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Search of human proteins with 4504025
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504025 glutaredoxin (thioltransferase) [Homo sapiens]
(106 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169646776 glutaredoxin (thioltransferase) [Homo sapiens] 215 5e-57
gi|4504025 glutaredoxin (thioltransferase) [Homo sapiens] 215 5e-57
gi|37537704 glutaredoxin 2 isoform 2 [Homo sapiens] 62 1e-10
gi|21361507 glutaredoxin 2 isoform 1 [Homo sapiens] 62 1e-10
gi|42516576 glutaredoxin 5 [Homo sapiens] 47 3e-06
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens] 38 0.002
gi|122937349 glutaredoxin, cysteine rich 1 [Homo sapiens] 32 0.085
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 30 0.32
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 30 0.32
gi|95113651 glutaredoxin 3 [Homo sapiens] 30 0.32
gi|81295407 acyl-Coenzyme A thioesterase 2, mitochondrial isofor... 30 0.55
gi|4506127 phosphoribosyl pyrophosphate synthetase 1 [Homo sapiens] 28 1.6
gi|4506129 phosphoribosyl pyrophosphate synthetase 2 isoform 2 [... 28 1.6
gi|28557709 phosphoribosyl pyrophosphate synthetase 1-like 1 [Ho... 28 1.6
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 28 2.1
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 28 2.1
gi|22218339 hypothetical protein LOC90362 [Homo sapiens] 27 3.6
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 27 4.6
gi|95147335 inositol 1,4,5-triphosphate receptor, type 2 [Homo s... 26 6.1
gi|122937215 prospero homeobox 2 [Homo sapiens] 26 6.1
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 26 7.9
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 26 7.9
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 26 7.9
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 26 7.9
gi|4506321 protein tyrosine phosphatase, receptor type, N precur... 26 7.9
>gi|169646776 glutaredoxin (thioltransferase) [Homo sapiens]
Length = 106
Score = 215 bits (548), Expect = 5e-57
Identities = 106/106 (100%), Positives = 106/106 (100%)
Query: 1 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY 60
MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
Sbjct: 1 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY 60
Query: 61 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ 106
LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
Sbjct: 61 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ 106
>gi|4504025 glutaredoxin (thioltransferase) [Homo sapiens]
Length = 106
Score = 215 bits (548), Expect = 5e-57
Identities = 106/106 (100%), Positives = 106/106 (100%)
Query: 1 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY 60
MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY
Sbjct: 1 MAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDY 60
Query: 61 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ 106
LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ
Sbjct: 61 LQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ 106
>gi|37537704 glutaredoxin 2 isoform 2 [Homo sapiens]
Length = 164
Score = 61.6 bits (148), Expect = 1e-10
Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Query: 15 VVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVF 74
VV+F K +C YC A+++ + + + V++ + N+ QD L ++TG RTVPR+F
Sbjct: 69 VVIFSKTSCSYCTMAKKLFHDMNVNY---KVVELDLLEYGNQFQDALYKMTGERTVPRIF 125
Query: 75 IGKDCIGGCSDLVSLQQSGELLTRLKQ 101
+ IGG +D L + G+LL + Q
Sbjct: 126 VNGTFIGGATDTHRLHKEGKLLPLVHQ 152
>gi|21361507 glutaredoxin 2 isoform 1 [Homo sapiens]
Length = 165
Score = 61.6 bits (148), Expect = 1e-10
Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Query: 15 VVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVF 74
VV+F K +C YC A+++ + + + V++ + N+ QD L ++TG RTVPR+F
Sbjct: 70 VVIFSKTSCSYCTMAKKLFHDMNVNY---KVVELDLLEYGNQFQDALYKMTGERTVPRIF 126
Query: 75 IGKDCIGGCSDLVSLQQSGELLTRLKQ 101
+ IGG +D L + G+LL + Q
Sbjct: 127 VNGTFIGGATDTHRLHKEGKLLPLVHQ 153
>gi|42516576 glutaredoxin 5 [Homo sapiens]
Length = 157
Score = 47.0 bits (110), Expect = 3e-06
Identities = 26/102 (25%), Positives = 57/102 (55%), Gaps = 4/102 (3%)
