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Search of human proteins with 4503591
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503591 erythropoietin receptor precursor [Homo sapiens]
(508 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503591 erythropoietin receptor precursor [Homo sapiens] 1050 0.0
gi|29171682 interleukin 9 receptor precursor [Homo sapiens] 74 2e-13
gi|4885491 myeloproliferative leukemia virus oncogene precursor ... 61 2e-09
gi|31083174 interleukin 21 receptor precursor [Homo sapiens] 57 4e-08
gi|11141869 interleukin 21 receptor precursor [Homo sapiens] 57 4e-08
gi|31083180 interleukin 21 receptor precursor [Homo sapiens] 57 4e-08
gi|4506107 prolactin receptor [Homo sapiens] 56 7e-08
gi|4559408 colony stimulating factor 2 receptor, beta precursor ... 55 2e-07
gi|4758062 cytokine receptor-like factor 1 [Homo sapiens] 54 3e-07
gi|28610151 interleukin 7 receptor precursor [Homo sapiens] 54 4e-07
gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo sapi... 52 2e-06
gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo sapi... 51 2e-06
gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [H... 47 3e-05
gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [H... 47 3e-05
gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens] 44 3e-04
gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens] 41 0.003
gi|4504993 leukemia inhibitory factor receptor precursor [Homo s... 41 0.003
gi|189083786 leukemia inhibitory factor receptor precursor [Homo... 41 0.003
gi|51093381 leptin receptor isoform 3 [Homo sapiens] 40 0.007
gi|51093379 leptin receptor isoform 2 [Homo sapiens] 40 0.007
gi|40254464 leptin receptor isoform 1 [Homo sapiens] 40 0.007
gi|21361766 zinc finger protein 692 isoform 2 [Homo sapiens] 39 0.011
gi|209862873 zinc finger protein 692 isoform 1 [Homo sapiens] 39 0.011
gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo sapi... 39 0.015
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ... 37 0.032
gi|5031785 interleukin 12 receptor, beta 1 isoform 1 precursor [... 36 0.072
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 35 0.12
gi|149944516 tet oncogene family member 3 [Homo sapiens] 35 0.21
gi|115430248 gp130-like monocyte receptor [Homo sapiens] 35 0.21
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 34 0.28
>gi|4503591 erythropoietin receptor precursor [Homo sapiens]
Length = 508
Score = 1050 bits (2715), Expect = 0.0
Identities = 508/508 (100%), Positives = 508/508 (100%)
Query: 1 MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL 60
MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL
Sbjct: 1 MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL 60
Query: 61 VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL 120
VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL
Sbjct: 61 VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL 120
Query: 121 ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY 180
ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY
Sbjct: 121 ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY 180
Query: 181 EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV 240
EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV
Sbjct: 181 EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV 240
Query: 241 SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH 300
SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH
Sbjct: 241 SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH 300
Query: 301 KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG 360
KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG
Sbjct: 301 KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG 360
Query: 361 SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS 420
SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS
Sbjct: 361 SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS 420
Query: 421 AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL 480
AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL
Sbjct: 421 AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL 480
Query: 481 SDGPYSNPYENSLIPAAEPLPPSYVACS 508
SDGPYSNPYENSLIPAAEPLPPSYVACS
Sbjct: 481 SDGPYSNPYENSLIPAAEPLPPSYVACS 508
>gi|29171682 interleukin 9 receptor precursor [Homo sapiens]
Length = 521
Score = 74.3 bits (181), Expect = 2e-13
Identities = 106/416 (25%), Positives = 156/416 (37%), Gaps = 92/416 (22%)
