Guide to the Human Genome
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Search of human proteins with 4503591

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503591 erythropoietin receptor precursor [Homo sapiens]
         (508 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503591 erythropoietin receptor precursor [Homo sapiens]          1050   0.0  
gi|29171682 interleukin 9 receptor precursor [Homo sapiens]            74   2e-13
gi|4885491 myeloproliferative leukemia virus oncogene precursor ...    61   2e-09
gi|31083174 interleukin 21 receptor precursor [Homo sapiens]           57   4e-08
gi|11141869 interleukin 21 receptor precursor [Homo sapiens]           57   4e-08
gi|31083180 interleukin 21 receptor precursor [Homo sapiens]           57   4e-08
gi|4506107 prolactin receptor [Homo sapiens]                           56   7e-08
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    55   2e-07
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]              54   3e-07
gi|28610151 interleukin 7 receptor precursor [Homo sapiens]            54   4e-07
gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo sapi...    52   2e-06
gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo sapi...    51   2e-06
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H...    47   3e-05
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H...    47   3e-05
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]      44   3e-04
gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]        41   0.003
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s...    41   0.003
gi|189083786 leukemia inhibitory factor receptor precursor [Homo...    41   0.003
gi|51093381 leptin receptor isoform 3 [Homo sapiens]                   40   0.007
gi|51093379 leptin receptor isoform 2 [Homo sapiens]                   40   0.007
gi|40254464 leptin receptor isoform 1 [Homo sapiens]                   40   0.007
gi|21361766 zinc finger protein 692 isoform 2 [Homo sapiens]           39   0.011
gi|209862873 zinc finger protein 692 isoform 1 [Homo sapiens]          39   0.011
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi...    39   0.015
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ...    37   0.032
gi|5031785 interleukin 12 receptor, beta 1 isoform 1 precursor [...    36   0.072
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      35   0.12 
gi|149944516 tet oncogene family member 3 [Homo sapiens]               35   0.21 
gi|115430248 gp130-like monocyte receptor [Homo sapiens]               35   0.21 
gi|32967311 ephrin receptor EphA2 [Homo sapiens]                       34   0.28 

>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
          Length = 508

 Score = 1050 bits (2715), Expect = 0.0
 Identities = 508/508 (100%), Positives = 508/508 (100%)

Query: 1   MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL 60
           MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL
Sbjct: 1   MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL 60

Query: 61  VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL 120
           VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL
Sbjct: 61  VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL 120

Query: 121 ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY 180
           ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY
Sbjct: 121 ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY 180

Query: 181 EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV 240
           EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV
Sbjct: 181 EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV 240

Query: 241 SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH 300
           SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH
Sbjct: 241 SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH 300

Query: 301 KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG 360
           KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG
Sbjct: 301 KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG 360

Query: 361 SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS 420
           SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS
Sbjct: 361 SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS 420

Query: 421 AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL 480
           AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL
Sbjct: 421 AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL 480

Query: 481 SDGPYSNPYENSLIPAAEPLPPSYVACS 508
           SDGPYSNPYENSLIPAAEPLPPSYVACS
Sbjct: 481 SDGPYSNPYENSLIPAAEPLPPSYVACS 508


>gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
          Length = 521

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 106/416 (25%), Positives = 156/416 (37%), Gaps = 92/416 (22%)

Query: 52  CFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPT 111
           C T  +  + C W  A   G G             PW L   +QAP         C L  
Sbjct: 56  CLTNNILRIDCHWS-APELGQG-----------SSPWLLFTSNQAPGGTHK----CILRG 99

Query: 112 ADTSSFVPLE-LRVTAASGAPRYHRVIHINEVVLL-------------DAPVGLVARLAD 157
           ++ +  +P E + V + +    +H  +   E V L             D P  L + ++ 
Sbjct: 100 SECTVVLPPEAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNIS- 158

Query: 158 ESGHVVLRW-LPPPETPMTSHIRYEVDVSAGNGAGS-VQRVEILEGRTECVLSNLRGRTR 215
            SGH +L W + P   PMT+ + YE+       A    Q  + + G T  +L        
Sbjct: 159 -SGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPG 217

Query: 216 YTFAVRARMA----------EPSFGGFWSAWSEPVSLLTPSDLDPLILTL-----SLILV 260
           +    R R+           E  + G WS WS+PV    P    PLI        +L+ V
Sbjct: 218 FIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAV 277

Query: 261 VILVLLT----VLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWL-YQNDGCL 315
            I +LLT    +L  LS R  +K+  +  +PSP   F+ L++ H GNFQ W+     G L
Sbjct: 278 SIFLLLTGPTYLLFKLSPR--VKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVL 335

Query: 316 WWSPCT--------PFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQD- 366
               C         P  ++  A L     R W ++   E   + EGP     G+  ++D 
Sbjct: 336 LSQDCAGTPQGALEPCVQEATALLTCGPARPWKSVALEE---EQEGPGTRLPGNLSSEDV 392

