%)

Query: 842  KPLLQVTRQEEEMQAKEDELQKTKERQQKAENEL-----------KELEQKHSQ----LT 886
            K +  +T+Q EE  A  D+L+KTK R Q+  ++L             LE+K  +    L 
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 887  EEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK 946
            EEKN+  +         AEA E   +  +  + LEE L   EA+ EE E   + L+AE +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEAL---EAK-EELERTNKMLKAEME 1521

Query: 947  KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEE 1006
             +     D+ + + E E +++ L+ +    + ++++LEDE+   +D   +L    + L+ 
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1581

Query: 1007 RIS-DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
            +   DL     + EEK + L +        + E E  L+ E K R      K+KLEGD  
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQR-------QLHEYETELEDERKQRALAAAAKKKLEGDLK 1634

Query: 1066 DFHEQI-------ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEG 1118
            D   Q         +   Q+ +L+ Q+   + EL+ A A  D+  A      KK + LE 
Sbjct: 1635 DLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1694

Query: 1119 HISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV 1178
             +  LQEDL +   AR +A+ +K +L E       EL  +L                   
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAE-------ELASSLSG----------------- 1730

Query: 1179 LKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG 1238
             + AL +E R  EA++       AQ  EEL E+    +     + K  Q  E+    L+ 
Sbjct: 1731 -RNALQDEKRRLEARI-------AQLEEELEEEQGNMEAMSDRVRKATQQAEQ----LSN 1778

Query: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
            EL       Q+ E  +++LE Q +EL+SK              +H+++  V+S       
Sbjct: 1779 ELATERSTAQKNESARQQLERQNKELRSK--------------LHEMEGAVKS------- 1817

Query: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
                  K    +A+L +++   +E +++E R+K   +  L+Q +++   +  Q+++E + 
Sbjct: 1818 ------KFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKM 1871

Query: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
             +  +      N ++   K++L++     + +   +++ Q+E++  T+  E      + L
Sbjct: 1872 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931

Query: 1419 EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454
             K+K R   E   +       R+++ N +  + + D
Sbjct: 1932 -KSKLRRGNETSFVPSRRSGGRRVIENADGSEEETD 1966


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 2961 bits (7677), Expect = 0.0
 Identities = 1489/1933 (77%), Positives = 1724/1933 (89%)

Query: 1    MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVV 60
            MAQ+  L D E++LFVD+  I +P  QADW AK+LVW+PSE+ GFEAASIKEE+GDEV+V
Sbjct: 1    MAQRTGLEDPERYLFVDRAVIYNPATQADWTAKKLVWIPSERHGFEAASIKEERGDEVMV 60

Query: 61   ELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGL 120
            EL ENGKK  V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL++RY+SGLIYTYSGL
Sbjct: 61   ELAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGL 120

Query: 121  FCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGES 180
            FCVV+NPYK+LPIYSE I++MY+GKKRHEMPPHIYAI+++AYR MLQDREDQSILCTGES
Sbjct: 121  FCVVINPYKNLPIYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGES 180

Query: 181  GAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSS 240
            GAGKTENTKKVIQYLA VASSHKG+KD +I GELE+QLLQANPILE+FGNAKTVKNDNSS
Sbjct: 181  GAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSS 240

Query: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLL 300
            RFGKFIRINFDVTGYIVGANIETYLLEKSRA+RQA+DERTFHIFY +++GA E ++SDLL
Sbjct: 241  RFGKFIRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLL 300

Query: 301  LEGFNNYTFLSNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIV 360
            LEGFNNY FLSNG++PIP  QD + FQET+EAM IMGFS EE LS+LKVVSSVLQ GNI 
Sbjct: 301  LEGFNNYRFLSNGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNIS 360

Query: 361  FKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFA 420
            FKKERNTDQASMP+NT AQK+CHL+G+NV +FTR+ILTPRIKVGRD VQKAQTKEQADFA
Sbjct: 361  FKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFA 420

Query: 421  VEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTN 480
            VEALAKATYERLFRW++ R+NKALD+T RQGASF+GILDIAGFEIFE+NSFEQLCINYTN
Sbjct: 421  VEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTN 480

Query: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECW 540
            EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCI+LIERP NPPGVLALLDEECW
Sbjct: 481  EKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECW 540

Query: 541  FPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLN 600
            FPKATDK+FVEKL  EQGSH KFQKP+QLKDK +F IIHYAGKVDY A  WL KNMDPLN
Sbjct: 541  FPKATDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLN 600

Query: 601  DNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQ 660
            DNV +LL+ SSD+FVA+LWKDVDRIVGLDQ+  MTE++  SA KTKKGMFRTVGQLYKE 
Sbjct: 601  DNVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKES 660

Query: 661  LGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720
            L KLM TLRNT PNFVRCIIPNHEKR+GKLD  LVL+QLRCNGVLEGIRICRQGFPNRIV
Sbjct: 661  LTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIV 720

Query: 721  FQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEE 780
            FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYRIGQSKIFFR GVLAHLEE
Sbjct: 721  FQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEE 780

Query: 781  ERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTK 840
            ERDLKITD+I+ FQA+CRGYLARKAFAK+QQQL+A+KV+QRNCAAYLKLR+WQWWR+FTK
Sbjct: 781  ERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTK 840

Query: 841  VKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
            VKPLLQVTRQEEE+QAK++EL K KE+Q K E EL+E+E+KH QL EEKN+L EQLQAET
Sbjct: 841  VKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAET 900

Query: 901  ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
            EL+AEAEEMR RLAAKKQELEEILH++E+R+EEEE+R Q LQ E+KKM   + DLEEQL+
Sbjct: 901  ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960

Query: 961  EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEE 1020
            EEE ARQKLQLEKVTAEAKIKK+E+EIL+++DQN+K  KE+KL+E+RI++ ++ LAEEEE
Sbjct: 961  EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020

Query: 1021 KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAE 1080
            KAKNL K++NK E MIS+LE RLKKEEK+RQELEK KRKL+G+ +D  +QIA+LQAQI E
Sbjct: 1021 KAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDE 1080

Query: 1081 LKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
            LK+QLAKKEEELQ ALAR DDE   KNNALK +REL+  I++LQED +SE+A+RNKAEKQ
Sbjct: 1081 LKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140

Query: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
            KRDL EELEALKTELEDTLD+TA QQELR KREQEV  LKKAL+EET++HEAQ+Q+MRQ+
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200

Query: 1201 HAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQ 1260
            HA A+EEL+EQLEQ KR KANL+KNKQ LE +N +LA E++VL Q K E EHK+KKL+AQ
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260

Query: 1261 VQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 1320
            VQEL +K S+G+R R EL +K  KLQNE+++V+ +L EAE K IK AKD ASL SQLQDT
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320

Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
            QELLQEETRQKLN+S+++RQLEEE+NSLQ+Q +EE EA++NLE+ +  L  QL+D+KKK+
Sbjct: 1321 QELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKV 1380

Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
             D   T+E+LEE KK+  K+ E L+Q+ EEKA AYDKLEKTKNRLQQELDDL VDLD+QR
Sbjct: 1381 DDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440

Query: 1441 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 1500
            Q+ SNLEKKQ+KFDQLLAEEK+IS++YA+ERDRAEAEAREKETKALSLARALEEALEAKE
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500

Query: 1501 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED 1560
            E ER NK L+A+MEDL+SSKDDVGKNVHELEKSKRALE Q+EEM+TQLEELEDELQATED
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATED 1560

Query: 1561 AKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
            AKLRLEVNMQA+K QFERDLQ RDEQNEEK+R L +Q+ E E ELEDERKQRALA A+KK
Sbjct: 1561 AKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKK 1620

Query: 1621 KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEK 1680
            K+E DLKDLE Q ++A K R+E IKQLRKLQAQMKD+QRELE+ARASRDEIFA +KE+EK
Sbjct: 1621 KMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEK 1680

Query: 1681 KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQ 1740
            K KSLEA+++QLQE+LA++ERAR+ A+ E++ELA+E+ +S SG++AL DEKRRLEARIAQ
Sbjct: 1681 KLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ 1740

Query: 1741 LEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
            LEEELEEEQ NME ++DR RK T Q + L+ ELA ERS AQK+++ARQQLERQNKEL++K
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAK 1800

Query: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
            L E+EGAVKSKFK+TI+ALEAKI QLEEQ+EQEA+E+ AA K +++ +KKLKEI +QVED
Sbjct: 1801 LQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVED 1860

Query: 1861 ERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGRE 1920
            ER+ A+QYKEQ EK NAR+KQLKRQLEEAEEE+ R NA+RRKLQRELD+ATE+NE + RE
Sbjct: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSRE 1920

Query: 1921 VNALKSKLRGPPP 1933
            V+ LK++LR   P
Sbjct: 1921 VSTLKNRLRRGGP 1933


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 2940 bits (7621), Expect = 0.0
 Identities = 1479/1920 (77%), Positives = 1716/1920 (89%), Gaps = 5/1920 (0%)

Query: 11   EKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVT 70
            +K+L+VDKNFIN+P+AQADWAAK+LVWVPS+K GFE AS+KEE G+E +VELVENGKKV 
Sbjct: 7    DKYLYVDKNFINNPLAQADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVK 66

Query: 71   VGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKH 130
            V KDDIQKMNPPKFSKVEDMAELTCLNEASVLHNL+ERY+SGLIYTYSGLFCVV+NPYK+
Sbjct: 67   VNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKN 126

Query: 131  LPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKK 190
            LPIYSE+IV+MYKGKKRHEMPPHIYAI DTAYRSM+QDREDQSILCTGESGAGKTENTKK
Sbjct: 127  LPIYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKK 186

Query: 191  VIQYLAVVASSHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 250
            VIQYLA VASSHK KKD    GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF
Sbjct: 187  VIQYLAYVASSHKSKKDQ---GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 243

Query: 251  DVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFL 310
            DV GYIVGANIETYLLEKSRAIRQA++ERTFHIFYY+++GA E +++DLLLE +N Y FL
Sbjct: 244  DVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFL 303

Query: 311  SNGFVPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQA 370
            SNG V IP  QD +MFQET+EAM IMG  EEEQ+ +L+V+S VLQLGNIVFKKERNTDQA
Sbjct: 304  SNGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQA 363

Query: 371  SMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYE 430
            SMPDNTAAQKV HL+GINVTDFTR ILTPRIKVGRD VQKAQTKEQADFA+EALAKATYE
Sbjct: 364  SMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYE 423

Query: 431  RLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHT 490
            R+FRW++ R+NKALDKT RQGASF+GILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHT
Sbjct: 424  RMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHT 483

Query: 491  MFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFV 550
            MFILEQEEYQREGIEWNFIDFGLDLQPCI+LIE+P  PPG+LALLDEECWFPKATDKSFV
Sbjct: 484  MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFV 543

Query: 551  EKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNAS 610
            EK+  EQG+HPKFQKPKQLKDK +F IIHYAGKVDY A  WL KNMDPLNDN+ +LL+ S
Sbjct: 544  EKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQS 603

Query: 611  SDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRN 670
            SDKFV++LWKDVDRI+GLDQ+A M+E++LP A KT+KGMFRTVGQLYKEQL KLM TLRN
Sbjct: 604  SDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRN 663

Query: 671  TTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEI 730
            T PNFVRCIIPNHEK++GKLD  LVL+QLRCNGVLEGIRICRQGFPNR+VFQEFRQRYEI
Sbjct: 664  TNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEI 723

Query: 731  LAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVI 790
            L  N+IPKGFMDGKQAC+LMIKALELD NLYRIGQSK+FFR GVLAHLEEERDLKITDVI
Sbjct: 724  LTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVI 783

Query: 791  MAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQ 850
            + FQA CRGYLARKAFAKRQQQLTAMKV+QRNCAAYLKLRNWQWWRLFTKVKPLLQV+RQ
Sbjct: 784  IGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQ 843

Query: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
            EEEM AKE+EL K +E+Q  AEN L E+E   SQL  EK  LQEQLQAETEL AEAEE+R
Sbjct: 844  EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELR 903

Query: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
             RL AKKQELEEI H++EAR+EEEE+R Q LQAE+KKM Q + +LEEQLEEEE+ARQKLQ
Sbjct: 904  ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQ 963

Query: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
            LEKVT EAK+KKLE+E ++++DQN KL+KE+KLLE+RI++ TTNL EEEEK+K+L KLKN
Sbjct: 964  LEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKN 1023

Query: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
            KHE+MI++LE RL++EEK RQELEK +RKLEGD++D  +QIA+LQAQIAELKMQLAKKEE
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083

Query: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
            ELQAALAR+++E AQKN ALKKIRELE  IS+LQEDL+SERA+RNKAEKQKRDLGEELEA
Sbjct: 1084 ELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEA 1143

Query: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
            LKTELEDTLDSTA QQELR+KREQEV +LKK L+EE ++HEAQ+QEMRQKH+QAVEEL E
Sbjct: 1144 LKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAE 1203

Query: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
            QLEQ KR KANL+K KQTLE E  +LA E++VL Q K + EHK+KK+EAQ+QELQ K ++
Sbjct: 1204 QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263

Query: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
            GER R EL DKV KLQ E+++VTG+L++++ K+ KL KD ++L SQLQDTQELLQEE RQ
Sbjct: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ 1323

Query: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEAL 1390
            KL++STKL+Q+E+E+NS ++QL+EE EAK NLE+ I+TL+ Q++D KKK++D    +E  
Sbjct: 1324 KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETA 1383

Query: 1391 EEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ 1450
            EE K++ QK++E L+Q++EEK AAYDKLEKTK RLQQELDDL+VDLD+QRQ   NLEKKQ
Sbjct: 1384 EEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ 1443

Query: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLK 1510
            +KFDQLLAEEK IS+KYA+ERDRAEAEAREKETKALSLARALEEA+E K ELER NK  +
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFR 1503

Query: 1511 AEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQ 1570
             EMEDL+SSKDDVGK+VHELEKSKRALE Q+EEMKTQLEELEDELQATEDAKLRLEVN+Q
Sbjct: 1504 TEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ 1563

Query: 1571 ALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLE 1630
            A+K QFERDLQ RDEQ+EEK++QL RQ+ E E ELEDERKQR++A AA+KKLE DLKDLE
Sbjct: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623

Query: 1631 LQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLM 1690
               DSA K R+EAIKQLRKLQAQMKD  REL+D RASR+EI A AKENEKK KS+EA+++
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683

Query: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQ-DEKRRLEARIAQLEEELEEEQ 1749
            QLQE+LAAAERA++QA  E++ELA+E+A+S SG+ AL  +EKRRLEARIAQLEEELEEEQ
Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKRRLEARIAQLEEELEEEQ 1742

Query: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 1809
            GN E ++DR++KA  Q +Q++ +L  ERS AQKNE+ARQQLERQNKEL+ KL EMEG VK
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVK 1802

Query: 1810 SKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYK 1869
            SK+K++I ALEAKIAQLEEQ++ E +E+QAA K +++ +KKLK++LLQV+DER+ AEQYK
Sbjct: 1803 SKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYK 1862

Query: 1870 EQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
            +QA+K + R+KQLKRQLEEAEEE+QR NA+RRKLQREL++ATE+ +AM REV++LK+KLR
Sbjct: 1863 DQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLR 1922



 Score =  176 bits (445), Expect = 3e-43
 Identities = 169/770 (21%), Positives = 345/770 (44%), Gaps = 97/770 (12%)

Query: 804  KAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQ-----------VTRQEE 852
            +A  +  +QL   K ++ N     +    +   L  +VK LLQ           V  Q +
Sbjct: 1196 QAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQ 1255

Query: 853  EMQAKEDELQKTK----ERQQKAENELKEL-------EQKHSQLTEEKNLLQEQLQAETE 901
            E+Q K +E ++ +    ++  K + EL  +       + K S+LT++ + L+ QLQ   E
Sbjct: 1256 ELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQE 1315

Query: 902  LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEE 961
            L  E    ++ L+ K +++E+  +    +LEEEE+    L+ +   +  Q+ D+++++E+
Sbjct: 1316 LLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMED 1375

Query: 962  -----EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA 1016
                 E A   K +L+K   E   ++ E+++   D    KL K +  L++ + DL  +L 
Sbjct: 1376 SVGCLETAEEVKRKLQK-DLEGLSQRHEEKVAAYD----KLEKTKTRLQQELDDLLVDLD 1430

Query: 1017 EEEEKAKNLTKLKNKHESMISE--------LEVRLKKEEKSRQ----------------- 1051
             + + A NL K + K + +++E         E R + E ++R+                 
Sbjct: 1431 HQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAME 1490

Query: 1052 ---ELEKLKRKLEGDASDFHEQIADLQAQIAEL---KMQLAKKEEELQAALARLDDEIAQ 1105
               ELE+L ++   +  D      D+   + EL   K  L ++ EE++  L  L+DE+  
Sbjct: 1491 QKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA 1550

Query: 1106 KNNALKKIRELEGHISDLQEDLDSERAARNK-AEKQKRDLGEELEALKTELEDTLDSTAT 1164
              +A  K+R LE ++  ++   + +   R++ +E++K+ L  ++  ++ ELED     + 
Sbjct: 1551 TEDA--KLR-LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSM 1607

Query: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE-------QLEQFKR 1217
                R K E ++  L+  +D   ++ +  ++++R+  AQ  + + E       + E   +
Sbjct: 1608 AVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQ 1667

Query: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK---------------------KKK 1256
            AK N +K  +++E E   L  EL    +AK++ + +                     K++
Sbjct: 1668 AKEN-EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR 1726

Query: 1257 LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
            LEA++ +L+ +  + +     +ND++ K   +++ +   LN     A K       L  Q
Sbjct: 1727 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQ 1786

Query: 1317 LQDTQELLQE-ETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
             ++ +  LQE E   K      +  LE +   L++QLD E + +Q   + +     +L D
Sbjct: 1787 NKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846

Query: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
               ++ D     E  ++   +    ++ L +Q EE      +   ++ +LQ+EL+D    
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATET 1906

Query: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
             D   + VS+L+ K R+ D      + ++ K A +    E + +    +A
Sbjct: 1907 ADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEA 1956


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 2459 bits (6374), Expect = 0.0
 Identities = 1226/1906 (64%), Positives = 1561/1906 (81%), Gaps = 3/1906 (0%)

Query: 27   QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
            Q +W A+RLVWVPSE  GFEAA++++E  +E  VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 87   VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
             EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 147  RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
            RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 207  DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266
            +  + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL
Sbjct: 227  EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286

Query: 267  EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMF 326
            EKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE  ++Y FL+NG    P  Q+ E+F
Sbjct: 287  EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERELF 345

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
            QET+E++ ++GFS EE +S+L++VS+VLQ GNI  K+ERNTDQA+MPDNTAAQK+C L+G
Sbjct: 346  QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405

Query: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
            + VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ R+N+ALD+
Sbjct: 406  LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            + RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W
Sbjct: 466  SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKP 566
             F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+  EQG HPKFQ+P
Sbjct: 526  TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585

Query: 567  KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626
            + L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+  A++WKDV+ IV
Sbjct: 586  RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645

Query: 627  GLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKR 686
            GL+Q++ + +   P   + ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR
Sbjct: 646  GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703

Query: 687  SGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQA 746
            +GKL+  LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL  NAIPKGFMDGKQA
Sbjct: 704  AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763

Query: 747  CILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAF 806
            C  MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA  RGYLAR+AF
Sbjct: 764  CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823

Query: 807  AKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKE 866
             KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+  ELQK +E
Sbjct: 824  QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883

Query: 867  RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
             QQ++  E+ EL+ + +QL EE+  L EQL+AE EL AEAEE R RLAA+KQELE ++ E
Sbjct: 884  LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943

Query: 927  MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986
            +EAR+ EEE+  +Q+Q E+K++ Q + +LE  LE EE ARQKLQLEKVT EAK+KK E++
Sbjct: 944  LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003

Query: 987  ILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046
            +L+++DQN+KLSKERKLLE+R+++ ++  AEEEEK K+L KL+ K+E+ I+++E RL+KE
Sbjct: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063

Query: 1047 EKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106
            EK RQELEKLKR+L+G++S+  EQ+ + Q +  EL+ QL +KEEELQAALAR +DE   +
Sbjct: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123

Query: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1166
               LK +RE +  +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST  QQ
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183

Query: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1226
            ELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R K   +K +
Sbjct: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243

Query: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
              LE E ++L  EL  L  A+QE E ++++LE Q+QE+Q +  DGERARAE  +K+ + Q
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303

Query: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
             E+E+V+G LNEAE K I+L+K+++S  +QL D QELLQEETR KL + +++R +E E  
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363

Query: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
             L++QL+EE  A++   R + T   QLS+ +++ ++ A  +EA EE ++R  +E E LTQ
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423

Query: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
            +  EK    D+LE+ + RLQQELDD  +DL+ QRQLVS LEKKQRKFDQLLAEEK    +
Sbjct: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483

Query: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
              +ER+RAEAE RE+E +ALSL RALEE  EA+EELER N+ L+AE+E L+SSKDDVGK+
Sbjct: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543

Query: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
            VHELE++ R  E    +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE 
Sbjct: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603

Query: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
             EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q  SA +G+EEA+KQ
Sbjct: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663

Query: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
            LRK+QAQMK+  RE+E+ R SR+EIF+  +E+EK+ K LEA++++LQE+LAA++RAR+QA
Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723

Query: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
              +++E+A+E+A+    + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK   Q 
Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783

Query: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
            E L+ EL+ ERS + K ES RQQLERQ +ELR +L E +   +++ K TIAALE+K+AQ 
Sbjct: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843

Query: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
            EEQ+EQE RE+  + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQL
Sbjct: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903

Query: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1932
            EEAEEE+ R  A RR+LQREL++ TES E+M REV  L+++LR  P
Sbjct: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1949



 Score =  210 bits (534), Expect = 1e-53
 Identities = 232/994 (23%), Positives = 426/994 (42%), Gaps = 132/994 (13%)

Query: 846  QVTRQEEEMQAK-------EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 898
            Q   +EE++++        E  +   ++R +K E   +ELE+   +L  E + LQEQ+  
Sbjct: 1031 QAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM-- 1088

Query: 899  ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 958
              E    AEE+R +L  K++EL+  L    AR E+E     QL    ++    + + +E 
Sbjct: 1089 -VEQQQRAEELRAQLGRKEEELQAAL----ARAEDEGGARAQLLKSLREAQAALAEAQED 1143

Query: 959  LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
            LE E  AR K + ++     +++ L  E+    D  N   + R   E+ +++L   L EE
Sbjct: 1144 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1203

Query: 1019 EE-KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
                   + +L+ +H   + EL  +L++  + +   EK +  LE + S+   +++ LQ  
Sbjct: 1204 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1263

Query: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
              E + +  + E +LQ    R  D    +  A +K++         Q +L++   A N+A
Sbjct: 1264 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRA-------QAELENVSGALNEA 1316

Query: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAK---------REQEVTVLKKALDEETR 1188
            E +   L +EL + + +L D  +    Q+E RAK          E E   L++ L+EE  
Sbjct: 1317 ESKTIRLSKELSSTEAQLHDAQE--LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAA 1374

Query: 1189 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
            + E   +E++   AQ  E    Q E+    +A  +  ++   +  A L   L    +   
Sbjct: 1375 ARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA-LTQRLAEKTETVD 1433

Query: 1249 EVEHKKKKLEAQVQELQSKCSDGERAR---AELNDKVHK----LQNEVESVTGMLNE--- 1298
             +E  +++L+   QEL     D E+ R   + L  K  K    L  E  +V   + E   
Sbjct: 1434 RLERGRRRLQ---QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERER 1490

Query: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
            AE +  +      SL+  L++ QE  +E  RQ        R L  E  +L    D+  ++
Sbjct: 1491 AEAEGREREARALSLTRALEEEQEAREELERQN-------RALRAELEALLSSKDDVGKS 1543

Query: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
               LER         +D + ++ +    + A E+ K R +  ++ L  Q+E      D+ 
Sbjct: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603

Query: 1419 -EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
             E+ + +L ++L D  V+ D +R+  +     ++K +  L E K   +     ++ A  +
Sbjct: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663

Query: 1478 AREKETKALSLARALEEALEAKEEL-------ERTNKMLKAEM----EDLVSS------- 1519
             R+ + +   L R +EE   ++EE+       E+  K L+AE+    E+L +S       
Sbjct: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723

Query: 1520 ---KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED---------AKLRLEV 1567
               +D++   V     SK A+  +  +++ +L +LE+EL+  +           KL L+V
Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783

Query: 1568 NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY-------------------------- 1601
                 +   ER   A+ E     R+QL+RQ+ E                           
Sbjct: 1784 ESLTTELSAERSFSAKAESG---RQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1840

Query: 1602 ---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1658
               E +LE E ++R L+    ++ E  LK++ LQ +   +  ++   QL K   ++K  +
Sbjct: 1841 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1900

Query: 1659 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL- 1717
            R+LE+A              E++A   +A   +LQ +L     + +  + E   L   L 
Sbjct: 1901 RQLEEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946

Query: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751
               L+       +  RLE  +A  EE  E + G+
Sbjct: 1947 RGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1980


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 2452 bits (6355), Expect = 0.0
 Identities = 1226/1914 (64%), Positives = 1561/1914 (81%), Gaps = 11/1914 (0%)

Query: 27   QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
            Q +W A+RLVWVPSE  GFEAA++++E  +E  VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 87   VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
             EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 147  RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
            RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 207  DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
            +  +         GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286

Query: 259  ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
            ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE  ++Y FL+NG    P
Sbjct: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346

Query: 319  AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
              Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 347  G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405

Query: 379  QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
            QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ 
Sbjct: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465

Query: 439  RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
            R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525

Query: 499  YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
            YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+  EQG
Sbjct: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585

Query: 559  SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
             HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+  A++
Sbjct: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 619  WKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRC 678
            WKDV+ IVGL+Q++ + +   P   + ++GMFRTVGQLYKE L +LM TL NT P+FVRC
Sbjct: 646  WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703

Query: 679  IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 738
            I+PNHEKR+GKL+  LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL  NAIPK
Sbjct: 704  IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763

Query: 739  GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 798
            GFMDGKQAC  MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA  R
Sbjct: 764  GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823

Query: 799  GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
            GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ 
Sbjct: 824  GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883

Query: 859  DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918
             ELQK +E QQ++  E+ EL+ + +QL EE+  L EQL+AE EL AEAEE R RLAA+KQ
Sbjct: 884  QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943

Query: 919  ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978
            ELE ++ E+EAR+ EEE+  +Q+Q E+K++ Q + +LE  LE EE ARQKLQLEKVT EA
Sbjct: 944  ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003

Query: 979  KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
            K+KK E+++L+++DQN+KLSKERKLLE+R+++ ++  AEEEEK K+L KL+ K+E+ I++
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063

Query: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
            +E RL+KEEK RQELEKLKR+L+G++S+  EQ+ + Q +  EL+ QL +KEEELQAALAR
Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123

Query: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT 1158
             +DE   +   LK +RE +  +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183

Query: 1159 LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1218
            LDST  QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R 
Sbjct: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243

Query: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
            K   +K +  LE E ++L  EL  L  A+QE E ++++LE Q+QE+Q +  DGERARAE 
Sbjct: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303

Query: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
             +K+ + Q E+E+V+G LNEAE K I+L+K+++S  +QL D QELLQEETR KL + +++
Sbjct: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363

Query: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
            R +E E   L++QL+EE  A++   R + T   QLS+ +++ ++ A  +EA EE ++R  
Sbjct: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423

Query: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
            +E E LTQ+  EK    D+LE+ + RLQQELDD  +DL+ QRQLVS LEKKQRKFDQLLA
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483

Query: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
            EEK    +  +ER+RAEAE RE+E +ALSL RALEE  EA+EELER N+ L+AE+E L+S
Sbjct: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543

Query: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
            SKDDVGK+VHELE++ R  E    +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ER
Sbjct: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603

Query: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
            DLQ RDE  EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q  SA +
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663

Query: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
            G+EEA+KQLRK+QAQMK+  RE+E+ R SR+EIF+  +E+EK+ K LEA++++LQE+LAA
Sbjct: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723

Query: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
            ++RAR+QA  +++E+A+E+A+    + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR
Sbjct: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783

Query: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
             RK   Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E +   +++ K TIAA
Sbjct: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843

Query: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
            LE+K+AQ EEQ+EQE RE+  + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN R
Sbjct: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903

Query: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1932
            VKQLKRQLEEAEEE+ R  A RR+LQREL++ TES E+M REV  L+++LR  P
Sbjct: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1957



 Score =  210 bits (534), Expect = 1e-53
 Identities = 232/994 (23%), Positives = 426/994 (42%), Gaps = 132/994 (13%)

Query: 846  QVTRQEEEMQAK-------EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 898
            Q   +EE++++        E  +   ++R +K E   +ELE+   +L  E + LQEQ+  
Sbjct: 1039 QAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM-- 1096