Query: 52 CFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPT 111
C T + + C W A G G PW L +QAP C L
Sbjct: 56 CLTNNILRIDCHWS-APELGQG-----------SSPWLLFTSNQAPGGTHK----CILRG 99
Query: 112 ADTSSFVPLE-LRVTAASGAPRYHRVIHINEVVLL-------------DAPVGLVARLAD 157
++ + +P E + V + + +H + E V L D P L + ++
Sbjct: 100 SECTVVLPPEAVLVPSDNFTITFHHCMSGREQVSLVDPEYLPRRHVKLDPPSDLQSNIS- 158
Query: 158 ESGHVVLRW-LPPPETPMTSHIRYEVDVSAGNGAGS-VQRVEILEGRTECVLSNLRGRTR 215
SGH +L W + P PMT+ + YE+ A Q + + G T +L
Sbjct: 159 -SGHCILTWSISPALEPMTTLLSYELAFKKQEEAWEQAQHRDHIVGVTWLILEAFELDPG 217
Query: 216 YTFAVRARMA----------EPSFGGFWSAWSEPVSLLTPSDLDPLILTL-----SLILV 260
+ R R+ E + G WS WS+PV P PLI +L+ V
Sbjct: 218 FIHEARLRVQMATLEDDVVEEERYTGQWSEWSQPVCFQAPQRQGPLIPPWGWPGNTLVAV 277
Query: 261 VILVLLT----VLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWL-YQNDGCL 315
I +LLT +L LS R +K+ + +PSP F+ L++ H GNFQ W+ G L
Sbjct: 278 SIFLLLTGPTYLLFKLSPR--VKRIFYQNVPSPAMFFQPLYSVHNGNFQTWMGAHGAGVL 335
Query: 316 WWSPCT--------PFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQD- 366
C P ++ A L R W ++ E + EGP G+ ++D
Sbjct: 336 LSQDCAGTPQGALEPCVQEATALLTCGPARPWKSVALEE---EQEGPGTRLPGNLSSEDV 392
Query: 367 -------------TYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSA 409
YL + W P S P P S EGS +SS SS+
Sbjct: 393 LPAGCTEWRVQTLAYLPQEDWA----PTSLTRPAPPDS-------EGSRSSSSSSS 437
>gi|4885491 myeloproliferative leukemia virus oncogene precursor
[Homo sapiens]
Length = 635
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/283 (23%), Positives = 99/283 (34%), Gaps = 62/283 (21%)
Query: 16 CLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPG 75
CLLLA P NL + S+ L A E L CF+ EDL CFW+E +A G
Sbjct: 12 CLLLA------PQNLA--QVSSQDVSLLASDSEPLKCFSRTFEDLTCFWDEEEAA--PSG 61
Query: 76 NYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLP-TADTSSFVPLELRV-TAASGAPRY 133
Y Y E + C L R+ C P + F PL L V R
Sbjct: 62 TYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFPLHLWVKNVFLNQTRT 121
Query: 134 HRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSV 193
RV+ ++ V L P + A + G + + W P ++ +RYE+ + S
Sbjct: 122 QRVLFVDSVGLPAPPSIIKAMGGSQPGELQISW-EEPAPEISDFLRYELRYGPRDPKNST 180
Query: 194 --QRVEILEGRTEC---------------------------------------------- 205
++++ T C
Sbjct: 181 GPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDGPKQTSPSREASALTAEGGS 240
Query: 206 -VLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD 247
++S L+ Y +R+ S GG W +WS PV++ P D
Sbjct: 241 CLISGLQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTVDLPGD 283
Score = 60.5 bits (145), Expect = 4e-09
Identities = 67/254 (26%), Positives = 111/254 (43%), Gaps = 25/254 (9%)
Query: 50 LLCFTERLEDLVCFWEE---AASAGVGPGNYSFSYQLEDEP-WKLCRLHQA--PTARGAV 103
L CFT L+++ C W++ A+S G + + + P W+ C + P +
Sbjct: 289 LQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCPRDRYPIWENCEEEEKTNPGLQTPQ 348
Query: 104 RFWCSLPTADTSSFVPLELRVTAASGAPRYH--RVIHINEVVLLDAPVGLVARLADESGH 161
C + + S + + + VT A G + I++ V L P ++ SGH
Sbjct: 349 FSRCHFKSRN-DSIIHILVEVTTAPGTVHSYLGSPFWIHQAVRLPTPNLHWREIS--SGH 405
Query: 162 VVLRWLPPPETPMTS---HIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTF 218
+ L W P +RY G G + +E G L LR R+RY
Sbjct: 406 LELEWQHPSSWAAQETCYQLRY-----TGEGHQDWKVLEPPLGARGGTLE-LRPRSRYRL 459
Query: 219 AVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL-----S 273
+RAR+ P++ G WS+WS+P + T ++ + L +L LV+ L + L LL +
Sbjct: 460 QLRARLNGPTYQGPWSSWSDPTRVETATETAWISLVTALHLVLGLSAVLGLLLLRWQFPA 519
Query: 274 HRRALKQKIWPGIP 287
H R L+ +WP +P
Sbjct: 520 HYRRLRHALWPSLP 533
>gi|31083174 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 57.0 bits (136), Expect = 4e-08
Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)
Query: 46 GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101
G +L+C+T+ L+ ++C E + P + ++Q + E K C LH++
Sbjct: 19 GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75
Query: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
+ C + + + +T SG + + AP V SG
Sbjct: 76 HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133
Query: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213
+ W E P + ++YE+ +V +++ ++ R+ +L R
Sbjct: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193
Query: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272
+ Y VRA M S+ G WS WS+PV T S+ L+L+++LV++ + A
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321
S + L +KIW +PSPE F L+ G+F+ W+ +P T