Query: 4 EFVNCKIQPGKVVVFIK--PTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYL 61
E ++ ++ KVVVF+K P P C + ++ L + G+ ++ + E++ +
Sbjct: 43 EQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRL-HGVRDYAAYNVLDDP-ELRQGI 100
Query: 62 QQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIG 103
+ + T+P+V++ + +GGC L+ + Q+G+L+ LK++G
Sbjct: 101 KDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLG 142
>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
Length = 649
Score = 38.1 bits (87), Expect = 0.002
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 15 VVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVF 74
VV+F + TC C +++ L + +LE + T ++ L +L +P VF
Sbjct: 68 VVIFSRSTCTRCTEVKKLFKSLCVPYFVLE---LDQTEDGRALEGTLSELAAETDLPVVF 124
Query: 75 IGKDCIGGCSDLVSLQQSGELLTRLKQIG 103
+ + IGG + Q G L LK G
Sbjct: 125 VKQRKIGGHGPTLKAYQEGRLQKLLKMNG 153
>gi|122937349 glutaredoxin, cysteine rich 1 [Homo sapiens]
Length = 290
Score = 32.3 bits (72), Expect = 0.085
Identities = 16/51 (31%), Positives = 31/51 (60%)
Query: 56 EIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQIGALQ 106
E+ + ++++ A ++P VFI +GG ++S+ +SGEL L +I +Q
Sbjct: 184 ELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGELQDILTKIERVQ 234
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 30.4 bits (67), Expect = 0.32
Identities = 12/49 (24%), Positives = 24/49 (48%)
Query: 27 RRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFI 75
+ +++++ Q L F+ + H N+ Q+YL+ TG T + I
Sbjct: 3863 QNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIII 3911
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 30.4 bits (67), Expect = 0.32
Identities = 12/49 (24%), Positives = 24/49 (48%)
Query: 27 RRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFI 75
+ +++++ Q L F+ + H N+ Q+YL+ TG T + I
Sbjct: 3868 QNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIII 3916
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 30.4 bits (67), Expect = 0.32
Identities = 16/78 (20%), Positives = 40/78 (51%), Gaps = 6/78 (7%)
Query: 23 CPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGG 82
C + ++ EIL+ ++ + ++ E++ L+ + T P++++ + +GG
Sbjct: 261 CGFSKQILEILNSTGVEYETFDILE------DEEVRQGLKAYSNWPTYPQLYVKGELVGG 314
Query: 83 CSDLVSLQQSGELLTRLK 100
+ L+++GELL L+
Sbjct: 315 LDIVKELKENGELLPILR 332
Score = 27.3 bits (59), Expect = 2.7
Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 20 KPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDC 79
+P C + ++ EIL + I+ + E++ L+ + T P++++ +
Sbjct: 156 EPRCGFSKQMVEILHKHNIQFSSFDIFS------DEEVRQGLKAYSSWPTYPQLYVSGEL 209
Query: 80 IGGCSDLVSLQQSGELLT 97
IGG + L+ S EL T
Sbjct: 210 IGGLDIIKELEASEELDT 227
>gi|81295407 acyl-Coenzyme A thioesterase 2, mitochondrial isoform
a [Homo sapiens]
Length = 448
Score = 29.6 bits (65), Expect = 0.55
Identities = 12/35 (34%), Positives = 21/35 (60%)
Query: 35 QLPIKQGLLEFVDITATNHTNEIQDYLQQLTGART 69
Q P KQG+ + ++ H N ++D L+++ GA T
Sbjct: 27 QNPKKQGIFHIHEACSSIHVNHVRDKLREIVGAST 61
>gi|4506127 phosphoribosyl pyrophosphate synthetase 1 [Homo sapiens]
Length = 318
Score = 28.1 bits (61), Expect = 1.6
Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 8 CKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLL-EFVDITATNHTNEIQDYLQQLTG 66
CKI V + P PY R+ ++ S+ PI L+ + + +H + + Q+ G
Sbjct: 77 CKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQG 136
Query: 67 ARTVP 71
+P
Sbjct: 137 FFDIP 141
>gi|4506129 phosphoribosyl pyrophosphate synthetase 2 isoform 2
[Homo sapiens]
Length = 318
Score = 28.1 bits (61), Expect = 1.6
Identities = 16/65 (24%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 8 CKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLL-EFVDITATNHTNEIQDYLQQLTG 66
CKI V + P PY R+ ++ S+ PI L+ + + +H + + Q+ G
Sbjct: 77 CKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQG 136
Query: 67 ARTVP 71
+P
Sbjct: 137 FFDIP 141
>gi|28557709 phosphoribosyl pyrophosphate synthetase 1-like 1 [Homo
sapiens]
Length = 318
Score = 28.1 bits (61), Expect = 1.6
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 1/65 (1%)
Query: 8 CKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLL-EFVDITATNHTNEIQDYLQQLTG 66
