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Search of human proteins with 4504193
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504193 general transcription factor IIB [Homo sapiens]
(316 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504193 general transcription factor IIB [Homo sapiens] 629 e-180
gi|22035556 transcription initiation factor IIIB isoform 1 [Homo... 75 6e-14
gi|22035562 RNA polymerase III transcription initiation factor B... 57 2e-08
gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens] 31 1.6
gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens] 31 1.6
gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens] 30 3.7
gi|61676091 cyclin C isoform a [Homo sapiens] 29 4.8
gi|34577079 retinoblastoma-like protein 1 isoform a [Homo sapiens] 29 6.2
gi|34577077 retinoblastoma-like protein 1 isoform b [Homo sapiens] 29 6.2
gi|221554518 cyclin L2 isoform D [Homo sapiens] 29 6.2
gi|221554516 cyclin L2 isoform C [Homo sapiens] 29 6.2
gi|88758578 cyclin L2 isoform B [Homo sapiens] 29 6.2
gi|88758580 cyclin L2 isoform A [Homo sapiens] 29 6.2
gi|4758650 kinesin family member 5C [Homo sapiens] 29 6.2
gi|42475941 zinc finger protein 261 [Homo sapiens] 29 6.2
gi|4827067 zinc finger protein 261 [Homo sapiens] 29 6.2
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 28 8.2
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 28 8.2
gi|22035558 transcription initiation factor IIIB isoform 3 [Homo... 28 8.2
gi|9945320 cyclin L1 [Homo sapiens] 28 8.2
>gi|4504193 general transcription factor IIB [Homo sapiens]
Length = 316
Score = 629 bits (1621), Expect = e-180
Identities = 316/316 (100%), Positives = 316/316 (100%)
Query: 1 MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKA 60
MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKA
Sbjct: 1 MASTSRLDALPRVTCPNHPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKA 60
Query: 61 TKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKE 120
TKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKE
Sbjct: 61 TKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKE 120
Query: 121 ITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEI 180
ITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEI
Sbjct: 121 ITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEI 180
Query: 181 CAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAV 240
CAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAV
Sbjct: 181 CAVSRISKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAV 240
Query: 241 ELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLF 300
ELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLF
Sbjct: 241 ELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLF 300
Query: 301 PTDFKFDTPVDKLPQL 316
PTDFKFDTPVDKLPQL
Sbjct: 301 PTDFKFDTPVDKLPQL 316
>gi|22035556 transcription initiation factor IIIB isoform 1 [Homo
sapiens]
Length = 677
Score = 75.5 bits (184), Expect = 6e-14
Identities = 62/268 (23%), Positives = 117/268 (43%), Gaps = 28/268 (10%)
Query: 26 DYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGDSQNPLLSDGDLSTMIG 85
D GD +C CG V+ D +I V + Q + S G S+ +G
Sbjct: 17 DAARGDAVCTACGSVLEDNII--------------------VSEVQF-VESSGGGSSAVG 55
Query: 86 KGT---GAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLF 142
+ GA G + N S + + + N + I + +++ L ++ +D N F
Sbjct: 56 QFVSLDGAGKTPTLGGGFHVNLGKESRA-QTLQNGRRHIHHLGNQLQLNQHCLDTAFNFF 114
Query: 143 KQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKAL 202
K + +GR + +ACLY+ CR EG P ++ + +++ +G+ F L+ + L
Sbjct: 115 KMAVSRHLTRGRKMAHVIAACLYLVCRTEGTPHMLLDLSDLLQVNVYVLGKTFLLLAREL 174
Query: 203 ETSVDLITTGDFMSRFCSNLCLPK---QVQMAATHIARKAVELDLVPGRSPISVAAAAIY 259
+ I ++ RF L + +V M A + ++ + GR P + AA+
Sbjct: 175 CINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQRMKRDWMHTGRRPSGLCGAALL 234
Query: 260 MASQASAEKRTQKEIGDIAGVADVTIRQ 287
+A++ +RT KE+ + V + T+R+
Sbjct: 235 VAARMHDFRRTVKEVISVVKVCESTLRK 262
>gi|22035562 RNA polymerase III transcription initiation factor BRF2
[Homo sapiens]
Length = 419
Score = 57.0 bits (136), Expect = 2e-08
Identities = 56/272 (20%), Positives = 99/272 (36%), Gaps = 58/272 (21%)
Query: 12 RVTCPNHPDAILVED--YRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKATKDPSRVGD 69