Sbjct: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304
Query: 322 PFTEDPPASLEVLS 335
P++ + P++LEV S
Sbjct: 305 PWSPEVPSTLEVYS 318
>gi|11141869 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 57.0 bits (136), Expect = 4e-08
Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)
Query: 46 GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101
G +L+C+T+ L+ ++C E + P + ++Q + E K C LH++
Sbjct: 19 GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75
Query: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
+ C + + + +T SG + + AP V SG
Sbjct: 76 HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133
Query: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213
+ W E P + ++YE+ +V +++ ++ R+ +L R
Sbjct: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193
Query: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272
+ Y VRA M S+ G WS WS+PV T S+ L+L+++LV++ + A
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321
S + L +KIW +PSPE F L+ G+F+ W+ +P T
Sbjct: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304
Query: 322 PFTEDPPASLEVLS 335
P++ + P++LEV S
Sbjct: 305 PWSPEVPSTLEVYS 318
>gi|31083180 interleukin 21 receptor precursor [Homo sapiens]
Length = 538
Score = 57.0 bits (136), Expect = 4e-08
Identities = 74/314 (23%), Positives = 132/314 (42%), Gaps = 38/314 (12%)
Query: 46 GPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWK----LCRLHQAPTARG 101
G +L+C+T+ L+ ++C E + P + ++Q + E K C LH++
Sbjct: 19 GCPDLVCYTDYLQTVICILE---MWNLHPSTLTLTWQDQYEELKDEATSCSLHRSAHNAT 75
Query: 102 AVRFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
+ C + + + +T SG + + AP V SG
Sbjct: 76 HATYTCHMDVFHFMADDIFSVNITDQSGNYSQECGSFLLAESIKPAPPFNVT--VTFSGQ 133
Query: 162 VVLRWLPPPETP----MTSHIRYEVDVSAGNGAGSV---QRVEILEGRTECVLS-NLRGR 213
+ W E P + ++YE+ +V +++ ++ R+ +L R
Sbjct: 134 YNISWRSDYEDPAFYMLKGKLQYELQYRNRGDPWAVSPRRKLISVDSRSVSLLPLEFRKD 193
Query: 214 TRYTFAVRAR-MAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALL 272
+ Y VRA M S+ G WS WS+PV T S+ L+L+++LV++ + A
Sbjct: 194 SSYELQVRAGPMPGSSYQGTWSEWSDPVIFQTQSEELKEGWNPHLLLLLLLVIVFIPAFW 253
Query: 273 SHRR----ALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCT------- 321
S + L +KIW +PSPE F L+ G+F+ W+ +P T
Sbjct: 254 SLKTHPLWRLWKKIW-AVPSPERFFMPLYKGCSGDFKKWV--------GAPFTGSSLELG 304
Query: 322 PFTEDPPASLEVLS 335
P++ + P++LEV S
Sbjct: 305 PWSPEVPSTLEVYS 318
>gi|4506107 prolactin receptor [Homo sapiens]
Length = 622
Score = 56.2 bits (134), Expect = 7e-08
Identities = 65/299 (21%), Positives = 114/299 (38%), Gaps = 24/299 (8%)
Query: 47 PEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFW 106
PE C + E C+W G+ P NYS +Y E E +H+ P
Sbjct: 31 PEIFKCRSPNKETFTCWWRPGTDGGL-PTNYSLTYHREGETL----MHECPDYITGGPNS 85
Query: 107 CSLPTADTSSFVPLELRVTAAS---GAPRYHRVIHINEVVLLDAPVGLVARLA---DESG 160
C TS + + V A + + + + +V D P+ L + D
Sbjct: 86 CHFGKQYTSMWRTYIMMVNATNQMGSSFSDELYVDVTYIVQPDPPLELAVEVKQPEDRKP 145
Query: 161 HVVLRWLPPPETPMTSH---IRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYT 217
++ ++W PP + + + YE+ + A + +TE + +L +Y
Sbjct: 146 YLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAE--WEIHFAGQQTEFKILSLHPGQKYL 203
Query: 218 FAVRARMAEPSFGGFWSAWSEPVSLLTPSDL---DPLILTLSLILVVILVLLTVLALLSH 274
VR + G+WSAWS + PSD D + +L ++ L+ V A+
Sbjct: 204 VQVRCKPDH----GYWSAWSPATFIQIPSDFTMNDTTVWISVAVLSAVICLIIVWAVALK 259
Query: 275 RRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEV 333
++ I+P +P P+ + KG + L GC + P + + + LEV
Sbjct: 260 GYSMVTCIFPPVPGPKIKGFDAHLLEKGKSE-ELLSALGCQDFPPTSDYEDLLVEYLEV 317
>gi|4559408 colony stimulating factor 2 receptor, beta precursor
[Homo sapiens]
Length = 897
Score = 55.1 bits (131), Expect = 2e-07
Identities = 100/433 (23%), Positives = 150/433 (34%), Gaps = 68/433 (15%)
Query: 47 PEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAV--- 103
P+ L CF + L C WE F D + C +P R +
Sbjct: 245 PQNLECFFDGAAVLSCSWEVRKEVASSVSFGLFYKPSPDAGEEEC----SPVLREGLGSL 300
Query: 104 --RFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGH 161
R C +P D ++ + V ++I AP L + +
Sbjct: 301 HTRHHCQIPVPDPATHGQYIVSVQPRRAEKHIKSSVNIQM-----APPSL--NVTKDGDS 353
Query: 162 VVLRW----LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYT 217
LRW + T I+Y D + + + E L+ L L TRY
Sbjct: 354 YSLRWETMKMRYEHIDHTFEIQYRKDTATWKDS----KTETLQNAHSMALPALEPSTRYW 409
Query: 218 FAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRA 277
VR R + + G WS WSE S T S L +L L +I + I VLL + +