Query: 899  ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 958
              E    AEE+R +L  K++EL+  L    AR E+E     QL    ++    + + +E 
Sbjct: 1097 -VEQQQRAEELRAQLGRKEEELQAAL----ARAEDEGGARAQLLKSLREAQAALAEAQED 1151

Query: 959  LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
            LE E  AR K + ++     +++ L  E+    D  N   + R   E+ +++L   L EE
Sbjct: 1152 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1211

Query: 1019 EE-KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
                   + +L+ +H   + EL  +L++  + +   EK +  LE + S+   +++ LQ  
Sbjct: 1212 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1271

Query: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
              E + +  + E +LQ    R  D    +  A +K++         Q +L++   A N+A
Sbjct: 1272 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRA-------QAELENVSGALNEA 1324

Query: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAK---------REQEVTVLKKALDEETR 1188
            E +   L +EL + + +L D  +    Q+E RAK          E E   L++ L+EE  
Sbjct: 1325 ESKTIRLSKELSSTEAQLHDAQE--LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAA 1382

Query: 1189 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
            + E   +E++   AQ  E    Q E+    +A  +  ++   +  A L   L    +   
Sbjct: 1383 ARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA-LTQRLAEKTETVD 1441

Query: 1249 EVEHKKKKLEAQVQELQSKCSDGERAR---AELNDKVHK----LQNEVESVTGMLNE--- 1298
             +E  +++L+   QEL     D E+ R   + L  K  K    L  E  +V   + E   
Sbjct: 1442 RLERGRRRLQ---QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERER 1498

Query: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
            AE +  +      SL+  L++ QE  +E  RQ        R L  E  +L    D+  ++
Sbjct: 1499 AEAEGREREARALSLTRALEEEQEAREELERQN-------RALRAELEALLSSKDDVGKS 1551

Query: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
               LER         +D + ++ +    + A E+ K R +  ++ L  Q+E      D+ 
Sbjct: 1552 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1611

Query: 1419 -EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
             E+ + +L ++L D  V+ D +R+  +     ++K +  L E K   +     ++ A  +
Sbjct: 1612 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1671

Query: 1478 AREKETKALSLARALEEALEAKEEL-------ERTNKMLKAEM----EDLVSS------- 1519
             R+ + +   L R +EE   ++EE+       E+  K L+AE+    E+L +S       
Sbjct: 1672 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1731

Query: 1520 ---KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED---------AKLRLEV 1567
               +D++   V     SK A+  +  +++ +L +LE+EL+  +           KL L+V
Sbjct: 1732 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1791

Query: 1568 NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY-------------------------- 1601
                 +   ER   A+ E     R+QL+RQ+ E                           
Sbjct: 1792 ESLTTELSAERSFSAKAESG---RQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1848

Query: 1602 ---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1658
               E +LE E ++R L+    ++ E  LK++ LQ +   +  ++   QL K   ++K  +
Sbjct: 1849 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1908

Query: 1659 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL- 1717
            R+LE+A              E++A   +A   +LQ +L     + +  + E   L   L 
Sbjct: 1909 RQLEEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954

Query: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751
               L+       +  RLE  +A  EE  E + G+
Sbjct: 1955 RGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1988


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 2435 bits (6311), Expect = 0.0
 Identities = 1226/1947 (62%), Positives = 1561/1947 (80%), Gaps = 44/1947 (2%)

Query: 27   QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
            Q +W A+RLVWVPSE  GFEAA++++E  +E  VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 47   QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106

Query: 87   VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
             EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 107  AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166

Query: 147  RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
            RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 167  RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226

Query: 207  DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
            +  +         GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 227  EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286

Query: 259  ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
            ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE  ++Y FL+NG    P
Sbjct: 287  ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346

Query: 319  AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
              Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI  K+ERNTDQA+MPDNTAA
Sbjct: 347  G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405

Query: 379  QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
            QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ 
Sbjct: 406  QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465

Query: 439  RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
            R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 466  RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525

Query: 499  YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
            YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+  EQG
Sbjct: 526  YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585

Query: 559  SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
             HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+  A++
Sbjct: 586  GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645

Query: 619  WKD---------------------------------VDRIVGLDQMAKMTESSLPSASKT 645
            WKD                                 V+ IVGL+Q++ + +   P   + 
Sbjct: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDG--PPGGRP 703

Query: 646  KKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVL 705
            ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR+GKL+  LVL+QLRCNGVL
Sbjct: 704  RRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVL 763

Query: 706  EGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQ 765
            EGIRICRQGFPNRI+FQEFRQRYEIL  NAIPKGFMDGKQAC  MI+ALELDPNLYR+GQ
Sbjct: 764  EGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQ 823

Query: 766  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
            SKIFFR GVLA LEEERDLK+TD+I++FQA  RGYLAR+AF KRQQQ +A++V+QRNCAA
Sbjct: 824  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 883

Query: 826  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQL 885
            YLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+  ELQK +E QQ++  E+ EL+ + +QL
Sbjct: 884  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 943

Query: 886  TEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAER 945
             EE+  L EQL+AE EL AEAEE R RLAA+KQELE ++ E+EAR+ EEE+  +Q+Q E+
Sbjct: 944  EEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEK 1003

Query: 946  KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE 1005
            K++ Q + +LE  LE EE ARQKLQLEKVT EAK+KK E+++L+++DQN+KLSKERKLLE
Sbjct: 1004 KRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLE 1063

Query: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
            +R+++ ++  AEEEEK K+L KL+ K+E+ I+++E RL+KEEK RQELEKLKR+L+G++S
Sbjct: 1064 DRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS 1123

Query: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
            +  EQ+ + Q +  EL+ QL +KEEELQAALAR +DE   +   LK +RE +  +++ QE
Sbjct: 1124 ELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQE 1183

Query: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
            DL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST  QQELR+KREQEVT LKK L+E
Sbjct: 1184 DLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEE 1243

Query: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
            ETR HEA VQE+RQ+H QA+ EL EQLEQ +R K   +K +  LE E ++L  EL  L  
Sbjct: 1244 ETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQT 1303

Query: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
            A+QE E ++++LE Q+QE+Q +  DGERARAE  +K+ + Q E+E+V+G LNEAE K I+
Sbjct: 1304 ARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1363

Query: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
            L+K+++S  +QL D QELLQEETR KL + +++R +E E   L++QL+EE  A++   R 
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423

Query: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL 1425
            + T   QLS+ +++ ++ A  +EA EE ++R  +E E LTQ+  EK    D+LE+ + RL
Sbjct: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483

Query: 1426 QQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKA 1485
            QQELDD  +DL+ QRQLVS LEKKQRKFDQLLAEEK    +  +ER+RAEAE RE+E +A
Sbjct: 1484 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1543

Query: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMK 1545
            LSL RALEE  EA+EELER N+ L+AE+E L+SSKDDVGK+VHELE++ R  E    +++
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603

Query: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
             Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE  EE+RRQL +QL + E E 
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVER 1663

Query: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
            ++ERKQR LA AA+KKLEG+L++L+ Q  SA +G+EEA+KQLRK+QAQMK+  RE+E+ R
Sbjct: 1664 DEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1723

Query: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRN 1725
             SR+EIF+  +E+EK+ K LEA++++LQE+LAA++RAR+QA  +++E+A+E+A+    + 
Sbjct: 1724 TSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKA 1783

Query: 1726 ALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNES 1785
            A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK   Q E L+ EL+ ERS + K ES
Sbjct: 1784 AILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAES 1843

Query: 1786 ARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLK 1845
             RQQLERQ +ELR +L E +   +++ K TIAALE+K+AQ EEQ+EQE RE+  + K ++
Sbjct: 1844 GRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1903

Query: 1846 QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQR 1905
            + +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQLEEAEEE+ R  A RR+LQR
Sbjct: 1904 RAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQR 1963

Query: 1906 ELDEATESNEAMGREVNALKSKLRGPP 1932
            EL++ TES E+M REV  L+++LR  P
Sbjct: 1964 ELEDVTESAESMNREVTTLRNRLRRGP 1990



 Score =  210 bits (534), Expect = 1e-53
 Identities = 232/994 (23%), Positives = 426/994 (42%), Gaps = 132/994 (13%)

Query: 846  QVTRQEEEMQAK-------EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 898
            Q   +EE++++        E  +   ++R +K E   +ELE+   +L  E + LQEQ+  
Sbjct: 1072 QAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM-- 1129

Query: 899  ETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQ 958
              E    AEE+R +L  K++EL+  L    AR E+E     QL    ++    + + +E 
Sbjct: 1130 -VEQQQRAEELRAQLGRKEEELQAAL----ARAEDEGGARAQLLKSLREAQAALAEAQED 1184

Query: 959  LEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
            LE E  AR K + ++     +++ L  E+    D  N   + R   E+ +++L   L EE
Sbjct: 1185 LESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEE 1244

Query: 1019 EE-KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
                   + +L+ +H   + EL  +L++  + +   EK +  LE + S+   +++ LQ  
Sbjct: 1245 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304

Query: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
              E + +  + E +LQ    R  D    +  A +K++         Q +L++   A N+A
Sbjct: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRA-------QAELENVSGALNEA 1357

Query: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAK---------REQEVTVLKKALDEETR 1188
            E +   L +EL + + +L D  +    Q+E RAK          E E   L++ L+EE  
Sbjct: 1358 ESKTIRLSKELSSTEAQLHDAQE--LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAA 1415

Query: 1189 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
            + E   +E++   AQ  E    Q E+    +A  +  ++   +  A L   L    +   
Sbjct: 1416 ARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA-LTQRLAEKTETVD 1474

Query: 1249 EVEHKKKKLEAQVQELQSKCSDGERAR---AELNDKVHK----LQNEVESVTGMLNE--- 1298
             +E  +++L+   QEL     D E+ R   + L  K  K    L  E  +V   + E   
Sbjct: 1475 RLERGRRRLQ---QELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERER 1531

Query: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEA 1358
            AE +  +      SL+  L++ QE  +E  RQ        R L  E  +L    D+  ++
Sbjct: 1532 AEAEGREREARALSLTRALEEEQEAREELERQN-------RALRAELEALLSSKDDVGKS 1584

Query: 1359 KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKL 1418
               LER         +D + ++ +    + A E+ K R +  ++ L  Q+E      D+ 
Sbjct: 1585 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1644

Query: 1419 -EKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
             E+ + +L ++L D  V+ D +R+  +     ++K +  L E K   +     ++ A  +
Sbjct: 1645 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1704

Query: 1478 AREKETKALSLARALEEALEAKEEL-------ERTNKMLKAEM----EDLVSS------- 1519
             R+ + +   L R +EE   ++EE+       E+  K L+AE+    E+L +S       
Sbjct: 1705 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1764

Query: 1520 ---KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATED---------AKLRLEV 1567
               +D++   V     SK A+  +  +++ +L +LE+EL+  +           KL L+V
Sbjct: 1765 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1824

Query: 1568 NMQALKGQFERDLQARDEQNEEKRRQLQRQLHEY-------------------------- 1601
                 +   ER   A+ E     R+QL+RQ+ E                           
Sbjct: 1825 ESLTTELSAERSFSAKAESG---RQQLERQIQELRGRLGEEDAGARARHKMTIAALESKL 1881

Query: 1602 ---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ 1658
               E +LE E ++R L+    ++ E  LK++ LQ +   +  ++   QL K   ++K  +
Sbjct: 1882 AQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLK 1941

Query: 1659 RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL- 1717
            R+LE+A              E++A   +A   +LQ +L     + +  + E   L   L 
Sbjct: 1942 RQLEEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1987

Query: 1718 ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751
               L+       +  RLE  +A  EE  E + G+
Sbjct: 1988 RGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 2021


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 1445 bits (3740), Expect = 0.0
 Identities = 797/1908 (41%), Positives = 1183/1908 (62%), Gaps = 27/1908 (1%)

Query: 33   KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
            K+ V+VP +KQ F  A I   +G +V  E  E GK VTV +D + + NPPKF K+EDMA 
Sbjct: 34   KKDVFVPDDKQEFVKAKIVSREGGKVTAE-TEYGKTVTVKEDQVMQQNPPKFDKIEDMAM 92

Query: 93   LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
            LT L+E +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V  Y+GKKR E PP
Sbjct: 93   LTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPP 152

Query: 153  HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSI- 210
            HI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY AV+A+   + KKD S  
Sbjct: 153  HIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPG 212

Query: 211  TGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSR 270
             G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKSR
Sbjct: 213  KGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 272

Query: 271  AIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNN---YTFLSNGFVPIPAAQDDEMFQ 327
             I Q + ER +HIFY +++  K ++   LL+   NN   Y F+S G   + +  D E   
Sbjct: 273  VIFQLKAERDYHIFYQILSNKKPELLDMLLIT--NNPYDYAFISQGETTVASIDDAEELM 330

Query: 328  ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
             T  A  ++GF+ EE+ S+ K+  +++  GN+ FK ++  +QA       A K  +LMG+
Sbjct: 331  ATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGL 390

Query: 388  NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKT 447
            N  D  + +  PR+KVG + V K Q  +Q  +A  ALAKA YER+F W++TR+N  L+ T
Sbjct: 391  NSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE-T 449

Query: 448  HRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWN 507
             +    F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW 
Sbjct: 450  KQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 509

Query: 508  FIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKP 566
            FIDFG+DLQ CI+LIE+P    G++++L+EEC FPKATD +F  KL     G    FQKP
Sbjct: 510  FIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKP 566

Query: 567  KQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
            + +K K E  FS+IHYAG VDYN   WL KN DPLN+ V  L   SS K ++ L+ +   
Sbjct: 567  RNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANY-- 624

Query: 625  IVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
              G D   +  +       K KKG  F+TV  L++E L KLMT LR+T P+FVRCIIPN 
Sbjct: 625  -AGADAPIEKGKG------KAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNE 677

Query: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
             K  G +D  LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL   AIP+G F+D
Sbjct: 678  TKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFID 737

Query: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
             ++    ++ +L++D N Y+ G +K+FF+ G+L  LEE RD +++ +I   QA  RG LA
Sbjct: 738  SRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLA 797

Query: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
            R  + K  ++  ++ VIQ N  A++ ++NW W +L+ K+KPLL+   +E+EM + ++E  
Sbjct: 798  RMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFT 857

Query: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
            + KE  +K+E   KELE+K   L +EKN LQ Q+QAE +  A+AEE   +L   K +LE 
Sbjct: 858  RLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEA 917

Query: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
             + EM  RLE+EE+   +L A+++K+  +  +L+  +++ E    K++ EK   E K+K 
Sbjct: 918  KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKN 977

Query: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
            L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +LE  
Sbjct: 978  LTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGS 1037

Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
            L++E+K R +LE+ KRKLEGD     E I DL+    +L  +L KK+ EL A  AR++DE
Sbjct: 1038 LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDE 1097

Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
             A  +   KK++EL+  I +L+E+L++ER AR K EK + DL  ELE +   LE+   +T
Sbjct: 1098 QALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGAT 1157

Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
            + Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L
Sbjct: 1158 SVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKL 1217

Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
            +K K   + E  D+   +  + +AK  +E   + LE Q+ E +SK  + +R+  +L  + 
Sbjct: 1218 EKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQR 1277

Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
             KLQ E   ++  L+E E    +L +   + + QL+D +  L+EE + K  ++  L+   
Sbjct: 1278 AKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSAR 1337

Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
             + + L++Q +EE EAK  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1338 HDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1397

Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
            +   +  E   A    LEKTK+RLQ E++DL+VD++      + L+KKQR FD++LAE K
Sbjct: 1398 QEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWK 1457

Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
                +   E + ++ EAR   T+   L  A EE+LE  E  +R NK L+ E+ DL     
Sbjct: 1458 QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLG 1517

Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
              GK +HELEK ++ LE +  E+++ LEE E  L+  E   LR ++    +K + ER L 
Sbjct: 1518 SSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577

Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
             +DE+ E+ +R   R +   +T L+ E + R  A   KKK+EGDL ++E+Q   A +   
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637

Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
            EA KQ++ LQ+ +KD Q +L+DA  + D++       E++   L+A+L +L+  +   ER
Sbjct: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697

Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
            +RK A+ E  E +E +    S   +L ++K++++A ++QL+ E+EE         ++ +K
Sbjct: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757

Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
            A   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  +  LEA
Sbjct: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEA 1817

Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
            ++ +LE ++E E +    + K +++ ++++KE+  Q E++RK   + ++  +K   +VK 
Sbjct: 1818 RVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKA 1877

Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
             KRQ EEAEE++    +  RK+Q ELDEA E  +    +VN L++K R
Sbjct: 1878 YKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925



 Score =  208 bits (530), Expect = 4e-53
 Identities = 201/966 (20%), Positives = 430/966 (44%), Gaps = 132/966 (13%)

Query: 839  TKVKPLLQVTRQE--EEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
            TK K  LQ   Q+  +++QA+ED++    + + K E ++ +LE     L +EK +  +  
Sbjct: 993  TKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLE---GSLEQEKKVRMDLE 1049

Query: 897  QAETELYAE---AEEMRVRLAAKKQELEEILHE-------MEARLEEEEDRGQQLQAERK 946
            +A+ +L  +    +E  + L   KQ+L+E L +       + AR+E+E+  G QLQ + K
Sbjct: 1050 RAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLK 1109

Query: 947  KMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI-------LVMDDQNNKLSK 999
            ++  ++ +LEE+LE E  AR K++  +     +++++ + +        V  + N K   
Sbjct: 1110 ELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1169

Query: 1000 ERKLLEERISDLTT---------------NLAEEEEKAKNLTKLKNKHESMISELEVRL- 1043
            E + +   + + T                ++AE  E+  NL ++K K E   SE ++ L 
Sbjct: 1170 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229

Query: 1044 ------KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
                  ++  K++  LEK+ R LE   ++   +  + Q  + +L  Q AK + E      
Sbjct: 1230 DVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSR 1289

Query: 1098 RLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
            +LD++ A  +   +        + DL+  L+ E  A+N      +    + + L+ + E+
Sbjct: 1290 QLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349

Query: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
              ++ A  Q + +K   EV   +   + +      +++E ++K AQ ++E  E +E    
Sbjct: 1350 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNA 1409

Query: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA-------QVQELQSKCSD 1270
              ++L+K K  L+ E  DL  ++     A   ++ K++  +        + +E QS+   
Sbjct: 1410 KCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES 1469

Query: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQ 1330
             ++    L+ ++ KL+N  E     L   + +   L ++++ L+ QL  + + + E  + 
Sbjct: 1470 SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKV 1529

Query: 1331 KLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEA 1389
            +       +QLE E+  LQ  L+E   + ++ E  I    ++ +  K +++   A   E 
Sbjct: 1530 R-------KQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1582

Query: 1390 LEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 1449
            +E+ K+   + +++L    + +  + ++  + K +++ +L+++ + L +  ++ +  +K+
Sbjct: 1583 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1642

Query: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREK----ETKALSLARALEEALEAKEELERT 1505
             +    LL +    +    D+  RA  + +E     E +   L   LEE     E+ ER+
Sbjct: 1643 VKSLQSLLKD----TQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698

Query: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE--------------- 1550
             K+ + E+ +       +      L   K+ ++  + +++T++EE               
Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758

Query: 1551 ------LEDELQATEDAKLRLE---VNMQ----------------ALKG----------- 1574
                  + +EL+  +D    LE    NM+                ALKG           
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818

Query: 1575 --QFERDLQARDEQNEEK---RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDL 1629
              + E +L+A  ++N E     R+ +R++ E   + E++RK          +L+  +  L
Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL-------RLQDLVDKL 1871

Query: 1630 ELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADL 1689
            +L+  +  +  EEA +Q     ++ +  Q EL++A    D   A ++ N+ +AKS +   
Sbjct: 1872 QLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERAD--IAESQVNKLRAKSRDIGT 1929

Query: 1690 MQLQED 1695
              L E+
Sbjct: 1930 KGLNEE 1935


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 1435 bits (3714), Expect = 0.0
 Identities = 789/1911 (41%), Positives = 1189/1911 (62%), Gaps = 31/1911 (1%)

Query: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
            AK  V+V   K+ +  ++I+ ++G +V V+  E G  +TV +D +  MNPPK+ K+EDMA
Sbjct: 36   AKTSVFVAEPKESYVKSTIQSKEGGKVTVK-TEGGATLTVREDQVFPMNPPKYDKIEDMA 94

Query: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
             +T L+E  VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 95   MMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 154

Query: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KKD S  
Sbjct: 155  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGK 214

Query: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
            + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKS
Sbjct: 215  MQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 274

Query: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMFQE 328
            R   Q + ER++HIFY + +  K  +   LL+     +Y F+S G + +P+  D E    
Sbjct: 275  RVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMA 334

Query: 329  TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388
            T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +L  +N
Sbjct: 335  TDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLN 394

Query: 389  VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448
              D  +++  PR+KVG + V K QT +Q   AV ALAKA YE++F W++TR+N+ LD T 
Sbjct: 395  SADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLD-TK 453

Query: 449  RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508
            +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW F
Sbjct: 454  QPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513

Query: 509  IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPK 567
            IDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQKPK
Sbjct: 514  IDFGMDLAACIELIEKPL---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPK 570

Query: 568  QLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
             +K K E  FS+IHYAG VDYN + WL KN DPLND V  L   S+ K +A L+      
Sbjct: 571  VVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTY--- 627

Query: 626  VGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685
                  +   +SS    +K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN  K
Sbjct: 628  -----ASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETK 682

Query: 686  RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGK 744
              G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D K
Sbjct: 683  TPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSK 742

Query: 745  QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARK 804
            +A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA+CRG+L R 
Sbjct: 743  KASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRV 802

Query: 805  AFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKT 864
             + K  Q+  A+  IQ N  A++ +++W W +LF K+KPLL+    E+EM   ++E QKT
Sbjct: 803  EYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKT 862

Query: 865  KERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEIL 924
            K+   K+E + KELE+K   L +EKN LQ Q+Q+E +  A+AEE   +L   K +LE  +
Sbjct: 863  KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKI 922

Query: 925  HEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
             E+  R EEEE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K L 
Sbjct: 923  KEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 982

Query: 985  DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
            +E+  +D+   KLSKE+K L+E       +L  EE+K   LTK K K E  + +LE  L+
Sbjct: 983  EEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLE 1042

Query: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIA 1104
            +E+K R +LE+ KRKLEGD     E   D++    +L  +L KKE E+   +++++DE A
Sbjct: 1043 QEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQA 1102

Query: 1105 QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTAT 1164
             +    KKI+EL+  I +L E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T+ 
Sbjct: 1103 VEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1162

Query: 1165 QQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK 1224
            Q EL  KRE E   L++ L+E T  HEA V  +R+KHA ++ EL EQ++  +R K  L+K
Sbjct: 1163 QVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEK 1222

Query: 1225 NKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHK 1284
             K  L+ E  DL+     + +AK  +E   + LE QV EL++K  + +R   +L  +  +
Sbjct: 1223 EKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRAR 1282

Query: 1285 LQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEE 1344
            LQ E    +  L+E +    +L++   + + Q+++ +  L+EET+ K  ++  L+    +
Sbjct: 1283 LQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHD 1342

Query: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIEN 1403
             + L++Q +EE E K  L+R +S  N +++  + K + D     E LEE KK+  + ++ 
Sbjct: 1343 CDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQE 1402

Query: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNI 1463
              +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++L+E K  
Sbjct: 1403 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWK-- 1460

Query: 1464 SSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDLVS 1518
              KY  E  +AE EA +KE+++LS     +    EE+L+  E L R NK L+ E+ DL  
Sbjct: 1461 -QKY--EETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTE 1517

Query: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
               + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R
Sbjct: 1518 QIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1577

Query: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
             +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +
Sbjct: 1578 KIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANR 1637

Query: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
               E+++  R  Q  +K+ Q  L+DA   ++++       E++A  L+A++ +L   L  
Sbjct: 1638 LAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ 1697

Query: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
             ER+RK A+ E  + +E +    +   +L + K++LE  ++QL+ E+EE         ++
Sbjct: 1698 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEK 1757

Query: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
             +KA   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K  I  
Sbjct: 1758 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1817

Query: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
            LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+
Sbjct: 1818 LEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAK 1877

Query: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
            VK  KRQ EEAEE+S    +  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1878 VKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSR 1928



 Score =  226 bits (575), Expect = 2e-58
 Identities = 225/1022 (22%), Positives = 452/1022 (44%), Gaps = 121/1022 (11%)

Query: 836  RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
            +L  K+K + +   +EEE+ A+   + +K ++   + + ++ +LE   +++ +EK+  + 
Sbjct: 917  QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976

Query: 895  QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
            +++  TE  A  +E   +L+ +K+ L+E   +    L+ EED+   L   + K+ QQ+ D
Sbjct: 977  KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036

Query: 955  LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
            LE  LE+E+  R  L+  K   E  +K  ++  + M++   +L ++ +  E  IS+L + 
Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK 1096

Query: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
            + +E+     L K   + ++ I EL   ++ E  SR + EK +  L  +  +  E++ + 
Sbjct: 1097 IEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1156

Query: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSERAA 1133
                +       K+E E Q     L++   Q    +  +R+     +++L E +D+ +  
Sbjct: 1157 GGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRV 1216

Query: 1134 RNKAEKQKRDLGEE-----------------LEALKTELEDTLDSTATQQELRAKREQEV 1176
            + K EK+K +L  E                 LE +   LED +    T++E + +   ++
Sbjct: 1217 KQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDL 1276

Query: 1177 TVLKKALDEETRSHEAQVQEM----------RQKHAQAVEELTEQLEQFKRAKANL---- 1222
            T  +  L  E   +  Q+ E           +Q   Q +EEL  QLE+  +AK  L    
Sbjct: 1277 TAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHAL 1336

Query: 1223 -------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKKKL 1257
                   D  ++  E+E    A   R L +A  EV                  E  KKKL
Sbjct: 1337 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1396

Query: 1258 EAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
              ++QE +       +KC+  E+ +  L ++V  L  +VE         + K     K +
Sbjct: 1397 AQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVL 1456

Query: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
            +    + ++TQ  L+   ++  ++ST+L +++       DQL+      +NL++ IS L 
Sbjct: 1457 SEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516

Query: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
             Q+++  K++ +     + +E+ K   Q  +E      E +     +++   N+++ E+D
Sbjct: 1517 EQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD 1576

Query: 1431 DLVVDLDNQ------------RQLVSNLEKKQRKFDQLLAEEK-------------NISS 1465
              + + D +              + S L+ + R  +  L  +K             N ++
Sbjct: 1577 RKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHAN 1636

Query: 1466 KYADE--RDRAEAEAREKETKALSLARALEEALEAKEEL---ERTNKMLKAEMEDLVSSK 1520
            + A E  R+    +   KET+ L L  AL    + KE+L   ER   +L+AE+E+L ++ 
Sbjct: 1637 RLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATL 1695

Query: 1521 D--------------DVGKNVHELE-------KSKRALETQMEEMKTQLEELEDELQATE 1559
            +              D  + V  L         +K+ LE  + ++++++EE+  E +  E
Sbjct: 1696 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE 1755

Query: 1560 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 1619
            + K +  +   A+  +  +  Q      E  ++ L++ + + +  L DE +Q AL    K
Sbjct: 1756 E-KAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL-DEAEQLALKGGKK 1813

Query: 1620 K--KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKE 1677
            +  KLE  +++LE + ++  K   EA+K LRK + ++K+   + E+ R +   +     +
Sbjct: 1814 QIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDK 1873

Query: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
             + K KS +    + +E   A     ++   E EE  E    + S  N L+ + R +  +
Sbjct: 1874 LQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTK 1933

Query: 1738 IA 1739
            I+
Sbjct: 1934 IS 1935



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/358 (23%), Positives = 161/358 (44%), Gaps = 55/358 (15%)

Query: 836  RLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQ 895
            R  T+V   +Q T  + E++++ D L+  K    K E +L E+E    QL     L  E 
Sbjct: 1591 RNHTRVVETMQSTL-DAEIRSRNDALRVKK----KMEGDLNEME---IQLNHANRLAAES 1642

Query: 896  LQ---------AETELYAE-----AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQL 941
            L+          ET+L+ +      E+++ +LA     +E   + ++A +EE     +Q 
Sbjct: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI----VERRANLLQAEIEELWATLEQT 1698

Query: 942  QAERKKMAQQMLDLEEQLE----------------EEEAARQKLQLEKV-----TAEAKI 980
            +  RK   Q++LD  E+++                E + ++ + ++E+V      AE K 
Sbjct: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758

Query: 981  KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1032
            KK       + +E+    D +  L + +K LE+ + DL   L E E+ A K   K   K 
Sbjct: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818

Query: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
            E+ + ELE  ++ E+K   E  K  RK E    +   Q  + +  +  L+  + K + ++
Sbjct: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878