Query: 367 -------------TYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSA 409
                         YL  + W     P S   P P  S       EGS +SS SS+
Sbjct: 393 LPAGCTEWRVQTLAYLPQEDWA----PTSLTRPAPPDS-------EGSRSSSSSSS 437


>gi|4885491 myeloproliferative leukemia virus oncogene precursor
           [Homo sapiens]
          Length = 635

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 67/283 (23%), Positives = 99/283 (34%), Gaps = 62/283 (21%)

Query: 16  CLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPG 75
           CLLLA      P NL   +  S+   L A   E L CF+   EDL CFW+E  +A    G
Sbjct: 12  CLLLA------PQNLA--QVSSQDVSLLASDSEPLKCFSRTFEDLTCFWDEEEAA--PSG 61

Query: 76  NYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLP-TADTSSFVPLELRV-TAASGAPRY 133
            Y   Y    E  + C L          R+ C  P   +   F PL L V        R 
Sbjct: 62  TYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFPLHLWVKNVFLNQTRT 121

Query: 134 HRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSV 193
            RV+ ++ V L   P  + A    + G + + W   P   ++  +RYE+     +   S 
Sbjct: 122 QRVLFVDSVGLPAPPSIIKAMGGSQPGELQISW-EEPAPEISDFLRYELRYGPRDPKNST 180

Query: 194 --QRVEILEGRTEC---------------------------------------------- 205
               ++++   T C                                              
Sbjct: 181 GPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDGPKQTSPSREASALTAEGGS 240

Query: 206 -VLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD 247
            ++S L+    Y   +R+     S GG W +WS PV++  P D
Sbjct: 241 CLISGLQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTVDLPGD 283



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 67/254 (26%), Positives = 111/254 (43%), Gaps = 25/254 (9%)

Query: 50  LLCFTERLEDLVCFWEE---AASAGVGPGNYSFSYQLEDEP-WKLCRLHQA--PTARGAV 103
           L CFT  L+++ C W++   A+S G    + +     +  P W+ C   +   P  +   
Sbjct: 289 LQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCPRDRYPIWENCEEEEKTNPGLQTPQ 348

Query: 104 RFWCSLPTADTSSFVPLELRVTAASGAPRYH--RVIHINEVVLLDAPVGLVARLADESGH 161
              C   + +  S + + + VT A G    +      I++ V L  P      ++  SGH
Sbjct: 349 FSRCHFKSRN-DSIIHILVEVTTAPGTVHSYLGSPFWIHQAVRLPTPNLHWREIS--SGH 405

Query: 162 VVLRWLPPPETPMTS---HIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTF 218
           + L W  P           +RY      G G    + +E   G     L  LR R+RY  
Sbjct: 406 LELEWQHPSSWAAQETCYQLRY-----TGEGHQDWKVLEPPLGARGGTLE-LRPRSRYRL 459

Query: 219 AVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL-----S 273
            +RAR+  P++ G WS+WS+P  + T ++   + L  +L LV+ L  +  L LL     +
Sbjct: 460 QLRARLNGPTYQGPWSSWSDPTRVETATETAWISLVTALHLVLGLSAVLGLLLLRWQFPA 519

Query: 274 HRRALKQKIWPGIP 287
           H R L+  +WP +P
Sbjct: 520 HYRRLRHALWPSLP 533


>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)

Query: 46  GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101
           G  +L+C+T+ L+ ++C  E      + P   + ++Q + E  K     C LH++     
Sbjct: 19  GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75

Query: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
              + C +      +     + +T  SG         +    +  AP   V      SG 
Sbjct: 76  HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133

Query: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213
             + W    E P    +   ++YE+         +V   +++  ++ R+  +L    R  
Sbjct: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193

Query: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272
           + Y   VRA  M   S+ G WS WS+PV   T S+         L+L+++LV++ + A  
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253

Query: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321
           S +      L +KIW  +PSPE  F  L+    G+F+ W+         +P T       
Sbjct: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304

Query: 322 PFTEDPPASLEVLS 335
           P++ + P++LEV S
Sbjct: 305 PWSPEVPSTLEVYS 318


>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)

Query: 46  GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101
           G  +L+C+T+ L+ ++C  E      + P   + ++Q + E  K     C LH++     
Sbjct: 19  GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75

Query: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
              + C +      +     + +T  SG         +    +  AP   V      SG 
Sbjct: 76  HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133

Query: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213
             + W    E P    +   ++YE+         +V   +++  ++ R+  +L    R  
Sbjct: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193

Query: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272
           + Y   VRA  M   S+ G WS WS+PV   T S+         L+L+++LV++ + A  
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253

Query: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321
           S +      L +KIW  +PSPE  F  L+    G+F+ W+         +P T       
Sbjct: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304

Query: 322 PFTEDPPASLEVLS 335
           P++ + P++LEV S
Sbjct: 305 PWSPEVPSTLEVYS 318


>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
          Length = 538

 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)

Query: 46  GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101
           G  +L+C+T+ L+ ++C  E      + P   + ++Q + E  K     C LH++     
Sbjct: 19  GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75