Sbjct: 410 ARVRVRTSRTGYNGIWSEWSEARSWDTESVLPMWVLALIVIFLTIAVLLALRFCGIYGYR 469
Query: 278 LKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSP--CTPFTEDPPASLEVLS 335
L++K IP+P L+QN W P + FT P
Sbjct: 470 LRRKWEEKIPNPSKSH--------------LFQNGSAELWPPGSMSAFTSGSPP-----H 510
Query: 336 ERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIV 395
+ WG+ G + PVG ++ + L ++ +PPS GP +
Sbjct: 511 QGPWGSRFPELEG-------VFPVGFGDSEVSPLTIEDPKHVCDPPS----GPDTTPAAS 559
Query: 396 AMDEGSEASSCSSALASKPSPEGASAASFEYT---ILDPSSQLLRPWTLCPELP------ 446
+ S A+ +PE A+SF++ + P S+ L PE P
Sbjct: 560 DLPTEQPPSPQPGPPAASHTPE-KQASSFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQ 618
Query: 447 --PTPPHLKYLYL 457
P P L+YL L
Sbjct: 619 KSPPPGSLEYLCL 631
>gi|4758062 cytokine receptor-like factor 1 [Homo sapiens]
Length = 422
Score = 54.3 bits (129), Expect = 3e-07
Identities = 58/221 (26%), Positives = 89/221 (40%), Gaps = 31/221 (14%)
Query: 47 PEELLCFTERLEDLVCFWEEAASAGVG-PGNYSFSYQLEDEPW----KLCRLHQAPTARG 101
P + C+++ ++DL C W A NYS Y+L W C +
Sbjct: 138 PVNISCWSKNMKDLTCRWTPGAHGETFLHTNYSLKYKLR---WYGQDNTCEEYHTVGPHS 194
Query: 102 AVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYHRV-IHINEVVLLDAPVGL-VARLAD 157
C +P D + F P E+ V A + G+ R + + I +VV D P + V+R+
Sbjct: 195 -----CHIPK-DLALFTPYEIWVEATNRLGSARSDVLTLDILDVVTTDPPPDVHVSRVGG 248
Query: 158 ESGHVVLRWLPPPETP-----MTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRG 212
+ +RW+ PP IRY V+ S + V+ + +T C L+ L+
Sbjct: 249 LEDQLSVRWVSPPALKDFLFQAKYQIRYRVEDSV-----DWKVVDDVSNQTSCRLAGLKP 303
Query: 213 RTRYTFAVRAR---MAEPSFGGFWSAWSEPVSLLTPSDLDP 250
T Y VR + G WS WS P + TP P
Sbjct: 304 GTVYFVQVRCNPFGIYGSKKAGIWSEWSHPTAASTPRSERP 344
>gi|28610151 interleukin 7 receptor precursor [Homo sapiens]
Length = 459
Score = 53.5 bits (127), Expect = 4e-07
Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 7/103 (6%)
Query: 210 LRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPS------DLDPLILTLSLILVVIL 263
L+ Y VR+ + + F GFWS WS TP ++DP++LT+S++ +
Sbjct: 195 LQPAAMYEIKVRS-IPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSV 253
Query: 264 VLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQL 306
LL +LA + ++ +K +WP +P + E L + N +
Sbjct: 254 ALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNV 296
>gi|59958359 cytokine receptor-like factor 2 isoform 2 [Homo
sapiens]
Length = 259
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/213 (25%), Positives = 84/213 (39%), Gaps = 52/213 (24%)
Query: 200 EGRTECVLSNLRGRTRYTFAVRARMAEPSFGG--FWSAWSE----------PVSLLTPSD 247
E + L Y+F VR + E +G + S WSE TP+
Sbjct: 53 ENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTP 112
Query: 248 LDP------LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHK 301
P LI +L+++L+V L+LL++ L R+ L P +P P+S F GLF H+
Sbjct: 113 PKPKLSKFILISSLAILLMVSLLLLSLWKLWRVRKFLI----PSVPDPKSIFPGLFEIHQ 168
Query: 302 GNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGS 361
GNFQ W+ A L M E G+ E PL+ +
Sbjct: 169 GNFQEWITDTQNV--------------AHLH--------KMAGAEQGSGPEEPLVVQLAK 206
Query: 362 EHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDI 394
A+ ++ +P +E+ GGS+ +
Sbjct: 207 TEAESPRML--------DPQTEEKEASGGSLQL 231
>gi|19923096 cytokine receptor-like factor 2 isoform 1 [Homo
sapiens]
Length = 371
Score = 51.2 bits (121), Expect = 2e-06
Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 22/127 (17%)
Query: 200 EGRTECVLSNLRGRTRYTFAVRARMAEPSFGG--FWSAWSE----------PVSLLTPSD 247
E + L Y+F VR + E +G + S WSE TP+
Sbjct: 165 ENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTP 224
Query: 248 LDP------LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHK 301
P LI +L+++L+V L+LL++ L +K+ + P +P P+S F GLF H+
Sbjct: 225 PKPKLSKFILISSLAILLMVSLLLLSLWKLWR----VKKFLIPSVPDPKSIFPGLFEIHQ 280
Query: 302 GNFQLWL 308
GNFQ W+
Sbjct: 281 GNFQEWI 287
>gi|28559021 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 47.4 bits (111), Expect = 3e-05
Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Query: 133 YHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDV-SAGNGAG 191
+ ++ ++ + ++ P+ + A + E + ++W P YEV + + NG
Sbjct: 227 FDQLFALHAIDQINPPLNVTAEI--EGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYL 284
Query: 192 SVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSF-GGFWSAWSEPVSLLTPSDLDP 250
++++ T +S + ++Y VRA ++ G WS WS+P+ +
Sbjct: 285 QIEKL-----MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPL 339
