Guide to the Human Genome
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Search of human proteins with 4504711

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504711 insulin-like 4 precursor [Homo sapiens]
         (139 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504711 insulin-like 4 precursor [Homo sapiens]                    289   6e-79
gi|5902052 relaxin 1 preproprotein [Homo sapiens]                      45   2e-05
gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens]           44   4e-05
gi|21361116 versican isoform 1 [Homo sapiens]                          30   0.48 
gi|169167792 PREDICTED: similar to hCG1745223 [Homo sapiens]           29   1.1  
gi|88987622 PREDICTED: similar to hCG1745223 [Homo sapiens]            29   1.1  
gi|4758420 glial cells missing homolog 2 [Homo sapiens]                29   1.1  
gi|219803946 within bgcn homolog isoform 2 [Homo sapiens]              29   1.4  
gi|14150139 within bgcn homolog isoform 1 [Homo sapiens]               29   1.4  
gi|51464815 PREDICTED: similar to hCG1745223 [Homo sapiens]            28   1.8  
gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]      28   1.8  
gi|62988344 P antigen family, member 3 (prostate associated) [Ho...    28   3.1  
gi|115647981 glutamine and serine rich 1 [Homo sapiens]                28   3.1  
gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]                  27   4.1  
gi|209862789 microtubule associated monoxygenase, calponin and L...    27   4.1  
gi|58330892 interferon-induced protein with tetratricopeptide re...    27   5.4  
gi|116534937 interferon-induced protein with tetratricopeptide r...    27   7.0  
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]              27   7.0  
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ...    26   9.1  
gi|93102424 hypothetical protein LOC23116 [Homo sapiens]               26   9.1  

>gi|4504711 insulin-like 4 precursor [Homo sapiens]
          Length = 139

 Score =  289 bits (739), Expect = 6e-79
 Identities = 139/139 (100%), Positives = 139/139 (100%)

Query: 1   MASLFRSYLPAIWLLLSQLLRESLAAELRGCGPRFGKHLLSYCPMPEKTFTTTPGGWLLE 60
           MASLFRSYLPAIWLLLSQLLRESLAAELRGCGPRFGKHLLSYCPMPEKTFTTTPGGWLLE
Sbjct: 1   MASLFRSYLPAIWLLLSQLLRESLAAELRGCGPRFGKHLLSYCPMPEKTFTTTPGGWLLE 60

Query: 61  SGRPKEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKKIILSRKKRSGRHRF 120
           SGRPKEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKKIILSRKKRSGRHRF
Sbjct: 61  SGRPKEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKKIILSRKKRSGRHRF 120

Query: 121 DPFCCEVICDDGTSVKLCT 139
           DPFCCEVICDDGTSVKLCT
Sbjct: 121 DPFCCEVICDDGTSVKLCT 139


>gi|5902052 relaxin 1 preproprotein [Homo sapiens]
          Length = 185

 Score = 45.1 bits (105), Expect = 2e-05
 Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 1   MASLFRSYLPAIWLLLSQLLRESLAAE-----LRGCGPRFGKHLLSYCPMPEKTFTTTPG 55
           M  LF  +L    LLL+Q  R ++AA+     ++ CG    +  ++ C M   +  +   
Sbjct: 1   MPRLFLFHLLEFCLLLNQFSR-AVAAKWKDDVIKLCGRELVRAQIAICGMSTWSKRSLSQ 59

Query: 56  GWLLESGRP-KEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKKI 107
               ++ RP  E+V +  NKD + +    EFI NL PELK  LSE QPSL ++
Sbjct: 60  EDAPQTPRPVAEIVPSFINKDTETIIIMLEFIANLPPELKAALSERQPSLPEL 112


>gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens]
          Length = 185

 Score = 43.9 bits (102), Expect = 4e-05
 Identities = 36/112 (32%), Positives = 57/112 (50%), Gaps = 5/112 (4%)

Query: 1   MASLFRSYLPAIWLLLSQLLR---ESLAAE-LRGCGPRFGKHLLSYCPMPEKTFTTTPGG 56
           M  LF  +L  + LLL+Q  R   +S   E ++ CG    +  ++ C M   +  +    
Sbjct: 1   MPRLFFFHLLGVCLLLNQFSRAVADSWMEEVIKLCGRELVRAQIAICGMSTWSKRSLSQE 60

Query: 57  WLLESGRP-KEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKKI 107
              ++ RP  E+V +  NKD + +   SEF+ NL  ELK  LSE QP+L ++
Sbjct: 61  DAPQTPRPVAEIVPSFINKDTETINMMSEFVANLPQELKLTLSEMQPALPQL 112


>gi|21361116 versican isoform 1 [Homo sapiens]
          Length = 3396

 Score = 30.4 bits (67), Expect = 0.48
 Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 44   PMPEKTFTTTPG--GWLLESGRPKEMVSTSNNKDGQALGTTSEFIPNL 89
            P+P K+ T  P   G   E+    +M  +S   DGQA+   SE IP L
Sbjct: 2694 PIPRKSATVIPEIEGIKAEAKALDDMFESSTLSDGQAIADQSEIIPTL 2741