R CP+ LVED Y ++C +CG VV + V+ TFS++ ++ +
Sbjct: 4 RGRCPDCGSTELVEDSHYSQSQLVCSDCGCVVTEGVLTT-----TFSDEGNLREVT---- 54
Query: 70 SQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRIN 129
+ S +N + S R + + + + +
Sbjct: 55 --------------------------YSRSTGENEQVSRSQQRGL----RRVRDLCRVLQ 84
Query: 130 LPRNIVDRTNNLFKQVYEQKSLKG---RANDAIASACLYIACRQEGVPRTFKEICAVSRI 186
LP D ++Q Y ++ + + + C+ I CRQ P T IC +
Sbjct: 85 LPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCVLITCRQHNWPLTMGAICTLLYA 144
Query: 187 SKKEIGRCFKLILKALETSVDLITTGDFMSRFCSNLCL-------------PKQVQMAAT 233
+ I+K L V + + + +CS+ L K+ ++ T
Sbjct: 145 DLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKLFQASPSVPAKYVEDKEKMLSRT 204
Query: 234 -HIARKAVELDLVPGRSPISVAAAAIYMASQA 264
+ A E LV GR P+ V AA ++A Q+
Sbjct: 205 MQLVELANETWLVTGRHPLPVITAATFLAWQS 236
>gi|157694494 MYB binding protein 1a isoform 1 [Homo sapiens]
Length = 1332
Score = 30.8 bits (68), Expect = 1.6
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 152 KGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKK---EIGRCFKLILKAL----ET 204
K R AIA L +A +++ PR +KE+ + + CF+L+ AL +
Sbjct: 260 KDRKLPAIALDLLRLALKEDKFPRFWKEVVEQGLLKMQFWPASYLCFRLLGAALPLLTKE 319
Query: 205 SVDLITTGDFMSRFCSNLC---LPKQVQMA 231
+ L+ GD + + ++C LPKQ + A
Sbjct: 320 QLHLVMQGDVIRHYGEHVCTAKLPKQFKFA 349
>gi|157694492 MYB binding protein 1a isoform 2 [Homo sapiens]
Length = 1328
Score = 30.8 bits (68), Expect = 1.6
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 10/90 (11%)
Query: 152 KGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKK---EIGRCFKLILKAL----ET 204
K R AIA L +A +++ PR +KE+ + + CF+L+ AL +
Sbjct: 260 KDRKLPAIALDLLRLALKEDKFPRFWKEVVEQGLLKMQFWPASYLCFRLLGAALPLLTKE 319
Query: 205 SVDLITTGDFMSRFCSNLC---LPKQVQMA 231
+ L+ GD + + ++C LPKQ + A
Sbjct: 320 QLHLVMQGDVIRHYGEHVCTAKLPKQFKFA 349
>gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens]
Length = 471
Score = 29.6 bits (65), Expect = 3.7
Identities = 49/201 (24%), Positives = 75/201 (37%), Gaps = 33/201 (16%)
Query: 85 GKGTGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQ 144
G+G S+ E RR +SS+D A++ A E + LFK+
Sbjct: 42 GQGREGRSWGEGPRGPGLGRRDLSSADPAVLGATMESRCYGCAVKF---------TLFKK 92
Query: 145 VYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEIC----------AVSRISKKEIGRC 194
Y K+ GR A S CL + T +++C + + SK +
Sbjct: 93 EYGCKNC-GR---AFCSGCLSFSAAVPRTGNTQQKVCKQCHEVLTRGSSANASKWSPPQN 148
Query: 195 FKLILKALETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVE--LDLVPGRSPIS 252
+K + ALE T+ + L +Q QM A +AR E LVP ++ I
Sbjct: 149 YKKRVAALEAKQKPSTS--------QSQGLTRQDQMIAERLARLRQENKPKLVPSQAEIE 200
Query: 253 VAAAAIYMASQASAEKRTQKE 273
AA+ Q S + E
Sbjct: 201 ARLAALKDERQGSIPSTQEME 221
>gi|61676091 cyclin C isoform a [Homo sapiens]
Length = 283
Score = 29.3 bits (64), Expect = 4.8
Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 2/77 (2%)
Query: 121 ITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQE--GVPRTFK 178
I + + + L + ++ FK+ Y + SLK +A C+++A + E GV +
Sbjct: 48 IQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTR 107
Query: 179 EICAVSRISKKEIGRCF 195
I A + + K F
Sbjct: 108 LIAAATSVLKTRFSYAF 124
>gi|34577079 retinoblastoma-like protein 1 isoform a [Homo sapiens]
Length = 1068
Score = 28.9 bits (63), Expect = 6.2
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 117 AFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRT 176
A + + + +NL + F + SL+G +A + LY+ACR+ +P
Sbjct: 17 AGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACS-LYVACRKSIIPTV 75
Query: 177 FKEICAVSRISKKEIGRCFKLIL 199
K I + +S I R KL L
Sbjct: 76 GKGIMEGNCVSLTRILRSAKLSL 98
>gi|34577077 retinoblastoma-like protein 1 isoform b [Homo sapiens]
Length = 1014
Score = 28.9 bits (63), Expect = 6.2
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 117 AFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRT 176
A + + + +NL + F + SL+G +A + LY+ACR+ +P
Sbjct: 17 AGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACS-LYVACRKSIIPTV 75
Query: 177 FKEICAVSRISKKEIGRCFKLIL 199
K I + +S I R KL L
Sbjct: 76 GKGIMEGNCVSLTRILRSAKLSL 98
>gi|221554518 cyclin L2 isoform D [Homo sapiens]
Length = 227
Score = 28.9 bits (63), Expect = 6.2