Query: 251 LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTT 299
+ +I+ I +L +L+L+ L K++P IP+P+S + LF T
Sbjct: 340 REWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVT 388
>gi|28559027 interleukin 5 receptor, alpha isoform 1 precursor [Homo
sapiens]
Length = 420
Score = 47.4 bits (111), Expect = 3e-05
Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 9/169 (5%)
Query: 133 YHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDV-SAGNGAG 191
+ ++ ++ + ++ P+ + A + E + ++W P YEV + + NG
Sbjct: 227 FDQLFALHAIDQINPPLNVTAEI--EGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYL 284
Query: 192 SVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSF-GGFWSAWSEPVSLLTPSDLDP 250
++++ T +S + ++Y VRA ++ G WS WS+P+ +
Sbjct: 285 QIEKL-----MTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPL 339
Query: 251 LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTT 299
+ +I+ I +L +L+L+ L K++P IP+P+S + LF T
Sbjct: 340 REWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVT 388
>gi|4557882 interleukin 2 receptor, gamma precursor [Homo sapiens]
Length = 369
Score = 43.9 bits (102), Expect = 3e-04
Identities = 32/104 (30%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
Query: 207 LSNLRGRTRYTFAVRARMAEPSFGG--FWSAWSEPVSL-LTPSDLDPLILTLSLILVVIL 263
L ++ G+ RYTF VR+R P G WS WS P+ S +P + L +++ +
Sbjct: 210 LPSVDGQKRYTFRVRSRF-NPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVG 268
Query: 264 VLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLW 307
+ +++LL L ++ P IP+ ++ E L T + GNF W
Sbjct: 269 SMGLIISLLCVYFWL-ERTMPRIPTLKN-LEDLVTEYHGNFSAW 310
>gi|4504665 interleukin 2 receptor beta precursor [Homo sapiens]
Length = 551
Score = 40.8 bits (94), Expect = 0.003
Identities = 65/291 (22%), Positives = 108/291 (37%), Gaps = 32/291 (10%)
Query: 40 ALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEP----W-KLCRLH 94
A A G + CF ++ C W + + S Q+ P W + C L
Sbjct: 24 ASAAVNGTSQFTCFYNSRANISCVWSQDGAL------QDTSCQVHAWPDRRRWNQTCELL 77
Query: 95 QAPTARGAVRFWCSLPTADTSSFVPL-ELRVTAASGAPRYHRVIHIN-----EVVLLDAP 148
A A P + + V + LRV G RV+ I E + L AP
Sbjct: 78 PVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVR--WRVMAIQDFKPFENLRLMAP 135
Query: 149 VGLVARLADESGHVVLRW-LPPPETPMTSHIRYEV-DVSAGNGAGSVQRVEILEGRTECV 206
+ L + E+ + W + H+ +E +S G+ + + + +
Sbjct: 136 ISLQV-VHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWIC 194
Query: 207 LSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD---------LDPLILTLSL 257
L L T+Y F VR + + F WS WS+P++ T L L++ LS
Sbjct: 195 LETLTPDTQYEFQVRVKPLQGEFTT-WSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSG 253
Query: 258 ILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWL 308
I+++ ++ + LK+ + P P F L + H G+ Q WL
Sbjct: 254 AFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWL 304
>gi|4504993 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/204 (25%), Positives = 84/204 (41%), Gaps = 15/204 (7%)
Query: 47 PEELLCFTERLEDLVCFWEEA-ASAGVGPGNYSFSYQLEDEPWKLCRLH--QAPTARGAV 103
P++L C T L++++C W +A VGP S++ +E K RL +APT
Sbjct: 336 PQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTL-VESFSGKYVRLKRAEAPTNESYQ 394
Query: 104 RFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVV 163
+ LP + +F L G + +++I E V P + + + V
Sbjct: 395 LLFQMLPNQEIYNFT---LNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTA-VK 450
Query: 164 LRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEI--LEGRTECV-LSNLRGRTRYTFAV 220
L W P + + E+++ N + V I +E + V L L T YTF
Sbjct: 451 LSWHLPGNFAKINFL-CEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTF-- 507
Query: 221 RARMAEPSFGGFWSAWSEPVSLLT 244
R R + +F WS WS LT
Sbjct: 508 RIRCSTETFWK-WSKWSNKKQHLT 530
Score = 35.4 bits (80), Expect = 0.12
Identities = 59/287 (20%), Positives = 122/287 (42%), Gaps = 54/287 (18%)
Query: 138 HINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVE 197
+I E+ + AP V + +S ++++W P + +R + G G ++
Sbjct: 718 YIEELAPIVAPNFTVEDTSADS--ILVKWEDIPVEELRGFLRGYL-FYFGKGERDTSKMR 774
Query: 198 ILE-GRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSE-------PVSLLTPSDLD 249
+LE GR++ + N+ ++ T + + S+ A+++ + ++T +
Sbjct: 775 VLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSV 834
Query: 250 PLILTLSLILVVILVLLTVLALLSHRRA--LKQKIWPGIPSPESEFEGLFTTHKGNFQLW 307
LI+ + + + V +++ V ++L +R+ +K+ +P IP+PE N +
Sbjct: 835 GLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPE------------NCKAL 882