Query: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
              + C +      +     + +T  SG         +    +  AP   V      SG 
Sbjct: 76  HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133

Query: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213
             + W    E P    +   ++YE+         +V   +++  ++ R+  +L    R  
Sbjct: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193

Query: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272
           + Y   VRA  M   S+ G WS WS+PV   T S+         L+L+++LV++ + A  
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253

Query: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321
           S +      L +KIW  +PSPE  F  L+    G+F+ W+         +P T       
Sbjct: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304

Query: 322 PFTEDPPASLEVLS 335
           P++ + P++LEV S
Sbjct: 305 PWSPEVPSTLEVYS 318


>gi|4506107 prolactin receptor [Homo sapiens]
          Length = 622

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 65/299 (21%), Positives = 114/299 (38%), Gaps = 24/299 (8%)

Query: 47  PEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFW 106
           PE   C +   E   C+W      G+ P NYS +Y  E E      +H+ P         
Sbjct: 31  PEIFKCRSPNKETFTCWWRPGTDGGL-PTNYSLTYHREGETL----MHECPDYITGGPNS 85

Query: 107 CSLPTADTSSFVPLELRVTAAS---GAPRYHRVIHINEVVLLDAPVGLVARLA---DESG 160
           C      TS +    + V A +    +      + +  +V  D P+ L   +    D   
Sbjct: 86  CHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKP 145

Query: 161 HVVLRWLPPPETPMTSH---IRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYT 217
           ++ ++W PP    + +    + YE+ +     A     +     +TE  + +L    +Y 
Sbjct: 146 YLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAE--WEIHFAGQQTEFKILSLHPGQKYL 203

Query: 218 FAVRARMAEPSFGGFWSAWSEPVSLLTPSDL---DPLILTLSLILVVILVLLTVLALLSH 274
             VR +       G+WSAWS    +  PSD    D  +     +L  ++ L+ V A+   
Sbjct: 204 VQVRCKPDH----GYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALK 259

Query: 275 RRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEV 333
             ++   I+P +P P+ +        KG  +  L    GC  + P + + +     LEV
Sbjct: 260 GYSMVTCIFPPVPGPKIKGFDAHLLEKGKSE-ELLSALGCQDFPPTSDYEDLLVEYLEV 317


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 100/433 (23%), Positives = 150/433 (34%), Gaps = 68/433 (15%)

Query: 47  PEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAV--- 103
           P+ L CF +    L C WE             F     D   + C    +P  R  +   
Sbjct: 245 PQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEEC----SPVLREGLGSL 300

Query: 104 --RFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
             R  C +P  D ++     + V            ++I       AP  L   +  +   
Sbjct: 301 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQM-----APPSL--NVTKDGDS 353

Query: 162 VVLRW----LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYT 217
             LRW    +       T  I+Y  D +    +    + E L+      L  L   TRY 
Sbjct: 354 YSLRWETMKMRYEHIDHTFEIQYRKDTATWKDS----KTETLQNAHSMALPALEPSTRYW 409

Query: 218 FAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRA 277
             VR R +   + G WS WSE  S  T S L   +L L +I + I VLL +     +   
Sbjct: 410 ARVRVRTSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYR 469

Query: 278 LKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSP--CTPFTEDPPASLEVLS 335
           L++K    IP+P                  L+QN     W P   + FT   P       
Sbjct: 470 LRRKWEEKIPNPSKSH--------------LFQNGSAELWPPGSMSAFTSGSPP-----H 510

Query: 336 ERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIV 395
           +  WG+      G       + PVG   ++ + L ++      +PPS    GP  +    
Sbjct: 511 QGPWGSRFPELEG-------VFPVGFGDSEVSPLTIEDPKHVCDPPS----GPDTTPAAS 559

Query: 396 AMDEGSEASSCSSALASKPSPEGASAASFEYT---ILDPSSQLLRPWTLCPELP------ 446
            +      S      A+  +PE   A+SF++    +  P S+ L      PE P      
Sbjct: 560 DLPTEQPPSPQPGPPAASHTPE-KQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQ 618

Query: 447 --PTPPHLKYLYL 457
             P P  L+YL L
Sbjct: 619 KSPPPGSLEYLCL 631


>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
          Length = 422

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 58/221 (26%), Positives = 89/221 (40%), Gaps = 31/221 (14%)

Query: 47  PEELLCFTERLEDLVCFWEEAASAGVG-PGNYSFSYQLEDEPW----KLCRLHQAPTARG 101
           P  + C+++ ++DL C W   A        NYS  Y+L    W      C  +       
Sbjct: 138 PVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLR---WYGQDNTCEEYHTVGPHS 194

Query: 102 AVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYHRV-IHINEVVLLDAPVGL-VARLAD 157
                C +P  D + F P E+ V A +  G+ R   + + I +VV  D P  + V+R+  
Sbjct: 195 -----CHIPK-DLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGG 248