>gi|169167792 PREDICTED: similar to hCG1745223 [Homo sapiens]
          Length = 320

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 21/105 (20%)

Query: 38  HLLSYCPMPEKTFTTTPGGWLLESGRPKEM-VSTSNNKDG----------------QALG 80
           HL S+C +P KT T+   GW  +  + K++ +  S  +DG                   G
Sbjct: 36  HLKSFCQVPIKTATS---GWGAKKKKAKQLGILLSRKEDGIPPRSCVSCGEEKPLVPRRG 92

Query: 81  TTSEFIP-NLSPELKKPLSEGQPSLKKIILSRKKRSGRHRFDPFC 124
            +S  IP N+S   + P  +G   LK + +S  + +      P C
Sbjct: 93  ASSPQIPLNISGSSEPPPQKGDAKLKGVRMSTLQTAETKPRTPTC 137


>gi|88987622 PREDICTED: similar to hCG1745223 [Homo sapiens]
          Length = 320

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 27/105 (25%), Positives = 44/105 (41%), Gaps = 21/105 (20%)

Query: 38  HLLSYCPMPEKTFTTTPGGWLLESGRPKEM-VSTSNNKDG----------------QALG 80
           HL S+C +P KT T+   GW  +  + K++ +  S  +DG                   G
Sbjct: 36  HLKSFCQVPIKTATS---GWGAKKKKAKQLGILLSRKEDGIPPRSCVSCGEEKPLVPRRG 92

Query: 81  TTSEFIP-NLSPELKKPLSEGQPSLKKIILSRKKRSGRHRFDPFC 124
            +S  IP N+S   + P  +G   LK + +S  + +      P C
Sbjct: 93  ASSPQIPLNISGSSEPPPQKGDAKLKGVRMSTLQTAETKPRTPTC 137


>gi|4758420 glial cells missing homolog 2 [Homo sapiens]
          Length = 506

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 1/66 (1%)

Query: 50  FTTTPGGWLLESGRPKEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKKIIL 109
           FT    GW    G+P  +V  +N+   QA+ T   + P L          G P+L+ +I 
Sbjct: 326 FTNKQHGWKPALGKPS-LVERTNHGQFQAMATRPYYNPELPCRYLTTPPPGAPALQTVIT 384

Query: 110 SRKKRS 115
           +  K S
Sbjct: 385 TTTKVS 390


>gi|219803946 within bgcn homolog isoform 2 [Homo sapiens]
          Length = 203

 Score = 28.9 bits (63), Expect = 1.4
 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 5/61 (8%)

Query: 64  PKEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSE-----GQPSLKKIILSRKKRSGRH 118
           P+E V    NK  +   +  E  P LSPE   P++      G+P L K      KR  + 
Sbjct: 37  PQEEVPVYENKYVKFFKSKPELPPGLSPEATAPVTPSRPEGGEPGLSKTAKRNLKRKEKR 96

Query: 119 R 119
           R
Sbjct: 97  R 97


>gi|14150139 within bgcn homolog isoform 1 [Homo sapiens]
          Length = 204

 Score = 28.9 bits (63), Expect = 1.4
 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 5/61 (8%)

Query: 64  PKEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSE-----GQPSLKKIILSRKKRSGRH 118
           P+E V    NK  +   +  E  P LSPE   P++      G+P L K      KR  + 
Sbjct: 38  PQEEVPVYENKYVKFFKSKPELPPGLSPEATAPVTPSRPEGGEPGLSKTAKRNLKRKEKR 97

Query: 119 R 119
           R
Sbjct: 98  R 98


>gi|51464815 PREDICTED: similar to hCG1745223 [Homo sapiens]
          Length = 319

 Score = 28.5 bits (62), Expect = 1.8
 Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 21/91 (23%)

Query: 38  HLLSYCPMPEKTFTTTPGGWLLESGRPKEM-VSTSNNKDG----------------QALG 80
           HL S+C +P KT T+   GW  +  + K++ +  S  +DG                   G
Sbjct: 36  HLKSFCQVPIKTATS---GWGAKKKKAKQLGILLSRKEDGIPPRSCVSCGEEKPLVPRRG 92

Query: 81  TTSEFIP-NLSPELKKPLSEGQPSLKKIILS 110
            +S  IP N+S   + P  +G   LK + +S
Sbjct: 93  ASSPQIPLNISGSSEPPPQKGDAKLKGVRMS 123


>gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]
          Length = 1278

 Score = 28.5 bits (62), Expect = 1.8
 Identities = 12/24 (50%), Positives = 16/24 (66%)

Query: 113 KRSGRHRFDPFCCEVICDDGTSVK 136
           KR  ++R D FCC    +DGTSV+
Sbjct: 788 KRQEKNRLDIFCCVRGAEDGTSVQ 811


>gi|62988344 P antigen family, member 3 (prostate associated) [Homo
           sapiens]
          Length = 113

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 13/36 (36%), Positives = 17/36 (47%)

Query: 69  STSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSL 104
           S +  + G       EF+PNL P       EGQPS+
Sbjct: 78  SKTGGERGDGPNVKGEFLPNLEPVKIPEAGEGQPSV 113