Query: 308 LYQNDGC--------LWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLE-P 358
+Q C L +PCT P ++EVL R +E T+ P+ E P
Sbjct: 883 QFQKSVCEGSSALKTLEMNPCT------PNNVEVLETR--SAFPKIE-DTEIISPVAERP 933
Query: 359 VGSEHAQDTYLVLDKWLLPRNPP--SEDLPGP-----GGSVDIVAMD 398
A+ V+ + PP E++P P GG+ ++ +D
Sbjct: 934 EDRSDAEPENHVVVSYC----PPIIEEEIPNPAADEAGGTAQVIYID 976
>gi|189083786 leukemia inhibitory factor receptor precursor [Homo
sapiens]
Length = 1097
Score = 40.8 bits (94), Expect = 0.003
Identities = 53/204 (25%), Positives = 84/204 (41%), Gaps = 15/204 (7%)
Query: 47 PEELLCFTERLEDLVCFWEEA-ASAGVGPGNYSFSYQLEDEPWKLCRLH--QAPTARGAV 103
P++L C T L++++C W +A VGP S++ +E K RL +APT
Sbjct: 336 PQQLNCETHDLKEIICSWNPGRVTALVGPRATSYTL-VESFSGKYVRLKRAEAPTNESYQ 394
Query: 104 RFWCSLPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVV 163
+ LP + +F L G + +++I E V P + + + V
Sbjct: 395 LLFQMLPNQEIYNFT---LNAHNPLGRSQSTILVNITEKVYPHTPTSFKVKDINSTA-VK 450
Query: 164 LRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEI--LEGRTECV-LSNLRGRTRYTFAV 220
L W P + + E+++ N + V I +E + V L L T YTF
Sbjct: 451 LSWHLPGNFAKINFL-CEIEIKKSNSVQEQRNVTIKGVENSSYLVALDKLNPYTLYTF-- 507
Query: 221 RARMAEPSFGGFWSAWSEPVSLLT 244
R R + +F WS WS LT
Sbjct: 508 RIRCSTETFWK-WSKWSNKKQHLT 530
Score = 35.4 bits (80), Expect = 0.12
Identities = 59/287 (20%), Positives = 122/287 (42%), Gaps = 54/287 (18%)
Query: 138 HINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVE 197
+I E+ + AP V + +S ++++W P + +R + G G ++
Sbjct: 718 YIEELAPIVAPNFTVEDTSADS--ILVKWEDIPVEELRGFLRGYL-FYFGKGERDTSKMR 774
Query: 198 ILE-GRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSE-------PVSLLTPSDLD 249
+LE GR++ + N+ ++ T + + S+ A+++ + ++T +
Sbjct: 775 VLESGRSDIKVKNITDISQKTLRIADLQGKTSYHLVLRAYTDGGVGPEKSMYVVTKENSV 834
Query: 250 PLILTLSLILVVILVLLTVLALLSHRRA--LKQKIWPGIPSPESEFEGLFTTHKGNFQLW 307
LI+ + + + V +++ V ++L +R+ +K+ +P IP+PE N +
Sbjct: 835 GLIIAILIPVAVAVIVGVVTSILCYRKREWIKETFYPDIPNPE------------NCKAL 882
Query: 308 LYQNDGC--------LWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLE-P 358
+Q C L +PCT P ++EVL R +E T+ P+ E P
Sbjct: 883 QFQKSVCEGSSALKTLEMNPCT------PNNVEVLETR--SAFPKIE-DTEIISPVAERP 933
Query: 359 VGSEHAQDTYLVLDKWLLPRNPP--SEDLPGP-----GGSVDIVAMD 398
A+ V+ + PP E++P P GG+ ++ +D
Sbjct: 934 EDRSDAEPENHVVVSYC----PPIIEEEIPNPAADEAGGTAQVIYID 976
>gi|51093381 leptin receptor isoform 3 [Homo sapiens]
Length = 958
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 13/151 (8%)
Query: 109 LPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLL--DAPVGLVARLADESGHVVLRW 166
+PTA + + + L++T+ G ++ + + ++ D P+GL + D+ G++ + W
Sbjct: 200 VPTAKLNDTLLMCLKITSG-GVIFQSPLMSVQPINMVKPDPPLGLHMEITDD-GNLKISW 257
Query: 167 LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAE 226
PP P ++Y+V S N ++ + + T ++ ++ + Y VR + +
Sbjct: 258 SSPPLVPFP--LQYQVKYSE-NSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLD 314
Query: 227 PSFGGFWSAWSEPVSLLTPSDL---DPLILT 254
G WS WS P + T D+ P ILT
Sbjct: 315 GP--GIWSDWSTP-RVFTTQDVIYFPPKILT 342
>gi|51093379 leptin receptor isoform 2 [Homo sapiens]
Length = 896
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 13/151 (8%)
Query: 109 LPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLL--DAPVGLVARLADESGHVVLRW 166
+PTA + + + L++T+ G ++ + + ++ D P+GL + D+ G++ + W
Sbjct: 200 VPTAKLNDTLLMCLKITSG-GVIFQSPLMSVQPINMVKPDPPLGLHMEITDD-GNLKISW 257
Query: 167 LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAE 226
PP P ++Y+V S N ++ + + T ++ ++ + Y VR + +
Sbjct: 258 SSPPLVPFP--LQYQVKYSE-NSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLD 314
Query: 227 PSFGGFWSAWSEPVSLLTPSDL---DPLILT 254
G WS WS P + T D+ P ILT
Sbjct: 315 GP--GIWSDWSTP-RVFTTQDVIYFPPKILT 342
>gi|40254464 leptin receptor isoform 1 [Homo sapiens]
Length = 1165
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/151 (23%), Positives = 71/151 (47%), Gaps = 13/151 (8%)
Query: 109 LPTADTSSFVPLELRVTAASGAPRYHRVIHINEVVLL--DAPVGLVARLADESGHVVLRW 166
+PTA + + + L++T+ G ++ + + ++ D P+GL + D+ G++ + W
Sbjct: 200 VPTAKLNDTLLMCLKITSG-GVIFQSPLMSVQPINMVKPDPPLGLHMEITDD-GNLKISW 257
Query: 167 LPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAE 226
PP P ++Y+V S N ++ + + T ++ ++ + Y VR + +
Sbjct: 258 SSPPLVPFP--LQYQVKYSE-NSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLD 314
Query: 227 PSFGGFWSAWSEPVSLLTPSDL---DPLILT 254
G WS WS P + T D+ P ILT
Sbjct: 315 GP--GIWSDWSTP-RVFTTQDVIYFPPKILT 342