Query: 158 ESGHVVLRWLPPPETP-----MTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRG 212
               + +RW+ PP            IRY V+ S        + V+ +  +T C L+ L+ 
Sbjct: 249 LEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSV-----DWKVVDDVSNQTSCRLAGLKP 303

Query: 213 RTRYTFAVRAR---MAEPSFGGFWSAWSEPVSLLTPSDLDP 250
            T Y   VR     +      G WS WS P +  TP    P
Sbjct: 304 GTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERP 344


>gi|28610151 interleukin 7 receptor precursor [Homo sapiens]
          Length = 459

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 7/103 (6%)

Query: 210 LRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPS------DLDPLILTLSLILVVIL 263
           L+    Y   VR+ + +  F GFWS WS      TP       ++DP++LT+S++    +
Sbjct: 195 LQPAAMYEIKVRS-IPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSV 253

Query: 264 VLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQL 306
            LL +LA +  ++ +K  +WP +P  +   E L    + N  +
Sbjct: 254 ALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNV 296


>gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo
           sapiens]
          Length = 259

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 54/213 (25%), Positives = 84/213 (39%), Gaps = 52/213 (24%)

Query: 200 EGRTECVLSNLRGRTRYTFAVRARMAEPSFGG--FWSAWSE----------PVSLLTPSD 247
           E      +  L     Y+F VR +  E  +G   + S WSE               TP+ 
Sbjct: 53  ENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTP 112

Query: 248 LDP------LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHK 301
             P      LI +L+++L+V L+LL++  L   R+ L     P +P P+S F GLF  H+
Sbjct: 113 PKPKLSKFILISSLAILLMVSLLLLSLWKLWRVRKFLI----PSVPDPKSIFPGLFEIHQ 168

Query: 302 GNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGS 361
           GNFQ W+                    A L          M   E G+  E PL+  +  
Sbjct: 169 GNFQEWITDTQNV--------------AHLH--------KMAGAEQGSGPEEPLVVQLAK 206

Query: 362 EHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDI 394
             A+   ++        +P +E+    GGS+ +
Sbjct: 207 TEAESPRML--------DPQTEEKEASGGSLQL 231


>gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo
           sapiens]
          Length = 371

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 22/127 (17%)

Query: 200 EGRTECVLSNLRGRTRYTFAVRARMAEPSFGG--FWSAWSE----------PVSLLTPSD 247
           E      +  L     Y+F VR +  E  +G   + S WSE               TP+ 
Sbjct: 165 ENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTP 224

Query: 248 LDP------LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHK 301
             P      LI +L+++L+V L+LL++  L      +K+ + P +P P+S F GLF  H+
Sbjct: 225 PKPKLSKFILISSLAILLMVSLLLLSLWKLWR----VKKFLIPSVPDPKSIFPGLFEIHQ 280

Query: 302 GNFQLWL 308
           GNFQ W+
Sbjct: 281 GNFQEWI 287


>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
           sapiens]
          Length = 420

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 9/169 (5%)

Query: 133 YHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDV-SAGNGAG 191
           + ++  ++ +  ++ P+ + A +  E   + ++W  P          YEV + +  NG  
Sbjct: 227 FDQLFALHAIDQINPPLNVTAEI--EGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYL 284

Query: 192 SVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSF-GGFWSAWSEPVSLLTPSDLDP 250
            ++++      T   +S +   ++Y   VRA ++      G WS WS+P+ +        
Sbjct: 285 QIEKL-----MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPL 339

Query: 251 LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTT 299
               + +I+  I  +L +L+L+     L  K++P IP+P+S  + LF T
Sbjct: 340 REWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVT 388


>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
           sapiens]
          Length = 420

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 9/169 (5%)

Query: 133 YHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDV-SAGNGAG 191
           + ++  ++ +  ++ P+ + A +  E   + ++W  P          YEV + +  NG  
Sbjct: 227 FDQLFALHAIDQINPPLNVTAEI--EGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYL 284

Query: 192 SVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSF-GGFWSAWSEPVSLLTPSDLDP 250
            ++++      T   +S +   ++Y   VRA ++      G WS WS+P+ +        
Sbjct: 285 QIEKL-----MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPL 339

Query: 251 LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTT 299
               + +I+  I  +L +L+L+     L  K++P IP+P+S  + LF T
Sbjct: 340 REWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVT 388


>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
          Length = 369

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 6/104 (5%)

Query: 207 LSNLRGRTRYTFAVRARMAEPSFGG--FWSAWSEPVSL-LTPSDLDPLILTLSLILVVIL 263
           L ++ G+ RYTF VR+R   P  G    WS WS P+      S  +P +  L  +++ + 
Sbjct: 210 LPSVDGQKRYTFRVRSRF-NPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVG 268

Query: 264 VLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLW 307
            +  +++LL     L ++  P IP+ ++  E L T + GNF  W
Sbjct: 269 SMGLIISLLCVYFWL-ERTMPRIPTLKN-LEDLVTEYHGNFSAW 310


>gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
          Length = 551

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 65/291 (22%), Positives = 108/291 (37%), Gaps = 32/291 (10%)

Query: 40  ALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEP----W-KLCRLH 94
           A  A  G  +  CF     ++ C W +  +          S Q+   P    W + C L 
Sbjct: 24  ASAAVNGTSQFTCFYNSRANISCVWSQDGAL------QDTSCQVHAWPDRRRWNQTCELL 77

Query: 95  QAPTARGAVRFWCSLPTADTSSFVPL-ELRVTAASGAPRYHRVIHIN-----EVVLLDAP 148
               A  A       P +   + V +  LRV    G     RV+ I      E + L AP
Sbjct: 78  PVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVR--WRVMAIQDFKPFENLRLMAP 135

Query: 149 VGLVARLADESGHVVLRW-LPPPETPMTSHIRYEV-DVSAGNGAGSVQRVEILEGRTECV 206
           + L   +  E+    + W +         H+ +E   +S G+       + + + +    
Sbjct: 136 ISLQV-VHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWIC 194

Query: 207 LSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD---------LDPLILTLSL 257
           L  L   T+Y F VR +  +  F   WS WS+P++  T            L  L++ LS 
Sbjct: 195 LETLTPDTQYEFQVRVKPLQGEFTT-WSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSG 253

Query: 258 ILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWL 308
               I+++  ++   +    LK+ +    P P   F  L + H G+ Q WL
Sbjct: 254 AFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWL 304


>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
           sapiens]
          Length = 1097

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/204 (25%), Positives = 84/204 (41%), Gaps = 15/204 (7%)

Query: 47  PEELLCFTERLEDLVCFWEEA-ASAGVGPGNYSFSYQLEDEPWKLCRLH--QAPTARGAV 103
           P++L C T  L++++C W     +A VGP   S++  +E    K  RL   +APT     
Sbjct: 336 PQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTL-VESFSGKYVRLKRAEAPTNESYQ 394

Query: 104 RFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVV 163
             +  LP  +  +F    L      G  +   +++I E V    P     +  + +  V 
Sbjct: 395 LLFQMLPNQEIYNFT---LNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTA-VK 450

Query: 164 LRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEI--LEGRTECV-LSNLRGRTRYTFAV 220
           L W  P      + +  E+++   N     + V I  +E  +  V L  L   T YTF  
Sbjct: 451 LSWHLPGNFAKINFL-CEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTF-- 507

Query: 221 RARMAEPSFGGFWSAWSEPVSLLT 244
           R R +  +F   WS WS     LT
Sbjct: 508 RIRCSTETFWK-WSKWSNKKQHLT 530



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 59/287 (20%), Positives = 122/287 (42%), Gaps = 54/287 (18%)

Query: 138 HINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVE 197
           +I E+  + AP   V   + +S  ++++W   P   +   +R  +    G G     ++ 
Sbjct: 718 YIEELAPIVAPNFTVEDTSADS--ILVKWEDIPVEELRGFLRGYL-FYFGKGERDTSKMR 774

Query: 198 ILE-GRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSE-------PVSLLTPSDLD 249
           +LE GR++  + N+   ++ T  +     + S+     A+++        + ++T  +  
Sbjct: 775 VLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSV 834

Query: 250 PLILTLSLILVVILVLLTVLALLSHRRA--LKQKIWPGIPSPESEFEGLFTTHKGNFQLW 307
            LI+ + + + V +++  V ++L +R+   +K+  +P IP+PE            N +  
Sbjct: 835 GLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPE------------NCKAL 882

Query: 308 LYQNDGC--------LWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLE-P 358
            +Q   C        L  +PCT      P ++EVL  R       +E  T+   P+ E P
Sbjct: 883 QFQKSVCEGSSALKTLEMNPCT------PNNVEVLETR--SAFPKIE-DTEIISPVAERP 933

Query: 359 VGSEHAQDTYLVLDKWLLPRNPP--SEDLPGP-----GGSVDIVAMD 398
                A+    V+  +     PP   E++P P     GG+  ++ +D
Sbjct: 934 EDRSDAEPENHVVVSYC----PPIIEEEIPNPAADEAGGTAQVIYID 976


>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
           sapiens]
          Length = 1097

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/204 (25%), Positives = 84/204 (41%), Gaps = 15/204 (7%)

Query: 47  PEELLCFTERLEDLVCFWEEA-ASAGVGPGNYSFSYQLEDEPWKLCRLH--QAPTARGAV 103
           P++L C T  L++++C W     +A VGP   S++  +E    K  RL   +APT     
Sbjct: 336 PQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTL-VESFSGKYVRLKRAEAPTNESYQ 394

Query: 104 RFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVV 163
             +  LP  +  +F    L      G  +   +++I E V    P     +  + +  V 
Sbjct: 395 LLFQMLPNQEIYNFT---LNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTA-VK 450

Query: 164 LRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEI--LEGRTECV-LSNLRGRTRYTFAV 220
           L W  P      + +  E+++   N     + V I  +E  +  V L  L   T YTF  
Sbjct: 451 LSWHLPGNFAKINFL-CEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTF-- 507