Identities = 13/56 (23%), Positives = 30/56 (53%)
Query: 128 INLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAV 183
+ LP+ + LF++ + KS + + ++ AC+++A + E PR +++ V
Sbjct: 92 LRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINV 147
>gi|221554516 cyclin L2 isoform C [Homo sapiens]
Length = 236
Score = 28.9 bits (63), Expect = 6.2
Identities = 13/56 (23%), Positives = 30/56 (53%)
Query: 128 INLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAV 183
+ LP+ + LF++ + KS + + ++ AC+++A + E PR +++ V
Sbjct: 92 LRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINV 147
>gi|88758578 cyclin L2 isoform B [Homo sapiens]
Length = 226
Score = 28.9 bits (63), Expect = 6.2
Identities = 13/56 (23%), Positives = 30/56 (53%)
Query: 128 INLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAV 183
+ LP+ + LF++ + KS + + ++ AC+++A + E PR +++ V
Sbjct: 92 LRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINV 147
>gi|88758580 cyclin L2 isoform A [Homo sapiens]
Length = 520
Score = 28.9 bits (63), Expect = 6.2
Identities = 13/56 (23%), Positives = 30/56 (53%)
Query: 128 INLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAV 183
+ LP+ + LF++ + KS + + ++ AC+++A + E PR +++ V
Sbjct: 92 LRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMACVHLASKIEEAPRRIRDVINV 147
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 28.9 bits (63), Expect = 6.2
Identities = 26/108 (24%), Positives = 43/108 (39%), Gaps = 4/108 (3%)
Query: 146 YEQKSL----KGRANDAIASACLYIACRQEGVPRTFKEICAVSRISKKEIGRCFKLILKA 201
Y+QKS K RAN+ + R ++ +S KK L+LK
Sbjct: 498 YDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKD 557
Query: 202 LETSVDLITTGDFMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRS 249
L +I T D + N + ++ MA +I++ E+ + RS
Sbjct: 558 LGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRS 605
>gi|42475941 zinc finger protein 261 [Homo sapiens]
Length = 1370
Score = 28.9 bits (63), Expect = 6.2
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 167 ACRQEGVPRTFKEICAVSRISKKEIGR-----CFKLILKALETSVDLITTGDFMSRFCSN 221
A +++G+P+ F ++ SKK G+ C K I ++ V +G FC++
Sbjct: 324 AYQRKGLPQLFCSSSCLTTFSKKPSGKKTCTFCKKEIWNTKDSVVAQTGSGGSFHEFCTS 383
Query: 222 LCL 224
+CL
Sbjct: 384 VCL 386
>gi|4827067 zinc finger protein 261 [Homo sapiens]
Length = 1370
Score = 28.9 bits (63), Expect = 6.2
Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 167 ACRQEGVPRTFKEICAVSRISKKEIGR-----CFKLILKALETSVDLITTGDFMSRFCSN 221
A +++G+P+ F ++ SKK G+ C K I ++ V +G FC++
Sbjct: 324 AYQRKGLPQLFCSSSCLTTFSKKPSGKKTCTFCKKEIWNTKDSVVAQTGSGGSFHEFCTS 383
Query: 222 LCL 224
+CL
Sbjct: 384 VCL 386
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 28.5 bits (62), Expect = 8.2
Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 2/49 (4%)
Query: 56 SNDKATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNR 104
+N +T+D VG S + + S +T T ++S GN YQNR
Sbjct: 628 TNSSSTQDSMEVGHSHHSMTSLSSSTT--SSSTSSSSTGNQGNQAYQNR 674
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 28.5 bits (62), Expect = 8.2
Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 2/49 (4%)
Query: 56 SNDKATKDPSRVGDSQNPLLSDGDLSTMIGKGTGAASFDEFGNSKYQNR 104
+N +T+D VG S + + S +T T ++S GN YQNR
Sbjct: 637 TNSSSTQDSMEVGHSHHSMTSLSSSTT--SSSTSSSSTGNQGNQAYQNR 683
>gi|22035558 transcription initiation factor IIIB isoform 3 [Homo
sapiens]
Length = 473
Score = 28.5 bits (62), Expect = 8.2
Identities = 13/41 (31%), Positives = 24/41 (58%)
Query: 247 GRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQ 287
GR P + AA+ +A++ +RT KE+ + V + T+R+
Sbjct: 18 GRRPSGLCGAALLVAARMHDFRRTVKEVISVVKVCESTLRK 58
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 28.5 bits (62), Expect = 8.2
Identities = 14/56 (25%), Positives = 28/56 (50%)
Query: 128 INLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAV 183
+ LP+ + LF + + KS + + +A AC+ +A + E PR +++ V
Sbjct: 97 LRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACINLASKIEEAPRRIRDVINV 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,927,929
Number of Sequences: 37866
Number of extensions: 432512
Number of successful extensions: 915
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 893
Number of HSP's gapped (non-prelim): 30
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.