>gi|21361766 zinc finger protein 692 isoform 2 [Homo sapiens]
Length = 519
Score = 38.9 bits (89), Expect = 0.011
Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 36/193 (18%)
Query: 266 LTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPC---TP 322
L L LLSH + + + PG+ P + GL +W W P TP
Sbjct: 80 LQYLVLLSHAHSRECSLVPGLRGPGGQDGGL---------VWECSAGHTFSWGPSLSPTP 130
Query: 323 FTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPR--NP 380
PASL + R W + G L + SEH + T + LPR P
Sbjct: 131 SEAPKPASLPHTTRRSWCSEAT-------SGQELADLESEHDERT----QEARLPRRVGP 179
Query: 381 PSEDLPGPG---GSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLR 437
P E P PG G + ++ E S +S SP+ + D L
Sbjct: 180 PPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEP--------DAPRLLPS 231
Query: 438 PWTLCPELPPTPP 450
P T P+ TPP
Sbjct: 232 PVTCTPKEGETPP 244
>gi|209862873 zinc finger protein 692 isoform 1 [Homo sapiens]
Length = 524
Score = 38.9 bits (89), Expect = 0.011
Identities = 51/193 (26%), Positives = 69/193 (35%), Gaps = 36/193 (18%)
Query: 266 LTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSPC---TP 322
L L LLSH + + + PG+ P + GL +W W P TP
Sbjct: 85 LQYLVLLSHAHSRECSLVPGLRGPGGQDGGL---------VWECSAGHTFSWGPSLSPTP 135
Query: 323 FTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLPR--NP 380
PASL + R W + G L + SEH + T + LPR P
Sbjct: 136 SEAPKPASLPHTTRRSWCSEAT-------SGQELADLESEHDERT----QEARLPRRVGP 184
Query: 381 PSEDLPGPG---GSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLR 437
P E P PG G + ++ E S +S SP+ + D L
Sbjct: 185 PPETFPPPGEEEGEEEEDNDEDEEEMLSDASLWTYSSSPDDSEP--------DAPRLLPS 236
Query: 438 PWTLCPELPPTPP 450
P T P+ TPP
Sbjct: 237 PVTCTPKEGETPP 249
>gi|4504647 interleukin 13 receptor, alpha 1 precursor [Homo
sapiens]
Length = 427
Score = 38.5 bits (88), Expect = 0.015
Identities = 64/291 (21%), Positives = 116/291 (39%), Gaps = 44/291 (15%)
Query: 49 ELLCFTERLEDLVCFWEEAASAGVGPGNYSFSYQLEDEPW--KLCRLHQAPTA-RGAVRF 105
EL C L + C W + NY+ Y W L ++HQ R F
Sbjct: 131 ELQCIWHNLSYMKCSWLPGRNTSPDT-NYTLYY------WHRSLEKIHQCENIFREGQYF 183
Query: 106 WCS--LPTADTSSFVPLELRVTAASGAPRYH---RVIHINEVVLLDAPVGLVARLADESG 160
CS L SSF +++ A + ++ + V D P + L+ +
Sbjct: 184 GCSFDLTKVKDSSFEQHSVQIMVKDNAGKIKPSFNIVPLTSRVKPDPPH--IKNLSFHND 241
Query: 161 HVVLRWLPPPETPMTSHIRYEVDVSAG----NGAGSVQRVEI--------LEGRTECVLS 208
+ ++W P+ ++ + YEV+V+ + VQ + +E + ++
Sbjct: 242 DLYVQW-ENPQNFISRCLFYEVEVNNSQTETHNVFYVQEAKCENPEFERNVENTSCFMVP 300
Query: 209 NLRGRTRYTFAVRARMAEPSFGG--FWSAWSEPVSLLTPSDLDPLILTLSLILVVILVLL 266
+ T T +R + + + WS WS+ +S+ + L +T+ L++V ++V
Sbjct: 301 GVLPDTLNTVRIRVKTNKLCYEDDKLWSNWSQEMSIGKKRN-STLYITM-LLIVPVIVAG 358
Query: 267 TVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWW 317
++ LL + + LK I+P IP P F+ +F QND L W
Sbjct: 359 AIIVLLLYLKRLKIIIFPPIPDPGKIFKEMFGD----------QNDDTLHW 399
>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
[Homo sapiens]
Length = 918
Score = 37.4 bits (85), Expect = 0.032
Identities = 37/171 (21%), Positives = 66/171 (38%), Gaps = 23/171 (13%)
Query: 191 GSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLDP 250
G+ V + TE LS+L T Y + A E G ++ P +++
Sbjct: 563 GNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPK--FAQGEIEA 620
Query: 251 LILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQ 310
+++ + L + + LL VL + R +K+ IWP +P P
Sbjct: 621 IVVPVCLAFL-LTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSH----------------- 662
Query: 311 NDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGS 361
WSP TP + + ++ S+ + + VE +D+ P E + S
Sbjct: 663 ---IAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKS 710
Score = 30.4 bits (67), Expect = 4.0
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 202 RTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD 247
R+ + +L+ T Y F +R + G+WS WSE S +T D
Sbjct: 281 RSSFTVQDLKPFTEYVFRIRCMKEDGK--GYWSDWSEEASGITYED 324
>gi|5031785 interleukin 12 receptor, beta 1 isoform 1 precursor
[Homo sapiens]
Length = 662
Score = 36.2 bits (82), Expect = 0.072
Identities = 49/173 (28%), Positives = 68/173 (39%), Gaps = 25/173 (14%)
Query: 203 TECVLSNLRGRTRYTFAVRARMAEPSFGGFW--SAWSEPVSLLTPSDL-DPLILTLSLIL 259
T+ LS LR YT VRA A W WS+P + D LI SL
Sbjct: 503 TQVTLSGLRAGVAYTVQVRADTA-------WLRGVWSQPQRFSIEVQVSDWLIFFASLGS 555
Query: 260 VVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWWSP 319
+ ++L+ VL L RA + + P +P+P + F K +Q W +P