CKI V + P PY R+ ++ S+ PI L+ + I +H + + Q+ G
Sbjct: 77 CKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAGADHIITMDLHASQIQG 136
Query: 67 ARTVP 71
+P
Sbjct: 137 FFDIP 141
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 27.7 bits (60), Expect = 2.1
Identities = 12/33 (36%), Positives = 17/33 (51%)
Query: 47 DITATNHTNEIQDYLQQLTGARTVPRVFIGKDC 79
DI+ T +NE+ LTG+ T P F+ C
Sbjct: 272 DISDTQASNELSRIANSLTGSNTAPGSFLFSSC 304
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 27.7 bits (60), Expect = 2.1
Identities = 12/33 (36%), Positives = 17/33 (51%)
Query: 47 DITATNHTNEIQDYLQQLTGARTVPRVFIGKDC 79
DI+ T +NE+ LTG+ T P F+ C
Sbjct: 541 DISDTQASNELSRIANSLTGSNTAPGSFLFSSC 573
>gi|22218339 hypothetical protein LOC90362 [Homo sapiens]
Length = 370
Score = 26.9 bits (58), Expect = 3.6
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 1/29 (3%)
Query: 2 AQEFVNCKIQPGKVVVFIK-PTCPYCRRA 29
+QE +N K +P K V K P CP +RA
Sbjct: 64 SQEVINAKQEPVKPAVLAKPPVCPAAKRA 92
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 26.6 bits (57), Expect = 4.6
Identities = 17/63 (26%), Positives = 29/63 (46%)
Query: 42 LLEFVDITATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRLKQ 101
LLE D A +H + + + L+ L T+P + G +DL L+ S L + +
Sbjct: 1293 LLEHQDCIAPDHQDPLHELLEDLGELPTIPDLIGESIAADGHTDLSKLEVSLTLTNKFEG 1352
Query: 102 IGA 104
+ A
Sbjct: 1353 LEA 1355
>gi|95147335 inositol 1,4,5-triphosphate receptor, type 2 [Homo
sapiens]
Length = 2701
Score = 26.2 bits (56), Expect = 6.1
Identities = 15/50 (30%), Positives = 23/50 (46%), Gaps = 3/50 (6%)
Query: 36 LPIKQGLLEFVDITATNHTNEIQDYLQ---QLTGARTVPRVFIGKDCIGG 82
+ I Q +L F+ + NH E+Q++L+ T V DCI G
Sbjct: 1915 IAIMQPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICG 1964
>gi|122937215 prospero homeobox 2 [Homo sapiens]
Length = 592
Score = 26.2 bits (56), Expect = 6.1
Identities = 12/32 (37%), Positives = 15/32 (46%)
Query: 12 PGKVVVFIKPTCPYCRRAQEILSQLPIKQGLL 43
PG + P CP R ++ LP QGLL
Sbjct: 84 PGNAQAGVSPRCPKKARERKRKQNLPTPQGLL 115
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 25.8 bits (55), Expect = 7.9
Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 40 QGLLEFVDITATNHTNEIQDYLQQLTGAR---TVPRVFIGKDC 79
QG ITA + N++QD +Q+ + VP + +G C
Sbjct: 76 QGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKC 118
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 25.8 bits (55), Expect = 7.9
Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 40 QGLLEFVDITATNHTNEIQDYLQQLTGAR---TVPRVFIGKDC 79
QG ITA + N++QD +Q+ + VP + +G C
Sbjct: 76 QGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKC 118
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 25.8 bits (55), Expect = 7.9
Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 40 QGLLEFVDITATNHTNEIQDYLQQLTGAR---TVPRVFIGKDC 79
QG ITA + N++QD +Q+ + VP + +G C
Sbjct: 76 QGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKC 118
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 25.8 bits (55), Expect = 7.9
Identities = 13/43 (30%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 40 QGLLEFVDITATNHTNEIQDYLQQLTGAR---TVPRVFIGKDC 79
QG ITA + N++QD +Q+ + VP + +G C
Sbjct: 76 QGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKC 118
>gi|4506321 protein tyrosine phosphatase, receptor type, N precursor
[Homo sapiens]
Length = 979
Score = 25.8 bits (55), Expect = 7.9
Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Query: 5 FVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDIT 49
F C++ G+ ++ T P +R Q +L QL + QGL D+T
Sbjct: 59 FGQCQVGVGQARPLLQVTSPVLQRLQGVLRQL-MSQGLSWHDDLT 102
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,629,964
Number of Sequences: 37866
Number of extensions: 121718
Number of successful extensions: 287
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 267
Number of HSP's gapped (non-prelim): 26
length of query: 106
length of database: 18,247,518
effective HSP length: 76
effective length of query: 30
effective length of database: 15,369,702
effective search space: 461091060
effective search space used: 461091060
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.