Query: 221 RARMAEPSFGGFWSAWSEPVSLLT 244
           R R +  +F   WS WS     LT
Sbjct: 508 RIRCSTETFWK-WSKWSNKKQHLT 530



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 59/287 (20%), Positives = 122/287 (42%), Gaps = 54/287 (18%)

Query: 138 HINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVE 197
           +I E+  + AP   V   + +S  ++++W   P   +   +R  +    G G     ++ 
Sbjct: 718 YIEELAPIVAPNFTVEDTSADS--ILVKWEDIPVEELRGFLRGYL-FYFGKGERDTSKMR 774

Query: 198 ILE-GRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSE-------PVSLLTPSDLD 249
           +LE GR++  + N+   ++ T  +     + S+     A+++        + ++T  +  
Sbjct: 775 VLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSV 834

Query: 250 PLILTLSLILVVILVLLTVLALLSHRRA--LKQKIWPGIPSPESEFEGLFTTHKGNFQLW 307
            LI+ + + + V +++  V ++L +R+   +K+  +P IP+PE            N +  
Sbjct: 835 GLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPE------------NCKAL 882

Query: 308 LYQNDGC--------LWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLE-P 358
            +Q   C        L  +PCT      P ++EVL  R       +E  T+   P+ E P
Sbjct: 883 QFQKSVCEGSSALKTLEMNPCT------PNNVEVLETR--SAFPKIE-DTEIISPVAERP 933

Query: 359 VGSEHAQDTYLVLDKWLLPRNPP--SEDLPGP-----GGSVDIVAMD 398
                A+    V+  +     PP   E++P P     GG+  ++ +D
Sbjct: 934 EDRSDAEPENHVVVSYC----PPIIEEEIPNPAADEAGGTAQVIYID 976


>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
          Length = 958

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 13/151 (8%)

Query: 109 LPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLL--DAPVGLVARLADESGHVVLRW 166
           +PTA  +  + + L++T+  G      ++ +  + ++  D P+GL   + D+ G++ + W
Sbjct: 200 VPTAKLNDTLLMCLKITSG-GVIFQSPLMSVQPINMVKPDPPLGLHMEITDD-GNLKISW 257

Query: 167 LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAE 226
             PP  P    ++Y+V  S  N    ++  + +   T  ++ ++   + Y   VR +  +
Sbjct: 258 SSPPLVPFP--LQYQVKYSE-NSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLD 314

Query: 227 PSFGGFWSAWSEPVSLLTPSDL---DPLILT 254
               G WS WS P  + T  D+    P ILT
Sbjct: 315 GP--GIWSDWSTP-RVFTTQDVIYFPPKILT 342


>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
          Length = 896

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 13/151 (8%)

Query: 109 LPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLL--DAPVGLVARLADESGHVVLRW 166
           +PTA  +  + + L++T+  G      ++ +  + ++  D P+GL   + D+ G++ + W
Sbjct: 200 VPTAKLNDTLLMCLKITSG-GVIFQSPLMSVQPINMVKPDPPLGLHMEITDD-GNLKISW 257

Query: 167 LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAE 226
             PP  P    ++Y+V  S  N    ++  + +   T  ++ ++   + Y   VR +  +
Sbjct: 258 SSPPLVPFP--LQYQVKYSE-NSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLD 314

Query: 227 PSFGGFWSAWSEPVSLLTPSDL---DPLILT 254
               G WS WS P  + T  D+    P ILT
Sbjct: 315 GP--GIWSDWSTP-RVFTTQDVIYFPPKILT 342


>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
          Length = 1165

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 13/151 (8%)

Query: 109 LPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLL--DAPVGLVARLADESGHVVLRW 166
           +PTA  +  + + L++T+  G      ++ +  + ++  D P+GL   + D+ G++ + W
Sbjct: 200 VPTAKLNDTLLMCLKITSG-GVIFQSPLMSVQPINMVKPDPPLGLHMEITDD-GNLKISW 257

Query: 167 LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAE 226
             PP  P    ++Y+V  S  N    ++  + +   T  ++ ++   + Y   VR +  +
Sbjct: 258 SSPPLVPFP--LQYQVKYSE-NSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLD 314

Query: 227 PSFGGFWSAWSEPVSLLTPSDL---DPLILT 254
               G WS WS P  + T  D+    P ILT
Sbjct: 315 GP--GIWSDWSTP-RVFTTQDVIYFPPKILT 342


>gi|21361766 zinc finger protein 692 isoform 2 [Homo sapiens]
          Length = 519

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 36/193 (18%)

Query: 266 LTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPC---TP 322
           L  L LLSH  + +  + PG+  P  +  GL         +W         W P    TP
Sbjct: 80  LQYLVLLSHAHSRECSLVPGLRGPGGQDGGL---------VWECSAGHTFSWGPSLSPTP 130