>gi|115647981 glutamine and serine rich 1 [Homo sapiens]
          Length = 1735

 Score = 27.7 bits (60), Expect = 3.1
 Identities = 13/38 (34%), Positives = 22/38 (57%)

Query: 69   STSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKK 106
            S+S   D  A  TT+   P++ P++K+P  + +P  KK
Sbjct: 1463 SSSKTSDPLASKTTTTKAPSVKPKVKQPKVKAEPPPKK 1500


>gi|92091572 dedicator of cytokinesis 4 [Homo sapiens]
          Length = 1966

 Score = 27.3 bits (59), Expect = 4.1
 Identities = 11/26 (42%), Positives = 15/26 (57%)

Query: 46   PEKTFTTTPGGWLLESGRPKEMVSTS 71
            PEK    TP  W L+SG+  + +S S
Sbjct: 1757 PEKAVNPTPSSWSLDSGKEAKNMSDS 1782


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 27.3 bits (59), Expect = 4.1
 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 17/93 (18%)

Query: 60   ESGRPKEMVSTSNNKDGQALGTTSEFIPNLSPELKKPLSEGQP----------------- 102
            +SG P    ++S    G++   +S F P  + + KK   EG+P                 
Sbjct: 1678 DSGGPDGSFTSSEGSSGKSKKRSSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPK 1737

Query: 103  SLKKIILSRKKRSGRHRFDPFCCEVICDDGTSV 135
            SL K + S  K+  + + D   C      G +V
Sbjct: 1738 SLWKSVFSGYKKDKKKKADDKSCPSTPSSGATV 1770


>gi|58330892 interferon-induced protein with tetratricopeptide
           repeats 1-like [Homo sapiens]
          Length = 474

 Score = 26.9 bits (58), Expect = 5.4
 Identities = 14/42 (33%), Positives = 23/42 (54%)

Query: 97  LSEGQPSLKKIILSRKKRSGRHRFDPFCCEVICDDGTSVKLC 138
           L+E Q  L K+  + KK +   R+   C EV C++G ++  C
Sbjct: 111 LAEAQTYLDKVENTCKKFANPSRYRMECPEVDCEEGWALAKC 152


>gi|116534937 interferon-induced protein with tetratricopeptide
           repeats 1 isoform 2 [Homo sapiens]
          Length = 478

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 14/42 (33%), Positives = 22/42 (52%)

Query: 97  LSEGQPSLKKIILSRKKRSGRHRFDPFCCEVICDDGTSVKLC 138
           L+E Q  L K+    KK S   R+   C E+ C++G ++  C
Sbjct: 111 LAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKC 152


>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
          Length = 991

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 13/39 (33%), Positives = 24/39 (61%), Gaps = 3/39 (7%)

Query: 44  PMPEKTFTTTPGGWLLESGR---PKEMVSTSNNKDGQAL 79
           P PEK   ++ GG  L  GR    +++++T+ +KD Q++
Sbjct: 726 PSPEKKAKSSSGGSSLAKGRASKKQQLLATAAHKDSQSI 764


>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
           isoform 1 [Homo sapiens]
          Length = 666

 Score = 26.2 bits (56), Expect = 9.1
 Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 17/110 (15%)

Query: 10  PAIWLLLSQLLRESLAAELRGCGPRFGKHLLSYCPMPEKTFTTTPGGWLLESGRPKEMVS 69
           P +  +LS + R S A E  G  P         CP P   F+  P      S R  ++++
Sbjct: 410 PRVPDILSSVRRGSGAPEAEGPLP---------CPSPAP-FSPLPA----PSPRISDILN 455

Query: 70  TSNNKDG--QALGTTSEFIPN-LSPELKKPLSEGQPSLKKIILSRKKRSG 116
           +     G  +A G  S   P  LSP L  PLS   P +  I+ S ++ SG
Sbjct: 456 SVRRGSGTPEAEGPLSAGPPPCLSPALLGPLSSPSPRISDILNSVRRGSG 505


>gi|93102424 hypothetical protein LOC23116 [Homo sapiens]
          Length = 1720

 Score = 26.2 bits (56), Expect = 9.1
 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 11/70 (15%)

Query: 70  TSNNKDGQALGTTSEFIPNLSPELKKPLSEGQPSLKKIILSRKKRS-----GRHRFDPFC 124
           TS +KD +   +T +FIP+     K  LS+G P    +  SRK+ S         F+P C
Sbjct: 674 TSTSKDIEQF-STYDFIPSA----KLKLSQGMPVNDDLCFSRKRVSRNLFQNSRDFNPDC 728

Query: 125 CEVICDDGTS 134
              +C  GT+
Sbjct: 729 LP-LCAAGTT 737


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,240,156
Number of Sequences: 37866
Number of extensions: 304977
Number of successful extensions: 652
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 639
Number of HSP's gapped (non-prelim): 23
length of query: 139
length of database: 18,247,518
effective HSP length: 92
effective length of query: 47
effective length of database: 14,763,846
effective search space: 693900762
effective search space used: 693900762
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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