Query: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
            ++   + ++   Q N  L K R+L+  + + +E  D   +  NK   + R++  ++ A
Sbjct: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISA 1936



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 58/223 (26%), Positives = 101/223 (45%), Gaps = 29/223 (13%)

Query: 839  TKVKPLLQVTRQEEEMQAKEDELQKTKERQQKA-------ENELKELEQKHSQLTEEKNL 891
            TK K    V++ + E++    E +  +E+ +KA         ELK+ +   + L   K  
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788

Query: 892  LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR---LEEEEDRGQQLQAER--- 945
            L++ ++       EAE++ ++   KKQ     + ++EAR   LE E +  Q+  AE    
Sbjct: 1789 LEQTVKDLQHRLDEAEQLALK-GGKKQ-----IQKLEARVRELEGEVENEQKRNAEAVKG 1842

Query: 946  -KKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNN-KLSKERKL 1003
             +K  +++ +L  Q EE+     +LQ      +AK+K  + +    ++Q+N  LSK RKL
Sbjct: 1843 LRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKL 1902

Query: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046
              E        L E EE+A       NK      E+  ++  E
Sbjct: 1903 QHE--------LEEAEERADIAESQVNKLRVKSREVHTKISAE 1937


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score = 1432 bits (3706), Expect = 0.0
 Identities = 783/1903 (41%), Positives = 1173/1903 (61%), Gaps = 23/1903 (1%)

Query: 37   WVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCL 96
            +VP +K+ F  A I   +G +V+ E  ENGK VTV +D + + NPPKF K+EDMA LT L
Sbjct: 38   FVPDDKEEFVKAKILSREGGKVIAE-TENGKTVTVKEDQVLQQNPPKFDKIEDMAMLTFL 96

Query: 97   NEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYA 156
            +E +VL NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V  Y+GKKR E PPHI++
Sbjct: 97   HEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFS 156

Query: 157  IADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS-SHKGKKDTSIT--GE 213
            I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+   +GKKD +    G 
Sbjct: 157  ISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGT 216

Query: 214  LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIR 273
            LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKSR I 
Sbjct: 217  LEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIF 276

Query: 274  QARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETVE 331
            Q + ER +HIFY +++  K ++  D+LL   N  +Y F+S G V + +  D E    T  
Sbjct: 277  QLKAERNYHIFYQILSNKKPELL-DMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDS 335

Query: 332  AMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTD 391
            A  ++GF+ EE+  + K+  +++  GN+ FK+++  +QA       A K  +LMG+N  D
Sbjct: 336  AFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSAD 395

Query: 392  FTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQG 451
              + +  PR+KVG + V K Q+ +Q  +++ ALAKA YE++F W++TR+N  L+ T +  
Sbjct: 396  LLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLE-TKQPR 454

Query: 452  ASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF 511
              F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW FIDF
Sbjct: 455  QYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDF 514

Query: 512  GLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQLK 570
            G+DLQ CI+LIE+P    G++++L+EEC FPKATD +F  KL     G    FQKP+ +K
Sbjct: 515  GMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIK 571

Query: 571  DKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
             K E  FS+IHYAG VDYN   WL KN DPLN+ V +L   SS K +A L+         
Sbjct: 572  GKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSY------ 625

Query: 629  DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
               A   +S      K K   F+TV  L++E L KLMT LR T P+FVRCIIPN  K  G
Sbjct: 626  -ATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPG 684

Query: 689  KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDGKQAC 747
             +D  LV+ QLRCNGVLEGIRICR+GFPNRI++ +FRQRY IL   AIP+G F+D ++  
Sbjct: 685  VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRKGT 744

Query: 748  ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
              ++ +L++D N Y+ G +K+FF+ G+L  LEE RD +++ +I   QA  RG L R  F 
Sbjct: 745  EKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFK 804

Query: 808  KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
            K  ++  A+ VIQ N  A++ ++NW W +L+ K+KPLL+    E+EM   ++E  + KE 
Sbjct: 805  KIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKET 864

Query: 868  QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
             +K+E   KELE+K   L +EKN LQ Q+QAE +   +AEE   +L   K +LE  + EM
Sbjct: 865  LEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEM 924

Query: 928  EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
              RLE+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K L +E+
Sbjct: 925  NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 984

Query: 988  LVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE 1047
              +D+   KL+KE+K L+E       +L  EE+K  +L+K K K E  + +LE  L++E+
Sbjct: 985  AGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEK 1044

Query: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107
            K R +LE+ KRKLEGD     E I DL+    +L+ +L KKE ++    ++++DE     
Sbjct: 1045 KVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL 1104

Query: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
               KK++E +  I +L+E+L++ER AR K EK + DL  ELE +   LE+   +T+ Q E
Sbjct: 1105 QLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1164

Query: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
            +  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L+K K 
Sbjct: 1165 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1224

Query: 1228 TLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
              + E  D+   +  + +AK  +E   + LE Q  E + K  + +R+  +   +  KLQ 
Sbjct: 1225 EFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQT 1284

Query: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
            E   +   L E E    +L +   S + Q++D +  L+EE + K  ++  L+    + + 
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344

Query: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIENLTQ 1406
            L++Q +EE EAK  L+R +S  N +++  + K + D     E LEE KK+  + +++  +
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404

Query: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
              E   A    LEKTK+RLQ E++DL+VD++      + L+KKQR FD++LAE K    +
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464

Query: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
               E + ++ EAR   T+   L  A EE+LE  E  +R NK L+ E+ DL     + GKN
Sbjct: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKN 1524

Query: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
            VHELEK ++ LE +  E+++ LEE E  L+  E   LR ++    +K + ER L  +DE+
Sbjct: 1525 VHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1584

Query: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
             E+ +R  QR +   +T L+ E + R      KKK+EGDL ++E+Q   A +   EA KQ
Sbjct: 1585 MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 1644

Query: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
            ++ LQ+ +KD Q +L+DA  + D++       E++   L+A+L +L+  +   ER+RK A
Sbjct: 1645 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLA 1704

Query: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
            + E  E +E +    S   +L ++K+++E+ + QL+ E+EE         ++ +KA   A
Sbjct: 1705 EQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDA 1764

Query: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826
              ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  +  LEA++ +L
Sbjct: 1765 AMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1824

Query: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
            E ++E E +    + K +++ ++++KE+  Q E+++K   + ++  +K   +VK  KRQ 
Sbjct: 1825 EGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQA 1884

Query: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
            EEAEE++    +  RK+Q ELDEA E  +    +VN L++K R
Sbjct: 1885 EEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927



 Score =  229 bits (584), Expect = 2e-59
 Identities = 240/1034 (23%), Positives = 468/1034 (45%), Gaps = 135/1034 (13%)

Query: 836  RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
            +L  KVK + +    EEEM A+   + +K ++   + + ++ +LE   +++ +EK+  + 
Sbjct: 916  QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 975

Query: 895  QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
            +++  TE  A  +E+  +L  +K+ L+E   +    L+ EED+   L   + K+ QQ+ D
Sbjct: 976  KVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDD 1035

Query: 955  LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER--ISDLT 1012
            LE  LE+E+  R  L+  K   E  +K  ++ I  MD +N+KL  E KL ++   I+   
Sbjct: 1036 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESI--MDLENDKLQLEEKLKKKEFDINQQN 1093

Query: 1013 TNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIA 1072
            + + +E+  A  L K   ++++ I ELE  L+ E  +R ++EKL+  L  +  +  E++ 
Sbjct: 1094 SKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLE 1153

Query: 1073 DLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSER 1131
            +     +       K+E E Q     L++   Q       +R+     +++L E +D+ +
Sbjct: 1154 EAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQ 1213

Query: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS-- 1189
              + K EK+K +   EL+ + + +E  + + A  +++    E +    +  L+E  RS  
Sbjct: 1214 RVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLN 1273

Query: 1190 ----------------------HEAQVQEMRQ---KHAQAVEELTEQLEQFKRAKANL-- 1222
                                   EA + ++ +    + Q +E+L  QLE+  +AK  L  
Sbjct: 1274 DFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAH 1333

Query: 1223 ---------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKK 1255
                     D  ++  E+E    A   RVL +A  EV                  E  KK
Sbjct: 1334 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 1393

Query: 1256 KL-------EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
            KL       E  V+ + +KCS  E+ +  L +++  L  +VE         + K     K
Sbjct: 1394 KLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 1453

Query: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1368
             +A    + +++Q  L+   ++  ++ST+L +L+       + L+      +NL+  IS 
Sbjct: 1454 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 1513

Query: 1369 LNIQLSDSKKKLQDFASTVEALE--------------------EGK-KRFQKEIENLTQQ 1407
            L  QL +  K + +     + LE                    EGK  R Q E   +  +
Sbjct: 1514 LTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAE 1573

Query: 1408 YEEKAAAYDK-LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
             E K A  D+ +E+ K   Q+ +D L   LD + +  + + + ++K +  L  E  I   
Sbjct: 1574 IERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDL-NEMEIQLS 1632

Query: 1467 YADERDRAEAEAREKETKAL--SLARALEEALEAKEEL-------ERTNKMLKAEMEDLV 1517
            +A+ R  AEA+ + K  ++L       L++A+ A ++L       ER N +L+AE+E+L 
Sbjct: 1633 HAN-RMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELR 1691

Query: 1518 SSKD--------------DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQ------- 1556
            +  +              +  + V  L     +L  Q ++M++ L +L+ E++       
Sbjct: 1692 AVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECR 1751

Query: 1557 -ATEDAKLRL-EVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRAL 1614
             A E AK  + +  M A + + E+D  A  E+    ++ +++ + + +  L DE +Q AL
Sbjct: 1752 NAEEKAKKAITDAAMMAEELKKEQDTSAHLER---MKKNMEQTIKDLQHRL-DEAEQIAL 1807

Query: 1615 AAAAKK--KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD--FQRELEDARASRDE 1670
                K+  KLE  +++LE + ++  K   E++K +RK + ++K+  +Q E +     R +
Sbjct: 1808 KGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQ 1867

Query: 1671 IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDE 1730
                  + + KA   +A+  + Q +   ++  + Q +L++ E   ++A S    N L+ +
Sbjct: 1868 DLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQV--NKLRAK 1925

Query: 1731 KRRLEARIAQLEEE 1744
             R + A+    +EE
Sbjct: 1926 SRDIGAKQKMHDEE 1939


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 1424 bits (3687), Expect = 0.0
 Identities = 781/1913 (40%), Positives = 1186/1913 (61%), Gaps = 32/1913 (1%)

Query: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
            AK  V+V   K+ +  A ++  +G +V  +  E G  VTV +D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVVDPKESYVKAIVQSREGGKVTAK-TEAGATVTVKEDQVFSMNPPKYDKIEDMA 92

Query: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAP 152

Query: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+   +
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPAS 212

Query: 212  GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
            G+    LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLE
Sbjct: 213  GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 272

Query: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
            KSR   Q + ER++HIFY +++  K ++   LL+     ++ F+S G + +P+  D E  
Sbjct: 273  KSRVTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEEL 332

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
              T  A+ I+GF+ +E+++I K+  +V+  GN+ FK+++  +QA       A K  +L  
Sbjct: 333  MATDSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTS 392

Query: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
            +N  D  +S+  PR+KVG + V K QT +Q   AV ALAKA YE++F W++TR+N+ LD 
Sbjct: 393  LNSADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLD- 451

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 512  EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568

Query: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
            PK  K K E  FS++HYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+    
Sbjct: 569  PKPAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGA- 627

Query: 624  RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
                  Q A+          K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN 
Sbjct: 628  ------QTAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681

Query: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
             K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 682  TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741

Query: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
             K+A   ++ ++E+D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA+CRG+L 
Sbjct: 742  SKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLM 801

Query: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
            R  F K  ++  ++  IQ N  A++ +++W W +L+ K+KPLL+    E+EM   ++E +
Sbjct: 802  RVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861

Query: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
            KTKE   K E + KELE+K   L +EKN LQ Q+QAE +  A+AEE   +L   K +LE 
Sbjct: 862  KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEA 921

Query: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
             + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K 
Sbjct: 922  KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981

Query: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
            L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +LE  
Sbjct: 982  LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGS 1041

Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
            L++E+K   +LE+ KRKLEGD     E   D +    +L  +L KKE E+     +++DE
Sbjct: 1042 LEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDE 1101

Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
             A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T
Sbjct: 1102 QALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161

Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
            + Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKL 1221

Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
            +K K  L+ E  DLA  +  + +AK   E   + LE Q+ E+++K  + +R   EL+ + 
Sbjct: 1222 EKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQK 1281

Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
             +L  E    +  L+E +    +L++   + + Q+++ +  L+EET+ K  ++  L+   
Sbjct: 1282 ARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSAR 1341

Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
             + + L++Q +EE EAK  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1342 HDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401

Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
            ++  +  E   +    LEKTK RLQ E++DL++D++        L+KKQR FD++LAE K
Sbjct: 1402 QDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWK 1461

Query: 1462 NISSKYADERDRAEAEAREKETKALS-----LARALEEALEAKEELERTNKMLKAEMEDL 1516
                KY  E  +AE EA +KE+++LS     +  A EE+L+  E L+R NK L+ E+ DL
Sbjct: 1462 ---QKY--EETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDL 1516

Query: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
                 + GK++HELEK K+ L+ +  E++T LEE E  L+  E   LR+++ +  +K + 
Sbjct: 1517 TEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI 1576

Query: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA 1636
            +R +  +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A
Sbjct: 1577 DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHA 1636

Query: 1637 IKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
             +   EA++ LR  Q  +KD Q  L+DA   +D++       E++A  ++A++ +L+  L
Sbjct: 1637 NRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASL 1696

Query: 1697 AAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMS 1756
               ER RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         
Sbjct: 1697 ERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAE 1756

Query: 1757 DRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTI 1816
            ++ +KA   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  I
Sbjct: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1816

Query: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
              LEA++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  
Sbjct: 1817 QKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1876

Query: 1877 ARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
             +VK  KRQ EEAEE+S    A  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1877 TKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929



 Score = 74.7 bits (182), Expect = 8e-13
 Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)

Query: 849  RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEE 908
            +++ E    E E+Q     +Q AE  L+ L      L + +  L + ++ + +L  +   
Sbjct: 1619 KKKMEGDLNEMEIQLNHANRQAAE-ALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAM 1677

Query: 909  MRVRLAAKKQELEEILHEMEA-----RLEEEE-----DRGQQLQAERKKMAQQMLDLEEQ 958
            +  R    + E+EE+   +E      ++ E+E     +R Q L  +   +      LE  
Sbjct: 1678 VERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737

Query: 959  LEEEEAARQKLQLEKVTAEAKIKK-------LEDEILVMDDQNNKLSKERKLLEERISDL 1011
            + + +   + +  E   AE K KK       + +E+    D +  L + +K +E+ + DL
Sbjct: 1738 ISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1797

Query: 1012 TTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 1070
               L E E+ A K   K   K E+ + ELE  ++ E+K   E  K  RK E    +   Q
Sbjct: 1798 QLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQ 1857

Query: 1071 IADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
              + +  I  L+  + K + +++A   + ++   Q N  L K R+L+  + + +E  D  
Sbjct: 1858 TEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIA 1917

Query: 1131 RAARNKAEKQKRDL 1144
             +  NK   + R++
Sbjct: 1918 ESQVNKLRVKSREV 1931



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 64/273 (23%), Positives = 122/273 (44%), Gaps = 16/273 (5%)

Query: 844  LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
            L  V R+   MQA+ +EL+ + ER ++     K  EQ+    +E   LL  Q    T L 
Sbjct: 1675 LAMVERRANLMQAEVEELRASLERTERGR---KMAEQELLDASERVQLLHTQ---NTSLI 1728

Query: 904  AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
               +++   ++  + E+E+I+ E        E++ ++   +   MA+++   +EQ     
Sbjct: 1729 NTKKKLETDISQIQGEMEDIVQEAR----NAEEKAKKAITDAAMMAEELK--KEQDTSAH 1782

Query: 964  AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
              R K  +E+   + +++  E E L +     ++ K    LE R+ +L + +  E++   
Sbjct: 1783 LERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK----LEARVRELESEVESEQKHNV 1838

Query: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
               K   KHE  + EL  + +++ K+   L+ L  KL+     +  Q  + + Q      
Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898

Query: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIREL 1116
            +  K + EL+ A  R D   +Q N    K RE+
Sbjct: 1899 KFRKLQHELEEAKERADIAESQVNKLRVKSREV 1931


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 1424 bits (3686), Expect = 0.0
 Identities = 780/1908 (40%), Positives = 1182/1908 (61%), Gaps = 25/1908 (1%)

Query: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
            AK   +V   K+ +    IK  +  +V VE  E+ + + V  +D+  MNPPKF ++EDMA
Sbjct: 34   AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92

Query: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
             LT LNE +VL+NL++RY S +IYTYSGLFCV VNPYK LP+Y+ ++V+ Y+GKKR E P
Sbjct: 93   MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152

Query: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHK--GKKDTS 209
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++     KKD+ 
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212

Query: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
            + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEKS
Sbjct: 213  MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272

Query: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQ 327
            R   Q + ER++HIFY +++  K ++  +LLL   N  +Y F+S G + + +  D E   
Sbjct: 273  RVTFQLKAERSYHIFYQILSNKKPEL-IELLLITTNPYDYPFISQGEILVASIDDAEELL 331

Query: 328  ETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGI 387
             T  A+ I+GF+ EE+  + K+  +V+  GN+ FK+++  +QA       A K  +LMG+
Sbjct: 332  ATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGL 391

Query: 388  NVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-K 446
            N +D  +++  PR+KVG + V K QT +Q   AV AL+K+ YE+LF W++TR+N+ LD K
Sbjct: 392  NSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTK 451

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
              RQ   F+G+LDIAGFEIFE NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452  LPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 509

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 510  TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 566

Query: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
            PK +K + E  FS+IHYAG VDY+ S WL KN DPLN+ V  L   SS++ +A L+    
Sbjct: 567  PKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATF- 625

Query: 624  RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
                        +S     +K K   F+TV  L++E L KLM+ LR T P+FVRCIIPN 
Sbjct: 626  -------ATADADSGKKKVAKKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNE 678

Query: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
             K  G ++  LVL QLRCNGVLEGIRICR+GFPNRI++ +F+QRY +L A+AIP+G F+D
Sbjct: 679  TKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFID 738

Query: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
             K+AC  ++ ++++D   Y+ G +K+FF+ G+L  LEE RD ++  +I   QA+CRG+L 
Sbjct: 739  SKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLM 798

Query: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
            R  F K  Q+  ++  IQ N  +++ +++W W +LF K+KPLL+    E+EM   ++E Q
Sbjct: 799  RVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 858

Query: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
            KTK+   K+E + KELE+K   L +EKN LQ Q+QAE+E   +AEE   +L   K +LE 
Sbjct: 859  KTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEA 918

Query: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
             + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K 
Sbjct: 919  KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 978

Query: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
            L +E+  +D+   KL++E+K L+E       +L  EE+K  +L K K+K E  + +LE  
Sbjct: 979  LTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS 1038

Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
            L++E+K R +LE+ KRKLEGD     E I DL+    +L  +L KK+ E     ++++DE
Sbjct: 1039 LEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDE 1098

Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
                    KKI+EL+  I +L+E++++ERA R K EKQ+ D   ELE L   LE+    T
Sbjct: 1099 QTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT 1158

Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
            +TQ EL  KRE E   L++ L+E T  HEA V  +R+KHA +V EL EQ++  +R K  L
Sbjct: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218

Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
            +K K   + E  DL+  +  + ++K  +E   + LE Q+ E + K  + +R+ +EL  + 
Sbjct: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 1278

Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
             +LQ E   ++  L E E    +L++   + + Q ++ +  L+EE + K  ++  L+   
Sbjct: 1279 SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSR 1338

Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
             + + L++Q +EE E K  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1339 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1398

Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
            ++  +Q E   A    LEKTK RLQ E++DL+VD++    L + L+KKQR FD++LAE K
Sbjct: 1399 QDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWK 1458

Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
                +   E + +  E+R   T+   L  A EEAL+  E ++R NK L+ E+ DL     
Sbjct: 1459 TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA 1518

Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
            + GK +HELEKS++ +E +  +++  LEE E  L+  E   LR+++ +  +K + +R + 
Sbjct: 1519 ENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIA 1578

Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
             +DE+ E+ +R  QR +   ++ L+ E + R  A   KKK+EGDL ++E+Q   A +   
Sbjct: 1579 EKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAA 1638

Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
            E +K LR +Q Q+KD Q  L+DA   ++++       E++A  L+A++ +L+  L   ER
Sbjct: 1639 ETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTER 1698

Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
            ARK A+ E  +  E +    +   +L   K++LE  + QL+ E+E+   +     ++ +K
Sbjct: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758

Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
            A   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K  I  LE 
Sbjct: 1759 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818

Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
            +I +LE ++E E ++   + K L++ ++++KE+  Q E++RK   + ++  +K   +VK 
Sbjct: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878

Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
             KRQ EEA+E++       RK Q EL+EA E  +    +VN L++K R
Sbjct: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926



 Score =  131 bits (330), Expect = 6e-30
 Identities = 124/538 (23%), Positives = 251/538 (46%), Gaps = 51/538 (9%)

Query: 850  QEEEMQAKEDELQKTKERQQ-KAENELKELEQKHSQLT--EEKNLLQEQLQAETELYAEA 906
            Q E + AK   L+KTK+R Q + E+ + ++E+ +S     ++K    +++ AE +   E 
Sbjct: 1404 QVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEE 1463

Query: 907  EEMRVRLAAKK-QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962
             +  +  + K+ + L   L +++   EE  D+ + ++ E K + Q++ DL EQ+ E    
Sbjct: 1464 SQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKT 1523

Query: 963  ----EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEE 1018
                E +R++++LEK   +  +++ E     ++ +  K+ + +  L +  S++   +AE+
Sbjct: 1524 IHELEKSRKQIELEKADIQLALEEAE---AALEHEEAKILRIQLELTQVKSEIDRKIAEK 1580

Query: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
            +E+   + +LK  ++  +  ++  L  E +SR E  +LK+K+EGD ++   Q++    Q 
Sbjct: 1581 DEE---IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQA 1637

Query: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERA------ 1132
            AE    L   + +L+     LDD +  + +  +++  +E   + LQ +++  RA      
Sbjct: 1638 AETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE 1697

Query: 1133 -ARNKAEKQ---------------------KRDLGEELEALKTELEDTLDSTATQQELRA 1170
             AR  AE++                     K+ L  +L  L++E+ED        +E   
Sbjct: 1698 RARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAK 1757

Query: 1171 KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK-QTL 1229
            K   +  ++ + L +E +   A ++ M++   Q V++L  +L++ ++      K + Q L
Sbjct: 1758 KAITDAAMMAEELKKE-QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816

Query: 1230 EKENADLAGELRVLGQAKQEVEHKK--KKLEAQVQELQSKCSDGERARAELNDKVHKLQN 1287
            E    +L  EL   G+ K+  E  K  +K E +V+EL  +  +  +    L D V KLQ 
Sbjct: 1817 ETRIRELEFELE--GEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQV 1874

Query: 1288 EVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345
            +V+S      EA+ +A            +L++ +E       Q   +  K R     R
Sbjct: 1875 KVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTRDFTSSR 1932



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 75/314 (23%), Positives = 138/314 (43%), Gaps = 21/314 (6%)

Query: 849  RQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL------ 902
            +++ E    E E+Q +   +Q AE  LK L     QL + +  L + L+ + +L      
Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAET-LKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAI 1674

Query: 903  --------YAEAEEMRVRLA----AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950
                     AE EE+R  L     A+K   +E+L   E R++    +   L   +KK+  
Sbjct: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQELLDSNE-RVQLLHTQNTSLIHTKKKLET 1733

Query: 951  QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 1010
             ++ L+ ++E+     +  + +   A      + +E+    D +  L + +K LE+ + D
Sbjct: 1734 DLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1793

Query: 1011 LTTNLAEEEEKA-KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
            L   L E E+ A K   K   K E+ I ELE  L+ E+K   E  K  RK E    +   
Sbjct: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853

Query: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
            Q  + +  +  L+  + K + ++++   + ++   Q N  L K R+ +  + + +E  D 
Sbjct: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913

Query: 1130 ERAARNKAEKQKRD 1143
              +  NK   + RD
Sbjct: 1914 AESQVNKLRAKTRD 1927


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1423 bits (3683), Expect = 0.0
 Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%)

Query: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
            AK  V+V   K+ F   +I+  +G +V V+  E G  +TV  D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92

Query: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152

Query: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212

Query: 209  -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
              I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLE
Sbjct: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272

Query: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
            KSR + Q + ER++HIFY + +  K ++   LL+     +Y F+S G + + +  D E  
Sbjct: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
              T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +L  
Sbjct: 333  MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392

Query: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
            +N  D  +++  PR+KVG + V K QT EQ   AV ALAKA YE++F W++ R+N+ LD 
Sbjct: 393  LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 512  TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568

Query: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
            PK +K K E  F++IHYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+    
Sbjct: 569  PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628

Query: 624  RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
               G     +          K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN 
Sbjct: 629  TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683

Query: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
             K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684  TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743

Query: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
             K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA CRG+LA
Sbjct: 744  SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803

Query: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
            R  + +  ++  A+  IQ N  +++ +++W W +LF K+KPLL+    E+EM   ++E Q
Sbjct: 804  RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863

Query: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
            K K+   K+E + KELE+K   L +EKN LQ Q+QAE E  A+AEE   +L   K +LE 
Sbjct: 864  KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923

Query: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
             + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K 
Sbjct: 924  KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983

Query: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
            L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +LE  
Sbjct: 984  LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043

Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
            L++E+K R +LE+ KRKLEGD     E I D++ +  +L  +L KKE E+    ++++DE
Sbjct: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103

Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
             A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163

Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
            + Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223

Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
            +K K  ++ E  DLA  +  + +AK  +E   + LE Q+ EL+SK  + +R   +L  + 
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283

Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
             +LQ E    +  L+E E    +L++   + + Q+++ +  L+EE + K  ++  L+   
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343

Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
             + + L++Q +EE E+K  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403

Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
            +   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++LAE K
Sbjct: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463

Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
                +   E + ++ EAR   T+   +  A EE+L+  E L+R NK L+ E+ DL     
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523

Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
            + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R + 
Sbjct: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583

Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
             +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +   
Sbjct: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643

Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
            EA++  R  Q  +KD Q  L+DA  S++++       E++A  L+A++ +L+  L   ER
Sbjct: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703

Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
            +RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         ++ +K
Sbjct: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763

Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
            A   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  I  LEA
Sbjct: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823

Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
            ++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+VK 
Sbjct: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883

Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
             KRQ EEAEE+S    A  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931



 Score =  235 bits (599), Expect = 4e-61
 Identities = 225/1025 (21%), Positives = 456/1025 (44%), Gaps = 121/1025 (11%)

Query: 836  RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
            +L  K+K + +    EEE+ A+   + +K ++   + + ++ +LE   +++ +EK+  + 
Sbjct: 920  QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 979

Query: 895  QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
            +++  TE  A  +E   +L  +K+ L+E   +    L+ EED+   L   + K+ QQ+ D
Sbjct: 980  KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039

Query: 955  LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
            LE  LE+E+  R  L+  K   E  +K  ++ I+ ++++  +L ++ K  E  IS+L + 
Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099

Query: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
            + +E+     L K   + ++ I ELE  ++ E  SR + EK +  L  +  +  E++ + 
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159

Query: 1075 Q-AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSERA 1132
              A  A+++M   K+E E Q     L++   Q       +R+     +++L E +D+ + 
Sbjct: 1160 GGATSAQIEMN-KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218

Query: 1133 ARNKAEKQKRDLGEELEALKTE-----------------LEDTLDSTATQQELRAKREQE 1175
             + K EK+K ++  E++ L +                  LED L    +++E + +   +
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278

Query: 1176 VTVLKKALDEETRSHEAQVQEM----------RQKHAQAVEELTEQLEQFKRAKANL--- 1222
            +T  +  L  E+     Q+ E           +Q   Q +EEL  QLE+  +AK  L   
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338

Query: 1223 --------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKKK 1256
                    D  ++  E+E    A   R L +A  EV                  E  KKK
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398

Query: 1257 L-------EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
            L       E  V+ + +KC+  E+ +  L ++V  L  +VE         + K     K 
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458

Query: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
            +A    + ++T   L+   ++  ++ T+L +++       DQL+      +NL++ IS L
Sbjct: 1459 LAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1518

Query: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
              Q+++  K++ +     + +E+ K   Q  +E      E +     +++   N+++ E+
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578

Query: 1430 DDLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL 1488
            D  + + D +  QL  N  +        L  E    +     + + E +  E E +    
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638

Query: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
             R   EAL      +   K  +  ++D + S++D+ + +  +E+    L+ ++EE++  L
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698