Sbjct: 556 FLSILLVGVLGYLGLNRAARH-LCPPLPTPCASSAIEFPGGKETWQ----------WINP 604
Query: 320 CTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLD 372
F E+ ++ E W + EP E P P E A DT L L+
Sbjct: 605 -VDFQEEASLQEALVVEMSWDKGERTEPLEKTELPEGAP---ELALDTELSLE 653
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 35.4 bits (80), Expect = 0.12
Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 7/93 (7%)
Query: 386 PGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLRPWTLCPEL 445
PGP G G + S S L P P+G + ++L P L +C +
Sbjct: 512 PGPSGP-------PGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDC 564
Query: 446 PPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQG 478
PP PP L L D G+ ++G +G
Sbjct: 565 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKG 597
>gi|149944516 tet oncogene family member 3 [Homo sapiens]
Length = 1660
Score = 34.7 bits (78), Expect = 0.21
Identities = 45/173 (26%), Positives = 63/173 (36%), Gaps = 39/173 (22%)
Query: 374 WLLPRNPPSEDLPGPGGSV------DIVAMDEGSEASSCSSALASK-------------- 413
W + + P E PGP + D+VA +EA S AL+++
Sbjct: 39 WRVDQKPDWEAAPGPAHTARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFNREMSREAG 98
Query: 414 -------PSPEGASAASFEYTILDPSSQLLRPWTLCPEL----PPTPPHLKYL----YLV 458
P PEG SA S + L + L R P P P +L++L V
Sbjct: 99 NNSRGPRPGPEGCSAGSEDLDTLQTALALARHGMKPPNCNCDGPECPDYLEWLEGKIKSV 158
Query: 459 VSDSGISTDYSSGDSQGAQGGLSDGPYSNPYENSLIPAAEP---LPPSYVACS 508
V + G G + GL P + P +S +P P LP S A S
Sbjct: 159 VMEGGEERPRLPGPLPPGEAGL-PAPSTRPLLSSEVPQISPQEGLPLSQSALS 210
>gi|115430248 gp130-like monocyte receptor [Homo sapiens]
Length = 764
Score = 34.7 bits (78), Expect = 0.21
Identities = 50/235 (21%), Positives = 82/235 (34%), Gaps = 18/235 (7%)
Query: 10 PQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAAS 69
P +L ++ A W P KF S AAL A PE + C ++L C W
Sbjct: 26 PSCVNLGMMWTWALWMLPSLC---KF-SLAALPAK--PENISCVYYYRKNLTCTWSPGKE 79
Query: 70 AGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAASG 129
+Y ++ R + F+ LP +E+ G
Sbjct: 80 TSYTQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFF--LPRITIPDNYTIEVEAENGDG 137
Query: 130 APRYHRVIHINEVVLLDAPVGL--VARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAG 187
+ H E + P + V + + + W+ P P++S ++Y +
Sbjct: 138 VIKSHMTYWRLENIAKTEPPKIFRVKPVLGIKRMIQIEWIKPELAPVSSDLKYTLRFRTV 197
Query: 188 NGAGSVQRVEILEGRTE----CVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSE 238
N S V + R + L+ L+ T Y A+R + E FWS WS+
Sbjct: 198 NST-SWMEVNFAKNRKDKNQTYNLTGLQPFTEYVIALRCAVKESK---FWSDWSQ 248
Score = 30.8 bits (68), Expect = 3.0
Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 12/147 (8%)
Query: 162 VVLRWLPPPETPMTSHI-RYEVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAV 220
V + W P++ I Y + A G G + V + L +L+ +T Y V
Sbjct: 469 VTITWKEIPKSERKGIICNYTIFYQAEGGKGFSKTVN--SSILQYGLESLKRKTSYIVQV 526
Query: 221 RARMAEPSFGGFWSAWSEPVSLLTPSDLDPLILTLSLIL--VVILVLLTVLALLSHRRAL 278
MA S GG + S L+ S + +++T SLI ++IL++LTV L L
Sbjct: 527 ---MASTSAGGT-NGTSINFKTLSFSVFEIILIT-SLIGGGLLILIILTVAYGLKKPNKL 581
Query: 279 KQKIWPGIPSPESEFEGLFTTHKGNFQ 305
WP +P+P + T H +F+
Sbjct: 582 THLCWPTVPNPAE--SSIATWHGDDFK 606
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 34.3 bits (77), Expect = 0.28
Identities = 44/168 (26%), Positives = 56/168 (33%), Gaps = 32/168 (19%)
Query: 66 EAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVT 125
E A PG F ++ + P C H P+ GA C P + T
Sbjct: 270 EDACQACSPG--FFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQD-PASMPCT 326
Query: 126 AASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDV- 184
AP Y VG+ A+ V LRW PP ++ I Y V
Sbjct: 327 RPPSAPHYLTA------------VGMGAK-------VELRWTPPQDSGGREDIVYSVTCE 367
Query: 185 -------SAGNGAGSVQRVEILEG--RTECVLSNLRGRTRYTFAVRAR 223
G SV+ E G RT +S+L YTF V AR
Sbjct: 368 QCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEAR 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,919,733
Number of Sequences: 37866
Number of extensions: 1327640
Number of successful extensions: 4411
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 78
Number of HSP's that attempted gapping in prelim test: 4339
Number of HSP's gapped (non-prelim): 147
length of query: 508
length of database: 18,247,518
effective HSP length: 107
effective length of query: 401
effective length of database: 14,195,856
effective search space: 5692538256
effective search space used: 5692538256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.