Query: 323 FTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPR--NP 380
                PASL   + R W +           G  L  + SEH + T     +  LPR   P
Sbjct: 131 SEAPKPASLPHTTRRSWCSEAT-------SGQELADLESEHDERT----QEARLPRRVGP 179

Query: 381 PSEDLPGPG---GSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLR 437
           P E  P PG   G  +    ++  E  S +S      SP+ +          D    L  
Sbjct: 180 PPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEP--------DAPRLLPS 231

Query: 438 PWTLCPELPPTPP 450
           P T  P+   TPP
Sbjct: 232 PVTCTPKEGETPP 244


>gi|209862873 zinc finger protein 692 isoform 1 [Homo sapiens]
          Length = 524

 Score = 38.9 bits (89), Expect = 0.011
 Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 36/193 (18%)

Query: 266 LTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPC---TP 322
           L  L LLSH  + +  + PG+  P  +  GL         +W         W P    TP
Sbjct: 85  LQYLVLLSHAHSRECSLVPGLRGPGGQDGGL---------VWECSAGHTFSWGPSLSPTP 135

Query: 323 FTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPR--NP 380
                PASL   + R W +           G  L  + SEH + T     +  LPR   P
Sbjct: 136 SEAPKPASLPHTTRRSWCSEAT-------SGQELADLESEHDERT----QEARLPRRVGP 184

Query: 381 PSEDLPGPG---GSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLR 437
           P E  P PG   G  +    ++  E  S +S      SP+ +          D    L  
Sbjct: 185 PPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEP--------DAPRLLPS 236

Query: 438 PWTLCPELPPTPP 450
           P T  P+   TPP
Sbjct: 237 PVTCTPKEGETPP 249


>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
           sapiens]
          Length = 427

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 64/291 (21%), Positives = 116/291 (39%), Gaps = 44/291 (15%)

Query: 49  ELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPW--KLCRLHQAPTA-RGAVRF 105
           EL C    L  + C W    +      NY+  Y      W   L ++HQ     R    F
Sbjct: 131 ELQCIWHNLSYMKCSWLPGRNTSPDT-NYTLYY------WHRSLEKIHQCENIFREGQYF 183

Query: 106 WCS--LPTADTSSFVPLELRVTAASGAPRYH---RVIHINEVVLLDAPVGLVARLADESG 160
            CS  L     SSF    +++     A +      ++ +   V  D P   +  L+  + 
Sbjct: 184 GCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPH--IKNLSFHND 241

Query: 161 HVVLRWLPPPETPMTSHIRYEVDVSAG----NGAGSVQRVEI--------LEGRTECVLS 208
            + ++W   P+  ++  + YEV+V+      +    VQ  +         +E  +  ++ 
Sbjct: 242 DLYVQW-ENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVP 300

Query: 209 NLRGRTRYTFAVRARMAEPSFGG--FWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLL 266
            +   T  T  +R +  +  +     WS WS+ +S+    +   L +T+ L++V ++V  
Sbjct: 301 GVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRN-STLYITM-LLIVPVIVAG 358

Query: 267 TVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWW 317
            ++ LL + + LK  I+P IP P   F+ +F            QND  L W
Sbjct: 359 AIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGD----------QNDDTLHW 399


>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
           [Homo sapiens]
          Length = 918

 Score = 37.4 bits (85), Expect = 0.032
 Identities = 37/171 (21%), Positives = 66/171 (38%), Gaps = 23/171 (13%)

Query: 191 GSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDP 250
           G+   V +    TE  LS+L   T Y   + A   E    G    ++ P       +++ 
Sbjct: 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK--FAQGEIEA 620

Query: 251 LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQ 310
           +++ + L  + +  LL VL   + R  +K+ IWP +P P                     
Sbjct: 621 IVVPVCLAFL-LTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSH----------------- 662

Query: 311 NDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGS 361
                 WSP TP   +  +  ++ S+  +  +  VE   +D+ P  E + S
Sbjct: 663 ---IAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKS 710



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 202 RTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD 247
           R+   + +L+  T Y F +R    +    G+WS WSE  S +T  D
Sbjct: 281 RSSFTVQDLKPFTEYVFRIRCMKEDGK--GYWSDWSEEASGITYED 324


>gi|5031785 interleukin 12 receptor, beta 1 isoform 1 precursor
           [Homo sapiens]
          Length = 662

 Score = 36.2 bits (82), Expect = 0.072
 Identities = 49/173 (28%), Positives = 68/173 (39%), Gaps = 25/173 (14%)

Query: 203 TECVLSNLRGRTRYTFAVRARMAEPSFGGFW--SAWSEPVSLLTPSDL-DPLILTLSLIL 259
           T+  LS LR    YT  VRA  A       W    WS+P        + D LI   SL  
Sbjct: 503 TQVTLSGLRAGVAYTVQVRADTA-------WLRGVWSQPQRFSIEVQVSDWLIFFASLGS 555