Query: 1549 EELE--------DELQATE-------------DAKLRLEVNMQALKGQFERDLQ-ARDEQ 1586
            E+ E        + L A+E             + K +LE ++  ++G+ E  LQ AR+ +
Sbjct: 1699 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAE 1758

Query: 1587 NEEKR----------------------RQLQRQLHEYETELE---DERKQRALAAAAKK- 1620
             + K+                       ++++ + +   +L+   DE +Q AL    K+ 
Sbjct: 1759 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1818

Query: 1621 -KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
             KLE  +++LE + +S  K   EA+K LRK + ++K+   + E+ R +   +     + +
Sbjct: 1819 QKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1878

Query: 1680 KKAKSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
             K KS   +A+  + Q +   A+  + Q +LE+ E   ++A S    N L+ + R +  +
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTK 1936

Query: 1738 IAQLE 1742
            +   E
Sbjct: 1937 VISEE 1941


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 1423 bits (3683), Expect = 0.0
 Identities = 779/1908 (40%), Positives = 1181/1908 (61%), Gaps = 20/1908 (1%)

Query: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
            AK  V+V   K+ F   +I+  +G +V V+  E G  +TV  D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92

Query: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152

Query: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDT--- 208
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+    
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212

Query: 209  -SITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
              I G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLE
Sbjct: 213  GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272

Query: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
            KSR + Q + ER++HIFY + +  K ++   LL+     +Y F+S G + + +  D E  
Sbjct: 273  KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
              T  A+ I+GF+ EE++SI K+  +V+  GN+ FK+++  +QA       A K  +L  
Sbjct: 333  MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392

Query: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
            +N  D  +++  PR+KVG + V K QT EQ   AV ALAKA YE++F W++ R+N+ LD 
Sbjct: 393  LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLD- 451

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 512  TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQK 568

Query: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
            PK +K K E  F++IHYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+    
Sbjct: 569  PKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFSGAQ 628

Query: 624  RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
               G     +          K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN 
Sbjct: 629  TAEG-----EGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 683

Query: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
             K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 684  TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 743

Query: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
             K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QA CRG+LA
Sbjct: 744  SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803

Query: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
            R  + +  ++  A+  IQ N  +++ +++W W +LF K+KPLL+    E+EM   ++E Q
Sbjct: 804  RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863

Query: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
            K K+   K+E + KELE+K   L +EKN LQ Q+QAE E  A+AEE   +L   K +LE 
Sbjct: 864  KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923

Query: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
             + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K 
Sbjct: 924  KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 983

Query: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
            L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +LE  
Sbjct: 984  LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1043

Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
            L++E+K R +LE+ KRKLEGD     E I D++ +  +L  +L KKE E+    ++++DE
Sbjct: 1044 LEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDE 1103

Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
             A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T
Sbjct: 1104 QALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1163

Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
            + Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L
Sbjct: 1164 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1223

Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
            +K K  ++ E  DLA  +  + +AK  +E   + LE Q+ EL+SK  + +R   +L  + 
Sbjct: 1224 EKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQR 1283

Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
             +LQ E    +  L+E E    +L++   + + Q+++ +  L+EE + K  ++  L+   
Sbjct: 1284 GRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSR 1343

Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
             + + L++Q +EE E+K  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1344 HDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1403

Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
            +   +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++LAE K
Sbjct: 1404 QAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWK 1463

Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
                +   E + ++ EAR   T+   +  A EE+L+  E L+R NK L+ E+ DL     
Sbjct: 1464 QKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1523

Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
            + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R + 
Sbjct: 1524 EGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1583

Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
             +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +   
Sbjct: 1584 EKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1643

Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
            EA++  R  Q  +KD Q  L+DA  S++++       E++A  L+A++ +L+  L   ER
Sbjct: 1644 EALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1703

Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
            +RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         ++ +K
Sbjct: 1704 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKK 1763

Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
            A   A  ++ EL  E+ T+   E  ++ +E+  K+L+ +L E E       K  I  LEA
Sbjct: 1764 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEA 1823

Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
            ++ +LE +VE E +    A K L++ ++++KE+  Q E++RK   + ++  +K  A+VK 
Sbjct: 1824 RVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1883

Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
             KRQ EEAEE+S    A  RKLQ EL+EA E  +    +VN L+ K R
Sbjct: 1884 YKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931



 Score =  235 bits (599), Expect = 4e-61
 Identities = 225/1025 (21%), Positives = 456/1025 (44%), Gaps = 121/1025 (11%)

Query: 836  RLFTKVKPLLQVTRQEEEMQAK-EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
            +L  K+K + +    EEE+ A+   + +K ++   + + ++ +LE   +++ +EK+  + 
Sbjct: 920  QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 979

Query: 895  QLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
            +++  TE  A  +E   +L  +K+ L+E   +    L+ EED+   L   + K+ QQ+ D
Sbjct: 980  KVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD 1039

Query: 955  LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
            LE  LE+E+  R  L+  K   E  +K  ++ I+ ++++  +L ++ K  E  IS+L + 
Sbjct: 1040 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSK 1099

Query: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
            + +E+     L K   + ++ I ELE  ++ E  SR + EK +  L  +  +  E++ + 
Sbjct: 1100 IEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1159

Query: 1075 Q-AQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGH-ISDLQEDLDSERA 1132
              A  A+++M   K+E E Q     L++   Q       +R+     +++L E +D+ + 
Sbjct: 1160 GGATSAQIEMN-KKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1218

Query: 1133 ARNKAEKQKRDLGEELEALKTE-----------------LEDTLDSTATQQELRAKREQE 1175
             + K EK+K ++  E++ L +                  LED L    +++E + +   +
Sbjct: 1219 VKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLIND 1278

Query: 1176 VTVLKKALDEETRSHEAQVQEM----------RQKHAQAVEELTEQLEQFKRAKANL--- 1222
            +T  +  L  E+     Q+ E           +Q   Q +EEL  QLE+  +AK  L   
Sbjct: 1279 LTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338

Query: 1223 --------DKNKQTLEKENADLAGELRVLGQAKQEV------------------EHKKKK 1256
                    D  ++  E+E    A   R L +A  EV                  E  KKK
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398

Query: 1257 L-------EAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
            L       E  V+ + +KC+  E+ +  L ++V  L  +VE         + K     K 
Sbjct: 1399 LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKI 1458

Query: 1310 VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTL 1369
            +A    + ++T   L+   ++  ++ T+L +++       DQL+      +NL++ IS L
Sbjct: 1459 LAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1518

Query: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 1429
              Q+++  K++ +     + +E+ K   Q  +E      E +     +++   N+++ E+
Sbjct: 1519 TEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1578

Query: 1430 DDLVVDLDNQ-RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSL 1488
            D  + + D +  QL  N  +        L  E    +     + + E +  E E +    
Sbjct: 1579 DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1638

Query: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQL 1548
             R   EAL      +   K  +  ++D + S++D+ + +  +E+    L+ ++EE++  L
Sbjct: 1639 NRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1698

Query: 1549 EELE--------DELQATE-------------DAKLRLEVNMQALKGQFERDLQ-ARDEQ 1586
            E+ E        + L A+E             + K +LE ++  ++G+ E  LQ AR+ +
Sbjct: 1699 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAE 1758

Query: 1587 NEEKR----------------------RQLQRQLHEYETELE---DERKQRALAAAAKK- 1620
             + K+                       ++++ + +   +L+   DE +Q AL    K+ 
Sbjct: 1759 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQI 1818

Query: 1621 -KLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENE 1679
             KLE  +++LE + +S  K   EA+K LRK + ++K+   + E+ R +   +     + +
Sbjct: 1819 QKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQ 1878

Query: 1680 KKAKSL--EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
             K KS   +A+  + Q +   A+  + Q +LE+ E   ++A S    N L+ + R +  +
Sbjct: 1879 AKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQV--NKLRVKSREVHTK 1936

Query: 1738 IAQLE 1742
            +   E
Sbjct: 1937 VISEE 1941


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 1420 bits (3676), Expect = 0.0
 Identities = 777/1908 (40%), Positives = 1186/1908 (62%), Gaps = 22/1908 (1%)

Query: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
            AK  V+V   K+ F  A+++  +G +V  +  E G  VTV  D +  MNPPK+ K+EDMA
Sbjct: 34   AKTSVFVVDPKESFVKATVQSREGGKVTAK-TEAGATVTVKDDQVFPMNPPKYDKIEDMA 92

Query: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y+ ++V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAP 152

Query: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSIT 211
            PHI++I+D AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + KK+   +
Sbjct: 153  PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTS 212

Query: 212  GE----LEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
            G+    LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLE
Sbjct: 213  GKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272

Query: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLE-GFNNYTFLSNGFVPIPAAQDDEMF 326
            KSR   Q + ER++HIFY +++  K  +   LL+     +Y F+S G + +P+  D E  
Sbjct: 273  KSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEEL 332

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
              T  A+ I+GF+ +E++SI K+  +V+  GN+ FK+++  +QA       A K  +L  
Sbjct: 333  MATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQN 392

Query: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
            +N  D  +++  PR+KVG + V K QT +Q   AV ALAKA Y+++F W++TR+N+ LD 
Sbjct: 393  LNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLD- 451

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 452  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 512  TFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQK 568

Query: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
            PK  K K E  FS+IHYAG VDYN + WL KN DPLN+ V  L   S+ K +A L+    
Sbjct: 569  PKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLF---- 624

Query: 624  RIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNH 683
              VG    A+          K K   F+TV  L++E L KLMT LR+T P+FVRCIIPN 
Sbjct: 625  --VGATG-AEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNE 681

Query: 684  EKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMD 742
             K  G ++  LVL QLRCNGVLEGIRICR+GFP+RI++ +F+QRY++L A+AIP+G F+D
Sbjct: 682  TKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFID 741

Query: 743  GKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLA 802
             K+A   ++ ++++D   Y+ G +K+FF+ G+L  LEE RD K+  +I   QAMCRG+LA
Sbjct: 742  SKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLA 801

Query: 803  RKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQ 862
            R  + K  ++  ++  IQ N  A++ +++W W +L+ K+KPLL+    E+EM   ++E +
Sbjct: 802  RVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFE 861

Query: 863  KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEE 922
            KTKE   K E + KELE+K   L +EKN LQ Q+QAE +  A+AEE   +L   K +LE 
Sbjct: 862  KTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEA 921

Query: 923  ILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKK 982
             + E+  R E+EE+   +L A+++K+  +  +L++ +++ E    K++ EK   E K+K 
Sbjct: 922  KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981

Query: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042
            L +E+  +D+   KL+KE+K L+E       +L  EE+K   LTK K K E  + +LE  
Sbjct: 982  LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGS 1041

Query: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
            L++E+K R +LE+ KRKLEGD     E   D++    +L  +L KKE E+    ++++DE
Sbjct: 1042 LEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDE 1101

Query: 1103 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDST 1162
             A      KKI+EL+  I +L+E++++ERA+R KAEKQ+ DL  ELE +   LE+   +T
Sbjct: 1102 QALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGAT 1161

Query: 1163 ATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
            + Q E+  KRE E   +++ L+E T  HEA    +R+KHA +V EL EQ++  +R K  L
Sbjct: 1162 SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKL 1221

Query: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 1282
            +K K  ++ E  DLA  +  + +AK  +E   + LE Q+ E+++K  + +R   +L  + 
Sbjct: 1222 EKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQR 1281

Query: 1283 HKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLE 1342
             +LQ E    +  L+E +    +L++   + + Q+++ +  L+EE + K  ++  L+   
Sbjct: 1282 ARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSR 1341

Query: 1343 EERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEI 1401
             + + L++Q +EE EAK  L+R +S  N +++  + K + D     E LEE KK+  + +
Sbjct: 1342 HDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1401

Query: 1402 ENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
            ++  +  E   A    LEKTK RLQ E++DL++D++      + L+KKQR FD++LAE K
Sbjct: 1402 QDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWK 1461

Query: 1462 NISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKD 1521
                +   E + ++ E+R   T+   +  A EE+L+  E L+R NK L+ E+ DL     
Sbjct: 1462 QKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA 1521

Query: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
            + GK +HELEK K+ +E +  E++  LEE E  L+  E   LR+++ +  +K + +R + 
Sbjct: 1522 EGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIA 1581

Query: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGRE 1641
             +DE+ ++ +R   R +   ++ L+ E + R  A   KKK+EGDL ++E+Q + A +   
Sbjct: 1582 EKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAA 1641

Query: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
            EA++  R  QA +KD Q  L+DA  S++++       E++A  L+A++ +L+  L   ER
Sbjct: 1642 EALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTER 1701

Query: 1702 ARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRK 1761
            +RK A+ E  + +E +    +   +L + K++LE  I+Q++ E+E+         ++ +K
Sbjct: 1702 SRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKK 1761

Query: 1762 ATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEA 1821
            A   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K  I  LEA
Sbjct: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEA 1821

Query: 1822 KIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ 1881
            ++ +LE +VE E +    A K L++ ++K+KE+  Q E++RK   + ++  +K  A+VK 
Sbjct: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881

Query: 1882 LKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
             KRQ EEAEE+S    +  R++Q EL+EA E  +    +VN L+ K R
Sbjct: 1882 YKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 57/278 (20%), Positives = 122/278 (43%), Gaps = 12/278 (4%)

Query: 851  EEEMQAKED---ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
            ++ ++++ED   +L   + R    + E++EL     Q    + + +++L   +E      
Sbjct: 1662 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLH 1721

Query: 908  EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
                 L   K++LE  + +++  +E+     +  + + KK       + E+L++E+    
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781

Query: 968  KLQLEKVTAEAKIKKLEDEILVMDDQNNKLS-----KERKLLEERISDLTTNLAEEEEKA 1022
             L+  K   E  +K L+  +    D+  +L+     K+ + LE R+ +L   +  E+++ 
Sbjct: 1782 HLERMKKNLEQTVKDLQHRL----DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRN 1837

Query: 1023 KNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
                K   KHE  + EL  + +++ K+   L+ L  KL+     +  Q  + + Q     
Sbjct: 1838 VEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNL 1897

Query: 1083 MQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHI 1120
             +  + + EL+ A  R D   +Q N    K RE+   I
Sbjct: 1898 SKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKI 1935



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 68/292 (23%), Positives = 125/292 (42%), Gaps = 22/292 (7%)

Query: 861  LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 920
            L+ T+     A    ++L+++ + +    NLLQ          AE EE+R  L    ++ 
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQ----------AEIEELRATL----EQT 1699

Query: 921  EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 980
            E      E  L +  +R Q L  +   +      LE  + + +   + +  E   AE K 
Sbjct: 1700 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKA 1759

Query: 981  KK-------LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKA-KNLTKLKNKH 1032
            KK       + +E+    D +  L + +K LE+ + DL   L E E+ A K   K   K 
Sbjct: 1760 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1819

Query: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092
            E+ + ELE  ++ E+K   E  K  RK E    +   Q  + +  I  L+  + K + ++
Sbjct: 1820 EARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKV 1879

Query: 1093 QAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDL 1144
            ++   + ++   Q N  L K R ++  + + +E  D   +  NK   + R++
Sbjct: 1880 KSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREV 1931


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 1388 bits (3593), Expect = 0.0
 Identities = 782/1925 (40%), Positives = 1164/1925 (60%), Gaps = 31/1925 (1%)

Query: 30   WAAKRLVWVPSEKQGFEAASIKEEK-GDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVE 88
            W  K+ VWVP E+  +  A +K E  G  V VE  ++ K + V + ++Q MNPP+F  +E
Sbjct: 71   WDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVE-TKDQKVLMVREAELQPMNPPRFDLLE 129

Query: 89   DMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRH 148
            DMA +T LNEASVLHNLR+RY   +IYTYSGLFCV +NPYK LP+Y+  +V  YKGK+R 
Sbjct: 130  DMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRS 189

Query: 149  EMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS--SHKGKK 206
            + PPHIYA+AD AY  ML++R++QS+L TGESGAGKT NTK+VIQY A+VA+     GKK
Sbjct: 190  DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 249

Query: 207  D----TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
                 T   G LE Q+++ANP +EAFGNAKT++NDNSSRFGKFIRI+F  +G +  A+I+
Sbjct: 250  AQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADID 309

Query: 263  TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAA 320
            +YLLEKSR I Q   ER++H++Y +++G K +++ D+LL   N  +Y F S G + +   
Sbjct: 310  SYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQ-DMLLLSMNPYDYHFCSQGVITVDNM 368

Query: 321  QDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQK 380
             D E    T  AM I+GFS +E+ +  K+V ++L  GN+ FK+++  +QA      +A K
Sbjct: 369  NDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADK 428

Query: 381  VCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRV 440
              +LMG++  D  + +L PR++VG + V K Q+ EQ  FAV ALAKATY+RLFRW+++R+
Sbjct: 429  AAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRI 488

Query: 441  NKALD-KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 499
            N+ LD K  RQ   F+G+LDIAGFEIFE NSFEQLCIN+TNEKLQQ FN  MF+LEQEEY
Sbjct: 489  NQTLDTKLPRQ--FFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEY 546

Query: 500  QREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-G 558
            +REGI+W FIDFGLDLQPCI+LIE+P    G+L++L+EEC FPKA+D SF  KL     G
Sbjct: 547  KREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDNHAG 603

Query: 559  SHPKFQKP---KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFV 615
              P FQ+P   K+ K +  F ++HYAG V Y+   WL KN DPLN+ V  +   S ++ +
Sbjct: 604  KSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLL 663

Query: 616  ADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNF 675
            A L+++          +     S     + K   F+TV QL+KE L KLMT LR T P+F
Sbjct: 664  ATLYENY-----AGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHF 718

Query: 676  VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
            VRCI+PN  K  G +DAFLVL QLRCNGVLEGIRICRQGFPNR+++ +FRQRY IL  +A
Sbjct: 719  VRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSA 778

Query: 736  IPKG-FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQ 794
            IP   FMD ++A   ++ +L+LD   Y+ G +K+FF+ G+L  LEE RD ++  V+   Q
Sbjct: 779  IPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQ 838

Query: 795  AMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEM 854
            A  RG L R  + +      A+  IQ N  A+  ++NW W +LF K+KPLL+  + EEE+
Sbjct: 839  ARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEEL 898

Query: 855  QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLA 914
             A   EL+  +     AE + +ELE+ H  +T+EKN L  QLQAE +  A+AEE    L 
Sbjct: 899  AALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLI 958

Query: 915  AKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKV 974
              K +LE  + E+  RLE+EE+    L A R+K+  +  +L++ +++ +    K + EK 
Sbjct: 959  KSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQ 1018

Query: 975  TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034
              E K+K L +E+  +D+   +L+KE+K L+E       +L  EE++   LTK K + E 
Sbjct: 1019 ATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQ 1078

Query: 1035 MISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA 1094
             + +LE  L++E+K R + E+ KRKLEGD     E +AD      +L+ +L KK+ EL  
Sbjct: 1079 QVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQ 1138

Query: 1095 ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154
               R++DE        KKI+EL+    +L+E+L++ERAAR + EKQ+ +   ELE L   
Sbjct: 1139 LSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSER 1198

Query: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214
            LE+   ++A Q+E   KRE E+  L++ L+E    HEA V  +R+K A+   EL EQ++ 
Sbjct: 1199 LEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDS 1258

Query: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
             +R +  L+K K  L  E  DLA  +  L +AK   E   +  E Q+ E + K  + +R 
Sbjct: 1259 LQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ 1318

Query: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1334
             A+ + +  +LQ E   ++ +L E E    +L++  A  +  L++ +  L+EE++ K  +
Sbjct: 1319 LADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSAL 1378

Query: 1335 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEG 1393
            +  ++ L  + + L++Q +EE EA+  L+R +S  N +++  + K + D     E LEE 
Sbjct: 1379 AHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEA 1438

Query: 1394 KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453
            KK+    ++   +  E   A    LEK K RLQ E +D+ ++L+      + L+KKQR  
Sbjct: 1439 KKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHL 1498

Query: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513
            ++ L E +    +   E + A+ E+R   T+   L    EEALEA E L+R NK L+ E+
Sbjct: 1499 ERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEI 1558

Query: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALK 1573
             DL       GK++ ELEK+K+ALE +  E++  LEE E  L+  E   LR+++ +  +K
Sbjct: 1559 SDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1618

Query: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1633
             + +R L  +DE+    RR  QR +   +  L+ E + R  A   KKK+EGDL DLELQ 
Sbjct: 1619 AEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQL 1678

Query: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQ 1693
              A +   EA    R +QAQ+K+ Q   ++ +    E+   A+  E++A  L A+L +L+
Sbjct: 1679 GHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELR 1738

Query: 1694 EDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNME 1753
              L   ER+R+ A+ E  E  E L    S    L ++K++LEA +AQL  E+EE      
Sbjct: 1739 AALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERR 1798

Query: 1754 AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFK 1813
               ++ +KA   A  ++ EL  E+ T+   E  ++ LE+  +EL+++L E E A     K
Sbjct: 1799 EAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGK 1858

Query: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1873
              +  LEAK+ +LE +++ E ++   A K +++ ++++KE+  Q E++RK   + ++  +
Sbjct: 1859 KQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVD 1918

Query: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR---G 1930
            K  ++VK  KRQ EEAE+++    A  RK Q ELD+A E  +    + N L+++ R   G
Sbjct: 1919 KLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTRDALG 1978

Query: 1931 PPPQE 1935
            P  +E
Sbjct: 1979 PKHKE 1983


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 1387 bits (3591), Expect = 0.0
 Identities = 761/1918 (39%), Positives = 1167/1918 (60%), Gaps = 24/1918 (1%)

Query: 32   AKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMA 91
            +K+  +V   K+ +    I+  + D+V+V+ +++ + +T+  D +  MNPPKF K+EDMA
Sbjct: 34   SKKACFVADNKEMYVKGMIQTRENDKVIVKTLDD-RMLTLNNDQVFPMNPPKFDKIEDMA 92

Query: 92   ELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMP 151
             +T L+E +VL+NL+ERY + +IYTYSGLFCV VNPYK LP+Y  ++V  Y+GKKR E P
Sbjct: 93   MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAP 152

Query: 152  PHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS-- 209
            PHI++I+D AY+ ML DR++QSIL TGESGAGKT NTK+VIQY A +A +   KK+T   
Sbjct: 153  PHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKETQPG 212

Query: 210  -ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEK 268
             + G LE Q++QANP+LEAFGNAKTV+NDNSSRFGKFIRI+F  TG +  A+IETYLLEK
Sbjct: 213  KMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEK 272

Query: 269  SRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMF 326
            SR   Q   ER++HIFY +++  K ++  DLLL   N  ++ F+S G V + +  D E  
Sbjct: 273  SRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLISTNPFDFPFVSQGEVTVASIDDSEEL 331

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
              T  A+ I+GFS EE++ I K+  +V+  GN+ FK+++  +QA       A K  +LMG
Sbjct: 332  LATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMG 391

Query: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
            +N  +  + +  PR+KVG + V K Q  +Q   +V ALAKA YE++F W++TR+N+ LD 
Sbjct: 392  LNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLD- 450

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            T +    F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MF+LEQEEY++EGIEW
Sbjct: 451  TKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 510

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQK 565
             FIDFG+DL  CIELIE+P    G+ ++L+EEC FPKATD SF  KL  +  G    FQK
Sbjct: 511  EFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQK 567

Query: 566  PKQLKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVD 623
            PK  K K E  FS++HYAG VDYN + WL KN DPLN+ V  L   SS K ++ L+ +  
Sbjct: 568  PKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYA 627

Query: 624  RIVGLDQMAKMTESSLPSASKTKKGM-FRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPN 682
                    A+  +S        KKG  F+TV  +++E L KLMT LR+T P+FVRC+IPN
Sbjct: 628  G-------AETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRSTHPHFVRCLIPN 680

Query: 683  HEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FM 741
              K  G +D +LV+ QLRCNGVLEGIRICR+GFP+RI++ +F+QRY IL A+AIP+G F+
Sbjct: 681  ETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQFI 740

Query: 742  DGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYL 801
            D K A   ++ ++++D   +R G +K+FF+ G+L  LEE RD K+  ++ + QA+CRGYL
Sbjct: 741  DSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYL 800

Query: 802  ARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDEL 861
             R  F K  ++  ++  IQ N  +++ +++W W  LF K+KPLL+    E+EM   +++ 
Sbjct: 801  MRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDF 860

Query: 862  QKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELE 921
            ++TKE   ++E   KELE+K   L +EKN LQ Q+Q+ETE   +AEE    L   K  LE
Sbjct: 861  ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLE 920

Query: 922  EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIK 981
              + E+  RLEEEE+   +L A+++ +  +   L+  +++ E    K++ EK   E K+K
Sbjct: 921  AKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVK 980

Query: 982  KLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEV 1041
             L +E+  +++  +KL+KE+K L+E       +L  EE+K   L K+  K E    +LE 
Sbjct: 981  NLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEG 1040

Query: 1042 RLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDD 1101
             L++E+K R +LE+ KRKLEGD     E I DL+    +++ +L KKE EL    A++DD
Sbjct: 1041 SLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDD 1100

Query: 1102 EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDS 1161
            E        KKI+EL+  I +L+E++++E   R K EKQ+ DL  ELE +   LE+   +
Sbjct: 1101 EQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGA 1160

Query: 1162 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKAN 1221
            T+ Q E+  KRE E   +++ L+E T  HEA    +R+K A +V EL EQ++  +R K  
Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220

Query: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
            L+K K  L+ E  D+A  +  L ++K  +E   + +E Q  E+++K     +   +LN +
Sbjct: 1221 LEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280

Query: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
              +LQ +   ++  + E E    +L K   +L+ QL++ +  ++EET+ K  ++  L+  
Sbjct: 1281 KARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSS 1340

Query: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKE 1400
              + + L++Q +EE EAK  L+R +S  N +++  + K + D     E LEE KK+  + 
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400

Query: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
            ++   +  E   +    LEKTK RLQ E++DL+ DL+      + L+KKQR FD++LAE 
Sbjct: 1401 LQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEW 1460

Query: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSK 1520
            K    +   E + A+ E+R   T+   +  A EE ++  E L R NK L+ E+ DL    
Sbjct: 1461 KQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQI 1520

Query: 1521 DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDL 1580
             + GKN+ E EK+K+ +E +  +++  LEE+E  L+  E   LR+++ +  +K + +R +
Sbjct: 1521 AETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKV 1580

Query: 1581 QARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGR 1640
              +DE+ E+ +R  QR     ++ L+ E + R  A   KKK+EGDL ++E+Q   + +  
Sbjct: 1581 IEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQM 1640

Query: 1641 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAE 1700
             E  K LR +Q Q+KD Q  L+DA  S +++       E++   L  +L +++  L   E
Sbjct: 1641 AETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTE 1700

Query: 1701 RARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
            R R+ ++ E  + ++ +    S   +L + K++LEA IAQ + E+E          ++ +
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760

Query: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
            KA   A  ++ EL  E+ T+   E  ++ LE+  K+L+ +L E E       K  I  LE
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820

Query: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
             ++ +LE +++ E +    A K   + ++K+KE+  Q E++ K   + ++  +K  A+VK
Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880

Query: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQETSQ 1938
              KRQ EEAEE++    +  R++Q EL+EA E  +    +VN L++K R    Q+  +
Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 1241 bits (3212), Expect = 0.0
 Identities = 708/1907 (37%), Positives = 1109/1907 (58%), Gaps = 30/1907 (1%)

Query: 33   KRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAE 92
            K+  W+P  +  +  A +K  + D  V+    +G+ +++ +D IQ+MNPP+F  +EDMA 
Sbjct: 51   KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110

Query: 93   LTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPP 152
            LT LNEASVLH L+ RY   +IYTYSGLFCV +NPYK LP+Y ++++  YKGK+R E PP
Sbjct: 111  LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170

Query: 153  HIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITG 212
            HI+A+A+ A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+  + +K     G
Sbjct: 171  HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQ---G 227

Query: 213  ELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAI 272
             LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F   G +   +I+ YLLEKSR I
Sbjct: 228  ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287

Query: 273  RQARDERTFHIFYYMIAGAKEKMRSDLLLEGFN--NYTFLSNGFVPIPAAQDDEMFQETV 330
             Q   ER +HIFY +++G KE    DLLL   N  ++ F S G V + +  D E    T 
Sbjct: 288  FQQAGERNYHIFYQILSGQKEL--HDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATE 345

Query: 331  EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVT 390
            +AM I+GF  +E+    K+  +++  GN+ FK++   +Q        A K   LMGIN +
Sbjct: 346  QAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSS 405

Query: 391  DFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD-KTHR 449
            +  + ++ PRIKVG + V + QT EQ   AV AL+K+ YER+F+W++ R+N+ALD K  R
Sbjct: 406  ELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSR 465

Query: 450  QGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFI 509
            Q   F+GILDI GFEI E NS EQLCIN+TNEKLQQ FN  MF+LEQEEY++E IEW  I
Sbjct: 466  Q--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSI 523

Query: 510  DFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQ-GSHPKFQKPKQ 568
             FGLDLQ CI+LIE+P    G+L++L+EEC FPKATD +F  KL     G     QKPK 
Sbjct: 524  GFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKP 580

Query: 569  LKDKTE--FSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626
             K K E  F ++HYAG V YN S WL KN D LN+ V ++   SS++ +A L+++     
Sbjct: 581  DKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLFENY---- 636

Query: 627  GLDQMAKMTESSLPSASKTKK--GMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHE 684
                    T+S++P   K +K    F+TV  L+KE L KLMT L++T P+FVRCI PN  
Sbjct: 637  ------MSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVN 690

Query: 685  KRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-FMDG 743
            K  G LD +LVL+QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL     PK  F+  
Sbjct: 691  KIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSS 750

Query: 744  KQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLAR 803
            ++A   ++ +LE+D   YR G +K+FF+ G L  LE  RD +++ V   FQA  +G L R
Sbjct: 751  RKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMR 810

Query: 804  KAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQK 863
              F K  ++  A+ +IQ N  A++ ++NW W RLF K+KPL++ +   EE+   ++E  +
Sbjct: 811  IKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQ 870

Query: 864  TKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEI 923
             ++  +K+E + +EL+ K   LT+EKN L  QLQAE E  A  EE    L   K +LE  
Sbjct: 871  LQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEAR 930

Query: 924  LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKL 983
            + E+  R+EEEE+   +L A  +K+  +  +L++++++ E    K + EK T E K+K L
Sbjct: 931  VKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNL 990

Query: 984  EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRL 1043
             +E+  +++  +KL++  K+++E       +L  EEEK  +L+K   K E  + ELE  L
Sbjct: 991  TEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGAL 1050

Query: 1044 KKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI 1103
            ++E K+R   E+   KLEG+     E + +L++    L  +L KKE EL    +++++E 
Sbjct: 1051 EQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEK 1110

Query: 1104 AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTA 1163
                   K ++EL+  I DL+E L++ER  R K E+++ DL ++L  L   LE+   S+ 
Sbjct: 1111 GLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSL 1170

Query: 1164 TQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223
             Q E+  K+E +   L + ++E T   E     ++++HA ++ EL  Q+E  ++ K  L+
Sbjct: 1171 AQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLE 1230

Query: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283
            K+K  L+ E  DL   +  + +AK   E      E ++ E  +K     +   +L  +  
Sbjct: 1231 KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKT 1290

Query: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343
            KL +E       L E E    +L+++ ++ + Q++D +  L++ET+ +  ++  L++ + 
Sbjct: 1291 KLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQR 1350

Query: 1344 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQ-DFASTVEALEEGKKRFQKEIE 1402
            + + L++Q +EE E K  L R +S +N ++   + K + +     E LE+ KK     ++
Sbjct: 1351 DCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQ 1410

Query: 1403 NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN 1462
               +      A    LE+ +++LQ EL D + DL   R   + L++KQ +  + LA+ K 
Sbjct: 1411 EAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQ 1470

Query: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1522
               +     D ++ E +   T+ L L    EE++  +E L R NK L+ E+ +L +   +
Sbjct: 1471 KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVRE 1530

Query: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1582
              KN+ E+EK K+ +E +  E++  LEE E  L+  E   L  ++ +   K + ER L  
Sbjct: 1531 GTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSE 1590

Query: 1583 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642
            +DE+ E  RR+ Q  +   ++ L+ E K R      KKK+E DL ++ELQ   A +   E
Sbjct: 1591 KDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSE 1650

Query: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
            A K L +LQ Q+KD Q +L+D+     ++       E++   L+++L  L+      ER 
Sbjct: 1651 ATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERG 1710

Query: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
            R+ ++ E  E  E +    +   +L  +K++LEA +A++++E EE     +   ++ +KA
Sbjct: 1711 RRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKA 1770

Query: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAK 1822
              +A  LS EL  ++ T    E  R+ +E+   +L+ +L E E       +  I  LE++
Sbjct: 1771 AIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESR 1830

Query: 1823 IAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
            + +LE ++E E R    A +  ++ ++ +KE+  Q E+++K   + + Q +K   +V+  
Sbjct: 1831 VRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNY 1890

Query: 1883 KRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
            K+Q+E AE ++ +  +  +K Q EL+E  E  E    +VN LK K R
Sbjct: 1891 KQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937



 Score =  114 bits (285), Expect = 9e-25
 Identities = 100/469 (21%), Positives = 207/469 (44%), Gaps = 6/469 (1%)

Query: 851  EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
            ++E+QA   EL K K   +++    + L +++  L EE + L  Q++  T+   E E+++
Sbjct: 1483 QKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVK 1542

Query: 911  VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQ 970
              +  +K E++  L E E  LE  E +    Q E   + +   +LE +L E++   +  +
Sbjct: 1543 KLIEEEKTEVQVTLEETEGALERNESKILHFQLE---LLEAKAELERKLSEKDEEIENFR 1599

Query: 971  LEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKN 1030
             ++   +  I  L+  +        ++++ +K +EE ++++   L+    +    TK   
Sbjct: 1600 RKQ---QCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLG 1656

Query: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
            + +  I +L+++L    +   +L++     E   S    ++ DL++   + +      EE
Sbjct: 1657 QLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEE 1716

Query: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
            EL  A  R++    Q  + L + ++LE  ++ +Q++ +        AE++ +    E   
Sbjct: 1717 ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAAN 1776

Query: 1151 LKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTE 1210
            L  EL+   D+ A  +  R   EQ +T L+K L E  +      ++  QK    V EL  
Sbjct: 1777 LSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEG 1836

Query: 1211 QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD 1270
            +LE   R  A   +  + LE+   +L  +     +    ++ +  KL+ +VQ  + +   
Sbjct: 1837 ELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEV 1896

Query: 1271 GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319
             E    +   K  K Q+E+  V      AE +  KL         ++Q+
Sbjct: 1897 AETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAREFGKKVQE 1945



 Score =  111 bits (278), Expect = 6e-24
 Identities = 110/542 (20%), Positives = 225/542 (41%), Gaps = 61/542 (11%)

Query: 858  EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917
            ED  ++   R Q+A   +     +++ L   ++ LQ +L        +      RL  K+
Sbjct: 1399 EDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQ 1458

Query: 918  QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977
             +  + L + + + EE +      Q E + ++ ++L L+   EE    ++ L+ E    +
Sbjct: 1459 LQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQ 1518

Query: 978  AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE------------------ 1019
             +I  L +++        ++ K +KL+EE  +++   L E E                  
Sbjct: 1519 EEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELL 1578

Query: 1020 -----------EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFH 1068
                       EK + +   + K +  I  L+  L  E KSR E+ +LK+K+E D ++  
Sbjct: 1579 EAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEME 1638

Query: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLD 1128
             Q++    Q++E    L + + +++    +LDD     ++  +++   E   S LQ +L+
Sbjct: 1639 LQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELE 1698

Query: 1129 SERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETR 1188
              R+ + + E+ +R L EE E L+      L  T     L  K++ E  V +   + E  
Sbjct: 1699 DLRSLQEQTERGRR-LSEE-ELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEV 1756

Query: 1189 SHEAQ-VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--------------------- 1226
              E Q  +E  +K A     L+E+L++ +   A+L++ +                     
Sbjct: 1757 VQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMA 1816

Query: 1227 --------QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
                    Q LE    +L GEL    +   E +   ++LE  ++EL  +  + ++  + +
Sbjct: 1817 LMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRM 1876

Query: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
              ++ KLQ +V++    +  AE +A +          +L + +E  +    Q   +  K 
Sbjct: 1877 QTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKA 1936

Query: 1339 RQ 1340
            R+
Sbjct: 1937 RE 1938



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 27/137 (19%), Positives = 65/137 (47%), Gaps = 3/137 (2%)

Query: 850  QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
            ++  +     ++QK + R ++ E EL+   ++ ++       L+  ++   EL  +AEE 
Sbjct: 1813 EQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIK---ELTYQAEED 1869

Query: 910  RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
            +  L+  + +++++  +++   ++ E    Q      K  +Q  +L E  E  E A  ++
Sbjct: 1870 KKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQV 1929

Query: 970  QLEKVTAEAKIKKLEDE 986
               K+ A    KK+++E
Sbjct: 1930 NKLKIKAREFGKKVQEE 1946


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  607 bits (1565), Expect = e-173
 Identities = 439/1419 (30%), Positives = 719/1419 (50%), Gaps = 139/1419 (9%)

Query: 36   VWVPSEKQGFEAASIKEEK--GDEVVVELVENGKKV--TVGKDDIQKM-NPPKFSKVEDM 90
            VW+P  ++ +++A I ++   GD+V+  L+E+G ++  +V  + +  + NP       D+
Sbjct: 13   VWIPDPEEVWKSAEIAKDYRVGDKVLRLLLEDGTELDYSVNPESLPPLRNPDILVGENDL 72

Query: 91   AELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHE 149
              L+ L+E +VLHNLR R+  S LIYTYSG+  V +NPYK LPIY + I+  Y G+   +
Sbjct: 73   TALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQNMGD 132

Query: 150  MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
            M PHI+A+A+ AY+ M ++  +QSI+ +GESGAGKT + +  ++Y A V+ S        
Sbjct: 133  MDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN----- 187

Query: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
                +E ++L +NPI EA GNAKT +NDNSSRFGK+  I+FD    I+GAN+ TYLLEKS
Sbjct: 188  --AHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKS 245

Query: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLL---EGFNNYTFLSNGFVPIPAAQDDEMF 326
            R + Q+ +ER +HIFY + A A++     L L   E F NYT +    V I    D    
Sbjct: 246  RVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEF-NYTRMGGNTV-IEGVNDRAEM 303

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386
             ET +   ++GF E+ Q+ + K+++++L LGN+      N   +   D++  +  C L+G
Sbjct: 304  VETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLG 363

Query: 387  INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446
            +      + +   +I    + V K  T+ QA  A +ALAK  Y  LF +I+ R+N+AL  
Sbjct: 364  LESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQF 423

Query: 447  THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506
            + +Q  +F+G+LDI GFE F+VNSFEQ CINY NEKLQQ FN  +F LEQEEY +E I W
Sbjct: 424  SGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482

Query: 507  NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTE-QGSHPKFQK 565
              IDF  D QP I+LIE      G+L LLDEEC  P  TD+++++KL       +P F+K
Sbjct: 483  TLIDF-YDNQPVIDLIEA---KMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEK 538

Query: 566  PKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
            P+     T F I H+A KV+Y    +L KN D + D +  +L AS     A+ +++ +  
Sbjct: 539  PRM--SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQE-NPT 595

Query: 626  VGLDQMAKMTESSLPSASKTKKGMFR-TVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHE 684
                  + +T  S     K     FR TVG  ++  L  LM TL  TTP++VRCI PN E
Sbjct: 596  PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655

Query: 685  KRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGK 744
            K   + D+  +++QLR  GVLE IRI  Q +P+R  + EF  RY IL        F D K
Sbjct: 656  KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSFSDKK 714

Query: 745  QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARK 804
            + C +++  L  D N Y+ G++KIFFR G +A+LE+ R  K+    +  Q   RG+L RK
Sbjct: 715  EVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRK 774

Query: 805  AFAKRQQ-----------QLTAMK--------------VIQRNCAAYLKLRNWQWWRLFT 839
             F + ++           Q T  K              +IQ++C  YL    +Q  R+ T
Sbjct: 775  KFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMAT 834

Query: 840  KVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAE 899
                   +T Q                R   A    +++ ++H  +     +LQ+  +A 
Sbjct: 835  -------ITMQ-------------AYSRGFLARRRYRKMLEEHKAV-----ILQKYARA- 868

Query: 900  TELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL 959
                A      +R      +L   +  ++ +LE++      L  +   +A       E++
Sbjct: 869  --WLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKI 926

Query: 960  EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
            ++ EA  +K    +   E K K+  D +   +++  KL K    LE +   +   L E+ 
Sbjct: 927  QKLEAELEKAATHRRNYEEKGKRYRDAV---EEKLAKLQKHNSELETQKEQIQLKLQEKT 983

Query: 1020 EKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIA 1079
            E      +LK K +++  +L   ++KEE+ R  LEK     E    D+ +QI  L+ +I 
Sbjct: 984  E------ELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLKEEIK 1034

Query: 1080 EL---KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQ-EDLDSERAARN 1135
             L   KMQL    E        L  E+A+ +  +K I E E  I  LQ + +D E+    
Sbjct: 1035 ALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK---- 1090

Query: 1136 KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAK------REQEVTVLKKALDEETRS 1189
              + QKR++ E++  +  +L ++ D    +  L  +       + E+    + L + TR 
Sbjct: 1091 HVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRV 1150

Query: 1190 HEAQVQEMRQKHAQAVE-------ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV 1242
             E+  Q  +  + + +E        L++++   ++     +   +++  E   L  E  +
Sbjct: 1151 LESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHEVTRLTSENMM 1210

Query: 1243 LGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
            +   KQ++     +LE Q Q+L+ +          LN++  K++ ++E ++  L+ ++  
Sbjct: 1211 IPDFKQQI----SELEKQKQDLEIR----------LNEQAEKMKGKLEELSNQLHRSQ-- 1254

Query: 1303 AIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNL 1362
                 ++  +    L+   E+    T++K  +  K+++++E  + L+ Q + E E K N 
Sbjct: 1255 -----EEEGTQRKALEAQNEI---HTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNF 1306

Query: 1363 ERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI 1401
             +  S L ++  D +++L      ++ L++  K   K I
Sbjct: 1307 RQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTI 1345



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 107/479 (22%), Positives = 221/479 (46%), Gaps = 60/479 (12%)

Query: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSD----GERARAE 1277
            L K  +   KEN  L  +L  L   +     K +KLEA++++  +   +    G+R R  
Sbjct: 894  LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953

Query: 1278 LNDKVHKLQ---NEVESVTGMLN-EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL- 1332
            + +K+ KLQ   +E+E+    +  + + K  +L + + +L+ QL D    +Q+E RQ++ 
Sbjct: 954  VEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDD---VQKEERQRML 1010

Query: 1333 ---NVSTKLRQLEEERNSLQDQL----DEEMEAKQNLE-RHISTLNIQ-----LSDSKKK 1379
               +   K +  E++  SL++++    DE+M+ +  +E  H+++  ++     LS   K 
Sbjct: 1011 LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKT 1070

Query: 1380 LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ-ELDDLVVDLDN 1438
            + +F   +E L+  K   +K +++  ++  EK +     E TK  L+  +++D+      
Sbjct: 1071 ISEFEKEIELLQAQKIDVEKHVQSQKREMREKMS-----EITKQLLESYDIEDV-----R 1120

Query: 1439 QRQLVSNLEKKQRKFDQLLAEE------KNISSKYADERDRAEAEAREKETKALSLARAL 1492
             R  V +LE      +   A E      + + S +  ++D  E E      K + L++ +
Sbjct: 1121 SRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEI 1180

Query: 1493 EEALEAKEELERTNKMLKAEMEDLVSSK---DDVGKNVHELEKSKRALET----QMEEMK 1545
                +   E    N+ ++ E+  L S      D  + + ELEK K+ LE     Q E+MK
Sbjct: 1181 NHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMK 1240

Query: 1546 TQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETEL 1605
             +LEEL ++L  +++ +           G   + L+A++E + +++ +L  ++ E +   
Sbjct: 1241 GKLEELSNQLHRSQEEE-----------GTQRKALEAQNEIHTKEKEKLIDKIQEMQEAS 1289

Query: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
            +  +KQ    +  K     +   L L+     +  +   + ++KLQ Q+K   + +  A
Sbjct: 1290 DHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKA 1348



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 94/482 (19%), Positives = 208/482 (43%), Gaps = 51/482 (10%)

Query: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKML 1509
            +R+F  +     NI   Y  +R + + E + KE   L        AL A + +E+  K L
Sbjct: 872  RRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGD-VEKIQK-L 929

Query: 1510 KAEMEDLVSSK-----------DDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
            +AE+E   + +           D V + + +L+K    LETQ E+++ +L+E  +EL+  
Sbjct: 930  EAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKE- 988

Query: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
                      M  L  Q   D+Q  + Q     +  + +  +YE +++  +++       
Sbjct: 989  ---------KMDNLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDE 1039

Query: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
            K +L+  ++   + +D    G +  + +L K    + +F++E+E  +A + ++    +  
Sbjct: 1040 KMQLQHLVEGEHVTSD----GLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQ 1095

Query: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
            +++ +   +++ +   +    E  R +  +E  E   E          L+   R LE+  
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHF 1155

Query: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN---- 1794
               ++  E+E   +EA++ +V   +Q+   L      E      NES R ++ R      
Sbjct: 1156 QSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDI---NESIRHEVTRLTSENM 1209

Query: 1795 -----KELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
                 K+  S+L + +  ++ +       ++ K+ +L  Q+ +   E+    K+L+ +++
Sbjct: 1210 MIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNE 1269

Query: 1850 KLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE---EAEEESQRINANRRKLQRE 1906
                  +  +++ K+ ++ +E  E  +   KQ + + E      +E+ R+    R L+ E
Sbjct: 1270 ------IHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEE 1323

Query: 1907 LD 1908
            LD
Sbjct: 1324 LD 1325



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 106/476 (22%), Positives = 205/476 (43%), Gaps = 77/476 (16%)

Query: 1340 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
            QL      LQ +L+++ +    L   +++L    +   +K+Q   + +E     ++ +++
Sbjct: 886  QLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEE 945

Query: 1400 EIENLTQQYEEKAAAYDK--------LEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQ 1450
            + +      EEK A   K         E+ + +LQ++ ++L   +DN  +QL  +++K++
Sbjct: 946  KGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEE 1005

Query: 1451 RKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLAR-ALEEALEA--------KEE 1501
            R   Q +  EK+   K  D     + ++ ++E KAL   +  L+  +E         K E
Sbjct: 1006 R---QRMLLEKSFELKTQDY--EKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAE 1060

Query: 1502 LERTNKMLKA------EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE----- 1550
            + R +K +K       E+E L + K DV K+V   +  KR +  +M E+  QL E     
Sbjct: 1061 VARLSKQVKTISEFEKEIELLQAQKIDVEKHV---QSQKREMREKMSEITKQLLESYDIE 1117

Query: 1551 -------LEDELQATEDAKL------------RLEVNMQALKGQFERDLQARDEQNEEKR 1591
                   +ED     ED +L             LE + Q+ K  +E++++A + +     
Sbjct: 1118 DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLS 1177

Query: 1592 RQLQ--RQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQ-ADSAIKGREEAI 1644
            +++   ++L   E ++ +  +       ++  +  D K    +LE Q  D  I+  E+A 
Sbjct: 1178 QEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAE 1237

Query: 1645 KQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704
            K   KL+       R  E+    R  + A   +NE   K  E  + ++QE   A++  +K
Sbjct: 1238 KMKGKLEELSNQLHRSQEEEGTQRKALEA---QNEIHTKEKEKLIDKIQEMQEASDHLKK 1294

Query: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
            Q + E E                + E  RL      LEEEL+ +   ++ + D+V+
Sbjct: 1295 QFETESEVKCN-----------FRQEASRLTLENRDLEEELDMKDRVIKKLQDQVK 1339



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 14/172 (8%)

Query: 849  RQEEEMQAKEDELQ-KTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAE 907
            +Q  E++ ++ +L+ +  E+ +K + +L+EL  +  +  EE+   ++ L+A+ E++ + +
Sbjct: 1216 QQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEK 1275

Query: 908  EMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ 967
            E   +L  K QE++E    ++ + E E +     + E  ++  +  DLEE+L+ ++   +
Sbjct: 1276 E---KLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIK 1332

Query: 968  KLQLEKVTAEAKIKKLED--------EILVMDDQNNKLSKERKLLEERISDL 1011
            KLQ +  T    I K  D        E L M     K   E KL++  I DL
Sbjct: 1333 KLQDQVKTLSKTIGKANDVHSSSGPKEYLGM--LQYKREDEAKLIQNLILDL 1382



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 54/269 (20%), Positives = 125/269 (46%), Gaps = 23/269 (8%)

Query: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE--LA 1714
            +++ LE+ +A   + +A A    ++ +S+   ++ +Q         +K  D  KE   L 
Sbjct: 850  YRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLV 909

Query: 1715 EELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELA 1774
            E+L S  + R    ++ ++LEA + +        +   +   D V +   + ++ ++EL 
Sbjct: 910  EKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELE 969

Query: 1775 TERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA 1834
            T++      E  + +L+ + +EL+ K   M+   K  F   +   E +   LE+  E + 
Sbjct: 970  TQK------EQIQLKLQEKTEELKEK---MDNLTKQLFDD-VQKEERQRMLLEKSFELKT 1019

Query: 1835 REKQAATKSLKQKDKKLKEILLQ----VEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE 1890
            ++ +   +SLK++ K LK+  +Q    VE E   ++  K +  + + +VK +    +E E
Sbjct: 1020 QDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIE 1079

Query: 1891 -------EESQRINANRRKLQRELDEATE 1912
                   +  + + + +R+++ ++ E T+
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITK 1108


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score =  600 bits (1548), Expect = e-171
 Identities = 463/1688 (27%), Positives = 847/1688 (50%), Gaps = 180/1688 (10%)

Query: 26   AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
            A+  W     VW+   + GF  AS +K E+ +    +V V+L  +G  + V +DD++K N
Sbjct: 342  AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400

Query: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
             P   ++ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +YSEK++ 
Sbjct: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460

Query: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
            M+KG +R +M PHIYA+A TAYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520

Query: 201  SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
               G K  S+     ++      +LEAFGN+ T+ N N++RF + + ++FD  G +  A+
Sbjct: 521  I-SGNKVFSV-----EKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574

Query: 261  IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320
            I+T LLEK R  R+   E TF++FYY++A     +R++L L    N+   +N F  +P A
Sbjct: 575  IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630

Query: 321  QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RNTDQASMP 373
            + +E       F +   AM ++G S +EQ +   +++++  LG     KE     +    
Sbjct: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690

Query: 374  DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT----------------KEQA 417
             +  AQK  +L+G ++ + + +I   + K G   +Q++ +                K  A
Sbjct: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748

Query: 418  DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471
               +E +A   Y  LF  +++ VN+AL  +     S + I+D  GF+  E        SF
Sbjct: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807

Query: 472  EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------GLDLQPCI 519
            E+LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D                 Q  +
Sbjct: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867

Query: 520  ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQLKDKTEFS 576
              + R +   G+L LL+EE   P A++ + +E+L +  G      K Q P     K    
Sbjct: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927

Query: 577  II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624
            ++   H    V+YN + WL     +P   N   LL  S  K +++L+             
Sbjct: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987

Query: 625  IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
            I GL+  +++      S  KT   GM     +++    K Q+  L+ T++ +  +FV C 
Sbjct: 988  IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047

Query: 680  IPNHEKRSG-----------------------------KLDAFLVLEQLRCNGVLEGIRI 710
            +P  E  +G                             +LD  L+  QLR + +L+ +R+
Sbjct: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107

Query: 711  CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765
             RQG+P+ +VF EFR+R+++LA +   K       +D ++A   +++ L+L+ +   +G 
Sbjct: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167

Query: 766  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
            S++FFR G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ +Q+N   
Sbjct: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227

Query: 826  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-------L 878
               +++W WW+LFT V+PL++V   EE+++ K++E+Q+ + + +KAE E  E       L
Sbjct: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287

Query: 879  EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
            E + S+LT E  L  E+   E+       E   RL A+K E++E+  + +A  ++ E   
Sbjct: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344

Query: 939  QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995
             ++   R   A    ++  ++++++A  + +L+ E+   E     K+L+ E    +D+  
Sbjct: 1345 MEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLE 1398

Query: 996  KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052
               + ++ LE R+ DL    A+ EE  + L +LK K + + +EL+   + L+ ++    E
Sbjct: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455

Query: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110
            LEK +R+ + + S  HE     +AQ  +L+ +  ++E+++  A A  L  ++ +K+  + 
Sbjct: 1456 LEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510

Query: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
               +K+  LE  + D+      + A+  K +KQ RDL  +++  + EL++   +    ++
Sbjct: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570

Query: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
             + + E E+  +++   +E  S + +V+E RQ   + ++++  QLE+         ++KQ
Sbjct: 1571 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY-------EDKQ 1623

Query: 1228 TLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
             + +E  +L G+L  L  Q  +     +K+L   ++  ++  +D +     L +     +
Sbjct: 1624 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-K 1682

Query: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
             E+  +   L E+E       K   ++  +++D    + +  + K  +  +L +L+ E+N
Sbjct: 1683 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1742

Query: 1347 SLQDQLDEEMEAKQNL-ERHISTLN------IQLSDSKKKLQDFASTVEALEEGKKRFQK 1399
             +Q++L+E+ E    L ++H + +        Q++D + +L++     + L+E  +  Q 
Sbjct: 1743 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1802

Query: 1400 EIENLTQQYEEKAAA---YDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456
            ++E L Q   +K+       K+ + + RL+ E   +        +L  N+EK   + DQ 
Sbjct: 1803 QVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQR 1862

Query: 1457 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
            +A E    ++  ++  R + + R+ + +   LAR   EA   K ELE   + L+A  + L
Sbjct: 1863 IAAE----NREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918

Query: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
             +      K + +L+    A+E +ME      +E ED + + +D   + +     L+G  
Sbjct: 1919 QADLKLAFKRIGDLQ---AAIEDEMES-----DENEDLINSLQDMVTKYQKRKNKLEGDS 1970

Query: 1577 ERDLQARD 1584
            + D +  D
Sbjct: 1971 DVDSELED 1978



 Score =  231 bits (588), Expect = 7e-60
 Identities = 187/730 (25%), Positives = 367/730 (50%), Gaps = 60/730 (8%)

Query: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
            N+ KNK   +     L   +R L + +   E  + K E ++Q+L+SK    E+ R EL  
Sbjct: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282

Query: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
               +L++ +  +T  L +                   +   +LL  ET ++L    ++++
Sbjct: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328

Query: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379
            L+ + ++L+ Q++  EME  +      + +N ++ D                    +KK+
Sbjct: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388

Query: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
            LQ +F   +E  ++ K++ ++ + +L    EE   A  +L+K   RL  EL D  + L+ 
Sbjct: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448

Query: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
            Q+     LEKKQR+FD  L++    + +   +R++ + E      +A SL + LEE    
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508

Query: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
                 +    L+AE++D+ S +     ++ +++K  R LE ++++ + +L+E    +Q  
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568

Query: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
            E AKLRLE+ M+ ++    +++++RDE+ EE R+  Q++L + E +LE+E + +      
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628

Query: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
            K++LEG L  L   +D   +   E+ K+LRK    +K  +  L DA+   D +  +A   
Sbjct: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSAPSK 1682

Query: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
             + A+ L+  L + +   AAA +ARK  ++E E+L  ++      + AL+++  RL+   
Sbjct: 1683 REIAQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741

Query: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
             +++  LEE+Q +M  +  + + A  QA +   ++   ++  ++    +Q+L+ + + L+
Sbjct: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801

Query: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858
            S++  +E ++  K  S ++  EAKI +LE ++E E R +    +SL  + K+  E L + 
Sbjct: 1802 SQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858

Query: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913
             D+R  AE  +++  K      +L+RQL + +EE      +   A+R+K + E+D   ES
Sbjct: 1859 RDQRIAAENREKEQNK------RLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910

Query: 1914 NEAMGREVNA 1923
             EA  + + A
Sbjct: 1911 LEAANQSLQA 1920



 Score =  177 bits (450), Expect = 7e-44
 Identities = 202/870 (23%), Positives = 380/870 (43%), Gaps = 75/870 (8%)

Query: 955  LEEQLEEEEAARQKL---QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
            LEEQ +E+ +    L         A    KK + + L +      + K + + +     L
Sbjct: 1180 LEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL 1239

Query: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
             T +    E   +  +++NK E  I +L  +L+K EK R EL     +L  D        
Sbjct: 1240 FTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNEL-----RLNSDR------- 1286

Query: 1072 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1131
              L+++I+EL  +L  +    ++A   LD E A++  A K+++EL+     L++ +    
Sbjct: 1287 --LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM---- 1340

Query: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ---EVTVLKKALDEETR 1188
                  E  + ++ E       E+   +D      E R K E+   EV   KK L +E  
Sbjct: 1341 ------EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394

Query: 1189 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
                  Q+ +++  + + +L    E+ +RA   L K  Q L  E  D    L        
Sbjct: 1395 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454

Query: 1249 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
            E+E K+++ ++++ +   +    +  R +L  +   L  E  S+   L E +       +
Sbjct: 1455 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ 1514

Query: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1368
             V SL ++LQD      ++      V  +LR LE +    +++LDE+    Q LE+    
Sbjct: 1515 KVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLR 1574