Query: 260 VVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSP 319
            + ++L+ VL  L   RA +  + P +P+P +     F   K  +Q          W +P
Sbjct: 556 FLSILLVGVLGYLGLNRAARH-LCPPLPTPCASSAIEFPGGKETWQ----------WINP 604

Query: 320 CTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLD 372
              F E+      ++ E  W   +  EP    E P   P   E A DT L L+
Sbjct: 605 -VDFQEEASLQEALVVEMSWDKGERTEPLEKTELPEGAP---ELALDTELSLE 653


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 7/93 (7%)

Query: 386 PGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLRPWTLCPEL 445
           PGP G         G + S  S  L   P P+G +      ++L P    L    +C + 
Sbjct: 512 PGPSGP-------PGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDC 564

Query: 446 PPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQG 478
           PP PP L  L     D G+        ++G +G
Sbjct: 565 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 597


>gi|149944516 tet oncogene family member 3 [Homo sapiens]
          Length = 1660

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 45/173 (26%), Positives = 63/173 (36%), Gaps = 39/173 (22%)

Query: 374 WLLPRNPPSEDLPGPGGSV------DIVAMDEGSEASSCSSALASK-------------- 413
           W + + P  E  PGP  +       D+VA    +EA S   AL+++              
Sbjct: 39  WRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFNREMSREAG 98

Query: 414 -------PSPEGASAASFEYTILDPSSQLLRPWTLCPEL----PPTPPHLKYL----YLV 458
                  P PEG SA S +   L  +  L R     P      P  P +L++L      V
Sbjct: 99  NNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSV 158

Query: 459 VSDSGISTDYSSGDSQGAQGGLSDGPYSNPYENSLIPAAEP---LPPSYVACS 508
           V + G       G     + GL   P + P  +S +P   P   LP S  A S
Sbjct: 159 VMEGGEERPRLPGPLPPGEAGL-PAPSTRPLLSSEVPQISPQEGLPLSQSALS 210


>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
          Length = 764

 Score = 34.7 bits (78), Expect = 0.21
 Identities = 50/235 (21%), Positives = 82/235 (34%), Gaps = 18/235 (7%)

Query: 10  PQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAAS 69
           P   +L ++   A W  P      KF S AAL A   PE + C     ++L C W     
Sbjct: 26  PSCVNLGMMWTWALWMLPSLC---KF-SLAALPAK--PENISCVYYYRKNLTCTWSPGKE 79

Query: 70  AGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASG 129
                     +Y   ++             R +  F+  LP         +E+      G
Sbjct: 80  TSYTQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFF--LPRITIPDNYTIEVEAENGDG 137

Query: 130 APRYHRVIHINEVVLLDAPVGL--VARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAG 187
             + H      E +    P  +  V  +      + + W+ P   P++S ++Y +     
Sbjct: 138 VIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTV 197

Query: 188 NGAGSVQRVEILEGRTE----CVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSE 238
           N   S   V   + R +      L+ L+  T Y  A+R  + E     FWS WS+
Sbjct: 198 NST-SWMEVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESK---FWSDWSQ 248



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 12/147 (8%)

Query: 162 VVLRWLPPPETPMTSHI-RYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAV 220
           V + W   P++     I  Y +   A  G G  + V       +  L +L+ +T Y   V
Sbjct: 469 VTITWKEIPKSERKGIICNYTIFYQAEGGKGFSKTVN--SSILQYGLESLKRKTSYIVQV 526

Query: 221 RARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLIL--VVILVLLTVLALLSHRRAL 278
              MA  S GG  +  S     L+ S  + +++T SLI   ++IL++LTV   L     L
Sbjct: 527 ---MASTSAGGT-NGTSINFKTLSFSVFEIILIT-SLIGGGLLILIILTVAYGLKKPNKL 581

Query: 279 KQKIWPGIPSPESEFEGLFTTHKGNFQ 305
               WP +P+P      + T H  +F+
Sbjct: 582 THLCWPTVPNPAE--SSIATWHGDDFK 606


>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
          Length = 976

 Score = 34.3 bits (77), Expect = 0.28
 Identities = 44/168 (26%), Positives = 56/168 (33%), Gaps = 32/168 (19%)

Query: 66  EAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVT 125
           E A     PG   F ++  + P   C  H  P+  GA    C           P  +  T
Sbjct: 270 EDACQACSPG--FFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQD-PASMPCT 326

Query: 126 AASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDV- 184
               AP Y               VG+ A+       V LRW PP ++     I Y V   
Sbjct: 327 RPPSAPHYLTA------------VGMGAK-------VELRWTPPQDSGGREDIVYSVTCE 367

Query: 185 -------SAGNGAGSVQRVEILEG--RTECVLSNLRGRTRYTFAVRAR 223
                    G    SV+  E   G  RT   +S+L     YTF V AR
Sbjct: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEAR 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,919,733
Number of Sequences: 37866
Number of extensions: 1327640
Number of successful extensions: 4411
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 78
Number of HSP's that attempted gapping in prelim test: 4339
Number of HSP's gapped (non-prelim): 147
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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