Query: 1369 LNIQLSDSKKK-LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1427
            L +++   ++   ++  S  E +EE ++  QK+++ +  Q EE+     K+ + K  L+ 
Sbjct: 1575 LEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEG 1634

Query: 1428 ELDDLVVDLDNQRQLVSN--LEKKQRKFDQLLAEEK----NISSKYADERDRAEAEAREK 1481
            +L  L  D  N+R   S   L K  ++   LLA+ +    ++ +    +R+ A+ + + +
Sbjct: 1635 KLATLS-DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLE 1693

Query: 1482 ETK-----ALSLARALEEALE-----------AKEELERTNKMLKAEMEDLVSSKDDVGK 1525
            E++     A+   +A+E  +E           AK  LE     L+ E  ++ +  ++  +
Sbjct: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753

Query: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
            +++EL K  +A   Q      Q+ +L+ +L+     K  L+  +QAL+ Q E   Q+  +
Sbjct: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813

Query: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
            ++   R++ +  + E ET LE ER Q     +   +L+ +++ L  + D  I       +
Sbjct: 1814 KSLVSRQEAK--IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871

Query: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER---- 1701
            Q ++LQ Q++D + E+ +      E      E E   +SLEA    LQ DL  A +    
Sbjct: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGD 1931

Query: 1702 --ARKQADLEKEELAEELASSLSG--------RNALQ---DEKRRLEARIAQLEEELEEE 1748
              A  + ++E +E  E+L +SL          +N L+   D    LE R+  ++  L + 
Sbjct: 1932 LQAAIEDEMESDE-NEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKN 1990

Query: 1749 QGNMEAMSDRVRKATQQAEQLSNELATERS 1778
            +G  +A SD     +         LA +RS
Sbjct: 1991 KGPSKAASDDGSLKSSSPTSYWKSLAPDRS 2020



 Score =  120 bits (301), Expect = 1e-26
 Identities = 132/583 (22%), Positives = 263/583 (45%), Gaps = 60/583 (10%)

Query: 1384 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
            A T+  LEE  +R ++   NLT  ++     Y   +  K R  Q+L    V    Q+ + 
Sbjct: 1174 AGTLARLEE--QRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCV----QKNIK 1226

Query: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
             N   K   + +L    + +      E   +E + R K+ +   L   LE+A + + EL 
Sbjct: 1227 KNKGVKDWPWWKLFTTVRPLI-----EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281

Query: 1504 RTNKMLKAEMEDLVSSKDD---VGKNVHEL-----------EKSKRALETQMEEMKTQLE 1549
              +  L++ + +L S   D    G++  +L           EK  + L+TQ + +K Q+E
Sbjct: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME 1341

Query: 1550 ELEDELQAT--------------EDA----KLRLEVNMQAL---KGQFERDLQARDEQNE 1588
             +E E+                 +DA    +L+ E  ++ +   K + +++ + + E  +
Sbjct: 1342 VMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ 1401

Query: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLELQADSAIKGREEAIKQ 1646
            + +RQL+R+L + + + E+   QRAL    KK  +L  +L+D +L  +       E  K+
Sbjct: 1402 QNKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459

Query: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
             R+  +++     E +  +  R+++         +A SL+  L +   D+A   +     
Sbjct: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519

Query: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
            + E ++++ + +   +    ++ + R LEA++   EEEL+E+ G ++ +     +   + 
Sbjct: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579

Query: 1767 EQLSNELATE-RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825
            E++    + E  S  ++ E ARQ  +++ K++  +L E E   K K       LE K+A 
Sbjct: 1580 ERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLAT 1638

Query: 1826 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
            L +QV +   E +   K L++  K+ K +L    D + M +  K  A      + QLK Q
Sbjct: 1639 LSDQVNRRDFESE---KRLRKDLKRTKALL---ADAQLMLDHLKNSA-PSKREIAQLKNQ 1691

Query: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
            LEE+E         R+ ++ E+++     + + +   AL+ +L
Sbjct: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 67/317 (21%), Positives = 137/317 (43%), Gaps = 34/317 (10%)

Query: 1629 LELQ-ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1687
            +E+Q ++  I+ ++E I+QLR           +LE A   R+E+   +   E +   L +
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRS----------KLEKAEKERNELRLNSDRLESRISELTS 1296

Query: 1688 DLMQLQE---------DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
            +L   +          D   AER R  A+ E +EL  +  +       ++ E   +EAR+
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLR--AEKEMKELQTQYDALKKQMEVMEMEV--MEARL 1352

Query: 1739 ---AQLEEELEEEQGNME---AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
               A++  E++++    E        VR+     ++L  E   +    Q+N   ++QLER
Sbjct: 1353 IRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN---KRQLER 1409

Query: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
            +  +L++   E + A++ + K     L A++   +  +E +        K  ++ D +L 
Sbjct: 1410 RLGDLQADSEESQRALQ-QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELS 1468

Query: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATE 1912
            +   + + E+   E+ + + +   A    LK+QLEE + +          L+ EL + + 
Sbjct: 1469 QAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS 1528

Query: 1913 SNEAMGREVNALKSKLR 1929
                    +  +K +LR
Sbjct: 1529 QESKDEASLAKVKKQLR 1545



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 56/280 (20%), Positives = 130/280 (46%), Gaps = 21/280 (7%)

Query: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE---ELASSLS-----GRNALQ- 1728
            +E++ ++ + ++ QL+  L  AE+ R +  L  + L     EL S L+     G +A Q 
Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311

Query: 1729 -----DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ-QAEQLSNELATERSTAQ- 1781
                  E+ R E  + +L+ + +  +  ME M   V +A   +A +++ E+  + +  + 
Sbjct: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371

Query: 1782 --KNESARQQLERQNKELRSKLH---EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
              K E A ++++   K L+ +     E+E   K + +  +  L+A   + +  ++Q  ++
Sbjct: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKK 1431

Query: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896
             Q  T  L+     L+   ++  +  K   ++  +  + +   ++ K Q E+ + E   +
Sbjct: 1432 CQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDML 1491

Query: 1897 NANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQET 1936
             A    L+++L+E         ++V +L+++L+    QE+
Sbjct: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score =  598 bits (1543), Expect = e-170
 Identities = 462/1684 (27%), Positives = 838/1684 (49%), Gaps = 187/1684 (11%)

Query: 26   AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
            A+  W     VW+   + GF  AS +K E+ +    +V V+L  +G  + V +DD++K N
Sbjct: 342  AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400

Query: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
             P   ++ED+A L  LNE+SVLH LR+RY + L++TY+G   +V+ P     +YSEK++ 
Sbjct: 401  APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460

Query: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
            M+KG +R +M PHIYA+A TAYR+ML  R+DQSI+  G SG+GKT + + ++QYLA +A 
Sbjct: 461  MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520

Query: 201  SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
               G K  S+     ++      +LEAFGN+ T+ N N++RF + + ++FD  G +  A+
Sbjct: 521  I-SGNKVFSV-----EKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574

Query: 261  IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320
            I+T LLEK R  R+   E TF++FYY++A     +R++L L    N+   +N F  +P A
Sbjct: 575  IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630

Query: 321  QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RNTDQASMP 373
            + +E       F +   AM ++G S +EQ +   +++++  LG     KE     +    
Sbjct: 631  KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690

Query: 374  DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT----------------KEQA 417
             +  AQK  +L+G ++ + + +I   + K G   +Q++ +                K  A
Sbjct: 691  RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748

Query: 418  DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471
               +E +A   Y  LF  +++ VN+AL  +     S + I+D  GF+  E        SF
Sbjct: 749  LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807

Query: 472  EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------GLDLQPCI 519
            E+LC NYT ++LQ+LF+   F+ E E Y+ E IE  F D                 Q  +
Sbjct: 808  EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867

Query: 520  ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQLKDKTEFS 576
              + R +   G+L LL+EE   P A++ + +E+L +  G      K Q P     K    
Sbjct: 868  RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927

Query: 577  II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624
            ++   H    V+YN + WL     +P   N   LL  S  K +++L+             
Sbjct: 928  LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987

Query: 625  IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
            I GL+  +++      S  KT   GM     +++    K Q+  L+ T++ +  +FV C 
Sbjct: 988  IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047

Query: 680  IPNHEKRSG-----------------------------KLDAFLVLEQLRCNGVLEGIRI 710
            +P  E  +G                             +LD  L+  QLR + +L+ +R+
Sbjct: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107

Query: 711  CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765
             RQG+P+ +VF EFR+R+++LA +   K       +D ++A   +++ L+L+ +   +G 
Sbjct: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167

Query: 766  SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
            S++FFR G LA LEE+RD + +  +  FQA CRGYLAR+ F KR+ Q  A++ +Q+N   
Sbjct: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227

Query: 826  YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-------L 878
               +++W WW+LFT V+PL++V   EE+++ K++E+Q+ + + +KAE E  E       L
Sbjct: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287

Query: 879  EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
            E + S+LT E  L  E+   E+       E   RL A+K E++E+  + +A  ++ E   
Sbjct: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344

Query: 939  QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995
             ++   R   A    ++  ++++++A  + +L+ E+   E     K+L+ E    +D+  
Sbjct: 1345 MEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLE 1398

Query: 996  KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052
               + ++ LE R+ DL    A+ EE  + L +LK K + + +EL+   + L+ ++    E
Sbjct: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455

Query: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110
            LEK +R+ + + S  HE     +AQ  +L+ +  ++E+++  A A  L  ++ +K+  + 
Sbjct: 1456 LEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510

Query: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
               +K+  LE  + D+      + A+  K +KQ RDL  +++  + EL++   +    ++
Sbjct: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570

Query: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
             + + E E+  +++   +E  S + +V+E RQ   + ++++  QLE+         ++KQ
Sbjct: 1571 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY-------EDKQ 1623

Query: 1228 TLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
             + +E  +L G+L  L  Q  +     +K+L   ++  ++  +D +     L +     +
Sbjct: 1624 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-K 1682

Query: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
             E+  +   L E+E       K   ++  +++D    + +  + K  +  +L +L+ E+N
Sbjct: 1683 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1742

Query: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
             +Q++L+E+ E    L +       Q S    ++ D  + +E   + K+  Q++++ L  
Sbjct: 1743 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1802

Query: 1407 QYE-EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1465
            Q E  + +  DK     +R + ++ +L   L+ +R  V  LE        L +  K    
Sbjct: 1803 QVEFLEQSMVDK--SLVSRQEAKIRELETRLEFERTQVKRLE-------SLASRLKENME 1853

Query: 1466 KYADERD-RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
            K  +ERD R  AE REK               E  + L+R  +  K EM +L   + +  
Sbjct: 1854 KLTEERDQRIAAENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEAS 1898

Query: 1525 KNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
            +  HELE    +LE   + ++  L+   +   +LQA  + ++  + N   +  + + D+ 
Sbjct: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD 1958

Query: 1582 ARDE 1585
            +  E
Sbjct: 1959 SELE 1962



 Score =  231 bits (588), Expect = 7e-60
 Identities = 187/730 (25%), Positives = 367/730 (50%), Gaps = 60/730 (8%)

Query: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
            N+ KNK   +     L   +R L + +   E  + K E ++Q+L+SK    E+ R EL  
Sbjct: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282

Query: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
               +L++ +  +T  L +                   +   +LL  ET ++L    ++++
Sbjct: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328

Query: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379
            L+ + ++L+ Q++  EME  +      + +N ++ D                    +KK+
Sbjct: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388

Query: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
            LQ +F   +E  ++ K++ ++ + +L    EE   A  +L+K   RL  EL D  + L+ 
Sbjct: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448

Query: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
            Q+     LEKKQR+FD  L++    + +   +R++ + E      +A SL + LEE    
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508

Query: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
                 +    L+AE++D+ S +     ++ +++K  R LE ++++ + +L+E    +Q  
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568

Query: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
            E AKLRLE+ M+ ++    +++++RDE+ EE R+  Q++L + E +LE+E + +      
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628

Query: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
            K++LEG L  L   +D   +   E+ K+LRK    +K  +  L DA+   D +  +A   
Sbjct: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSAPSK 1682

Query: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
             + A+ L+  L + +   AAA +ARK  ++E E+L  ++      + AL+++  RL+   
Sbjct: 1683 REIAQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741

Query: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
             +++  LEE+Q +M  +  + + A  QA +   ++   ++  ++    +Q+L+ + + L+
Sbjct: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801

Query: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858
            S++  +E ++  K  S ++  EAKI +LE ++E E R +    +SL  + K+  E L + 
Sbjct: 1802 SQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858

Query: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913
             D+R  AE  +++  K      +L+RQL + +EE      +   A+R+K + E+D   ES
Sbjct: 1859 RDQRIAAENREKEQNK------RLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910

Query: 1914 NEAMGREVNA 1923
             EA  + + A
Sbjct: 1911 LEAANQSLQA 1920



 Score =  179 bits (455), Expect = 2e-44
 Identities = 197/856 (23%), Positives = 373/856 (43%), Gaps = 62/856 (7%)

Query: 955  LEEQLEEEEAARQKL---QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
            LEEQ +E+ +    L         A    KK + + L +      + K + + +     L
Sbjct: 1180 LEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL 1239

Query: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
             T +    E   +  +++NK E  I +L  +L+K EK R EL     +L  D        
Sbjct: 1240 FTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNEL-----RLNSDR------- 1286

Query: 1072 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1131
              L+++I+EL  +L  +    ++A   LD E A++  A K+++EL+     L++ +    
Sbjct: 1287 --LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM---- 1340

Query: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ---EVTVLKKALDEETR 1188
                  E  + ++ E       E+   +D      E R K E+   EV   KK L +E  
Sbjct: 1341 ------EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394

Query: 1189 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
                  Q+ +++  + + +L    E+ +RA   L K  Q L  E  D    L        
Sbjct: 1395 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454

Query: 1249 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
            E+E K+++ ++++ +   +    +  R +L  +   L  E  S+   L E +       +
Sbjct: 1455 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ 1514

Query: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1368
             V SL ++LQD      ++      V  +LR LE +    +++LDE+    Q LE+    
Sbjct: 1515 KVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLR 1574

Query: 1369 LNIQLSDSKKK-LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1427
            L +++   ++   ++  S  E +EE ++  QK+++ +  Q EE+     K+ + K  L+ 
Sbjct: 1575 LEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEG 1634

Query: 1428 ELDDLVVDLDNQRQLVSN--LEKKQRKFDQLLAEEK----NISSKYADERDRAEAEAREK 1481
            +L  L  D  N+R   S   L K  ++   LLA+ +    ++ +    +R+ A+ + + +
Sbjct: 1635 KLATLS-DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLE 1693

Query: 1482 ETK-----ALSLARALEEALE-----------AKEELERTNKMLKAEMEDLVSSKDDVGK 1525
            E++     A+   +A+E  +E           AK  LE     L+ E  ++ +  ++  +
Sbjct: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753

Query: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
            +++EL K  +A   Q      Q+ +L+ +L+     K  L+  +QAL+ Q E   Q+  +
Sbjct: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813

Query: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
            ++   R++ +  + E ET LE ER Q     +   +L+ +++ L  + D  I       +
Sbjct: 1814 KSLVSRQEAK--IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871

Query: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
            Q ++LQ Q++D + E+ +      E      E E   +SLEA    LQ DL  A   ++ 
Sbjct: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA--FKRI 1929

Query: 1706 ADLE---KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
             DL+   ++E+  +    L       D    LE R+  ++  L + +G  +A SD     
Sbjct: 1930 GDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLK 1989

Query: 1763 TQQAEQLSNELATERS 1778
            +         LA +RS
Sbjct: 1990 SSSPTSYWKSLAPDRS 2005



 Score =  161 bits (408), Expect = 5e-39
 Identities = 172/771 (22%), Positives = 348/771 (45%), Gaps = 83/771 (10%)

Query: 1069 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
            EQI +   +I +L+ +L K E+E   L+    RL+  I++  + L   R      S L  
Sbjct: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311

Query: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
             LD+E A R +AEK+ ++L  + +ALK ++E        + E+   R      +   +D+
Sbjct: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364

Query: 1186 ETRSHEAQVQEMRQKHAQAVEELT---EQLEQFKRAKANLDK-NKQTLEKENADLAGELR 1241
            +    E      R K+ +AV E+    ++L+Q    K  +++ NK+ LE+   DL  +  
Sbjct: 1365 DDAGGE-----WRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSE 1419

Query: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301
               +A Q+++ K ++L A++Q+ +      +    EL  K  +  +E+          + 
Sbjct: 1420 ESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKL 1479

Query: 1302 KAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQN 1361
            +  KL ++   L ++    ++ L+E+       + K+  LE E   +  Q  ++  +   
Sbjct: 1480 QREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539

Query: 1362 LERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK-LEK 1420
            +++ +  L  ++ D +++L + A T++ LE+ K R + E+E + Q + ++  + D+ +E+
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599

Query: 1421 TKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE 1480
             +   Q++L  + V L+ +       E KQ+    +L E++ +  K A   D+      E
Sbjct: 1600 ARQSCQKKLKQMEVQLEEE------YEDKQK----VLREKRELEGKLATLSDQVNRRDFE 1649

Query: 1481 KETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQ 1540
             E +              +++L+RT    KA + D     D +        K+    + +
Sbjct: 1650 SEKRL-------------RKDLKRT----KALLADAQLMLDHL--------KNSAPSKRE 1684

Query: 1541 MEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHE 1600
            + ++K QLEE E    A   A+  +EV ++ L  Q + D+       EE+  +LQR+ +E
Sbjct: 1685 IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID-DIAKAKTALEEQLSRLQREKNE 1743

Query: 1601 YETELEDE--------RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 1652
             +  LE++        +K +A  A A + L   + DL+ Q + A K ++E  ++L+ LQ+
Sbjct: 1744 IQNRLEEDQEDMNELMKKHKAAVAQASRDL-AQINDLQAQLEEANKEKQELQEKLQALQS 1802

Query: 1653 QMKDFQRELED-ARASRDEIFATAKENE--------KKAKSLEADLMQLQEDLAAAERAR 1703
            Q++  ++ + D +  SR E      E          K+ +SL + L +  E L      R
Sbjct: 1803 QVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQR 1862

Query: 1704 KQADLEKEELAEELASSLSGRNALQDEKRRLEARIA----QLEEELEEEQGNMEAMSDRV 1759
              A+  ++E  + L   L        E  R EA  +    +LE +LE  +   +++   +
Sbjct: 1863 IAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADL 1922

Query: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
            + A ++   L   +  E  + +  +    +    + ++ S+L +    VKS
Sbjct: 1923 KLAFKRIGDLQAAIEDEMESDENEDLINSE---GDSDVDSELEDRVDGVKS 1970



 Score =  120 bits (301), Expect = 1e-26
 Identities = 132/583 (22%), Positives = 263/583 (45%), Gaps = 60/583 (10%)

Query: 1384 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
            A T+  LEE  +R ++   NLT  ++     Y   +  K R  Q+L    V    Q+ + 
Sbjct: 1174 AGTLARLEE--QRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCV----QKNIK 1226

Query: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
             N   K   + +L    + +      E   +E + R K+ +   L   LE+A + + EL 
Sbjct: 1227 KNKGVKDWPWWKLFTTVRPLI-----EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281

Query: 1504 RTNKMLKAEMEDLVSSKDD---VGKNVHEL-----------EKSKRALETQMEEMKTQLE 1549
              +  L++ + +L S   D    G++  +L           EK  + L+TQ + +K Q+E
Sbjct: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME 1341

Query: 1550 ELEDELQAT--------------EDA----KLRLEVNMQAL---KGQFERDLQARDEQNE 1588
             +E E+                 +DA    +L+ E  ++ +   K + +++ + + E  +
Sbjct: 1342 VMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ 1401

Query: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLELQADSAIKGREEAIKQ 1646
            + +RQL+R+L + + + E+   QRAL    KK  +L  +L+D +L  +       E  K+
Sbjct: 1402 QNKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459

Query: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
             R+  +++     E +  +  R+++         +A SL+  L +   D+A   +     
Sbjct: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519

Query: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
            + E ++++ + +   +    ++ + R LEA++   EEEL+E+ G ++ +     +   + 
Sbjct: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579

Query: 1767 EQLSNELATE-RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825
            E++    + E  S  ++ E ARQ  +++ K++  +L E E   K K       LE K+A 
Sbjct: 1580 ERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLAT 1638

Query: 1826 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
            L +QV +   E +   K L++  K+ K +L    D + M +  K  A      + QLK Q
Sbjct: 1639 LSDQVNRRDFESE---KRLRKDLKRTKALL---ADAQLMLDHLKNSA-PSKREIAQLKNQ 1691

Query: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
            LEE+E         R+ ++ E+++     + + +   AL+ +L
Sbjct: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 67/317 (21%), Positives = 137/317 (43%), Gaps = 34/317 (10%)

Query: 1629 LELQ-ADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA 1687
            +E+Q ++  I+ ++E I+QLR           +LE A   R+E+   +   E +   L +
Sbjct: 1247 IEVQLSEEQIRNKDEEIQQLRS----------KLEKAEKERNELRLNSDRLESRISELTS 1296

Query: 1688 DLMQLQE---------DLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
            +L   +          D   AER R  A+ E +EL  +  +       ++ E   +EAR+
Sbjct: 1297 ELTDERNTGESASQLLDAETAERLR--AEKEMKELQTQYDALKKQMEVMEMEV--MEARL 1352

Query: 1739 ---AQLEEELEEEQGNME---AMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
               A++  E++++    E        VR+     ++L  E   +    Q+N   ++QLER
Sbjct: 1353 IRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN---KRQLER 1409

Query: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
            +  +L++   E + A++ + K     L A++   +  +E +        K  ++ D +L 
Sbjct: 1410 RLGDLQADSEESQRALQ-QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELS 1468

Query: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATE 1912
            +   + + E+   E+ + + +   A    LK+QLEE + +          L+ EL + + 
Sbjct: 1469 QAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISS 1528

Query: 1913 SNEAMGREVNALKSKLR 1929
                    +  +K +LR
Sbjct: 1529 QESKDEASLAKVKKQLR 1545



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 56/280 (20%), Positives = 130/280 (46%), Gaps = 21/280 (7%)

Query: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE---ELASSLS-----GRNALQ- 1728
            +E++ ++ + ++ QL+  L  AE+ R +  L  + L     EL S L+     G +A Q 
Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311

Query: 1729 -----DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ-QAEQLSNELATERSTAQ- 1781
                  E+ R E  + +L+ + +  +  ME M   V +A   +A +++ E+  + +  + 
Sbjct: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371

Query: 1782 --KNESARQQLERQNKELRSKLH---EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
              K E A ++++   K L+ +     E+E   K + +  +  L+A   + +  ++Q  ++
Sbjct: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKK 1431

Query: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896
             Q  T  L+     L+   ++  +  K   ++  +  + +   ++ K Q E+ + E   +
Sbjct: 1432 CQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDML 1491

Query: 1897 NANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQET 1936
             A    L+++L+E         ++V +L+++L+    QE+
Sbjct: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  598 bits (1542), Expect = e-170
 Identities = 463/1469 (31%), Positives = 743/1469 (50%), Gaps = 111/1469 (7%)

Query: 36   VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
            VW+P  ++ +++A + ++   GD+V++  +E GK +    D   K      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 89   DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
            D+  L+ L+E +VLHNLR R+  S LIYTY G+  V +NPY+ LPIY E I++ Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 148  HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
             +M PHI+A+A+ AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186

Query: 208  TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
             +    +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD    I+GAN+ TYLLE
Sbjct: 187  -ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245

Query: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDD-EMF 326
            KSR + QA +ER +HIFY + A AK      L L   +N+ +   G  P+    DD +  
Sbjct: 246  KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV-CHLM 385
              T +A  ++G SE  Q+ I ++++ +L LGN+ F   R+ D  ++P       + C LM
Sbjct: 306  AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364

Query: 386  GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
            G++  +    +   ++    +   K  +K QA  A +ALAK  Y +LF WI+  VN+AL 
Sbjct: 365  GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424

Query: 446  KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
               +Q  SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I 
Sbjct: 425  SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483

Query: 506  WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQGSHPKFQ 564
            W  IDF  D QPCI LIE   +  G+L LLDEEC  PK TD ++ +KL  T       F+
Sbjct: 484  WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539

Query: 565  KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
            KP+ L +K  F I H+A KV+Y    +L KN D + +    +L +S  K + +L++D ++
Sbjct: 540  KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 625  IVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTLRNTTPNF 675
             +          + L  + +K  KG          +TVG  ++  L  LM TL  TTP++
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 676  VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
            VRCI PN  K     D    ++QLR  GVLE IRI   GFP+R  +QEF  RY +L    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716

Query: 736  IPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 795
                  D KQ C  +++ L LD + Y+ G++KIFFR G +A+LE+ R  K+    +  Q 
Sbjct: 717  -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775

Query: 796  MCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLFTKVKPLL 845
              RG+L RK + + R+  +T  + +   Q  C A    R        ++WR++       
Sbjct: 776  TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY------- 828

Query: 846  QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
             V R+  +++     + ++  R   A N  +++ ++H  +  +K +     +   +    
Sbjct: 829  -VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 906  A---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLDLEEQLEE 961
            A    +   R    K+EL+++  ++EAR  E   R ++L      K+ Q    ++EQ ++
Sbjct: 888  AIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRKVDEQNKD 942

Query: 962  EEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDLTTNLAEE 1018
             +   +KL   +    ++ +KL  ++  L + ++  K++  R L L+E I+ L  +L + 
Sbjct: 943  YKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQT 1002

Query: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
              + K + +  ++++    +L   LK+E    +QE E L  ++   A +  E +      
Sbjct: 1003 RSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETM------ 1056

Query: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
              E K+    K+ EL      L+DE  +  N L +   LE    DL+E++          
Sbjct: 1057 --EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPG 1109

Query: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQE 1196
             K+      +      E E    S   + E    R +E +  K  LD       + +V E
Sbjct: 1110 HKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164

Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQEVEHKKK 1255
            + Q+     +EL  + EQ  R+KA         E+E   + G EL      +QE+E + K
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQELESENK 1216

Query: 1256 KLEAQVQELQSKCSDGERARAELN-DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLS 1314
            KL+ ++ EL+   S  E++  E+        +  +E +T +  E + +     ++V  L 
Sbjct: 1217 KLKNELNELRKALS--EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVR----KEEVLILR 1270

Query: 1315 SQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLS 1374
            SQL   +E +Q   +   N  T    L E+   ++D+  E  +A   L+     L  QL 
Sbjct: 1271 SQLVSQKEAIQ--PKDDKNTMTDSTILLEDVQKMKDK-GEIAQAYIGLKETNRLLESQLQ 1327

Query: 1375 DSKKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
              K+  ++ A      +++L+E   R Q+++     Q   +A     L+    RL  E  
Sbjct: 1328 SQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQNLQLPPEARIEASLQHEITRLTNENL 1386

Query: 1431 DLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
            DL+  L+ Q + V  L+K+ + F + + E
Sbjct: 1387 DLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415



 Score = 88.6 bits (218), Expect = 5e-17
 Identities = 144/665 (21%), Positives = 264/665 (39%), Gaps = 113/665 (16%)

Query: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
            AK+E+  KK K+EA+  E   K   G      + +K+ +LQ +V+               
Sbjct: 901  AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940

Query: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
              KD   L  +L + + +   ET +KL    +  QL EE            EAK    R 
Sbjct: 941  --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985

Query: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1424
            +S L  +++  +K L+   S  + +EE   R+++E E L     EE      + E   +R
Sbjct: 986  LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044

Query: 1425 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
            + Q+  ++   ++ +     +QL  +L  ++ ++  LL E   +  +Y D ++       
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104

Query: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1538
              +           ++  +  E E       AEMED+ S  ++  +    L+ S    L+
Sbjct: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159

Query: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
             ++ E++ + + ++DEL   E+  LR                    +  EE+R Q++   
Sbjct: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198

Query: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1656
                 ELE E  +R    +  KKL+ +L +L   L   SA +         R L  Q+  
Sbjct: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254

Query: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
               EL D R     I  +   ++K+A   + D   + +     E  +K  D  K E+A+ 
Sbjct: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311

Query: 1717 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE 1776
                      L++  R LE+++   +   E E                 AE L  E+   
Sbjct: 1312 YIG-------LKETNRLLESQLQSQKRSHENE-----------------AEALRGEI--- 1344

Query: 1777 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
              + ++  + +QQL  QN +L       E  +++  +  I  L  +   L EQ+E++ + 
Sbjct: 1345 -QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQDKT 1398

Query: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEEESQ 1894
             +   K LK   KK+ E+ +   +     +   E     N   + K  +  LE  +E+ Q
Sbjct: 1399 VRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1458

Query: 1895 RINAN 1899
            ++  N
Sbjct: 1459 KLVKN 1463



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 108/531 (20%), Positives = 220/531 (41%), Gaps = 65/531 (12%)

Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1252
            M ++  + ++     +E++K+    ++      ++ ++++N D    +  L   +     
Sbjct: 900  MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959

Query: 1253 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
            + +KL + ++ LQ    + + A      L +++ KL+ ++E         E  A +  ++
Sbjct: 960  ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019

Query: 1310 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1359
               L S L++   LL++E ++ LN            T  ++L EE   L+  L++E    
Sbjct: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078

Query: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1416
            QNL    S L  +  D K+++      V   + G KR      +   +Y    E A   D
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135

Query: 1417 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
               +T+   ++++  D+ + L  Q+++    ++KQ   D+L  +E+ +    A E +R +
Sbjct: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195

Query: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAE----------------MEDLVSS 1519
                E E ++L       E  + K EL    K L  +                ME L S 
Sbjct: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV 1255

Query: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
             +++     E+      L +Q+   K  ++  +D+   T+   L  +V     KG+  + 
Sbjct: 1256 SEELDVRKEEV----LILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQA 1311

Query: 1580 LQARDEQNE--EKRRQLQRQLHEYETEL----------EDERKQRALA--------AAAK 1619
                 E N   E + Q Q++ HE E E           E+ R+Q+ LA        A  +
Sbjct: 1312 YIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIE 1371

Query: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDE 1670
              L+ ++  L  +    ++  E+  K +RKL+ Q+K F +++ +    + E
Sbjct: 1372 ASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQME 1422



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 92/491 (18%), Positives = 198/491 (40%), Gaps = 56/491 (11%)

Query: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
            E  + + EAR  E           + ++ + +++  NK  K  +E L + +        +
Sbjct: 904  ELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEK 963

Query: 1530 LEKSKRALETQMEEMKT----------QLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
            L      L+   EE K           ++ +L  +L+ T   K  +E +    K + E+ 
Sbjct: 964  LRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023

Query: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
            +    E+N   +++ +   H    + ++      +    +KKL  + K LEL  +     
Sbjct: 1024 VSNLKEENTLLKQEKEALNHRIVQQAKE------MTETMEKKLVEETKQLELDLNDERLR 1077

Query: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
             +  + +  +L+ +  D + E+         +    K   K+  S  +      E + ++
Sbjct: 1078 YQNLLNEFSRLEERYDDLKEEMT-------LMVHVPKPGHKRTDSTHSS--NESEYIFSS 1128

Query: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
            E A  +    + E   E    L     L     +L+ R+ +LE+E +  Q  ++   ++V
Sbjct: 1129 EIAEMEDIPSRTEEPSEKKVPLDMSLFL-----KLQKRVTELEQEKQVMQDELDRKEEQV 1183

Query: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA- 1818
             ++  + E+       E    +     RQ+LE +NK+L+++L+E+  A+  K    + A 
Sbjct: 1184 LRSKAKEEERPQIRGAE---LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAP 1240

Query: 1819 -------LEAKIAQLEEQVEQEARE-------KQAATKSLKQKDKK--LKEILLQVEDER 1862
                   L  ++  + E+++    E         +  ++++ KD K  + +  + +ED +
Sbjct: 1241 GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ 1300

Query: 1863 KMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAMGREV 1921
            KM +  K +  +    +K+  R LE   +  +R + N  + L+ E+    E N    R+ 
Sbjct: 1301 KMKD--KGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEEN---NRQQ 1355

Query: 1922 NALKSKLRGPP 1932
              L   L+ PP
Sbjct: 1356 QLLAQNLQLPP 1366



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 92/354 (25%), Positives = 157/354 (44%), Gaps = 52/354 (14%)

Query: 1611 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-RKLQAQMKDFQ------RELED 1663
            +R +A    KKL+ + + +E      I G E  I QL RK+  Q KD++        LE 
Sbjct: 897  RRMMAKRELKKLKIEARSVERYKKLHI-GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG 955

Query: 1664 ARASRDEIFATAKE----NEKKAKSLEADLMQLQEDLAAAERARKQADLEK--------- 1710
               S  E   +  E    +E++AK     ++ LQE++A   +  +Q   EK         
Sbjct: 956  IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR 1015

Query: 1711 -EELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
             ++  E+L S+L   N  L+ EK  L  RI Q  +E+ E    ME      +K  ++ +Q
Sbjct: 1016 YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------KKLVEETKQ 1066

Query: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA---------L 1819
            L  +L  ER   Q   +   +LE +  +L+ ++  M    K   K T +           
Sbjct: 1067 LELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIF 1126

Query: 1820 EAKIAQLEE---QVEQEAREKQAATKSLKQK-DKKLKEI-----LLQVEDERKMAEQYKE 1870
             ++IA++E+   + E+ + +K     SL  K  K++ E+     ++Q E +RK  EQ   
Sbjct: 1127 SSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK-EEQVLR 1185

Query: 1871 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES-NEAMGREVNA 1923
               K   R +    +LE    + Q + +  +KL+ EL+E  ++ +E    EV A
Sbjct: 1186 SKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 9/147 (6%)

Query: 846  QVTRQEEEMQAKEDELQKTK-----ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET 900
            Q+  Q+E +Q K+D+   T      E  QK +++  E+ Q +  L E   LL+ QLQ++ 
Sbjct: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDK-GEIAQAYIGLKETNRLLESQLQSQK 1330

Query: 901  ELYA-EAEEMRVRLAAKKQE--LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEE 957
              +  EAE +R  + + K+E   ++ L     +L  E      LQ E  ++  + LDL E
Sbjct: 1331 RSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLME 1390

Query: 958  QLEEEEAARQKLQLEKVTAEAKIKKLE 984
            QLE+++   +KL+ +      KI +LE
Sbjct: 1391 QLEKQDKTVRKLKKQLKVFAKKIGELE 1417


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  596 bits (1537), Expect = e-170
 Identities = 462/1523 (30%), Positives = 751/1523 (49%), Gaps = 159/1523 (10%)

Query: 36   VWVPSEKQGFEAASI-KEEKGDEVVVELVENGKKVTVGKDDIQK------MNPPKFSKVE 88
            VW+P   + + +A + K+ K  +  ++L    + +     D+Q+       NP       
Sbjct: 13   VWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPDILVGEN 72

Query: 89   DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
            D+  L+ L+E +VLHNL+ R+  S  IYTY G+  V +NPY+ LPIY + ++  Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQNM 132

Query: 148  HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
             +M PHI+A+A+ AY+ M +D ++QSI+ +GESGAGKT + K  ++Y A V  S     +
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---ASE 189

Query: 208  TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
            T+I    E+++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD   +I+GAN+ TYLLE
Sbjct: 190  TNI----EEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLE 245

Query: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMF 326
            KSR + QA DER +HIFY + A A      +L L    ++ + S  G   I    D E F
Sbjct: 246  KSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDF 305

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM-PDNTAAQKVCHLM 385
            ++T +A  ++G  E  Q+SI K+++S+L LG++  + ER+ D  S+ P +      C L+
Sbjct: 306  EKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLL 365

Query: 386  GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
            G+  +     +   ++    +   K  + +Q   A  ALAK  Y +LF WI+  +NKAL 
Sbjct: 366  GVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALH 425

Query: 446  KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
             + +Q  SF+G+LDI GFE FEVNSFEQ CINY NEKLQQ FN  +F LEQEEY +E I 
Sbjct: 426  TSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484

Query: 506  WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQK 565
            W  IDF  D QPCI+LIE      G+L LLDEEC  PK TD+++ +KL     S   FQK
Sbjct: 485  WTLIDF-YDNQPCIDLIEA---KLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK 540

Query: 566  PKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRI 625
            P+     T F I+H+A KV+Y +  +L KN D + +   ++L AS    VADL+ D    
Sbjct: 541  PRM--SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598

Query: 626  V-----GLDQMAKMT-ESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
            V     G    +K++  S+ P    + K   +TVG  ++  L  LM TL  TTP++VRCI
Sbjct: 599  VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658

Query: 680  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739
             PN EK     D    ++QLR  GVLE IRI   G+P+R  + +F  RY +L        
Sbjct: 659  KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-ELA 717

Query: 740  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799
              D K  C  +++ L  DP+ ++ G++KIFFR G +A+LE+ R  K     +  Q   RG
Sbjct: 718  NTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRG 777

Query: 800  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 859
            +L +    K  +   A   +QR C  +L  R  +  R       L               
Sbjct: 778  WLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVL--------------- 819

Query: 860  ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 919
                                QKH ++   +   Q   +A   + A    M VR     + 
Sbjct: 820  --------------------QKHYRMQRARQAYQRVRRAAVVIQAFTRAMFVR-----RT 854

Query: 920  LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ--KLQLEKVTAE 977
              ++L E +A   ++  RG   +   +++    + ++      +A R+   L++E  +AE
Sbjct: 855  YRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAE 914

Query: 978  AKIKKL----EDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
              +K+L    E++++ +  + ++ +KE K L E++S  T+    E E+ K   +L +  +
Sbjct: 915  -HLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKK--ELVHYQQ 971

Query: 1034 SMISELEVRLKKE-EKSRQELEKL--KRKLEGDA-----SDFHEQIADLQAQIAELKMQL 1085
            S   +  +RL++E E  R EL++   +RK+  DA      +  +++ADL+ + A LK   
Sbjct: 972  SPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLK--- 1028

Query: 1086 AKKEEELQAALARLDDEIAQKN------------------NALKKIRELEGHISDLQEDL 1127
             +KE+     L +  DE AQ +                  N +K+  +LE    +L++++
Sbjct: 1029 DEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEM 1088

Query: 1128 ----DSERAARNKAEKQKRDLGEELEALKT-ELEDTLDSTATQQEL-RAKREQEVTVLKK 1181
                 +    RN + +   +      ++ T E+ DT D+    +E+   K   ++TV  K
Sbjct: 1089 TIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLK 1148

Query: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKE-NADLAGEL 1240
                     + +V+E+ Q+  +   +L E+ EQ    K   +  +  ++ + NADLA   
Sbjct: 1149 L--------QKRVRELEQERKKLQVQL-EKREQQDSKKVQAEPPQTDIDLDPNADLAYN- 1198

Query: 1241 RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
                  +QE+E + KKL+  + EL+   +D    +A  N+  H   +    +   L  A 
Sbjct: 1199 ---SLKRQELESENKKLKNDLNELRKAVAD----QATQNNSSHGSPDSYSLLLNQLKLAH 1251

Query: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
             +     ++V  L +Q+    +        + N++ +      E++  Q+   E      
Sbjct: 1252 EELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVC 1311

Query: 1361 NLERHISTLNIQLSDSK-----KKLQDFASTVEA-LEEGKKRFQKEIENLTQQYEEKAAA 1414
                          D +     + L+  A  +EA L+      ++E+E+L  Q E     
Sbjct: 1312 QTNSKTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEE 1371

Query: 1415 YDKLEKT-------------KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEK 1461
             DK ++T             +  +QQE+  L  +  + ++LV  LEK +RK    L ++ 
Sbjct: 1372 MDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERK----LKKQL 1427

Query: 1462 NISSKYADERDRAEAEAREKETK 1484
             I  K A + + A+A A+ +  +
Sbjct: 1428 KIYMKKAQDLEAAQALAQSERKR 1450



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 125/543 (23%), Positives = 240/543 (44%), Gaps = 69/543 (12%)

Query: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH-EAQ 1193
            NK  + +R + E+ +  KT  E    +T+T      + ++E+   +++  E+T    + +
Sbjct: 925  NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEE 984

Query: 1194 VQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL-----RVLGQAKQ 1248
            V+ +R +  +A  E     +   R K  L K    LE+ENA L  E      ++L Q+K 
Sbjct: 985  VESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD 1044

Query: 1249 EVEH---KKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM----LNEAEG 1301
            E      K+  ++ +++E +S+  +  +  ++L  +   L++E+  +        N +  
Sbjct: 1045 EFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQ 1104

Query: 1302 KAIKLAKDVASLS-SQLQDTQELLQ-------EETRQKLNVSTKL----RQLEEERNSLQ 1349
             +++   +  S+S S++ DT++ LQ       E+    + V  KL    R+LE+ER  LQ
Sbjct: 1105 SSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQ 1164

Query: 1350 DQLDE-EMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY 1408
             QL++ E +  + ++      +I L D    L   +   + LE   K+ + ++  L +  
Sbjct: 1165 VQLEKREQQDSKKVQAEPPQTDIDL-DPNADLAYNSLKRQELESENKKLKNDLNELRKAV 1223

Query: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
             ++A        T+N       D    L NQ +L    E + RK + L+   + +S   A
Sbjct: 1224 ADQA--------TQNNSSHGSPDSYSLLLNQLKLAHE-ELEVRKEEVLILRTQIVS---A 1271

Query: 1469 DERDRAEAEAREKETKALSLARA-----LEEALEAKEELERTNKMLKAEMEDLVSSKDDV 1523
            D+R  A   A        S   +      E+A+EA   + +TN   K E    ++   ++
Sbjct: 1272 DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS--KTEDWGYLNEDGEL 1329

Query: 1524 GKNVHELEKSKRALETQM-----------EEMKTQLEELEDELQATE-----------DA 1561
            G     L++  R LE Q+           E +K QLE L++E+   +           +A
Sbjct: 1330 GLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEA 1389

Query: 1562 KLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKK 1620
            ++   V  +  +   E  DL+   E+ E+  R+L++QL  Y  + +D    +ALA + +K
Sbjct: 1390 QVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERK 1449

Query: 1621 KLE 1623
            + E
Sbjct: 1450 RHE 1452



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 155/658 (23%), Positives = 265/658 (40%), Gaps = 110/658 (16%)

Query: 1239 ELRVLGQAKQEVEHKKKK---LEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295
            EL+ L    +  EH K+    +E +V +LQ K  +         +K  K  +E  SVT  
Sbjct: 902  ELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDE--------QNKEFKTLSEQLSVTTS 953

Query: 1296 LNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEE 1355
                E + +K  + V    S  +DT   LQEE     ++ T+L++   ER  L+D    E
Sbjct: 954  TYTMEVERLK-KELVHYQQSPGEDTSLRLQEEVE---SLRTELQRAHSERKILEDAHSRE 1009

Query: 1356 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEI--ENLTQ-QYEEKA 1412
             +  +     +   N  L D K++L +     + L + K  F +    ENL + + EE+ 
Sbjct: 1010 KDELRKRVADLEQENALLKDEKEQLNN-----QILCQSKDEFAQNSVKENLMKKELEEER 1064

Query: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1472
            + Y  L K  ++L+Q  D              NL  +     Q     +N S++ + E D
Sbjct: 1065 SRYQNLVKEYSQLEQRYD--------------NLRDEMTIIKQTPGHRRNPSNQSSLESD 1110

Query: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532
                     E          E+AL+  EE+     + KA M+  V  K  + K V ELE+
Sbjct: 1111 SNYPSISTSEIGDT------EDALQQVEEIG----LEKAAMDMTVFLK--LQKRVRELEQ 1158

Query: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
             ++ L+ Q+E+ + Q            D+K   +V  +  +   + D  A    N  KR+
Sbjct: 1159 ERKKLQVQLEKREQQ------------DSK---KVQAEPPQTDIDLDPNADLAYNSLKRQ 1203

Query: 1593 QLQRQLHEYETELEDERKQRALAAAAKKKLEGD-------LKDLELQADSAIKGREEAIK 1645
            +L+ +  + + +L + RK  A  A       G        L  L+L A   ++ R+E + 
Sbjct: 1204 ELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKL-AHEELEVRKEEVL 1262

Query: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
             LR  Q    D QR L    A  +    ++  N +K           QED   A     Q
Sbjct: 1263 ILRT-QIVSAD-QRRLAGRNAEPNINARSSWPNSEKHVD--------QEDAIEAYHGVCQ 1312

Query: 1706 ADLEKEELAE-----ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
             + + E+        EL  +  G   L+   R LEA++     E EEE  +++A  + ++
Sbjct: 1313 TNSKTEDWGYLNEDGELGLAYQG---LKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALK 1369

Query: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
            +   + +Q   +       AQ     +Q++ R   E                K  +  LE
Sbjct: 1370 EEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNE------------NLDLKELVEKLE 1417

Query: 1821 AKIAQLEEQVEQEAREKQ--AATKSLKQKDKKLKEILLQVEDERK------MAEQYKE 1870
                +L++Q++   ++ Q   A ++L Q ++K  E+  QV  +RK      M E +KE
Sbjct: 1418 KNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKE 1475



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 70/369 (18%), Positives = 157/369 (42%), Gaps = 43/369 (11%)

Query: 1475 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 1534
            +A   +K  +     R  +   +A   ++   +MLKA  E  + +     ++   L++  
Sbjct: 863  KATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRE--LKALRIEARSAEHLKRLN 920

Query: 1535 RALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD----LQARDEQNEEK 1590
              +E ++ +++ +++E   E +   +   +L V       + ER     +  +    E+ 
Sbjct: 921  VGMENKVVQLQRKIDEQNKEFKTLSE---QLSVTTSTYTMEVERLKKELVHYQQSPGEDT 977

Query: 1591 RRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLK----DLELQADSAIKGREEAIKQ 1646
              +LQ ++    TEL+    +R +   A  + + +L+    DLE Q ++ +K  +E +  
Sbjct: 978  SLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLE-QENALLKDEKEQLNN 1036

Query: 1647 LRKLQAQMKD-----------FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQED 1695
              ++  Q KD            ++ELE+ R+    +     + E++  +L  ++  +++ 
Sbjct: 1037 --QILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQT 1094

Query: 1696 LAAAERARKQADLEKEELAEELASSLSG--RNALQDEKR--------------RLEARIA 1739
                     Q+ LE +     +++S  G   +ALQ  +               +L+ R+ 
Sbjct: 1095 PGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVR 1154

Query: 1740 QLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRS 1799
            +LE+E ++ Q  +E    +  K  Q     ++      +    N   RQ+LE +NK+L++
Sbjct: 1155 ELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKN 1214

Query: 1800 KLHEMEGAV 1808
             L+E+  AV
Sbjct: 1215 DLNELRKAV 1223


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  596 bits (1536), Expect = e-170
 Identities = 464/1487 (31%), Positives = 745/1487 (50%), Gaps = 120/1487 (8%)

Query: 36   VWVPSEKQGFEAASIKEE--KGDEVVVELVENGKKVTVGKDDIQK-----MNPPKFSKVE 88
            VW+P  ++ +++A + ++   GD+V++  +E GK +    D   K      NP       
Sbjct: 13   VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72

Query: 89   DMAELTCLNEASVLHNLRERYF-SGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKR 147
            D+  L+ L+E +VLHNLR R+  S LIYTY G+  V +NPY+ LPIY E I++ Y G+  
Sbjct: 73   DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132

Query: 148  HEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKD 207
             +M PHI+A+A+ AY+ M +D  +QSI+ +GESGAGKT + K  ++Y A V+ S      
Sbjct: 133  GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186

Query: 208  TSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLE 267
             +    +E+++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD    I+GAN+ TYLLE
Sbjct: 187  -ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245

Query: 268  KSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDD-EMF 326
            KSR + QA +ER +HIFY + A AK      L L   +N+ +   G  P+    DD +  
Sbjct: 246  KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305

Query: 327  QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV-CHLM 385
              T +A  ++G SE  Q+ I ++++ +L LGN+ F   R+ D  ++P       + C LM
Sbjct: 306  AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364

Query: 386  GINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALD 445
            G++  +    +   ++    +   K  +K QA  A +ALAK  Y +LF WI+  VN+AL 
Sbjct: 365  GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424

Query: 446  KTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIE 505
               +Q  SF+G+LDI GFE FE+NSFEQ CINY NEKLQQ FN  +F LEQEEY +E I 
Sbjct: 425  SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483

Query: 506  WNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLC-TEQGSHPKFQ 564
            W  IDF  D QPCI LIE   +  G+L LLDEEC  PK TD ++ +KL  T       F+
Sbjct: 484  WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539

Query: 565  KPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDR 624
            KP+ L +K  F I H+A KV+Y    +L KN D + +    +L +S  K + +L++D ++
Sbjct: 540  KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597

Query: 625  IVGLDQMAKMTESSLP-SASKTKKGM--------FRTVGQLYKEQLGKLMTTLRNTTPNF 675
             +          + L  + +K  KG          +TVG  ++  L  LM TL  TTP++
Sbjct: 598  AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657

Query: 676  VRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANA 735
            VRCI PN  K     D    ++QLR  GVLE IRI   GFP+R  +QEF  RY +L    
Sbjct: 658  VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716

Query: 736  IPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQA 795
                  D KQ C  +++ L LD + Y+ G++KIFFR G +A+LE+ R  K+    +  Q 
Sbjct: 717  -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775

Query: 796  MCRGYLARKAFAK-RQQQLTAMKVI---QRNCAAYLKLRN------WQWWRLFTKVKPLL 845
              RG+L RK + + R+  +T  + +   Q  C A    R        ++WR++       
Sbjct: 776  TIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMY------- 828

Query: 846  QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
             V R+  +++     + ++  R   A N  +++ ++H  +  +K +     +   +    
Sbjct: 829  -VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887

Query: 906  A---EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ-AERKKMAQQMLDLEEQLEE 961
            A    +   R    K+EL+++  ++EAR  E   R ++L      K+ Q    ++EQ ++
Sbjct: 888  AIIYLQCCFRRMMAKRELKKL--KIEARSVE---RYKKLHIGMENKIMQLQRKVDEQNKD 942

Query: 962  EEAARQKLQLEKVTAEAKIKKLEDEI--LVMDDQNNKLSKERKL-LEERISDLTTNLAEE 1018
             +   +KL   +    ++ +KL  ++  L + ++  K++  R L L+E I+ L  +L + 
Sbjct: 943  YKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQT 1002

Query: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEK-SRQELEKLKRKLEGDASDFHEQIADLQAQ 1077
              + K + +  ++++    +L   LK+E    +QE E L  ++   A +  E +      
Sbjct: 1003 RSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETM------ 1056

Query: 1078 IAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA 1137
              E K+    K+ EL      L+DE  +  N L +   LE    DL+E++          
Sbjct: 1057 --EKKLVEETKQLELD-----LNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPG 1109

Query: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQE 1196
             K+      +      E E    S   + E    R +E +  K  LD       + +V E
Sbjct: 1110 HKR-----TDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164

Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAG-ELRVLGQAKQEVEHKKK 1255
            + Q+     +EL  + EQ  R+KA         E+E   + G EL      +QE+E + K
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAK--------EEERPQIRGAELEYESLKRQELESENK 1216

Query: 1256 KLEAQVQELQSKCSD--GERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASL 1313
            KL+ ++ EL+   S+       A        L  ++ SV+  L+  + + + L   + S 
Sbjct: 1217 KLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQ 1276

Query: 1314 SSQLQD-------TQELLQEETRQKLNVSTKLRQL-----EEERNSLQD--QLDEEME-- 1357
               +Q        T   +  E  QK+    ++ Q      E  R+S  D  +L+E+ E  
Sbjct: 1277 KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELW 1336

Query: 1358 -AKQNLERHISTLNIQLSDSKKKLQDFAST----VEALEEGKKRFQKEIENLTQQYEEKA 1412
               + L++    L  QL   K+  ++ A      +++L+E   R Q+++     Q   +A
Sbjct: 1337 LVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNR-QQQLLAQNLQLPPEA 1395

Query: 1413 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1459
                 L+    RL  E  DL+  L+ Q + V  L+K+ + F + + E
Sbjct: 1396 RIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 144/668 (21%), Positives = 271/668 (40%), Gaps = 92/668 (13%)

Query: 1246 AKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIK 1305
            AK+E+  KK K+EA+  E   K   G      + +K+ +LQ +V+               
Sbjct: 901  AKREL--KKLKIEARSVERYKKLHIG------MENKIMQLQRKVDEQN------------ 940

Query: 1306 LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
              KD   L  +L + + +   ET +KL    +  QL EE            EAK    R 
Sbjct: 941  --KDYKCLVEKLTNLEGIYNSET-EKLRSDLERLQLSEE------------EAKVATGRV 985

Query: 1366 ISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY-EEKAAAYDKLEKTKNR 1424
            +S L  +++  +K L+   S  + +EE   R+++E E L     EE      + E   +R
Sbjct: 986  LS-LQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHR 1044

Query: 1425 LQQELDDLVVDLDNQ-----RQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAR 1479
            + Q+  ++   ++ +     +QL  +L  ++ ++  LL E   +  +Y D ++       
Sbjct: 1045 IVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVH 1104

Query: 1480 EKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK-RALE 1538
              +           ++  +  E E       AEMED+ S  ++  +    L+ S    L+
Sbjct: 1105 VPKP-----GHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQ 1159

Query: 1539 TQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQL 1598
             ++ E++ + + ++DEL   E+  LR                    +  EE+R Q++   
Sbjct: 1160 KRVTELEQEKQVMQDELDRKEEQVLR-------------------SKAKEEERPQIRG-- 1198

Query: 1599 HEYETELEDERKQRALAAAAKKKLEGDLKDLE--LQADSAIKGREEAIKQLRKLQAQMKD 1656
                 ELE E  +R    +  KKL+ +L +L   L   SA +         R L  Q+  
Sbjct: 1199 ----AELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTS 1254

Query: 1657 FQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 1716
               EL D R     I  +   ++K+A   + D   + +     E  +K  D  K E+A+ 
Sbjct: 1255 VSEEL-DVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKD--KGEIAQA 1311

Query: 1717 LAS--SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEA-MSDRVRKATQQAEQLSNEL 1773
                   +  +AL   +   +  +  + E L++    +E+ +  + R    +AE L  E+
Sbjct: 1312 YIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEI 1371

Query: 1774 ATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1833
                 + ++  + +QQL  QN +L       E  +++  +  I  L  +   L EQ+E++
Sbjct: 1372 ----QSLKEENNRQQQLLAQNLQLPP-----EARIEASLQHEITRLTNENLDLMEQLEKQ 1422

Query: 1834 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN--ARVKQLKRQLEEAEE 1891
             +  +   K LK   KK+ E+ +   +     +   E     N   + K  +  LE  +E
Sbjct: 1423 DKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKE 1482

Query: 1892 ESQRINAN 1899
            + Q++  N
Sbjct: 1483 DEQKLVKN 1490



 Score = 74.7 bits (182), Expect = 8e-13
 Identities = 122/587 (20%), Positives = 246/587 (41%), Gaps = 61/587 (10%)

Query: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKN----KQTLEKENADLAGELRVLGQAKQEVEH 1252
            M ++  + ++     +E++K+    ++      ++ ++++N D    +  L   +     
Sbjct: 900  MAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNS 959

Query: 1253 KKKKLEAQVQELQSKCSDGERARAE---LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
            + +KL + ++ LQ    + + A      L +++ KL+ ++E         E  A +  ++
Sbjct: 960  ETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQE 1019

Query: 1310 VASLSSQLQDTQELLQEETRQKLN----------VSTKLRQLEEERNSLQDQLDEEMEAK 1359
               L S L++   LL++E ++ LN            T  ++L EE   L+  L++E    
Sbjct: 1020 TEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRY 1078

Query: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQY---EEKAAAYD 1416
            QNL    S L  +  D K+++      V   + G KR      +   +Y    E A   D
Sbjct: 1079 QNLLNEFSRLEERYDDLKEEM---TLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMED 1135

Query: 1417 KLEKTKNRLQQELD-DLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
               +T+   ++++  D+ + L  Q+++    ++KQ   D+L  +E+ +    A E +R +
Sbjct: 1136 IPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQ 1195

Query: 1476 AEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKR 1535
                E E ++L       E  + K EL    K L  +    V++                
Sbjct: 1196 IRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA------------PGAP 1243

Query: 1536 ALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1595
            A    ME++ +  EEL  +++  E   LR ++  Q      +  +Q +D++N      + 
Sbjct: 1244 AYRVLMEQLTSVSEEL--DVRKEEVLILRSQLVSQ------KEAIQPKDDKNTMTDSTI- 1294

Query: 1596 RQLHEYETELEDERKQRALAAAAKKKLEGDLKDL-ELQADSAIKGREEAIKQL-RKLQAQ 1653
              L E   +++D+ +        K+       D  EL  D  +    E +KQ  R L++Q
Sbjct: 1295 --LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ 1352

Query: 1654 MKDFQRELE-DARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE- 1711
            ++  +R  E +A A R EI +  +EN ++ +        L ++L     AR +A L+ E 
Sbjct: 1353 LQSQKRSHENEAEALRGEIQSLKEENNRQQQ-------LLAQNLQLPPEARIEASLQHEI 1405

Query: 1712 -ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE-EQGNMEAMS 1756
              L  E    +          R+L+ ++    +++ E E G ME +S
Sbjct: 1406 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENIS 1452



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 96/464 (20%), Positives = 191/464 (41%), Gaps = 56/464 (12%)

Query: 850  QEEEMQAKEDELQKTKER---QQKAENELKELEQKHSQLTEEKNLLQEQLQA-ETELYAE 905
            QEE  + ++D  Q   E+   ++ A+   +E EQ  S L EE  LL+++ +A    +  +
Sbjct: 989  QEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQ 1048

Query: 906  AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQL------ 959
            A+EM   +  K   L E   ++E  L +E  R Q L  E  ++ ++  DL+E++      
Sbjct: 1049 AKEMTETMEKK---LVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105

Query: 960  -----EEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
                 +  ++     + E + + ++I ++ED     ++ + K       L  ++    T 
Sbjct: 1106 PKPGHKRTDSTHSSNESEYIFS-SEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164

Query: 1015 LAEEEE--------KAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD 1066
            L +E++        K + + + K K E         L+ E   RQELE   +KL+ + ++
Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNE 1224

Query: 1067 FHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEI-AQKNNALKKIRELEGHISDLQE 1125
              + +++  A   E+    A     L   L  + +E+  +K   L    +L      +Q 
Sbjct: 1225 LRKALSEKSAP--EVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282

Query: 1126 DLDSERAARN----KAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKK 1181
              D      +    +  ++ +D GE  +A     E    S     EL    + E+ ++ +
Sbjct: 1283 KDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELN--EDGELWLVYE 1340

Query: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK--------------------RAKAN 1221
             L +  R  E+Q+Q  ++ H    E L  +++  K                    R +A+
Sbjct: 1341 GLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1400

Query: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
            L      L  EN DL  +L    +  ++++ + K    ++ EL+
Sbjct: 1401 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444



 Score = 65.1 bits (157), Expect = 6e-10
 Identities = 92/354 (25%), Positives = 157/354 (44%), Gaps = 52/354 (14%)

Query: 1611 QRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQL-RKLQAQMKDFQ------RELED 1663
            +R +A    KKL+ + + +E      I G E  I QL RK+  Q KD++        LE 
Sbjct: 897  RRMMAKRELKKLKIEARSVERYKKLHI-GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG 955

Query: 1664 ARASRDEIFATAKE----NEKKAKSLEADLMQLQEDLAAAERARKQADLEK--------- 1710
               S  E   +  E    +E++AK     ++ LQE++A   +  +Q   EK         
Sbjct: 956  IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADR 1015

Query: 1711 -EELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQ 1768
             ++  E+L S+L   N  L+ EK  L  RI Q  +E+ E    ME      +K  ++ +Q
Sbjct: 1016 YKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTE---TME------KKLVEETKQ 1066

Query: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA---------L 1819
            L  +L  ER   Q   +   +LE +  +L+ ++  M    K   K T +           
Sbjct: 1067 LELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIF 1126

Query: 1820 EAKIAQLEE---QVEQEAREKQAATKSLKQK-DKKLKEI-----LLQVEDERKMAEQYKE 1870
             ++IA++E+   + E+ + +K     SL  K  K++ E+     ++Q E +RK  EQ   
Sbjct: 1127 SSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRK-EEQVLR 1185

Query: 1871 QAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATES-NEAMGREVNA 1923
               K   R +    +LE    + Q + +  +KL+ EL+E  ++ +E    EV A
Sbjct: 1186 SKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTA 1239



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 96/516 (18%), Positives = 200/516 (38%), Gaps = 79/516 (15%)

Query: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHE 1529
            E  + + EAR  E           + ++ + +++  NK  K  +E L + +        +
Sbjct: 904  ELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEK 963

Query: 1530 LEKSKRALETQMEEMKT----------QLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
            L      L+   EE K           ++ +L  +L+ T   K  +E +    K + E+ 
Sbjct: 964  LRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQL 1023

Query: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
            +    E+N   +++ +   H    + ++      +    +KKL  + K LEL  +     
Sbjct: 1024 VSNLKEENTLLKQEKEALNHRIVQQAKE------MTETMEKKLVEETKQLELDLNDERLR 1077

Query: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1699
             +  + +  +L+ +  D + E+         +    K   K+  S  +      E + ++
Sbjct: 1078 YQNLLNEFSRLEERYDDLKEEMT-------LMVHVPKPGHKRTDSTHSS--NESEYIFSS 1128

Query: 1700 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1759
            E A  +    + E   E    L     L     +L+ R+ +LE+E +  Q  ++   ++V
Sbjct: 1129 EIAEMEDIPSRTEEPSEKKVPLDMSLFL-----KLQKRVTELEQEKQVMQDELDRKEEQV 1183

Query: 1760 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA- 1818
             ++  + E+       E    +     RQ+LE +NK+L+++L+E+  A+  K    + A 
Sbjct: 1184 LRSKAKEEERPQIRGAE---LEYESLKRQELESENKKLKNELNELRKALSEKSAPEVTAP 1240

Query: 1819 -------LEAKIAQLEEQVEQEARE-------KQAATKSLKQKDKK--LKEILLQVEDER 1862
                   L  ++  + E+++    E         +  ++++ KD K  + +  + +ED +
Sbjct: 1241 GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ 1300

Query: 1863 KMAEQ--------------------YKEQAEKGN-----ARVKQLKRQLEEAEEESQRIN 1897
            KM ++                    Y E  E G        +KQ  R LE   +  +R +
Sbjct: 1301 KMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQLQSQKRSH 1360

Query: 1898 ANRRK-LQRELDEATESNEAMGREVNALKSKLRGPP 1932
             N  + L+ E+    E N    R+   L   L+ PP
Sbjct: 1361 ENEAEALRGEIQSLKEEN---NRQQQLLAQNLQLPP 1393



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 34/173 (19%)

Query: 846  QVTRQEEEMQAKED------------ELQKTKERQQKAE-------------------NE 874
            Q+  Q+E +Q K+D            ++QK K++ + A+                   NE
Sbjct: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNE 1331

Query: 875  LKELEQKHSQLTEEKNLLQEQLQAETELYA-EAEEMRVRLAAKKQE--LEEILHEMEARL 931
              EL   +  L +   LL+ QLQ++   +  EAE +R  + + K+E   ++ L     +L
Sbjct: 1332 DGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQL 1391

Query: 932  EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
              E      LQ E  ++  + LDL EQLE+++   +KL+ +      KI +LE
Sbjct: 1392 PPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  513 bits (1320), Expect = e-145
 Identities = 342/1013 (33%), Positives = 559/1013 (55%), Gaps = 61/1013 (6%)

Query: 36   VWVPSEKQGFEAASIKEEKGDEVVVELVENG-----KKVTVGKDDIQKMNPPKFSKVEDM 90
            VW+    Q F +      +G  +VV   + G     K+ T+    +  M+P     V+DM
Sbjct: 11   VWLRENGQHFPSTVNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDM 68

Query: 91   AELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHE 149
            A LT L+  S+++NL +RY    IYTY G     VNPY+ +  +Y    ++ Y  +   E
Sbjct: 69   ASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGE 128

Query: 150  MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
            +PPHI+AIA+  YR + +  ++Q IL +GESGAGKTE+TK ++++L+V++          
Sbjct: 129  LPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKE 188

Query: 210  ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
             T  +E+ +L+++PI+EAFGNAKTV N+NSSRFGKF+++N    G I G  I  YLLEK+
Sbjct: 189  KTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKN 248

Query: 270  RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMFQE 328
            R +RQ   ER +HIFY ++AG + + R +  L    NY +L+ +G V      D E F+E
Sbjct: 249  RVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISDQESFRE 308

Query: 329  TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388
             + AM +M FS+EE   + ++++ +L LGNI F        A +   TA  +   L+G++
Sbjct: 309  VITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELLGLD 365

Query: 389  VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448
             T  T ++    + +  + +      +QA  + ++LA A Y   F W++ ++N  +    
Sbjct: 366  PTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRI--KG 423

Query: 449  RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508
             +    +GILDI GFE FEVN FEQ  INY NEKLQ+ FN  +F LEQ EY REG+ W  
Sbjct: 424  NEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWED 483

Query: 509  IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ 568
            ID+ +D   C++LIE+     G+LAL++EE  FP+ATD + +EKL ++  ++  + KP+ 
Sbjct: 484  IDW-IDNGECLDLIEK---KLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRV 539

Query: 569  LKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
              +   F + HYAG+V Y+    L KN D   D++ +LL  S   F+ DL++ V      
Sbjct: 540  AVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVS----- 592

Query: 629  DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
               ++  + +L   SK ++    TV   +K+ L  LM TL ++ P FVRCI PN +K   
Sbjct: 593  ---SRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646

Query: 689  KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN-AIPKGFMDGKQAC 747
            + D  +VL QLR +G+LE +RI + G+  R  FQ+F +RY++L  N A+P+   D +  C
Sbjct: 647  QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE---DVRGKC 703

Query: 748  ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
              +++  +   + +++G++K+F R  +   LE+ R+ +++   M  +A   G+LARK + 
Sbjct: 704  TSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYR 763

Query: 808  KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
            K    L  + +IQ+N  A+L  R     R     K  +   +Q     A+    Q   E+
Sbjct: 764  K---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK 815

Query: 868  QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
            +++ E + +E E+K  +  EE+   +E+ + E EL A+ EE       K+QELE +    
Sbjct: 816  REQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEE----TRKQQELEAL---Q 866

Query: 928  EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
            +++ E E  R  + Q E K++ +++L LE+++E+ +  R K Q E    EA ++KL++  
Sbjct: 867  KSQKEAELTRELEKQKENKQV-EEILRLEKEIEDLQ--RMKEQQELSLTEASLQKLQER- 922

Query: 988  LVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1039
               D +  +L +E  +  +E +  L  N  E +E  +N+ +  +      SEL
Sbjct: 923  --RDQELRRLEEEACRAAQEFLESL--NFDEIDECVRNIERSLSVGSEFSSEL 971



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 49/195 (25%), Positives = 88/195 (45%), Gaps = 21/195 (10%)

Query: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
            R++ RQL   + E E+++KQ       KKK E + ++ E         RE    +LR  Q
Sbjct: 805  RRVYRQLLAEKREQEEKKKQEE---EEKKKREEEERERE---------RERREAELRAQQ 852

Query: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
             +    Q+ELE  + S+ E   T +  ++K      ++++L++++   +R ++Q +L   
Sbjct: 853  EEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL--- 909

Query: 1712 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR---KATQQAEQ 1768
             L E     L  R     E RRLE    +  +E  E   N + + + VR   ++     +
Sbjct: 910  SLTEASLQKLQERR--DQELRRLEEEACRAAQEFLESL-NFDEIDECVRNIERSLSVGSE 966

Query: 1769 LSNELATERSTAQKN 1783
             S+ELA      + N
Sbjct: 967  FSSELAESACEEKPN 981



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 52/237 (21%), Positives = 101/237 (42%), Gaps = 19/237 (8%)

Query: 874  ELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR--- 930
            +L +      QL + K  L+E L+ + E   E E     +  +   L  +  +   +   
Sbjct: 708  QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767

Query: 931  ---LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL--EKVTAEAKIKKLED 985
               + ++  R   L+     + +  +  ++QL  + A R   QL  EK   E K K+ E+
Sbjct: 768  CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE 827

Query: 986  EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
            E    +++  +  +ER     R ++L     EE  K + L  L+   +      E+  +K
Sbjct: 828  EKKKREEEERERERER-----REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882

Query: 1046 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
            E K  +E+ +L++++E D     E     Q +++  +  L K +E     L RL++E
Sbjct: 883  ENKQVEEILRLEKEIE-DLQRMKE-----QQELSLTEASLQKLQERRDQELRRLEEE 933



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 45/231 (19%)

Query: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
            QL  +    E  +KQ + EK++  EE           + E+ R EA +   +EE   +Q 
Sbjct: 810  QLLAEKREQEEKKKQEEEEKKKREEE---------ERERERERREAELRAQQEEETRKQQ 860

Query: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
             +EA+     + +Q+  +L+ EL  ++   Q  E  R  LE++ ++L+    + E     
Sbjct: 861  ELEAL-----QKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQE----- 908

Query: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQKD-KKLKEILLQVEDERKM 1864
                 ++  EA + +L+E+ +QE R  +     AA + L+  +  ++ E +  +E    +
Sbjct: 909  -----LSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSV 963

Query: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
              ++  +               E A EE    N ++   + E+DE  E+++
Sbjct: 964  GSEFSSEL-------------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 42/193 (21%), Positives = 87/193 (45%), Gaps = 10/193 (5%)

Query: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
            L+K     Q++L   +     ++ L    E++++K  +   ++K    +   ER+R EAE
Sbjct: 788  LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847

Query: 1478 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
             R ++ +     + LE   ++++E E T ++ K +    V     + K + +L++ K   
Sbjct: 848  LRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQ 907

Query: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
            E  + E   Q      +LQ   D +LR  +  +A +   E       ++ +E  R ++R 
Sbjct: 908  ELSLTEASLQ------KLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIERS 960

Query: 1598 L---HEYETELED 1607
            L    E+ +EL +
Sbjct: 961  LSVGSEFSSELAE 973



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 24/156 (15%)

Query: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKR 1058
            R+LL E+         EEEEK K   + + + E    E E+R ++EE++R  QELE L++
Sbjct: 809  RQLLAEKREQEEKKKQEEEEKKKREEE-ERERERERREAELRAQQEEETRKQQELEALQK 867

Query: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA-ALARLDDEI--AQKNNALKKIRE 1115
                              + AEL  +L K++E  Q   + RL+ EI   Q+    +++  
Sbjct: 868  ----------------SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSL 911

Query: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151
             E  +  LQE  D E   R   E+  R   E LE+L
Sbjct: 912  TEASLQKLQERRDQE--LRRLEEEACRAAQEFLESL 945



 Score = 40.0 bits (92), Expect = 0.022
 Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 15/154 (9%)

Query: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
            E  E+ +K+ Q+E E   ++ EE+       E+ + R + EL     +   ++Q +  L+
Sbjct: 814  EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866

Query: 1448 KKQRKFDQLLAEEKNISSKYADERDRAEAE----AREKETKALSLARALEEALEAK--EE 1501
            K Q++ +     EK   +K  +E  R E E     R KE + LSL  A  + L+ +  +E
Sbjct: 867  KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926

Query: 1502 LER-TNKMLKAEMEDLVS-SKDDVGKNVHELEKS 1533
            L R   +  +A  E L S + D++ + V  +E+S
Sbjct: 927  LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960



 Score = 39.7 bits (91), Expect = 0.029
 Identities = 88/372 (23%), Positives = 149/372 (40%), Gaps = 54/372 (14%)

Query: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
            +R   L  NLA  E+     T L   +++  SE ++   K        +KL+++ E + S
Sbjct: 684  KRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVS 743

Query: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD--- 1122
                  A +  +   L     K+  ++   +      I QKN     +R    H+     
Sbjct: 744  H-----AAMVIRAHVLGFLARKQYRKVLYCVV-----IIQKNYRAFLLRRRFLHLKKAAI 793

Query: 1123 -LQEDLDSERAAR-------NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
              Q+ L  + A R        K E++++   EE E  K E          ++E   +RE+
Sbjct: 794  VFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKRE----------EEERERERER 843

Query: 1175 EVTVLKKALDEETR-SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1233
                L+   +EETR   E +  +  QK A    ELT +LE+ K       +NKQ   +E 
Sbjct: 844  REAELRAQQEEETRKQQELEALQKSQKEA----ELTRELEKQK-------ENKQV--EEI 890

Query: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
              L  E+  L + K++ E      EA +Q+LQ +  D E  R E  +     Q  +ES+ 
Sbjct: 891  LRLEKEIEDLQRMKEQQE--LSLTEASLQKLQER-RDQELRRLE-EEACRAAQEFLESLN 946

Query: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
               +E +     + +   SLS   + + EL +    +K N +      EEE +   +  D
Sbjct: 947  --FDEIDECVRNIER---SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADD 1001

Query: 1354 EEMEAKQNLERH 1365
            +  +   N   H
Sbjct: 1002 DAFKDSPNPSEH 1013



 Score = 38.5 bits (88), Expect = 0.064
 Identities = 56/219 (25%), Positives = 100/219 (45%), Gaps = 34/219 (15%)

Query: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
            ++LL E+  Q+     K +Q EEE+        EE E ++  ER  + L  Q  +  +K 
Sbjct: 809  RQLLAEKREQE----EKKKQEEEEKKKR-----EEEERERERERREAELRAQQEEETRKQ 859

Query: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
            Q+    +EAL++     QKE E LT++ E++    +K  +   RL++E++DL   +  Q+
Sbjct: 860  QE----LEALQKS----QKEAE-LTRELEKQKE--NKQVEEILRLEKEIEDL-QRMKEQQ 907

Query: 1441 QL---VSNLEKKQRKFDQLL---------AEEKNISSKYADERDRAEAEAREKETKALSL 1488
            +L    ++L+K Q + DQ L         A ++ + S   DE D          +     
Sbjct: 908  ELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967

Query: 1489 ARAL-EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
            +  L E A E K     +    + E+++   + DD  K+
Sbjct: 968  SSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKD 1006



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 8/115 (6%)

Query: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER-HISTLNIQLSDS 1376
            Q+ ++  +EE ++K     + R+ E     L+ Q +EE   +Q LE    S    +L+  
Sbjct: 818  QEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRE 877

Query: 1377 KKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDK--LEKTKNRLQQEL 1429
             +K ++     E L     R +KEIE+L +  E++  +  +  L+K + R  QEL
Sbjct: 878  LEKQKENKQVEEIL-----RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  497 bits (1280), Expect = e-140
 Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)

Query: 59  VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
           VV+L ++G+   V  +D            I+ M+P     VEDM  L  LNEA +L NL 
Sbjct: 27  VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86

Query: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
            RY   LIYTY+G   V VNPY+ L IYS + +  Y  KK  EMPPHI+AIAD  Y +M 
Sbjct: 87  IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146

Query: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
           ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H           +E+Q+L+A PILE
Sbjct: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197

Query: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
           AFGNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA DER +H+FY 
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
           M+ G  E  +  L L   ++Y +L+ G  +      D + +     AM ++ F++ E   
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
           I K+++++L LGN+ ++     N D   +  + +      L+ +N  D   S LT R  +
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376

Query: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
            R + V    ++EQA    +A  K  Y RLF WI+ ++N A+ K   Q        +G+L
Sbjct: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436

Query: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
           DI GFE F VNSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495

Query: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
           +++I   N P  +++L+DEE  FPK TD + + KL ++   +  +  PK    +T+F I 
Sbjct: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552

Query: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
           H+AG V Y    +L KN D L+ ++  L+++S +KF+  ++                ++ 
Sbjct: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596

Query: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
           +   ++T+K    T+   +K  L  LM TL    P FVRCI PN  K+    D  L + Q
Sbjct: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655

Query: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
           LR +G++E IRI R G+P R  F EF +RY +L     P     D +  C  M +A+   
Sbjct: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715

Query: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
            + ++IG++KIF +      LE ERD  ITD ++  Q + RG+  R  F K +   T   
Sbjct: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772

Query: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
           +IQR+   +   +N+   RL F +++ L +  +  ++ +      Q+  + Q +    L 
Sbjct: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829

Query: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
               +H   + LT +          L ++L+AE     EAE+MR+       E E++  E
Sbjct: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883

Query: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
           M A+  +EE       AERK   ++AQ    D E +L+E+EAAR+K +L
Sbjct: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
           I+ FQA CR YL RKAF  R   +  ++   R   A   + +LR    WRL  +   L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876

Query: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
             +  +EM   +AKE+  +K +ER  +   E  E E K  +    K  L EQ++
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930



 Score = 35.4 bits (80), Expect = 0.55
 Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)

Query: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
            ++RL +EEK R+E+   K K E +     E++A L  + AE ++   + A++++EL   +
Sbjct: 871  KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929

Query: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
             R   E    ++ + K+    G    L        +     E+ +R++ EE L+A   L 
Sbjct: 930  ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989

Query: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
             E E+ L S     +  A   Q  T     ++ L +    H+ +  ++            
Sbjct: 990  DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048

Query: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
                   K+  A+ + +E++    +    L K     E +     GE ++  GQ K  V 
Sbjct: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108

Query: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
            HK      KK     +E+  +  DGE
Sbjct: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  497 bits (1280), Expect = e-140
 Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)

Query: 59  VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
           VV+L ++G+   V  +D            I+ M+P     VEDM  L  LNEA +L NL 
Sbjct: 27  VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86

Query: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
            RY   LIYTY+G   V VNPY+ L IYS + +  Y  KK  EMPPHI+AIAD  Y +M 
Sbjct: 87  IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146

Query: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
           ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H           +E+Q+L+A PILE
Sbjct: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197

Query: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
           AFGNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA DER +H+FY 
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
           M+ G  E  +  L L   ++Y +L+ G  +      D + +     AM ++ F++ E   
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
           I K+++++L LGN+ ++     N D   +  + +      L+ +N  D   S LT R  +
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376

Query: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
            R + V    ++EQA    +A  K  Y RLF WI+ ++N A+ K   Q        +G+L
Sbjct: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436

Query: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
           DI GFE F VNSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495

Query: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
           +++I   N P  +++L+DEE  FPK TD + + KL ++   +  +  PK    +T+F I 
Sbjct: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552

Query: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
           H+AG V Y    +L KN D L+ ++  L+++S +KF+  ++                ++ 
Sbjct: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596

Query: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
           +   ++T+K    T+   +K  L  LM TL    P FVRCI PN  K+    D  L + Q
Sbjct: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655

Query: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
           LR +G++E IRI R G+P R  F EF +RY +L     P     D +  C  M +A+   
Sbjct: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715

Query: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
            + ++IG++KIF +      LE ERD  ITD ++  Q + RG+  R  F K +   T   
Sbjct: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772

Query: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
           +IQR+   +   +N+   RL F +++ L +  +  ++ +      Q+  + Q +    L 
Sbjct: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829

Query: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
               +H   + LT +          L ++L+AE     EAE+MR+       E E++  E
Sbjct: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883

Query: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
           M A+  +EE       AERK   ++AQ    D E +L+E+EAAR+K +L
Sbjct: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
           I+ FQA CR YL RKAF  R   +  ++   R   A   + +LR    WRL  +   L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876

Query: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
             +  +EM   +AKE+  +K +ER  +   E  E E K  +    K  L EQ++
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930



 Score = 35.4 bits (80), Expect = 0.55
 Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)

Query: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
            ++RL +EEK R+E+   K K E +     E++A L  + AE ++   + A++++EL   +
Sbjct: 871  KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929

Query: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
             R   E    ++ + K+    G    L        +     E+ +R++ EE L+A   L 
Sbjct: 930  ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989

Query: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
             E E+ L S     +  A   Q  T     ++ L +    H+ +  ++            
Sbjct: 990  DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048

Query: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
                   K+  A+ + +E++    +    L K     E +     GE ++  GQ K  V 
Sbjct: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108

Query: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
            HK      KK     +E+  +  DGE
Sbjct: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  497 bits (1280), Expect = e-140
 Identities = 344/949 (36%), Positives = 512/949 (53%), Gaps = 86/949 (9%)

Query: 59  VVELVENGKKVTVGKDD------------IQKMNPPKFSKVEDMAELTCLNEASVLHNLR 106
           VV+L ++G+   V  +D            I+ M+P     VEDM  L  LNEA +L NL 
Sbjct: 27  VVKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLL 86

Query: 107 ERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKKRHEMPPHIYAIADTAYRSML 166
            RY   LIYTY+G   V VNPY+ L IYS + +  Y  KK  EMPPHI+AIAD  Y +M 
Sbjct: 87  IRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMK 146

Query: 167 QDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTSITGELEKQLLQANPILE 226
           ++  DQ  + +GESGAGKTE+TK ++Q+LA ++  H           +E+Q+L+A PILE
Sbjct: 147 RNSRDQCCIISGESGAGKTESTKLILQFLAAISGQHSW---------IEQQVLEATPILE 197

Query: 227 AFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYY 286
           AFGNAKT++NDNSSRFGK+I I+F+  G I GA IE YLLEKSR  RQA DER +H+FY 
Sbjct: 198 AFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYC 257

Query: 287 MIAGAKEKMRSDLLLEGFNNYTFLSNG-FVPIPAAQDDEMFQETVEAMAIMGFSEEEQLS 345
           M+ G  E  +  L L   ++Y +L+ G  +      D + +     AM ++ F++ E   
Sbjct: 258 MLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWE 317

Query: 346 ILKVVSSVLQLGNIVFKKE--RNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKV 403
           I K+++++L LGN+ ++     N D   +  + +      L+ +N  D   S LT R  +
Sbjct: 318 ISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDL-MSCLTSRTLI 376

Query: 404 GR-DVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGAS----FLGIL 458
            R + V    ++EQA    +A  K  Y RLF WI+ ++N A+ K   Q        +G+L
Sbjct: 377 TRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLL 436

Query: 459 DIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPC 518
           DI GFE F VNSFEQLCIN+ NE LQQ F   +F LEQEEY  E I+W  I+F  D Q  
Sbjct: 437 DIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDA 495

Query: 519 IELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSII 578
           +++I   N P  +++L+DEE  FPK TD + + KL ++   +  +  PK    +T+F I 
Sbjct: 496 LDMI--ANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGIN 552

Query: 579 HYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTESS 638
           H+AG V Y    +L KN D L+ ++  L+++S +KF+  ++                ++ 
Sbjct: 553 HFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIF----------------QAD 596

Query: 639 LPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQ 698
           +   ++T+K    T+   +K  L  LM TL    P FVRCI PN  K+    D  L + Q
Sbjct: 597 VAMGAETRK-RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQ 655

Query: 699 LRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFM-DGKQACILMIKALELD 757
           LR +G++E IRI R G+P R  F EF +RY +L     P     D +  C  M +A+   
Sbjct: 656 LRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGT 715

Query: 758 PNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMK 817
            + ++IG++KIF +      LE ERD  ITD ++  Q + RG+  R  F K +   T   
Sbjct: 716 HDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAAT--- 772

Query: 818 VIQRNCAAYLKLRNWQWWRL-FTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELK 876
           +IQR+   +   +N+   RL F +++ L +  +  ++ +      Q+  + Q +    L 
Sbjct: 773 LIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLAR---QRIIQFQARCRAYLV 829

Query: 877 ELEQKH---SQLTEE-------KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
               +H   + LT +          L ++L+AE     EAE+MR+       E E++  E
Sbjct: 830 RKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRL------AEEEKLRKE 883

Query: 927 MEARLEEEEDRGQQLQAERK---KMAQ-QMLDLEEQLEEEEAARQKLQL 971
           M A+  +EE       AERK   ++AQ    D E +L+E+EAAR+K +L
Sbjct: 884 MSAKKAKEE-------AERKHQERLAQLAREDAERELKEKEAARRKKEL 925



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 6/114 (5%)

Query: 790 IMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA---YLKLRNWQWWRLFTKVKPLLQ 846
           I+ FQA CR YL RKAF  R   +  ++   R   A   + +LR    WRL  +   L +
Sbjct: 817 IIQFQARCRAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAE 876

Query: 847 VTRQEEEM---QAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQ 897
             +  +EM   +AKE+  +K +ER  +   E  E E K  +    K  L EQ++
Sbjct: 877 EEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQME 930



 Score = 35.4 bits (80), Expect = 0.55
 Identities = 59/266 (22%), Positives = 108/266 (40%), Gaps = 35/266 (13%)

Query: 1040 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM---QLAKKEEELQAAL 1096
            ++RL +EEK R+E+   K K E +     E++A L  + AE ++   + A++++EL   +
Sbjct: 871  KMRLAEEEKLRKEMSAKKAKEEAERK-HQERLAQLAREDAERELKEKEAARRKKELLEQM 929

Query: 1097 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE-LEA---LK 1152
             R   E    ++ + K+    G    L        +     E+ +R++ EE L+A   L 
Sbjct: 930  ERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLP 989

Query: 1153 TELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM------------ 1197
             E E+ L S     +  A   Q  T     ++ L +    H+ +  ++            
Sbjct: 990  DEDEEDL-SEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRF 1048

Query: 1198 -----RQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRV-LGQAKQEVE 1251
                   K+  A+ + +E++    +    L K     E +     GE ++  GQ K  V 
Sbjct: 1049 MGDLPEPKYHTAMSDGSEKIPVMTKIYETLGKKTYKRELQALQGEGEAQLPEGQKKSSVR 1108

Query: 1252 HK-----KKKLEAQVQELQSKCSDGE 1272
            HK      KK     +E+  +  DGE
Sbjct: 1109 HKLVHLTLKKKSKLTEEVTKRLHDGE 1134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,132,900
Number of Sequences: 37866
Number of extensions: 3045380
Number of successful extensions: 99931
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1146
Number of HSP's successfully gapped in prelim test: 1694
Number of HSP's that attempted gapping in prelim test: 16251
Number of HSP's gapped (non-prelim): 25239
length of query: 1938
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1821
effective length of database: 13,817,196
effective search space: 25161113916
effective search space used: 25161113916
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.